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Association between Native Language and Adherence to the Treatment of Chronic Diseases: Arterial Hypertension and Diabetes Mellitus in the Older Adult in Peru 母语与慢性病治疗依从性的关系:秘鲁老年人的动脉高血压和糖尿病
Pub Date : 2021-10-26 DOI: 10.26655/jmchemsci.2022.1.7
Emma Janet Luna Arriola
Objectives: To establish whether there is an association between adherence to treatment and the patient's language.Design: The article presents an analytical cross-sectional design.Data Sources: The study used the 2019 Demographic and Family Health Survey (ENDES) in 33,760 homes throughout Peru, carried out by the National Institute of Statistics and Informatics (INEI). Due to the nature of our population, a sample size calculation was performed using the frequency of the expected outcome.Review Methods: A bibliography search was carried out in PUBMED, GoogleSchoolar, and Redalyc.Results: In the regression analysis, we observed that in the crude model the risk of having non-adherence to treatment in people with a native mother tongue was 1.607, the risk of older adults with a mother tongue Spanish. Regarding the model adjusted by the epidemiological model, the prevalence of risk was 1.60; this association was shown to be statistically significant.Conclusion: If the patient presents a language different from that of the treating physician, it is more likely that the treatment will be missed.
目的:确定治疗依从性与患者语言之间是否存在关联。设计:本文提出了一个分析性的横断面设计。数据来源:该研究使用了由国家统计和信息学研究所(INEI)在秘鲁全国33,760个家庭中进行的2019年人口和家庭健康调查(ENDES)。由于我们人口的性质,使用预期结果的频率进行样本大小计算。综述方法:在PUBMED、GoogleSchoolar和Redalyc中进行文献检索。结果:在回归分析中,我们观察到在粗模型中,母语为西班牙语的老年人不坚持治疗的风险为1.607,母语为西班牙语的老年人风险为1.607。经流行病学模型调整后的模型,风险患病率为1.60;这种关联在统计上是显著的。结论:如果患者的语言与主治医生的语言不同,则更有可能错过治疗。
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引用次数: 0
The Role of Garlic Oil in Improving Disturbances in Blood Parameters Caused by Zinc Oxide Nanoparticles 大蒜油在改善氧化锌纳米颗粒引起的血液参数紊乱中的作用
Pub Date : 2021-10-26 DOI: 10.26655/jmchemsci.2022.1.9
J. Mahmoud, O. A. Ghareeb, Y. H. Mahmood
Industrial applications of zinc oxide nanoparticles (ZnO-NPs) are increasing because of their unique features, such as their widespread use in cosmetics as well as sun screens. The potential harmful effects of ZnO-NPs need to be investigated further. The purpose of this research is to examine the prophylactic effect of garlic oil on some hematological parameters altered by zinc oxide nanoparticles (ZnO-NPs) of adult male rats. This experiment was conducted on thirty-six male rats fall into 4 packs of six animals each. CON is the control group of healthy rats. ZnO-NPs group received 200 mg/kg zinc oxide nanoparticles, while the ZnO-NPs +GO group intoxicated rats received 100 ml/kg garlic oil, and GO group rats received only 100 ml/kg garlic oil. Study duration was 15 days. After the experimentation, rats were sacrificed and the levels of hematological parameters were evaluated, which included erythrocytes count, hemoglobin level, leukocytes count, and platelet count. The results of this study showed that zinc oxide led to significant changes in blood parameters, and when combined with garlic oil, hematological toxicity was improved. In conclusion, the hematological toxicity of ZnO-NPs was noticeable; however, the use of doses of garlic oil reduced this toxic effect.
