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February 2026 AAOMS News and Announcements 2026年2月AAOMS新闻和公告
IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-01 DOI: 10.1016/j.joms.2025.11.009
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引用次数: 0
Artificial Intelligence and Statistical Analysis in Oral and Maxillofacial Surgery Research: An Ally, Not a Replacement 人工智能和统计分析在口腔颌面外科研究:盟友,而不是替代品
IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-01 DOI: 10.1016/j.joms.2025.07.019
Lang Liang , Huan Liang MS , Daniel D. Choi DDS, MD , Sung-Kiang Chuang DMD, MD, DMSc
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引用次数: 0
Does Lateral Pterygoid Muscle Reattach After Ramus-Condyle Unit Reconstruction in Temporomandibular Joint Ankylosis Patients? 颞下颌关节强直患者行支髁单元重建后外侧翼状肌能重新附着吗?
IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-01 DOI: 10.1016/j.joms.2025.10.001
Kamalpreet Kaur MDS , Ongkila Bhutia MDS , Smita Manchanda MD , Ashu Seith Bhalla MD , Rahul Yadav MDS , Krushna Bhatt MDS , Ajoy Roychoudhury MDS
<div><h3>Background</h3><div>The removal of ankylotic bone requires detachment of lateral pterygoid muscle (LPM) from the ankylosed condyle. Whether spontaneous reattachment of LPM occurs or not following autogenous ramus-condyle unit (RCU) reconstruction in temporomandibular joint ankylosis (TMJA) is not yet known.</div></div><div><h3>Purpose</h3><div>The study purpose was to measure and compare the incidence of spontaneous LPM reattachment following 2 RCU reconstruction techniques-costochondral graft (CCG) and transport disc distraction osteogenesis (TDDO) and its implications on postoperative jaw motion.</div></div><div><h3>Study design, setting, sample</h3><div>A double-blind randomized clinical trial was implemented. Pediatric TMJA patients aged 3 to 16 years who consented for ankylosis release and RCU reconstruction were included. Patients were excluded if they had diagnosis other than TMJA, had bilateral/recurrent TMJA, underwent RCU reconstruction using modality other than CCG or TDDO, or did not give consent to come for follow-up/participate in this study.</div></div><div><h3>Predictor variable</h3><div>The primary predictor variable was the RCU reconstruction method (CCG or TDDO).</div></div><div><h3>Outcome variable</h3><div>Primary outcome variables included the presence (yes/no) and anatomical site of LPM reattachment. Secondary outcomes were anatomic (reconstituted condyle formed, volume of LPM, temporalis muscle reattachment and its site) and functional (laterotrusion and maximal interincisal opening).</div></div><div><h3>Covariates</h3><div>The covariates included demographics (age, sex) and perioperative (ankylosis classification, etiology, magnetic resonance imaging evaluation time).</div></div><div><h3>Analyses</h3><div>Nonparametric continuous variables were analyzed using the Wilcoxon rank-sum test, categorical variables with the χ<sup>2</sup> test, and within-group comparisons using the signed-rank test. A <em>P</em> value <.05 was considered statistically significant.</div></div><div><h3>Results</h3><div>The study sample had 12 subjects (median age = 11.5 years (interquartile range (IQR) = 4.5); M:F = 7:5). RCU reconstruction was done with CCG (n = 5 (41.7%)) or TDDO (n = 7 (58.3%)). On magnetic resonance imaging evaluation at median 237 days, the LPM (n = 12/12,100%) and temporalis muscles (n = 11/11,100%) showed spontaneous reattachment. Different sites of LPM reattachment were noticed, ie, on reconstituted condyle neck [n = 3 (25%),CCG = 1 (20%),TDDO = 2 (28.6%)], on reconstituted condyle head [n = 4 (33.3%),CCG = 1 (20%),TDDO = 3 (42.9%); no resorption], and on ramal cut surface [n = 5 (41.7%),CCG = 3 (60%),TDDO = 2 (28.6%) (<em>P</em> = .8)], with lower ipsilateral side volume. At 3 years follow-up, an improvement in median maximal interincisal opening (Preoperative = 9.5 mm (IQR = 2.5),Follow-up = 35 mm (IQR = 6), (<em>P</em> = .002)) and laterotrusion (Ipsilateral:Preoperative = 3 mm (IQR = 10),Follow-up = 10 mm (
背景:移除强直性骨需要从强直性髁上剥离外侧翼状肌(LPM)。颞下颌关节强直(TMJA)患者自体支髁单元(RCU)重建后,LPM是否会自发再附着尚不清楚。目的:研究目的是测量和比较2种RCU重建技术-肋软骨移植(CCG)和运输盘牵张成骨(TDDO)后自发性LPM再附着的发生率及其对术后颌骨运动的影响。研究设计、环境、样本:采用双盲随机临床试验。本研究纳入了3 - 16岁同意解除强直和RCU重建的儿童TMJA患者。排除除TMJA以外的诊断,双侧/复发性TMJA,采用CCG或TDDO以外的方式进行RCU重建,或不同意来随访/参与本研究的患者。预测变量:主要预测变量为RCU重建方法(CCG或TDDO)。结果变量:主要结果变量包括LPM再附着的存在(是/否)和解剖位置。次要结果是解剖(重建髁形成,LPM的体积,颞肌再附着及其位置)和功能(侧突和最大切开口)。协变量:协变量包括人口统计学(年龄、性别)和围手术期(强直分类、病因、磁共振成像评估时间)。分析:非参数连续变量采用Wilcoxon秩和检验,分类变量采用χ2检验,组内比较采用符号秩检验。结果:研究样本有12名受试者,年龄中位数= 11.5岁(四分位数间距(IQR) = 4.5);M: f = 7:5)。用CCG (n = 5(41.7%))或TDDO (n = 7(58.3%))重建RCU。在中位237天的磁共振成像评估中,LPM (n = 12/ 12100%)和颞肌(n = 11/ 11100 %)显示自发再附着。LPM再植部位不同,即重建髁颈[n = 3 (25%),CCG = 1 (20%),TDDO = 2(28.6%)],重建髁头[n = 4 (33.3%),CCG = 1 (20%),TDDO = 3 (42.9%)];无吸收],在侧颊切面[n = 5 (41.7%),CCG = 3 (60%),TDDO = 2 (28.6%) (P = 0.8)],同侧体积较小。在3年的随访中,中位最大切牙开口(术前= 9.5 mm (IQR = 2.5),随访= 35 mm (IQR = 6), (P = 0.002)和侧突(同侧:术前= 3 mm (IQR = 10),随访= 10 mm (IQR = 5), (P = .9)有所改善;对侧:术前:0 mm (IQR = 0),随访:2 mm (IQR = 5), (P = 0.01)。结论及意义:LPM可自发再附着,改善侧突。再附着部位在髁突和冠状骨重建中起着重要作用。
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引用次数: 0
Is Patient-Specific Hardware for Orthognathic Surgery More Frequently Removed Than Stock Plates? 在正颌手术中,患者专用的植入物比普通钢板移除的频率更高吗?
IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-01 DOI: 10.1016/j.joms.2025.10.009
Si Kun Wang BS , Michael C. Britt BS , Lisa Nussbaum MS, MBA , Cory M. Resnick DMD, MD , Bonnie L. Padwa DMD, MD , Mark A. Green DDS, MD

