R. Ranjan, Meenakshi, Mita Singh, R. Pal, J. Das, S. Gupta
Aim: Incidents of vandalism on doctors is increasing by alarming rate. It has been observed in all types of government and private set ups. This trend is observed pan India as well as globally. Methods: A descriptive analysis of reported data on vandalism on doctors from the Google search engine, all national and local news websites of the last 11 years from January 2006 to May 2017. Results: The number of cases reported was counted yearly which showed a remarkable increase in crime against doctors. Majority of the cases have been reported in media from Delhi and Maharashtra in the last 11 years. Out of 100 cases reported majority were witnessed in 2015 and 2016 (17 each) and followed by 2017 (14). Majority of the males suffered grievous injury (52.1%); this distribution was statistically significant (P = 0.001). The night shift contributed higher proportion of grievous injuries (52.9%) (P = 0.003). Conclusion: The source of this intolerance toward health-care providers stems from unlimited expectation (magic cure) from doctors on the one hand and unjustified expectation and limited health education of patients and their caregivers (attendants and bystanders) led them to believe that medical science has a curative solution for all the health problems even in the resource-rich settings.
{"title":"Epidemiology of violence against medical practitioners in a developing country (2006-2017)","authors":"R. Ranjan, Meenakshi, Mita Singh, R. Pal, J. Das, S. Gupta","doi":"10.4103/JHRR.JHRR_84_17","DOIUrl":"https://doi.org/10.4103/JHRR.JHRR_84_17","url":null,"abstract":"Aim: Incidents of vandalism on doctors is increasing by alarming rate. It has been observed in all types of government and private set ups. This trend is observed pan India as well as globally. Methods: A descriptive analysis of reported data on vandalism on doctors from the Google search engine, all national and local news websites of the last 11 years from January 2006 to May 2017. Results: The number of cases reported was counted yearly which showed a remarkable increase in crime against doctors. Majority of the cases have been reported in media from Delhi and Maharashtra in the last 11 years. Out of 100 cases reported majority were witnessed in 2015 and 2016 (17 each) and followed by 2017 (14). Majority of the males suffered grievous injury (52.1%); this distribution was statistically significant (P = 0.001). The night shift contributed higher proportion of grievous injuries (52.9%) (P = 0.003). Conclusion: The source of this intolerance toward health-care providers stems from unlimited expectation (magic cure) from doctors on the one hand and unjustified expectation and limited health education of patients and their caregivers (attendants and bystanders) led them to believe that medical science has a curative solution for all the health problems even in the resource-rich settings.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"9 1","pages":"153 - 160"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88679419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: To determine whether the frequency of Temporomandibular myofascial dysfunction (TMD) differs in patients treated for different mandibular and zygomatic fractures. Materials and Methods: This was a 9-year prospective study. The diagnosis of TMD was based on standard diagnostic criteria and was made during follow-up reviews of patients after the treatment of the fractures. Additional information obtained from the patients and their case files were age, gender, site of fracture (s), and treatment methods. One-way analysis of variance was used to compare the presence of TMD among the study groups. Results: Overall, 42/587 (7.2%) patients were diagnosed with TMD between 2.3 and 4.7 years after treatment commenced. Patients who presented with TMD were those treated for isolated zygomatic (n = 5/42, 11.9%), isolated condylar (n = 7/63, 10.0%), and multiple mandibular (n = 30/475, 6.3%) fractures, which was significant (P = 0.01) in favor of those treated for isolated zygomatic and isolated condylar fractures. Patients who were treated for unilateral zygomatic complex/arch(P == 0.001), unilateral intracapsular condyle (P = 0.001), and parasymphyseal/body/angle/condyle (P = 0.01) fractures also had higher frequencies of TMD. Conclusions: Patients who were treated for isolated zygomatic or condylar fractures had higher frequencies of TMD than those with multiple mandibular fractures. Future research work needs to be directed toward the description of the pathogenesis of the different types of TMD symptoms so that more information can be gathered on the natural course of the disorders and identify the risk factors for pain persistence and chronicity.