氧化锌纳米颗粒(ZnO-NPs)由于其独特的特性,如在化妆品和防晒霜中的广泛应用,其工业应用正在增加。ZnO-NPs的潜在有害影响需要进一步研究。本研究旨在探讨大蒜油对氧化锌纳米颗粒(ZnO-NPs)改变的成年雄性大鼠血液参数的预防作用。本实验以36只雄性大鼠为实验对象,分为4组,每组6只。CON为健康大鼠的对照组。ZnO-NPs组给予200 mg/kg氧化锌纳米颗粒,ZnO-NPs +氧化石墨烯组中毒大鼠给予100 ml/kg大蒜油,氧化石墨烯组大鼠仅给予100 ml/kg大蒜油。研究时间为15天。实验结束后,处死大鼠,测定血液学指标,包括红细胞计数、血红蛋白计数、白细胞计数、血小板计数。本研究结果表明,氧化锌导致血液参数发生显著变化,与大蒜油联合使用时,血液毒性得到改善。结果表明,ZnO-NPs具有明显的血液学毒性;然而,大蒜油的使用减少了这种毒性作用。
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引用次数: 2
Work Life Balance of Health Care Workers in the New Normal: A Review of Literature 新常态下医护人员的工作生活平衡:文献综述
Pub Date : 2021-10-26 DOI: 10.26655/jmchemsci.2022.1.6
Tapaswini Pattnaik, S. Samanta, Jitendra Mohanty
Life of a health care worker is very different compared with any other professional. This is distinct not from the perspective of an overwhelming level of personal and professional accomplishment, but from the huge amount of psychological stress and anxiety involved in it. Earlier studies show that health workers, particularly medical practitioners, are vulnerable to mental health developments. Furthermore, workplace stress has been related to emotional exhaustion, which can result in a lack of enthusiasm for work, feelings of powerlessness, depression, and defeat. Emotional factors inherent to the job, responsibilities related to patient needs, feeling of being overburdened, organizational responsibilities, and issues related to working relationships and career growth are commonly identified as occupational stressors among medical professionals. Emotional fatigue is commonly referred to as burnout among professionals. The present paper is an initiative to understand the various dynamics of work life balance during pandemic and to undertake the empirical study on the topic. In this regard, the authors undertook the secondary sources for preparing the paper. The present initiative will be a value addition to the existing literature.
卫生保健工作者的生活与任何其他专业人员都大不相同。这不是从个人和职业成就的压倒性水平的角度来看,而是从与之相关的巨大心理压力和焦虑的角度来看。早期的研究表明,卫生工作者,特别是医生,容易受到心理健康发展的影响。此外,工作压力与情绪疲惫有关,这会导致对工作缺乏热情,感到无能为力,沮丧和失败。工作中固有的情感因素、与病人需求相关的责任、负担过重的感觉、组织责任以及与工作关系和职业发展相关的问题通常被认为是医疗专业人员的职业压力源。在专业人士中,情绪疲劳通常被称为倦怠。本论文旨在了解流行病期间工作与生活平衡的各种动态,并对该主题进行实证研究。在这方面,作者承担了编写论文的二手资料。目前的倡议将是对现有文献的补充。
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引用次数: 3
Phytochemical Composition and the Evaluation of Antioxidant Activity of Methanolic Extract and Essential Oil of Satureja Rechingeri Extract and Essential Oil 红柳甲醇提取物和精油的植物化学成分及抗氧化活性评价
Pub Date : 2021-10-26 DOI: 10.26655/jmchemsci.2022.1.8
Malieh Noormohammadi, S. Shamaei
Aromatic herbs have special applications in pharmacy and cosmetics due to their secondary and medicinal compounds. For this reason, aromatic plants are especially suitable for multifunctional sustainable crop models. The main purpose of this study was to evaluate of chemical compounds of essential oils in different organs of Satureja rechingeri belongs to Asteraceae family. The plant was collected and then dried in the shade for a month at room temperature. Essential oils were extracted by hydro distillation and were analyzed by GC-MS apparatus. The results of this study showed that the different organs can be effective in main compounds of essential oils. Antioxidant efficacy of extract and essential oil of S. rechingeri was determined by DPPH method. The most important compound identified in of S. rechingeri essential oil was carvacrol, which was found to be 83.90%, 81.11% and 95.70% in the leaves, flowers and stems of this plant, respectively. The results of the present study showed the antioxidant activity of methanolic extract of the plant. This is probably due to the presence of flavonoid and polyphenolic compounds. Satureja essential oil showed moderate antioxidant activity of S. rechingeri extract had stronger antioxidant effects compared with its essential oil. Therefore, S. rechingeri extract can be useful in food hygiene and medicine.
