Ngwatshipane M. Mashabela, Tshepiso P. Ndhlovu, Wilfred Otang-Mbeng
{"title":"Metabolomic and chemometric profiles of Tribulus terrestris L. from three different locations in Mpumalanga province, South Africa","authors":"Ngwatshipane M. Mashabela, Tshepiso P. Ndhlovu, Wilfred Otang-Mbeng","doi":"10.4102/jomped.v7i1.184","DOIUrl":"https://doi.org/10.4102/jomped.v7i1.184","url":null,"abstract":"","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":"223 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135109352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Coopoosamy, Karishma Singh, K. Naidoo, D. S. Nadasan
{"title":"The role of phytomedicine: Bridging the gap between the past, present, and future","authors":"R. Coopoosamy, Karishma Singh, K. Naidoo, D. S. Nadasan","doi":"10.4102/jomped.v7i1.197","DOIUrl":"https://doi.org/10.4102/jomped.v7i1.197","url":null,"abstract":"","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41475446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Marunych, D. L. Kolesnik, O. Pyaskovskaya, G. Solyanik, A. V. Rebriev, T. Chernyshenko, N. Lugovska, T. Kozytska, Andriy V. Gudzenko
{"title":"The impact of extract of mistletoe on tumour cells and hemostasis of human plasma","authors":"R. Marunych, D. L. Kolesnik, O. Pyaskovskaya, G. Solyanik, A. V. Rebriev, T. Chernyshenko, N. Lugovska, T. Kozytska, Andriy V. Gudzenko","doi":"10.4102/jomped.v7i1.186","DOIUrl":"https://doi.org/10.4102/jomped.v7i1.186","url":null,"abstract":"","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49031016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pleurostylia capensis Turcz (Loes): A review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses","authors":"Nokukhanya Thembane","doi":"10.4102/jomped.v7i1.187","DOIUrl":"https://doi.org/10.4102/jomped.v7i1.187","url":null,"abstract":"","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41449643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hadiza Bello, Umar A. Katsayal, Aminu A. Ambi, Yusuf B. Abubakar
Background: Isoberlinia (Craib and Stapf) is a genus with high economic and pharmacological values.Aim: This study aimed at establishing the morphological, anatomical and molecular characterisation of the leaves of I. doka and I. tomentosa, which were conducted for proper authentication.Setting: The leaves of I. doka and I. tomentosa were obtained from Shika, kaduna State, Nigeria.Method: Morphological and anatomical characters were determined according to standard procedures, while molecular identifications were performed using ribulose-1,5-bisphosphate carboxylase (rbcl) gene and internal transcribed spacer (ITS) DNA barcode’s region.Result: Morphological studies revealed similar features for both species except for the shiny leaves of I. doka and rough abaxial surfaces of I. tomentosa because of the presence of trichomes. Variations were observed in their epidermal features, stomatal index, stomata frequency, presence or absence of trichomes, trichomes frequency and their quantitative anatomical features. The quantity and quality of DNA measured at A260/280 ratio using nanodrop spectrophotometer were 29.1 ng/μL and 1.74 ng/μL for I. doka, respectively, while the I. tomentosa concentration and purity were 71.1 ng/μL and 1.85 ng/μL, respectively. Agarose gel electrophoresis revealed two DNA bands with 700 bp (rbcl) and 600 bp (ITS). The sequence analysis revealed maximum identity with National Centre for Biotechnology Information (NCBI) GeneBank Isoberlinia species. Evolutionary analysis supported the monophyletic origin of the genus Isoberlinia. The morphological and anatomical characters of I. doka and I. tomentosa leaves have provided a significant taxonomy tool for proper authentication of this plant.Conclusion: The findings ascertained that ITS and rbcl served as an improved and efficient tool for species identification of these studied species and could serve as potential DNA barcodes for these taxa.Contribution: This article suggests that further studies the on screening of these plants, for various pharmacological potentials, might be useful for new drug development.
