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February 2025 AAOMS News and Announcements
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-02-01 DOI: 10.1016/j.joms.2024.11.002
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引用次数: 0
Coronectomy in Lower Third Molar Surgery: A Systematic Review and Meta-Analysis.
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-31 DOI: 10.1016/j.joms.2025.01.014
Fei Wu Kang, Guang Yu Hou, Xue Ming Zhang, Yang Yi Fan Zhou, Gong Cheng Li, Xin Rui Yuan

Purpose: Coronectomy is an alternative approach to the complete removal of an impacted mandibular third molar. The present study conducted a systematic review and meta-analysis to compare coronectomy with extraction concerning complications associated with the inferior alveolar nerve injury (IANI).

Methods: This review followed the principles of systematic reviews and meta-analyses. We conducted a comprehensive literature search of 5 databases according to PRISMA guidelines. Research articles published in English before April 30, 2024 were reviewed. The keywords consisted of "coronectomy and lower third molar." In this study, Rayyan online software was used to identify and eliminate duplicate articles, and another reviewer was invited to screen the articles independently. The included articles' data were extracted, and conclusions were drawn after cross-comparison. The forest plot was drawn after analysis by the R program (JJ Allaire, Boston, Massachusetts, USA). The primary outcome variable of the present study was evaluating the incidence of IANI, and secondly, the lingual nerve injury (LNI), dry socket, postoperative infection, the necessity for surgical reintervention, root migration, root extraction, and coronectomy failure rate. These assessments were made concerning patients' chosen operative technique for managing third molars, either coronectomy or extraction, as predictor variables.

Results: After applying inclusion and exclusion criteria, 34 of the 564 articles were included in this study (24 cohort studies and 10 case‒control studies), with 7,115 wisdom teeth from 4,477 patients in different countries. Meta-analysis showed that coronectomy reduced the risk of IANI: relative risk (RR): 0.1; 95% confidence interval (CI): 0.0-0.2; I2 (inconsistency index) = 0%; P < .0001, the risk of LNI (RR: 0.2; 95% CI: 0.0-0.7; I2 = 0%; P = .01), dry socket (RR: 0.4; 95% CI: 0.3-0.7; I2 = 0%; P = .002), and postoperative infection (RR: 1.0; 95% CI: 0.5-2.1; I2 = 27%; P = .9). However, coronectomy exhibited a higher risk of surgical reintervention of 3.63% (111 of 3,055), root exposure of 2.66% (61 of 2,290), and a specific failure rate of 2.79% (119 of 4,261).

Conclusion: When the mandibular third molar with a higher risk of IANI needs to be removed, coronectomy can reduce the risk of IANI and LNI and the incidence of dry socket compared with traditional extraction. There was no significant difference in postoperative infection between the 2 groups. However, coronectomy exhibited a specific failure rate and higher odds of secondary surgical intervention. Guided bone regeneration can slow down the movement of residual roots and reduce the incidence of secondary surgery.

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引用次数: 0
Five-Year Experience With Routine Use of Intraoperative Cone-Beam Computed Tomography in Zygomaticomaxillary Complex Fractures.
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-30 DOI: 10.1016/j.joms.2025.01.013
Dominique Korner, Daphne Schönegg, Daniel Wiedemeier, Maximilian Eberhard Hermann Wagner, Harald Essig, Michael Blumer

Background: Intraoperative cone-beam computed tomography (CBCT) during open reduction and internal fixation of zygomaticomaxillary complex (ZMC) fractures may facilitate the re-establishment of a complex 3-dimensional anatomy.

Purpose: This study was conducted to measure the occurrence of malpositions after ZMC fracture reduction and intraoperative revision rates after conducting intraoperative CBCT.

Study design, setting, sample: This retrospective case series included subjects treated for ZMC fractures with intraoperative CBCT at the Department of Maxillofacial Surgery of the University Hospital Zurich (Switzerland) over a 5-year period (January 2015 to December 2019). The exclusion criteria were a history of facial fracture and incomplete data.

Predictor variable: Not applicable.

Main outcome variables: The primary outcome variable was malpositioning after ZMC fracture reduction on intraoperative 3-dimensional imaging. Further variables-including intraoperative revisions of ZMC malpositions, osteosynthesis material revisions, and intraoperative assessments of orbital reconstruction-were analyzed.

Covariates: Demographic (age and sex) and clinical (associated with facial fractures) characteristics were assessed.

Analyses: The analyses included Spearman's rank correlations, mosaic plots, χ2 tests, and Fisher's exact tests. The confidence level for hypothesis testing was set at P < .05.

Results: The sample included 337 subjects, and 589 intraoperative CBCT scans were obtained. ZMC malposition after reduction was observed in 154 (45.7%) subjects; the most common malpositions were caudal displacement, underprojection, and inward rotation of the ZMC. Intraoperative revisions were conducted in 150 (44.5%) subjects: 105 (31.2%) subjects exhibited a ZMC malposition, 13 (3.9%) subjects needed revisions of the osteosynthesis material placement, and 32 (9.5%) subjects required intraoperative orbital floor reconstruction. No secondary revision surgeries were required, excluding 25 secondary orbital floor reconstructions. Preoperative and intraoperative CBCT findings did not correlate regarding indications for orbital floor reconstruction.

