Pub Date : 2020-04-01DOI: 10.22052/JNS.2020.02.015
Hind El Masaoudi, I. Benabdallah, B. Jaber, A. Laghzizil, M. Benaissa
In the present investigation, a systematic study on the dependence of chelating agents on the size control of silver phosphate Ag3PO4 powders is presented. The effect of two different capping-ligands (monoethanolamine (MEA) and oleylamine (OLA) as amino-additives) is studied using sol-gel route. Structural and morphological characterization techniques were used to quantify the particles size and molecular bonding. Results show that oleylamine as a chelating agent is more efficient in controlling the size of the as-synthesized nanoparticles, especially in low concentration of Ag+ precursor related to its long alkyl-chain preventing nuclei assemblage. This argument is confirmed by energy interaction calculation between Ag+ cations and oleylamine molecules using Molecular Dynamics Simulations. Finally, this investigation clearly demonstrates that the ratio between amino-additives (MEA and OLA) and Ag+ is the key-parameter that controls the crystalline growth of Ag3PO4 particles thus leading to nanometric size.
{"title":"Size Control of Ag3PO4 Nanoparticles Using Monoethanolamine and Oleylamine Chelating Agents","authors":"Hind El Masaoudi, I. Benabdallah, B. Jaber, A. Laghzizil, M. Benaissa","doi":"10.22052/JNS.2020.02.015","DOIUrl":"https://doi.org/10.22052/JNS.2020.02.015","url":null,"abstract":"In the present investigation, a systematic study on the dependence of chelating agents on the size control of silver phosphate Ag3PO4 powders is presented. The effect of two different capping-ligands (monoethanolamine (MEA) and oleylamine (OLA) as amino-additives) is studied using sol-gel route. Structural and morphological characterization techniques were used to quantify the particles size and molecular bonding. Results show that oleylamine as a chelating agent is more efficient in controlling the size of the as-synthesized nanoparticles, especially in low concentration of Ag+ precursor related to its long alkyl-chain preventing nuclei assemblage. This argument is confirmed by energy interaction calculation between Ag+ cations and oleylamine molecules using Molecular Dynamics Simulations. Finally, this investigation clearly demonstrates that the ratio between amino-additives (MEA and OLA) and Ag+ is the key-parameter that controls the crystalline growth of Ag3PO4 particles thus leading to nanometric size.","PeriodicalId":16523,"journal":{"name":"Journal of Nanostructures","volume":"10 1","pages":"362-374"},"PeriodicalIF":1.4,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43228901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.22052/JNS.2020.02.020
P. Pholnak, Jidapa Khongbun, Kullanan Suksom, M. Lertworapreecha, S. Suwanboon, C. Sirisathitkul
The antifungal properties of ZnO were implemented in the real handicraft and showed promising results for the value addition of local products by sun-screen and fungi protections. The inhibition of Aspergillus sp. growth on tube sedge basketry by zinc oxide (ZnO) was demonstrated. ZnO nanoparticles synthesized with chitosan capping agents were analyzed by X-ray diffractometry (XRD), Fourier transform infrared (FTIR) spectrophotometry and thermogravimetric analysis (TGA). The crystallite size consistent with electron microscope images and surface area of ZnO were dependent on the amounts of chitosan. ZnO exhibited a large ultraviolet (UV) absorbance in an entire 200-400 nm range when large crystallites agglomerated into bulky aggregates. In the case of small amounts of chitosan used, small crystallites tending to agglomerate in close contacts enhanced antifungal activity on pieces of tube sedge basketry. The fungi inhibition by this chitosan-modified ZnO was attributed to the stress response in fungal hyphae and generation of hydrogen peroxide.