背景:Isoberlinia (Craib和Stapf)是一个具有很高经济和药理价值的属。目的:建立杜鹃和毛蕊花叶片的形态、解剖和分子特征，为鉴定提供依据。背景:多卡和托曼托萨的叶子产自尼日利亚卡杜纳州的Shika。方法:按标准程序进行形态学和解剖学鉴定，采用核酮糖-1,5-二磷酸羧化酶(rbcl)基因和内转录间隔段(ITS) DNA条形码区域进行分子鉴定。结果:形态学研究显示两种植物的特征相似，除了杜鹃的叶片有光泽和毛毛莲的背面由于毛状体的存在而粗糙。在表皮特征、气孔指数、气孔频率、毛状体有无、毛状体频率及其定量解剖特征等方面均存在差异。采用纳米滴分光光度计测定，在A260/280比下，杜卡菊的DNA含量和质量分别为29.1 ng/μL和1.74 ng/μL，毛毛菊的浓度和纯度分别为71.1 ng/μL和1.85 ng/μL。琼脂糖凝胶电泳显示了700 bp (rbcl)和600 bp (ITS)的两条DNA条带。序列分析显示，该菌株与美国国家生物技术信息中心(National Centre for Biotechnology Information, NCBI)基因库(GeneBank)的Isoberlinia物种高度一致。进化分析支持单系起源。杜鹃和毛蕊花叶片的形态解剖特征为该植物的鉴别提供了重要的分类工具。结论:ITS和rbcl是一种改进的、有效的物种鉴定工具，可作为分类群的DNA条形码。贡献:进一步研究这些具有不同药理潜力的植物的筛选，可能对新药开发有帮助。
{"title":"Morphological, anatomical and molecular characterisation of the leaves of Isoberlinia doka Craib and Stapf and Isoberlinia tomentosa (Harms) Craib and Stapf","authors":"Hadiza Bello, Umar A. Katsayal, Aminu A. Ambi, Yusuf B. Abubakar","doi":"10.4102/jomped.v7i1.150","DOIUrl":"https://doi.org/10.4102/jomped.v7i1.150","url":null,"abstract":"Background: Isoberlinia (Craib and Stapf) is a genus with high economic and pharmacological values.Aim: This study aimed at establishing the morphological, anatomical and molecular characterisation of the leaves of I. doka and I. tomentosa, which were conducted for proper authentication.Setting: The leaves of I. doka and I. tomentosa were obtained from Shika, kaduna State, Nigeria.Method: Morphological and anatomical characters were determined according to standard procedures, while molecular identifications were performed using ribulose-1,5-bisphosphate carboxylase (rbcl) gene and internal transcribed spacer (ITS) DNA barcode’s region.Result: Morphological studies revealed similar features for both species except for the shiny leaves of I. doka and rough abaxial surfaces of I. tomentosa because of the presence of trichomes. Variations were observed in their epidermal features, stomatal index, stomata frequency, presence or absence of trichomes, trichomes frequency and their quantitative anatomical features. The quantity and quality of DNA measured at A260/280 ratio using nanodrop spectrophotometer were 29.1 ng/μL and 1.74 ng/μL for I. doka, respectively, while the I. tomentosa concentration and purity were 71.1 ng/μL and 1.85 ng/μL, respectively. Agarose gel electrophoresis revealed two DNA bands with 700 bp (rbcl) and 600 bp (ITS). The sequence analysis revealed maximum identity with National Centre for Biotechnology Information (NCBI) GeneBank Isoberlinia species. Evolutionary analysis supported the monophyletic origin of the genus Isoberlinia. The morphological and anatomical characters of I. doka and I. tomentosa leaves have provided a significant taxonomy tool for proper authentication of this plant.Conclusion: The findings ascertained that ITS and rbcl served as an improved and efficient tool for species identification of these studied species and could serve as potential DNA barcodes for these taxa.Contribution: This article suggests that further studies the on screening of these plants, for various pharmacological potentials, might be useful for new drug development.","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135837106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christeldah Mkhonto, Vusani Makananise, I. Sagbo, Madonna N. Mashabela, P. Ndhlovu, B. Kubheka, W. Otang-Mbeng
{"title":"UPLC–QTOF/MS tentative identification of phytochemicals from Vernonia amygdalina Delile acetone and ethanol leaf extracts","authors":"Christeldah Mkhonto, Vusani Makananise, I. Sagbo, Madonna N. Mashabela, P. Ndhlovu, B. Kubheka, W. Otang-Mbeng","doi":"10.4102/jomped.v7i1.181","DOIUrl":"https://doi.org/10.4102/jomped.v7i1.181","url":null,"abstract":"","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44946108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Govender, Karishma Singh, R. Coopoosamy, J. Adam
year to year (Khan et al. 2022). Chronic kidney disease rates rise rapidly with age, with prevalence in those aged 75 years and up being twice as high as those aged 65–74 years, and nearly seven times higher than those aged 18–54 years (42%, 21% and 6%, respectively). The prevalence of CKD is generally higher in lower socio-economic groups (14% vs. 8% in higher socio-economic groups) (Khan et al. 2022). Indigenous populations are frequently at a higher risk of CKD than nonindigenous populations because of their limited access to hospitals and healthcare centres (Herrera-Añazco et al. 2019; Khan et al. 2022). Current therapies using commercially available drugs only delay the progression of CKD, ultimately creating a financial burden on healthcare systems and an expectation of a rise in hospitalisations and treatments. Therefore, poorer countries Background: Chronic kidney disease (CKD) is a debilitating condition that is becoming more common around the world, as well as a financial and social burden on healthcare systems. If not treated with kidney replacement therapies, kidney failure, the final stage of CKD, can be fatal. Chronic kidney disease