Background

Patient-specific implants (PSIs) offer predictability, accuracy, and ease of use, but their removal requirements after orthognathic surgery are unclear. Removing hardware has both a health care cost and negative impact on patients.

Purpose

The purpose of this study was to compare hardware removal between orthognathic fixation with either PSIs or stock plates and identify risk factors associated with removal.

Study design, setting, sample

This retrospective cohort study included patients with skeletal malocclusion who underwent orthognathic surgery with plate fixation between 2008 and 2024 at Boston Children's Hospital. Patients with less than 3 months of follow-up or incomplete records were excluded.

Predictor variable

The primary predictor variable was the type of hardware used (PSI vs stock).

Outcome variable

The primary outcome was time from plate fixation to plate removal.

Covariates

Covariates included age, sex, presence of cleft lip/palate, procedure type and length, ancillary procedures during the same anesthetic, presence of postoperative malocclusion, hardware lifespan, reason for removal, and plate location.

Analyses

Independent samples t tests, tests of medians, χ2 tests, and Fisher exact tests were used to evaluate sample characteristics. Kaplan-Meier analyses and Cox proportional hazards were used to generate hazard ratios. P values of less than .05 were significant.

Results

The sample included 675 subjects with a mean age of 19.40 years (standard deviation (SD) = 3.29) and 47.9% (n = 323) males. Overall, 8.6% (n = 58) required plate removal, and PSIs were removed more frequently than stock plates (12.8% (n = 33) vs 6.0% (n = 25), respectively, P = .002; unadjusted HR = 3.99, 95% confidence interval (CI): (2.30, 6.93), P < .001). After adjusting for procedure type, ancillary procedures, and postoperative malocclusion, PSIs were associated with a risk of plate removal 8.82 (95% confidence interval (CI): (4.27, 18.20), P < .001) times that of the stock group. Procedure type, procedure length, ancillary procedures during the same anesthetic, and postoperative malocclusion were also associated with removal. The most common reasons for removal included a future procedure and infection, with no difference between cohorts.

