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Non-invasive management of suppurative skin nodule (metastatic cutaneous abscess): a suspected case of tuberculous gumma: “a case report.” 化脓性皮肤结节(转移性皮肤脓肿)的非侵入性治疗:1例疑似结核性牙龈瘤:1例报告。
Pub Date : 2022-07-01 DOI: 10.4103/jism.jism_35_22
 . Reetu, D. Kajaria
The paradigm of cutaneous adverse drug reactions (CADRs) due to the resurgence of Dushi-visha (~cumulative poison) is less reported. Clinical evidence of Dushi-visha is not commonly diagnosed in the clinics. This is the era of polypharmacy; the long duration of medication along with a multi-therapeutic approach causes drug intolerance and complicates with reduced assimilation. Improper elimination causes an increased concentration of these medicines in the plasma and produces toxic side effects. These cumulative endotoxins are termed as Dushi-visha in Ayurveda. A 60-year-old male diagnosed with abdominal tuberculosis had undergone anti-tubercular treatment and suffered from pyogenic abscess over back, and rectal area, around the umbilical area. Pus culture isolated coagulase-negative Staphylococcus. In due course of time, the patient took treatment but abscess continued to develop over different parts of the body. This is a suspected case of tuberculous gumma based on clinical presentation and history of the disease, and according to Ayurveda, this is a case of Dushi-visha. The classical treatment of an abscess is focussed on incision and drainage, but this case was handled with Vishaghna chikitsa (~anti-toxin treatment) and other potential treatments considering the resurgence of Dushi-visha without any surgical intervention. Many conditions, which generally seem idiopathic due to lack of proper history, may be due to reactivation of Dushi-visha. This case report opens up the way to clinically identify and potentially treat the condition with Ayurveda.
皮肤药物不良反应(CADRs)的范式,由于复发的Dushi-visha(~累积中毒)报道较少。临床证据在临床上并不常见。这是一个多药并存的时代;长时间的药物治疗以及多种治疗方法导致药物不耐受和同化减少的并发症。不适当的排除会导致这些药物在血浆中的浓度增加并产生毒副作用。这些累积的内毒素在阿育吠陀中被称为Dushi-visha。60岁男性,确诊为腹部结核,经抗结核治疗后背部、直肠、脐周围出现化脓性脓肿。脓液培养分离凝固酶阴性葡萄球菌。在适当的时候,病人接受了治疗,但脓肿继续在身体的不同部位发展。根据临床表现和病史,这是一个疑似结核性牙龈瘤病例,根据阿育吠陀医学,这是一个Dushi-visha病例。脓肿的经典治疗方法是切口引流,但本病例采用了抗毒素治疗和其他潜在的治疗方法,考虑到Dushi-visha的复发,没有任何手术干预。许多由于缺乏适当的病史而通常被认为是特发性的疾病,可能是由于Dushi-visha的重新激活。本病例报告为临床识别和潜在治疗阿育吠陀疾病开辟了道路。
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引用次数: 1
In-vivo evaluation of chondroprotective activity of Ariflex tablet in comparison with aceclofenac tablet and chondroitin sulfate/glucosamine (CG) in monosodium iodoacetate-induced osteoarthritis in rats 阿立弗来片与醋酸氯芬酸片和硫酸软骨素/氨基葡萄糖(CG)对大鼠碘乙酸钠诱导的骨关节炎的体内软骨保护活性比较
Pub Date : 2022-07-01 DOI: 10.4103/jism.jism_49_22
S. Nipanikar, M. Patil, P. Kadam
Background: Degenerative changes in a joint subsequent to alterations in cartilage formation equilibrium lead to development of osteoarthritis (OA). Aims: Chondroprotective activity of Ariflex tablet (a polyherbal formulation) was evaluated in comparison with chondroitin/glucosamine and aceclofenac in monosodium iodoacetate-induced OA in Wistar rat models. Materials and Methods: A total of 42 animals were divided into seven groups, viz., four control groups [negative, positive, standard and vehicle controls] and three test groups [low, medium, and high dosages]. Animals in seven groups were treated with various study drugs for the period of 28 days. In this study period, measurement of body weight and knee joint swelling was done periodically. Gait score was recorded on the last day, and histopathological examination of joints was done after sacrificing the animals. Results: Chondroprotective activity of medium and high dose of Ariflex tablet was comparable to that of aceclofenac and superior to chondroitin + glucosamine combination. In few rats of medium and high dose of Ariflex tablet groups, chondrocyte regeneration and formation of new blood vessels were seen, which indicated possibility of chondrocyte regeneration activity of Ariflex tablet. Conclusion: Ariflex tablet possesses significant chondroprotective activity comparable to aceclofenac and superior to chondroitin and glucosamine combination. There was a possibility of chondrocyte regeneration activity of Ariflex tablet, which can be confirmed by conducting another study with long-term treatment.
