Miliary tuberculosis or disseminated tuberculosis is one of India's most typical forms of tuberculosis. It can have varied presentations, from classical pulmonary disease to affection of extra-pulmonary sites, the most common being the vertebral column. With a wide array of clinical manifestations, differentiating disseminated tuberculosis from common malignancies is no less than a herculean task for a clinician. Keeping a high index of clinical suspicion and detailed work up in the right direction can save the clinician and the patient from an exhaustive ordeal of futile investigations. Here, we present a rare case of miliary tuberculosis masquerading as a common malignancy of the elderly, re-emphasizing the need for a systematic approach to such confusing presentations.
{"title":"Miliary Tuberculosis Mimicking Multiple Myeloma: A Rare Case","authors":"J. Kaur, T. Raju, Y. Cheema, Jasmin Singh","doi":"10.5799/jmid.1130152","DOIUrl":"https://doi.org/10.5799/jmid.1130152","url":null,"abstract":"Miliary tuberculosis or disseminated tuberculosis is one of India's most typical forms of tuberculosis. It can have varied presentations, from classical pulmonary disease to affection of extra-pulmonary sites, the most common being the vertebral column. With a wide array of clinical manifestations, differentiating disseminated tuberculosis from common malignancies is no less than a herculean task for a clinician. Keeping a high index of clinical suspicion and detailed work up in the right direction can save the clinician and the patient from an exhaustive ordeal of futile investigations. Here, we present a rare case of miliary tuberculosis masquerading as a common malignancy of the elderly, re-emphasizing the need for a systematic approach to such confusing presentations.","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76993589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Aslan, S. Kocturk, M. Gül, M. Aslankurt, O. Altunoren
Objectives: This study aimed to evaluate whether conjunctival flora is different in patients with chronic renal disease (CR) among its subgroups and healthy subjects. Methods: A total of 105 adult CR patients; 35 hemodialysis (HD), 35 diabetic hemodialysis (DHD), 35 renal transplantation (RT), and 40 healthy subjects were enrolled. After ophthalmologic examination, a swab was taken from the lower fornix of the right eye using a cotton-tipped applicator and directly sub-cultured on 5% sheep’s blood agar, chocolate agar, and eosin methylene blue agar. Differences in both bacterial growth and flora diversity of the groups were compared. Results: The order of bacterial growth rates in the groups are RT 65%), DHD (57%), HD (56%), and control (48%). The RT group had a statistically significant difference from the control group (p
{"title":"Floral Differences of Conjunctiva in Patients with Renal Diseases","authors":"L. Aslan, S. Kocturk, M. Gül, M. Aslankurt, O. Altunoren","doi":"10.5799/jmid.1130130","DOIUrl":"https://doi.org/10.5799/jmid.1130130","url":null,"abstract":"Objectives: This study aimed to evaluate whether conjunctival flora is different in patients with chronic renal disease (CR) among its subgroups and healthy subjects. \u0000Methods: A total of 105 adult CR patients; 35 hemodialysis (HD), 35 diabetic hemodialysis (DHD), 35 renal transplantation (RT), and 40 healthy subjects were enrolled. After ophthalmologic examination, a swab was taken from the lower fornix of the right eye using a cotton-tipped applicator and directly sub-cultured on 5% sheep’s blood agar, chocolate agar, and eosin methylene blue agar. Differences in both bacterial growth and flora diversity of the groups were compared. \u0000Results: The order of bacterial growth rates in the