patients are now seeking the use of alternative remedies, including medicinal plants, as the primary source of healthcare. Aim: This review aimed to evaluate the use of medicinal plants in the treatment of CKD and other associated kidney diseases in South Africa. Method: This article summarises previous research (2010–2021) on the impact of traditional plant-based medicine in CKD treatment and identifies the context between traditional and conventional medicines. Various scientific databases were used to source key literature. Results: The findings of this study revealed 10 medicinal plant species from nine different botanical families that are commonly used for the treatment of CKD and other kidney-related diseases in South Africa. In addition, the study demonstrated that despite medicinal plants having toxic impacts, they were still the preferred choice of medication for CKD, especially in developing countries. Conclusion: It is crucial to validate the balance between the risks and benefits of medicinal plants in CKD treatment to further enhance the credibility of medical plants in drug development. Contribution: This study contributes to the existing knowledge of medicinal plants used in CKD treatment primarily in South Africa.
{"title":"Identification of medicinal plants used for chronic kidney disease: An update of reported literature in South Africa","authors":"S. Govender, Karishma Singh, R. Coopoosamy, J. Adam","doi":"10.4102/jomped.v7i1.182","DOIUrl":"https://doi.org/10.4102/jomped.v7i1.182","url":null,"abstract":"year to year (Khan et al. 2022). Chronic kidney disease rates rise rapidly with age, with prevalence in those aged 75 years and up being twice as high as those aged 65–74 years, and nearly seven times higher than those aged 18–54 years (42%, 21% and 6%, respectively). The prevalence of CKD is generally higher in lower socio-economic groups (14% vs. 8% in higher socio-economic groups) (Khan et al. 2022). Indigenous populations are frequently at a higher risk of CKD than nonindigenous populations because of their limited access to hospitals and healthcare centres (Herrera-Añazco et al. 2019; Khan et al. 2022). Current therapies using commercially available drugs only delay the progression of CKD, ultimately creating a financial burden on healthcare systems and an expectation of a rise in hospitalisations and treatments. Therefore, poorer countries Background: Chronic kidney disease (CKD) is a debilitating condition that is becoming more common around the world, as well as a financial and social burden on healthcare systems. If not treated with kidney replacement therapies, kidney failure, the final stage of CKD, can be fatal. Chronic kidney disease patients are now seeking the use of alternative remedies, including medicinal plants, as the primary source of healthcare. Aim: This review aimed to evaluate the use of medicinal plants in the treatment of CKD and other associated kidney diseases in South Africa. Method: This article summarises previous research (2010–2021) on the impact of traditional plant-based medicine in CKD treatment and identifies the context between traditional and conventional medicines. Various scientific databases were used to source key literature. Results: The findings of this study revealed 10 medicinal plant species from nine different botanical families that are commonly used for the treatment of CKD and other kidney-related diseases in South Africa. In addition, the study demonstrated that despite medicinal plants having toxic impacts, they were still the preferred choice of medication for CKD, especially in developing countries. Conclusion: It is crucial to validate the balance between the risks and benefits of medicinal plants in CKD treatment to further enhance the credibility of medical plants in drug development. Contribution: This study contributes to the existing knowledge of medicinal plants used in CKD treatment primarily in South Africa.","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43203526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ndou et al. 2019; Sewani-Rusike & Mammen 2014; Spier 2014; Rasethe, Semenya & Maroyi 2019) have extended their supply-side analyses to include the investigation of some market aspects. However, these studies did not investigate possible ways of extending the industry’s product extension and market expansion. The African medicinal plants industry made a significant leap forward in the mid-nineties when popular indigenous medicinal plants were commercialised. This enabled the tackling of product quality, safety and efficacy concerns which formed some of the biggest bottlenecks to the industry’s growth (Asong et al. 2019; Van Wyk 2011). Various industry experts (e.g. Makunga, Philander & Background: The demand for African wormwood and Cancer bush has surged as modern healthcare products have provided limited solutions for the ailments they treat. Moreover, there has been an increase in younger consumers of these medicinal plants, who