背景:关节退行性改变导致软骨形成平衡的改变导致骨关节炎(OA)的发展。目的:通过与软骨素/氨基葡萄糖和乙酰氯芬酸对Wistar大鼠OA模型的软骨保护作用进行比较,评价阿立弗来片(一种多草药制剂)的软骨保护作用。材料与方法:42只动物分为7组,即4个对照组(阴性、阳性、标准、载体对照)和3个试验组(低、中、高剂量)。七组动物分别服用不同的研究药物,疗程28天。在研究期间,定期测量体重和膝关节肿胀。最后一天记录步态评分,并在献祭后对关节进行组织病理学检查。结果:Ariflex中、高剂量片的软骨保护活性与乙酰氯芬酸相当,优于软骨素+氨基葡萄糖联合用药。阿立弗片中、高剂量组少数大鼠出现软骨细胞再生和新血管形成,提示阿立弗片可能具有软骨细胞再生活性。结论:Ariflex片具有与乙酰氯芬酸相当的显著的软骨保护活性,优于软骨素与氨基葡萄糖联合使用。Ariflex片存在软骨细胞再生活性的可能性,这可以通过另一项长期治疗的研究来证实。
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引用次数: 0
Transitional curriculum (foundation course) for batch 2021–2022: Report 2021-2022学年过渡课程(基础课程):报告
Pub Date : 2022-07-01 DOI: 10.4103/jism.jism_80_22
A. Deshpande, G. Sawarkar
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引用次数: 0
Ayurved management of a case of intensive Dadru (dermatophytosis)—A case report 重症皮肤真菌病1例的治疗
Pub Date : 2022-07-01 DOI: 10.4103/jism.jism_46_22
Medha Lakkawar, Pratima Gaikwad, A. More, Shalini Rai
Introduction: Dermatophytosis (tinea) infections are superficial fungal diseases caused by dermatophytes, a fungus genus that penetrates and grows in dead keratin leading to reddish-colored erythematous cutaneous eruptions in circular lesions presenting with itching. If neglected, fungal infections are more likely to come back and can cause the emergence of more severe conditions. Relapses and recurrences demonstrate that the pathogenic organism is not simply eradicated, demanding more research to create new therapeutic options. Numerous medications used in Ayurveda are thought to have the Krimighna effect, which can result in a more effective course of therapy. Dermatophytosis can be simulated with Dadru Kushtha because the clinical characteristics of the disease are more closely related to those of dermatophytosis. Materials and Methods: This case report documents the case of a 37-year-old female patient with complaints of red circular patches and elevated edges over genitals, groin, flanks, axilla, and forehead regions with severe itching diagnosed with Dadru Kushtha. The case was intervened with Ayurvedic Shaman (pacifying therapy) and Bahirparimarjana chikitsa (external therapy). Result: A significant reduction was observed in Kandu, Daha, Raga, number and size of Mandala, and Pidaka after treatment and after follow-up. Conclusion: Dermatophytosis can be successfully treated with Ayurvedic oral and topical treatments, dietary and lifestyle limitations, and personal hygiene.
