首页 > 最新文献

Journal of forensic and legal medicine最新文献

英文 中文
Salivary biomarkers in forensic science: Bridging molecular biology and legal medicine 唾液生物标志物在法医学:连接分子生物学和法律医学
IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Pub Date : 2026-01-01 Epub Date: 2025-11-26 DOI: 10.1016/j.jflm.2025.103044
Arathi Padutholil Ajith Kumar , Premalatha Bidadi Rajashekaraiah , Sheethal Chandra Aralaguppe Chandraprakash , Parvathy Beena Chandran , Vaishaka Ashok Malali , Vidyadevi Chandavarkar
Saliva has emerged as a versatile and non-invasive biological specimen in forensic science. It is a rich source of genomic, transcriptomic, proteomic, metabolic, and microbiomic factors, offering significant potential in forensic investigations. This review explores the multi-dimensional aspects of salivary biomarkers in forensic science, integrating molecular biology with legal medicine.
It provides a comprehensive overview of the saliva composition, highlighting its biochemical constituents and the methodologies employed for its effective collection in forensic scenarios. From a molecular and analytical perspective, we delve into the diverse classes of salivary biomarkers, including genomic markers that enable individual and kinship profiling; transcriptomic and proteomic biomarkers that reveal gene expression and protein profiles that contribute in post-mortem interval estimation and physiological state evaluation; and metabolomic and microbiomic signatures which offer additional discriminatory power to infer health, lifestyle, and even geographic origins.
The forensic applications of these biomarkers and their growing acceptance in judicial proceedings, where the admissibility and evidential value of saliva-derived data are critically assessed, are discussed. Supported by relevant case studies, this review highlights the real-world utility and impact of salivary biomarkers in forensic practice. The challenges and limitations of saliva in forensics are addressed. Additionally, insights into future prospects, such as salivaomics, lab-on-a-chip platforms, and AI-driven data interpretation, are provided.
In conclusion, by mapping the intersection of molecular diagnostics and legal frameworks, this review underscores that saliva can be a revolutionary medium that advances the accuracy and accessibility of forensic identification by bridging its biological complexity with forensic applications.
唾液作为一种用途广泛、非侵入性的生物标本在法医学中已经出现。它是基因组、转录组、蛋白质组、代谢和微生物组因子的丰富来源,在法医调查中提供了巨大的潜力。本文将分子生物学与法医学相结合,从多方面探讨唾液生物标志物在法医学中的应用。它提供了唾液成分的全面概述,突出其生化成分和在法医场景中有效收集唾液的方法。从分子和分析的角度来看,我们深入研究了不同类别的唾液生物标志物,包括能够进行个体和亲属分析的基因组标记;转录组学和蛋白质组学生物标志物,揭示基因表达和蛋白质谱,有助于死后时间间隔估计和生理状态评估;代谢组学和微生物组学特征提供了额外的歧视性力量来推断健康,生活方式,甚至地理来源。讨论了这些生物标志物的法医应用及其在司法程序中的日益接受,其中唾液衍生数据的可采性和证据价值被严格评估。在相关案例研究的支持下,本综述强调了唾液生物标志物在法医实践中的现实效用和影响。解决了唾液在法医学中的挑战和局限性。此外,还提供了对未来前景的见解,如唾液组学、芯片实验室平台和人工智能驱动的数据解释。总之,通过绘制分子诊断和法律框架的交叉点,本综述强调了唾液可以成为一种革命性的媒介,通过将其生物学复杂性与法医应用联系起来,提高法医鉴定的准确性和可及性。
{"title":"Salivary biomarkers in forensic science: Bridging molecular biology and legal medicine","authors":"Arathi Padutholil Ajith Kumar ,&nbsp;Premalatha Bidadi Rajashekaraiah ,&nbsp;Sheethal Chandra Aralaguppe Chandraprakash ,&nbsp;Parvathy Beena Chandran ,&nbsp;Vaishaka Ashok Malali ,&nbsp;Vidyadevi Chandavarkar","doi":"10.1016/j.jflm.2025.103044","DOIUrl":"10.1016/j.jflm.2025.103044","url":null,"abstract":"<div><div>Saliva has emerged as a versatile and non-invasive biological specimen in forensic science. It is a rich source of genomic, transcriptomic, proteomic, metabolic, and microbiomic factors, offering significant potential in forensic investigations. This review explores the multi-dimensional aspects of salivary biomarkers in forensic science, integrating molecular biology with legal medicine.</div><div>It provides a comprehensive overview of the saliva composition, highlighting its biochemical constituents and the methodologies employed for its effective collection in forensic scenarios. From a molecular and analytical perspective, we delve into the diverse classes of salivary biomarkers, including genomic markers that enable individual and kinship profiling; transcriptomic and proteomic biomarkers that reveal gene expression and protein profiles that contribute in post-mortem interval estimation and physiological state evaluation; and metabolomic and microbiomic signatures which offer additional discriminatory power to infer health, lifestyle, and even geographic origins.</div><div>The forensic applications of these biomarkers and their growing acceptance in judicial proceedings, where the admissibility and evidential value of saliva-derived data are critically assessed, are discussed. Supported by relevant case studies, this review highlights the real-world utility and impact of salivary biomarkers in forensic practice. The challenges and limitations of saliva in forensics are addressed. Additionally, insights into future prospects, such as salivaomics, lab-on-a-chip platforms, and AI-driven data interpretation, are provided.</div><div>In conclusion, by mapping the intersection of molecular diagnostics and legal frameworks, this review underscores that saliva can be a revolutionary medium that advances the accuracy and accessibility of forensic identification by bridging its biological complexity with forensic applications.</div></div>","PeriodicalId":16098,"journal":{"name":"Journal of forensic and legal medicine","volume":"117 ","pages":"Article 103044"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145621560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age estimation based on Demirjian's method using third molars in individuals from Southeastern Brazil 基于Demirjian方法的年龄估计,使用来自巴西东南部个体的第三磨牙
IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Pub Date : 2026-01-01 Epub Date: 2025-11-24 DOI: 10.1016/j.jflm.2025.103045
Amanda Farias-Gomes , Maria Luíza dos Anjos Pontual , Thaísa Pinheiro Silva , Maria Fernanda Silva Andrade-Bortoletto , Matheus L. Oliveira , Francisco Haiter-Neto , Cleber Zanchettin , Deborah Queiroz Freitas
This study assessed the applicability of third molar mineralization stage for estimating chronological age in a Southeastern Brazilian population and tested a previously developed age estimation formula from a Northeastern Brazilian population. Digital panoramic radiographs of 1570 individuals aged 7–22 years were analyzed; 1260 radiographs were used to create the new formula, and 310 to test it. Two independent examiners classified the third molars on the radiographs according to Demirjian's developmental stages. Paired t-test compared chronological and estimated ages; Mann-Whitney test assessed sex differences in mineralization stages (α = 0.05). Multiple linear regression was used to develop a new age estimation formula. Chronological age was similar across all four third molars for different developmental stages, with no sex-related significant differences (p > 0.05). The initial appearance of third molar formation (stage A) and root apex closure (stage H) occurred at mean ages of 8.6 and 19.8 years, respectively. A strong correlation (R = 0.925) was found between chronological age and third molar mineralization stages. The previously developed formula significantly overestimated chronological age by approximately one year (p < 0.05). In contrast, the new formula achieved strong performance, explaining 85 % of the variance in the outcome (R2 = 0.85), with low prediction errors (MAE = 1.35; RMSE = 1.71), with no significant differences between estimated and chronological age for most age groups (p > 0.05). This study confirms the strong correlation between third molar mineralization stages and chronological age in a Southeastern Brazilian population. It also underscores the need for population-specific models, as the previously developed formula led to overestimation. The new formula provides a more accurate method for age estimation in this subpopulation, supporting its forensic and clinical applicability.
本研究评估了第三磨牙矿化阶段在巴西东南部人群中估计实足年龄的适用性,并测试了先前在巴西东北部人群中开发的年龄估计公式。分析了1570例7 ~ 22岁人群的数字全景x线照片;1260张x光片被用于创建新公式,310张用于测试。两名独立的检查人员根据Demirjian的发育阶段在x光片上对第三颗磨牙进行了分类。配对t检验比较了实际年龄和估计年龄;Mann-Whitney检验评价矿化阶段的性别差异(α = 0.05)。采用多元线性回归方法建立了新的年龄估计公式。所有四颗第三磨牙在不同发育阶段的实足年龄相似,没有性别相关的显著差异(p > 0.05)。第三磨牙形成(A期)和根尖闭合(H期)分别发生在平均8.6岁和19.8岁。年龄与第三磨牙矿化阶段有很强的相关性(R = 0.925)。先前开发的公式显著高估了实足年龄约1岁(p < 0.05)。相比之下,新公式取得了很好的效果,解释了85%的结果方差(R2 = 0.85),预测误差低(MAE = 1.35; RMSE = 1.71),大多数年龄组的估计年龄和实际年龄之间没有显著差异(p > 0.05)。这项研究证实了巴西东南部人群中第三磨牙矿化阶段与实足年龄之间的强烈相关性。它还强调需要针对特定人口的模型,因为以前开发的公式导致高估。新的公式提供了一个更准确的方法,年龄估计在这个亚群,支持其法医和临床适用性。