Conclusions and relevance

PSIs were associated with an increased risk for hardware removal compared to stock plates for subjects who underwent orthognathic surgery. The benefits and risks of PSIs should be weighed and clinical judgment exercised accordingly.
背景:患者特异性种植体(psi)具有可预测性、准确性和易用性,但其在正颌手术后的移除要求尚不清楚。移除硬件不仅会增加医疗成本,还会对患者产生负面影响。目的:本研究的目的是比较正颌内固定与PSIs或钢板内固定之间的内固定拆除,并确定与拆除相关的危险因素。研究设计、背景、样本:这项回顾性队列研究包括2008年至2024年间在波士顿儿童医院接受正颌手术钢板固定的骨骼错颌患者。随访时间少于3个月或记录不完整的患者排除在外。预测变量:主要预测变量是使用的硬件类型(PSI vs库存)。结局变量:主要结局为从钢板固定到取出钢板的时间。协变量:协变量包括年龄、性别、唇裂/腭裂的存在、手术类型和长度、同一麻醉期间的辅助手术、术后错颌的存在、硬体使用寿命、取出原因和钢板位置。分析:采用独立样本t检验、中位数检验、χ2检验和Fisher精确检验评价样本特征。Kaplan-Meier分析和Cox比例风险用于产生风险比。P值小于。0.05有显著性差异。结果:样本包括675名受试者,平均年龄19.40岁(标准差(SD) = 3.29),男性占47.9% (n = 323)。总体而言,8.6% (n = 58)的患者需要取板,而psi的取板频率高于stock plate(分别为12.8% (n = 33)和6.0% (n = 25), P = 0.002;未经调整的HR = 3.99, 95%可信区间(CI): (2.30, 6.93), P < 0.001)。在调整手术类型、辅助手术和术后错牙合后,PSIs与钢板取出风险的相关性是普通组的8.82倍(95%可信区间(CI):(4.27, 18.20), P < 0.001)。手术类型、手术时间、相同麻醉期间的辅助手术和术后错颌畸形也与拔除有关。最常见的切除原因包括未来的手术和感染,在队列之间没有差异。结论和相关性:接受正颌手术的患者,与普通钢板相比,psi与硬体取出的风险增加有关。应权衡psi的益处和风险,并据此进行临床判断。
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引用次数: 0
Idiopathic First Bite Syndrome Associated With Diabetic Autonomic Neuropathy 与糖尿病自主神经病变相关的特发性第一咬综合征。
IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-01 DOI: 10.1016/j.joms.2025.10.018
Tina Tran MD, DDS , Daniel P. Caruso MD, DDS
First bite syndrome (FBS) is a rare pain disorder characterized by sharp parotid pain triggered by the first bite of each meal and diminishing with continued mastication. It is most often reported as a complication of parapharyngeal or sympathetic chain surgery, with an incidence of approximately 6% to 10% in surgical series. Idiopathic cases, in which no prior surgery or local cause is identified, are exceedingly uncommon, with fewer than 10 described in the literature. Several of these involved patients with diabetes mellitus, suggesting a possible role for autonomic neuropathy. We present a 63-year-old woman with poorly controlled type 2 diabetes who developed parotid pain consistent with idiopathic FBS, without any history of head or neck surgery. Imaging was normal, and neurologic testing confirmed diabetic autonomic neuropathy. With reinitiation of insulin and improved glycemic control, symptoms resolved in parallel with hemoglobin A1c reduction. This case highlights a presentation clinically compatible with idiopathic FBS secondary to diabetic autonomic neuropathy and underscores the importance of recognizing systemic contributors to parotid pain, which may resolve with metabolic optimization.
第一口综合征(FBS)是一种罕见的疼痛障碍,其特征是每顿饭的第一口引起尖锐的腮腺疼痛,并随着继续咀嚼而减轻。最常报道为咽旁或交感连锁手术的并发症,在手术系列中发生率约为6%至10%。特发性病例,其中没有事先手术或局部原因确定,是非常罕见的,在文献中描述不到10。其中几例涉及糖尿病患者,提示自主神经病变可能起作用。我们报告了一名63岁的2型糖尿病患者,她患有与特发性FBS一致的腮腺疼痛,没有任何头颈部手术史。影像学检查正常,神经学检查证实糖尿病自主神经病变。随着胰岛素的重新启动和血糖控制的改善,症状在HbA1c降低的同时得到缓解。该病例强调了临床表现与继发于糖尿病自主神经病变的特发性FBS相一致,并强调了识别腮腺疼痛的全身性因素的重要性,这种疼痛可能通过代谢优化来解决。
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引用次数: 0
Compared to Intravenous Injection of Midazolam, Does Intranasal Dexmedetomidine Provide Adequate Sedation for Dentoalveolar Surgery? 与静脉注射咪达唑仑相比,鼻内注射右美托咪定对牙槽手术有足够的镇静作用吗?
IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-28 DOI: 10.1016/j.joms.2026.01.017
Jing-Mei Yang, Yanzheng Liu, Zhanfei Liang, Chao-Jing Lv
<p><strong>Background: </strong>Conscious sedation is crucial for managing anxiety and ensuring safety during dentoalveolar surgery. The efficacy of intranasal dexmedetomidine as a sedative agent in this context remains unclear.</p><p><strong>Purpose: </strong>The purpose was to measure and compare the level of sedation in subjects receiving either intranasal dexmedetomidine or intravenous midazolam.</p><p><strong>Study design, setting, and sample: </strong>A randomized, nonblinded clinical trial was conducted at the People's Liberation Army 63750 Hospital. Patients scheduled for outpatient dentoalveolar surgery between February and April 2024 were screened. Those requiring vasoactive drugs during operation were excluded.</p><p><strong>Predictor variable: </strong>The primary intervention was the esthetic agent, and subjects were randomly assigned to receive either intranasal dexmedetomidine (1.5 μg/kg) or intravenous midazolam (0.07 mg/kg).</p><p><strong>Outcome variable: </strong>The primary outcome was the Observer's Assessment of Alertness/Sedation scale (1 = deep sleep, 5 = fully alert; lower scores indicate deeper sedation). Measurement time points were when sedation was ready, when local anesthetic infiltration started, 5 minutes, 10 minutes, 15 minutes, 20 minutes, and 30 minutes during the intraoperative period, and 30 minutes after the completion of the operation. Secondary outcomes included visual analog scale, hemodynamic parameters, and adverse events.</p><p><strong>Covariates: </strong>The covariates included demographics (age, sex), perioperative variables (procedure type, medications for heart rate or HBP), and operative details (number of teeth, volume of local anesthetic, and surgical time).</p><p><strong>Analyses: </strong>Data were analyzed using independent samples t tests, χ<sup>2</sup> tests, and repeated measures analysis of variance (ANOVA) for the primary outcome. Statistical significance was set at P < .05.</p><p><strong>Results: </strong>The sample was composed of 103 subjects with a mean age of 63.98 ± 16.89 (P = .6) and 43 (42%) were male (P = .5). Observer's Assessment of Alertness/Sedation scores were 2.65 ± 0.481 and 2.30 ± 0.462 for midazolam and dexmedetomidine, respectively (P < .001). Visual analog scale scores were 1.72 ± 1.180 and 1.27 ± 1.163 for midazolam and dexmedetomidine, respectively (P = .037). Systolic pressure was 124.18 ± 8.4341 and 120.65 ± 9.180 for midazolam and dexmedetomidine, respectively (P = .030). Diastolic pressure was 78.30 ± 5.475 and 76.28 ± 4.762 for midazolam and dexmedetomidine, respectively (P = .033); heart rate was 74.98 ± 3.296 and 72.95 ± 5.047 for midazolam and dexmedetomidine, respectively (P = .010). No significant differences were observed in oxygen saturation (P = .069) or adverse reactions (P = .5).</p><p><strong>Conclusions and relevance: </strong>Compared to intravenous injection of midazolam, intranasal dexmedetomidine was statistically significantly associated with s