简介:皮肤癣(癣)感染是由皮肤癣菌引起的浅表真菌疾病,一种真菌属,可渗透并生长在死亡的角蛋白中,导致圆形病变中出现红色红斑性皮肤疹,并伴有瘙痒。如果忽视,真菌感染更有可能复发,并可能导致更严重的情况的出现。复发和复发表明,致病生物不是简单地根除,需要更多的研究来创造新的治疗选择。阿育吠陀中使用的许多药物被认为具有krimiganna效应,这可以导致更有效的治疗过程。皮肤病可以用Dadru Kushtha模拟,因为该病的临床特征与皮肤病的临床特征更密切相关。材料和方法:本病例报告记录了一名37岁女性患者,其主诉为生殖器、腹股沟、侧腹、腋窝和前额区域出现红色圆形斑块和边缘升高,并伴有严重瘙痒,诊断为达德鲁库什塔。该病例通过阿育吠陀萨满(安抚疗法)和Bahirparimarjana chikitsa(外部疗法)进行干预。结果:治疗后及随访后,大鼠Kandu、Daha、Raga、Mandala、Pidaka的数量和大小均显著降低。结论:通过阿育吠陀口服和局部治疗、限制饮食和生活方式以及个人卫生,可以成功治疗皮肤真菌病。
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引用次数: 0
Pharmacognostical and phytochemical standardization on stem bark of Mahonia nepalensis DC.: An extrapharmacopoeial plant 尼泊尔Mahonia nepalensis DC茎皮的生药学和植物化学标准。一种药外植物
Pub Date : 2022-07-01 DOI: 10.4103/jism.jism_52_22
K. Paudel, A. Ramamurthy, G. Sharma
Introduction: The tribal people cure hepatic-related disorders with the stem bark of Mahonia nepalensis DC. Aim: The aim of the study was to do Investigation of the Microscopic and Macroscopic Characteristics, Pharmacognostical, Physiochemical Parameters, and Thin Layer Chromatography of Stem Bark of Mahonia nepalensis DC. Materials and Methods: Mahonia nepalensis DC. were collected from natural habitat and authenticated by the proper plant authentication centers. The cell composition of TS slices was examined after they had been dyed and mounted. The powders of the sample drug were studied organoleptically. The Extractive values and Ash values were represented in Pie-chart form designed by using Microsoft Excel. Results: The Bark of the Mahonia nepalensis DC. is brown in color externally but the inner side is yellow with features of general anatomy of dicot stem on transverse section. The pharmacognosy and phytochemical investigations of the stem bark of Mahonia nepalensis DC shows presence of starch grain, intermedullary rays as diagnostic characters. Mayer’s reagent test and Dragon Droff’s reagent test are positive in the test signifies that the present of Alkaloids and TLC values were evaluated. Conclusion: The key diagnostic characteristics of Mahonia nepalensis DC’s stem were identified from its pharmacognosy. The stem of Mahonia nepalensis DC was authenticated and subjected to quality control using phytochemical tests and TLC, which were derived and described.
