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Comparison of Monitored Anesthesia Care with Propofol Versus Dexmedetomidine for Awake Craniotomy: A Retrospective study 丙泊酚与右美托咪定用于清醒开颅术的监测麻醉护理的比较:回顾性研究
Q4 Medicine Pub Date : 2022-07-25 DOI: 10.1055/s-0042-1748195
Keta D. Thakkar, R. Mariappan, Krishna Prabhu, B. Yadav, Georgene Singh
Background Anesthetic agents used for awake craniotomy should be safe, short-acting, titratable, and provide an adequate level of sedation and analgesia, along with facilitating adequate neurological assessment during the functional testing. Our study aims to review the efficacy and safety profile, along with the potential for neurophysiological monitoring, of two commonly used anesthetic regimens, i.e., propofol and dexmedetomidine. Methods After the Ethics Committee approval, a retrospective analysis of 51 patients who underwent awake craniotomy for brain tumor excision over a period of 7 years was done. Those who received monitored anesthesia care (MAC) were divided into two groups, namely, Group P for that received propofol, and Group D that received dexmedetomidine and their hemodynamic profile, perioperative complications, neuromonitoring techniques, and postoperative course was noted from the records. Results A total of 31 patients were administered MAC with propofol and 20 with dexmedetomidine. The baseline demographic data, duration of surgery, intensive care unit (ICU), and hospital stay were comparable between the two. The hemodynamic profile as assessed by the heart rate and blood pressure was also comparable. The incidence of intraoperative seizures was found to be less in Group P, though. Episodes of transient desaturation were observed more in Group P (9.7%) than in Group D (5%), but none of the patients required conversion to general anesthesia. Direct cortical stimulation was satisfactorily elicited in 80% in Group P and 85% in Group D. Conclusions MAC with propofol and dexmedetomidine are acceptable techniques with comparable hemodynamic profile, intraoperative and postoperative complications, and potential for neurophysiological monitoring.
背景 用于清醒开颅手术的麻醉剂应是安全的、短效的、可滴定的,并提供足够的镇静和镇痛水平,同时便于在功能测试期间进行充分的神经评估。我们的研究旨在回顾两种常用麻醉方案(即丙泊酚和右美托咪定)的疗效和安全性,以及神经生理学监测的潜力。方法 在伦理委员会批准后,对51名在7年内接受清醒开颅脑肿瘤切除术的患者进行了回顾性分析。接受监测麻醉护理(MAC)的患者被分为两组,即P组接受丙泊酚治疗,D组接受右美托咪定治疗,并从记录中记录他们的血液动力学特征、围手术期并发症、神经监测技术和术后病程。后果 共有31名患者使用丙泊酚MAC,20名患者使用右美托咪定。基线人口统计数据、手术持续时间、重症监护室(ICU)和住院时间在两者之间具有可比性。通过心率和血压评估的血液动力学特征也具有可比性。然而,发现P组术中癫痫发作的发生率较低。P组(9.7%)比D组(5%)观察到更多的短暂性去饱和发作,但没有一名患者需要转为全身麻醉。直接皮层刺激在P组和D组中分别有80%和85%的患者满意。结论 丙泊酚和右美托咪定的MAC是可接受的技术,具有可比的血液动力学特征、术中和术后并发症以及神经生理监测的潜力。
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引用次数: 0
Association of ABO Blood Group Antigen and Neurological Tumors ABO血型抗原与神经系统肿瘤的关系
Q4 Medicine Pub Date : 2022-07-20 DOI: 10.1055/s-0042-1749656
G. Patidar, Y. Dhiman, A. Hazarika
Background Various risk factors for tumors such as smoking, alcohol consumption, diet, and radiation, etc., were already identified. ABO blood group antigens are also present on epithelia, endothelia, and neurons. Recent evidence suggested the role of ABO antigens in the pathogenesis of certain malignancies. Materials and Methods A retrospective observational study was conducted in a tertiary care neurosurgical center in North India from January 2016 to December 2018. The hospital information system was used to obtain patient information while the blood center information system was used to collect blood group information. Brain tumors were majorly divided into cavernoma, glioma, meningioma, neuroma, pituitary adenoma, schwannoma, and others. Results We found a total of 1,970 patients with brain tumors admitted during our study period. Most patients had glioma (33.55%), followed by pituitary adenoma (20.05%) and neuroma (2.23%). B blood group individuals had more prevalence of cavernoma, glioma, meningioma, pituitary adenoma, schwannoma, and others followed by O, A, and AB. Only association of O blood group with neuroma tumor was found statistically significant. Conclusions Our patient population had blood group distribution similar to our general population and no significant association was observed by blood group antigens and brain tumors. Although neuroma was significantly associated with blood group O but the prevalence of neuroma in our patient population is very low hence large sample study is required to draw a firm conclusion regarding this association.
