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Effect of a Thermosensitive Hydroxybutyl Chitosan Hydrogel on Postoperative Sequalae and Quality of Life After Impacted Mandibular Third Molar Extraction 热敏羟丁基壳聚糖水凝胶对影响下颌第三磨牙拔除术后疼痛和生活质量的影响
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.joms.2024.06.165

Background

Third molar (M3) extraction is a common surgery in oral and maxillofacial surgery, and composite wound dressings such as hydroxybutyl chitosan (HBC) may improve postoperative sequala following M3 removal.

Purpose

The study purpose was to measure and compare differences in pain, swelling, trismus, wound healing, and quality of life (QOL) between the HBC and the control sides in patients undergoing M3 removal.

Study Design, Setting, Sample

This study is a double-blind, split-mouth, randomized clinical trial. Patients who required M3 removal between June 2022 and May 2023 were included. Exclusion criteria included seafood allergies, smoking, poor oral hygiene, and systemic diseases.

Predictor Variable

The predictor variable was the socket treatment technique. Subjects were randomly assigned to the HBC or control (physiological saline) side.

Main Outcome Variable

The primary outcome variables, including pain assessed by visual analog scale, swelling, and maximal incisional opening, were measured on the first, third, and seventh postoperative days. The secondary outcome variables included QOL and wound healing score measured on the third and seventh days after surgery.

Covariates

The covariates included age, sex, and operation time.

Analyses

The Shapiro‒Wilk test was used to evaluate the normality of the data distribution. The paired t test or Wilcoxon signed-rank test was adopted. Statistical significance was set at P < .05.

Results

The study included 60 patients (mean age: 25.81 ± 4.91; 23 (38%) males, 37 (62%) females). A statistically significant difference in the level of pain (HBC: 37.58 ± 4.39 mm, control: 47.00 ± 4.33 mm, day 1, P < .001; 21.88 ± 3.25 mm, 35.95 ± 1.57 mm, day 3, P < .001), maximal incisional opening (23.92 ± 1.38 mm, 18.22 ± 1.82 mm, day 1, P < .001; 30.00 ± 1.61 mm, 23.78 ± 1.70 mm, day 3, P < .001), and swelling (6.86 ± 0.70 mm, 7.15 ± 0.80 mm, day 3, P = .006) was detected after surgery. A statistically significant difference in QOL was detected (HBC: 13.70 ± 1.65, control: 18.60 ± 2.14, day 3, P < .001).

