首页 > 最新文献

Journal of Medicine in the Tropics最新文献

英文 中文
Neonatal outcomes following caesarean section in Aminu Kano Teaching Hospital, Kano, North-west Nigeria 尼日利亚西北部卡诺Aminu Kano教学医院剖宫产后新生儿结局
Pub Date : 2020-07-01 DOI: 10.4103/jomt.jomt_47_19
A. Mohammed, A. Rabiu, Bashir O Yusuf, F. Usman, M. Gambo, Rukayya Sidi, I. Garba, Mujahid Hassan
Background: Type of anaesthesia is believed to have a role in neonatal outcomes at birth. Regional anaesthesia is thought to have a better neonatal outcome. We assessed the APGAR scores of neonates, the effect of anesthetic technique and associations between maternal and neonatal variables. Methods: This was a cross-sectional study conducted from 1st August, 2018, to 31st January, 2019, at Aminu Kano Teaching Hospital. Ethics approval was obtained from College of Health Science Ethics Committee, Bayero University Kano. All consenting pregnant women scheduled for elective or emergency caesarean section within the study period were recruited. Information such as anesthesia delivery interval and neonatal outcomes were recorded on a questionnaire. Data collected were analyzed using SPSS version 22.0. Fisher’s Exact Test was used for categorical data, and the P < 0.05 was considered significant. Results: Sixty-six pregnant women were recruited. The mean age (±SD) of the pregnant women was 29.4±5.58 years. Up to 59 patients (89.4%) received subarachnoid block (SAB). Thirty six (54.5%) were delivered within 10 minutes following administration of anesthesia. Most of the newborns had normal heart rate 65 (98.5%) and Apgar scores at 1st and 5th minutes (51 (77.3%), 62 (93.9%) respectively. Only ASA PS class was found to be statistically associated with neonatal Apgar scores at 5th minutes (Fisher’s Exact Test = 0.039). Conclusion: Subarachnoid block was the main anesthesia type for caesarean section and more than half of the patients were delivered following administration of anesthesia within 10 minutes with excellent neonatal outcomes.
背景:麻醉类型被认为对新生儿出生结局有影响。局部麻醉被认为有更好的新生儿结局。我们评估了新生儿的APGAR评分,麻醉技术的影响以及孕产妇和新生儿变量之间的关系。方法:这是一项横断面研究,于2018年8月1日至2019年1月31日在Aminu Kano教学医院进行。获得卡诺巴耶罗大学健康科学学院伦理委员会的伦理批准。所有在研究期间同意选择或紧急剖腹产的孕妇都被招募。在问卷上记录麻醉分娩间隔和新生儿结局等信息。收集的数据使用SPSS 22.0版进行分析。分类资料采用Fisher精确检验,P < 0.05。结果:招募了66名孕妇。孕妇平均年龄(±SD)为29.4±5.58岁。59例(89.4%)患者接受了蛛网膜下腔阻滞(SAB)治疗。36例(54.5%)在麻醉后10分钟内分娩。多数新生儿心率正常65分(98.5%),第1分钟、第5分钟Apgar评分分别为51分(77.3%)、62分(93.9%)。只有ASA PS等级与新生儿第5分钟Apgar评分有统计学关联(Fisher精确检验= 0.039)。结论:蛛网膜下腔阻滞是剖宫产术的主要麻醉方式,半数以上患儿在麻醉后10分钟内分娩,新生儿结局良好。
{"title":"Neonatal outcomes following caesarean section in Aminu Kano Teaching Hospital, Kano, North-west Nigeria","authors":"A. Mohammed, A. Rabiu, Bashir O Yusuf, F. Usman, M. Gambo, Rukayya Sidi, I. Garba, Mujahid Hassan","doi":"10.4103/jomt.jomt_47_19","DOIUrl":"https://doi.org/10.4103/jomt.jomt_47_19","url":null,"abstract":"Background: Type of anaesthesia is believed to have a role in neonatal outcomes at birth. Regional anaesthesia is thought to have a better neonatal outcome. We assessed the APGAR scores of neonates, the effect of anesthetic technique and associations between maternal and neonatal variables. Methods: This was a cross-sectional study conducted from 1st August, 2018, to 31st January, 2019, at Aminu Kano Teaching Hospital. Ethics approval was obtained from College of Health Science Ethics Committee, Bayero University Kano. All consenting pregnant women scheduled for elective or emergency caesarean section within the study period were recruited. Information such as anesthesia delivery interval and neonatal outcomes were recorded on a questionnaire. Data collected were analyzed using SPSS version 22.0. Fisher’s Exact Test was used for categorical data, and the P < 0.05 was considered significant. Results: Sixty-six pregnant women were recruited. The mean age (±SD) of the pregnant women was 29.4±5.58 years. Up to 59 patients (89.4%) received subarachnoid block (SAB). Thirty six (54.5%) were delivered within 10 minutes following administration of anesthesia. Most of the newborns had normal heart rate 65 (98.5%) and Apgar scores at 1st and 5th minutes (51 (77.3%), 62 (93.9%) respectively. Only ASA PS class was found to be statistically associated with neonatal Apgar scores at 5th minutes (Fisher’s Exact Test = 0.039). Conclusion: Subarachnoid block was the main anesthesia type for caesarean section and more than half of the patients were delivered following administration of anesthesia within 10 minutes with excellent neonatal outcomes.","PeriodicalId":16477,"journal":{"name":"Journal of Medicine in the Tropics","volume":"5 1","pages":"100 - 107"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90962274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pattern of tracheostomy-related complications and its determinants in Kano: a ten-year single institution experience 卡诺气管切开术相关并发症的模式及其决定因素:一个十年单一机构的经验
Pub Date : 2020-07-01 DOI: 10.4103/jomt.jomt_43_19
A. Ajiya
Background: Tracheostomy is the surgical creation of an opening into the trachea. Reported complication rates of tracheostomy are varied and depends on the study design, study population, patients’ follow-up and the definition of the different complications. We reviewed the pattern of tracheostomy-related complications and its determinants. Methods: This study was a 10-year retrospective review of patients who had tracheostomy in the study area between January 2008 to December 2017. Case files of the patients were retrieved, reviewed, and information extracted. Results: Of the 149 patients, the male: female ratio was 3.8:1 with age range of 6 months to 86 years. The peak age group was 1−10 years. Foreign body aspiration and head and neck neoplasia were the two most common admitting diagnoses; 56 (37.6%) and 55 (36.8%) respectively. The most common indication was upper airway obstruction (129, 86.6%). Emergency tracheostomy was most commonly done (126, 84.6%) and majority of the tracheostomies were done under general anaesthesia (101, 67.8%). Trainee ENT surgeons performed the most tracheostomies (108, 72.5%). Surgical decanulation was done for 5 (3.4%) of the patients. The complication and mortality rates were 42.3% and 2.6% respectively. The most common period of complication was early postoperative period (46, 73.0%), and the most common complications were tube blockage and tube displacement (26, 41.3% and 11, 17.5%) respectively. The analyzed variables were not statistically significant determinants of tracheostomy-related complications among the patients. Conclusion: Tracheostomy-related complications are common, usually in the early postoperative period and usually involve blockage or displacement of the tube.
