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Journal of Neuro-Ophthalmology最新文献

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Zinc Optic Neuropathy. 锌视神经病变
IF 2 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-01 Epub Date: 2023-07-24 DOI: 10.1097/WNO.0000000000001939
Kathryn E McAnnis, Jennifer M Burnham, Dhaha A Alogaidi, Pamela A Davila, Noor A Laylani, Andrew G Lee
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引用次数: 0
Giant Cell Arteritis Presenting With Pulseless Disease. 巨细胞动脉炎表现为无脉搏疾病。
IF 2 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-01 Epub Date: 2023-06-14 DOI: 10.1097/WNO.0000000000001876
Baraa S Nawash, Joshua Ong, Peter Mortensen, Amrish Selvam, Andrew G Lee
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引用次数: 0
Identification of a de novo Case of COL3A1 -Related Ehlers-Danlos Syndrome in a Young Woman Presenting With Spontaneous Direct Carotid-Cavernous Fistula. 在一名出现自发性颈动脉-海绵状静脉瘘的年轻女性中发现与 COL3A1 相关的埃勒斯-丹洛斯综合征新病例
IF 2 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-01 Epub Date: 2023-07-07 DOI: 10.1097/WNO.0000000000001949
Hnin Hnin Oo, Saravana K Swaminathan, Wickly Lee, Julian Xinguang Han, Saumya S Jamuar, Breana Wen Min Cham, Su Ann Lim
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引用次数: 0
Early Identification and Treatment of Sjögren Syndrome With Bilateral Tonic Pupils: A Case Report. 早期识别和治疗伴有双侧强直性瞳孔的 Sjögren 综合征:病例报告。
IF 2 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-01 Epub Date: 2023-07-10 DOI: 10.1097/WNO.0000000000001937
Jihae Park, Hee Kyung Yang, You-Jung Ha, Jeong-Min Hwang
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引用次数: 0
When a Red Eye Is a Red Flag: A Nontraumatic Case of a Direct Carotid-Cavernous Fistula. 红眼就是红旗:颈动脉-颈静脉直接瘘的非创伤性病例
IF 2 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-01 Epub Date: 2023-04-19 DOI: 10.1097/WNO.0000000000001847
Margarida Ribeiro, Joana Oliveira, Jorge Meira, Ricardo Soares-Dos-Reis, Maria Luís Silva, Luís Albuquerque, Fernando Falcão-Reis, João Barbosa-Breda
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引用次数: 0
Subconjunctival Plasmacytoma Causing Diplopia. 结膜下浆细胞瘤导致复视
IF 2 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-01 Epub Date: 2023-05-11 DOI: 10.1097/WNO.0000000000001863
Gabriele Berman, Andre B Aung, Mung Y Lin, Nancy J Newman, Valérie Biousse
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引用次数: 0
Social Determinants of Health in Idiopathic Intracranial Hypertension. 特发性颅内高压症的健康社会决定因素。
IF 2 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-01 Epub Date: 2024-01-03 DOI: 10.1097/WNO.0000000000002073
Daniel Markowitz, Whitley W Aamodt, Ali G Hamedani

Background: Idiopathic intracranial hypertension (IIH) disproportionately affects women from socioeconomically disadvantaged communities, but specific social determinants of health have not been examined.

Methods: We used data from the National Institutes of Health's All of Us Research Program, an ongoing nationwide study of more than 300,000 diverse individuals in the United States. Height and weight were measured at baseline, and participants completed questionnaires about demographics, health care access, and quality of life. Women aged 18-50 years with IIH were identified through electronic health record data, excluding those with venous thrombosis, meningitis, hydrocephalus, or central nervous system neoplasms. We used logistic regression to compare questionnaire responses for IIH cases and controls, adjusting for age, race, ethnicity, annual income, and body mass index (BMI).

