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Cucurbitaceae species used as traditional medicine in West Africa 在西非用作传统药物的葫芦科植物
Q4 Economics, Econometrics and Finance Pub Date : 2022-11-29 DOI: 10.4102/jomped.v6i1.163
O. O. Fajinmi, O. O. Olarewaju, G. Arthur, K. Naidoo, R. Coopoosamy
Background: The use of some Cucurbitaceae species for the treatment of diseases is an ancient practice in traditional medicine systems in Africa and the cucurbitacins among others have been reported to be responsible for most of these healing activities.Aim: This review discusses the relevance of Cucurbitaceae species in traditional medicine in some west African countries.Methods: A literature search was conducted on electronic databases such as Google Books, Google Scholar, Scopus and Web of Science. The search involved the use of several terms and free text words which include ‘Cucurbitaceae species in West Africa traditional medicine’; ‘medicinal plants of the Cucurbitaceae family used to treat diseases in west African communities’.Results: Several Cucurbitaceae species are used in the region either in similar ways or different ways for the treatment of different diseases. The leaves are the most utilised plant parts and decoctions are the most common method of preparation. From this study, 18 species of Cucurbitaceae used for medicinal purposes were reviewed from Nigeria; 4 from Benin, Ghana, Côte d’Ivoire and Mali, respectively; 1 from Togo; 5 from Senegal; 9 from Cameroon and 3 from Gabon and Burkina Faso, respectively. Momordica charantia and Momordica balsamina are often utilised for abortion in some west African countries. Momordica species and Lagenaria breviflora are utilised to treat diabetes, cough related to respiratory infections and viral infections such as measles and chickenpoxConclusions: In-depth research into these plants could help to develop a natural, novel cure for diabetes and coronavirus (COVID-19) and effective, cheap contraceptive.Contribution: This review highlights the significant role of Cucurbitaceae species in the treatment of a wide range of diseases and health issues in the WestAfrican traditional medicine system. The information provided could be used as a guide by research scientists for the formulation of natural products to cure a variety of diseases.
背景:在非洲的传统医学系统中,使用一些葫芦科植物治疗疾病是一种古老的做法,据报道,葫芦素等植物具有大部分的治疗作用。目的:综述了葫芦科植物在西非一些国家传统医学中的应用。方法:在谷歌Books、谷歌Scholar、Scopus、Web of Science等电子数据库中进行文献检索。搜索涉及使用几个术语和自由文本词,其中包括“西非传统医学中的葫芦科物种”;“葫芦科药用植物,用于治疗西非社区的疾病”。结果:几种葫芦科植物在该地区以相似或不同的方式用于治疗不同的疾病。叶子是最常用的植物部位,而煎煮是最常用的制备方法。综述了尼日利亚药用葫芦科植物18种;贝宁、加纳、Côte科特迪瓦和马里各4名;多哥1人;塞内加尔5人;喀麦隆9人,加蓬和布基纳法索3人。在一些西非国家,苦瓜和苦瓜经常被用于堕胎。苦瓜和短花lagenaria breviflora被用于治疗糖尿病、与呼吸道感染相关的咳嗽以及麻疹和水痘等病毒感染。结论:对这些植物的深入研究有助于开发一种天然的、新型的治疗糖尿病和冠状病毒(COVID-19)的方法,以及有效、廉价的避孕方法。贡献:本文综述了葫芦科植物在西非传统医学系统中治疗多种疾病和健康问题的重要作用。所提供的信息可作为研究科学家制定天然产品以治疗各种疾病的指南。
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引用次数: 0
Antibacterial activities and biosynthesis of nanoparticles using hemp extracts 大麻提取物的抗菌活性及纳米颗粒的生物合成
Q4 Economics, Econometrics and Finance Pub Date : 2022-10-27 DOI: 10.4102/jomped.v6i1.160
Karishma Singh, R. Coopoosamy, K. Naidoo, J. Adam
Background: The use of plants in the biosynthesis of nanoparticles is a fast-growing technique and has gained much interest from researchers over the years.Aim: This study reported the utilisation of leaf extracts of Cannabis sativa L. (hemp) for the biosynthesis of silver nanoparticles (AgNPs).Methods: In this study, techniques such as transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) microanalysis and Fourier transform infrared (FT-IR) were carried out for the synthesis and characterisation of nanoparticles. The antibacterial efficacy of the synthesised nanoparticles was evaluated by using the agar diffusion and macrobroth dilution methods. The antibacterial properties of the biosynthesised AgNPs were evaluated against both Gram-negative and Gram-positive bacteria.Results: The formation of AgNPs was confirmed by colour change in plant extracts and further characterised by Ultraviolet-visible (UV-Vis) spectrophotometry TEM, SEM, EDX and FT-IR analyses. Fourier transform infrared analysis revealed the efficient capping and stabilisation properties of these particles and the nature of the capping agent. Silver nanoparticles prepared from leaf extracts showed effective antibacterial activity against Escherichia coli.Conclusion: Biosynthesised AgNPs showed a broad-spectrum antimicrobial susceptibility range and therefore represent promising antimicrobial agents. This is the first reported study for hemp leaf extracts and contributes to the environmentally friendly and cost-effective technique of biosynthesising nanoparticles for drug development.Contribution: This study contributes to the current medicinal properties of cannabis. Furthermore, it reflects that cannabis can also be utilized at a nanoscale with effective antibacterial efficacy.