芳香类草药因其次生和药用化合物而在制药和化妆品中有着特殊的应用。因此,芳香植物特别适合作为多功能可持续作物模式。本研究的主要目的是对菊科红柳不同器官精油的化学成分进行评价。将植物收集起来,然后在阴凉处室温干燥一个月。采用水蒸气蒸馏法提取精油,气相色谱-质谱联用仪进行分析。本研究结果表明,精油的主要化合物对不同脏器均有作用。采用DPPH法测定苦参提取物和挥发油的抗氧化作用。香芹精油中含量最高的化合物为香芹醇,在香芹叶、花和茎中含量分别为83.90%、81.11%和95.70%。本研究结果显示了该植物甲醇提取物的抗氧化活性。这可能是由于黄酮类化合物和多酚化合物的存在。红荆挥发油抗氧化活性中等,红荆提取物的抗氧化作用强于红荆挥发油。因此,红椒提取物在食品卫生和医药方面具有重要的应用价值。
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引用次数: 1
The Association between Serum Ferritin Levels and 25(OH)D Levels in Adult Patients with Transfusion Dependent Thalassemia 输血依赖型地中海贫血成年患者血清铁蛋白水平与25(OH)D水平的关系
Pub Date : 2021-10-25 DOI: 10.26655/jmchemsci.2022.1.5
Muhammad Ivan Jazuli, S. U. Y. Bintoro, S. W. Mudjanarko
Deficiency and insufficiency of 25(OH)D in thalassemia patients are still high even in countries with abundant sun exposure or with vitamin D supplementation. Long term routine blood transfusions in thalassemia patients cause iron overload which is characterized by increase in serum ferritin levels. Liver damage due to iron overload is thought to disrupt synthesis of 25(OH)D in the liver. This study aimed to determine the association between serum ferritin levels and 25(OH)D levels in adult patients with transfusion dependent thalassemia. This was a cross-sectional observational analytic study. The blood sample were collected from adult patients with transfusion dependent thalassemia to measure the levels of serum ferritin using the electrochemiluminescence immunoassay (ECLIA) method and 25(OH)D levels using the chemiluminescence microparticle immunoassay (CMIA) method. There were 45 subjects, 24 males and 21 females with median age of 23 years; duration of transfusions was 16.3 ± 6.2 years. 23 subjects used deferasirox and 22 subjects used deferiprone iron chelator. The median of serum ferritin levels was 4,467 ng/mL and the mean of 25(OH)D levels was 12.69 ± 4.84 ng/mL. There was significantly negative association between serum ferritin levels and 25(OH)D levels (r = - 0.41, p = 0.003). In this study, significantly negative association was found between serum ferritin levels and 25(OH)D levels. High serum ferritin levels may decrease 25(OH)D levels in adult patients with transfusion dependent thalassemia.
即使在阳光充足或补充维生素D的国家,地中海贫血患者25(OH)D缺乏和不足的情况仍然很高。地中海贫血患者长期常规输血导致铁超载,其特征是血清铁蛋白水平升高。铁超载引起的肝损伤被认为会破坏肝脏中25(OH)D的合成。本研究旨在确定输血依赖型地中海贫血成年患者血清铁蛋白水平与25(OH)D水平之间的关系。这是一项横断面观察性分析研究。采用电化学发光免疫分析法(ECLIA)和化学发光微粒免疫分析法(CMIA)分别测定输血依赖性地中海贫血成人患者血清铁蛋白水平和25(OH)D水平。受试者45例,男24例,女21例,中位年龄23岁;输血时间16.3±6.2年。23例使用去铁胺,22例使用去铁螯合剂。血清铁蛋白水平中位数为4467 ng/mL, 25(OH)D水平平均值为12.69±4.84 ng/mL。血清铁蛋白水平与25(OH)D水平呈显著负相关(r = - 0.41, p = 0.003)。本研究发现血清铁蛋白水平与25(OH)D水平呈显著负相关。高血清铁蛋白水平可降低输血依赖型地中海贫血成年患者25(OH)D水平。
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引用次数: 2
Genetic Detection of Some Bacterial Species Associated with Bovine Keratoconjunctivitis Infections in Basra Governorate 巴士拉省牛角膜结膜炎感染相关细菌的遗传检测
Pub Date : 2021-10-24 DOI: 10.26655/jmchemsci.2022.1.3
Nawres N. Jaber, M. H. Sayhood, N. Hadi, Basil A. Abbas, Noor Amjad Kazem