简介:部落居民用尼泊尔Mahonia nepalensis DC的茎皮治疗肝脏相关疾病。目的:研究尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马honia尼泊尔马的显微、宏观特征、生药学、理化参数和薄层色谱。材料与方法:尼泊尔毛楝。采自自然生境,经适当的植物鉴定中心鉴定。TS切片染色、贴装后检测细胞组成。对样品药物的粉末进行了感官研究。Extractive值和Ash值采用Microsoft Excel设计的饼图形式表示。结果:尼泊尔Mahonia nepalensis DC的树皮。外呈褐色,内呈黄色,横切面具有双茎的一般解剖特征。对尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔Mahonia尼泊尔MahoniaMayer试剂检测和Dragon Droff试剂检测结果均为阳性,说明生物碱的存在性和TLC值得到了评价。结论:从生药学角度确定了尼泊尔毛臭茎的主要诊断特征。本文采用植物化学试验和薄层色谱法对尼泊尔Mahonia nepalensis DC茎进行了鉴定和质量控制。
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引用次数: 1
Report on national webinar on “Rasayan and Vajikaran” “Rasayan与Vajikaran”全国网络研讨会报告
Pub Date : 2022-04-01 DOI: 10.4103/jism.jism_33_22
Sadhana Misar Wajpeyi
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引用次数: 0
Understanding Charaka Samhita in light of Samanya-Vishesha Siddhanta: a bird’s eye view 根据《沙曼雅-毗瑟沙悉达多》来理解《查罗伽·沙曼塔》:鸟瞰
Pub Date : 2022-04-01 DOI: 10.4103/jism.jism_97_21
Suman Meghwal, S. Bhatnagar
The concept of Samanya-Vishesha (similarity and dissimilarity) is one of the major ideologies of Ayurveda. These are widely described and implemented in Charaka Samhita and are mentioned under six factors required for the action of Dhatusamya (equilibrium) in the body. Many scholars face difficulty in understanding the meaning and implementation of these principles. Elementary knowledge and clear understanding of the fundamental principles is very necessary and of utmost importance for their practical implementation. So, it is mandatory to understand these principles in a descriptive manner. An effort has been made to comprehend Charaka Samhita in the light of Samanya-Vishesha Siddhanta in this study. The facts have been collected from Charaka Samhita along with Ayurvedadipika Sanskrita commentary and its Hindi and English translations. Indian philosophical texts have also been referred. The matter has been extensively explored, systematically organized followed by rational analysis. After exploration and analysis it was concluded that the systematic organization of Charaka Samhita, etiology, symptoms and treatment of the diseases are basically dependent on these principles.
Samanya-Vishesha(相似和不同)的概念是阿育吠陀的主要意识形态之一。这些在《查拉卡·三观》中被广泛地描述和实施,并在身体内达图萨米亚(平衡)行动所需的六个因素下被提到。许多学者在理解这些原则的含义和实施方面面临困难。基本的知识和对基本原则的清晰理解是非常必要的,对它们的实际实施至关重要。因此,必须以描述性的方式理解这些原则。在这项研究中,我们已经努力去理解《沙曼雅-毗舍沙悉达多》。这些事实收集自《查拉卡·萨姆希塔》,以及《阿育吠陀》梵文评论及其印地语和英语翻译。印度哲学文献也被提及。这件事经过了广泛的探索,系统的组织,然后进行了理性的分析。经过探索和分析,认为查罗三经的系统组织、病因、症状和疾病的治疗基本上都依赖于这些原理。
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引用次数: 0
A narrative review on use of virgin coconut oil in dermatology
Pub Date : 2022-04-01 DOI: 10.4103/jism.jism_34_22
Nishigandha Umate, Vaishali Kuchewar, Shweta Parwe
Background: Coconut oil is of two varieties: virgin and refined oil. Virgin coconut oil (VCO) is made by cold-pressing the liquid from the fresh part of coconut meat. It has a milky appearance. This oil extraction method prevents the loss of vitamin E, pro-vitamin A, and polyphenols. It has various properties such as analgesic, anti-inflammatory, and anti-cancer. Skin is the general structure of the body. It is the first line of protection against traumatic injuries and microorganisms. Aim: This review is focussed on the existing data on the effect of VCO on the skin. Materials and Methods: PubMed and Google Scholar were searched for citations for keywords “virgin coconut oil and dermatology” and “virgin coconut oil and skin.” In search of the various databases, 13 articles were found on VCO related to skin. Result: Virgin coconut oil is used as antioxidant, anti-inflammatory, as skin protector, in Alzheimer’s disease, in wound healing and as moisturizer. Conclusion: From this review, it can be concluded that VCO is beneficial for various dermatological disorders. It is antifungal and antibacterial and also acts as an immunomodulator. It also has anti-inflammatory, angiogenic, wound-healing, and skin protective properties.