expect lower-priced products which have a ‘polished look’ that is similar to over-the-counter medicinal products. Aim: This study investigates the need to introduce lower-priced capsules to meet these changes in consumer product preferences. Setting: The study was conducted in the city of Mbombela. This is a city that has a rich heritage in indigenous medicinal plant use but has the absence of a large informal market for their sale. Methods: A willingness-to-pay analysis was conducted. It utilised survey data that was collected from 105 university students. Results: The study found that there were two market segments split with a ratio of about 3:1 between those willing to pay a price similar to a conventional product in the lower price range and those not willing. However, the market potential for introducing a lower-priced product was only found in the Cancer bush market, where respondents were willing to procure the product at a discounted price, as opposed to the African wormwood market, where some respondents were not willing to part with any money at all. Conclusion: The study concludes that there is potential for lucrative market diversification if the industry introduces lower-priced capsules for Cancer bush. Contribution: The study provides insights into the possible areas of market development in the African indigenous medicines market.
{"title":"The willingness to pay for African wormwood and Cancer bush capsules among youths in Mbombela, South Africa","authors":"Nobuhle P. Nsibanyoni, C. Tsvakirai, T. Makgopa","doi":"10.4102/jomped.v7i1.173","DOIUrl":"https://doi.org/10.4102/jomped.v7i1.173","url":null,"abstract":"Ndou et al. 2019; Sewani-Rusike & Mammen 2014; Spier 2014; Rasethe, Semenya & Maroyi 2019) have extended their supply-side analyses to include the investigation of some market aspects. However, these studies did not investigate possible ways of extending the industry’s product extension and market expansion. The African medicinal plants industry made a significant leap forward in the mid-nineties when popular indigenous medicinal plants were commercialised. This enabled the tackling of product quality, safety and efficacy concerns which formed some of the biggest bottlenecks to the industry’s growth (Asong et al. 2019; Van Wyk 2011). Various industry experts (e.g. Makunga, Philander & Background: The demand for African wormwood and Cancer bush has surged as modern healthcare products have provided limited solutions for the ailments they treat. Moreover, there has been an increase in younger consumers of these medicinal plants, who expect lower-priced products which have a ‘polished look’ that is similar to over-the-counter medicinal products. Aim: This study investigates the need to introduce lower-priced capsules to meet these changes in consumer product preferences. Setting: The study was conducted in the city of Mbombela. This is a city that has a rich heritage in indigenous medicinal plant use but has the absence of a large informal market for their sale. Methods: A willingness-to-pay analysis was conducted. It utilised survey data that was collected from 105 university students. Results: The study found that there were two market segments split with a ratio of about 3:1 between those willing to pay a price similar to a conventional product in the lower price range and those not willing. However, the market potential for introducing a lower-priced product was only found in the Cancer bush market, where respondents were willing to procure the product at a discounted price, as opposed to the African wormwood market, where some respondents were not willing to part with any money at all. Conclusion: The study concludes that there is potential for lucrative market diversification if the industry introduces lower-priced capsules for Cancer bush. Contribution: The study provides insights into the possible areas of market development in the African indigenous medicines market.","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46375562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ranganai Chidembo, W. Ndlovu, M. Mwale, O. Obadire, J. Francis
{"title":"Opportunities and challenges in the commercialisation of medicinal plants used in village chicken’s health management","authors":"Ranganai Chidembo, W. Ndlovu, M. Mwale, O. Obadire, J. Francis","doi":"10.4102/jomped.v7i1.175","DOIUrl":"https://doi.org/10.4102/jomped.v7i1.175","url":null,"abstract":"","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49586583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sipho Goge, Karishma Singh, L. V. Komoreng, R. Coopoosamy
{"title":"Pytochemical profile of Aloe ferox Mill. across different regions within South Africa","authors":"Sipho Goge, Karishma Singh, L. V. Komoreng, R. Coopoosamy","doi":"10.4102/jomped.v7i1.178","DOIUrl":"https://doi.org/10.4102/jomped.v7i1.178","url":null,"abstract":"","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44075827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：