背景:气管切开术是在气管上开一个口的外科手术。报道的气管切开术并发症发生率各不相同,这取决于研究设计、研究人群、患者随访和不同并发症的定义。我们回顾了气管造口术相关并发症的模式及其决定因素。方法:本研究对2008年1月至2017年12月研究区域气管切开术患者进行了10年回顾性分析。检索、回顾患者的病例档案,提取信息。结果:149例患者中,男女比例为3.8:1,年龄6个月~ 86岁。高峰年龄组为1 ~ 10岁。异物吸入和头颈部肿瘤是两种最常见的入院诊断;56人(37.6%),55人(36.8%)。最常见的指征是上气道阻塞(129例,86.6%)。急诊气管切开术最为常见(126例,84.6%),绝大多数气管切开术是在全身麻醉下进行的(101例,67.8%)。实习耳鼻喉外科医生施行气管切开术最多(108,72.5%)。5例(3.4%)患者行手术脱管。并发症和死亡率分别为42.3%和2.6%。并发症以术后早期最为常见(46,73.0%),并发症以管堵和管移位最为常见(分别为26,41.3%和11,17.5%)。分析的变量在患者中没有统计学意义的气管造口相关并发症的决定因素。结论:气管造瘘相关并发症较为常见,多发生在术后早期,多为气管阻塞或移位。
{"title":"Pattern of tracheostomy-related complications and its determinants in Kano: a ten-year single institution experience","authors":"A. Ajiya","doi":"10.4103/jomt.jomt_43_19","DOIUrl":"https://doi.org/10.4103/jomt.jomt_43_19","url":null,"abstract":"Background: Tracheostomy is the surgical creation of an opening into the trachea. Reported complication rates of tracheostomy are varied and depends on the study design, study population, patients’ follow-up and the definition of the different complications. We reviewed the pattern of tracheostomy-related complications and its determinants. Methods: This study was a 10-year retrospective review of patients who had tracheostomy in the study area between January 2008 to December 2017. Case files of the patients were retrieved, reviewed, and information extracted. Results: Of the 149 patients, the male: female ratio was 3.8:1 with age range of 6 months to 86 years. The peak age group was 1−10 years. Foreign body aspiration and head and neck neoplasia were the two most common admitting diagnoses; 56 (37.6%) and 55 (36.8%) respectively. The most common indication was upper airway obstruction (129, 86.6%). Emergency tracheostomy was most commonly done (126, 84.6%) and majority of the tracheostomies were done under general anaesthesia (101, 67.8%). Trainee ENT surgeons performed the most tracheostomies (108, 72.5%). Surgical decanulation was done for 5 (3.4%) of the patients. The complication and mortality rates were 42.3% and 2.6% respectively. The most common period of complication was early postoperative period (46, 73.0%), and the most common complications were tube blockage and tube displacement (26, 41.3% and 11, 17.5%) respectively. The analyzed variables were not statistically significant determinants of tracheostomy-related complications among the patients. Conclusion: Tracheostomy-related complications are common, usually in the early postoperative period and usually involve blockage or displacement of the tube.","PeriodicalId":16477,"journal":{"name":"Journal of Medicine in the Tropics","volume":"453 1","pages":"93 - 99"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82934019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term treatment outcome of childhood epilepsy in Jos, Nigeria 尼日利亚乔斯儿童癫痫的短期治疗结果
Pub Date : 2020-07-01 DOI: 10.4103/jomt.jomt_6_20
E. Ejeliogu, A. Uhunmwangho-Courage, E. Yiltok, Mary Bok
Background: Childhood epilepsy causes tremendous burden for the child, the family, the society and the healthcare system. While the majority of patients with epilepsy respond well to one antiepileptic drug (AED), many respond poorly to antiepileptic therapy with two or more AEDs, or develop drug-resistant epilepsy (DRE). We evaluated the short-term treatment outcomes of childhood epilepsy at a tertiary hospital in Nigeria. Methods: We reviewed the clinical records of newly diagnosed children with epilepsy that were commenced on AEDs from January 2011 to December 2015 and completed follow-up for at least 2 years. We evaluated their treatment outcomes and studied the association between the treatment outcomes and patients’ characteristics. Results: Three hundred and twenty-six patients met the eligibility criteria. The remission rate was 64.1%, the relapse rate at 2 years was 5.3% while the prevalence of drug-resistant epilepsy was 19.9%. Children with focal seizures were 1.5 times more likely to achieve remission compared to those with generalized seizures (adjusted odds ratio = 1.52; P = 0.008). Similarly children with normal neurologic examination were about 6 times more likely to achieve remission compared to those with abnormal neurologic examination (adjusted odds ratio = 5.79; P <0.001). Conclusion: Most children with epilepsy will achieve good seizure control if they receive appropriate treatment. We need to create more public awareness on the etiology and treatment of epilepsy in order to reduce the myths and stigma associated with the disorder and improve the long term outcome of childhood epilepsy in our community.