背景 肿瘤的各种危险因素,如吸烟、饮酒、饮食和辐射等,已经被确定。ABO血型抗原也存在于上皮细胞、内皮细胞和神经元上。最近的证据表明ABO抗原在某些恶性肿瘤的发病机制中的作用。材料 方法2016年1月至2018年12月在北印度一家三级神经外科中心进行回顾性观察研究。医院信息系统用于获取患者信息,血液中心信息系统用于收集血型信息。脑肿瘤主要分为海绵状瘤、胶质瘤、脑膜瘤、神经瘤、垂体腺瘤、神经鞘瘤等。后果 我们发现,在我们的研究期间,共有1970名脑肿瘤患者入院。大多数患者患有神经胶质瘤(33.55%),其次是垂体腺瘤(20.05%)和神经瘤(2.23%)。B血型个体的海绵状瘤、神经胶质瘤、脑膜瘤、垂体腺瘤、神经鞘瘤和其他疾病的患病率更高,其次是O、A和AB。只有O血型与神经瘤肿瘤的相关性具有统计学意义。结论 我们的患者群体的血型分布与我们的普通人群相似,并且没有观察到血型抗原和脑肿瘤之间的显著关联。尽管神经瘤与O血型显著相关,但我们患者群体中神经瘤的患病率非常低,因此需要进行大样本研究才能得出关于这种关联的确切结论。
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引用次数: 0
Pediatric Microcuff Tube for Neurosurgical Procedures: A Boon or Bane? 用于神经外科手术的儿科微绒毛管:Boon还是Bane?
Q4 Medicine Pub Date : 2022-07-20 DOI: 10.1055/s-0042-1750092
Keta D. Thakkar, M. Sethuraman, A. Hrishi
Abstract Pediatric Microcuff endotracheal tubes have come into vogue in the last few years. It overcomes the problems faced with the uncuffed or conventional cuffed tubes used in the pediatric population. In addition, the more distal placement of the polyurethane cuffs in these tubes eliminates the risk of airway mucosal injury and hence postoperative stridor. This makes it an attractive option for neurosurgical patients where there is a high incidence of cranial nerve deficit, airway edema, and the requirement of prolonged postoperative ventilation. But due to this particular design, Murphy's eye is not incorporated in the tube, which can potentially hamper ventilation, especially when used for long duration surgery. With the help of our case report, we would like to warn the readers regarding this life-threatening complication that resulted in hypoxia in a 1-year-old child in the postoperative period.