Conclusion and relevance: The 44.5% intraoperative revision rate underscores the challenges of ZMC fracture surgery. Clinical evaluation of fracture reduction at the latero-orbital rim is recommended to identify caudal displacements, and intraoperative CBCT helps identify candidates for primary orbital floor reconstruction. This technique may enhance quality control and precision, thereby potentially improving patient outcomes.

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引用次数: 0
Patient-Reported Outcomes With Focus on Health-Related Quality of Life in Patients With Obstructive Sleep Apnea Treated With Maxillomandibular Advancement Surgery: A Systematic Review and Meta-Analysis.
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-28 DOI: 10.1016/j.joms.2025.01.010
Haya H R Al-Bayyati, Gert-Jan Hassing, Egbert P van der Hoeve, Laurens Koppendraaier, Maurits H T de Ruiter

Purpose: Maxillomandibular advancement (MMA) surgery for obstructive sleep apnea (OSA) has shown to be effective according to objective measures; however, patient-reported outcome measurements (PROMs), especially health-related quality of life (HRQoL), are also crucial but have not been systematically assessed in relation to MMA surgery for OSA yet. Therefore, this study aims to conduct a systematic review on the effect of MMA surgery on PROMs focusing on HRQoL in patients with OSA.

Methods: A systematic review and meta-analysis were conducted following the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines with a literature search performed in PubMed and Medline to identify relevant studies from database inception to May 2024 evaluating PROMs focusing on HRQoL in adult OSA patients treated with MMA surgery. The primary variables are the PROMs outcomes. Screening and eligibility assessments were carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis framework, and study quality was evaluated using the ROBINS-I tool. The data extraction for the meta-analysis included PROMs outcomes and was carried out in SPSS using a fixed-effects model to report effect sizes as mean differences.

Results: Thirty-three studies were screened of which 12 were included in this systematic review encompassing 317 patients. The studies reported PROMs in a heterogeneous manner, but MMA consistently showed an improvement postoperatively in mean differences. In the most used PROMs instruments MMA surgery was associated with a 5.35-point improvement in the Epworth Sleepiness Scale (95% CI -6.57 to -4.14; Z = -8.62; P < .001), a 3.96-point improvement on the Functional Outcomes of Sleep Questionnaire (95% CI 3.11, 4.80; Z = 11.60; P < .001) and an improvement in all domains of the Short Form 36 Health Survey.

Conclusion: MMA surgery for patients with OSA shows significant improvements in PROMs related to quality of life. The PROMs are positive, demonstrating satisfaction across various domains. This indicates that MMA surgery is well received by patients and results in clinically meaningful improvements in PROMs related to HRQoL.

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引用次数: 0
Stress-Related Personality Patterns in Patients With Dentofacial Deformities and Their Evolution After Orthognathic Surgery.
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-28 DOI: 10.1016/j.joms.2025.01.011
Nur Altıparmak, Sıdıka Sinem Akdeniz, Ezgi Ergezen, Alaz Enez

Background: Orthognathic surgery significantly influences psychosocial well-being. Individuals with dentofacial deformities may experience psychological distress, characterized by negative affectivity (NA) and social inhibition (SI). When these 2 traits coexist, they define Type D personality.

Purpose: The aim of this study was to estimate the prevalence of Type D personality traits in patients with Class III dentofacial deformities and assess changes in these traits, which inherently reflect variations in Type D personality, following orthognathic surgery.

Study design, setting, sample: This prospective cohort study was conducted at Başkent University Department of Oral and Maxillofacial Surgery between November 2022 and March 2024. Sociodemographic data and psychological assessments were collected using the Type D Scale-14 preoperatively and 3 months postoperatively.

Predictor: The predictor variable was the preoperative personality trait, measured using the validated Type D Scale-14 questionnaire. This questionnaire comprises the following 2 subscales: NA and SI, each consisting of 7 items. Responses are scored from 0 to 4, resulting in scores ranging from 0 to 28. A score of ≥10 on both NA and SI subscales indicates a Type D personality.

Outcome variable: The primary outcome variable was the postoperative personality trait, specifically changes in NA and SI, measured using the Type D Scale-14. The secondary outcomes were the prevalence of Type D personality traits before and after surgery.

Covariates: The covariates were age, sex, marital status, and employment status.

Analyses: Descriptive statistics and paired t-tests were performed to assess the differences between preoperative and postoperative results. A P value of <.05 was considered statistically significant.

Results: The study sample comprised 41 participants (mean age: 22.24 ± 4.72 years), 65.9% (n = 27) of whom were female. The prevalence of Type D personality traits significantly decreased from 42.9% (n = 18) preoperatively to 17.1% (n = 7) postoperatively (P < .05). When the subscales of NA and SI were examined, both scores showed statistically significant reductions (P < .05).