groups are RT 65%), DHD (57%), HD (56%), and control (48%). The RT group had a statistically significant difference from the control group (p","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73014538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibiotic Susceptibility and Plasmid Profile of Multidrug resistant Uropathogenic Serratia marcescens","authors":"B. U. Nmesirionye, Chukwudi T. Ugwu, K. Nworie","doi":"10.5799/jmid.1085914","DOIUrl":"https://doi.org/10.5799/jmid.1085914","url":null,"abstract":"","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84308811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shreya Mahesh, Rajkumar Kalyan, P. Gupta, Sheetal Veram, V. Venkatesh, P. Tripathi
{"title":"MecA and ermA Gene Discrepancy from Their Phenotypic Profile in Staphylococcus aureus Isolates","authors":"Shreya Mahesh, Rajkumar Kalyan, P. Gupta, Sheetal Veram, V. Venkatesh, P. Tripathi","doi":"10.5799/jmid.1085907","DOIUrl":"https://doi.org/10.5799/jmid.1085907","url":null,"abstract":"","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"1221 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77679679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Mohamed, Sami E. A Algam, K. Enan, A. R. E. El Hussein, I. Elkhidir
{"title":"Molecular Detection of Leptospira in Pediatric Aseptic Meningitis","authors":"A. Mohamed, Sami E. A Algam, K. Enan, A. R. E. El Hussein, I. Elkhidir","doi":"10.5799/jmid.1086212","DOIUrl":"https://doi.org/10.5799/jmid.1086212","url":null,"abstract":"","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81827414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Suarez, R. Giner, Diana De Oliveira, Marcel Yibirin
Coronavirus disease 2019 (COVID-19) is an illness caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Malaria is a parasitic infection caused by the parasite genus Plasmodium. We present the case of a 69-year-old male indigenous patient from Amazonas, Venezuela, who complained of fever, cough, loss of taste and smel l, and diarrhea. A SARS-CoV-2 PCR test was positive, and treatment was started. However, over the next few days, his condition worsened. In addition to his previous symptoms, the patient reported profuse sweating accompanied by fever and myalgia. Therefore, a blood smear and ELISA were performed, which were positive for Plasmodium falciparum, for which treatment with antimalarial agents was also started. [ FROM AUTHOR] Copyright of Journal of Microbiology & Infectious Diseases is the property of Journal of Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
2019冠状病毒病(COVID-19)是由一种名为严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2)的新型冠状病毒引起的疾病。疟疾是一种由寄生虫属疟原虫引起的寄生虫感染。我们报告一名来自委内瑞拉亚马逊州的69岁土著男性患者，主诉发烧、咳嗽、味觉和嗅觉丧失以及腹泻。SARS-CoV-2 PCR检测呈阳性，并开始治疗。然而，在接下来的几天里，他的病情恶化了。除了先前的症状外，患者还报告大量出汗并伴有发烧和肌痛。因此，进行了血液涂片和ELISA检测，发现恶性疟原虫呈阳性，并开始使用抗疟药物进行治疗。《Journal of Microbiology & Infectious Diseases》的版权归《Journal of Microbiology & Infectious Diseases》所有，未经版权所有人的书面许可，其内容不得被复制或通过电子邮件发送到多个网站或发布到listserv。但是，用户可以打印、下载或通过电子邮件发送文章供个人使用。这可以删节。对副本的准确性不作任何保证。用户应参阅原始出版版本的材料的完整。(版权适用于所有人。)
{"title":"Malaria and COVID-19 in an Indigenous Patient, Overlapping of Two Febrile Illnesses","authors":"I. Suarez, R. Giner, Diana De Oliveira, Marcel Yibirin","doi":"10.5799/jmid.1086183","DOIUrl":"https://doi.org/10.5799/jmid.1086183","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) is an illness caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Malaria is a parasitic infection caused by the parasite genus Plasmodium. We present the case of a 69-year-old male indigenous patient from Amazonas, Venezuela, who complained of fever, cough, loss of taste and smel l, and diarrhea. A SARS-CoV-2 PCR test was positive, and treatment was started. However, over