背景:椰子油有两种:初榨油和精炼油。初榨椰子油(VCO)是由椰子肉新鲜部分的液体冷压制成的。它有乳白色的外观。这种榨油方法可以防止维生素E、维生素A原和多酚的流失。它具有镇痛、抗炎、抗癌等多种特性。皮肤是身体的总体结构。它是防止创伤和微生物的第一道防线。目的:本文综述了VCO对皮肤影响的现有数据。材料和方法:在PubMed和谷歌Scholar上搜索关键词“初榨椰子油和皮肤学”和“初榨椰子油和皮肤”的引文。在各种数据库中检索到13篇与皮肤相关的VCO文章。结果:初榨椰子油被用作抗氧化、抗炎、皮肤保护、阿尔茨海默病、伤口愈合和保湿剂。结论:VCO对多种皮肤病有一定的治疗作用。它是抗真菌和抗菌,也作为一种免疫调节剂。它还具有抗炎、血管生成、伤口愈合和皮肤保护的特性。
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引用次数: 1
Therapeutic aspects of Kashtartava (dysmenorrhea) in Ayurveda: a review 阿育吠陀治疗痛经的方法综述
Pub Date : 2022-04-01 DOI: 10.4103/jism.jism_90_21
Monika Goel, Rohit Singh, Unnati Bidhoodi
Kashtartava (painful menstruation or dysmenorrhea) is one of the common gynecological disorders observed among women. It has been described as a symptom of various diseases such as Kukshishoola, Vatala yoni, Udavartini yonivyapada, etc. in Ayurvedic classics. It is characterized by a condition in which Artava (menstrual fluid) is shedded with great difficulty and pain. Acharya Charaka has specifically mentioned that none of the gynecological disorders can arise without the involvement of vitiated Vata dosha (a type of body humor). The pain produced in dysmenorrhea is due to vitiation of Vata dosha only or in combination with other Doshas, which is the result of Vatavriddhi (elevation in the Vata level) due to Apanavayu (type of Vata), margavarodha (obstruction of channel), etc. It has been reported that around 90% of adolescent females and above 50% of menstruating women worldwide reported suffering from it, with 10–20% of them describing their suffering as severe and distressing. Owing to these facts, various classical texts of Ayurveda have been reviewed and literature search was performed using the keywords “Kashtartava, Dysmenorrhea, Menstrual pain, Menstruation, Yoni vyapada (vaginal disorder)” in various online databases in order to collect the data regarding the same. It has been revealed that Dhatukshaya (depletion of body tissues), Kopa (aggravation of Doshas), and Margavarodha (obstruction of channel) are the three prime conditions which lead to the vitiation of Vata dosha resulting in dysmenorrhea. It can be managed with various Ayurvedic preparations such as Phala ghrita, Jeerakadi modak, Maharasnadi kwath, etc. Panchkarma (five therapeutic biodetoxification procedures) such as Shatavaryadi anuvasana basti and Baladi anuvasana basti is also proved to be beneficial along with Pathya ahara and Vihara (wholesome regulated diet and lifestyle).