Results: We included 416 women with IIH and 107,111 women without IIH. The mean age was 38 years, and 49.3% identified as non-White. After adjusting for age, race/ethnicity, and BMI, women with IIH were more likely to be unemployed (odds ratio [OR] 1.40, 95% confidential interval [CI]: 1.14-1.71) and report delaying care because of difficulty affording copays (OR 1.47, 95% CI: 1.02-2.10) or specialist care (OR 1.52, 95% CI: 1.06-2.18). They also delayed care because of rural residence (OR 2.08, 95% CI: 1.25-3.47) and transportation limitations (OR 2.23, 95% CI: 1.55-3.20). Although women with IIH were more likely to be non-Hispanic Black (OR 1.66, 95% CI: 1.32-2.09), this association lost significance when controlling for BMI and income (OR 1.27, 95% CI: 0.96-1.68).

Conclusions: Women with IIH experience adverse social determinants of health beyond those associated with obesity alone.

背景:特发性颅内高压(IIH特发性颅内高压(IIH)对来自社会经济条件较差社区的女性的影响尤为严重,但尚未对健康的具体社会决定因素进行研究:我们使用了美国国立卫生研究院 "我们所有人研究计划"(All of Us Research Program)的数据。我们在基线测量了参与者的身高和体重,并填写了有关人口统计学、医疗保健和生活质量的调查问卷。我们通过电子健康记录数据确定了 18-50 岁患有 IIH 的女性,但排除了患有静脉血栓、脑膜炎、脑积水或中枢神经系统肿瘤的女性。我们使用逻辑回归法对 IIH 病例和对照组的问卷回答进行了比较,并对年龄、种族、民族、年收入和体重指数(BMI)进行了调整:我们纳入了 416 名患有 IIH 的女性和 107 111 名未患有 IIH 的女性。平均年龄为 38 岁,49.3% 为非白人。在对年龄、种族/民族和体重指数进行调整后,患有 IIH 的女性更有可能失业(几率比 [OR] 1.40,95% 置信区间 [CI]:1.14-1.71),并报告称因难以负担共付额(OR 1.47,95% CI:1.02-2.10)或专科护理(OR 1.52,95% CI:1.06-2.18)而延误护理。她们还因为居住在农村(OR 2.08,95% CI:1.25-3.47)和交通不便(OR 2.23,95% CI:1.55-3.20)而延误了治疗。虽然患有 IIH 的女性更有可能是非西班牙裔黑人(OR 1.66,95% CI:1.32-2.09),但在控制体重指数和收入(OR 1.27,95% CI:0.96-1.68)后,这种关联失去了意义:结论:患有 IIH 的女性所面临的不利健康社会决定因素超出了肥胖本身。
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引用次数: 0
Reexamining the Incidence of Nonarteritic Anterior Ischemic Optic Neuropathy: A Rochester Epidemiology Project Study. 重新审视非动脉炎性前部缺血性视神经病变的发病率:罗切斯特流行病学项目研究》。
IF 2 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-01 Epub Date: 2024-02-15 DOI: 10.1097/WNO.0000000000002102
Robert C Foster, M Tariq Bhatti, Olivia M Crum, Elizabeth R Lesser, David O Hodge, John J Chen

Background: This study aims to determine the population-based incidence and characterize the features of nonarteritic anterior ischemic optic neuropathy (NAION) using the Rochester Epidemiology Project (REP).

Methods: All patients diagnosed with an optic neuropathy from January 1, 1990, to December 31, 2016, were retrospectively reviewed to identify incident cases of NAION using the REP database, which is a record-linkage system of medical records for all patient-physician encounters among Olmsted County, Minnesota residents. The overall incidence of NAION was estimated using the age-specific and sex-specific population figures for Olmsted County census data for 1990 through 2016. Visual outcomes and risk factors were evaluated. The systemic risk factors were compared with age-matched controls.