{"title":"Age estimation based on Demirjian's method using third molars in individuals from Southeastern Brazil","authors":"Amanda Farias-Gomes ,&nbsp;Maria Luíza dos Anjos Pontual ,&nbsp;Thaísa Pinheiro Silva ,&nbsp;Maria Fernanda Silva Andrade-Bortoletto ,&nbsp;Matheus L. Oliveira ,&nbsp;Francisco Haiter-Neto ,&nbsp;Cleber Zanchettin ,&nbsp;Deborah Queiroz Freitas","doi":"10.1016/j.jflm.2025.103045","DOIUrl":"10.1016/j.jflm.2025.103045","url":null,"abstract":"<div><div>This study assessed the applicability of third molar mineralization stage for estimating chronological age in a Southeastern Brazilian population and tested a previously developed age estimation formula from a Northeastern Brazilian population. Digital panoramic radiographs of 1570 individuals aged 7–22 years were analyzed; 1260 radiographs were used to create the new formula, and 310 to test it. Two independent examiners classified the third molars on the radiographs according to Demirjian's developmental stages. Paired <em>t</em>-test compared chronological and estimated ages; Mann-Whitney test assessed sex differences in mineralization stages (α = 0.05). Multiple linear regression was used to develop a new age estimation formula. Chronological age was similar across all four third molars for different developmental stages, with no sex-related significant differences (p &gt; 0.05). The initial appearance of third molar formation (stage A) and root apex closure (stage H) occurred at mean ages of 8.6 and 19.8 years, respectively. A strong correlation (R = 0.925) was found between chronological age and third molar mineralization stages. The previously developed formula significantly overestimated chronological age by approximately one year (p &lt; 0.05). In contrast, the new formula achieved strong performance, explaining 85 % of the variance in the outcome (R<sup>2</sup> = 0.85), with low prediction errors (MAE = 1.35; RMSE = 1.71), with no significant differences between estimated and chronological age for most age groups (p &gt; 0.05). This study confirms the strong correlation between third molar mineralization stages and chronological age in a Southeastern Brazilian population. It also underscores the need for population-specific models, as the previously developed formula led to overestimation. The new formula provides a more accurate method for age estimation in this subpopulation, supporting its forensic and clinical applicability.</div></div>","PeriodicalId":16098,"journal":{"name":"Journal of forensic and legal medicine","volume":"117 ","pages":"Article 103045"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145621538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective analysis of clinical toxicology results from 2017 to 2023: exploring the characteristics and prevalence trends of detected drugs and poisons 回顾性分析2017 - 2023年临床毒理学结果:探讨检出药物和毒物的特点及流行趋势
IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Pub Date : 2026-01-01 Epub Date: 2025-12-13 DOI: 10.1016/j.jflm.2025.103052
Yuxuan Fu , Sujing Zhang , Yibo Yan , Ping Xiang , Jian Li , Lei Xin , Hongxiao Deng , Hejian Wu , Xin Wang
To characterize temporal trends in toxic substance patterns involved in clinical toxicology cases in Shanghai, while considering regulatory changes, and to benchmark these findings against data from other regions. The clinical toxicology results reported by the Academy of Forensic Science (AFS) from January 2017 to December 2023 were collated, summarized, and retrospectively analyzed for the types and blood concentrations of different drugs and poisons. Overall, 4422 clinical toxicology cases were recorded, accounting for an average of approximately 630 cases per year, with 62 % presenting positive results. The positively detected substances were mainly clinical drugs and pesticides. The detected clinical drugs were predominantly sedative-hypnotics, antidepressants, and antipsychotics. Estazolam (n = 347), midazolam (n = 272), bromadiolone (n = 265), clonazepam (n = 228), and quetiapine (n = 199) were the top five most frequently detected substances in clinical toxicological cases. Other cases related to plant poisons, toxic heavy metals, and toxic alcohols were also recorded. The blood concentrations of the various drugs showed significant variability. This study highlights a concerning rise in psychoactive drug use, particularly sedative-hypnotics and antidepressants, reflecting a growing mental health burden in the population. This pattern is further supported by the frequent detection of blood drug concentrations exceeding therapeutic upper limits, indicating widespread non-therapeutic exposure. In response, psychotropic drug prescribing practices must be comprehensively strengthened through stricter regulations and the establishment of prescription surveillance to ensure rational and safe medication use. Additionally, a decline in certain toxicants, such as paraquat, suggests the effectiveness of policy interventions. The findings also emphasize the risks of polypharmacy and the need for enhanced poisoning prevention and emergency response systems.
在考虑监管变化的情况下,分析上海临床毒理学病例中涉及的有毒物质模式的时间趋势,并将这些发现与其他地区的数据进行比较。对法医学科学院(AFS) 2017年1月至2023年12月报告的临床毒理学结果进行整理、总结,并对不同药物和毒物的类型和血药浓度进行回顾性分析。总体而言,共记录了4422例临床毒理学病例,平均每年约630例,其中62%呈阳性结果。阳性物质主要为临床用药和农药。临床检出的药物以镇静催眠药、抗抑郁药和抗精神病药为主。艾司唑仑(347例)、咪达唑仑(272例)、溴代洛酮(265例)、氯硝西泮(228例)、喹硫平(199例)是临床毒理学病例中检出频率最高的5种物质。其他与植物中毒、有毒重金属和有毒酒精有关的案件也有记录。不同药物的血药浓度表现出显著的差异。这项研究强调了精神活性药物使用的增加,特别是镇静催眠药和抗抑郁药,反映了人口中日益增长的精神健康负担。血液中药物浓度超过治疗上限的频繁检测进一步支持了这种模式,表明广泛的非治疗性暴露。为此,必须通过更严格的法规和建立处方监督来全面加强精神药物的处方实践,以确保合理和安全用药。此外,某些有毒物质如百草枯的减少表明政策干预的有效性。研究结果还强调了多种用药的风险以及加强中毒预防和应急响应系统的必要性。
{"title":"Retrospective analysis of clinical toxicology results from 2017 to 2023: exploring the characteristics and prevalence trends of detected drugs and poisons","authors":"Yuxuan Fu ,&nbsp;Sujing Zhang ,&nbsp;Yibo Yan ,&nbsp;Ping Xiang ,&nbsp;Jian Li ,&nbsp;Lei Xin ,&nbsp;Hongxiao Deng ,&nbsp;Hejian Wu ,&nbsp;Xin Wang","doi":"10.1016/j.jflm.2025.103052","DOIUrl":"10.1016/j.jflm.2025.103052","url":null,"abstract":"<div><div>To characterize temporal trends in toxic substance patterns involved in clinical toxicology cases in Shanghai, while considering regulatory changes, and to benchmark these findings against data from other regions. The clinical toxicology results reported by the Academy of Forensic Science (AFS) from January 2017 to December 2023 were collated, summarized, and retrospectively analyzed for the types and blood concentrations of different drugs and poisons. Overall, 4422 clinical toxicology cases were recorded, accounting for an average of approximately 630 cases per year, with 62 % presenting positive results. The positively detected substances were mainly clinical drugs and pesticides. The detected clinical drugs were predominantly sedative-hypnotics, antidepressants, and antipsychotics. Estazolam (n = 347), midazolam (n = 272), bromadiolone (n = 265), clonazepam (n = 228), and quetiapine (n = 199) were the top five most frequently detected substances in clinical toxicological cases. Other cases related to plant poisons, toxic heavy metals, and toxic alcohols were also recorded. The blood concentrations of the various drugs showed significant variability. This study highlights a concerning rise in psychoactive drug use, particularly sedative-hypnotics and antidepressants, reflecting a growing mental health burden in the population. This pattern is further supported by the frequent detection of blood drug concentrations exceeding therapeutic upper limits, indicating widespread non-therapeutic exposure. In response, psychotropic drug prescribing practices must be comprehensively strengthened through stricter regulations and the establishment of prescription surveillance to ensure rational and safe medication use. Additionally, a decline in certain toxicants, such as paraquat, suggests the effectiveness of policy interventions. The findings also emphasize the risks of polypharmacy and the need for enhanced poisoning prevention and emergency response systems.</div></div>","PeriodicalId":16098,"journal":{"name":"Journal of forensic and legal medicine","volume":"117 ","pages":"Article 103052"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145786443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual violence and associated factors among female night students in Ethiopia: A systematic review and meta-analysis 埃塞俄比亚女夜校学生的性暴力及其相关因素:系统回顾和荟萃分析
IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Pub Date : 2026-01-01 Epub Date: 2025-12-18 DOI: 10.1016/j.jflm.2025.103053
Yeshiwas Ayale Ferede , Worku Chekol Tassew , Melese Legesse Mitku , Abiyie Demelash Gashe , Girum Meseret Ayenew , Adane Nigussie , Agerie Mengistie Zeleke