the next few days, his condition worsened. In addition to his previous symptoms, the patient reported profuse sweating accompanied by fever and myalgia. Therefore, a blood smear and ELISA were performed, which were positive for Plasmodium falciparum, for which treatment with antimalarial agents was also started. [ FROM AUTHOR] Copyright of Journal of Microbiology & Infectious Diseases is the property of Journal of Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81245016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Arthritogenic Arbovirus in Madagascar: State and Epidemic Risk","authors":"Rakotomalala Ni̇ari̇antsoa, Rakotomalala Hoby Nomena, Rakotoson Juli̇en, R. Antsa, Ranaivoarison Veroni̇que, Ralandison Stéphane","doi":"10.5799/jmid.1085937","DOIUrl":"https://doi.org/10.5799/jmid.1085937","url":null,"abstract":"","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83401971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohd Fardeen Husain Shahanshah, Saloni Jain, Bhawna Sharma, Ananya Grewall, S. Swami
The emergence of numerous variants of SARS-CoV-2 has caused massive setbacks and prolonged the COVID-19 pandemic. Some of the variants are still under investigation, while some have become a reason of grave concern. One such variant is B.1.617.2, known as the Delta variant, which was first detected in India. A comprehensive analysis and comparison of this particular variant have been done to the original Wuhan strain, and the possible reasons behind rapid mutation have also been discussed. A comprehensive literature search was done to summarize the information on the variants of SARS-CoV-2 and the reasons behind their mutation, with a significant focus on the B.1.617.2 variant. Data were collected from various online sources such as PubMed, Google Scholar, MEDLINE, Worldometer, WHO, CDC, and GISAID. In addition, 3D structures of spike proteins were obtained from Protein Data Bank (PDB). The data shows that the spike protein of the B.1.617.2 strain is highly mutated and has accumulated eight amino acid changes. Besides spike protein, changes in non-structural proteins (nsP2, nsP3, nsP4, nsP12, and nsP15), other structural proteins (nucleocapsid and membrane protein), and accessory proteins (ns3, ns7a) have been observed as well. Furthermore, in almost all the variants of SARS-CoV-2, D614G mutation occurs, suggesting its role in increased infectivity and transmission. New variants are continuously emerging on which we have no control. Spike mutations are more favored and essential in the evolution of new variants because it increases the transmissibility and infectivity of the virus. Therefore, to maximally protect public health, knowledge of different variants is essential. [ FROM AUTHOR] Copyright of Journal of Microbiology & Infectious Diseases is the property of Journal of Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
许多SARS-CoV-2变种的出现造成了巨大挫折，并延长了COVID-19大流行。其中一些变体仍在调查中，而一些变体已引起严重关注。其中一种变异是B.1.617.2，被称为Delta变异，最早是在印度发现的。对该变异与原武汉株进行了综合分析和比较，并对其快速突变的可能原因进行了探讨。我们进行了全面的文献检索，总结了SARS-CoV-2变异的信息及其突变背后的原因，重点关注了B.1.617.2变异。数据收集自各种在线资源，如PubMed、Google Scholar、MEDLINE、Worldometer、WHO、CDC和GISAID。此外，从蛋白质数据库(Protein Data Bank, PDB)中获得了刺突蛋白的三维结构。结果表明，菌株B.1.617.2的刺突蛋白发生了高度突变，积累了8个氨基酸变化。除刺突蛋白外，非结构蛋白(nsP2、nsP3、nsP4、nsP12和nsP15)、其他结构蛋白(核衣壳和膜蛋白)和辅助蛋白(ns3、ns7a)也发生了变化。此外，在几乎所有SARS-CoV-2变体中，都会发生D614G突变，这表明其在增加传染性和传播中的作用。新的变种不断出现，我们无法控制。刺突突变在新变异的进化中更受青睐和重要，因为它增加了病毒的传播性和传染性。因此，为了最大限度地保护公众健康，了解不同的变异是必不可少的。《Journal of Microbiology & Infectious Diseases》的版权归《Journal of Microbiology & Infectious Diseases》所有，未经版权所有人的书面许可，其内容不得被复制或通过电子邮件发送到多个网站或发布到listserv。但是，用户可以打印、下载或通过电子邮件发送文章供个人使用。这可以删节。对副本的准确性不作任何保证。用户应参阅原始出版版本的材料的完整。(版权适用于所有人。)