{"title":"Antifungal Efficacy of Chitosan-Modified Zinc Oxide Nanoparticles on Tube Sedge Products","authors":"P. Pholnak, Jidapa Khongbun, Kullanan Suksom, M. Lertworapreecha, S. Suwanboon, C. Sirisathitkul","doi":"10.22052/JNS.2020.02.020","DOIUrl":"https://doi.org/10.22052/JNS.2020.02.020","url":null,"abstract":"The antifungal properties of ZnO were implemented in the real handicraft and showed promising results for the value addition of local products by sun-screen and fungi protections. The inhibition of Aspergillus sp. growth on tube sedge basketry by zinc oxide (ZnO) was demonstrated. ZnO nanoparticles synthesized with chitosan capping agents were analyzed by X-ray diffractometry (XRD), Fourier transform infrared (FTIR) spectrophotometry and thermogravimetric analysis (TGA). The crystallite size consistent with electron microscope images and surface area of ZnO were dependent on the amounts of chitosan. ZnO exhibited a large ultraviolet (UV) absorbance in an entire 200-400 nm range when large crystallites agglomerated into bulky aggregates. In the case of small amounts of chitosan used, small crystallites tending to agglomerate in close contacts enhanced antifungal activity on pieces of tube sedge basketry. The fungi inhibition by this chitosan-modified ZnO was attributed to the stress response in fungal hyphae and generation of hydrogen peroxide.","PeriodicalId":16523,"journal":{"name":"Journal of Nanostructures","volume":"10 1","pages":"424-433"},"PeriodicalIF":1.4,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42176713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.22052/JNS.2020.02.017
Behrouz Heidari, M. Fouladian, S. Fatemi
Microwave absorbing materials are usually designed to solve protection against electromagnetic interference in wireless communication systems and high frequency circuit mechanisms. In this research polystyrene (PS) nanocomposites containing various nano-fillers were successfully synthesized. The novelty of this work is comparing of three various nanostructures: non-metallic conductive graphene oxide, magnetic Fe3O4 and semi-conductor zinc oxide were used as additive. The effect of different fillers loading and homogenizer speed on the reflection loss (RL) amount and electromagnetic wave absorption was investigated. In order to investigate particle size and morphology of the nanostructures the scanning electron microscopy (SEM) was used. The frequency range of 5-8 GHz was employed in the investigation of electromagnetic wave absorption properties of nanocomposites using a vector network analyzer and eventually their absorption properties were analyzed and compared. The results indicate that graphene oxide has substantial effect on absorption in compare with the other nanocomposite samples. Increase of homogenizer speed led to a dispersion improvement of nanostructures and absorption. Therefore, the broadening of the microwave absorption band-width is attributed to the suitable dispersion of nanostructures in polymeric matrix.
{"title":"Improving Radar Absorbing Capability of Polystyrene Nanocomposites: Preparation and Investigation of Microwave Absorbing Properties","authors":"Behrouz Heidari, M. Fouladian, S. Fatemi","doi":"10.22052/JNS.2020.02.017","DOIUrl":"https://doi.org/10.22052/JNS.2020.02.017","url":null,"abstract":"Microwave absorbing materials are usually designed to solve protection against electromagnetic interference in wireless communication systems and high frequency circuit mechanisms. In this research polystyrene (PS) nanocomposites containing various nano-fillers were successfully synthesized. The novelty of this work is comparing of three various nanostructures: non-metallic conductive graphene oxide, magnetic Fe3O4 and semi-conductor zinc oxide were used as additive. The effect of different fillers loading and homogenizer speed on the reflection loss (RL) amount and electromagnetic wave absorption was investigated. In order to investigate particle size and morphology of the nanostructures the scanning electron microscopy (SEM) was used. The frequency range of 5-8 GHz was employed in the investigation of electromagnetic wave absorption properties of nanocomposites using a vector network analyzer and eventually their absorption properties were analyzed and compared. The results indicate that graphene oxide has substantial effect on absorption in compare with the other nanocomposite samples. Increase of homogenizer speed led to a dispersion improvement of nanostructures and absorption. Therefore, the broadening of the microwave absorption band-width is attributed to the suitable dispersion of nanostructures in polymeric matrix.","PeriodicalId":16523,"journal":{"name":"Journal of Nanostructures","volume":"10 1","pages":"392-403"},"PeriodicalIF":1.4,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45361653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.22052/JNS.2020.02.008
Azin Mazloom-Jalali, Z. Shariatinia
Three chitosan (CS), polyethylene glycol (PEG) and polylactic acid (PLA) nanocomposite systems containing SiO2 nanoparticles and water molecules were designed by molecular dynamics (MD) simulations to deliver pipobromane (PIP) anticancer drug in order to discover the most appropriate drug delivery system (DDS) in aqueous medium which was analogous to the human body. The density for the CS matrix was 1.25 g/cm3 but it was decreased to 1.16 g/cm3 in PLA and 1.02 g/cm3 in PEG. The potential energies of the CS, PLA and PEG DDSs were near 195000, 3700 and –4600 kcal/mol while their related non-bond energies were around 14000, –150 and –6150 kcal/mol, respectively, indicating the PEG composite had the most negative energies whereas the most positive values belonged to the CS system. The CS system revealed the greatest fractional free volume (FFV) of 77.232% but PLA offered the smallest FFV (65.804%). The radial distribution function (RDF) data displayed that the PIP molecules had strongest H-bond interactions with the CS chains which reflected the drug molecules would diffuse the slowest inside the CS nanocomposite. The diffusion coefficients for the PLA, PEG and CS systems were equal to 0.0183×10–4, 0.0163×10–4 and 0.0154×10–4 cm2/s, respectively approving the slowest drug diffusion was happened in the CS cell which certified the most controlled and sustained drug delivery.