Background

Despite numerous efforts to prevent and control sexual violence in Ethiopia, the incidence continues to rise. It's crucial to have solid evidence to highlight the severity of the issue. Thus, this study aims to determine the overall prevalence of sexual violence and pinpoint the contributing factors among female night students in Ethiopia.

Method

A comprehensive and systematic literature search was conducted across various electronic databases, including PubMed, HINARI, Scopus, EMBASE, Web of Science, African Journal online (AJOL), and Google Scholar. The quality of the studies was evaluated using the Joanna Briggs Institute (JBI) critical appraisal checklist for analytical cross-sectional studies, consisting of nine criteria. The heterogeneity of the studies was assessed using the Cochrane Q and I2 test statistics. The pooled prevalence estimate of sexual violence among female night students was calculated using a random-effects model.

Result

Out of 6410 studies reviewed, six studies involving 2699 night students were deemed relevant. The pooled estimate of sexual violence among female night students in Ethiopia was found to be 43.58 % (95 % CI: 30.68, 56.48). Factors associated with sexual violence included rural residency (POR = 2.51; 95 % CI: 1.17, 5.41), alcohol use (AOR = 3.30; 95 % CI: 1.68, 6.48), having multiple sexual partners (POR = 2.78; 95 % CI: 1.97, 3.92), and a commute time to school exceeding 20 min (POR = 1.74; 95 % CI: 1.18, 2.58).