Conclusions: Significant differences were observed in NA and SI before and after orthognathic surgery. This study represents the first application of the Type D Scale-14 in the context of orthognathic surgery. Observed psychological improvement highlights the importance of preoperatively assessing patients' psychosocial conditions.

背景:正颌外科手术严重影响社会心理健康。牙颌面畸形患者可能会经历心理困扰,其特点是消极情绪(NA)和社交抑制(SI)。目的:本研究的目的是估算Ⅲ度颌面部畸形患者中D型人格特质的流行率,并评估这些特质在正颌手术后的变化,这些特质本质上反映了D型人格的变异:这项前瞻性队列研究于2022年11月至2024年3月在巴什肯特大学口腔颌面外科进行。使用 D 型量表-14 收集术前和术后 3 个月的社会人口学数据和心理评估:预测变量是术前人格特质,使用经过验证的 D 型量表-14 问卷进行测量。该问卷由以下两个分量表组成:NA和SI,每个分量表由7个项目组成。回答从 0 到 4 分,得分从 0 到 28 分不等。如果 NA 和 SI 两个分量表的得分均≥10 分,则表明患者属于 D 型人格:主要结果变量是术后人格特质,特别是 NA 和 SI 的变化,使用 D 型人格量表-14 进行测量。次要结果是手术前后 D 型人格特质的患病率:协变量:年龄、性别、婚姻状况和就业状况:分析:采用描述性统计和配对 t 检验来评估术前和术后结果之间的差异。结果研究样本包括 41 名参与者(平均年龄:22.24 ± 4.72 岁),其中 65.9% (n = 27)为女性。D型人格特征的患病率从术前的42.9%(n = 18)明显降低到术后的17.1%(n = 7)(P 结论:D型人格特征的患病率从术前的42.9%(n = 18)明显降低到术后的17.1%(P):正颌手术前后,NA 和 SI 存在明显差异。本研究是 D 型量表-14 在正颌外科手术中的首次应用。观察到的心理改善凸显了术前评估患者社会心理状况的重要性。
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引用次数: 0
Monoclonal Antibodies and Small-Molecule Inhibitors Associated Osteonecrosis of Jaw: A Retrospective Pharmacovigilance Study.
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-22 DOI: 10.1016/j.joms.2025.01.008
Kannan Sridharan, Gowri Sivaramakrishnan
<p><strong>Background: </strong>Osteonecrosis of the jaw (ONJ) is an adverse effect associated with medications such as monoclonal antibodies and small-molecule inhibitors.</p><p><strong>Purpose: </strong>This study assesses the association between monoclonal antibodies and small-molecule inhibitors with ONJ.</p><p><strong>Study design, setting, sample: </strong>The study design was a retrospective pharmacovigilance case series. The sample was derived from the United States Food and Drug Administration Adverse Event Reporting System database reporting ONJ from March 2004 to March 2024. The inclusion criteria were the reports relating ONJ occurrence with exposure to monoclonal antibodies (trastuzumab, bevacizumab, denosumab, elotuzumab, isatuximab, pertuzumab, ramucirumab, romosozumab, and ado-trastuzumab emtansine) and small-molecule inhibitors (abemaciclib, alpelisib, axitinib, cabozantinib, lapatinib, lenvatinib, palbociclib, ribociclib, and sunitinib). The exclusion criteria were the reports associating the role of monoclonal antibodies and small molecule inhibitors to ONJ with roles other than primary suspicion.</p><p><strong>Predictor variable: </strong>Not applicable.</p><p><strong>Main outcome variable: </strong>The outcome variable is the case status divided into case and noncase. Cases were defined as reports with ONJ associated with monoclonal antibodies or small-molecule inhibitors while noncases were the reports with other adverse events. Secondary outcome variables were death, hospitalization, and disability observed with monoclonal antibodies/small-molecule inhibitors-associated ONJ.</p><p><strong>Covariates: </strong>Age and gender were the covariates included in this study.</p><p><strong>Analyses: </strong>The case-noncase approach was applied for signal detection, using frequentist (reporting odds ratio [ROR] and proportional reporting ratio [PRR]) and Bayesian methods (lower limit of 95% CI of Information component [IC025]). The ROR is determined by comparing the odds of ONJ being reported for a given drug to the odds of the same event being reported for all other drugs and PRR is estimated by the ratio of proportion of reports for a specific drug with ONJ over the proportion of reports with ONJ for all other drugs. The information component is defined as defined as the logarithmic ratio of the observed ONJ with the primary suspected drug relative to the expected frequency of the drug-ONJ pair based on overall reporting rates in the database. Outcomes were analyzed with statistical comparisons using χ<sup>2</sup> tests (χ2) at P ≤ .05.</p><p><strong>Results: </strong>A total of 7,402 reports were included with median age ranging between 61 and 76 years with female preponderance. Denosumab (ROR: 64.7 [62.5, 67]; PRR: 61.9 [59.9, 64.1]; P < .05; and IC025: 5.1), romosozumab (ROR 4.2 [3, 6]; PRR: 4.2 [3, 6]; P < .05; and IC025: 1.5), and lenvatinib (ROR: 3.1 [2.3, 4.2]; PRR: 3.1 [2.3, 4.1]; P < .05; and IC025: 1.2) showed positive