{"title":"Molecular Dynamics Simulations on Polymeric Nanocomposite Membranes Designed to Deliver Pipobromane Anticancer Drug","authors":"Azin Mazloom-Jalali, Z. Shariatinia","doi":"10.22052/JNS.2020.02.008","DOIUrl":"https://doi.org/10.22052/JNS.2020.02.008","url":null,"abstract":"Three chitosan (CS), polyethylene glycol (PEG) and polylactic acid (PLA) nanocomposite systems containing SiO2 nanoparticles and water molecules were designed by molecular dynamics (MD) simulations to deliver pipobromane (PIP) anticancer drug in order to discover the most appropriate drug delivery system (DDS) in aqueous medium which was analogous to the human body. The density for the CS matrix was 1.25 g/cm3 but it was decreased to 1.16 g/cm3 in PLA and 1.02 g/cm3 in PEG. The potential energies of the CS, PLA and PEG DDSs were near 195000, 3700 and –4600 kcal/mol while their related non-bond energies were around 14000, –150 and –6150 kcal/mol, respectively, indicating the PEG composite had the most negative energies whereas the most positive values belonged to the CS system. The CS system revealed the greatest fractional free volume (FFV) of 77.232% but PLA offered the smallest FFV (65.804%). The radial distribution function (RDF) data displayed that the PIP molecules had strongest H-bond interactions with the CS chains which reflected the drug molecules would diffuse the slowest inside the CS nanocomposite. The diffusion coefficients for the PLA, PEG and CS systems were equal to 0.0183×10–4, 0.0163×10–4 and 0.0154×10–4 cm2/s, respectively approving the slowest drug diffusion was happened in the CS cell which certified the most controlled and sustained drug delivery.","PeriodicalId":16523,"journal":{"name":"Journal of Nanostructures","volume":"10 1","pages":"279-295"},"PeriodicalIF":1.4,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49104503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01DOI: 10.22052/JNS.2020.02.005
Somaye Khammarnia, A. Akbari, M. Ekrami-Kakhki, J. Saffari
In this work, NdFeO3 nanoparticles were synthesized through a simple co-precipitation method. The formation of NdFeO3 particles was verified by X-ray powder diffraction, infrared spectroscopy, vibrating sample magnetometer, and transmission electron microscopy analysis. Polyaniline and chitosan were employed as proper support for production of metal nanoparticles. Novel Pt-NFO/PA-CH nanocomposite was fabricated by immobilization of Pt nanoparticles on the PA-CH support in the presence of NdFeO3 nanoparticles. The prepared nanocomposite was characterized by transmission electron microscopy and X-ray powder diffraction analysis. The catalytic performance of the Pt-NFO/PA-CH nanocomposite was evaluated for electro-oxidation of methanol through CO stripping voltammetry, cyclic voltammetry, chronoamperometry, and electrochemical impedance spectroscopy. Durability of the Pt-NFO/PA-CH catalyst was investigated and the effects of several factors such as temperature, scan rate, and methanol concentration were studied for methanol oxidation. Enhanced catalytic performance of Pt-NFO/PA-CH nanocatalyst compared to Pt/PA-CH catalyst recommends its application for methanol electro-oxidation in direct methanol fuel cells.