摘要:小儿气管内微袖管在最近几年开始流行。它克服了在儿科人群中使用的无袖管或传统袖管所面临的问题。此外,在这些管中放置更远的聚氨酯袖带消除了气道粘膜损伤的风险,从而消除了术后喘鸣。这使得它成为脑神经缺损、气道水肿发生率高、术后需要长时间通气的神经外科患者的一个有吸引力的选择。但由于这种特殊的设计,墨菲的眼睛没有被纳入管中,这可能会阻碍通气,特别是在长时间的手术中。在我们的病例报告的帮助下,我们想提醒读者注意这一危及生命的并发症,导致1岁儿童术后缺氧。
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引用次数: 0
Incidence and Perioperative Risk Factors of Delayed Extubation following Pediatric Craniotomy for Intracranial Tumor: A 10-Year Retrospective Analysis in a Thailand Hospital 儿童颅内肿瘤开颅术后延迟拔管的发生率和围手术期危险因素:泰国一家医院10年回顾性分析
Q4 Medicine Pub Date : 2022-07-20 DOI: 10.1055/s-0042-1750421
Sunisa Sangtongjaraskul, Kornkamon Yuwapattanawong, Vorrachai Sae-Phua, Thichapat Jearranaiprepame, Paweena Paarporn
Abstract Background  The determination of extubation (early or delayed) after pediatric craniotomy for intracranial tumor should be carefully considered because each has its pros and cons. The aim of this study was to investigate the incidence of the delayed extubation in these patients. The secondary goal was to identify the perioperative factors influencing the determination of delayed extubation. Methods  This retrospective study was performed in pediatric patients with intracranial tumor who underwent craniotomy at a university hospital between April 2010 and March 2020. Preoperative and intraoperative variables were examined. The variables were compared between the delayed extubation and early extubation group. Results  Forty-two of 286 pediatric patients were in the delayed extubation group with an incidence of 14.69%. According to multivariate analyses, the risk factors that prompted delayed extubation were the intracranial tumor size ≥ 55 mm (adjusted odds ratio [AOR], 2.338; 95% confidence interval [CI], 1.032–5.295; p  = 0.042), estimated blood loss (EBL) ≥ 40% of calculated blood volume (AOR, 11.959; 95% CI, 3.457–41.377; p  < 0.001), blood transfusion (AOR, 3.093; 95% CI, 1.069–8.951; p  = 0.037), duration of surgery ≥ 300 minutes (AOR, 2.593; 95% CI, 1.099–6.120; p  = 0.030), and completion of the operation after working hours (AOR, 13.832; 95% CI, 2.997–63.835; p  = 0.001). Conclusions  The incidence of delayed extubation after pediatric craniotomy was 14.69%. The predictive factors were the size of tumor ≥ 55 mm, EBL ≥ 40% of calculated blood volume, blood transfusion, duration of surgery ≥ 300 minutes, and completion of surgery after routine working hours.
背景小儿颅内肿瘤开颅后是否提前或延迟拔管需要慎重考虑,各有利弊。本研究的目的是调查这些患者延迟拔管的发生率。次要目的是确定影响延迟拔管确定的围手术期因素。方法回顾性研究2010年4月至2020年3月在某大学医院行开颅手术的儿童颅内肿瘤患者。检查术前和术中变量。比较延迟拔管组和早期拔管组的各项指标。结果286例患儿中,延迟拔管组42例,发生率为14.69%。多因素分析提示延迟拔管的危险因素为颅内肿瘤大小≥55 mm(调整优势比[AOR], 2.338;95%置信区间[CI], 1.032-5.295;p = 0.042),估计失血量(EBL)≥计算血容量的40% (AOR, 11.959;95% ci, 3.457-41.377;p < 0.001)、输血(AOR, 3.093;95% ci, 1.069-8.951;p = 0.037),手术时间≥300分钟(AOR, 2.593;95% ci, 1.099-6.120;p = 0.030),下班后完成操作(AOR, 13.832;95% ci, 2.997-63.835;P = 0.001)。结论小儿开颅术后延迟拔管发生率为14.69%。预测因素为肿瘤大小≥55 mm, EBL≥计算血容量的40%,输血,手术时间≥300分钟,在常规工作时间后完成手术。