{"title":"Does the frequency of temporomandibular myofascial dysfunction differ in patients treated for different mandibular and zygomatic fractures?","authors":"C. Anyanechi","doi":"10.4103/JHRR.JHRR_98_17","DOIUrl":"https://doi.org/10.4103/JHRR.JHRR_98_17","url":null,"abstract":"Aim: To determine whether the frequency of Temporomandibular myofascial dysfunction (TMD) differs in patients treated for different mandibular and zygomatic fractures. Materials and Methods: This was a 9-year prospective study. The diagnosis of TMD was based on standard diagnostic criteria and was made during follow-up reviews of patients after the treatment of the fractures. Additional information obtained from the patients and their case files were age, gender, site of fracture (s), and treatment methods. One-way analysis of variance was used to compare the presence of TMD among the study groups. Results: Overall, 42/587 (7.2%) patients were diagnosed with TMD between 2.3 and 4.7 years after treatment commenced. Patients who presented with TMD were those treated for isolated zygomatic (n = 5/42, 11.9%), isolated condylar (n = 7/63, 10.0%), and multiple mandibular (n = 30/475, 6.3%) fractures, which was significant (P = 0.01) in favor of those treated for isolated zygomatic and isolated condylar fractures. Patients who were treated for unilateral zygomatic complex/arch(P == 0.001), unilateral intracapsular condyle (P = 0.001), and parasymphyseal/body/angle/condyle (P = 0.01) fractures also had higher frequencies of TMD. Conclusions: Patients who were treated for isolated zygomatic or condylar fractures had higher frequencies of TMD than those with multiple mandibular fractures. Future research work needs to be directed toward the description of the pathogenesis of the different types of TMD symptoms so that more information can be gathered on the natural course of the disorders and identify the risk factors for pain persistence and chronicity.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"8 1","pages":"66 - 70"},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84144473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-05-01DOI: 10.4103/jhrr.jhrr_106_17
G. Bhalla, N. Grover, Lavan Singh, M. Sarao, D. Kalra, Chetna Pandey
Aim: Nontuberculous mycobacteria (NTM) are proven pathogens causing a plethora of diseases in humans. Various methods are available for their identification and susceptibility testing. Since their susceptibility varies with species, it becomes imperative to perform drug susceptibility testing. Various methods are available, of which broth microdilution is recommended by the Clinical and Laboratory Standards Institute (CLSI). We report our results after using RAPMYCO, commercially available, predosed, ready-to-use broth-microdilution plate. Materials and Methods: A total of 33 isolates of NTM were tested using the RAPMYCO panel for susceptibility against amikacin, cefoxitin, ciprofloxacin, clarithromycin, doxycycline, imipenem, linezolid, trimethoprim + sulfamethoxazole, tobramycin, and tigecycline, and the results were interpreted as per the CLSI guidelines. Results and Conclusion: Minimum inhibitory concentration results of conventional broth microdilution correlated well with those of RAPMYCO. All Mycobacterium fortuitum and Mycobacterium chelonae isolates were susceptible to amikacin and tobramycin.Good susceptibility was observed towards clarithromycin for all isolates; some degree of susceptibility was observed for quinolones and linezolid. High degree of resistance was seen for cefoxitin, doxycycline, and trimethoprim + sulfamethoxazole. Mycobacterium abscessus was the most resistant. RAPMYCO was simple, easy, and saved precious person-hours as compared to conventional broth microdilution.