背景:利用植物进行纳米颗粒的生物合成是一项快速发展的技术,近年来引起了研究人员的极大兴趣。目的:本研究报道了利用大麻叶提取物生物合成纳米银(AgNPs)。方法:采用透射电子显微镜(TEM)、扫描电子显微镜(SEM)、能量色散x射线(EDX)显微分析和傅里叶变换红外(FT-IR)等技术对纳米颗粒的合成和表征进行了研究。采用琼脂扩散法和大培养液稀释法对合成的纳米颗粒进行抑菌效果评价。生物合成的AgNPs对革兰氏阴性菌和革兰氏阳性菌的抗菌性能进行了评估。结果:通过植物提取物的颜色变化证实了AgNPs的形成,并通过紫外可见分光光度(UV-Vis)、透射电镜(TEM)、扫描电镜(SEM)、EDX和傅里叶变换红外光谱(FT-IR)分析对其进行了表征。傅里叶变换红外分析揭示了这些颗粒的有效封盖和稳定性能以及封盖剂的性质。叶提取物制备的纳米银对大肠杆菌具有良好的抑菌活性。结论:生物合成的AgNPs具有广谱的抗菌敏感性,是一种很有前景的抗菌药物。这是首次报道大麻叶提取物的研究,并有助于环境友好和具有成本效益的生物合成纳米颗粒技术用于药物开发。贡献:本研究有助于大麻目前的药用特性。此外,这反映了大麻也可以在纳米尺度上利用,具有有效的抗菌功效。
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引用次数: 0
Green tea (Camellia sinensis) aqueous extract improved human spermatozoa functions in vitro 绿茶水提取物改善体外人精子功能
Q4 Economics, Econometrics and Finance Pub Date : 2022-10-26 DOI: 10.4102/jomped.v6i1.166
Mmaphulane A. Setumo, Solomon Sr Choma, R. Henkel, C. Opuwari
Background: Idiopathic causes of infertility is associated with oxidative stress. Antioxidants are known to scavenge the excessive production of reactive oxygen species (ROS). Green tea (Camellia sinensis) contains polyphenols that enhance its antioxidant potential.Aim: This study focused on the impact of aqueous green tea extract on normozoospermic human spermatozoa.Setting: Department of Medical Biosciences, University of the Western Cape (UWC), South Africa.Methods: Semen samples obtained using masturbation method following three to five days of sexual abstinence from consenting men (n = 59) at the University of the Western Cape (UWC) were liquefied and analysed. Normozoospermic samples were selected according to the World Health Organization (WHO) 5th guideline. Thereafter, semen samples (7.5 × 106 /mL) were washed in human tubular fluid (HTF; 10 min at 300 ×g) and exposed to aqueous extracts of green tea (0 μg/mL, 0.4 μg/mL, 4 μg/mL, 40 μg/mL, 405 μg/mL) for 1 h with various sperm parameters analyzed. Human tubular fluid supplemented with bovine serum albumin (HTF-BSA; 10%) served as control.Results: Sperm motility, reactive oxygen species production, across some reaction and deoxyribonucleic acid (DNA) fragmentation decreased significantly, particularly at the highest concentration (405 μg/mL; p 0.001). A substantial increase in the percentage of viable spermatozoa and those with intact mitochondrial membrane potential (MMP) were observed (p 0.001).Conclusion: Aqueous extract of green tea prolonged sperm viability and MMP while reducing sperm intracellular ROS production, capacitation and across some reaction and DNA fragmentation, and may be attributed to its antioxidant potential. However, a high concentration of the extract appears to be detrimental to the functioning of human spermatozoa.