{"title":"Monoclonal Antibodies and Small-Molecule Inhibitors Associated Osteonecrosis of Jaw: A Retrospective Pharmacovigilance Study.","authors":"Kannan Sridharan, Gowri Sivaramakrishnan","doi":"10.1016/j.joms.2025.01.008","DOIUrl":"10.1016/j.joms.2025.01.008","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Osteonecrosis of the jaw (ONJ) is an adverse effect associated with medications such as monoclonal antibodies and small-molecule inhibitors.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;This study assesses the association between monoclonal antibodies and small-molecule inhibitors with ONJ.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study design, setting, sample: &lt;/strong&gt;The study design was a retrospective pharmacovigilance case series. The sample was derived from the United States Food and Drug Administration Adverse Event Reporting System database reporting ONJ from March 2004 to March 2024. The inclusion criteria were the reports relating ONJ occurrence with exposure to monoclonal antibodies (trastuzumab, bevacizumab, denosumab, elotuzumab, isatuximab, pertuzumab, ramucirumab, romosozumab, and ado-trastuzumab emtansine) and small-molecule inhibitors (abemaciclib, alpelisib, axitinib, cabozantinib, lapatinib, lenvatinib, palbociclib, ribociclib, and sunitinib). The exclusion criteria were the reports associating the role of monoclonal antibodies and small molecule inhibitors to ONJ with roles other than primary suspicion.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Predictor variable: &lt;/strong&gt;Not applicable.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main outcome variable: &lt;/strong&gt;The outcome variable is the case status divided into case and noncase. Cases were defined as reports with ONJ associated with monoclonal antibodies or small-molecule inhibitors while noncases were the reports with other adverse events. Secondary outcome variables were death, hospitalization, and disability observed with monoclonal antibodies/small-molecule inhibitors-associated ONJ.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Covariates: &lt;/strong&gt;Age and gender were the covariates included in this study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Analyses: &lt;/strong&gt;The case-noncase approach was applied for signal detection, using frequentist (reporting odds ratio [ROR] and proportional reporting ratio [PRR]) and Bayesian methods (lower limit of 95% CI of Information component [IC025]). The ROR is determined by comparing the odds of ONJ being reported for a given drug to the odds of the same event being reported for all other drugs and PRR is estimated by the ratio of proportion of reports for a specific drug with ONJ over the proportion of reports with ONJ for all other drugs. The information component is defined as defined as the logarithmic ratio of the observed ONJ with the primary suspected drug relative to the expected frequency of the drug-ONJ pair based on overall reporting rates in the database. Outcomes were analyzed with statistical comparisons using χ&lt;sup&gt;2&lt;/sup&gt; tests (χ2) at P ≤ .05.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 7,402 reports were included with median age ranging between 61 and 76 years with female preponderance. Denosumab (ROR: 64.7 [62.5, 67]; PRR: 61.9 [59.9, 64.1]; P &lt; .05; and IC025: 5.1), romosozumab (ROR 4.2 [3, 6]; PRR: 4.2 [3, 6]; P &lt; .05; and IC025: 1.5), and lenvatinib (ROR: 3.1 [2.3, 4.2]; PRR: 3.1 [2.3, 4.1]; P &lt; .05; and IC025: 1.2) showed positive ","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic-Assisted Pterygomandibular Approach for Parapharyngeal Tumor Resection: A Case Series.
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-22 DOI: 10.1016/j.joms.2025.01.007
Xiaoqiong Wang, Lei Zheng, Bo Zheng, Xuejun Liu