背景:在牙槽牙手术中,有意识的镇静对于控制焦虑和确保安全至关重要。在这种情况下,鼻内右美托咪定作为镇静剂的疗效尚不清楚。目的:目的是测量和比较接受鼻内右美托咪定或静脉注射咪达唑仑的受试者的镇静水平。研究设计、设置和样本:在解放军63750医院进行了一项随机、非盲法临床试验。对2024年2月至4月间计划进行牙槽牙门诊手术的患者进行筛查。排除术中需要血管活性药物的患者。预测变量:主要干预为美容剂,受试者被随机分配接受右美托咪定(1.5 μg/kg)鼻内注射或咪达唑仑(0.07 mg/kg)静脉注射。结果变量:主要结果为观察者警觉性/镇静评估量表(1 =深度睡眠,5 =完全清醒,分数越低表明镇静程度越深)。测量时间点分别为镇静准备时、局麻开始浸润时、术中5分钟、10分钟、15分钟、20分钟、30分钟、手术结束后30分钟。次要结局包括视觉模拟量表、血流动力学参数和不良事件。协变量:协变量包括人口统计学(年龄、性别)、围手术期变量(手术类型、用于心率或血压的药物)和手术细节(牙齿数量、局麻量和手术时间)。分析:对主要结局采用独立样本t检验、χ2检验和重复测量方差分析(ANOVA)进行数据分析。差异有统计学意义,P < 0.05。结果:样本共103例,平均年龄63.98±16.89 (P = 0.6),男性43例(42%)(P = 0.5)。咪达唑仑和右美托咪定的警觉/镇静评分分别为2.65±0.481和2.30±0.462 (P < 0.001)。咪达唑仑和右美托咪定的视觉模拟量表评分分别为1.72±1.180和1.27±1.163 (P = 0.037)。咪达唑仑组收缩压为124.18±8.4341,右美托咪定组收缩压为120.65±9.180 (P = 0.030)。咪达唑仑和右美托咪定的舒张压分别为78.30±5.475和76.28±4.762 (P = 0.033);咪达唑仑组心率为74.98±3.296,右美托咪定组心率为72.95±5.047 (P = 0.010)。两组血氧饱和度(P = 0.069)和不良反应(P = 0.5)无显著差异。结论及相关性:与静脉注射咪达唑仑相比,鼻内注射右美托咪定具有更好的术中早期镇静和安全性,具有统计学意义。
{"title":"Compared to Intravenous Injection of Midazolam, Does Intranasal Dexmedetomidine Provide Adequate Sedation for Dentoalveolar Surgery?","authors":"Jing-Mei Yang, Yanzheng Liu, Zhanfei Liang, Chao-Jing Lv","doi":"10.1016/j.joms.2026.01.017","DOIUrl":"https://doi.org/10.1016/j.joms.2026.01.017","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Conscious sedation is crucial for managing anxiety and ensuring safety during dentoalveolar surgery. The efficacy of intranasal dexmedetomidine as a sedative agent in this context remains unclear.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;The purpose was to measure and compare the level of sedation in subjects receiving either intranasal dexmedetomidine or intravenous midazolam.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study design, setting, and sample: &lt;/strong&gt;A randomized, nonblinded clinical trial was conducted at the People's Liberation Army 63750 Hospital. Patients scheduled for outpatient dentoalveolar surgery between February and April 2024 were screened. Those requiring vasoactive drugs during operation were excluded.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Predictor variable: &lt;/strong&gt;The primary intervention was the esthetic agent, and subjects were randomly assigned to receive either intranasal dexmedetomidine (1.5 μg/kg) or intravenous midazolam (0.07 mg/kg).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Outcome variable: &lt;/strong&gt;The primary outcome was the Observer's Assessment of Alertness/Sedation scale (1 = deep sleep, 5 = fully alert; lower scores indicate deeper sedation). Measurement time points were when sedation was ready, when local anesthetic infiltration started, 5 minutes, 10 minutes, 15 minutes, 20 minutes, and 30 minutes during the intraoperative period, and 30 minutes after the completion of the operation. Secondary outcomes included visual analog scale, hemodynamic parameters, and adverse events.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Covariates: &lt;/strong&gt;The covariates included demographics (age, sex), perioperative variables (procedure type, medications for heart rate or HBP), and operative details (number of teeth, volume of local anesthetic, and surgical time).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Analyses: &lt;/strong&gt;Data were analyzed using independent samples t tests, χ&lt;sup&gt;2&lt;/sup&gt; tests, and repeated measures analysis of variance (ANOVA) for the primary outcome. Statistical significance was set at P &lt; .05.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The sample was composed of 103 subjects with a mean age of 63.98 ± 16.89 (P = .6) and 43 (42%) were male (P = .5). Observer's Assessment of Alertness/Sedation scores were 2.65 ± 0.481 and 2.30 ± 0.462 for midazolam and dexmedetomidine, respectively (P &lt; .001). Visual analog scale scores were 1.72 ± 1.180 and 1.27 ± 1.163 for midazolam and dexmedetomidine, respectively (P = .037). Systolic pressure was 124.18 ± 8.4341 and 120.65 ± 9.180 for midazolam and dexmedetomidine, respectively (P = .030). Diastolic pressure was 78.30 ± 5.475 and 76.28 ± 4.762 for midazolam and dexmedetomidine, respectively (P = .033); heart rate was 74.98 ± 3.296 and 72.95 ± 5.047 for midazolam and dexmedetomidine, respectively (P = .010). No significant differences were observed in oxygen saturation (P = .069) or adverse reactions (P = .5).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions and relevance: &lt;/strong&gt;Compared to intravenous injection of midazolam, intranasal dexmedetomidine was statistically significantly associated with s","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146197744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Preoperative Botulinum Toxin A on Pain and Opioid Consumption After Bilateral Sagittal Split Osteotomy: A Randomized Clinical Trial. 术前肉毒毒素A对双侧矢状劈裂截骨术后疼痛和阿片类药物消耗的影响:一项随机临床试验。
IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-27 DOI: 10.1016/j.joms.2026.01.014
Kevin E Lung, Jason Adam, Clayton Davis, Matthew Fay, Daanesh Zakai
<p><strong>Background: </strong>Postoperative pain management due to muscular tension and spasm following mandibular advancement surgery can be clinically challenging. Botulinum toxin type A (BoNT-A) has demonstrated analgesic and muscle-relaxant properties in various medical applications, but its role in acute postoperative pain control in orthognathic procedures remains unclear.</p><p><strong>Purpose: </strong>The purpose of this study was to evaluate whether preoperative BoNT-A injections into the temporalis and masseter muscles reduce postoperative pain intensity and muscle spasms in patients undergoing bilateral sagittal split osteotomy (BSSO) for mandibular advancements.</p><p><strong>Study design and sample: </strong>This study was a prospective, randomized, double-blinded, placebo-controlled clinical trial conducted at Kingsway Oral and Maxillofacial Surgery (Edmonton, Canada). The sample was composed of adult subjects presenting for the evaluation and management of mandibular advancement via BSSO between 2021 and 2024. Subjects were excluded if they had prior orthognathic surgery, chronic pain disorders, neuromuscular disease, pregnancy, prior exposure to BoNT-A, or required concomitant orthognathic procedures.</p><p><strong>Predictor variable: </strong>The predictor variable was preoperative intramuscular injection of BoNT-A, and subjects were randomized to receive either BoNT-A or saline placebo.