Conclusion

The research revealed that nearly half of female night students encountered sexual violence, with significant correlations identified between this violence and factors such as having multiple sexual partners, residing in rural areas during childhood, having a commute time to school of over 20 min, and having a history of alcohol use. To effectively address and prevent sexual violence, the Federal Ministry of Health (FMOH), policymakers, and stakeholders must prioritize these findings and take targeted actions.
尽管埃塞俄比亚为预防和控制性暴力做出了许多努力,但发生率仍在上升。有确凿的证据来强调问题的严重性是至关重要的。因此,本研究旨在确定埃塞俄比亚女夜校学生中性暴力的总体流行程度,并查明其影响因素。方法在PubMed、HINARI、Scopus、EMBASE、Web of Science、African Journal online (AJOL)和b谷歌Scholar等电子数据库中进行全面系统的文献检索。研究的质量使用乔安娜布里格斯研究所(JBI)对分析性横断面研究的关键评估清单进行评估,包括9个标准。采用Cochrane Q和I2检验统计量评估研究的异质性。利用随机效应模型计算了女夜校学生中性暴力的综合发生率。结果在6410项研究中,6项涉及2699名夜校学生的研究被认为是相关的。埃塞俄比亚女夜校学生的性暴力汇总估计为43.58% (95% CI: 30.68, 56.48)。与性暴力相关的因素包括农村居住(POR = 2.51; 95% CI: 1.17, 5.41)、饮酒(AOR = 3.30; 95% CI: 1.68, 6.48)、拥有多性伴侣(POR = 2.78; 95% CI: 1.97, 3.92)以及上学通勤时间超过20分钟(POR = 1.74; 95% CI: 1.18, 2.58)。研究表明,近一半的女夜校学生遭遇过性暴力,这种暴力与拥有多个性伴侣、童年时期居住在农村地区、上学通勤时间超过20分钟、有酗酒史等因素存在显著相关性。为了有效处理和预防性暴力,联邦卫生部、决策者和利益攸关方必须优先考虑这些调查结果,并采取有针对性的行动。
{"title":"Sexual violence and associated factors among female night students in Ethiopia: A systematic review and meta-analysis","authors":"Yeshiwas Ayale Ferede ,&nbsp;Worku Chekol Tassew ,&nbsp;Melese Legesse Mitku ,&nbsp;Abiyie Demelash Gashe ,&nbsp;Girum Meseret Ayenew ,&nbsp;Adane Nigussie ,&nbsp;Agerie Mengistie Zeleke","doi":"10.1016/j.jflm.2025.103053","DOIUrl":"10.1016/j.jflm.2025.103053","url":null,"abstract":"<div><h3>Background</h3><div>Despite numerous efforts to prevent and control sexual violence in Ethiopia, the incidence continues to rise. It's crucial to have solid evidence to highlight the severity of the issue. Thus, this study aims to determine the overall prevalence of sexual violence and pinpoint the contributing factors among female night students in Ethiopia.</div></div><div><h3>Method</h3><div>A comprehensive and systematic literature search was conducted across various electronic databases, including PubMed, HINARI, Scopus, EMBASE, Web of Science, African Journal online (AJOL), and Google Scholar. The quality of the studies was evaluated using the Joanna Briggs Institute (JBI) critical appraisal checklist for analytical cross-sectional studies, consisting of nine criteria. The heterogeneity of the studies was assessed using the Cochrane Q and I2 test statistics. The pooled prevalence estimate of sexual violence among female night students was calculated using a random-effects model.</div></div><div><h3>Result</h3><div>Out of 6410 studies reviewed, six studies involving 2699 night students were deemed relevant. The pooled estimate of sexual violence among female night students in Ethiopia was found to be 43.58 % (95 % CI: 30.68, 56.48). Factors associated with sexual violence included rural residency (POR = 2.51; 95 % CI: 1.17, 5.41), alcohol use (AOR = 3.30; 95 % CI: 1.68, 6.48), having multiple sexual partners (POR = 2.78; 95 % CI: 1.97, 3.92), and a commute time to school exceeding 20 min (POR = 1.74; 95 % CI: 1.18, 2.58).</div></div><div><h3>Conclusion</h3><div>The research revealed that nearly half of female night students encountered sexual violence, with significant correlations identified between this violence and factors such as having multiple sexual partners, residing in rural areas during childhood, having a commute time to school of over 20 min, and having a history of alcohol use. To effectively address and prevent sexual violence, the Federal Ministry of Health (FMOH), policymakers, and stakeholders must prioritize these findings and take targeted actions.</div></div>","PeriodicalId":16098,"journal":{"name":"Journal of forensic and legal medicine","volume":"117 ","pages":"Article 103053"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145786444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How people die inside: Fact patterns in civil litigation for in-custody deaths 人是如何在内部死亡的:羁押中死亡民事诉讼的事实模式。
IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Pub Date : 2026-01-01 Epub Date: 2025-12-05 DOI: 10.1016/j.jflm.2025.103048
Taleed El-Sabawi , Shelly Weizman , Regina LaBelle
Civil litigation provides a novel and underutilized source of information about deaths in U.S. jails, particularly when official data are incomplete. This study systematically analyzes verdicts, settlements and judgments to explore patterns in practices linked to preventable mortality in U.S jails.

Results

Content analysis of facts alleged in 90 cases filed between 2015 and 2020 revealed thematic patterns related to inadequate or delayed medical care. Alleged facts routinely included observable signs of serious medical need—such as incoherence, convulsions, or pleas for help—followed by failures to provide timely or medically appropriate care. In cases of suicide, allegations commonly describe known mental health conditions, discontinued medication, and lapses in monitoring or suicide prevention protocols. Despite repeated warnings—by the individuals themselves, fellow incarcerated persons, or family members—jail staff frequently failed to act. A small subset of cases resulted in judgments for the defense, often where some care was provided or protocols were followed, even if outcomes were still fatal.

Conclusion

These findings suggest that in cases resulting in reported settlements, verdicts or judgments in-custody deaths in the U.S. could be prevented through improved intake screening, timely medical monitoring, care coordination, and adherence to established protocols. Litigation records offer important insight into how systemic failures contribute to jail mortality, with implications for policy, public health, and correctional practice.
民事诉讼提供了一种新的、未得到充分利用的关于美国监狱死亡的信息来源,特别是在官方数据不完整的情况下。本研究系统地分析了判决、和解和判决,以探索与美国监狱中可预防的死亡率相关的实践模式。结果:对2015年至2020年间提交的90起案件所指控事实的内容分析揭示了与医疗服务不足或延误相关的主题模式。所谓的事实通常包括可观察到的严重医疗需求的迹象——如语无伦次、抽搐或求助——随后未能提供及时或适当的医疗护理。在自杀案件中,指控通常描述已知的精神健康状况、停止用药以及监测或预防自杀协议的失误。尽管囚犯本人、狱友或家属一再警告,但监狱工作人员经常不采取行动。一小部分案件的结果是被告胜诉,通常是在提供了一些护理或遵循了协议的情况下,即使结果仍然是致命的。结论:这些发现表明,在报告的和解、判决或判决的案件中,美国可以通过改进摄入筛查、及时的医疗监测、护理协调和遵守既定协议来预防在押人员死亡。诉讼记录提供了重要的见解,了解系统故障如何导致监狱死亡率,并对政策、公共卫生和惩教实践产生影响。
{"title":"How people die inside: Fact patterns in civil litigation for in-custody deaths","authors":"Taleed El-Sabawi ,&nbsp;Shelly Weizman ,&nbsp;Regina LaBelle","doi":"10.1016/j.jflm.2025.103048","DOIUrl":"10.1016/j.jflm.2025.103048","url":null,"abstract":"<div><div>Civil litigation provides a novel and underutilized source of information about deaths in U.S. jails, particularly when official data are incomplete. This study systematically analyzes verdicts, settlements and judgments to explore patterns in practices linked to preventable mortality in U.S jails.</div></div><div><h3>Results</h3><div>Content analysis of facts alleged in 90 cases filed between 2015 and 2020 revealed thematic patterns related to inadequate or delayed medical care. Alleged facts routinely included observable signs of serious medical need—such as incoherence, convulsions, or pleas for help—followed by failures to provide timely or medically appropriate care. In cases of suicide, allegations commonly describe known mental health conditions, discontinued medication, and lapses in monitoring or suicide prevention protocols. Despite repeated warnings—by the individuals themselves, fellow incarcerated persons, or family members—jail staff frequently failed to act. A small subset of cases resulted in judgments for the defense, often where some care was provided or protocols were followed, even if outcomes were still fatal.</div></div><div><h3>Conclusion</h3><div>These findings suggest that in cases resulting in reported settlements, verdicts or judgments in-custody deaths in the U.S. could be prevented through improved intake screening, timely medical monitoring, care coordination, and adherence to established protocols. Litigation records offer important insight into how systemic failures contribute to jail mortality, with implications for policy, public health, and correctional practice.</div></div>","PeriodicalId":16098,"journal":{"name":"Journal of forensic and legal medicine","volume":"117 ","pages":"Article 103048"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145717081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of psychoactive substances and attention-related impairments on driving performance: Sex differences and road crash involvement 精神活性物质和注意力相关障碍对驾驶表现的影响:性别差异和道路交通事故参与。
IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Pub Date : 2026-01-01 Epub Date: 2025-12-12 DOI: 10.1016/j.jflm.2025.103050
Claudio Terranova , Clara Cestonaro , Stefano Palumbi , Laura Marino , Alessandro Gentili , Francesco Pozzebon , Rocco Miazzi , Anna Aprile