Conclusion and Relevance

The application of HBC hydrogels to wounds after impacted mandibular M3 extraction reduces postoperative sequalae, promotes wound healing and improves postoperative QOL.
背景:目的:本研究的目的是测量和比较羟丁基壳聚糖(HBC)和对照组之间在M3拔除术患者的疼痛、肿胀、践踏、伤口愈合和生活质量(QOL)方面的差异:本研究是一项双盲、分口、随机临床试验。研究对象包括 2022 年 6 月至 2023 年 5 月期间需要切除 M3 的患者。排除标准包括海鲜过敏、吸烟、口腔卫生不良和全身性疾病:预测变量为插座治疗技术。受试者被随机分配到 HBC 或对照组(生理盐水)一侧:主要结果变量包括通过视觉模拟量表评估的疼痛、肿胀和切口最大张开度,在术后第一天、第三天和第七天进行测量。次要结果变量包括术后第三天和第七天的 QOL 和伤口愈合评分:协变量包括年龄、性别和手术时间:分析:采用 Shapiro-Wilk 检验评估数据分布的正态性。采用配对 t 检验或 Wilcoxon 符号秩检验。统计显著性以 P 为标准:研究共纳入 60 名患者(平均年龄:25.81 ± 4.91;男性 23 人(38%),女性 37 人(62%))。疼痛程度(HBC:37.58 ± 4.39 mm,对照组:47.00 ± 4.33 mm,第 1 天,P 结论和相关性:在下颌 M3 嵌顿拔牙后的伤口上使用 HBC 水凝胶可减少术后后遗症、促进伤口愈合并改善术后 QOL。
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引用次数: 0
AAOMS Author Disclosure forms
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/S0278-2391(24)00716-X
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引用次数: 0
Reply: The Triple Threat: The Quintessential Goal of Faculty Development 答复三重威胁:教师发展的五大目标
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.joms.2024.06.160
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引用次数: 0
Patient-specific Implants Improve Volumetric Surgical Accuracy Compared to Stock Reconstruction Plates in Modern Paradigm Virtual Surgical Planning of Fibular Free Flaps for Head and Neck Reconstruction 在现代 Pardigm 头颈部重建腓骨游离瓣虚拟手术规划中,与库存重建板相比,患者特异性植入物提高了容积手术精度。
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.joms.2024.06.166
<div><h3>Background</h3><div>Virtual surgical planning (VSP) for composite microvascular free flaps<span> has become standard of care for oncologic head and neck reconstruction. Controversy remains as to the use of three-dimensional (3D)-printed patient-specific titanium implants (PSIs) versus hand-bent stock reconstruction plates. Proponents of PSIs cite improved surgical accuracy, reduced operative times, and improved clinical outcomes. Detractors purport increased cost associated with PSIs and presumed equivalent accuracy with less expensive stock plates.</span></div></div><div><h3>Purpose</h3><div>The study purpose was to measure and compare the 3D-volumetric accuracy of PSI versus stock reconstruction plates among subjects undergoing VSP-guided mandibular fibular free flap reconstruction.</div></div><div><h3>Study Design, Setting, Sample</h3><div>A retrospective cohort study of subjects undergoing VSP-guided fibular free flap reconstructions at Mayo Clinic between 2016 and 2023 was performed. Subjects were excluded for non-VSP guidance, midfacial reconstruction, nonfibular free flaps, and lack of requisite study variables.</div></div><div><h3>Predictor Variable</h3><div>The primary predictor was the type of reconstruction plate utilized (PSI vs stock plate).</div></div><div><h3>Main Outcome Variable</h3><div>The main outcome was volumetric surgical accuracy of the final reconstruction compared to the preoperative surgical plan by root mean square error (RMSE) calculation. Lower RMSE values indicated a higher surgical accuracy.</div></div><div><h3>Covariates</h3><div>Covariates included age, sex, race, smoking status, American Society of Anesthesiologists (ASA) Physical Status Classification System, Charlson Comorbidity Index, preoperative diagnosis, and number of fibular segments.</div></div><div><h3>Analyses</h3><div>Differences in surgical accuracy were assessed between preoperative and postoperative segmented scans using volumetric overlays from which RMSE values were calculated. Univariate and multivariate modeling of plate type to RMSE calculation was performed. Statistical significance set to <em>P</em> < .05.</div></div><div><h3>Results</h3><div>Total of 130 subjects were identified, 105 PSI and 25 stock plates. Calculated mean RMSE in millimeters (mm) for stock plates was 1.46 (standard deviation: 0.33) and 1.15 (standard deviation: 0.36) for PSIs. Univariate modeling demonstrated a statistically significant difference in RMSE of 0.31 (95% confidence interval: 0.16-0.47) (<em>P</em> < .001) equating to a 21.2% (<em>P</em> < .001) improved volumetric surgical accuracy for PSIs. The association of improved volumetric accuracy with PSIs has been maintained in all multivariate models controlling for confounding.</div></div><div><h3>Conclusion and Relevance</h3><div>In modern era VSP-guided head and neck fibular free flap reconstruction, patient-specific 3D-printed titanium implants confer a statistically significant improvement
背景:复合微血管游离瓣的虚拟手术规划(VSP)已成为头颈部肿瘤重建的标准治疗方法。关于使用三维(3D)打印的钛合金患者特异性植入物(PSI)还是手工弯曲的重建板,目前仍存在争议。PSIs 的支持者认为可以提高手术准确性、缩短手术时间并改善临床效果。目的:该研究的目的是测量和比较在 VSP 引导下进行下颌腓骨游离瓣重建的受试者使用 PSI 与普通重建板的三维容积精度:对2016年至2023年期间在梅奥诊所接受VSP引导下下颌腓骨游离瓣重建术的受试者进行回顾性队列研究。排除了非VSP引导、中面部重建、非腓骨游离瓣以及缺乏必要研究变量的受试者:主要预测因素是所使用的重建板类型(PSI 板与普通板):主要结果是通过均方根误差(RMSE)计算得出的最终重建与术前手术计划相比的体积手术准确性。RMSE值越低,手术准确性越高:协变量包括年龄、性别、种族、吸烟状况、美国麻醉医师协会身体状况分类系统、查尔森综合指数、术前诊断和腓骨节段数:使用容积重叠法评估术前和术后分段扫描的手术准确性差异,并计算RMSE值。根据RMSE计算结果对钢板类型进行单变量和多变量建模。统计显著性设定为 P 结果:共确定了 130 个受试者,105 个 PSI 和 25 个库存平板。以毫米(mm)为单位计算的原板平均 RMSE 为 1.46(标准偏差:0.33),PSI 为 1.15(标准偏差:0.36)。单变量模型显示,RMSE 的差异为 0.31(95% 置信区间:0.16-0.47),具有统计学意义(P 结论及相关性:在现代 VSP 引导下的头颈部腓骨游离瓣重建中,患者特制的 3D 打印钛植入物与库存重建板相比,在体积手术准确性方面具有统计学意义的显著改善。
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引用次数: 0
Can a Low-Fidelity Arthroscopic Simulator Improve Technical Expertise in Performing Temporomandibular Joint Arthroscopy? 低保真关节镜模拟器能否提高颞下颌关节镜手术的专业技术水平?
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.joms.2024.06.180