背景:儿童癫痫给儿童、家庭、社会和卫生保健系统带来了巨大的负担。虽然大多数癫痫患者对一种抗癫痫药物(AED)反应良好,但许多患者对两种或两种以上抗癫痫药物治疗反应不佳,或发展为耐药癫痫(DRE)。我们评估了尼日利亚一家三级医院儿童癫痫的短期治疗结果。方法:回顾性分析2011年1月至2015年12月首次使用抗癫痫药物治疗的癫痫患儿的临床资料,随访时间不少于2年。我们评估了他们的治疗结果,并研究了治疗结果与患者特征之间的关系。结果:326例患者符合入选标准。缓解率为64.1%,2年复发率为5.3%,耐药癫痫患病率为19.9%。局灶性癫痫患儿获得缓解的可能性是全面性癫痫患儿的1.5倍(校正优势比= 1.52;p = 0.008)。同样,与神经系统检查异常的儿童相比,神经系统检查正常的儿童获得缓解的可能性约为6倍(校正优势比= 5.79;P < 0.001)。结论:多数癫痫患儿经适当治疗,癫痫发作控制效果良好。我们需要提高公众对癫痫病因和治疗的认识,以减少与该病有关的误解和污名,并改善我们社区儿童癫痫的长期结果。
{"title":"Short-term treatment outcome of childhood epilepsy in Jos, Nigeria","authors":"E. Ejeliogu, A. Uhunmwangho-Courage, E. Yiltok, Mary Bok","doi":"10.4103/jomt.jomt_6_20","DOIUrl":"https://doi.org/10.4103/jomt.jomt_6_20","url":null,"abstract":"Background: Childhood epilepsy causes tremendous burden for the child, the family, the society and the healthcare system. While the majority of patients with epilepsy respond well to one antiepileptic drug (AED), many respond poorly to antiepileptic therapy with two or more AEDs, or develop drug-resistant epilepsy (DRE). We evaluated the short-term treatment outcomes of childhood epilepsy at a tertiary hospital in Nigeria. Methods: We reviewed the clinical records of newly diagnosed children with epilepsy that were commenced on AEDs from January 2011 to December 2015 and completed follow-up for at least 2 years. We evaluated their treatment outcomes and studied the association between the treatment outcomes and patients’ characteristics. Results: Three hundred and twenty-six patients met the eligibility criteria. The remission rate was 64.1%, the relapse rate at 2 years was 5.3% while the prevalence of drug-resistant epilepsy was 19.9%. Children with focal seizures were 1.5 times more likely to achieve remission compared to those with generalized seizures (adjusted odds ratio = 1.52; P = 0.008). Similarly children with normal neurologic examination were about 6 times more likely to achieve remission compared to those with abnormal neurologic examination (adjusted odds ratio = 5.79; P <0.001). Conclusion: Most children with epilepsy will achieve good seizure control if they receive appropriate treatment. We need to create more public awareness on the etiology and treatment of epilepsy in order to reduce the myths and stigma associated with the disorder and improve the long term outcome of childhood epilepsy in our community.","PeriodicalId":16477,"journal":{"name":"Journal of Medicine in the Tropics","volume":"17 1","pages":"108 - 114"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91083502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Tropical diabetic hand syndrome: case report of successfully salvaged threatened dominant hand 热带糖尿病手综合征:受威胁的优势手抢救成功1例
Pub Date : 2020-07-01 DOI: 10.4103/jomt.jomt_20_20
K. Rajapaksha
Tropical diabetic hand syndrome (TDHS) is a less well-recognized complication of diabetes. It is characterized by cellulitis of hand and ends up with limb threatening significant tissue loss, sepsis and in occasion death. When the joint capsule and tendons are exposed in TDHS the digits and the limb and function of the hand are threatened. Loss of thumb of the dominant hand leads to devastating disability. The current case describes successfully managed case of TDHS with threatened thumb and function due to exposed first metacarpophalangeal joint and extensor tendons of the dominant hand.