</p><p><strong>Outcome variables: </strong>The primary outcome was postoperative pain intensity measured on a numerical rating scale (0 = no pain, 10 = worst imaginable pain) over 14 days. Secondary outcomes included frequency of self-reported muscle spasms, postoperative opioid and nonopioid analgesic consumption, and patient satisfaction. Preanalgesic pain scores were recorded immediately prior to taking any analgesic medication, and postanalgesic pain scores were recorded 1 hour after as needed (PRN) analgesic administration.</p><p><strong>Covariates: </strong>Covariates included age, sex, and operative duration.</p><p><strong>Analyses: </strong>Between-group comparisons were performed using independent t tests. Daily pain and medication-use trajectories across 14 postoperative days were evaluated using a linear mixed-effects model with fixed effects for group and time. Statistical significance was set at P < .05.</p><p><strong>Results: </strong>Forty subjects met inclusion criteria (mean age 26.7 years; 55% female). Preanalgesic pain scores were lower in the BoNT-A group (1.72 [SD 0.9]) than in the saline group (2.81 [SD 1.1]; P < .05). Postanalgesic pain did not differ significantly between groups. Opioid consumption over 14 days was significantly lower with BoNT-A (4.9 vs 8.9 doses; P = .046). Mixed-effects modeling demonstrated lower pain and opioid use in the BoNT-A group. No significant differences were observed in nonopioid use or muscle spasm frequency.</p><p><strong>Conclusions and relevance: </strong>Preoperative BoNT-A was associa
背景:下颌前移手术后肌肉紧张和痉挛引起的术后疼痛管理在临床上具有挑战性。A型肉毒毒素(BoNT-A)已在各种医学应用中显示出镇痛和肌肉松弛的特性,但其在正颌手术术后急性疼痛控制中的作用尚不清楚。目的:本研究的目的是评估术前向颞肌和咬肌注射BoNT-A是否能减轻双侧矢状劈开截骨术(BSSO)下颌进展患者术后的疼痛强度和肌肉痉挛。研究设计和样本:本研究是一项前瞻性、随机、双盲、安慰剂对照的临床试验,在Kingsway口腔颌面外科(加拿大埃德蒙顿)进行。样本由成人受试者组成,于2021年至2024年间通过BSSO评估和管理下颌前移。如果受试者既往有正颌手术、慢性疼痛障碍、神经肌肉疾病、妊娠、既往接触BoNT-A或需要同时进行正颌手术,则排除受试者。预测变量:预测变量为术前肌肉注射BoNT-A,受试者随机接受BoNT-A或盐水安慰剂。结果变量:主要结果是术后14天内用数值评定量表测量的疼痛强度(0 =无疼痛,10 =可想象的最严重疼痛)。次要结局包括自我报告的肌肉痉挛频率、术后阿片类和非阿片类镇痛药的使用以及患者满意度。在服用任何镇痛药物前立即记录镇痛前疼痛评分,并在按需给药(PRN)后1小时记录镇痛后疼痛评分。协变量:协变量包括年龄、性别、手术时间。分析:采用独立t检验进行组间比较。术后14天的每日疼痛和药物使用轨迹使用线性混合效应模型进行评估,该模型对组和时间具有固定效应。差异有统计学意义,P < 0.05。结果:40例受试者符合纳入标准(平均年龄26.7岁,女性55%)。镇痛前疼痛评分BoNT-A组(1.72 [SD 0.9])低于生理盐水组(2.81 [SD 1.1]; P < 0.05)。各组间镇痛后疼痛无显著差异。BoNT-A组14天内的阿片类药物消耗量显著降低(4.9 vs 8.9剂量;P = 0.046)。混合效应模型显示BoNT-A组疼痛和阿片类药物使用较低。在非阿片类药物使用或肌肉痉挛频率方面没有观察到显著差异。结论和相关性:术前BoNT-A与通过BSSO下颌前移术后镇痛前疼痛减少和术后阿片类药物使用减少相关。虽然时间趋势倾向于BoNT-A,但疼痛、肌肉痉挛和非阿片类药物使用的日常轨迹差异没有统计学意义。这些发现为BoNT-A作为术后疼痛管理的潜在辅助手段提供了初步支持,值得在更大规模、更充分有力的试验中进一步评估。
{"title":"Effect of Preoperative Botulinum Toxin A on Pain and Opioid Consumption After Bilateral Sagittal Split Osteotomy: A Randomized Clinical Trial.","authors":"Kevin E Lung, Jason Adam, Clayton Davis, Matthew Fay, Daanesh Zakai","doi":"10.1016/j.joms.2026.01.014","DOIUrl":"https://doi.org/10.1016/j.joms.2026.01.014","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Postoperative pain management due to muscular tension and spasm following mandibular advancement surgery can be clinically challenging. Botulinum toxin type A (BoNT-A) has demonstrated analgesic and muscle-relaxant properties in various medical applications, but its role in acute postoperative pain control in orthognathic procedures remains unclear.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;The purpose of this study was to evaluate whether preoperative BoNT-A injections into the temporalis and masseter muscles reduce postoperative pain intensity and muscle spasms in patients undergoing bilateral sagittal split osteotomy (BSSO) for mandibular advancements.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study design and sample: &lt;/strong&gt;This study was a prospective, randomized, double-blinded, placebo-controlled clinical trial conducted at Kingsway Oral and Maxillofacial Surgery (Edmonton, Canada). The sample was composed of adult subjects presenting for the evaluation and management of mandibular advancement via BSSO between 2021 and 2024. Subjects were excluded if they had prior orthognathic surgery, chronic pain disorders, neuromuscular disease, pregnancy, prior exposure to BoNT-A, or required concomitant orthognathic procedures.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Predictor variable: &lt;/strong&gt;The predictor variable was preoperative intramuscular injection of BoNT-A, and subjects were randomized to receive either BoNT-A or saline placebo.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Outcome variables: &lt;/strong&gt;The primary outcome was postoperative pain intensity measured on a numerical rating scale (0 = no pain, 10 = worst imaginable pain) over 14 days. Secondary outcomes included frequency of self-reported muscle spasms, postoperative opioid and nonopioid analgesic consumption, and patient satisfaction. Preanalgesic pain scores were recorded immediately prior to taking any analgesic medication, and postanalgesic pain scores were recorded 1 hour after as needed (PRN) analgesic administration.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Covariates: &lt;/strong&gt;Covariates included age, sex, and operative duration.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Analyses: &lt;/strong&gt;Between-group comparisons were performed using independent t tests. Daily pain and medication-use trajectories across 14 postoperative days were evaluated using a linear mixed-effects model with fixed effects for group and time. Statistical significance was set at P &lt; .05.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Forty subjects met inclusion criteria (mean age 26.7 years; 55% female). Preanalgesic pain scores were lower in the BoNT-A group (1.72 [SD 0.9]) than in the saline group (2.81 [SD 1.1]; P &lt; .05). Postanalgesic pain did not differ significantly between groups. Opioid consumption over 14 days was significantly lower with BoNT-A (4.9 vs 8.9 doses; P = .046). Mixed-effects modeling demonstrated lower pain and opioid use in the BoNT-A group. No significant differences were observed in nonopioid use or muscle spasm frequency.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions and relevance: &lt;/strong&gt;Preoperative BoNT-A was associa","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of Facial Fractures Encountered in the Emergency Department Setting in the United States: An Update of Nationwide Estimates. 在美国急诊科环境中遇到的面部骨折的流行病学:全国估计的更新。
IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-22 DOI: 10.1016/j.joms.2026.01.015
Michael D Han, Sofie Vogel, Gloria Ahn, Min Kyeong Lee, Veerasathpurush Allareddy

