G. Duarte, I. Felberg, V. Calado, J. DePaula, Monalisa S. C. de Jesus, R. Deliza, Marco Antonio L. Miguel, A. Farah
This study aimed at developing a probiotic fermented soymilk-based dessert containing coffee and soybean hull. Nine fermented formulations were elaborated with 10% powdered soymilk (w/v), varying percentages of sugar, arabica soluble coffee, and soy hull. They were fermented with probiotic strains of Lactobacilli and Bifidobacteria (10 6 CFU/mL). One hundred and twenty-nine adults from Rio de Janeiro/RJ and Curitiba/PR, Brazil, evaluated the acceptance of the formulated products. The final formulation was physicochemically characterized. During 6h fermentation, the probiotics count increased from 10 6 to 10 8 in both strains. The well-accepted formulation contained 15% sucrose, 1% soy hull, and 0.5 or 1.5 % soluble coffee (score: 6.6±1.5 on a 9-point-scale). Alternatively, sucrose can be replaced by other types of sweeteners. Young people (n=45) who drank 2-4 cups of coffee per day liked the product the most (score: 7.1±1.4). While fermentation did not affect the total soy isoflavones content, it decreased the content of coffee chlorogenic acids by 32.6% but produced bioavailable phenolic acids as metabolites. A decrease in the content of flatus-producing oligosaccharides was also observed. In conclusion, probiotics fermentation and the addition of arabica soluble coffee made possible the development of a well-accepted and potentially healthy beany-flavor-free, dairy-free, pudding-like dessert.
{"title":"Fermented Soy-coffee Pudding Dessert Containing Probiotics: Product Formulation and Evaluation of Compositional Changes during Fermentation","authors":"G. Duarte, I. Felberg, V. Calado, J. DePaula, Monalisa S. C. de Jesus, R. Deliza, Marco Antonio L. Miguel, A. Farah","doi":"10.12691/jfnr-11-5-1","DOIUrl":"https://doi.org/10.12691/jfnr-11-5-1","url":null,"abstract":"This study aimed at developing a probiotic fermented soymilk-based dessert containing coffee and soybean hull. Nine fermented formulations were elaborated with 10% powdered soymilk (w/v), varying percentages of sugar, arabica soluble coffee, and soy hull. They were fermented with probiotic strains of Lactobacilli and Bifidobacteria (10 6 CFU/mL). One hundred and twenty-nine adults from Rio de Janeiro/RJ and Curitiba/PR, Brazil, evaluated the acceptance of the formulated products. The final formulation was physicochemically characterized. During 6h fermentation, the probiotics count increased from 10 6 to 10 8 in both strains. The well-accepted formulation contained 15% sucrose, 1% soy hull, and 0.5 or 1.5 % soluble coffee (score: 6.6±1.5 on a 9-point-scale). Alternatively, sucrose can be replaced by other types of sweeteners. Young people (n=45) who drank 2-4 cups of coffee per day liked the product the most (score: 7.1±1.4). While fermentation did not affect the total soy isoflavones content, it decreased the content of coffee chlorogenic acids by 32.6% but produced bioavailable phenolic acids as metabolites. A decrease in the content of flatus-producing oligosaccharides was also observed. In conclusion, probiotics fermentation and the addition of arabica soluble coffee made possible the development of a well-accepted and potentially healthy beany-flavor-free, dairy-free, pudding-like dessert.","PeriodicalId":16096,"journal":{"name":"Journal of Food and Nutrition Research","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46104239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this study was to evaluate if Metabolic® Ultra, a nutraceutical containing Chitosan and α-Lipoic acid (Nutraceutical), can decrease anthropometric measures and ameliorate metabolic values, inflammatory status, and cytokine parameters in patients with obesity. We enrolled 60 Caucasian obese (BMI ≥ 30 kg/m 2 ) nondiabetic patients, aged ≥ 18 of either sex. Patients were randomized to take placebo or Nutraceutical for 6 months, in a randomized, double-blind, placebo-controlled design. Nutraceutical and placebo were self-administered twice a day, 3 tablets fifteen minutes before lunch and dinner. A significant decrease of weight, BMI, and Abd. Cir. were observed after 6 months of Nutraceutical treatment (p< 0.05 vs Baseline) compared to placebo. No Waist Cir. and Hip Cir. variations were observed in both groups. No variation of FPG, FPI, and Homa index were recorded in both groups compared to Baseline. A significant TC, LDL-C, and Tg decrease was recorded at 6 months in the Nutraceutical group compared to the placebo group (p< 0.05 vs Baseline, respectively), and a significant TC, and LDL-C decrease was found at 6 months compared to placebo group (p< 0.05, respectively). No significant HDL-C variation was observed in the Nutraceutical group, although there was an increasing trend. High-sensitivity C-reactive protein was significantly reduced at 6 months in the Nutraceutical group (p< 0.05 vs Baseline, and p< 0.05 vs placebo), while the ADN was raised to 6 months in the Nutraceutical group (p< 0.05 vs Baseline, and p< 0.05 vs placebo). No significant change was seen for IL-6 and TNF-α at the end of the study in both treatments. All the patients who finished the study and underwent OGTT at Baseline and after 6 months were euglycemic at the end of the second hour in both groups. We can conclude that a nutraceutical containing Chitosan and α-Lipoic acid can be helpful in reducing weight and BMI, in improving lipid profile, and in reducing inflammatory parameters, without affecting the glycemic status of obese patients.