热带糖尿病手综合征(TDHS)是一种鲜为人知的糖尿病并发症。它的特点是手部蜂窝织炎,最终危及肢体的显著组织损失,败血症,有时死亡。当关节囊和肌腱暴露在TDHS时,手指和肢体和手的功能受到威胁。失去惯用手的拇指会导致毁灭性的残疾。本病例描述了一例成功治疗的TDHS,由于第一掌指关节和优势手伸肌腱暴露,拇指和功能受到威胁。
{"title":"Tropical diabetic hand syndrome: case report of successfully salvaged threatened dominant hand","authors":"K. Rajapaksha","doi":"10.4103/jomt.jomt_20_20","DOIUrl":"https://doi.org/10.4103/jomt.jomt_20_20","url":null,"abstract":"Tropical diabetic hand syndrome (TDHS) is a less well-recognized complication of diabetes. It is characterized by cellulitis of hand and ends up with limb threatening significant tissue loss, sepsis and in occasion death. When the joint capsule and tendons are exposed in TDHS the digits and the limb and function of the hand are threatened. Loss of thumb of the dominant hand leads to devastating disability. The current case describes successfully managed case of TDHS with threatened thumb and function due to exposed first metacarpophalangeal joint and extensor tendons of the dominant hand.","PeriodicalId":16477,"journal":{"name":"Journal of Medicine in the Tropics","volume":"31 5","pages":"156 - 159"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91512990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Obstructive uropathy and intrinsic renal disease in patients with benign prostatic obstruction: analysis of burden and associations in a university teaching hospital in Nigeria 良性前列腺梗阻患者的梗阻性尿病和内在肾病:尼日利亚一所大学教学医院的负担及相关性分析
Pub Date : 2020-07-01 DOI: 10.4103/jomt.jomt_9_20
M. Tolani, Muhammed Ahmed, O. Nasir, A. Sudi
Background: Benign Prostatic Hyperplasia (BPH) is a disease of the elderly. Some of the patients with this pathology could develop renal impairment due to the direct effect of obstruction or as a result of intrinsic renal disease. This study aimed to determine the burden and associations of obstructive uropathy and intrinsic renal disease in patients with benign prostatic obstruction in a university teaching hospital in Nigeria. Methods: This was a retrospective study of patients with BPH in our center. Glomerular Filtration Rate (GFR) was calculated and the severity of renal disease computed. Patients were classified as normal or those with obstructive uropathy and intrinsic renal disease. Patients’ age, diabetes mellitus presence and treatment given were also documented. Results: Obstructive uropathy and intrinsic renal disease occurred in 14 (15.1%) and 12 (12.9%) of the patients respectively. Nephropathy in the setting of obstruction occurred in four (4.3%) of the patients while the GFR was at stage 2 in obstructive uropathy patients who did not have renal impairment. Eight (10.4%) of the patients without nephropathy had diabetes mellitus. There was a significant inverse relationship between the age of presentation and the GFR (P = 0.001, odds ratio = −1.129). Initial urinary drainage delayed definitive surgery in all patients with obstructive nephropathy. Conclusion: The burden of nephropathy in BPH patients is quite considerable. A proportion of those without renal impairment harbour diabetes mellitus which could rapidly tilt obstructive uropathy patients into renal failure.
背景:良性前列腺增生(BPH)是老年人的常见病。一些有这种病理的患者可能由于梗阻的直接影响或由于内在肾脏疾病而发展为肾脏损害。本研究旨在确定尼日利亚一所大学教学医院良性前列腺梗阻患者的负担和梗阻性尿病和内在肾病的相关性。方法:本研究是对本中心BPH患者的回顾性研究。计算肾小球滤过率(Glomerular Filtration Rate, GFR)和肾脏疾病严重程度。患者分为正常患者、梗阻性尿路病变患者和肾病患者。同时记录患者的年龄、是否患有糖尿病以及所接受的治疗。结果:梗阻性尿路病变14例(15.1%),肾病12例(12.9%)。梗阻情况下的肾病发生在4例(4.3%)患者中,而没有肾脏损害的梗阻性尿病患者的GFR处于2期。无肾病患者中有8例(10.4%)合并糖尿病。出现年龄与GFR呈显著负相关(P = 0.001,优势比= - 1.129)。所有梗阻性肾病患者的初始尿引流延迟了最终手术。结论:BPH患者的肾病负担相当大。无肾损害者中有一部分患有糖尿病,糖尿病可使梗阻性尿病患者迅速发展为肾功能衰竭。
{"title":"Obstructive uropathy and intrinsic renal disease in patients with benign prostatic obstruction: analysis of burden and associations in a university teaching hospital in Nigeria","authors":"M. Tolani, Muhammed Ahmed, O. Nasir, A. Sudi","doi":"10.4103/jomt.jomt_9_20","DOIUrl":"https://doi.org/10.4103/jomt.jomt_9_20","url":null,"abstract":"Background: Benign Prostatic Hyperplasia (BPH) is a disease of the elderly. Some of the patients with this pathology could develop renal impairment due to the direct effect of obstruction or as a result of intrinsic renal disease. This study aimed to determine the burden and associations of obstructive uropathy and intrinsic renal disease in patients with benign prostatic obstruction in a university teaching hospital in Nigeria. Methods: This was a retrospective study of patients with BPH in our center. Glomerular Filtration Rate (GFR) was calculated and the severity of renal disease computed. Patients were classified as normal or those with obstructive uropathy and intrinsic renal disease. Patients’ age, diabetes mellitus presence and treatment given were also documented. Results: Obstructive uropathy and intrinsic renal disease occurred in 14 (15.1%) and 12 (12.9%) of the patients respectively. Nephropathy in the setting of obstruction occurred in four (4.3%) of the patients while the GFR was at stage 2 in obstructive uropathy patients who did not have renal impairment. Eight (10.4%) of the patients without nephropathy had diabetes mellitus. There was a significant inverse relationship between the age of presentation and the GFR (P = 0.001, odds ratio = −1.129). Initial urinary drainage delayed definitive surgery in all patients with obstructive nephropathy. Conclusion: The burden of nephropathy in BPH patients is quite considerable. A proportion of those without renal impairment harbour diabetes mellitus which could rapidly tilt obstructive uropathy patients into renal failure.","PeriodicalId":16477,"journal":{"name":"Journal of Medicine in the Tropics","volume":"21 1","pages":"127 - 132"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72940089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preference for complementary and alternative medicine among patients on long-term treatment in Jos university teaching hospital, Nigeria. 尼日利亚乔斯大学教学医院长期治疗患者对补充和替代医学的偏好
Pub Date : 2020-07-01 Epub Date: 2020-09-11 DOI: 10.4103/jomt.jomt_29_20
Tolulope O Afolaranmi, Zuwaira I Hassan

Background: The use of complementary and alternative medicines(CAM) is on the increase globally particularly among those with chronic medical conditions. Imperatively, the treatment outcomes of management of chronic illness is hinged on adherence to prescribed conventional treatment with little or no attention paid to the intent to use or concomitant use of alternative medicines in most treatment settings. Hence, this study assessed the preference for CAM and its predictors as among patients on long-term treatment in Jos University Teaching Hospital.