Results: One hundred four patients were diagnosed with NAION during the 26-year study period. The overall age and sex adjusted incidence was 3.89 per 100,000 individuals (95% confidence interval [CI]: 3.14-4.65). The incidence was 7.73 (CI: 6.24-9.22) in patients aged 40 years or older and 10.19 (CI: 8.15-12.23) in patients aged 50 years or older. Median age at diagnosis was 65 years (range, 40-90 years), and 59 (56.7%) were male. The median logMAR visual acuity at presentation was 0.35 (Snellen equivalent of 20/40) with 14 patients (13.5%) having vision of counting fingers or worse. Among the 91 patients with final visual acuity outcome data available, the median visual acuity was 0.40 (Snellen equivalent of 20/50) with 12 patients (13.2%) having vision of counting fingers or worse. Twenty-four patients (26.4%) were noted to have final acuity at least 3 Snellen lines worse than at presentation, whereas 17 patients (18.7%) were noted to improve by at least 3 lines. The median mean deviation on automated visual field testing was -10.2 dB at presentation and -11.1 dB at follow-up. Twenty-two patients (21.2%) suffered NAION in the fellow eye; the median interval between involvement of the first and second eyes was 1.39 years. Systemic diseases present in the NAION cohort included hypertension (79.8%), diabetes mellitus (39.4%), obstructive sleep apnea (23.1%), and hyperlipidemia (74.0%), which were all statistically higher than age-matched controls.

Conclusions: NAION is a relatively common optic neuropathy in elderly patients with vascular risk factors. Our data indicate that the incidence of NAION has remained relatively stable in the population of Olmsted County over the past 4 decades.

背景:本研究旨在利用罗切斯特流行病学项目(REP)确定非动脉炎性前部缺血性视神经病变(NAION)的人群发病率和特征:REP数据库是明尼苏达州奥姆斯特德县居民所有患者-医生就诊病历的记录链接系统,对1990年1月1日至2016年12月31日期间诊断为视神经病变的所有患者进行了回顾性审查,以确定NAION的偶发病例。根据 1990 年至 2016 年奥姆斯特德县人口普查数据中特定年龄和性别的人口数字,估算出非内视性视网膜炎的总体发病率。对视觉结果和风险因素进行了评估。将系统性风险因素与年龄匹配的对照组进行了比较:在长达 26 年的研究期间,共有 144 名患者被确诊为非结节性视网膜病变。经年龄和性别调整后的总发病率为每 10 万人 3.89 例(95% 置信区间 [CI]:3.14-4.65)。40 岁或以上患者的发病率为 7.73(CI:6.24-9.22),50 岁或以上患者的发病率为 10.19(CI:8.15-12.23)。确诊时的中位年龄为 65 岁(40-90 岁不等),其中 59 人(56.7%)为男性。患者发病时的视力中位数为 0.35(相当于斯奈伦视力表 20/40),其中 14 名患者(13.5%)的视力为数指或更差。在有最终视力结果数据的 91 名患者中,视力中位数为 0.40(相当于斯奈伦标准的 20/50),其中 12 名患者(13.2%)的视力为数指或更差。有 24 名患者(26.4%)的最终视力比就诊时至少差 3 斯奈伦线,而有 17 名患者(18.7%)的视力至少提高了 3 斯奈伦线。自动视野测试的中位平均偏差在发病时为-10.2 dB,随访时为-11.1 dB。22名患者(21.2%)的同侧眼患有NAION;第一只眼和第二只眼受累的中位间隔时间为1.39年。NAION队列中存在的全身性疾病包括高血压(79.8%)、糖尿病(39.4%)、阻塞性睡眠呼吸暂停(23.1%)和高脂血症(74.0%),这些疾病在统计学上都高于年龄匹配的对照组:结论:在有血管风险因素的老年患者中,NAION 是一种相对常见的视神经病变。我们的数据表明,在过去 40 年中,NAION 在奥姆斯特德县人口中的发病率保持相对稳定。
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引用次数: 0
Insights Into Pediatric Neuro-Ophthalmology Research: Exploring Frontiers and Overcoming Hurdles. 洞察小儿神经眼科研究:探索前沿,克服困难。
IF 2 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-01 Epub Date: 2024-06-24 DOI: 10.1097/WNO.0000000000002199
Yin Allison Liu, Gillian R Paton
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引用次数: 0
Arteritic Anterior Ischemic Optic Neuropathy and Central Retinal Artery Occlusion in Polyarteritis Nodosa. 多发性结节性动脉炎的动脉前部缺血性视神经病变和视网膜中央动脉闭塞。
IF 2 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-09-01 Epub Date: 2023-06-19 DOI: 10.1097/WNO.0000000000001911
Micalla G Peng, Leonid M Zukin, William D Wallace, Maria E Sibug Saber, Daniel G Arkfeld, Jessica R Chang
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Journal of Neuro-Ophthalmology
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