痛经(痛经或痛经)是女性常见的妇科疾病之一。在阿育吠陀经典中,它被描述为各种疾病的症状,如Kukshishoola, Vatala yoni, Udavartini yonivyapada等。它的特点是分泌经液时非常困难和痛苦。阿查里亚·查罗卡特别提到,如果没有被破坏的Vata dosha(一种身体幽默)的参与,任何妇科疾病都不会出现。痛经产生的疼痛仅仅是由于Vata dosha的破坏或与其他dosha的结合,这是由于Apanavayu (Vata类型),margavarodha(通道阻塞)等导致的Vatavriddhi (Vata水平升高)的结果。据报道,全世界约90%的青春期女性和50%以上的经期女性报告患有这种疾病,其中10-20%的人将其痛苦描述为严重和痛苦。由于这些事实,我们对阿育吠陀的各种经典文本进行了回顾,并在各种在线数据库中使用关键词“Kashtartava,痛经,经痛,月经,Yoni vyapada(阴道紊乱)”进行了文献检索,以收集与之相关的数据。据揭示,Dhatukshaya(身体组织耗竭),Kopa(多沙加重)和Margavarodha(经络阻塞)是导致Vata多沙损害导致痛经的三个主要条件。它可以用各种阿育吠陀制剂来管理,如Phala ghrita、Jeerakadi modak、Maharasnadi kwath等。Panchkarma(五种治疗性生物排毒程序),如Shatavaryadi anuvasana basi和Baladi anuvasana basi,也被证明与Pathya ahara和Vihara(健康的调节饮食和生活方式)一起有益。
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引用次数: 0
Effect of Vamana Karma (therapeutic emesis) in Mukhadushika (acne vulgaris)—A case study Vamana Karma(治疗性呕吐)对寻常痤疮的疗效——个案研究
Pub Date : 2022-04-01 DOI: 10.4103/jism.jism_27_22
H. Shende, S. Bhatted
Acne vulgaris is a chronic skin disease that comes about mostly in adolescent. It is identified by both inflammatory (papules, pustules, and nodules) and noninflammatory (comedones, open and closed) lesions. In the Ayurvedic classics, Mukhadushika is mentioned under Kshudra Rogas, which is declared that it transpires in young age, and its signs and symptoms are similar to those of acne vulgaris. In the Ayurvedic classics, Mukhadushika is mentioned under Kshudra Rogas, which is stated that it occurs in young age and its manifestations are similar to those of acne vulgaris. In Ayurveda, it is mentioned that Mukhadushika occurs due to the vitiation of Vata, Kapha, and Rakta having the Shalmali thorn like thick or hard painful eruptions, which are impregnated with Meda. Vamana karma is indicated for the treatment of Mukhadushika. This is a single case study on the effective management of Mukhadushika. Treatments included are Deepana, Pachana with Chitrakadi Vati and Musta Choorna, Shodhananga Snehapana with Tiktak Ghrita and Vamana Karma (therapeutic emesis) with Madanphala Yoga. After the completion of Vamana Karma (therapeutic emesis), a significant relief in signs and symptoms of Mukhadushika was observed. On the account of result acquired, it can be deduced that Vamana Karma (therapeutic emesis) with Madanphala Yoga can be used as an effective treatment for Mukhadushika and improve the quality of life in the patients of Mukhadushika.
寻常痤疮是一种常见于青少年的慢性皮肤病。它可以通过炎性(丘疹、脓疱和结节)和非炎性(粉刺、开放性和闭合性)病变来识别。在阿育吠陀经典中,mukkhadushika被提到在Kshudra Rogas下,它被宣布在年轻时发生,其体征和症状与寻常痤疮相似。在阿育吠陀经典中,mukkhadushika在Kshudra Rogas下被提到,据说它发生在年轻时,其表现与寻常痤疮相似。在阿育吠陀中,提到Mukhadushika的发生是由于Vata, Kapha和Rakta的污染造成的,他们的沙玛里刺像厚厚的或坚硬的痛苦的喷发,这些刺充满了Meda。Vamana业力是用来治疗Mukhadushika的。这是一个关于Mukhadushika有效管理的单一案例研究。治疗包括Deepana, Pachana与Chitrakadi Vati和Musta Choorna, Shodhananga Snehapana与Tiktak Ghrita和Vamana Karma(治疗呕吐)与Madanphala瑜伽。在完成Vamana Karma(治疗性呕吐)后,观察到Mukhadushika的体征和症状显著缓解。根据所获得的结果,可以推断,Madanphala瑜伽的治疗性呕吐(Vamana Karma)可以作为一种有效的治疗Mukhadushika的方法,并提高Mukhadushika患者的生活质量。
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引用次数: 0
期刊
Journal of Indian System of Medicine
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