Veterinary chemicals are pharmaceuticals or treatments that are used in cattle to treat or prevent disease, injury, and pests. Livestock survival and productivity would be severely reduced without veterinary drugs, especially for intensively maintained animals like pigs and poultry. Infectious bovine keratoconjunctivitis is a bacterial eye illness of cattle, and there is limited knowledge on the study of bacterium pathogen-contaminated eyes of animals in Basra province. As a result, the purpose of this research was to isolate and classify some bacterial species associated with infection in cattle with keratoconjunctivitis. This study included examination of 120 eye swabs from cows from different regions in the Basra governorate. The current study was carried out from October 2018 to February 2019. Out of 120 cases involved in this study, 30 cases were identified to have keratoconjunctivitis. The results of the study showed that eye infections in cows were mostly unilateral, in one eye (69%), and less than bilateral infections in both eyes (30.9%). Twenty different bacterial isolates were obtained, and the isolated bacteria were identified genetically by 16S rDNA and sequencing as Escherichia coli 40%, Bacillus subtilis 10%, Enterobacter cancer genus 10%, Enterobacter hormaechei 10%, Enterobacter cloacae 15%, and Klebsiella pneumonia 15%.
兽医用化学品是用于治疗或预防疾病、伤害和害虫的药物或治疗方法。如果没有兽药,牲畜的生存和生产力将严重降低,特别是像猪和家禽这样集约化饲养的动物。传染性牛角膜结膜炎是牛的一种细菌性眼病,对巴士拉省受细菌病原体污染的动物眼睛的研究了解有限。因此,本研究的目的是分离和分类一些与牛角膜结膜炎感染相关的细菌种类。这项研究包括对来自巴士拉省不同地区的120头奶牛的眼拭子进行检查。目前的研究是在2018年10月至2019年2月期间进行的。在本研究涉及的120例病例中,有30例被确定为角膜结膜炎。研究结果表明,奶牛的眼部感染多为单侧感染(69%),双侧感染较少(30.9%)。经16S rDNA和测序鉴定,分离出的细菌分别为大肠杆菌40%、枯草芽孢杆菌10%、癌症肠杆菌属10%、霍氏肠杆菌10%、阴沟肠杆菌15%、肺炎克雷伯菌15%。
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引用次数: 0
Primary Treatment of Landfill Leachate Effects on Heavy Metal and Soil Chemical Properties in Kwashe Industrial Area in Duhok Province, Kurdistan Region of Iraq 垃圾渗滤液初级处理对伊拉克杜胡克省夸什工业区重金属和土壤化学性质的影响
Pub Date : 2021-10-21 DOI: 10.26655/jmchemsci.2022.1.1
N. Hassan, M. Umer
Leachate is a major problem created from municipal solid waste (MSW) landfills and is considered the worst source of surface water and groundwater pollution. Kwashe industrial area as one of the most fast developing and polluted industrial area in Kurdistan region with many factories has a large solid waste separation factory that receives approximately 900 tons of municipal solid waste, out of which about 50% is organic kitchen waste. Samples of leachate were randomly collected from different sites downward drain of landfill and treated by aeration and filtration processes over a month. The results revealed that the soil was affected highly by soluble salts like Na and K from landfill; consequently, the electrical conductivity was 6.37(ds/m), 6 folds greater than the acceptable ranges. The primary treatment of landfill leachate by aeration and filtration reduced all heavy metals to acceptable ranges except Fe and Al, which remained relatively high over allowable ranges because the behavior and reaction of heavy metals in leachates is complicated as many acids are formed during the acidogensis of organic waste biodegradation that increases the solubility of these cationic heavy metals. The extractable forms of calcium, magnesium, sodium, potassium, sodium, and lithium are within acceptable ranges, which indicated not being enough to cause a threat in deteriorating soil and environmental chemistry. The results also showed that there was a close correlation between landfill leachate content of heavy metals and soil content affected by this leachate of Zn, Fe, Cu, Al, and Co at (P ≤ 0.01), but the soil downward landfill leachate fortunately did not reach the hazardous limits of their content in heavy metals and also did not exceed the standard ranges in soil.