Methods: This was a cross-sectional study conducted among 176 patients accessing treatment for chronic medical conditions in Jos University Teaching Hospital using quantitative method of data collection. Epi Info statistical software version 7 was used for data analysis with odds ratio and 95% confidence interval used as point and interval estimates respectively while a P-value of <0.05 was considered statistically significant.

Results: The median age of respondents was 50 (IQR 30-84) years with 83 (47.2%) being 51 years and above. Preference for CAM was reported by 26 (14.8%) with absence of side effects (AOR = 11.3; 95% CI= 5.8299-15.1185) being the sole predictor of preference for CAM.

Conclusion: This study has demonstrated some level of preference for CAM among patients on long term conventional treatment with perceived absence of side effects influencing this preference level.

背景:补充和替代药物(CAM)的使用在全球范围内呈增加趋势,特别是在慢性病患者中。必须指出的是,慢性疾病的治疗结果取决于对常规处方治疗的依从性,而在大多数治疗环境中很少或根本没有注意到使用替代药物的意图或同时使用替代药物。因此,本研究评估了乔斯大学教学医院长期治疗的患者对CAM的偏好及其预测因素。方法:采用数据收集定量方法,对Jos大学附属教学医院就诊的176例慢性疾病患者进行横断面研究。采用Epi Info统计软件第7版进行数据分析,分别采用优势比和95%置信区间作为点和区间估计,结果的p值为:受访者年龄中位数为50 (IQR 30-84)岁,51岁及以上的有83(47.2%)人。26例(14.8%)报告首选CAM,无副作用(AOR = 11.3;95% CI= 5.8299-15.1185)是CAM偏好的唯一预测因子。结论:本研究表明,长期接受常规治疗的患者对辅助替代治疗有一定程度的偏好,并且认为没有副作用会影响这种偏好水平。
{"title":"Preference for complementary and alternative medicine among patients on long-term treatment in Jos university teaching hospital, Nigeria.","authors":"Tolulope O Afolaranmi,&nbsp;Zuwaira I Hassan","doi":"10.4103/jomt.jomt_29_20","DOIUrl":"https://doi.org/10.4103/jomt.jomt_29_20","url":null,"abstract":"<p><strong>Background: </strong>The use of complementary and alternative medicines(CAM) is on the increase globally particularly among those with chronic medical conditions. Imperatively, the treatment outcomes of management of chronic illness is hinged on adherence to prescribed conventional treatment with little or no attention paid to the intent to use or concomitant use of alternative medicines in most treatment settings. Hence, this study assessed the preference for CAM and its predictors as among patients on long-term treatment in Jos University Teaching Hospital.</p><p><strong>Methods: </strong>This was a cross-sectional study conducted among 176 patients accessing treatment for chronic medical conditions in Jos University Teaching Hospital using quantitative method of data collection. Epi Info statistical software version 7 was used for data analysis with odds ratio and 95% confidence interval used as point and interval estimates respectively while a <i>P</i>-value of <0.05 was considered statistically significant.</p><p><strong>Results: </strong>The median age of respondents was 50 (IQR 30-84) years with 83 (47.2%) being 51 years and above. Preference for CAM was reported by 26 (14.8%) with absence of side effects (AOR = 11.3; 95% CI= 5.8299-15.1185) being the sole predictor of preference for CAM.</p><p><strong>Conclusion: </strong>This study has demonstrated some level of preference for CAM among patients on long term conventional treatment with perceived absence of side effects influencing this preference level.</p>","PeriodicalId":16477,"journal":{"name":"Journal of Medicine in the Tropics","volume":"22 2","pages":"147-152"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38893487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An insight into Ribavirin post-exposure prophylaxis for Lassa fever infection prevention amongst health-care workers in a specialist hospital in North-Central Nigeria 对尼日利亚中北部一家专科医院卫生保健工作者使用利巴韦林预防拉沙热感染的接触后预防的了解
Pub Date : 2020-07-01 DOI: 10.4103/jomt.jomt_8_20
C. Ononuju, Lucky Changkat, Chidozie Adiukwu, Ogedi Okwaraoha, Uzoma Chinaka, Y. Ashuku, Stella Chinaka, Elizabeth Ezeaku, Hassan Ikrama
Background: Oral ribavirin is used as standard post-exposure prophylaxis (PEP) in preventing the nosocomial spread of Lassa fever (LF) in outbreaks. This study sought to have an insight into the incidence and case fatality rate of Lassa fever infections, assess the biosocial data and outcome of the healthcare workers who received ribavirin PEP and determine the adverse effects associated with ribavirin PEP therapy at the Dalhatu Araf Specialist Hospital Lafia Nasarawa State Nigeria. Methods: This was a prospective study done between January 2017 to December 2018. Data on biosocial, details of exposure to the Lassa virus, the dosage of ribavirin therapy, adverse effects and outcomes were obtained. Results: The incidence of LF infection was 16% of all suspected cases, with a case fatality rate of 57.1%. General body weakness 30 (44.8%) and loss of appetite 25(37.2%) were the common adverse drug effects reported. The majority of the healthcare workers, 66 (98.5%) remained asymptomatic for secondary LF infection after completion of their oral ribavirin PEP, only, 1 (1.5%) became symptomatic for secondary LF infection, and expired on the sixth-day post-needlestick exposure. Conclusion: Lassa fever infection is common in Nasarawa State, and it is associated with a high case fatality rate. Healthcare workers on duty are at risk of being exposed when adherence to infection prevention and control is inadequate. Oral ribavirin PEP therapy was found to have a low adverse effect profile and efficacious in the prevention of symptomatic secondary LF infection.