Background: The endoscope-assisted pterygomandibular ligament approach for the resection of parapharyngeal space (PPS) tumors has been reported in a limited number of cases, with insufficiently detailed procedural descriptions.

Purpose: The study purpose was to report clinically relevant outcomes among patients who underwent endoscopy-assisted pterygomandibular ligament resection for PPS tumors.

Study design, setting, and sample: This study was a retrospective case series analyzing patients treated between January 2018 and July 2021 at the Department of Otolaryngology, Second Affiliated Hospital of Wenzhou Medical University. The sample consisted of patients who underwent endoscopy-assisted pterygomandibular ligament resection for PPS tumors. Patients with incomplete medical records or loss of follow-up were excluded.

Main outcome variable: The primary outcomes included successful tumor resection, intraoperative blood loss, operation duration, hospital stay, complications, recurrence, and follow-up duration.

Covariates: Demographic characteristics, tumor size, pathology, postoperative pain score were collected and analyzed.

Analyses: Data were summarized using descriptive statistics.

Results: The sample was composed of 9 patients (4 males, 5 females). The operation time ranged from 30 to 240 minutes, with operation blood loss between 5 and 200 mL. The average length of hospital stay was 8.45 days. The average pain score at the first postoperative day was 3.5. No complications, such as infection, bleeding, or nerve damage, were observed. No tumor recurrence was detected over a median follow-up of 53 months (interquartile range: 32.5).

Conclusion: The endoscope-assisted pterygomandibular ligament internal approach appears to be a good strategy for PPS tumor resection.

{"title":"Endoscopic-Assisted Pterygomandibular Approach for Parapharyngeal Tumor Resection: A Case Series.","authors":"Xiaoqiong Wang, Lei Zheng, Bo Zheng, Xuejun Liu","doi":"10.1016/j.joms.2025.01.007","DOIUrl":"10.1016/j.joms.2025.01.007","url":null,"abstract":"<p><strong>Background: </strong>The endoscope-assisted pterygomandibular ligament approach for the resection of parapharyngeal space (PPS) tumors has been reported in a limited number of cases, with insufficiently detailed procedural descriptions.</p><p><strong>Purpose: </strong>The study purpose was to report clinically relevant outcomes among patients who underwent endoscopy-assisted pterygomandibular ligament resection for PPS tumors.</p><p><strong>Study design, setting, and sample: </strong>This study was a retrospective case series analyzing patients treated between January 2018 and July 2021 at the Department of Otolaryngology, Second Affiliated Hospital of Wenzhou Medical University. The sample consisted of patients who underwent endoscopy-assisted pterygomandibular ligament resection for PPS tumors. Patients with incomplete medical records or loss of follow-up were excluded.</p><p><strong>Main outcome variable: </strong>The primary outcomes included successful tumor resection, intraoperative blood loss, operation duration, hospital stay, complications, recurrence, and follow-up duration.</p><p><strong>Covariates: </strong>Demographic characteristics, tumor size, pathology, postoperative pain score were collected and analyzed.</p><p><strong>Analyses: </strong>Data were summarized using descriptive statistics.</p><p><strong>Results: </strong>The sample was composed of 9 patients (4 males, 5 females). The operation time ranged from 30 to 240 minutes, with operation blood loss between 5 and 200 mL. The average length of hospital stay was 8.45 days. The average pain score at the first postoperative day was 3.5. No complications, such as infection, bleeding, or nerve damage, were observed. No tumor recurrence was detected over a median follow-up of 53 months (interquartile range: 32.5).</p><p><strong>Conclusion: </strong>The endoscope-assisted pterygomandibular ligament internal approach appears to be a good strategy for PPS tumor resection.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Association of Fracture Displacement and Surgical Intervention in Isolated Zygomatic Arch Fractures.
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-20 DOI: 10.1016/j.joms.2025.01.006
Margaret R Wang, Madeline G Chin, Damon R T McIntire, Kenny Chang, Leon Zhao, Daniel K Kwan

Background: In the evaluation of isolated zygomatic arch (ZA) fractures, a standardized guideline for recommending operative intervention is lacking.

Purpose: The study purpose was to measure the association between fracture displacement and operative treatment following isolated ZA fractures.

Study design, setting, sample: This is a retrospective cohort study identifying adult subjects with isolated ZA fractures presenting to the emergency department between September 2011 and October 2022. Subjects with non-ZA zygomaticomaxillary complex fractures or concurrent facial fractures were excluded.

Predictor/exposure/independent variable: The predictor is maximal fracture displacement in centimeters measured on axial computed tomography imaging.

Main outcome variable(s): The main outcome variable is operative management defined as recommendation of operative versus nonoperative intervention.

Covariates: Covariates collected include patient demographics; consisting of age, sex, past medical history (hypertension and diabetes); injury mechanism; social history (tobacco and alcohol use); presenting signs and symptoms (trismus, facial swelling, paresthesias, malar depression, and bony-step offs). Native overlying soft-tissue thickness was also measured on computed tomography imaging.

Analyses: Bivariate and multivariate statistical analyses were used to investigate differences between nonoperative and operative groups. Receiver operating characteristic curve was utilized to determine the discriminative fracture displacement for operative intervention. All statistical tests were performed with a significance level set at P < .05.

Results: The sample was composed of 86 subjects with an average age of 47.0 ± 19.1 years old. The mean fracture displacement was 0.29 ± 0.21 cm. Overall, 22 (25.6%) subjects were recommended operative intervention while 64 (74.4%) were managed nonoperatively. On bivariate analysis, mean fracture displacement was higher in the operative (0.51 ± 0.14 cm) versus nonoperative groups (0.21 ± 0.18 cm, P < .001). A significantly greater number of patients in the operative cohort presented with trismus, facial swelling and malar depression. Native soft-tissue thickness was not associated with operative intervention. On receiver operating characteristic curve analysis, the displacement that discriminated operative intervention was 0.36 cm with a sensitivity of 86.4% and specificity of 81.3% (area under the curve 0.9).

Conclusions and relevance: Isolated ZA fractures with a displacement of 0.36 cm or greater are associated with operative intervention. Measurement of fracture displacement may aid in clinical decision-making.