{"title":"Incidence and Perioperative Risk Factors of Delayed Extubation following Pediatric Craniotomy for Intracranial Tumor: A 10-Year Retrospective Analysis in a Thailand Hospital","authors":"Sunisa Sangtongjaraskul, Kornkamon Yuwapattanawong, Vorrachai Sae-Phua, Thichapat Jearranaiprepame, Paweena Paarporn","doi":"10.1055/s-0042-1750421","DOIUrl":"https://doi.org/10.1055/s-0042-1750421","url":null,"abstract":"Abstract Background  The determination of extubation (early or delayed) after pediatric craniotomy for intracranial tumor should be carefully considered because each has its pros and cons. The aim of this study was to investigate the incidence of the delayed extubation in these patients. The secondary goal was to identify the perioperative factors influencing the determination of delayed extubation. Methods  This retrospective study was performed in pediatric patients with intracranial tumor who underwent craniotomy at a university hospital between April 2010 and March 2020. Preoperative and intraoperative variables were examined. The variables were compared between the delayed extubation and early extubation group. Results  Forty-two of 286 pediatric patients were in the delayed extubation group with an incidence of 14.69%. According to multivariate analyses, the risk factors that prompted delayed extubation were the intracranial tumor size ≥ 55 mm (adjusted odds ratio [AOR], 2.338; 95% confidence interval [CI], 1.032–5.295; p  = 0.042), estimated blood loss (EBL) ≥ 40% of calculated blood volume (AOR, 11.959; 95% CI, 3.457–41.377; p  < 0.001), blood transfusion (AOR, 3.093; 95% CI, 1.069–8.951; p  = 0.037), duration of surgery ≥ 300 minutes (AOR, 2.593; 95% CI, 1.099–6.120; p  = 0.030), and completion of the operation after working hours (AOR, 13.832; 95% CI, 2.997–63.835; p  = 0.001). Conclusions  The incidence of delayed extubation after pediatric craniotomy was 14.69%. The predictive factors were the size of tumor ≥ 55 mm, EBL ≥ 40% of calculated blood volume, blood transfusion, duration of surgery ≥ 300 minutes, and completion of surgery after routine working hours.","PeriodicalId":16574,"journal":{"name":"Journal of Neuroanaesthesiology and Critical Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48613748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed Aspiration of Air Emboli from the Central Venous Catheter in a Case of Suspected Massive Venous Air Embolism: A Therapeutic Success 疑似大面积静脉空气栓塞的中心静脉导管延迟抽吸空气栓塞1例:治疗成功
Q4 Medicine Pub Date : 2022-07-20 DOI: 10.1055/s-0042-1748840
Ankur Khandelwal, S. Nayak, Anshil Bhatia, Amit K. Shrivastava, Vikas Bhardwaj
Abstract Venous air embolism (VAE), though, clinically benign in majority of cases, the significant ones can lead to life-threatening cardiopulmonary and neurological consequences. Though studies mention the success rate of only 6 to 16% in aspirating air from the central venous catheter (CVC) during VAE, the technique is very specific for diagnosing VAE and has high therapeutic significance. We report a case in which delayed aspiration of air emboli from the CVC in suspected massive VAE during decompressive craniectomy resulted in rapid resolution of hemodynamic instability. If not inserted previously, CVC may be considered in a hemodynamically unstable patient with suspected VAE.