{"title":"Nutraceutical Supplementation in Obese Patients and Effects on Anthropometric, Metabolic, and Inflammatory Parameters","authors":"G. Derosa, A. D'Angelo, P. Maffioli","doi":"10.12691/jfnr-11-5-3","DOIUrl":"https://doi.org/10.12691/jfnr-11-5-3","url":null,"abstract":"The aim of this study was to evaluate if Metabolic® Ultra, a nutraceutical containing Chitosan and α-Lipoic acid (Nutraceutical), can decrease anthropometric measures and ameliorate metabolic values, inflammatory status, and cytokine parameters in patients with obesity. We enrolled 60 Caucasian obese (BMI ≥ 30 kg/m 2 ) nondiabetic patients, aged ≥ 18 of either sex. Patients were randomized to take placebo or Nutraceutical for 6 months, in a randomized, double-blind, placebo-controlled design. Nutraceutical and placebo were self-administered twice a day, 3 tablets fifteen minutes before lunch and dinner. A significant decrease of weight, BMI, and Abd. Cir. were observed after 6 months of Nutraceutical treatment (p< 0.05 vs Baseline) compared to placebo. No Waist Cir. and Hip Cir. variations were observed in both groups. No variation of FPG, FPI, and Homa index were recorded in both groups compared to Baseline. A significant TC, LDL-C, and Tg decrease was recorded at 6 months in the Nutraceutical group compared to the placebo group (p< 0.05 vs Baseline, respectively), and a significant TC, and LDL-C decrease was found at 6 months compared to placebo group (p< 0.05, respectively). No significant HDL-C variation was observed in the Nutraceutical group, although there was an increasing trend. High-sensitivity C-reactive protein was significantly reduced at 6 months in the Nutraceutical group (p< 0.05 vs Baseline, and p< 0.05 vs placebo), while the ADN was raised to 6 months in the Nutraceutical group (p< 0.05 vs Baseline, and p< 0.05 vs placebo). No significant change was seen for IL-6 and TNF-α at the end of the study in both treatments. All the patients who finished the study and underwent OGTT at Baseline and after 6 months were euglycemic at the end of the second hour in both groups. We can conclude that a nutraceutical containing Chitosan and α-Lipoic acid can be helpful in reducing weight and BMI, in improving lipid profile, and in reducing inflammatory parameters, without affecting the glycemic status of obese patients.","PeriodicalId":16096,"journal":{"name":"Journal of Food and Nutrition Research","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45284596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Doaa E. El-Hadedy, Nesreen A. Safwat, Abir Pertila, Rafat A. Siddiqui
In the food industry, alkaline protease plays an important role in the formation of value-added products. Alkaline protease also plays a significant role in waste management. In this study, to construct a stable and high-yield alkaline protease producer, we investigated a combined strategy of gamma radiation as an enhancement factor and alkaline protease PGEM-T easy construct . The present study was focused on the isolation of the sprA gene-producing alkaline protease from Streptomyces flavogriseus ADEM7 (AB723783.1). Optimum growth media, fermentation conditions, and proteolytic activity assay were evaluated. The result showed that the free cells preparation produced alkaline protease with a specific activity of 550 U/mg after being exposed to gamma radiation at 10 KGy. The sprA gene was detected using polymerase chain reaction followed by cloning in PGEM-T easy vector, transformation in E. coli JM109, and direct construct sequencing. The s prA gene encoding streptogrisin a (alkaline protease-like activity) was isolated in this study and recorded in the gene bank with accession number AB827411.1. The extracellular protease enzyme was tested for antioxidant and anticancer activities. In future work, we will extract this alkaline protease from the same strain on a larger scale using a fermenter and will characterize its antioxidant activity under in vivo conditions.