渗滤液是城市固体垃圾填埋场产生的一个主要问题,被认为是地表水和地下水污染的最严重来源。夸什工业区是库尔德斯坦地区发展最快、污染最严重的工业区之一,有许多工厂,有一个大型固体废物分选厂,每年接收约900吨城市固体废物,其中约50%是有机厨房垃圾。在一个多月的时间里,随机从填埋场下泄的不同地点收集渗滤液样本,并进行曝气和过滤处理。结果表明:填埋土壤受Na、K等可溶性盐的影响较大;因此,电导率为6.37(ds/m),超过可接受范围的6倍。填埋渗滤液的主要处理方法是曝气和过滤,除铁和铝外,所有重金属都降低到可接受的范围内,但铁和铝在允许范围内仍然相对较高,因为重金属在渗滤液中的行为和反应是复杂的,因为有机废物生物降解的酸中毒过程中形成了许多酸,增加了这些阳离子重金属的溶解度。钙、镁、钠、钾、钠和锂的可提取形式在可接受范围内,这表明不足以对日益恶化的土壤和环境化学造成威胁。结果还表明,垃圾渗滤液中重金属含量与受该渗滤液影响的土壤Zn、Fe、Cu、Al和Co含量呈密切相关(P≤0.01),但幸运的是,土壤向下的垃圾渗滤液中重金属含量没有达到危险限值,也没有超过土壤的标准范围。
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引用次数: 1
The Impact of Drug on Heart Problems in Children with a Family-Centered Care Approach 药物对以家庭为中心的儿童心脏问题的影响
Pub Date : 2021-10-12 DOI: 10.26655/jmchemsci.2021.6.14
Jalal Nourmohammadi, H. Behroozfar, Samaneh Mahmoodi, Fereshteh Rajabiniat, N. Sadeghi, Z. Nourmohammadi
The purpose of this study was to investigate the effects of the drug on children and their lifespan by compiling a clinical guide. The comparative method was multi-stage. The statistical population in this study was the people in the focus group and nurses working in the pediatric ward of hospitals affiliated to Mashhad University of Medical Sciences, Shahid Beheshti Medical Sciences of Tehran, Shiraz Medical Sciences, Isfahan Medical Sciences and Birjand Medical Sciences. Convenient and available sampling method was available as many as 100 people. The data collection instrument was a three-part questionnaire, including pre-mortem, in-child and post-mortem care. Responses were calculated using a round scale from inappropriate to appropriate with a score of one to nine. The content validity method was used to confirm the validity of the questionnaire and the round fit method technique was used for checking the reliability. The results of this study provided nurses with appropriate guidance to make more informed decisions regarding the challenges of providing nursing care in the later stages of children's lives and supporting parents and other family members, and to improve the quality-of-service delivery.
本研究的目的是通过编写临床指南来调查药物对儿童及其寿命的影响。采用多阶段比较法。本研究的统计人群为在马什哈德医学科学大学附属医院儿科病房工作的焦点组人员和护士,德黑兰Shahid Beheshti医学科学,设拉子医学科学,伊斯法罕医学科学和Birjand医学科学。方便有效的抽样方法可供多达100人使用。数据收集工具是一份由三部分组成的问卷,包括死前、儿童和死后护理。回答是用从不合适到合适的整数来计算的,得分从1到9。采用内容效度法对问卷的效度进行确认,采用轮合法技术对问卷的信度进行检验。本研究的结果为护士提供了适当的指导,使他们能够在儿童生命后期提供护理和支持父母和其他家庭成员的挑战方面做出更明智的决定,并提高服务质量。
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引用次数: 0
Prevalence of Cognitive Impairment and Its Associated Factors in Elderly Patients under Chronic Hemodialysis Treatment 老年慢性血液透析患者认知功能障碍的患病率及其相关因素
Pub Date : 2021-10-09 DOI: 10.26655/jmchemsci.2021.6.13
Raheleh Alimoradzadeh, Hosna Ranjbar, M. Abbasi, F. Montazer
The present study was a cross-sectional investigation carried out on elderly patients under chronic hemodialysis who referred to Firoozabadi Hospital during 2019- 2020. The study population was 80 patients ≥ 60 years. The patients’ cognitive status was determined using MMSE and MOCA tools. The mean age of the candidate patients was 71.71 ± 6.28 years old. Cognitive function was assessed by MMSE and MoCA tests and the mean score of the MMSE test was 20.05 ± 3.50 with the highest score being 26 and the lowest score being 12. Based on the results, these patients were divided into three groups with normal cognitive ­function, mild cognitive impairment, and severe cognitive impairment. According to the results of the MMSE test, 19 patients (23.75%) had a normal cognitive function and 45 patients (56.25%) had impairment. In other words, the older patients, the lower level of education, the longer duration of hemodialysis, and the patients with a history of diabetes were more susceptible to cognitive impairment. Subsequently, there was a positive correlation between the levels of BUN, creatinine, uric acid, and PTH, which means that the higher level of these variables in patients was related to the higher risk of cognitive impairment. The findings of the present investigation revealed that the cognitive function and the studied variables including age, level of education, history of diabetes, hemodialysis duration, BUN, Creatinine, Uric Acid, PTH, Sodium, and Kt/V had a significant difference in patients undergoing hemodialysis.