Introduction

Crashes are a global public health concern, with psychoactive substance use and attention impairments potentially increasing risk and affecting male and female drivers differently. This study aims to identify factors related to psychoactive substance use and attention impairments that predict road crash involvement by sex, offering insights for targeted prevention effort.

Methods

This observational study examined individuals assessed for driving license reissuance after driving under the influence of alcohol and/or drugs. Data collected included personal and sociodemographic details, results from a Continuous performance test (CPT-3) (a neuropsychological test assessing inattentiveness, impulsivity, sustained attention, and vigilance), and toxicological analyses of biological samples. Statistical analyses (chi-square, logistic regression, and ROC curve) aimed at identifing sex-specific predictors of road crash involvement.

Results

The study included 169 participants (82.8 % males, 17.2 % females). Initial univariate analyses indicated sex differences that were not confirmed after Bonferroni correction for multiple comparisons. Logistic regression found blood alcohol concentration predictive of crashes in males (p = 0.005, OR = 2.52), while inattentiveness was a major factor for females (p = 0.045, OR = 12.0). In the combined model, sex itself was not an independent predictor after adjusting for these factors. The model showed moderate accuracy for males (ROC-AUC = 0.695) and higher accuracy for females (ROC-AUC = 0.816), suggesting that inattentiveness may play a particularly important role in predicting crashes in the female subgroup.