背景:口服利巴韦林被用作标准的暴露后预防(PEP),以防止拉沙热(LF)疫情的院内传播。本研究旨在深入了解拉沙热感染的发病率和病死率,评估接受利巴韦林PEP治疗的卫生保健工作者的生物社会数据和结果,并确定尼日利亚拉菲亚纳萨拉瓦州达尔哈图阿拉夫专科医院利巴韦林PEP治疗相关的不良反应。方法:这是一项于2017年1月至2018年12月进行的前瞻性研究。获得了生物社会数据、接触拉沙病毒的详细情况、利巴韦林治疗剂量、不良反应和结局。结果:LF感染发生率为所有疑似病例的16%,病死率为57.1%。常见的不良反应为全身无力30例(44.8%)和食欲不振25例(37.2%)。大多数医护人员66人(98.5%)在完成口服利巴韦林PEP后仍无继发性LF感染症状,只有1人(1.5%)出现继发性LF感染症状,并在针刺暴露后第6天死亡。结论:拉沙热感染在纳萨拉瓦州很常见,并与高病死率有关。如果不充分遵守感染预防和控制,值班的卫生保健工作者就有被感染的风险。口服利巴韦林PEP治疗不良反应低,可有效预防有症状的继发性LF感染。
{"title":"An insight into Ribavirin post-exposure prophylaxis for Lassa fever infection prevention amongst health-care workers in a specialist hospital in North-Central Nigeria","authors":"C. Ononuju, Lucky Changkat, Chidozie Adiukwu, Ogedi Okwaraoha, Uzoma Chinaka, Y. Ashuku, Stella Chinaka, Elizabeth Ezeaku, Hassan Ikrama","doi":"10.4103/jomt.jomt_8_20","DOIUrl":"https://doi.org/10.4103/jomt.jomt_8_20","url":null,"abstract":"Background: Oral ribavirin is used as standard post-exposure prophylaxis (PEP) in preventing the nosocomial spread of Lassa fever (LF) in outbreaks. This study sought to have an insight into the incidence and case fatality rate of Lassa fever infections, assess the biosocial data and outcome of the healthcare workers who received ribavirin PEP and determine the adverse effects associated with ribavirin PEP therapy at the Dalhatu Araf Specialist Hospital Lafia Nasarawa State Nigeria. Methods: This was a prospective study done between January 2017 to December 2018. Data on biosocial, details of exposure to the Lassa virus, the dosage of ribavirin therapy, adverse effects and outcomes were obtained. Results: The incidence of LF infection was 16% of all suspected cases, with a case fatality rate of 57.1%. General body weakness 30 (44.8%) and loss of appetite 25(37.2%) were the common adverse drug effects reported. The majority of the healthcare workers, 66 (98.5%) remained asymptomatic for secondary LF infection after completion of their oral ribavirin PEP, only, 1 (1.5%) became symptomatic for secondary LF infection, and expired on the sixth-day post-needlestick exposure. Conclusion: Lassa fever infection is common in Nasarawa State, and it is associated with a high case fatality rate. Healthcare workers on duty are at risk of being exposed when adherence to infection prevention and control is inadequate. Oral ribavirin PEP therapy was found to have a low adverse effect profile and efficacious in the prevention of symptomatic secondary LF infection.","PeriodicalId":16477,"journal":{"name":"Journal of Medicine in the Tropics","volume":"10 1","pages":"122 - 126"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89521014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception and career choice of otorhinolaryngology among final year medical students: a two centre survey in a developing country 医学生对耳鼻喉科的认知和职业选择:一个发展中国家的两中心调查
Pub Date : 2020-07-01 DOI: 10.4103/jomt.jomt_17_20
A. Adekwu, F. Ibiam, G. Obasikene, M. Agbonifo, S. Unogwu, B. Ezeanolue
Background: Otorhinolaryngology (ORL) cares for pathologies involving the ear, nose, throat, however in the developing countries, it does not attract much patronage from young doctors thereby resulting in shortage of manpower in the subspecialty. This study was to assess the perception of otorhinolaryngology as a career and establish the factors involved in career choice among final year medical students in two universities in a developing country. Methods: A cross-sectional descriptive study undertaken using a self-administered questionnaire designed to assess the perception and determinants of career choice in ORL which was distributed to consenting final year medical students of the Benue State University (BSU), Makurdi and University of Nigeria (UNN), Enugu Campus. Results: A total of 122 questionnaires with complete data were analysed. Males constituted 65.6% while ages of participants were 21 to 37 years. BSU and UNN had 40 and 82 respondents respectively. Surgical specialties were the most preferred choice in 76 (62.3%) then Internal Medicine in 15 (12.3%). Otorhinolaryngology at 11 (14.5%) was the third preferred surgical specialty. Personal interest (78.4%), mentor influence (7.4%) and financial gain (7.4%) were the main determinants of specialty choice. Majority of the respondents 78 (63.9%) viewed Otorhinolaryngology as important and interesting. Modern teaching aids 24 (19.7%), increase in duration of posting 19 (15.6%), mentorship 15 (12.3%) were top suggestions that may attract interest in ORL. Conclusion: This study found that otorhinolaryngology was the third most preferred surgical subspecialty. Personal interest was the overriding reason for career choice among these medical students.