背景:不孕的特发性原因与氧化应激有关。众所周知,抗氧化剂可以清除过量产生的活性氧(ROS)。绿茶(山茶)含有多酚,可以增强其抗氧化能力。目的:研究绿茶水提取物对正常精子的影响。背景:南非西开普大学医学生物科学系。根据世界卫生组织(世界卫生组织)第5号指南选择Normozoospermic样本。然后,精液样品(7.5×106/mL)在人管液(HTF;300×g)中洗涤10分钟,并暴露于绿茶水提取物(0μg/mL、0.4μg/mL,4μg/mL和40μg/mL以及405μg/mL)中1小时,分析各种精子参数。补充有牛血清白蛋白(HTF-BSA;10%)的人管液用作对照。结果:精子活力、活性氧生成、跨某些反应和脱氧核糖核酸(DNA)断裂显著下降,特别是在最高浓度(405μg/mL;p 0.001)下。观察到活精子和线粒体膜电位(MMP)完整精子的百分比显著增加(p 0.001)。结论:绿茶水提取物延长了精子活力和MMP,同时减少了精子细胞内ROS的产生、获能以及一些反应和DNA片段,并且可能归因于其抗氧化潜力。然而,高浓度的提取物似乎对人类精子的功能有害。
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引用次数: 1
A review of the medicinal plants with immune-boosting potential 具有增强免疫潜力的药用植物研究进展
Q4 Economics, Econometrics and Finance Pub Date : 2022-09-27 DOI: 10.4102/jomped.v6i1.158
O. O. Olarewaju, O. O. Fajinmi, K. Naidoo, G. Arthur, R. Coopoosamy
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引用次数: 2
South African medicinal plants screened against Pseudomonas aeruginosa 筛选抗铜绿假单胞菌的南非药用植物
Q4 Economics, Econometrics and Finance Pub Date : 2022-08-29 DOI: 10.4102/jomped.v6i1.153
M. Vambe, R. Coopoosamy, K. Naidoo, G. Arthur
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引用次数: 0
Morphological, anatomical and molecular characterisation of the leaves of Isoberlinia doka Craib and Stapf and Isoberlinia tomentosa (Harms) Craib and Stapf doka Craib和Stapf和绒毛异伯兰(Harms)Craib和Stapf叶片的形态、解剖和分子特征
Q4 Economics, Econometrics and Finance Pub Date : 2022-07-15 DOI: 10.4102/jomped.v6i1.150
H. Bello, U. A. Katsayal, A. A. Ambi, Yusuf B. Abubakar
Background: Isoberlinia (Craib and Stapf) is a genus with high economic and pharmacological values.Aim: This study aimed at establishing the morphological, anatomical and molecular characterisation of the leaves of I. doka and I. tomentosa, which were conducted for proper authentication.Setting: The leaves of I. doka and I. tomentosa were obtained from Shika, kaduna State, Nigeria.Method: Morphological and anatomical characters were determined according to standard procedures, while molecular identifications were performed using ribulose-1,5-bisphosphate carboxylase (rbcl) gene and internal transcribed spacer (ITS) DNA barcode’s region.Result: Morphological studies revealed similar features for both species except for the shiny leaves of I. doka and rough abaxial surfaces of I. tomentosa because of the presence of trichomes. Variations were observed in their epidermal features, stomatal index, stomata frequency, presence or absence of trichomes, trichomes frequency and their quantitative anatomical features. The quantity and quality of DNA measured at A260/280 ratio using nanodrop spectrophotometer were 29.1 ng/μL and 1.74 ng/μL for I. doka, respectively, while the I. tomentosa concentration and purity were 71.1 ng/μL and 1.85 ng/μL, respectively. Agarose gel electrophoresis revealed two DNA bands with 700 bp (rbcl) and 600 bp (ITS). The sequence analysis revealed maximum identity with National Centre for Biotechnology Information (NCBI) GeneBank Isoberlinia species. Evolutionary analysis supported the monophyletic origin of the genus Isoberlinia. The morphological and anatomical characters of I. doka and I. tomentosa leaves have provided a significant taxonomy tool for proper authentication of this plant.Conclusion: The findings ascertained that ITS and rbcl served as an improved and efficient tool for species identification of these studied species and could serve as potential DNA barcodes for these taxa.Contribution: This article suggests that further studies the on screening of these plants, for various pharmacological potentials, might be useful for new drug development.