Background

Challenges in temporomandibular joint (TMJ) arthroscopy training include the cost of operating room time, surgical risks, and the accessibility of cadavers and high-fidelity simulators. A low-fidelity simulator (LFS) was developed for initial TMJ arthroscopy training.

Purpose

The aim of this study was to evaluate improvement in TMJ arthroscopic skills after training with an LFS using the Arthroscopic Surgical Skill Evaluation Tool (ASSET) global rating scale.

Study Design, Setting, Sample

A prospective randomized controlled study was conducted. Subjects included Oral and Maxillofacial Surgery residents in postgraduate year 1–5 at Thomas Jefferson University. Chief residents actively performing TMJ arthroscopy were excluded.

Predictor Variable

The predictor variable was participation in LFS training. Subjects were randomly assigned to the LFS training or no LFS training group.

Main outcome Variables

The primary outcome variable was simulated surgical skill measured by total ASSET score (maximum score of 35). The secondary outcome variables were simulated surgical skill measured by each ASSET domain score and time to completion.

Covariates

The covariates included sex, age, handedness, postgraduate year, endoscopic experience, open TMJ surgery experience, and experience with musical instruments and sports.

Analyses

Data analyses included paired T-tests to determine changes in outcome variables after TMJ arthroscopy training between experimental groups, and ANOVA and χ2 tests to identify associations between covariates. Inter-rater reliability of the blinded examiners was evaluated using Cronbach's alpha correlation. A P-value < .05 was considered significant.

Results

The sample was composed of 10 residents: 5 (100%) males in the no LFS group, 3 (60%) males, and 2 (40%) females in the LFS group (P = .4). There was no significant difference between the groups in pre-TMJ arthroscopy training ASSET scores (P = .3). After training, the total ASSET score improved by 3.40 ± 6.87 in the no LFS group and by 6.27 ± 2.68 in the LFS group (P = .03).