{"title":"Isolation and Cloning of sprA Gene Alkaline Protease Activity from Streptomyces flavogriseus ADEM7 and Characterization of Its Antioxidant and Antitumor Activities","authors":"Doaa E. El-Hadedy, Nesreen A. Safwat, Abir Pertila, Rafat A. Siddiqui","doi":"10.12691/jfnr-11-5-2","DOIUrl":"https://doi.org/10.12691/jfnr-11-5-2","url":null,"abstract":"In the food industry, alkaline protease plays an important role in the formation of value-added products. Alkaline protease also plays a significant role in waste management. In this study, to construct a stable and high-yield alkaline protease producer, we investigated a combined strategy of gamma radiation as an enhancement factor and alkaline protease PGEM-T easy construct . The present study was focused on the isolation of the sprA gene-producing alkaline protease from Streptomyces flavogriseus ADEM7 (AB723783.1). Optimum growth media, fermentation conditions, and proteolytic activity assay were evaluated. The result showed that the free cells preparation produced alkaline protease with a specific activity of 550 U/mg after being exposed to gamma radiation at 10 KGy. The sprA gene was detected using polymerase chain reaction followed by cloning in PGEM-T easy vector, transformation in E. coli JM109, and direct construct sequencing. The s prA gene encoding streptogrisin a (alkaline protease-like activity) was isolated in this study and recorded in the gene bank with accession number AB827411.1. The extracellular protease enzyme was tested for antioxidant and anticancer activities. In future work, we will extract this alkaline protease from the same strain on a larger scale using a fermenter and will characterize its antioxidant activity under in vivo conditions.","PeriodicalId":16096,"journal":{"name":"Journal of Food and Nutrition Research","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47861437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ma. Guadalupe Garnica-Romo, Diana Cecilia Maya-Cortés, Juan de Dios Figueroa Cárdenas, José Juan Véles-Medina, Rafael Zamora-Vega, Héctor Eduardo Martínez-Flores
{"title":"Physicochemical, Mechanical, and Structural Properties of the Femur from Rats Fed with Corn Tortillas (Zea mays L.) Prepared with Calcium Sulfate","authors":"Ma. Guadalupe Garnica-Romo, Diana Cecilia Maya-Cortés, Juan de Dios Figueroa Cárdenas, José Juan Véles-Medina, Rafael Zamora-Vega, Héctor Eduardo Martínez-Flores","doi":"10.12691/jfnr-11-4-7","DOIUrl":"https://doi.org/10.12691/jfnr-11-4-7","url":null,"abstract":"","PeriodicalId":16096,"journal":{"name":"Journal of Food and Nutrition Research","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44135883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The primary endpoint of the current study was to evaluate whether the effects previously demonstrated in the 3-month study could be maintained for 12 months. Patients were randomized to take Glicoset® in addition to a standardized diet, or to follow a standardized diet alone for 12 months. Glicoset® was self-administered once a day, 1 tablet during the breakfast. After 12 months, 31.9 % of patients retuned to a normal glycemic status in the group treated with nutraceutical + diet vs 3.3 % of patients in diet alone group (p < 0.05). At the end of the study 43.6% were classified as IFG in the group treated with nutraceutical + diet group vs 37% in diet alone group (p < 0.05). In the group treated with nutraceutical + diet, 24.5% were classified as IGT at the end of the study vs 51.1% in diet alone group (p < 0.01). In diet alone group, 8.7% developed type 2 diabetes mellitus vs 0 patients in diet + nutraceutical group (p < 0.05). Total cholesterol, LDL-C, and Tg were lower in the group treated with the nutraceutical combination. The positive effects on glycemic and lipid profile already showed in a 3 months study were also maintained after 12 months of treatment with a nutraceutical containing Ilex Paraguariensis, White Mulberry and Chromium Picolinate.