Background: Facial fractures cause morbidity and involve intense resource use. Over the last two decades, several societal developments such as enactment of the Affordable Care Act and the COVID-19 pandemic occurred that could have potentially impacted facial fracture care.

Purpose: The purpose of this study was to present the newest available nationwide epidemiologic data on facial fractures encountered in hospital-based emergency department (ED) settings in the United States (US), for years 2021 and 2022, and narratively compared to 2007, when the last epidemiologic data were published using the same database source.

Study design, setting, and sample: This was a descriptive retrospective case series of the 2021 and 2022 Nationwide Emergency Department Sample database. All ED visits for the years 2021 and 2022 were included in the study, and those with missing data were excluded from analysis.

Predictor variable: Given the descriptive study nature, there were no predictor variables.

Main outcome variable: The primary outcome variable was the frequency of facial fractures. Secondary outcome variables included fracture site, sociodemographic variables (age, sex, race, and insurance status), and patient- and hospital-related factors (disposition and ED charges in 2022 US dollars).

Covariates: There were no covariates.

Analysis: Descriptive statistics, including weighted frequencies, weighted means, standard error, and 95% CI, were calculated.

Results: Between 2021 and 2022, there were 965,750 facial fracture-related ED visits, representing a 9.5% interval increase over the 2 years and up to 24% increase compared to 2007. Mean age (46.6 years, standard error 0.2; 95% CI 46.4-47.3) and female presentation (37.4%) measurably increased compared to 2007, whereas the uninsured population decreased. Nasal bone (58.1%) was the most commonly involved area, followed by the orbit, maxilla, mandible, and zygoma. Most were routinely discharged from the ED (66.5%), and 23.3% were admitted. Mean ED charge was $12,013 (standard error 247; 95% CI 11,527, 12,498) per encounter, with total charges of $10,794,020,671 for 2021 and 2022.

Conclusions and relevance: Recognizing these significant sociodemographic, patient, and hospital-related changes can guide clinical care and policy-making, especially for targeted resource allocation. The findings can also serve as the basis for follow-up studies using complementary data sources.