Conclusions and Relevance

Study results showed that low-fidelity simulation can improve fundamental arthroscopic skills. Future research should be conducted on a larger scale to further validate this model and show the transfer of skill improvements to cadaver and live patient settings.
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引用次数: 0
Artificial Intelligence in Medicine: Is Oral and Maxillofacial Surgery Following the Trend? 人工智能在医学中的应用:口腔颌面外科是否紧跟潮流?
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.joms.2024.05.042
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引用次数: 0
Predicting the Future Focus of Orthognathic Surgery: Outcome-Driven Planning and Treatment With Function, Esthetics, and Occlusion as Key Indicators 口腔颌面外科杂志特别贡献 预测正颌外科的未来重点:以功能、美学和咬合为关键指标的成果驱动型规划和治疗。
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.joms.2024.06.168
As an international group of orthognathic surgeons, we believe the next big thing in orthognathic surgery will be a clinical and research focus on patient-oriented outcomes and improved quality of life. We expect to see advances in diagnosis and treatment planning, materials development, and patient management.
自 Trauner 和 Obwegeser 首次描述现代正颌外科手术(OGS)以来,我们已经走过了七十年的历程。我们当然承认 Hullihen 在 1849 年和其他学者在 20 世纪 20 和 30 年代的贡献,以及 Tessier、Obwegeser 和 Bell 在 20 世纪 60 和 70 年代的开创性工作。尽管在截骨设计方面已经发生了一些变化,并且在 20 世纪 70 年代和 80 年代引入了改变游戏规则的硬质内固定,但最近的许多重大变化都是在过去 10 年或 20 年才发生的。个性化和精准医疗与虚拟手术规划以及患者特异性植入物的应用已经发生了变革。当然,在诊断、手术技术和方案、生物材料和组织工程以及外科医生和患者教育等领域还会有更多进步。但是,作为一个国际正颌外科医生团体,我们认为最重要的 "下一件大事 "是将临床和研究重点放在以患者为导向的结果和生活质量的提高上。这将需要以结果为导向的规划和治疗,并将功能、美学和咬合作为关键的结果指标。在此,我们确定了 OGS 的一些共同愿景和目标,旨在划定未来的发展方向,以加强对牙颌面畸形患者的治疗。虽然我们对各章节进行了组织,以涵盖关键领域,但基本概念包括这些领域的进展:诊断和治疗计划(例如,成像、虚拟手术计划、人工智能和护理点工作流程);材料开发(例如,患者专用种植体、三维打印、组织工程、生物可降解种植体、骨水泥、钛和镁种植体以及发育和再生医学);以及患者管理(例如,微创手术、透明矫治器治疗、临时固定装置、门诊 OGS、以年龄为中心的治疗以及增强现实/虚拟现实)。
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引用次数: 0
RE: “Ultrasound-Guided Suprazygomatic Maxillary Nerve Block Is Effective in Reducing Postoperative Opioid Use Following Bimaxillary Osteotomy” RE: "超声引导下的颧上颌神经阻滞能有效减少双颌截骨术后阿片类药物的用量" RE: "Ultrasound-Guided Suprazygomatic Maxillary Nerve Block Is Effective in Reducing Postoperative Opioid Use Following Bimaxillary Osteotomy
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.joms.2024.05.043
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引用次数: 0
Are Radiographic Changes in the Mandibular Canal Associated With Bone Mineral Density? 下颌窦的射线变化与骨密度有关吗?
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/j.joms.2024.06.167

Background

Osteoporosis, highly prevalent among postmenopausal women, significantly reduces bone density and increases the risk of fractures. Cortical bone, which constitutes the largest calcium deposit in the human skeleton, is primarily affected in various conditions, including osteoporosis. Due to its visibility in panoramic radiography, the cortical area of the mandibular canal could be valuable in assessing decreases in bone mineral density (BMD).