{"title":"Effects on Glyco-Metabolic Control after 12 Months of Treatment with a Supplement of Ilex Paraguariensis, White Mulberry and Chromium Picolinate in Non-Diabetic Patients with Dysglycemia","authors":"G. Derosa, A. D'Angelo, P. Maffioli","doi":"10.12691/jfnr-11-4-6","DOIUrl":"https://doi.org/10.12691/jfnr-11-4-6","url":null,"abstract":"The primary endpoint of the current study was to evaluate whether the effects previously demonstrated in the 3-month study could be maintained for 12 months. Patients were randomized to take Glicoset® in addition to a standardized diet, or to follow a standardized diet alone for 12 months. Glicoset® was self-administered once a day, 1 tablet during the breakfast. After 12 months, 31.9 % of patients retuned to a normal glycemic status in the group treated with nutraceutical + diet vs 3.3 % of patients in diet alone group (p < 0.05). At the end of the study 43.6% were classified as IFG in the group treated with nutraceutical + diet group vs 37% in diet alone group (p < 0.05). In the group treated with nutraceutical + diet, 24.5% were classified as IGT at the end of the study vs 51.1% in diet alone group (p < 0.01). In diet alone group, 8.7% developed type 2 diabetes mellitus vs 0 patients in diet + nutraceutical group (p < 0.05). Total cholesterol, LDL-C, and Tg were lower in the group treated with the nutraceutical combination. The positive effects on glycemic and lipid profile already showed in a 3 months study were also maintained after 12 months of treatment with a nutraceutical containing Ilex Paraguariensis, White Mulberry and Chromium Picolinate.","PeriodicalId":16096,"journal":{"name":"Journal of Food and Nutrition Research","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43780068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genome-wide Association Functional Studies (GWAFS) of Candidate Genes for Germination-related Traits of Low Temperature Tolerance in Maize (Zea mays L.)","authors":"Lin Heying, Ren Zhiqiang, H. Noor","doi":"10.12691/jfnr-11-4-5","DOIUrl":"https://doi.org/10.12691/jfnr-11-4-5","url":null,"abstract":"","PeriodicalId":16096,"journal":{"name":"Journal of Food and Nutrition Research","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44963591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of Genetic Diversity and Construction Fingerprint of Protein Content of Quinoa (Chenopodium quinoa Willd.) Vegetable Leaf","authors":"","doi":"10.12691/jfnr-11-4-3","DOIUrl":"https://doi.org/10.12691/jfnr-11-4-3","url":null,"abstract":"","PeriodicalId":16096,"journal":{"name":"Journal of Food and Nutrition Research","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48137719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of n-Hexane Extract of Camellia Oleifera Fruit Hull on Inflammatory Responses in LPS-Induced RAW264.7 Cells","authors":"","doi":"10.12691/jfnr-11-4-4","DOIUrl":"https://doi.org/10.12691/jfnr-11-4-4","url":null,"abstract":"","PeriodicalId":16096,"journal":{"name":"Journal of Food and Nutrition Research","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44605028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evolution of Psychrotrophic Bacteria on Beef During Refrigeration","authors":"Benaissa Atika, Babelhadj Baaissa, Mimouni Yamina, Touhami Imene","doi":"10.12691/jfnr-11-4-2","DOIUrl":"https://doi.org/10.12691/jfnr-11-4-2","url":null,"abstract":"","PeriodicalId":16096,"journal":{"name":"Journal of Food and Nutrition Research","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45440374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are Nutrition Blogs a Trustworthy Source? Author Education, Evidence-Based Writing, and Types of Diets","authors":"Erfan Khazaee, Jeanne H. Freeland-Graves","doi":"10.12691/jfnr-11-4-1","DOIUrl":"https://doi.org/10.12691/jfnr-11-4-1","url":null,"abstract":"","PeriodicalId":16096,"journal":{"name":"Journal of Food and Nutrition Research","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44011372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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