Conclusions

Inattentiveness and alcohol use emerged as key predictors of crash involvement, with inattentiveness showing particular relevance in the female subgroup. Prevention should focus on modifiable risk factors rather than sex. The model's higher accuracy in females suggests attentional measures may help identify at-risk drivers, though the small female sample limits generalizability.
导言:车祸是一个全球性的公共卫生问题,精神活性物质的使用和注意力障碍可能增加风险,对男性和女性司机的影响不同。本研究旨在确定与精神活性物质使用和注意力障碍相关的因素,这些因素可以预测性别道路交通事故的发生,为有针对性的预防工作提供见解。方法:本观察性研究调查了在酒精和/或药物影响下驾驶后被评估补发驾照的个体。收集的数据包括个人和社会人口学细节,持续表现测试(CPT-3)(一种评估注意力不集中、冲动、持续注意力和警惕性的神经心理学测试)的结果,以及生物样本的毒理学分析。统计分析(卡方、逻辑回归和ROC曲线)旨在确定道路交通事故涉及的性别特异性预测因子。结果:研究纳入169名参与者(男性82.8%,女性17.2%)。最初的单变量分析表明,在Bonferroni校正多重比较后,性别差异未得到证实。Logistic回归发现血液酒精浓度可预测男性的撞车(p = 0.005, OR = 2.52),而注意力不集中是女性的主要因素(p = 0.045, OR = 12.0)。在综合模型中,在调整了这些因素后,性别本身并不是一个独立的预测因子。该模型显示,男性的准确度中等(ROC-AUC = 0.695),女性的准确度较高(ROC-AUC = 0.816),这表明注意力不集中可能在预测女性亚组的撞车事故中起着特别重要的作用。结论:注意力不集中和饮酒是导致车祸的关键因素,其中注意力不集中在女性亚组中表现出特别的相关性。预防应侧重于可改变的危险因素,而不是性别。该模型在女性中的较高准确性表明,注意力测量可能有助于识别有风险的驱动因素,尽管女性样本较少限制了普遍性。
{"title":"Impact of psychoactive substances and attention-related impairments on driving performance: Sex differences and road crash involvement","authors":"Claudio Terranova ,&nbsp;Clara Cestonaro ,&nbsp;Stefano Palumbi ,&nbsp;Laura Marino ,&nbsp;Alessandro Gentili ,&nbsp;Francesco Pozzebon ,&nbsp;Rocco Miazzi ,&nbsp;Anna Aprile","doi":"10.1016/j.jflm.2025.103050","DOIUrl":"10.1016/j.jflm.2025.103050","url":null,"abstract":"<div><h3>Introduction</h3><div>Crashes are a global public health concern, with psychoactive substance use and attention impairments potentially increasing risk and affecting male and female drivers differently. This study aims to identify factors related to psychoactive substance use and attention impairments that predict road crash involvement by sex, offering insights for targeted prevention effort.</div></div><div><h3>Methods</h3><div>This observational study examined individuals assessed for driving license reissuance after driving under the influence of alcohol and/or drugs. Data collected included personal and sociodemographic details, results from a Continuous performance test (CPT-3) (a neuropsychological test assessing inattentiveness, impulsivity, sustained attention, and vigilance), and toxicological analyses of biological samples. Statistical analyses (chi-square, logistic regression, and ROC curve) aimed at identifing sex-specific predictors of road crash involvement.</div></div><div><h3>Results</h3><div>The study included 169 participants (82.8 % males, 17.2 % females). Initial univariate analyses indicated sex differences that were not confirmed after Bonferroni correction for multiple comparisons. Logistic regression found blood alcohol concentration predictive of crashes in males (p = 0.005, OR = 2.52), while inattentiveness was a major factor for females (p = 0.045, OR = 12.0). In the combined model, sex itself was not an independent predictor after adjusting for these factors. The model showed moderate accuracy for males (ROC-AUC = 0.695) and higher accuracy for females (ROC-AUC = 0.816), suggesting that inattentiveness may play a particularly important role in predicting crashes in the female subgroup.</div></div><div><h3>Conclusions</h3><div>Inattentiveness and alcohol use emerged as key predictors of crash involvement, with inattentiveness showing particular relevance in the female subgroup. Prevention should focus on modifiable risk factors rather than sex. The model's higher accuracy in females suggests attentional measures may help identify at-risk drivers, though the small female sample limits generalizability.</div></div>","PeriodicalId":16098,"journal":{"name":"Journal of forensic and legal medicine","volume":"117 ","pages":"Article 103050"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145776918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intrinsic factors influencing the post-mortem mechanical excitability of human skeletal muscle 影响人体骨骼肌死后机械兴奋性的内在因素。
IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Pub Date : 2026-01-01 Epub Date: 2025-12-22 DOI: 10.1016/j.jflm.2025.103055
H. Stigter, J. Kloosterman, T. Krap, W.L.J.M. Duijst
<div><h3>Background</h3><div>Post-mortem, supravital muscle reaction (SMR) of human skeletal muscle is dependent on energy supply. Intrinsic variables, like peri-mortem body temperature and underlying diseases, influence the rate of cell metabolism in skeletal muscle cells post-mortem, and thus the available energy for SMR.</div></div><div><h3>Objectives</h3><div>A field study was conducted, comprising deceased found under differing conditions. We investigated the influence of the body temperature of the deceased on the outcome of post-mortem mechanical stimulation of skeletal muscle in the first hours post-mortem. In addition, we investigated the influence of sex, age, state of rigor mortis and the length of the dying process on SMR. Furthermore, we hypothesized that the outcome of post-mortem muscle stimulation could differ between musculus biceps brachii (MBB) and the musculus brachioradialis (MBR) on the same body examined at the same time, due to a higher cooling velocity of more peripheral located skeletal muscles (MBR).</div></div><div><h3>Methods</h3><div>In the period of January 2017 to August 2023 four forensic physicians from two different regions in the Netherlands performed mechanical stimulation of both upper and forearms of deceased with a known or an estimated PMI of <14 h, by using a reflex hammer. The research population concerned in-hospital-deaths, out-of-hospital deaths that were transferred to the morgue of a hospital, and out-of-hospital deaths that were examined at the place where the body was found. The sex and age of the deceased, body temperature, and state of rigor mortis were registered in the Dutch national register of forensic medicine, which was used as a data resource. The length of the dying process was registered separately using SPSS 27.0 which also served as a data resource. The Welch Two Sample <em>t</em>-test, chi-squared test, logistic regression and multiple logistic regression were performed to investigate the influence of the PMI, body temperature, sex, age, state of rigor mortis and the length of the dying process on the outcome of SMR. Statistical analyses were performed by using R 4.4.1. Significance was accepted at P < 0.05.</div></div><div><h3>Results</h3><div>In total, 142 cases were included, in which musculus biceps brachii (MBB) and the musculus brachioradialis (MBR) on both arms were mechanically stimulated with a reflex hammer. The population consisted out of 65 males (mean age: 73.4 ± 16.8 years) and 77 females (mean age: 82.1 ± 13.0 years). SMR was present in 74 out of 142 cases (52.1 %). The mean PMI did not differ significantly between cases with a positive SMR (157.3 min) and cases showing no SMR (168.4 min). The number of male cases that showed SMR (63.1 %) was significantly higher than the number of female cases (42.9 %) that showed SMR. No relationship was detected between age, body temperature, rigor mortis and the length of the dying process, and the outcome of post-mortem musc
背景:人死后,骨骼肌的上肌反应(SMR)依赖于能量供应。内在变量,如死前体温和潜在疾病,会影响死后骨骼肌细胞的细胞代谢率,从而影响SMR的可用能量。目的:进行实地研究,包括在不同条件下发现的死者。我们研究了死者体温对死后几个小时内骨骼肌机械刺激结果的影响。此外,我们还调查了性别、年龄、尸僵状态和死亡过程长度对SMR的影响。此外,我们假设死后肌肉刺激的结果可能会在同一身体上的肱二头肌(MBB)和肱桡肌(MBR)之间有所不同,因为更多的外围骨骼肌(MBR)的冷却速度更高。方法:在2017年1月至2023年8月期间,来自荷兰两个不同地区的四名法医对已知或估计PMI的死者的上臂和前臂进行机械刺激。结果:共纳入142例,其中用反射锤机械刺激双臂肱二头肌(MBB)和肱桡肌(MBR)。男性65例,平均年龄73.4±16.8岁;女性77例,平均年龄82.1±13.0岁。142例中有74例(52.1%)出现SMR。SMR阳性病例(157.3 min)和无SMR病例(168.4 min)的平均PMI无显著差异。男性出现SMR的病例数(63.1%)明显高于女性(42.9%)。年龄、体温、尸僵程度、死亡过程长度与死后早期肌肉刺激的结果没有关系。在142例病例中,有28例(19.7%)在同一身体上观察到MBB和MBR在死后肌肉刺激结果上的差异。在尸僵的连续阶段,SMR的百分比下降。在尸体完全僵直的情况下,没有观察到SMR。结论:目前的研究表明,男性和女性死者死后早期的死后肌肉刺激结果有显著差异。未发现体温、年龄、尸僵程度和死亡过程长度对死后早期肌肉刺激的结果有影响,但由于研究的局限性,必须谨慎对待这一结果。在19.7%的病例中,在同一身体上MBB和MBR之间观察到死后肌肉刺激结果的差异。