{"title":"Enhanced Catalytic Activity of Pt-NdFeO3 Nanoparticles Supported on Polyaniline-Chitosan Composite Towards Methanol Electro-Oxidation Reaction","authors":"Somaye Khammarnia, A. Akbari, M. Ekrami-Kakhki, J. Saffari","doi":"10.22052/JNS.2020.02.005","DOIUrl":"https://doi.org/10.22052/JNS.2020.02.005","url":null,"abstract":"In this work, NdFeO3 nanoparticles were synthesized through a simple co-precipitation method. The formation of NdFeO3 particles was verified by X-ray powder diffraction, infrared spectroscopy, vibrating sample magnetometer, and transmission electron microscopy analysis. Polyaniline and chitosan were employed as proper support for production of metal nanoparticles. Novel Pt-NFO/PA-CH nanocomposite was fabricated by immobilization of Pt nanoparticles on the PA-CH support in the presence of NdFeO3 nanoparticles. The prepared nanocomposite was characterized by transmission electron microscopy and X-ray powder diffraction analysis. The catalytic performance of the Pt-NFO/PA-CH nanocomposite was evaluated for electro-oxidation of methanol through CO stripping voltammetry, cyclic voltammetry, chronoamperometry, and electrochemical impedance spectroscopy. Durability of the Pt-NFO/PA-CH catalyst was investigated and the effects of several factors such as temperature, scan rate, and methanol concentration were studied for methanol oxidation. Enhanced catalytic performance of Pt-NFO/PA-CH nanocatalyst compared to Pt/PA-CH catalyst recommends its application for methanol electro-oxidation in direct methanol fuel cells.","PeriodicalId":16523,"journal":{"name":"Journal of Nanostructures","volume":"10 1","pages":"239-257"},"PeriodicalIF":1.4,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43492954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-19DOI: 10.5772/intechopen.85698
A. A. Ayi, P. B. Ashishie, Emmanuel E. Khansi, J. Ogar, C. A. Anyama, B. Inah
Materials with structural elements, clusters and crystallites or molecules with size dimension in the range 1–100 nm and/or 4–20 Å have found potential and real applications as antimicrobial agents, catalysts, nano-filters in waste water treatments and scale forming ions removal etc. These nano/micro-structured materials possess large surface area which is one of the most important properties needed in different fields of applications. In this short review, the different protocols available for the synthesis ranging from green chemistry to chemical reduction methods, structural characterization, morphology and applications of nanostructured materials such as layered double hydroxides, silver and molybdenum oxides have been discussed.
{"title":"Nano/Micro-Structured Materials: Synthesis, Morphology and Applications","authors":"A. A. Ayi, P. B. Ashishie, Emmanuel E. Khansi, J. Ogar, C. A. Anyama, B. Inah","doi":"10.5772/intechopen.85698","DOIUrl":"https://doi.org/10.5772/intechopen.85698","url":null,"abstract":"Materials with structural elements, clusters and crystallites or molecules with size dimension in the range 1–100 nm and/or 4–20 Å have found potential and real applications as antimicrobial agents, catalysts, nano-filters in waste water treatments and scale forming ions removal etc. These nano/micro-structured materials possess large surface area which is one of the most important properties needed in different fields of applications. In this short review, the different protocols available for the synthesis ranging from green chemistry to chemical reduction methods, structural characterization, morphology and applications of nanostructured materials such as layered double hydroxides, silver and molybdenum oxides have been discussed.","PeriodicalId":16523,"journal":{"name":"Journal of Nanostructures","volume":"32 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2020-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91282831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.22052/JNS.2020.01.004
Amna Bashir, Fatima Bashir, Z. Akhter
Series of Copper Ruthenium (Cu-Ru) bimetallic catalysts supported on γ-Al2O3 with different metal loading are prepared and investigated for catalytic wet air oxidation of ammonia to nitrogen. The ammonia decomposition activity was studied at three different temperatures i.e. 150oC, 200oC, and 230 oC and it is found that catalytic activity increases with the increase in temperature along with the high selectivity towards nitrogen production. The results also revealed that the bimetallic Cu-Ru/ γ-Al2O3 are much more efficient especially stable than the corresponding monometallic Cu and Ru catalysts. Up to 99 % ammonia decomposed to N2 without any undesirable nitrites and nitrates at 230 oC by optimizing catalysts to ammonia ratio. So, it can be considered as a potential method to remove a large amount of ammonia from wastewater. Furthermore, the catalysts characterization results strongly suggested that there is a strong relationship between catalytic activity and Ru and Cu contents in bimetallic catalysts. The presences of both metals (Cu and Ru) affect the reactivity and coverage of oxygen species, as well as protecting each other from leaching. The combination of all effects including the strong interaction between metals, synergistic effect, proper oxygen coverage and resistance against leaching could be attributed to the enhancement of the catalytic activity of Cu-Ru/ γ-Al2O3 catalyst.