静脉空气栓塞(VAE),虽然在临床上大多数情况下是良性的,但严重的可导致危及生命的心肺和神经系统后果。虽然有研究指出,在VAE过程中,从中心静脉导管(CVC)吸入空气的成功率仅为6%至16%,但该技术对VAE的诊断具有很强的特异性,具有很高的治疗意义。我们报告一例在开颅减压术中疑似大量VAE的CVC延迟吸入空气栓塞导致血流动力学不稳定的快速解决。如果之前没有插入CVC,在血流动力学不稳定的疑似VAE患者中可以考虑CVC。
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引用次数: 0
Effects of Magnesium Sulfate on Intraoperative Blood Loss and Anesthetic Requirement in Meningioma Patients Undergoing Craniotomy with Tumor Removal: A Prospective Randomized Study 硫酸镁对开颅肿瘤切除脑膜瘤患者术中失血和麻醉需求的影响:一项前瞻性随机研究
Q4 Medicine Pub Date : 2022-07-20 DOI: 10.1055/s-0042-1750692
Thanawut Jitsinthunun, M. Raksakietisak, Chanitda Pantubtim, Porntip Mahatnirunkul
Abstract Background  Meningioma brain tumor is associated with significant blood loss. Magnesium (Mg), a calcium blocker, can facilitate blood pressure control during surgery. This study aimed to evaluate effects of magnesium on blood loss, anesthetic requirement, and its neuroprotective effect in meningioma patients undergoing craniotomy. Methods  Eighty patients aged between 18 and 70, American Society of Anesthesiologists physical status I and II, diagnosed with meningioma and scheduled for craniotomy tumor removal were randomized into two groups. Group M (Mg) received intravenous magnesium sulfate 40 mg/kg over 30 minutes initiated at skin incision and followed by continuous infusion of 10 mg/kg/h until dura closure. Group N (NSS) received 0.9% NaCl as placebo. Anesthesiologists in charge, surgeons, and patients were all blinded. The assessed outcomes were perioperative blood loss, anesthetic requirement, and pre- and postoperative neurocognitive functions assessed by Montreal Cognitive Assessment (MoCA). Results  Thirty-eight patients in each group were analyzed. In group M, the intraoperative blood losses were 500 (70, 2300) mL, and 510 (100, 1600) mL in group N ( p  = 0.315). Patients who received blood within 24 hours were 39.5% in group M and 47.4% in group N ( p  = 0.644). No differences were observed in anesthetic requirement, intraoperative mean arterial pressure, hypotensive episodes, and vasopressor usages. There were no significant differences in postoperative MoCA score. Magnesium levels did not exceed acceptable levels. Conclusions  Magnesium administration in meningioma patients had no significant effects on blood loss, anesthetic requirement, and postoperative cognitive function.
背景脑膜瘤是一种与大量失血相关的脑肿瘤。镁(Mg)是一种钙阻滞剂,可以在手术期间帮助控制血压。本研究旨在评价镁对脑膜瘤开颅手术患者失血、麻醉需求及神经保护作用的影响。方法将80例年龄在18 ~ 70岁之间,经美国麻醉医师学会认证为I级和II级,诊断为脑膜瘤并计划开颅切除肿瘤的患者随机分为两组。M组(Mg)在皮肤切口处开始静脉注射硫酸镁40 Mg /kg,持续输注10 Mg /kg/h至硬脑膜闭合。N组(NSS)给予0.9% NaCl作为安慰剂。负责的麻醉师、外科医生和患者都被蒙蔽了双眼。评估的结果是围手术期出血量、麻醉需求以及蒙特利尔认知评估(MoCA)评估的术前和术后神经认知功能。结果两组各分析38例。M组术中出血量500(70、2300)mL, N组510(100、1600)mL (p = 0.315)。24小时内接受输血的患者M组为39.5%,N组为47.4% (p = 0.644)。在麻醉需求、术中平均动脉压、低血压发作和血管加压药的使用方面没有观察到差异。术后MoCA评分差异无统计学意义。镁含量没有超过可接受的水平。结论脑膜瘤患者给予镁对出血量、麻醉需要量及术后认知功能无明显影响。
{"title":"Effects of Magnesium Sulfate on Intraoperative Blood Loss and Anesthetic Requirement in Meningioma Patients Undergoing Craniotomy with Tumor Removal: A Prospective Randomized Study","authors":"Thanawut Jitsinthunun, M. Raksakietisak, Chanitda Pantubtim, Porntip Mahatnirunkul","doi":"10.1055/s-0042-1750692","DOIUrl":"https://doi.org/10.1055/s-0042-1750692","url":null,"abstract":"Abstract Background  Meningioma brain tumor is associated with significant blood loss. Magnesium (Mg), a calcium blocker, can facilitate blood pressure control during surgery. This study aimed to evaluate effects of magnesium on blood loss, anesthetic requirement, and its neuroprotective effect in meningioma patients undergoing craniotomy. Methods  Eighty patients aged between 18 and 70, American Society of Anesthesiologists physical status I and II, diagnosed with meningioma and scheduled for craniotomy tumor removal were randomized into two groups. Group M (Mg) received intravenous magnesium sulfate 40 mg/kg over 30 minutes