{"title":"RAPMYCO: Mitigating conventional broth microdilution woes","authors":"G. Bhalla, N. Grover, Lavan Singh, M. Sarao, D. Kalra, Chetna Pandey","doi":"10.4103/jhrr.jhrr_106_17","DOIUrl":"https://doi.org/10.4103/jhrr.jhrr_106_17","url":null,"abstract":"Aim: Nontuberculous mycobacteria (NTM) are proven pathogens causing a plethora of diseases in humans. Various methods are available for their identification and susceptibility testing. Since their susceptibility varies with species, it becomes imperative to perform drug susceptibility testing. Various methods are available, of which broth microdilution is recommended by the Clinical and Laboratory Standards Institute (CLSI). We report our results after using RAPMYCO, commercially available, predosed, ready-to-use broth-microdilution plate. Materials and Methods: A total of 33 isolates of NTM were tested using the RAPMYCO panel for susceptibility against amikacin, cefoxitin, ciprofloxacin, clarithromycin, doxycycline, imipenem, linezolid, trimethoprim + sulfamethoxazole, tobramycin, and tigecycline, and the results were interpreted as per the CLSI guidelines. Results and Conclusion: Minimum inhibitory concentration results of conventional broth microdilution correlated well with those of RAPMYCO. All Mycobacterium fortuitum and Mycobacterium chelonae isolates were susceptible to amikacin and tobramycin.Good susceptibility was observed towards clarithromycin for all isolates; some degree of susceptibility was observed for quinolones and linezolid. High degree of resistance was seen for cefoxitin, doxycycline, and trimethoprim + sulfamethoxazole. Mycobacterium abscessus was the most resistant. RAPMYCO was simple, easy, and saved precious person-hours as compared to conventional broth microdilution.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"36 1","pages":"93 - 97"},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83149768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Narayana Goruntla, GovardhanKumar Arakala, GowthamiPriyanka Nelluri, K. Mounika, S. Pujari, ManojKumar Byalla
Aims: The aims of this study were to: (1) Comparison of Psoriasis Area Severity Index (PASI), Physician Global Assessment (PGA) Scores, and adverse effect profile on the use of topical salicylic acid 6% versus clobetasol propionate 0.05% in the chronic-limited plaque psoriasis.(2) Selection of the cost-effectiveness option using average cost-effective ratios of the two individual regimens. Materials and Methods: This was a randomized, open-labeled, parallel group design which was conducted at dermatology department of a tertiary care hospital located in resource-limited settings of South India. A total of 75 patients were recruited and randomized into two groups: Group A received 6% of topical salicylic acid and Group B received 0.05% of clobetasol propionate for 3 months with a three follow-up visits. Efficacy was assessed based on the reduction of PASI and PGA scores at each visit. The safety profile of two drugs was assessed by a screening of adverse drug reactions. Cost-effectiveness of treatment groups was calculated by considering inputs of direct medical costs required to reduce one unit on PGA scale. Results: Demographic and clinical profiles of participants were matched between two groups. The mean PASI score of Group A and Group B were reduced from baseline (4.36, 4.67) to final follow-up (1.97, 2.03). There was a statistically significant difference exist in mean PASI score difference of Group A and Group B from baseline to 1st follow-up and baseline to 2nd follow-up (P < 0.00001) visits. Whereas, at final follow-up, mean PASI score difference of two groups was almost equal (P < 0.21). Conclusion: Initially, clobetasol propionate shows more effective compared to salicylic acid in the reduction of PASI score. But at end of the treatment, both drugs were equal in the reduction of PASI score where only matters the cost. Salicylic acid was a cost-effectiveness option in limited chronic plaque psoriasis.
{"title":"Comparison of efficacy, safety, and cost-effectiveness of topical salicylic acid 6% versus clobetasol propionate 0.05% in the treatment of limited chronic plaque psoriasis","authors":"Narayana Goruntla, GovardhanKumar Arakala, GowthamiPriyanka Nelluri, K. Mounika, S. Pujari, ManojKumar Byalla","doi":"10.4103/JHRR.JHRR_3_18","DOIUrl":"https://doi.org/10.4103/JHRR.JHRR_3_18","url":null,"abstract":"Aims: The aims of this study were to: (1) Comparison of Psoriasis Area Severity Index (PASI), Physician Global Assessment (PGA) Scores, and adverse effect profile on the use of topical salicylic acid 6% versus clobetasol propionate 0.05% in the chronic-limited plaque psoriasis.