{"title":"Intrinsic factors influencing the post-mortem mechanical excitability of human skeletal muscle","authors":"H. Stigter,&nbsp;J. Kloosterman,&nbsp;T. Krap,&nbsp;W.L.J.M. Duijst","doi":"10.1016/j.jflm.2025.103055","DOIUrl":"10.1016/j.jflm.2025.103055","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Post-mortem, supravital muscle reaction (SMR) of human skeletal muscle is dependent on energy supply. Intrinsic variables, like peri-mortem body temperature and underlying diseases, influence the rate of cell metabolism in skeletal muscle cells post-mortem, and thus the available energy for SMR.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objectives&lt;/h3&gt;&lt;div&gt;A field study was conducted, comprising deceased found under differing conditions. We investigated the influence of the body temperature of the deceased on the outcome of post-mortem mechanical stimulation of skeletal muscle in the first hours post-mortem. In addition, we investigated the influence of sex, age, state of rigor mortis and the length of the dying process on SMR. Furthermore, we hypothesized that the outcome of post-mortem muscle stimulation could differ between musculus biceps brachii (MBB) and the musculus brachioradialis (MBR) on the same body examined at the same time, due to a higher cooling velocity of more peripheral located skeletal muscles (MBR).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;In the period of January 2017 to August 2023 four forensic physicians from two different regions in the Netherlands performed mechanical stimulation of both upper and forearms of deceased with a known or an estimated PMI of &lt;14 h, by using a reflex hammer. The research population concerned in-hospital-deaths, out-of-hospital deaths that were transferred to the morgue of a hospital, and out-of-hospital deaths that were examined at the place where the body was found. The sex and age of the deceased, body temperature, and state of rigor mortis were registered in the Dutch national register of forensic medicine, which was used as a data resource. The length of the dying process was registered separately using SPSS 27.0 which also served as a data resource. The Welch Two Sample &lt;em&gt;t&lt;/em&gt;-test, chi-squared test, logistic regression and multiple logistic regression were performed to investigate the influence of the PMI, body temperature, sex, age, state of rigor mortis and the length of the dying process on the outcome of SMR. Statistical analyses were performed by using R 4.4.1. Significance was accepted at P &lt; 0.05.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;In total, 142 cases were included, in which musculus biceps brachii (MBB) and the musculus brachioradialis (MBR) on both arms were mechanically stimulated with a reflex hammer. The population consisted out of 65 males (mean age: 73.4 ± 16.8 years) and 77 females (mean age: 82.1 ± 13.0 years). SMR was present in 74 out of 142 cases (52.1 %). The mean PMI did not differ significantly between cases with a positive SMR (157.3 min) and cases showing no SMR (168.4 min). The number of male cases that showed SMR (63.1 %) was significantly higher than the number of female cases (42.9 %) that showed SMR. No relationship was detected between age, body temperature, rigor mortis and the length of the dying process, and the outcome of post-mortem musc","PeriodicalId":16098,"journal":{"name":"Journal of forensic and legal medicine","volume":"117 ","pages":"Article 103055"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Crossing Borders: A look at migrant deaths in the Caribbean 跨越边界:加勒比地区移民死亡情况调查。
IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Pub Date : 2026-01-01 Epub Date: 2025-11-24 DOI: 10.1016/j.jflm.2025.103042
Ken Obenson
{"title":"Crossing Borders: A look at migrant deaths in the Caribbean","authors":"Ken Obenson","doi":"10.1016/j.jflm.2025.103042","DOIUrl":"10.1016/j.jflm.2025.103042","url":null,"abstract":"","PeriodicalId":16098,"journal":{"name":"Journal of forensic and legal medicine","volume":"117 ","pages":"Article 103042"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145851757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical liability related legislation and insurance policies around the world: A narrative literature review 世界各国医疗责任相关立法与保险政策:叙述性文献回顾
IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Pub Date : 2026-01-01 Epub Date: 2025-11-19 DOI: 10.1016/j.jflm.2025.103040
Ioannis Ketsekioulafis , Konstantinos Katsos , Dimitrios Kouzos , Chara Spiliopoulou , Theodoros Lytras , Emmanouil I. Sakelliadis
<div><h3>Introduction</h3><div>Medical law defines the rules of healthcare by specifying the rights of healthcare consumers while at the same time defining the obligations of healthcare providers. When clinicians fail to provide the standard of care, medical malpractice claims arise, leading to medical liability. While many malpractice claims allege deviation from the <em>lex artis</em>, a substantial proportion do not ultimately establish negligence and are dismissed or settled without a finding of fault. Due to the significant impact of medical negligence on the quality of medical care, as well as on the domestic and global economy, different countries adopt different systems for managing these disputes. Finally, the mandatory or non-mandatory medical malpractice insurance makes doctors carry out their medical work without the fear of medical liability. In fact, in most countries today, doctors are given the opportunity to choose between claims-made and occurrence-based policies of medical malpractice insurance.</div></div><div><h3>Materials and methods</h3><div>The study is a narrative review of scientific and legal works from different countries. For the comparison of medical liability systems and insurance policies a comprehensive review of databases and legal texts was conducted.</div></div><div><h3>Results</h3><div>This study compares medical liability and malpractice insurance systems across countries, examining variations in the handling of malpractice claims and their implications. The system is adversarial in many countries, especially in the United States, to allow for a substantial compensation, while other countries, such as the United Kingdom and Germany, focus on mediation and structured compensation processes. Notably, France, Japan and other countries follow a no-fault system, of reasoning that the system is more efficient in the sense that it reduces the patient's burden of proving negligence and thus expedites the compensation. These findings reveal how each country negotiates the balance between patient rights and healthcare provider protections, and, in turn, how these negotiations affect malpractice insurance costs and legal reforms.</div></div><div><h3>Discussion</h3><div>The analysis contrasts fault-based systems which offer large compensation awards with no-fault systems which focus on quick compensation but may lack accountability. Countries with high litigation rates like the US and Brazil have higher insurance costs, while countries like Canada and Australia have stabilized their systems through reforms. Medical liability insurance options, claims-made versus occurrence-based, raise different economic and legal concerns. Occurrence-based policies are more expensive for younger professionals, but they provide longer-term coverage than claims-made policies.</div></div><div><h3>Conclusion</h3><div>Global medical liability frameworks vary considerably, reflecting cultural, economic and legal contexts. However, the compari
医疗法律规定了医疗保健规则,具体规定了医疗保健消费者的权利,同时规定了医疗保健提供者的义务。当临床医生不能提供标准的护理,医疗事故索赔出现,导致医疗责任。虽然许多医疗事故索赔声称违反了《劳动法》,但相当大比例的索赔最终没有确立过失,在没有发现过失的情况下被驳回或解决。由于医疗过失对医疗质量以及对国内和全球经济的重大影响,不同的国家采用不同的制度来管理这些纠纷。最后,强制性或非强制性医疗事故保险使医生在进行医疗工作时不必担心医疗责任。事实上,今天在大多数国家,医生都有机会在医疗事故保险的索赔政策和基于事故发生的政策之间作出选择。材料与方法本研究是对各国科学和法律著作的叙述性回顾。为了比较医疗责任制度和保险政策,对数据库和法律文本进行了全面审查。结果本研究比较了各国的医疗责任和医疗事故保险制度,检查了处理医疗事故索赔的差异及其影响。在许多国家,特别是在美国,该制度是对抗性的,以允许大量赔偿,而其他国家,如英国和德国,则侧重于调解和有组织的赔偿程序。值得注意的是,法国、日本和其他国家采用无过错制度,理由是该制度更有效,因为它减少了患者证明过失的负担,从而加快了赔偿。这些发现揭示了每个国家如何在患者权利和医疗保健提供者保护之间进行谈判,以及这些谈判如何影响医疗事故保险成本和法律改革。该分析对比了基于故障的系统(提供大量补偿)和无故障系统(侧重于快速补偿,但可能缺乏问责制)。美国和巴西等诉讼率较高的国家的保险成本较高,而加拿大和澳大利亚等国则通过改革稳定了其制度。医疗责任保险的选择,无论是索赔还是事故发生,引起了不同的经济和法律问题。对于较年轻的专业人员来说,以事件发生为基础的保单较为昂贵,但它们比索赔保单提供更长期的保险。全球医疗责任框架差异很大,反映了文化、经济和法律背景。然而,比较表明,没有一个系统是完美的,每个系统都有值得学习的地方。