initiated at skin incision and followed by continuous infusion of 10 mg/kg/h until dura closure. Group N (NSS) received 0.9% NaCl as placebo. Anesthesiologists in charge, surgeons, and patients were all blinded. The assessed outcomes were perioperative blood loss, anesthetic requirement, and pre- and postoperative neurocognitive functions assessed by Montreal Cognitive Assessment (MoCA). Results  Thirty-eight patients in each group were analyzed. In group M, the intraoperative blood losses were 500 (70, 2300) mL, and 510 (100, 1600) mL in group N ( p  = 0.315). Patients who received blood within 24 hours were 39.5% in group M and 47.4% in group N ( p  = 0.644). No differences were observed in anesthetic requirement, intraoperative mean arterial pressure, hypotensive episodes, and vasopressor usages. There were no significant differences in postoperative MoCA score. Magnesium levels did not exceed acceptable levels. Conclusions  Magnesium administration in meningioma patients had no significant effects on blood loss, anesthetic requirement, and postoperative cognitive function.","PeriodicalId":16574,"journal":{"name":"Journal of Neuroanaesthesiology and Critical Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44138489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective Analysis of 1998 Patients Diagnosed with Brain Death between 2011 and 2019 in Turkey 2011年至2019年土耳其1998例脑死亡患者的回顾性分析
Q4 Medicine Pub Date : 2022-07-20 DOI: 10.1055/s-0042-1750093
H. Sipahioğlu, Gulseren Elay, Nezahat Bingol, I. Bahar
Background Organ transplantation reduces mortality and morbidity in patients with end-stage organ failure. The number of living organ donations is not enough to meet the current organ transplantation need; therefore, there is an urgent need for organ donation from cadavers. We aimed to determine the organ donation rates and reveal the obstacles against donation. Methods This study is designed as a retrospective multicenter study consisting of eight university hospitals, three training and research hospitals, 26 state hospitals, and 74 private hospitals in nine provinces in Turkey. A total of 1,998 patients diagnosed with brain death between January 2011 to April 2019 were examined through the electronic medical records data system. Results Median patient age was 38 (IQR: 19–57), and 1,275 (63.8%) patients were male. The median time between the intensive care unit admission and brain death diagnosis was 56 (IQR:2–131) hours. The most commonly used confirmatory diagnostic test was computed tomography in 216 (30.8%) patients, and the most common cause of brain death was intraparenchymal hemorrhage with 617 (30.9%) patients. A total of 1,646 (82.4%) families refused to permit organ donation. The most common reasons for refusal were family disagreement (68%), social/relative pressure (24%), and religious beliefs (8%). Conclusions Many families refuse permission for organ donation; some of the provinces included in this study experienced years of exceptionally high refusal rates.
背景 器官移植可降低终末期器官衰竭患者的死亡率和发病率。活体器官捐献的数量不足以满足当前器官移植的需求;因此,迫切需要尸体器官捐献。我们旨在确定器官捐献率,并揭示阻碍器官捐献的障碍。方法 这项研究是一项回顾性多中心研究,由土耳其九个省的八所大学医院、三所培训和研究医院、26所州立医院和74所私立医院组成。在2011年1月至2019年4月期间,共有1998名被诊断为脑死亡的患者通过电子病历数据系统进行了检查。后果 患者的中位年龄为38岁(IQR:19-57),1275名(63.8%)患者为男性。重症监护室入院和脑死亡诊断之间的中位时间为56小时(IQR:2-131)。最常用的确认性诊断测试是216名(30.8%)患者的计算机断层扫描,最常见的脑死亡原因是617名(30.9%)患者的脑实质内出血。共有1646个(82.4%)家庭拒绝器官捐献。拒绝的最常见原因是家庭分歧(68%)、社会/相对压力(24%)和宗教信仰(8%)。结论 许多家庭拒绝器官捐献;这项研究中包括的一些省份经历了多年异常高的拒绝率。