背景:目的:该研究旨在测量孤立性颧弓(ZA)骨折后骨折移位与手术治疗之间的关系:这是一项回顾性队列研究,研究对象为2011年9月至2022年10月期间在急诊科就诊的孤立性颧骨骨折成年患者。不包括非颧颌面复合体骨折或同时发生面部骨折的受试者:预测因子为轴向计算机断层扫描成像测量的最大骨折位移(以厘米为单位):主要结果变量:主要结果变量为手术治疗,即建议手术治疗与不手术治疗:收集的协变量包括患者人口统计学特征;包括年龄、性别、既往病史(高血压和糖尿病);受伤机制;社会史(吸烟和酗酒);出现的体征和症状(三趾挛缩、面部肿胀、麻痹、颧骨凹陷和骨质脱落)。计算机断层扫描成像还测量了原生上覆软组织的厚度:双变量和多变量统计分析用于研究非手术组和手术组之间的差异。利用接收者操作特征曲线来确定手术干预的骨折移位判别。所有统计检验的显著性水平均设定为 P 结果:样本由 86 名受试者组成,平均年龄(47.0±19.1)岁。平均骨折位移为 0.29 ± 0.21 厘米。总体而言,22 名受试者(25.6%)被建议接受手术治疗,64 名受试者(74.4%)接受非手术治疗。双变量分析显示,手术组(0.51 ± 0.14 厘米)与非手术组(0.21 ± 0.18 厘米,P)相比,平均骨折移位率更高:移位0.36厘米或更大的孤立ZA骨折与手术干预有关。测量骨折移位有助于临床决策。
{"title":"The Association of Fracture Displacement and Surgical Intervention in Isolated Zygomatic Arch Fractures.","authors":"Margaret R Wang, Madeline G Chin, Damon R T McIntire, Kenny Chang, Leon Zhao, Daniel K Kwan","doi":"10.1016/j.joms.2025.01.006","DOIUrl":"https://doi.org/10.1016/j.joms.2025.01.006","url":null,"abstract":"<p><strong>Background: </strong>In the evaluation of isolated zygomatic arch (ZA) fractures, a standardized guideline for recommending operative intervention is lacking.</p><p><strong>Purpose: </strong>The study purpose was to measure the association between fracture displacement and operative treatment following isolated ZA fractures.</p><p><strong>Study design, setting, sample: </strong>This is a retrospective cohort study identifying adult subjects with isolated ZA fractures presenting to the emergency department between September 2011 and October 2022. Subjects with non-ZA zygomaticomaxillary complex fractures or concurrent facial fractures were excluded.</p><p><strong>Predictor/exposure/independent variable: </strong>The predictor is maximal fracture displacement in centimeters measured on axial computed tomography imaging.</p><p><strong>Main outcome variable(s): </strong>The main outcome variable is operative management defined as recommendation of operative versus nonoperative intervention.</p><p><strong>Covariates: </strong>Covariates collected include patient demographics; consisting of age, sex, past medical history (hypertension and diabetes); injury mechanism; social history (tobacco and alcohol use); presenting signs and symptoms (trismus, facial swelling, paresthesias, malar depression, and bony-step offs). Native overlying soft-tissue thickness was also measured on computed tomography imaging.</p><p><strong>Analyses: </strong>Bivariate and multivariate statistical analyses were used to investigate differences between nonoperative and operative groups. Receiver operating characteristic curve was utilized to determine the discriminative fracture displacement for operative intervention. All statistical tests were performed with a significance level set at P < .05.</p><p><strong>Results: </strong>The sample was composed of 86 subjects with an average age of 47.0 ± 19.1 years old. The mean fracture displacement was 0.29 ± 0.21 cm. Overall, 22 (25.6%) subjects were recommended operative intervention while 64 (74.4%) were managed nonoperatively. On bivariate analysis, mean fracture displacement was higher in the operative (0.51 ± 0.14 cm) versus nonoperative groups (0.21 ± 0.18 cm, P < .001). A significantly greater number of patients in the operative cohort presented with trismus, facial swelling and malar depression. Native soft-tissue thickness was not associated with operative intervention. On receiver operating characteristic curve analysis, the displacement that discriminated operative intervention was 0.36 cm with a sensitivity of 86.4% and specificity of 81.3% (area under the curve 0.9).</p><p><strong>Conclusions and relevance: </strong>Isolated ZA fractures with a displacement of 0.36 cm or greater are associated with operative intervention. Measurement of fracture displacement may aid in clinical decision-making.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Liposomal Bupivacaine Reduce Postoperative Pain Following Third Molar Extractions? A Double-Blinded Randomized Controlled Trial.
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-17 DOI: 10.1016/j.joms.2025.01.004
Simon Youn, Katherine Scheker, Samuel Sheridan, Colin Hayashi, Trevor A Pickering, John Costandi

Background: Liposomal bupivacaine (LB) is a long-lasting local anesthetic providing analgesia for several days. The current literature examining the efficacy of LB in pain management following third molar extractions remains unclear.