{"title":"Preparation and performance analysis of γ-Al2O3 supported Cu-Ru bimetallic catalysts for the selective Wet Air Oxidation of Aqueous Ammonia to Nitrogen.","authors":"Amna Bashir, Fatima Bashir, Z. Akhter","doi":"10.22052/JNS.2020.01.004","DOIUrl":"https://doi.org/10.22052/JNS.2020.01.004","url":null,"abstract":"Series of Copper Ruthenium (Cu-Ru) bimetallic catalysts supported on γ-Al2O3 with different metal loading are prepared and investigated for catalytic wet air oxidation of ammonia to nitrogen. The ammonia decomposition activity was studied at three different temperatures i.e. 150oC, 200oC, and 230 oC and it is found that catalytic activity increases with the increase in temperature along with the high selectivity towards nitrogen production. The results also revealed that the bimetallic Cu-Ru/ γ-Al2O3 are much more efficient especially stable than the corresponding monometallic Cu and Ru catalysts. Up to 99 % ammonia decomposed to N2 without any undesirable nitrites and nitrates at 230 oC by optimizing catalysts to ammonia ratio. So, it can be considered as a potential method to remove a large amount of ammonia from wastewater. Furthermore, the catalysts characterization results strongly suggested that there is a strong relationship between catalytic activity and Ru and Cu contents in bimetallic catalysts. The presences of both metals (Cu and Ru) affect the reactivity and coverage of oxygen species, as well as protecting each other from leaching. The combination of all effects including the strong interaction between metals, synergistic effect, proper oxygen coverage and resistance against leaching could be attributed to the enhancement of the catalytic activity of Cu-Ru/ γ-Al2O3 catalyst.","PeriodicalId":16523,"journal":{"name":"Journal of Nanostructures","volume":"10 1","pages":"28-38"},"PeriodicalIF":1.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68410854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.22052/JNS.2020.01.013
A. Baktash, O. Amiri, M. Saadat
Here, the effect of lightly Niobium doped TiO2 layer on the performance of perovskite solar cells has been studied by using solar cell capacitance simulator (SCAPS). N addition, the effects of Niobium concentration, buffer film thickness and operating temperature on the performance of the perovskite solar cell are investigated. For doping level of 3.0 mol% into the TiO2 layer, cell efficiency of 18.26% with Voc of 0.96 V, Jsc of 22.45 mA/ cm2 and FF of 84.25% has been achieved. Calculations show that thickness widening of Nb-doped TiO2 layer would decrease the efficiency and Voc of the cells. Increase in operating temperature from 300 k to 400 k would weaken the performance of the perovskite solar cell with both pure and Nb-doped TiO2 layers. However, the cell with Nb-doped TiO2 layer shows higher stability than the cell with pure TiO2 buffer at higher temperatures. The efficiency of the cell with pure and doped buffer layers decreased from 15.52% to 11.47% (with 26.09% reduction) and 18.26% to 14.07% (with 22.9% declination), respectively. Therefore, the cell with doped buffer layer shows better stability at higher operating temperatures
{"title":"High efficient Perovskite solar cells base on Niobium Doped TiO2 as a Buffer Layer","authors":"A. Baktash, O. Amiri, M. Saadat","doi":"10.22052/JNS.2020.01.013","DOIUrl":"https://doi.org/10.22052/JNS.2020.01.013","url":null,"abstract":"Here, the effect of lightly Niobium doped TiO2 layer on the performance of perovskite solar cells has been studied by using solar cell capacitance simulator (SCAPS). N addition, the effects of Niobium concentration, buffer film thickness and operating temperature on the performance of the perovskite solar cell are investigated. For doping level of 3.0 mol% into the TiO2 layer, cell efficiency of 18.26% with Voc of 0.96 V, Jsc of 22.45 mA/ cm2 and FF of 84.25% has been achieved. Calculations show that thickness widening of Nb-doped TiO2 layer would decrease the efficiency and Voc of the cells. Increase in operating temperature from 300 