背景:面部骨折发病率高,需要大量的资源使用。在过去的二十年里,一些社会发展,如《平价医疗法案》的颁布和COVID-19大流行的发生,可能会影响面部骨折的护理。目的:本研究的目的是介绍2021年和2022年美国医院急诊科(ED)设置中遇到的面部骨折的最新全国流行病学数据,并与2007年进行叙述性比较,2007年最后一次流行病学数据发表时使用相同的数据库来源。研究设计、环境和样本:这是2021年和2022年全国急诊科样本数据库中的描述性回顾性病例系列。所有2021年和2022年的急诊就诊都被纳入研究,数据缺失的患者被排除在分析之外。预测变量:考虑到描述性研究的性质,没有预测变量。主要结局变量:主要结局变量为面部骨折的发生频率。次要结局变量包括骨折部位、社会人口学变量(年龄、性别、种族和保险状况)以及患者和医院相关因素(处置和急诊费用(2022美元))。协变量:没有协变量。分析:计算描述性统计,包括加权频率、加权平均值、标准误差和95% CI。结果:在2021年至2022年期间,有965,750例面部骨折相关的急诊就诊,两年内间隔增加9.5%,与2007年相比增加了24%。与2007年相比,平均年龄(46.6岁,标准误差0.2;95% CI 46.4-47.3)和女性表现(37.4%)明显增加,而未投保人口减少。最常见的受累部位为鼻骨(58.1%),其次为眼眶、上颌骨、下颌骨和颧骨。大多数例行出院(66.5%),23.3%入院。平均每次急诊费用为12013美元(标准误差247;95% CI 11527,12498), 2021年和2022年的总费用为10794,020,671美元。结论和相关性:认识到这些重要的社会人口、患者和医院相关的变化可以指导临床护理和决策,特别是有针对性的资源分配。这些发现也可以作为使用补充数据源的后续研究的基础。
{"title":"Epidemiology of Facial Fractures Encountered in the Emergency Department Setting in the United States: An Update of Nationwide Estimates.","authors":"Michael D Han, Sofie Vogel, Gloria Ahn, Min Kyeong Lee, Veerasathpurush Allareddy","doi":"10.1016/j.joms.2026.01.015","DOIUrl":"https://doi.org/10.1016/j.joms.2026.01.015","url":null,"abstract":"<p><strong>Background: </strong>Facial fractures cause morbidity and involve intense resource use. Over the last two decades, several societal developments such as enactment of the Affordable Care Act and the COVID-19 pandemic occurred that could have potentially impacted facial fracture care.</p><p><strong>Purpose: </strong>The purpose of this study was to present the newest available nationwide epidemiologic data on facial fractures encountered in hospital-based emergency department (ED) settings in the United States (US), for years 2021 and 2022, and narratively compared to 2007, when the last epidemiologic data were published using the same database source.</p><p><strong>Study design, setting, and sample: </strong>This was a descriptive retrospective case series of the 2021 and 2022 Nationwide Emergency Department Sample database. All ED visits for the years 2021 and 2022 were included in the study, and those with missing data were excluded from analysis.</p><p><strong>Predictor variable: </strong>Given the descriptive study nature, there were no predictor variables.</p><p><strong>Main outcome variable: </strong>The primary outcome variable was the frequency of facial fractures. Secondary outcome variables included fracture site, sociodemographic variables (age, sex, race, and insurance status), and patient- and hospital-related factors (disposition and ED charges in 2022 US dollars).</p><p><strong>Covariates: </strong>There were no covariates.</p><p><strong>Analysis: </strong>Descriptive statistics, including weighted frequencies, weighted means, standard error, and 95% CI, were calculated.</p><p><strong>Results: </strong>Between 2021 and 2022, there were 965,750 facial fracture-related ED visits, representing a 9.5% interval increase over the 2 years and up to 24% increase compared to 2007. Mean age (46.6 years, standard error 0.2; 95% CI 46.4-47.3) and female presentation (37.4%) measurably increased compared to 2007, whereas the uninsured population decreased. Nasal bone (58.1%) was the most commonly involved area, followed by the orbit, maxilla, mandible, and zygoma. Most were routinely discharged from the ED (66.5%), and 23.3% were admitted. Mean ED charge was $12,013 (standard error 247; 95% CI 11,527, 12,498) per encounter, with total charges of $10,794,020,671 for 2021 and 2022.</p><p><strong>Conclusions and relevance: </strong>Recognizing these significant sociodemographic, patient, and hospital-related changes can guide clinical care and policy-making, especially for targeted resource allocation. The findings can also serve as the basis for follow-up studies using complementary data sources.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Association Between Body Mass Index and Facial Anthropometric Measurements: A Cross-Sectional Study. 评价身体质量指数与面部人体测量之间的关系:一项横断面研究。
IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-22 DOI: 10.1016/j.joms.2026.01.012
Rishika Chopra, Shruti Gupta, Anita Hooda

Background: There are notable differences in facial morphology between obese individuals and those of normal weight. A person's body mass index (BMI) is a key factor, affecting the thickness of facial soft tissues.

Purpose: This study aims to examine the association between BMI and facial anthropometric measurements.

Study design, setting, and sample: This prospective, observational (cross-sectional) study was conducted among undergraduate dental students at the Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, who were originally from Haryana. Subjects with a history of trauma and congenital or chronic diseases affecting craniofacial morphology, facial surgeries, facial deformities, orthodontic treatment, or systemic diseases such as hypothyroidism/hyperthyroidism or diabetes that could influence BMI were excluded.

Predictor variable: BMI (ratio of body weight to the square of standing height) served as the predictor, and participants were categorized into four groups: underweight (BMI <18.5), normal (BMI = 18.5 to 22.9), overweight (BMI = 23 to 24.9), and obese (BMI ≥25).

Main outcome variable(s): Measurements for 12 facial anthropometric parameters were obtained using a digital vernier caliper.

Covariates: The covariates were sex and age.

Analyses: One-way ANOVA, general linear model, and independent sample t test were utilized for statistical analysis. The significance criterion was P < .01.

Results: Among the 202 subjects included, 137 (67.8%) were female, and 65 (32.2%) were male. Participants ranged in age from 18 to 30 years, with a mean age of 21.59 ± 1.82 years. Statistically significant differences were observed in face width (P < .001), lower facial width (P < .001), nose width (P < .001), and lower third face height (P = .002) across BMI categories. The mean BMI showed a statistically significant difference regarding sex; however, this difference was not significant concerning age (≤20 years vs >20 years). There was a statistically significant relationship between sex and the studied facial anthropometric parameters, except for nose length, face height (middle third), and facial index. Subjects ≤20 years versus >20 years showed a statistically significant difference in outercanthal distance, nose length, and mouth width.

Conclusions and relevance: The study results suggest that BMI is associated with facial anthropometric measurements; therefore, it may be important to adjust anthropometric measures for BMI when planning orthodontic treatment, esthetic surgeries, and facial reconstruction.