(2) Selection of the cost-effectiveness option using average cost-effective ratios of the two individual regimens. Materials and Methods: This was a randomized, open-labeled, parallel group design which was conducted at dermatology department of a tertiary care hospital located in resource-limited settings of South India. A total of 75 patients were recruited and randomized into two groups: Group A received 6% of topical salicylic acid and Group B received 0.05% of clobetasol propionate for 3 months with a three follow-up visits. Efficacy was assessed based on the reduction of PASI and PGA scores at each visit. The safety profile of two drugs was assessed by a screening of adverse drug reactions. Cost-effectiveness of treatment groups was calculated by considering inputs of direct medical costs required to reduce one unit on PGA scale. Results: Demographic and clinical profiles of participants were matched between two groups. The mean PASI score of Group A and Group B were reduced from baseline (4.36, 4.67) to final follow-up (1.97, 2.03). There was a statistically significant difference exist in mean PASI score difference of Group A and Group B from baseline to 1st follow-up and baseline to 2nd follow-up (P < 0.00001) visits. Whereas, at final follow-up, mean PASI score difference of two groups was almost equal (P < 0.21). Conclusion: Initially, clobetasol propionate shows more effective compared to salicylic acid in the reduction of PASI score. But at end of the treatment, both drugs were equal in the reduction of PASI score where only matters the cost. Salicylic acid was a cost-effectiveness option in limited chronic plaque psoriasis.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"528 1","pages":"86 - 92"},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88948836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: The study was aimed at describing the epidemiology of hypoglycemia among ambulatory type 2 diabetic patients in a primary care clinic in Eastern Nigeria. Materials and Methods: A cross-sectional descriptive study was carried out on 145 type 2 diabetic patients in a primary care clinic in Nigeria. Data were collected using pretested, structured, and interviewer-administered questionnaire containing information on relevant epidemiological variables. Experience of hypoglycemia was defined as self-reported symptoms of hypoglycemia in the previous 1 year. Results: The age of type 2 diabetic patients ranged from 32 to 78 years with mean age of 44 ± 10.2 years. There were 59 (40.7%) males and 86 (59.3%) females. The prevalence of hypoglycemia was 35.2%. Hypoglycemia occurred predominantly among the elderly (72.5%), male gender (54.9%), outside home environment (72.5%), during the daytime (82.4%), duration of diabetes ≤1 year (58.8%), and patients on insulin secretagogues alone (46.2%). The most common symptom was dizziness (76.5%). Experience of hypoglycemia was significantly associated with elderly age (P = 0.025), duration of diabetes ≤1 year (P = 0.021), and use of insulin secretagogues alone (P = 0.043). The most significant predictor of hypoglycemic events was use of insulin and insulin secretagogues (odds ratio = 3.15 [1.74–5.66]; P = 0.002). Type 2 diabetic patients on insulin and insulin secretagogues were three times more likely to experience hypoglycemic events compared to their counterparts who were on insulin sensitizers. Conclusion: The study has shown variable epidemiology of hypoglycemia. The incident occurred predominantly among the elderly, male gender, during daytime, outside home environment, duration of diabetes ≤1 year, and patients on insulin and insulin secretagogues. Interventional measures for hypoglycemia should consider relevant epidemiological factors that predispose to hypoglycemia.
{"title":"Epidemiology of hypoglycemia among ambulatory Type 2 diabetic patients in a primary care clinic of a tertiary hospital in Southeastern Nigeria","authors":"G. Iloh, A. Amadi","doi":"10.4103/JHRR.JHRR_37_17","DOIUrl":"https://doi.org/10.4103/JHRR.JHRR_37_17","url":null,"abstract":"Aim: The study was aimed at describing the epidemiology of hypoglycemia among ambulatory type 2 diabetic patients in a primary care clinic in Eastern Nigeria. Materials and Methods: A cross-sectional descriptive study was carried out on 145 type 2 diabetic patients in a primary care clinic in Nigeria. Data were collected using pretested, structured, and interviewer-administered questionnaire containing information on relevant epidemiological variables. Experience of hypoglycemia was defined as self-reported symptoms of hypoglycemia in the previous 1 year. Results: The age of type 2 diabetic patients ranged from 32 to 78 years with mean age of 44 ± 10.2 years. There were 59 (40.7%) males and 86 (59.3%) females. The prevalence of hypoglycemia was 35.2%. Hypoglycemia occurred predominantly among the elderly (72.5%), male gender (54.9%), outside home environment (72.5%), during the daytime (82.4%), duration of diabetes ≤1 year (58.8%), and patients on insulin secretagogues alone (46.2%). The most common symptom was dizziness (76.5%). Experience