本研究是对2019- 2020年在Firoozabadi医院转诊的慢性血液透析老年患者进行的横断面调查。研究人群为80例≥60岁的患者。采用MMSE和MOCA工具测定患者的认知状态。候选患者的平均年龄为71.71±6.28岁。采用MMSE和MoCA测试评估认知功能,MMSE测试平均得分为20.05±3.50分,最高得分为26分,最低得分为12分。根据结果将患者分为认知功能正常组、轻度认知功能障碍组和重度认知功能障碍组。MMSE测试结果显示,19例(23.75%)患者认知功能正常,45例(56.25%)患者认知功能受损。也就是说,年龄越大、受教育程度越低、血液透析时间越长、有糖尿病史的患者更容易发生认知障碍。随后,BUN、肌酐、尿酸、甲状旁腺素水平呈正相关,说明患者这些变量水平越高,认知功能障碍风险越高。本研究结果显示,血液透析患者的认知功能及年龄、文化程度、糖尿病史、血液透析时间、BUN、肌酐、尿酸、甲状旁腺素、钠、Kt/V等研究变量存在显著差异。
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引用次数: 1
Antibacterial Activity of Copper (II) Complexes of Maleic Acid: Thermal Studies, and New Precursors for Preparation of CuO 马来酸铜(II)配合物的抗菌活性:热研究及制备CuO的新前驱体
Pub Date : 2021-10-08 DOI: 10.26655/jmchemsci.2021.6.11
A. D. Khalaji, M. Emami, Navid Mohammadi
In this paper, two copper(II) complexes based on maleic acid ligand, namely [Cu(MA)2(H2O)2] (1) and [-{(H2O)4Cu2}(μ-MA)]n (2) have been synthesized from the reaction of CuCl2 and maleic acid in aqueous solution and characterized by CHN, FT-IR, XRD and TGA. In addition, from the calcination of theses complexes at 600 °C for 3 h in air atmosphere, CuO particles were prepared and characterized by FT-IR, XRD and SEM. Furthermore, antibacterial activity of them were tested against two Gram-positive (S. aureus and B. cereus) and two Gram-negative (E. coli and P. aeruginosa) strains. Results shows that the complexes 1 and 2 exhibit enhanced antibacterial activity than CuO particles.
本文用CuCl2与马来酸在水溶液中反应合成了[Cu(MA)2(H2O)2](1)和[-{(H2O)4Cu2}(μ-MA)]n(2)两个基于马来酸配体的铜(II)配合物,并用CHN、FT-IR、XRD和TGA对其进行了表征。此外,将这些配合物在空气气氛中600℃煅烧3 h,制备了CuO颗粒,并用FT-IR、XRD和SEM对其进行了表征。并对2株革兰氏阳性菌(金黄色葡萄球菌和蜡样芽孢杆菌)和2株革兰氏阴性菌(大肠杆菌和铜绿假单胞菌)进行抑菌活性试验。结果表明,配合物1和2比CuO颗粒具有更强的抗菌活性。
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引用次数: 3
期刊
Journal of Medicinal and Chemical Sciences
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