Purpose

The study aimed to characterize and compare changes in the cortices of the mandibular canal between normal, osteopenic, and osteoporotic postmenopausal women.

Study Design, Setting, Sample

Our cross-sectional study analyzed postmenopausal patients. We included only patients with panoramic radiographs with good quality and who underwent osteoporosis risk assessment by dual-energy x-ray absorptiometry (DXA).

Independent Variable

BMD was measured by DXA at 3 sites (spine, femur, and forearm) and used to classify the patients into normal, osteopenic, or osteoporotic. This classification remained consistent across all measurement sites.

Main Outcome Variable

The main outcome variable was BMD of the mandibular canal cortices measured using black pixel intensity.

Covariates

Demographic covariates, including age, weight, height, and BMD, were assessed.

Analyses

One-way analysis of variance between groups considering a P < .05. The relationship between covariates and dependent variables was assessed using the Pearson correlation test.

Results

The sample comprised 52 postmenopausal women aged more than 40 years (mean age 61 ± 10 years), 26 (50%) normal, 18 (35%) osteopenic, and 8 (15%) osteoporotic. Significant differences were observed in the percentage of black pixels in the mandibular ramus between the groups. In this region, the average percentage of black pixels was 3.19% (± 0.65) for the normal group, 2.78% (± 0.65) for the osteopenia group, and 2.35% (± 0.65) for the osteoporosis group (P = .015). No significant differences were found in other mandibular regions.

Conclusion and Relevance

Our findings demonstrate an association between BMD assessed in the mandibular canal cortex and the presence of osteoporosis as determined by DXA. While the observed differences in black pixel percentages in the mandibular ramus are minor, they are statistically significant, suggesting that panoramic radiography may serve as an adjunctive tool for osteoporosis screening.
背景:骨质疏松症是绝经后妇女的高发病,会大大降低骨密度,增加骨折风险。皮质骨是人体骨骼中最大的钙沉积物,主要受骨质疏松症等各种疾病的影响。由于下颌管皮质区在全景X光片中的可见性,它对评估骨矿密度(BMD)的下降很有价值。研究目的:本研究旨在描述和比较正常、骨质疏松和骨质疏松绝经后妇女下颌管皮质的变化:我们的横断面研究分析的是绝经后患者。研究设计:我们的横断面研究对绝经后患者进行了分析。我们只纳入了全景X光片质量良好且通过双能X光吸收测量法(DXA)进行了骨质疏松症风险评估的患者:独立变量:通过 DXA 测量 3 个部位(脊柱、股骨和前臂)的 BMD,并将患者分为正常、骨质疏松和骨质疏松症。这一分类在所有测量部位都保持一致:主要结果变量是使用黑色像素强度测量的下颌管皮质的 BMD:对包括年龄、体重、身高和 BMD 在内的人口统计学协变量进行了评估:分析:组间单因素方差分析,考虑 P 结果:样本包括 52 名年龄超过 40 岁的绝经后妇女(平均年龄为 61 ± 10 岁),其中 26 人(50%)正常,18 人(35%)骨质疏松,8 人(15%)骨质疏松。在下颌骨横梁黑色像素的百分比方面,各组之间存在显著差异。在该区域,正常组黑色像素的平均百分比为 3.19%(± 0.65),骨质疏松组为 2.78%(± 0.65),骨质疏松症组为 2.35%(± 0.65)(P = .015)。其他下颌骨区域未发现明显差异:我们的研究结果表明,下颌管皮质评估的 BMD 与 DXA 确定的骨质疏松症存在关联。虽然观察到的下颌骨横梁黑色像素百分比差异较小,但在统计学上具有显著意义,这表明全景放射摄影可作为骨质疏松症筛查的辅助工具。
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引用次数: 0
Editorial Board Page
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-10-01 DOI: 10.1016/S0278-2391(24)00714-6
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引用次数: 0
期刊
Journal of Oral and Maxillofacial Surgery
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