背景:耳鼻喉科(ORL)关注涉及耳、鼻、喉的病理,然而在发展中国家,它并没有吸引很多年轻医生的赞助,从而导致该亚专科的人力短缺。摘要本研究旨在探讨发展中国家两所大学医学生对耳鼻喉科职业的认知,并探讨影响其职业选择的因素。方法:采用自填问卷进行横断面描述性研究,旨在评估职业选择的感知和决定因素,该问卷分发给马库尔迪贝努埃州立大学(BSU)和尼日利亚大学(UNN)埃努古校区的最后一年级医科学生。结果:共分析问卷122份,数据完整。男性占65.6%,年龄在21 - 37岁之间。BSU和UNN分别有40名和82名受访者。76人(62.3%)首选外科专科,15人(12.3%)首选内科专科。耳鼻喉科占11(14.5%),是第三大首选外科专科。个人兴趣(78.4%)、导师影响(7.4%)和经济利益(7.4%)是专业选择的主要决定因素。大多数受访者中有78人(63.9%)认为耳鼻喉科重要且有趣。现代教具24个(19.7%)、增加张贴时间19个(15.6%)、导师15个(12.3%)是可能吸引学生对ORL感兴趣的建议。结论:本研究发现耳鼻喉科是第三大首选外科专科。在这些医学生中,个人兴趣是职业选择的首要原因。
{"title":"Perception and career choice of otorhinolaryngology among final year medical students: a two centre survey in a developing country","authors":"A. Adekwu, F. Ibiam, G. Obasikene, M. Agbonifo, S. Unogwu, B. Ezeanolue","doi":"10.4103/jomt.jomt_17_20","DOIUrl":"https://doi.org/10.4103/jomt.jomt_17_20","url":null,"abstract":"Background: Otorhinolaryngology (ORL) cares for pathologies involving the ear, nose, throat, however in the developing countries, it does not attract much patronage from young doctors thereby resulting in shortage of manpower in the subspecialty. This study was to assess the perception of otorhinolaryngology as a career and establish the factors involved in career choice among final year medical students in two universities in a developing country. Methods: A cross-sectional descriptive study undertaken using a self-administered questionnaire designed to assess the perception and determinants of career choice in ORL which was distributed to consenting final year medical students of the Benue State University (BSU), Makurdi and University of Nigeria (UNN), Enugu Campus. Results: A total of 122 questionnaires with complete data were analysed. Males constituted 65.6% while ages of participants were 21 to 37 years. BSU and UNN had 40 and 82 respondents respectively. Surgical specialties were the most preferred choice in 76 (62.3%) then Internal Medicine in 15 (12.3%). Otorhinolaryngology at 11 (14.5%) was the third preferred surgical specialty. Personal interest (78.4%), mentor influence (7.4%) and financial gain (7.4%) were the main determinants of specialty choice. Majority of the respondents 78 (63.9%) viewed Otorhinolaryngology as important and interesting. Modern teaching aids 24 (19.7%), increase in duration of posting 19 (15.6%), mentorship 15 (12.3%) were top suggestions that may attract interest in ORL. Conclusion: This study found that otorhinolaryngology was the third most preferred surgical subspecialty. Personal interest was the overriding reason for career choice among these medical students.","PeriodicalId":16477,"journal":{"name":"Journal of Medicine in the Tropics","volume":"130 1","pages":"141 - 146"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76409945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and pattern of sleep disorder among final year medical students in a teaching hospital in sub-Saharan Africa 撒哈拉以南非洲某教学医院医学生睡眠障碍的流行及模式
Pub Date : 2020-07-01 DOI: 10.4103/jomt.jomt_37_19
O. Osaigbovo, E. Ogbolu, B. Okeahialam
Background: Sleep is a very important physiologic process which is necessary to maintain a state of well-being. Apart from causing insomnia and hypersomnolence, sleep disorder has been shown to be associated with impairment of performance, vigilance, attention, concentration, and memory. Methods: This was a cross-sectional, questionnaire-based, observational study that was conducted from September to November 2017 on final year medical students of the University of Jos, Plateau State, North Central Nigeria. Results: One hundred and fifty-eight questionnaires were distributed with a total of 141 respondents. Their ages ranged from 23 to 46 years with a mean of 27.0 ±2.9 years. Forty-seven (33.3%) were females and 94 (66.7%) males giving a ratio of 1: 2. The female respondents had a mean age of 25.9 ±1.4 years compared to the male respondents 27.5 ±3.3 years. Sixty-four (48.2%) of the students had sleep disorder with narcolepsy as the commonest in over a quarter of respondents. Significant predictors of sleep disorders were male sex and obesity. Conclusion: Sleep disorder is common in final year medical students. There is a need to identify this disorder in these students in order to institute measures that will ameliorate its health consequences in these future healthcare leaders in sub-Saharan Africa.
背景:睡眠是一个非常重要的生理过程,是维持健康状态所必需的。除了引起失眠和嗜睡,睡眠障碍已被证明与表现、警惕性、注意力、注意力和记忆力的损害有关。方法:这是一项横断面、基于问卷的观察性研究,于2017年9月至11月在尼日利亚中北部高原州乔斯大学(University of Jos)的最后一年级医学生中进行。结果:共发放问卷158份,被调查者141人。年龄23 ~ 46岁,平均27.0±2.9岁。女性47例(33.3%),男性94例(66.7%),比例为1:2。女性平均年龄25.9±1.4岁,男性平均年龄27.5±3.3岁。64名学生(48.2%)有睡眠障碍,超过四分之一的受访者以嗜睡症最为常见。睡眠障碍的重要预测因素是男性和肥胖。结论:睡眠障碍在高年级医学生中较为常见。有必要确定这些学生的这种疾病,以便采取措施,改善撒哈拉以南非洲这些未来医疗保健领导者的健康后果。
{"title":"Prevalence and pattern of sleep disorder among final year medical students in a teaching hospital in sub-Saharan Africa","authors":"O. Osaigbovo, E. Ogbolu, B. Okeahialam","doi":"10.4103/jomt.jomt_37_19","DOIUrl":"https://doi.org/10.4103/jomt.jomt_37_19","url":null,"abstract":"Background: Sleep is a very important physiologic process which is necessary to maintain a state of well-being. Apart from causing insomnia and hypersomnolence, sleep disorder has been shown to be associated with impairment of performance, vigilance, attention, concentration, and memory. Methods: This was a cross-sectional, questionnaire-based, observational study that was conducted from September to November 2017 on final year medical students of the University of Jos, Plateau State, North Central Nigeria. Results: One hundred and fifty-eight questionnaires were distributed with a total of 141 respondents. Their ages ranged from 23 to 46 years with a mean of 27.0 ±2.9 years. Forty-seven (33.3%) were females and 94 (66.7%) males giving a ratio of 1: 2. The female respondents had a mean age of 25.9 ±1.4 years compared to the male respondents 27.5 ±3.3 years. Sixty-four (48.2%) of the students had sleep disorder with narcolepsy as the commonest in over a quarter of respondents. Significant predictors of sleep disorders were male sex and obesity. Conclusion: Sleep disorder is common in final year medical students. There is a need to identify this disorder in these students in order to institute measures that will ameliorate its health consequences in these future healthcare leaders in sub-Saharan Africa.","PeriodicalId":16477,"journal":{"name":"Journal of Medicine in the Tropics","volume":"614 1","pages":"86 - 92"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80429416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Clinical profile and viral load suppression among HIV positive adolescents attending a tertiary hospital in North Central Nigeria 在尼日利亚中北部三级医院就诊的艾滋病毒阳性青少年的临床概况和病毒载量抑制
Pub Date : 2020-07-01 DOI: 10.4103/jomt.jomt_13_20
E. Yiltok, Cordelia Agada, Ruth Zoakah, Aweng Malau, Dooh Tanyishi, E. Ejeliogu, A. Ebonyi
Background: The use of combination antiretroviral therapy (cART) helps in HIV viral load suppression and has improved survival of children into adolescence. The aim of the study was to look at the clinical profile and identify factors associated with HIV-viral load suppression among adolescents on long-term cART. Methods: Consenting adolescents aged 10–19 years attending the pediatric and adult antiretroviral therapy (ART) program of Jos University Teaching Hospital (JUTH) were enrolled into the study. A semi-structured interviewer administered questionnaire was used to collect the necessary information like the biodata, educational background, orphan and vulnerable children (OVC) status, and ART use. Self-reported adherence and viral load results were retrieved and data was analyzed using SPSS version 23. Results: A total of 143 were recruited into the study with 87(60.8%) females and 56(39.1%) males. Eighty-one (56.6%) had viral load suppression while 62 (43.4%) had unsuppressed viral load. Forty-three (55.1%) out of the 78 orphaned children had viral suppression and the single orphan type had a better viral load suppression compared to the double orphan type and this was statistically significant (P < 0.05). Adherence to medication, where adolescents lived, if felt like stopping medication or ever stopped medication were significantly associated with viral load suppression (P < 0.05). Conclusion: Virologic suppression was mainly related to adherence, being double orphan, and whom the child lives with. Therefore, additional interventions should be instituted to address adolescent-specific services to enhance virologic suppression among them.
背景:使用联合抗逆转录病毒治疗(cART)有助于抑制HIV病毒载量,并提高儿童进入青春期的存活率。该研究的目的是观察长期接受cART治疗的青少年的临床情况,并确定与hiv病毒载量抑制相关的因素。方法:自愿参加乔斯大学教学医院(Jos University Teaching Hospital, JUTH)儿童和成人抗逆转录病毒治疗(ART)项目的10-19岁青少年为研究对象。采用半结构化访谈问卷收集必要信息,如生物数据、教育背景、孤儿和弱势儿童(OVC)状况和抗逆转录病毒治疗使用情况。检索自我报告的依从性和病毒载量结果,并使用SPSS版本23对数据进行分析。结果:共纳入143例,其中女性87例(60.8%),男性56例(39.1%)。81例(56.6%)病毒载量被抑制,62例(43.4%)病毒载量未被抑制。78例孤儿中43例(55.1%)出现病毒抑制,单孤儿型病毒载量抑制优于双孤儿型,差异有统计学意义(P < 0.05)。在青少年生活的地方,是否坚持药物治疗,是否想停止药物治疗或曾经停止药物治疗与病毒载量抑制显著相关(P < 0.05)。结论:病毒学抑制主要与患儿依从性、双孤儿及生活环境有关。因此,应制定额外的干预措施,以解决青少年特定的服务,以加强他们之间的病毒学抑制。
{"title":"Clinical profile and viral load suppression among HIV positive adolescents attending a tertiary hospital in North Central Nigeria","authors":"E. Yiltok, Cordelia Agada, Ruth Zoakah, Aweng Malau, Dooh Tanyishi, E. Ejeliogu, A. Ebonyi","doi":"10.4103/jomt.jomt_13_20","DOIUrl":"https://doi.org/10.4103/jomt.jomt_13_20","url":null,"abstract":"Background: The use of combination antiretroviral therapy (cART) helps in HIV viral load suppression and has improved survival of children into adolescence. The aim of the study was to look at the clinical profile and identify factors associated with HIV-viral load suppression among adolescents on long-term cART. Methods: Consenting adolescents aged 10–19 years attending the pediatric and adult antiretroviral therapy (ART) program of Jos University Teaching Hospital (JUTH) were enrolled into the study. A semi-structured interviewer administered questionnaire was used to collect the necessary information like the biodata, educational background, orphan and vulnerable children (OVC) status, and ART use. Self-reported adherence and viral load results were retrieved and data was analyzed using SPSS version 23. Results: A total of 143 were recruited into the study with 87(60.8%) females and 56(39.1%) males. Eighty-one (56.6%) had viral load suppression while 62 (43.4%) had unsuppressed viral load. Forty-three (55.1%) out of the 78 orphaned children had viral suppression and the single orphan type had a better viral load suppression compared to the double orphan type and this was statistically significant (P < 0.05). Adherence to medication, where adolescents lived, if felt like stopping medication or ever stopped medication were significantly associated with viral load suppression (P < 0.05). Conclusion: Virologic suppression was mainly related to adherence, being double orphan, and whom the child lives with. Therefore, additional interventions should be instituted to address adolescent-specific services to enhance virologic suppression among them.","PeriodicalId":16477,"journal":{"name":"Journal of Medicine in the Tropics","volume":"12 1","pages":"133 - 140"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74318463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
期刊
Journal of Medicine in the Tropics
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1