k to 400 k would weaken the performance of the perovskite solar cell with both pure and Nb-doped TiO2 layers. However, the cell with Nb-doped TiO2 layer shows higher stability than the cell with pure TiO2 buffer at higher temperatures. The efficiency of the cell with pure and doped buffer layers decreased from 15.52% to 11.47% (with 26.09% reduction) and 18.26% to 14.07% (with 22.9% declination), respectively. Therefore, the cell with doped buffer layer shows better stability at higher operating temperatures","PeriodicalId":16523,"journal":{"name":"Journal of Nanostructures","volume":"10 1","pages":"119-127"},"PeriodicalIF":1.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68411100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.22052/JNS.2020.01.015
A. Akbari, A. Akbarzadeh, M. Tehrani, R. A. Cohan, A. Mozaffari, M. Memarzadeh
Cancer is a fatal disease and relatively widespread in the world; Breast cancer is the most prevalent cancer among women. Hydroxyurea (HU) is a chemotherapy drug for the cure of cancer different types in patients, for example breast cancer, but has several defects, for to remove these problems in this study a nanoliposome (NL) suspension for Hydroxyurea (HU) delivery in breast cancer cell therapy was developed.HU was encapsulated into NLs. Size was measured by nanosizer. The release of the liposomal formulation was assessed during 36 h. FTIR analysis for liposomal Hydroxyurea and free Hydroxyurea was carried out. The uptake capacity of the formulation was determined by transfection of nanoliposomal hydroxyurea (NL-HU) in MDA-MB231 cells via flow cytometer and fluorescence microscopy studies, the cytotoxicity of NL-HU and free HU was evaluated in cells. Size of NL-HU was 174nm, HU encapsulation efficiencies in NLs was 81%. FTIR analysis showed the stability of HU in the liposome and no improper interaction between liposome and HU, release after 36h depicted sustained release behavior.NL-HU had suitable uptake in MDA-MB231 cells. Cytotoxicity of NL-HU on cells was considerable. We confirmed these nanoliposomes are potentially useful for delivery of Hydroxyurea in breast cancer cells treatment.
{"title":"Preparation and Evaluation of a Liposome Drug Delivery System in Cancer Treatment in vitro","authors":"A. Akbari, A. Akbarzadeh, M. Tehrani, R. A. Cohan, A. Mozaffari, M. Memarzadeh","doi":"10.22052/JNS.2020.01.015","DOIUrl":"https://doi.org/10.22052/JNS.2020.01.015","url":null,"abstract":"Cancer is a fatal disease and relatively widespread in the world; Breast cancer is the most prevalent cancer among women. Hydroxyurea (HU) is a chemotherapy drug for the cure of cancer different types in patients, for example breast cancer, but has several defects, for to remove these problems in this study a nanoliposome (NL) suspension for Hydroxyurea (HU) delivery in breast cancer cell therapy was developed.HU was encapsulated into NLs. Size was measured by nanosizer. The release of the liposomal formulation was assessed during 36 h. FTIR analysis for liposomal Hydroxyurea and free Hydroxyurea was carried out. The uptake capacity of the formulation was determined by transfection of nanoliposomal hydroxyurea (NL-HU) in MDA-MB231 cells via flow cytometer and fluorescence microscopy studies, the cytotoxicity of NL-HU and free HU was evaluated in cells. Size of NL-HU was 174nm, HU encapsulation efficiencies in NLs was 81%. FTIR analysis showed the stability of HU in the liposome and no improper interaction between liposome and HU, release after 36h depicted sustained release behavior.NL-HU had suitable uptake in MDA-MB231 cells. Cytotoxicity of NL-HU on cells was considerable. We confirmed these nanoliposomes are potentially useful for delivery of Hydroxyurea in breast cancer cells treatment.","PeriodicalId":16523,"journal":{"name":"Journal of Nanostructures","volume":"10 1","pages":"140-147"},"PeriodicalIF":1.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68411235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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