Purpose: The purpose of this study was to compare postoperative pain management between LB and standard bupivacaine (SB) in mandibular third molar extractions.

Study design: A double-blinded randomized controlled trial of subjects undergoing bilateral mandibular third molar extractions at our institution from 2022 to 2024 was conducted using a split-mouth study design. Subjects were excluded if they received additional mandibular teeth extractions, were unable to complete the questionnaire, or had medical contraindications.

Predictor variable: The predictor variable was postsurgical local anesthetic agent, and the sides of mouth were randomly assigned to LB or SB.

Main outcome variable(s): Primary outcome was postoperative pain on a 10-point numerical rating scale (NRS), and the mean cumulative pain rating via area under the curve (AUC) analysis. Secondary outcomes were adverse events and ibuprofen or acetaminophen consumption.

Covariates: Demographics, procedure time, preoperative and perioperative local anesthetics used, and procedural difficulty coded as nonsurgical or surgical were collected.

Analyses: We used mixed-effects models to compare the NRS scores during each time period and paired t-tests to compare AUC values. Statistical tests included 95% CIs with alpha = 0.05.

Results: The study sample included 72 subjects (mean age 25.8, SD: 9). Pain was lower in the LB versus SB group on surgery day (NRS difference -0.75; P = .002) until the morning of postoperative day 2 (-0.68, P = .003). When limiting the analysis to bilateral surgical extractions, it was statistically significant until the morning of postoperative day 3 (-0.61, P = .02). AUC analysis showed cumulative pain reduction for the LB group in comparison to the SB group through all 4 postoperative days for the overall cohort (average AUC0-96 difference 93.5, P = .005), with a similar effect for bilateral surgical extractions (101.88, P = .006).

Conclusion: LB modestly reduces pain following third molar extractions, with this difference more pronounced following surgical extractions. This suggests that LB may be more beneficial in complex extractions and greater pain-inducing surgeries.

{"title":"Does Liposomal Bupivacaine Reduce Postoperative Pain Following Third Molar Extractions? A Double-Blinded Randomized Controlled Trial.","authors":"Simon Youn, Katherine Scheker, Samuel Sheridan, Colin Hayashi, Trevor A Pickering, John Costandi","doi":"10.1016/j.joms.2025.01.004","DOIUrl":"10.1016/j.joms.2025.01.004","url":null,"abstract":"<p><strong>Background: </strong>Liposomal bupivacaine (LB) is a long-lasting local anesthetic providing analgesia for several days. The current literature examining the efficacy of LB in pain management following third molar extractions remains unclear.</p><p><strong>Purpose: </strong>The purpose of this study was to compare postoperative pain management between LB and standard bupivacaine (SB) in mandibular third molar extractions.</p><p><strong>Study design: </strong>A double-blinded randomized controlled trial of subjects undergoing bilateral mandibular third molar extractions at our institution from 2022 to 2024 was conducted using a split-mouth study design. Subjects were excluded if they received additional mandibular teeth extractions, were unable to complete the questionnaire, or had medical contraindications.</p><p><strong>Predictor variable: </strong>The predictor variable was postsurgical local anesthetic agent, and the sides of mouth were randomly assigned to LB or SB.</p><p><strong>Main outcome variable(s): </strong>Primary outcome was postoperative pain on a 10-point numerical rating scale (NRS), and the mean cumulative pain rating via area under the curve (AUC) analysis. Secondary outcomes were adverse events and ibuprofen or acetaminophen consumption.</p><p><strong>Covariates: </strong>Demographics, procedure time, preoperative and perioperative local anesthetics used, and procedural difficulty coded as nonsurgical or surgical were collected.</p><p><strong>Analyses: </strong>We used mixed-effects models to compare the NRS scores during each time period and paired t-tests to compare AUC values. Statistical tests included 95% CIs with alpha = 0.05.</p><p><strong>Results: </strong>The study sample included 72 subjects (mean age 25.8, SD: 9). Pain was lower in the LB versus SB group on surgery day (NRS difference -0.75; P = .002) until the morning of postoperative day 2 (-0.68, P = .003). When limiting the analysis to bilateral surgical extractions, it was statistically significant until the morning of postoperative day 3 (-0.61, P = .02). AUC analysis showed cumulative pain reduction for the LB group in comparison to the SB group through all 4 postoperative days for the overall cohort (average AUC<sub>0-96</sub> difference 93.5, P = .005), with a similar effect for bilateral surgical extractions (101.88, P = .006).</p><p><strong>Conclusion: </strong>LB modestly reduces pain following third molar extractions, with this difference more pronounced following surgical extractions. This suggests that LB may be more beneficial in complex extractions and greater pain-inducing surgeries.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of Two Different Patient-Specific Drill/Cutting Guides for Maxillary Repositioning When Used for Minimally Invasive Bimaxillary Orthognathic Surgery.
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-01-10 DOI: 10.1016/j.joms.2025.01.001
Felix Jose Amarista, Edward Ellis

Background: Minimally invasive orthognathic surgery (MIOS) involves smaller incisions and minimal tissue dissection. Most MIOS is done using interim splints to position the first jaw. The application of patient-specific implants in MIOS is difficult due to the size of traditional cutting/drill guides, which require larger incisions. As a result, MIOS guides were redesigned for this study to fit into smaller incisions.