of hypoglycemia was significantly associated with elderly age (P = 0.025), duration of diabetes ≤1 year (P = 0.021), and use of insulin secretagogues alone (P = 0.043). The most significant predictor of hypoglycemic events was use of insulin and insulin secretagogues (odds ratio = 3.15 [1.74–5.66]; P = 0.002). Type 2 diabetic patients on insulin and insulin secretagogues were three times more likely to experience hypoglycemic events compared to their counterparts who were on insulin sensitizers. Conclusion: The study has shown variable epidemiology of hypoglycemia. The incident occurred predominantly among the elderly, male gender, during daytime, outside home environment, duration of diabetes ≤1 year, and patients on insulin and insulin secretagogues. Interventional measures for hypoglycemia should consider relevant epidemiological factors that predispose to hypoglycemia.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"35 1","pages":"57 - 65"},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90283647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Enteric parasitic diseases pose a serious public health problem worldwide and yet are neglected. To refocus attention on these diseases, a cross-sectional study was conducted to assess the prevalence of enteric infections in patients referred to referral hospital in Kenya. Materials and Methods: This study was conducted from April to December 2015 and involved a randomly selected sample of 185 patients. Fecal specimens were collected and delivered to laboratory for analysis. Preliminary macroscopic assessment of specimens for segments, larvae, and adult stages was done. To confirm the presence of ova, trophozoites, cysts, and oocysts, direct wet smear, formol–ether concentration, and modified Ziehl–Neelsen techniques were used. Results: Overall prevalence of 46.5% of enteric parasitic diseases was confirmed. Highest and lowest prevalence was due to protozoans and helminthes, respectively. Protozoan parasite prevalence was Entamoeba histolytica (23.9%), Cryptosporidium parvum (13%), Entamoeba coli (6.5%), Giardia lamblia (6.5%), and Iodamoeba butschlii (6.5%). Helminth prevalence was Ascaris lumbricoides (1.6%), Hymenolepis nana, Trichuris trichiura, and Ancylostoma duodenale each (0.5%). There was no significant difference in prevalence in age groups and gender (P = 0.05). Females were at the highest risk of C. parvum infection. Polyparasitism was prevalent among protozoans than helminthes. Conclusion: High prevalence of protozoan infections was observed among referred patients in comparison to helminthiasis. Based on reported multiple infections, deworming programs targeting helminthiasis should be restructured to incorporate diagnosis and treatment of enteric protozoan infections to reduce prevalence of enteric parasitic infections.
{"title":"Prevalence of enteric parasitic diseases among patients referred at a teaching hospital in Kenya","authors":"Rose Jepkosgei Kimosop, C. Mulambalah, M. Ngeiywa","doi":"10.4103/JHRR.JHRR_7_18","DOIUrl":"https://doi.org/10.4103/JHRR.JHRR_7_18","url":null,"abstract":"Aim: Enteric parasitic diseases pose a serious public health problem worldwide and yet are neglected. To refocus attention on these diseases, a cross-sectional study was conducted to assess the prevalence of enteric infections in patients referred to referral hospital in Kenya. Materials and Methods: This study was conducted from April to December 2015 and involved a randomly selected sample of 185 patients. Fecal specimens were collected and delivered to laboratory for analysis. Preliminary macroscopic assessment of specimens for segments, larvae, and adult stages was done. To confirm the presence of ova, trophozoites, cysts, and oocysts, direct wet smear, formol–ether concentration, and modified Ziehl–Neelsen techniques were used. Results: Overall prevalence of 46.5% of enteric parasitic diseases was confirmed. Highest and lowest prevalence was due to protozoans and helminthes, respectively. Protozoan parasite prevalence was Entamoeba histolytica (23.9%), Cryptosporidium parvum (13%), Entamoeba coli (6.5%), Giardia lamblia (6.5%), and Iodamoeba butschlii (6.5%). Helminth prevalence was Ascaris lumbricoides (1.6%), Hymenolepis nana, Trichuris trichiura, and Ancylostoma duodenale each (0.5%). There was no significant difference in prevalence in age groups and gender (P = 0.05). Females were at the highest risk of C. parvum infection. Polyparasitism was prevalent among protozoans than helminthes. Conclusion: High prevalence of protozoan infections was observed among referred patients in comparison to helminthiasis. Based on reported multiple infections, deworming programs targeting helminthiasis should be restructured to incorporate diagnosis and treatment of enteric protozoan infections to reduce prevalence of enteric parasitic infections.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"15 1","pages":"78 - 85"},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85929262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-05-01DOI: 10.4103/JHRR.JHRR_121_16