{"title":"Retrospective Analysis of 1998 Patients Diagnosed with Brain Death between 2011 and 2019 in Turkey","authors":"H. Sipahioğlu, Gulseren Elay, Nezahat Bingol, I. Bahar","doi":"10.1055/s-0042-1750093","DOIUrl":"https://doi.org/10.1055/s-0042-1750093","url":null,"abstract":"Background Organ transplantation reduces mortality and morbidity in patients with end-stage organ failure. The number of living organ donations is not enough to meet the current organ transplantation need; therefore, there is an urgent need for organ donation from cadavers. We aimed to determine the organ donation rates and reveal the obstacles against donation. Methods This study is designed as a retrospective multicenter study consisting of eight university hospitals, three training and research hospitals, 26 state hospitals, and 74 private hospitals in nine provinces in Turkey. A total of 1,998 patients diagnosed with brain death between January 2011 to April 2019 were examined through the electronic medical records data system. Results Median patient age was 38 (IQR: 19–57), and 1,275 (63.8%) patients were male. The median time between the intensive care unit admission and brain death diagnosis was 56 (IQR:2–131) hours. The most commonly used confirmatory diagnostic test was computed tomography in 216 (30.8%) patients, and the most common cause of brain death was intraparenchymal hemorrhage with 617 (30.9%) patients. A total of 1,646 (82.4%) families refused to permit organ donation. The most common reasons for refusal were family disagreement (68%), social/relative pressure (24%), and religious beliefs (8%). Conclusions Many families refuse permission for organ donation; some of the provinces included in this study experienced years of exceptionally high refusal rates.","PeriodicalId":16574,"journal":{"name":"Journal of Neuroanaesthesiology and Critical Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45601604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Type-2 Neurofibromatosis Patient with Parasagittal Meningioma: A Challenging Airway 2型神经纤维瘤病伴矢状旁脑膜瘤患者的气道挑战
Q4 Medicine Pub Date : 2022-06-19 DOI: 10.1055/s-0042-1745724
Aparna Depuru, A. Barik, K. Jangra, N. Panda
Abstract The anesthetic management of a type-2 neurofibromatosis patient with a difficult airway is quite challenging. Such a situation tests the limits of the anesthesiologist's preparedness in maintaining the balance of the cerebral protection strategies and securing the airway. The anticipated challenges include managing the airway, controlling the raised intracranial pressure, and maintaining stable hemodynamics in anticipation of the expected blood loss. This article focuses on the preoperative airway evaluation and intraoperative preparedness in case of a patient with type-2 neurofibromatosis scheduled for craniotomy and excision of intracranial meningioma.
摘要气道困难的2型神经纤维瘤病患者的麻醉管理非常具有挑战性。这种情况考验了麻醉师在保持大脑保护策略平衡和保护气道方面的准备能力。预期的挑战包括管理气道,控制升高的颅内压,以及在预期失血的情况下保持稳定的血液动力学。本文重点介绍2型神经纤维瘤病患者开颅和颅内脑膜瘤切除术的术前气道评估和术中准备。
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引用次数: 0
Mobius Airo TruCT Scanner in the Operating Room: An Ergonomic Challenge to Neuroanesthesiologist 手术室中的Mobius Airo TruCT扫描仪:对神经麻醉师的人体工程学挑战
Q4 Medicine Pub Date : 2022-06-07 DOI: 10.1055/s-0042-1744401
S. Mallikarjuna, N. Ramakumar, B. Gupta, S. Chakraborty
Intraoperative imaging is a ubiquitous tool in neurosurgery, cranial and spinal procedures. Mobius Airo TruCT (Shirley, Massachusetts, United States) is the largest inner bore, mobile intraoperative computed tomography (CT) imaging system that seamlessly integrates into an operating room (OR) setup. 1 In transport mode, the ring is aligned with the base, and the scanner moves on the ramp to the desired location for scanning of the operative site. An intraoperative imaging system that gives high-quality images and a wide fi eld of vision in both two- and three dimensions is provided by this device. There are few reports on use of intraoperative CT in neurosurgery and spine surgeries. 2 – 4 There is a paucity of literature on the ergonomics of CT scanner location, anesthetic workstation placement, and patient alignment for CT-guided neuronavigation, or scanning from an anesthesiologist point of view; we found it worthwhile to share our limited experience.