{"title":"Medical liability related legislation and insurance policies around the world: A narrative literature review","authors":"Ioannis Ketsekioulafis ,&nbsp;Konstantinos Katsos ,&nbsp;Dimitrios Kouzos ,&nbsp;Chara Spiliopoulou ,&nbsp;Theodoros Lytras ,&nbsp;Emmanouil I. Sakelliadis","doi":"10.1016/j.jflm.2025.103040","DOIUrl":"10.1016/j.jflm.2025.103040","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Introduction&lt;/h3&gt;&lt;div&gt;Medical law defines the rules of healthcare by specifying the rights of healthcare consumers while at the same time defining the obligations of healthcare providers. When clinicians fail to provide the standard of care, medical malpractice claims arise, leading to medical liability. While many malpractice claims allege deviation from the &lt;em&gt;lex artis&lt;/em&gt;, a substantial proportion do not ultimately establish negligence and are dismissed or settled without a finding of fault. Due to the significant impact of medical negligence on the quality of medical care, as well as on the domestic and global economy, different countries adopt different systems for managing these disputes. Finally, the mandatory or non-mandatory medical malpractice insurance makes doctors carry out their medical work without the fear of medical liability. In fact, in most countries today, doctors are given the opportunity to choose between claims-made and occurrence-based policies of medical malpractice insurance.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Materials and methods&lt;/h3&gt;&lt;div&gt;The study is a narrative review of scientific and legal works from different countries. For the comparison of medical liability systems and insurance policies a comprehensive review of databases and legal texts was conducted.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;This study compares medical liability and malpractice insurance systems across countries, examining variations in the handling of malpractice claims and their implications. The system is adversarial in many countries, especially in the United States, to allow for a substantial compensation, while other countries, such as the United Kingdom and Germany, focus on mediation and structured compensation processes. Notably, France, Japan and other countries follow a no-fault system, of reasoning that the system is more efficient in the sense that it reduces the patient's burden of proving negligence and thus expedites the compensation. These findings reveal how each country negotiates the balance between patient rights and healthcare provider protections, and, in turn, how these negotiations affect malpractice insurance costs and legal reforms.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Discussion&lt;/h3&gt;&lt;div&gt;The analysis contrasts fault-based systems which offer large compensation awards with no-fault systems which focus on quick compensation but may lack accountability. Countries with high litigation rates like the US and Brazil have higher insurance costs, while countries like Canada and Australia have stabilized their systems through reforms. Medical liability insurance options, claims-made versus occurrence-based, raise different economic and legal concerns. Occurrence-based policies are more expensive for younger professionals, but they provide longer-term coverage than claims-made policies.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;Global medical liability frameworks vary considerably, reflecting cultural, economic and legal contexts. However, the compari","PeriodicalId":16098,"journal":{"name":"Journal of forensic and legal medicine","volume":"117 ","pages":"Article 103040"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145577826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An investigation of shored gunshot exit wound morphologies using a range of forensically relevant surfaces 使用一系列法医相关表面对射击出口伤口形态进行调查
IF 1.2 4区 医学 Q3 MEDICINE, LEGAL Pub Date : 2026-01-01 Epub Date: 2025-11-21 DOI: 10.1016/j.jflm.2025.103035
Bandula Nishshanka , Chris Shepherd , Randika Ariyarathna , Paranitharan Paranirubasingam , Amila Rathnayaka
Shored exit wounds are produced when the skin at the point of the bullet exit is supported or buttressed by some object or surface, causing an abraded ring around the shored exit wound. This work looks to add critical understanding of shored wound processes on a range of surface types, expanding on the currently limited literature that focuses only on soft shoring materials. This large empirical study was conducted to develop a deeper understanding of shored exit wounds for a range of common surface types available in contemporary urban environments. To facilitate this, two ammunition types (5.56 mm and 7.62 mm) were fired into a porcine model designed to simulate the downward force of a human body pressing into various modern building materials. The exit wounds produced by shoring the porcine model on wall tiles, concrete, and two engineered wood types (MDF and Melamine) significantly contrast with the existing, more generalised explanation of shored exit wounds. This highlights the necessity for a more valid, target-type-specific approach to interpreting shored exit wound characteristics. The study highlights that hard-shoring surfaces produce comparatively larger exit wounds, while irregular surfaces give rise to increased shoring and soft surfaces under pressure, produce less shoring. It also reports novel shored exit wound features and wounding mechanisms not documented previously that have potential forensic investigative value in helping determine if a gunshot wound has resulted from a shored scenario or not. While significantly adding to the understanding of shored exit wounds for forensic pathology practice, the study's findings suggest that the shored exit wound characteristics can be interpreted according to different target types, such as yielding and non-yielding surfaces.
当子弹出口处的皮肤受到某种物体或表面的支撑或支撑时,就会产生一种擦伤性伤口。这项工作旨在增加对一系列表面类型的支撑伤口过程的批判性理解,扩展目前有限的文献,仅关注软支撑材料。这项大型实证研究旨在对当代城市环境中一系列常见表面类型的岸边出口伤口进行更深入的了解。为了方便起见,两种弹药(5.56毫米和7.62毫米)被发射到猪模型中,以模拟人体压入各种现代建筑材料的向下力。将猪模型支撑在墙砖、混凝土和两种工程木材(中密度纤维板和三聚氰胺)上产生的出口伤口与现有的、更普遍的关于支撑出口伤口的解释明显相反。这凸显了需要一种更有效的、针对目标类型的方法来解释岸边出口伤的特征。该研究强调,硬支撑表面会产生相对较大的出口伤口,而不规则表面会增加支撑,而软表面在压力下会减少支撑。报告还报告了以前没有记录的新的受冲击出口伤口特征和伤害机制,这些特征和机制在帮助确定枪伤是否由受冲击情景引起方面具有潜在的法医调查价值。虽然在法医病理学实践中显著增加了对岸边出口伤的理解,但研究结果表明,岸边出口伤的特征可以根据不同的目标类型(如屈服面和非屈服面)来解释。
{"title":"An investigation of shored gunshot exit wound morphologies using a range of forensically relevant surfaces","authors":"Bandula Nishshanka ,&nbsp;Chris Shepherd ,&nbsp;Randika Ariyarathna ,&nbsp;Paranitharan Paranirubasingam ,&nbsp;Amila Rathnayaka","doi":"10.1016/j.jflm.2025.103035","DOIUrl":"10.1016/j.jflm.2025.103035","url":null,"abstract":"<div><div>Shored exit wounds are produced when the skin at the point of the bullet exit is supported or buttressed by some object or surface, causing an abraded ring around the shored exit wound. This work looks to add critical understanding of shored wound processes on a range of surface types, expanding on the currently limited literature that focuses only on soft shoring materials. This large empirical study was conducted to develop a deeper understanding of shored exit wounds for a range of common surface types available in contemporary urban environments. To facilitate this, two ammunition types (5.56 mm and 7.62 mm) were fired into a porcine model designed to simulate the downward force of a human body pressing into various modern building materials. The exit wounds produced by shoring the porcine model on wall tiles, concrete, and two engineered wood types (MDF and Melamine) significantly contrast with the existing, more generalised explanation of shored exit wounds. This highlights the necessity for a more valid, target-type-specific approach to interpreting shored exit wound characteristics. The study highlights that hard-shoring surfaces produce comparatively larger exit wounds, while irregular surfaces give rise to increased shoring and soft surfaces under pressure, produce less shoring. It also reports novel shored exit wound features and wounding mechanisms not documented previously that have potential forensic investigative value in helping determine if a gunshot wound has resulted from a shored scenario or not. While significantly adding to the understanding of shored exit wounds for forensic pathology practice, the study's findings suggest that the shored exit wound characteristics can be interpreted according to different target types, such as yielding and non-yielding surfaces.</div></div>","PeriodicalId":16098,"journal":{"name":"Journal of forensic and legal medicine","volume":"117 ","pages":"Article 103035"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145621561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of forensic and legal medicine
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1