{"title":"Comparative Analysis of B.1.617.2 (Delta) Variant of SARS-CoV-2","authors":"Mohd Fardeen Husain Shahanshah, Saloni Jain, Bhawna Sharma, Ananya Grewall, S. Swami","doi":"10.5799/jmid.1086226","DOIUrl":"https://doi.org/10.5799/jmid.1086226","url":null,"abstract":"The emergence of numerous variants of SARS-CoV-2 has caused massive setbacks and prolonged the COVID-19 pandemic. Some of the variants are still under investigation, while some have become a reason of grave concern. One such variant is B.1.617.2, known as the Delta variant, which was first detected in India. A comprehensive analysis and comparison of this particular variant have been done to the original Wuhan strain, and the possible reasons behind rapid mutation have also been discussed. A comprehensive literature search was done to summarize the information on the variants of SARS-CoV-2 and the reasons behind their mutation, with a significant focus on the B.1.617.2 variant. Data were collected from various online sources such as PubMed, Google Scholar, MEDLINE, Worldometer, WHO, CDC, and GISAID. In addition, 3D structures of spike proteins were obtained from Protein Data Bank (PDB). The data shows that the spike protein of the B.1.617.2 strain is highly mutated and has accumulated eight amino acid changes. Besides spike protein, changes in non-structural proteins (nsP2, nsP3, nsP4, nsP12, and nsP15), other structural proteins (nucleocapsid and membrane protein), and accessory proteins (ns3, ns7a) have been observed as well. Furthermore, in almost all the variants of SARS-CoV-2, D614G mutation occurs, suggesting its role in increased infectivity and transmission. New variants are continuously emerging on which we have no control. Spike mutations are more favored and essential in the evolution of new variants because it increases the transmissibility and infectivity of the virus. Therefore, to maximally protect public health, knowledge of different variants is essential. [ FROM AUTHOR] Copyright of Journal of Microbiology & Infectious Diseases is the property of Journal of Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82762327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Singh, Nikita Sherwani, Jyoti Jaiswal, Tripti Nagaria, A. Neral, O. Khandwal
Objectives: The coronavirus disease 2019 (COVID-19) outbreak is evolving rapidly worldwide. However, little is known about the association between pregnant women with COVID-19 and its transmission to neonates. This investigation aimed to see if COVID-19 infection could be transmitted vertically into the uterus. Methods: We conducted a prospective observational study. 48 COVID-19 infected mothers were enrolled during their third trimester. A qRT-PCR assay of the nasal and oropharyngeal swab samples was performed to confirm positive for COVID-19 infection as per WHO protocol. In addition, characteristics of pregnant women with confirmed SARS -CoV-2 infection and newborns were documented. Results: Forty-eight expectant mothers, 10 (20.8%) were found symptomatic, and 38 (79.2%) were asymptomatic, with COVID-19 infection were delivered (33 cesarean section & 15 vaginal deliveries). One female child (4.1%) out of 48 newborns was initially diagnosed with COVID-19 infection based on a nucleic acid qRT-PCR. The female child showed no or negligible signs and recovered completely, whereas 47 neonates (95.9%) confirmed negative. None of the mothers or neonates died from COVID-19 related pulmonary problems. Conclusion: There is insufficient evidence on vertical virologic transmission of COVID-19 infection during the third trimester of pregnancy. Additionally, research and surveillance involving adequate testing of samples of placental tissue, breast milk, vaginal swab, amniotic fluid, and cord blood will be needed to establish the possibility of vertical transmission of infection. [ FROM AUTHOR] Copyright of Journal of Microbiology & Infectious Diseases is the property of Journal of Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