Purpose: The study purpose was to estimate and compare the accuracy of the smaller and redesigned bone-borne (BB) versus bone/tooth-borne (BTB) cutting/drilling guides used in minimally invasive bimaxillary orthognathic surgery.

Study design, setting, sample: This retrospective cohort study included consecutive MIOS patients treated by a single surgeon at the University of Texas Health San Antonio from June 2023 to September 2024. It included patients that underwent bimaxillary MIOS with complete preoperative and postoperative cone-beam computed tomographic records. Exclusion criteria included craniofacial syndromes, severe medical comorbidities, or single-jaw surgery.

Predictor variable: The primary predictor variable was the type of cutting/drilling guide (BB vs BTB) used to perform maxillary osteotomy.

Main outcome variable(s): The primary outcome variable was accuracy, defined as mean linear discrepancy that is closest to 0 mm. Linear discrepancies between planned and actual maxillary movements were measured.

Covariates: Demographics and malocclusion type.

Analyses: χ2 tests compared categorical variables, and Student's t-tests assessed accuracy differences. A P value < .05 was considered significant, with a Bonferroni correction applied for multiple comparisons.

Results: The sample consisted of 20 patients (15 females, 75%; 5 males, 25%; mean age 24 ± 11.3 years) evenly divided into BB (n = 10) and BTB (n = 10) guide groups. The BTB guide demonstrated superior vertical accuracy for the upper incisor (mean difference: 0.67 mm, standard deviation = 0.33, P = .02) and the upper left canine (mean difference: 0.11 mm, standard deviation = 0.04, P = .03) when comparing means. However, no significant differences were found in root mean square discrepancies (P > .2) or other measurements (P > .06).

Conclusions and relevance: Both guides achieved acceptable accuracy overall, with the BTB guide showing superior precision for 2 of the 11 landmarks.

{"title":"Accuracy of Two Different Patient-Specific Drill/Cutting Guides for Maxillary Repositioning When Used for Minimally Invasive Bimaxillary Orthognathic Surgery.","authors":"Felix Jose Amarista, Edward Ellis","doi":"10.1016/j.joms.2025.01.001","DOIUrl":"10.1016/j.joms.2025.01.001","url":null,"abstract":"<p><strong>Background: </strong>Minimally invasive orthognathic surgery (MIOS) involves smaller incisions and minimal tissue dissection. Most MIOS is done using interim splints to position the first jaw. The application of patient-specific implants in MIOS is difficult due to the size of traditional cutting/drill guides, which require larger incisions. As a result, MIOS guides were redesigned for this study to fit into smaller incisions.</p><p><strong>Purpose: </strong>The study purpose was to estimate and compare the accuracy of the smaller and redesigned bone-borne (BB) versus bone/tooth-borne (BTB) cutting/drilling guides used in minimally invasive bimaxillary orthognathic surgery.</p><p><strong>Study design, setting, sample: </strong>This retrospective cohort study included consecutive MIOS patients treated by a single surgeon at the University of Texas Health San Antonio from June 2023 to September 2024. It included patients that underwent bimaxillary MIOS with complete preoperative and postoperative cone-beam computed tomographic records. Exclusion criteria included craniofacial syndromes, severe medical comorbidities, or single-jaw surgery.</p><p><strong>Predictor variable: </strong>The primary predictor variable was the type of cutting/drilling guide (BB vs BTB) used to perform maxillary osteotomy.</p><p><strong>Main outcome variable(s): </strong>The primary outcome variable was accuracy, defined as mean linear discrepancy that is closest to 0 mm. Linear discrepancies between planned and actual maxillary movements were measured.</p><p><strong>Covariates: </strong>Demographics and malocclusion type.</p><p><strong>Analyses: </strong>χ<sup>2</sup> tests compared categorical variables, and Student's t-tests assessed accuracy differences. A P value < .05 was considered significant, with a Bonferroni correction applied for multiple comparisons.</p><p><strong>Results: </strong>The sample consisted of 20 patients (15 females, 75%; 5 males, 25%; mean age 24 ± 11.3 years) evenly divided into BB (n = 10) and BTB (n = 10) guide groups. The BTB guide demonstrated superior vertical accuracy for the upper incisor (mean difference: 0.67 mm, standard deviation = 0.33, P = .02) and the upper left canine (mean difference: 0.11 mm, standard deviation = 0.04, P = .03) when comparing means. However, no significant differences were found in root mean square discrepancies (P > .2) or other measurements (P > .06).</p><p><strong>Conclusions and relevance: </strong>Both guides achieved acceptable accuracy overall, with the BTB guide showing superior precision for 2 of the 11 landmarks.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Journal of Oral and Maxillofacial Surgery
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