G. Iloh, A. Amadi
Aim: The study was aimed at determining the role of family support in medication adherence and glycemic control among ambulatory Type 2 diabetic patients in a primary care clinic in Nigeria. Materials and Methods: A clinic-based descriptive study was done on 120 Type 2 diabetic Nigerians who were on treatment for at least 3 months at the primary care clinic in Nigeria. Family support and medication adherence were assessed in the previous 3 months and 1 month preceding the study using multi-dimensional Scale of Perceived Social Support and interviewer-administered questionnaire on self-administered and reported therapy (SAT), respectively. Glycemic control was assessed in the previous 1 month. Results: The age of the participants ranged from 27 to 81 years, and there were 37.5% males and 62.5% females with sex ratio of 1:1.7. Family support, medication adherence, and glycemic control rates were 77.5%, 72.5%, and 61.7%, respectively. Family support was significantly associated with elderly age (0.041), medication adherence (P = 0.038), and glycemic control (P = 0.027). The most significant demographic predictor of family support was elderly age (odds ratio = 4.30 [2.06–5.15]; P = 0.015). The elderly patients with Type 2 diabetes were four times more likely to have family support compared to their counterparts who were <60 years. Conclusion: This study has shown the level of family support, medication adherence, and glycemic control among patients with Type 2 diabetes. Family support was significantly associated with elderly age, medication adherence, and glycemic control. Interventions to improve medication adherence and glycemic control should consider measures to enhance family support and this could be used to plan diabetes-oriented management decisions.
{"title":"Family support, medication adherence andglycaemic control among ambulatory type 2 diabetic Nigerians in a primary care clinic in Eastern Nigeria","authors":"G. Iloh, A. Amadi","doi":"10.4103/JHRR.JHRR_121_16","DOIUrl":"https://doi.org/10.4103/JHRR.JHRR_121_16","url":null,"abstract":"Aim: The study was aimed at determining the role of family support in medication adherence and glycemic control among ambulatory Type 2 diabetic patients in a primary care clinic in Nigeria. Materials and Methods: A clinic-based descriptive study was done on 120 Type 2 diabetic Nigerians who were on treatment for at least 3 months at the primary care clinic in Nigeria. Family support and medication adherence were assessed in the previous 3 months and 1 month preceding the study using multi-dimensional Scale of Perceived Social Support and interviewer-administered questionnaire on self-administered and reported therapy (SAT), respectively. Glycemic control was assessed in the previous 1 month. Results: The age of the participants ranged from 27 to 81 years, and there were 37.5% males and 62.5% females with sex ratio of 1:1.7. Family support, medication adherence, and glycemic control rates were 77.5%, 72.5%, and 61.7%, respectively. Family support was significantly associated with elderly age (0.041), medication adherence (P = 0.038), and glycemic control (P = 0.027). The most significant demographic predictor of family support was elderly age (odds ratio = 4.30 [2.06–5.15]; P = 0.015). The elderly patients with Type 2 diabetes were four times more likely to have family support compared to their counterparts who were <60 years. Conclusion: This study has shown the level of family support, medication adherence, and glycemic control among patients with Type 2 diabetes. Family support was significantly associated with elderly age, medication adherence, and glycemic control. Interventions to improve medication adherence and glycemic control should consider measures to enhance family support and this could be used to plan diabetes-oriented management decisions.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"115 1","pages":"71 - 77"},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76873695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Snakebite envenoming causes considerable morbidity and mortality in rural, agrarian, and poor-resourced communities of Sub-Saharan Africa and Asia. Echis ocellatus (carpet viper) is responsible for most injuries and deaths in Northern Nigeria. Tissue necrosis and hemorrhage are the key features of this snake species. While bleeding can occur into virtually any tissue of the body following snakebite envenoming, sublingual hematoma (SLH) has been scarcely reported. The index patient was an adult female farmer with delayed presentation of SLH following venomous snakebite in a rural Nigerian community. Diagnostic and management challenges were encountered.