背景:Isoberlinia属(Craib和Stapf)是一个具有较高经济和药理价值的属。目的:本研究旨在建立多卡和毛白杨叶片的形态、解剖和分子特征,以便于鉴定。背景:从尼日利亚卡杜纳州的希卡获得了多卡和毛白杨的叶片。方法:按照标准程序测定其形态和解剖特征,并利用核酮糖-1,5-二磷酸羧化酶(rbcl)基因和内部转录间隔区(ITS)DNA条形码区进行分子鉴定。结果:形态学研究显示,两个物种具有相似的特征,不同之处在于多卡毛白杨的叶片有光泽,毛白杨的背面粗糙,因为存在毛状体。观察到它们的表皮特征、气孔指数、气孔频率、有无毛状体、毛状体频率及其数量解剖特征的变化。用纳米液滴分光光度计在A260/280比例下测得的doka的DNA数量和质量分别为29.1和1.74纳克/μL,而毛白杨的浓度和纯度分别为71.1和1.85纳克/μL。琼脂糖凝胶电泳显示两条DNA带,分别为700bp(rbcl)和600bp(ITS)。序列分析揭示了与国家生物技术信息中心(NCBI)GeneBank Isoberlinia物种的最大同一性。进化分析支持Isoberlinia属的单系起源。多卡和毛叶的形态和解剖特征为正确鉴定该植物提供了重要的分类学工具。结论:ITS和rbcl是一种改进和有效的物种鉴定工具,可以作为这些分类群的潜在DNA条形码。贡献:这篇文章表明,进一步研究这些植物的各种药理潜力,可能有助于新药的开发。
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引用次数: 0
A review of the role of the Cucurbitaceae family in food security in West Africa 葫芦科植物在西非粮食安全中的作用综述
Q4 Economics, Econometrics and Finance Pub Date : 2022-06-21 DOI: 10.4102/jomped.v6i1.155
O. O. Fajinmi, O. O. Olarewaju, G. Arthur, K. Naidoo, R. Coopoosamy
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引用次数: 0
Sociocultural relevance of the bottle gourd and selected species of Cucurbitaceae family in West Africa 西非葫芦和葫芦科植物的社会文化相关性
Q4 Economics, Econometrics and Finance Pub Date : 2022-06-14 DOI: 10.4102/jomped.v6i1.139
O. O. Fajinmi, O. O. Olarewaju, G. Arthur, R. Coopoosamy, K. Naidoo
{"title":"Sociocultural relevance of the bottle gourd and selected species of Cucurbitaceae family in West Africa","authors":"O. O. Fajinmi, O. O. Olarewaju, G. Arthur, R. Coopoosamy, K. Naidoo","doi":"10.4102/jomped.v6i1.139","DOIUrl":"https://doi.org/10.4102/jomped.v6i1.139","url":null,"abstract":"","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49593033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemical composition and chemical profiling of extracts of Cordia grandicalyx 山茱萸提取物的植物化学成分及化学特征分析
Q4 Economics, Econometrics and Finance Pub Date : 2022-06-09 DOI: 10.4102/jomped.v6i1.149
Mildred A. Chauke, M. Mogale, L. Mdee, L. J. Shai
{"title":"Phytochemical composition and chemical profiling of extracts of Cordia grandicalyx","authors":"Mildred A. Chauke, M. Mogale, L. Mdee, L. J. Shai","doi":"10.4102/jomped.v6i1.149","DOIUrl":"https://doi.org/10.4102/jomped.v6i1.149","url":null,"abstract":"","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43033977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gibberellic acid influences growth indices and biochemical parameters in micropropagated Ocimum gratissimum L. explants 赤霉素酸对微繁羊草外植体生长指标和生化指标的影响
Q4 Economics, Econometrics and Finance Pub Date : 2022-05-17 DOI: 10.4102/jomped.v6i1.154
Muyibat M. Olaitan, G. Mangse, Chukwuma C. Ogbaga, T. Uthman
{"title":"Gibberellic acid influences growth indices and biochemical parameters in micropropagated Ocimum gratissimum L. explants","authors":"Muyibat M. Olaitan, G. Mangse, Chukwuma C. Ogbaga, T. Uthman","doi":"10.4102/jomped.v6i1.154","DOIUrl":"https://doi.org/10.4102/jomped.v6i1.154","url":null,"abstract":"","PeriodicalId":16345,"journal":{"name":"Journal of Medicinal Plants for Economic Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42083539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Journal of Medicinal Plants for Economic Development
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