术中成像在神经外科、颅脑和脊柱手术中是一种无处不在的工具。Mobius Airo TruCT (Shirley, Massachusetts, United States)是最大的内孔移动术中计算机断层扫描(CT)成像系统,可无缝集成到手术室(OR)设置中。1 .在运输模式下,环与底座对齐,扫描仪在斜坡上移动到所需位置,对操作部位进行扫描。该设备提供了一种术中成像系统,可提供高质量的图像和二维和三维的宽视野。术中CT在神经外科和脊柱外科的应用鲜有报道。2 - 4从麻醉师的角度来看,缺乏关于CT扫描仪位置、麻醉工作站位置和CT引导神经导航的患者对齐的人体工程学文献;我们觉得分享我们有限的经验是值得的。
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引用次数: 0
Management of a Patient with Bombay Blood Group and Chronic Liver Disease with Subdural Hematoma 孟买血型和慢性肝病合并硬膜下血肿患者的处理
Q4 Medicine Pub Date : 2022-06-07 DOI: 10.1055/s-0042-1744402
Siddharth Chavali, Subodh Raju, Suresh Kanasani, Abhirama C Gabbita
Abstract The Bombay blood group is an extremely rare entity within the conventional ABO blood grouping system. End-stage liver disease also presents with myriad disorders of coagulation due to impaired synthesis and dysfunction of clotting factors, which predisposes patients to spontaneous and life-threatening episodes of bleeding. We report a patient with Bombay blood group and end-stage liver disease who presented to our hospital with a spontaneous subdural hematoma. Although conventional parameters of coagulation in this patient were abnormal, we were able to safely defer product transfusion because his thromboelastography (TEG) report was within acceptable ranges. In this article, we discuss our strategy for optimization of extremely limited blood resources in this scenario and perioperative strategies for the management of coagulation anomalies in patients with liver dysfunction.
孟买血型是传统ABO血型系统中极为罕见的血型。终末期肝病还表现为由于凝血因子合成受损和功能障碍导致的无数凝血障碍,这使患者易发生自发性和危及生命的出血发作。我们报告一位孟买血型的终末期肝病患者,因自发性硬膜下血肿来我院就诊。虽然该患者的常规凝血参数异常,但我们能够安全地推迟产品输血,因为他的血栓弹性图(TEG)报告在可接受的范围内。在这篇文章中,我们讨论了在这种情况下对极其有限的血液资源进行优化的策略,以及肝功能障碍患者凝血异常的围手术期管理策略。
{"title":"Management of a Patient with Bombay Blood Group and Chronic Liver Disease with Subdural Hematoma","authors":"Siddharth Chavali, Subodh Raju, Suresh Kanasani, Abhirama C Gabbita","doi":"10.1055/s-0042-1744402","DOIUrl":"https://doi.org/10.1055/s-0042-1744402","url":null,"abstract":"Abstract The Bombay blood group is an extremely rare entity within the conventional ABO blood grouping system. End-stage liver disease also presents with myriad disorders of coagulation due to impaired synthesis and dysfunction of clotting factors, which predisposes patients to spontaneous and life-threatening episodes of bleeding. We report a patient with Bombay blood group and end-stage liver disease who presented to our hospital with a spontaneous subdural hematoma. Although conventional parameters of coagulation in this patient were abnormal, we were able to safely defer product transfusion because his thromboelastography (TEG) report was within acceptable ranges. In this article, we discuss our strategy for optimization of extremely limited blood resources in this scenario and perioperative strategies for the management of coagulation anomalies in patients with liver dysfunction.","PeriodicalId":16574,"journal":{"name":"Journal of Neuroanaesthesiology and Critical Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43318266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Neuroanaesthesiology and Critical Care
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