{"title":"Sublingual hematoma following viper envenoming","authors":"G. Michael, I. Aliyu, B. Grema","doi":"10.4103/JHRR.JHRR_20_18","DOIUrl":"https://doi.org/10.4103/JHRR.JHRR_20_18","url":null,"abstract":"Snakebite envenoming causes considerable morbidity and mortality in rural, agrarian, and poor-resourced communities of Sub-Saharan Africa and Asia. Echis ocellatus (carpet viper) is responsible for most injuries and deaths in Northern Nigeria. Tissue necrosis and hemorrhage are the key features of this snake species. While bleeding can occur into virtually any tissue of the body following snakebite envenoming, sublingual hematoma (SLH) has been scarcely reported. The index patient was an adult female farmer with delayed presentation of SLH following venomous snakebite in a rural Nigerian community. Diagnostic and management challenges were encountered.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"134 1","pages":"108 - 110"},"PeriodicalIF":0.0,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88901230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4103/JHRR.JHRR_104_17
O. Fasipe, Oluwatosin Beatrice Ibiyemi, A. Adelosoye, Ayodeji Idowu
Estrogen deficiency (most especially low level of β-estradiol isoform) is the major contributing factor to bone loss after menopause. Supplementation with calcium and Vitamin D is an essential baseline therapy for osteoporosis prevention and treatment. Newer emerging agents that will further expand osteoporosis therapeutic options include strontium compound (a bone selective calcium-sensing receptor [CaSR] agonist or calcimimetic which is currently licensed for use in Europe but not in the US that has both osteoanabolic and antiresorptive activity); Lasofoxifene (a new selective estrogen receptor modulator [SERM] or estrogen agonist-antagonist [EAA] with partial agonist activity at both estrogen receptors ERα and ERβ); odanacatib and balicatib (inhibitors of the resorptive enzyme cathepsin K); abaloparatide (a parathyroid hormone [PTH]-related protein analog); ostabolin-C (a new cyclicised PTH analog); romosozumab and blosozumab (monoclonal antibody inhibitors to sclerostin) which are currently undergoing clinical trial for Food and Drug Administration approval. Other agents in preclinical development include anti-dickkopf antibody (BHQ880) which targets specific protein molecules of the Wnt/β-catenin pathway involved in stimulating new bone formation by osteoblast cells; parathyroid selective short-acting calcium-sensing receptor antagonists or calcilytics (SB-423562, SB-423557, JTT-305/MK-5442, and NPS-2143) that will lead to a transient release of PTH from the parathyroid glands; and saracatinib (a novel orally available competitive inhibitor of the enzyme Src kinase and Abl kinase family shown to inhibit osteoclast-mediated bone resorption). This review article discusses these newer evolving agents that will introduce and incorporate remarkable improvements into the management of postmenopausal osteoporosis in the nearer future.
{"title":"Recent advances and current trend in the pharmacotherapy of postmenopausal osteoporosis","authors":"O. Fasipe, Oluwatosin Beatrice Ibiyemi, A. Adelosoye, Ayodeji Idowu","doi":"10.4103/JHRR.JHRR_104_17","DOIUrl":"https://doi.org/10.4103/JHRR.JHRR_104_17","url":null,"abstract":"Estrogen deficiency (most especially low level of β-estradiol isoform) is the major contributing factor to bone loss after menopause. Supplementation with calcium and Vitamin D is an essential baseline therapy for osteoporosis prevention and treatment. Newer emerging agents that will further expand osteoporosis therapeutic options include strontium compound (a bone selective calcium-sensing receptor [CaSR] agonist or calcimimetic which is currently licensed for use in Europe but not in the US that has both osteoanabolic and antiresorptive activity); Lasofoxifene (a new selective estrogen receptor modulator [SERM] or estrogen agonist-antagonist [EAA] with partial agonist activity at both estrogen receptors ERα and ERβ); odanacatib and balicatib (inhibitors of the resorptive enzyme cathepsin K); abaloparatide (a parathyroid hormone [PTH]-related protein analog); ostabolin-C (a new cyclicised PTH analog); romosozumab and blosozumab (monoclonal antibody inhibitors to sclerostin) which are currently undergoing clinical trial for Food and Drug Administration approval. Other agents in preclinical development include anti-dickkopf antibody (BHQ880) which targets specific protein molecules of the Wnt/β-catenin pathway involved in stimulating new bone formation by osteoblast cells; parathyroid selective short-acting calcium-sensing receptor antagonists or calcilytics (SB-423562, SB-423557, JTT-305/MK-5442, and NPS-2143) that will lead to a transient release of PTH from the parathyroid glands; and saracatinib (a novel orally available competitive inhibitor of the enzyme Src kinase and Abl kinase family shown to inhibit osteoclast-mediated bone resorption). This review article discusses these newer evolving agents that will introduce and incorporate remarkable improvements into the management of postmenopausal osteoporosis in the nearer future.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"22 1","pages":"13 - 21"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78844519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Adoga, N. Ma’an, A. Adekwu, A. Kodiya, O. Nwaorgu, K. Ozoilo