目的:2019冠状病毒病(COVID-19)疫情在全球范围内迅速演变。然而，人们对孕妇感染COVID-19与其传播给新生儿之间的关系知之甚少。这项调查旨在了解COVID-19感染是否可以垂直传播到子宫。方法:我们进行了前瞻性观察研究。48名感染COVID-19的母亲在妊娠晚期被招募。根据世卫组织方案，对鼻和口咽拭子样本进行了qRT-PCR检测，以确认COVID-19感染呈阳性。此外，还记录了确诊为SARS -CoV-2感染的孕妇和新生儿的特征。结果:48例新冠肺炎感染孕妇中有症状者10例(20.8%)，无症状者38例(79.2%)，其中剖宫产33例，顺产15例。48名新生儿中有1名女婴(4.1%)经核酸qRT-PCR初步诊断为COVID-19感染。女婴无症状或可忽略，完全康复，而47例新生儿(95.9%)确诊为阴性。没有母亲或新生儿死于与COVID-19相关的肺部问题。结论:妊娠晚期COVID-19感染的垂直病毒学传播证据不足。此外，需要开展研究和监测，对胎盘组织、母乳、阴道拭子、羊水和脐带血样本进行充分检测，以确定感染垂直传播的可能性。《Journal of Microbiology & Infectious Diseases》的版权归《Journal of Microbiology & Infectious Diseases》所有，未经版权所有人的书面许可，其内容不得被复制或通过电子邮件发送到多个网站或发布到listserv。但是，用户可以打印、下载或通过电子邮件发送文章供个人使用。这可以删节。对副本的准确性不作任何保证。用户应参阅原始出版版本的材料的完整。(版权适用于所有人。)
{"title":"Vertical Virus Transmission from SARS-CoV-2-positive Mothers to Neonates: A Tertiary Care Hospital Experience","authors":"N. Singh, Nikita Sherwani, Jyoti Jaiswal, Tripti Nagaria, A. Neral, O. Khandwal","doi":"10.5799/jmid.1085903","DOIUrl":"https://doi.org/10.5799/jmid.1085903","url":null,"abstract":"Objectives: The coronavirus disease 2019 (COVID-19) outbreak is evolving rapidly worldwide. However, little is known about the association between pregnant women with COVID-19 and its transmission to neonates. This investigation aimed to see if COVID-19 infection could be transmitted vertically into the uterus. Methods: We conducted a prospective observational study. 48 COVID-19 infected mothers were enrolled during their third trimester. A qRT-PCR assay of the nasal and oropharyngeal swab samples was performed to confirm positive for COVID-19 infection as per WHO protocol. In addition, characteristics of pregnant women with confirmed SARS -CoV-2 infection and newborns were documented. Results: Forty-eight expectant mothers, 10 (20.8%) were found symptomatic, and 38 (79.2%) were asymptomatic, with COVID-19 infection were delivered (33 cesarean section & 15 vaginal deliveries). One female child (4.1%) out of 48 newborns was initially diagnosed with COVID-19 infection based on a nucleic acid qRT-PCR. The female child showed no or negligible signs and recovered completely, whereas 47 neonates (95.9%) confirmed negative. None of the mothers or neonates died from COVID-19 related pulmonary problems. Conclusion: There is insufficient evidence on vertical virologic transmission of COVID-19 infection during the third trimester of pregnancy. Additionally, research and surveillance involving adequate testing of samples of placental tissue, breast milk, vaginal swab, amniotic fluid, and cord blood will be needed to establish the possibility of vertical transmission of infection. [ FROM AUTHOR] Copyright of Journal of Microbiology & Infectious Diseases is the property of Journal of Microbiology & Infectious Diseases and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83868006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muna Malik, F. K. Akhtar, K. Bhinder, Z. Sarfraz, A. Ameena, Ali Hashim Zubai̇r, A. Sarfraz, Zubair Saleem
{"title":"Diagnostics and Clinical Care of Nocardia Keratitis","authors":"Muna Malik, F. K. Akhtar, K. Bhinder, Z. Sarfraz, A. Ameena, Ali Hashim Zubai̇r, A. Sarfraz, Zubair Saleem","doi":"10.5799/jmid.1086199","DOIUrl":"https://doi.org/10.5799/jmid.1086199","url":null,"abstract":"","PeriodicalId":16603,"journal":{"name":"Journal of Microbiology and Infectious Diseases","volume":"111 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83454559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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