Aim: This study is designed to evaluate the challenges of residency training in otolaryngology in Nigeria from the point of view of the trainees. Materials and Methods: The study setting was the 2014 otolaryngology revision/update course organized by the West African College of Surgeons at University College Hospital, Ibadan. This was a questionnaire-based study administered to 78 resident doctors from different training institutions across the country who participated in the revision course. All participants consented to the study and were given a structured questionnaire to complete and return. Data were collated in Microsoft Excel® spreadsheet and analyzed using Epi Info® 2002 Epidemiology program Office Centre for disease Control, Atlanta USA. Results: Seventy-six out of the 78 residents who attended the course responded, giving a response rate of 97.4%. The geographical distribution showed that the South West had 5 (27.8%) institutions, while North East and South East had 1 (5.6%) and 2 (11.1%), respectively. Fifty-six (73.7%) of the respondents were under 40 years of age. The gender ratio was 4.7:1. Sixty-eight (89.5%) were married. The decision to choose ORL was personal interest in 68 (89.5%). Textbooks were available to 45 (59.2%) respondents. Thirty (39.5%) of them read for at least 2 h/day, and obstacles to reading were clinical work overload in 56 (73.7%) and fatigue in 55 (72.4%). Forty (52.6%) respondents had >5 consultant Ear-Nose-Throat surgeons in their institutions. Departmental activities were also highlighted. Conclusion: This study highlighted the location of majority of the ORL residency training institutions in South West, Nigeria, and married. Most of the respondents have the required textbooks but found it hard to read mainly due to clinical work overload and family burden.
{"title":"Otorhinolaryngology postgraduate training in Nigeria: Trainees perspective","authors":"S. Adoga, N. Ma’an, A. Adekwu, A. Kodiya, O. Nwaorgu, K. Ozoilo","doi":"10.4103/JHRR.JHRR_50_17","DOIUrl":"https://doi.org/10.4103/JHRR.JHRR_50_17","url":null,"abstract":"Aim: This study is designed to evaluate the challenges of residency training in otolaryngology in Nigeria from the point of view of the trainees. Materials and Methods: The study setting was the 2014 otolaryngology revision/update course organized by the West African College of Surgeons at University College Hospital, Ibadan. This was a questionnaire-based study administered to 78 resident doctors from different training institutions across the country who participated in the revision course. All participants consented to the study and were given a structured questionnaire to complete and return. Data were collated in Microsoft Excel® spreadsheet and analyzed using Epi Info® 2002 Epidemiology program Office Centre for disease Control, Atlanta USA. Results: Seventy-six out of the 78 residents who attended the course responded, giving a response rate of 97.4%. The geographical distribution showed that the South West had 5 (27.8%) institutions, while North East and South East had 1 (5.6%) and 2 (11.1%), respectively. Fifty-six (73.7%) of the respondents were under 40 years of age. The gender ratio was 4.7:1. Sixty-eight (89.5%) were married. The decision to choose ORL was personal interest in 68 (89.5%). Textbooks were available to 45 (59.2%) respondents. Thirty (39.5%) of them read for at least 2 h/day, and obstacles to reading were clinical work overload in 56 (73.7%) and fatigue in 55 (72.4%). Forty (52.6%) respondents had >5 consultant Ear-Nose-Throat surgeons in their institutions. Departmental activities were also highlighted. Conclusion: This study highlighted the location of majority of the ORL residency training institutions in South West, Nigeria, and married. Most of the respondents have the required textbooks but found it hard to read mainly due to clinical work overload and family burden.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"5 1","pages":"48 - 56"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85207846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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