背景:肥胖个体与正常体重个体的面部形态存在显著差异。一个人的身体质量指数(BMI)是影响面部软组织厚度的关键因素。目的:本研究旨在探讨BMI与面部人体测量的关系。研究设计、环境和样本:这项前瞻性、观察性(横断面)研究是在罗塔克牙科科学研究生院(PGIDS)的本科牙科学生中进行的,他们来自哈里亚纳邦。排除有创伤史和影响颅面形态的先天性或慢性疾病、面部手术、面部畸形、正畸治疗或全身性疾病(如甲状腺功能减退/甲状腺功能亢进或糖尿病)可能影响BMI的受试者。预测变量:BMI(体重与站立高度的平方之比)作为预测变量,参与者被分为四组:体重不足(BMI)主要结果变量:使用数字游标卡尺测量12个面部人体测量参数。协变量:协变量为性别和年龄。分析:采用单因素方差分析、一般线性模型和独立样本t检验进行统计分析。显著性标准为P < 0.01。结果:纳入的202例受试者中,女性137例(67.8%),男性65例(32.2%)。参与者年龄从18岁到30岁不等,平均年龄21.59±1.82岁。面部宽度(P < .001)、下面部宽度(P < .001)、鼻宽(P < .001)和下三分之一面部高度(P = .002)在BMI分类中存在统计学差异。平均BMI在性别上有统计学上的显著差异;然而,这种差异在年龄上不显著(≤20岁vs .≤20岁)。除鼻长、脸高(中间三分之一)和面部指数外,性别与所研究的面部人体测量参数之间存在统计学显著关系。年龄≤20岁的受试者与年龄≤20岁的受试者在鼻外距离、鼻长、口宽方面差异有统计学意义。结论和相关性:研究结果提示BMI与面部人体测量值相关;因此,在计划正畸治疗、美容手术和面部重建时,调整BMI的人体测量值可能很重要。
{"title":"Evaluation of the Association Between Body Mass Index and Facial Anthropometric Measurements: A Cross-Sectional Study.","authors":"Rishika Chopra, Shruti Gupta, Anita Hooda","doi":"10.1016/j.joms.2026.01.012","DOIUrl":"https://doi.org/10.1016/j.joms.2026.01.012","url":null,"abstract":"<p><strong>Background: </strong>There are notable differences in facial morphology between obese individuals and those of normal weight. A person's body mass index (BMI) is a key factor, affecting the thickness of facial soft tissues.</p><p><strong>Purpose: </strong>This study aims to examine the association between BMI and facial anthropometric measurements.</p><p><strong>Study design, setting, and sample: </strong>This prospective, observational (cross-sectional) study was conducted among undergraduate dental students at the Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, who were originally from Haryana. Subjects with a history of trauma and congenital or chronic diseases affecting craniofacial morphology, facial surgeries, facial deformities, orthodontic treatment, or systemic diseases such as hypothyroidism/hyperthyroidism or diabetes that could influence BMI were excluded.</p><p><strong>Predictor variable: </strong>BMI (ratio of body weight to the square of standing height) served as the predictor, and participants were categorized into four groups: underweight (BMI <18.5), normal (BMI = 18.5 to 22.9), overweight (BMI = 23 to 24.9), and obese (BMI ≥25).</p><p><strong>Main outcome variable(s): </strong>Measurements for 12 facial anthropometric parameters were obtained using a digital vernier caliper.</p><p><strong>Covariates: </strong>The covariates were sex and age.</p><p><strong>Analyses: </strong>One-way ANOVA, general linear model, and independent sample t test were utilized for statistical analysis. The significance criterion was P < .01.</p><p><strong>Results: </strong>Among the 202 subjects included, 137 (67.8%) were female, and 65 (32.2%) were male. Participants ranged in age from 18 to 30 years, with a mean age of 21.59 ± 1.82 years. Statistically significant differences were observed in face width (P < .001), lower facial width (P < .001), nose width (P < .001), and lower third face height (P = .002) across BMI categories. The mean BMI showed a statistically significant difference regarding sex; however, this difference was not significant concerning age (≤20 years vs >20 years). There was a statistically significant relationship between sex and the studied facial anthropometric parameters, except for nose length, face height (middle third), and facial index. Subjects ≤20 years versus >20 years showed a statistically significant difference in outercanthal distance, nose length, and mouth width.</p><p><strong>Conclusions and relevance: </strong>The study results suggest that BMI is associated with facial anthropometric measurements; therefore, it may be important to adjust anthropometric measures for BMI when planning orthodontic treatment, esthetic surgeries, and facial reconstruction.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Economic Burden of Inpatient Odontogenic Infections in the United States. 美国住院患者牙源性感染的经济负担。
IF 2.6 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-22 DOI: 10.1016/j.joms.2026.01.013
Tim T Wang, Lang Liang, Nicholas Wilken, Gary Warburton, Zachary S Peacock, John Caccamese, Cameron Lee

Background: Odontogenic infections represent a significant yet preventable cause of health care expenditure in the United States. However, their economic burden is not well defined.

Purpose: The purpose of this study was to estimate the per-admission hospital costs of managing odontogenic infections and identify factors associated with increased cost.

Study design, setting, and sample: This was a retrospective cohort study using the National Inpatient Sample database from years 2017 to 2019. Adults admitted for management of an odontogenic infection based on ICD-10 coding were included. Patients under 18 years or missing outcomes data were excluded.

Predictor variable: The predictors were variables categorized into demographic (age, sex), clinical (Charlson comorbidity index), procedural (incision and drainage), and hospital characteristics (teaching status) groups.

Main outcome variable: The outcome was economic burden measured as the total hospital cost of admission, derived by applying hospital-specific cost to charge ratios to reported charges and adjusting for inflation to 2019 dollars.

Covariates: None.

Analyses: Survey-weighted descriptive, bivariate, and generalized linear model statistics were used to evaluate the association between cost and study variables. Costs were log-transformed in analyses to address for right skew. Effects are reported as cost ratios (CRs) or the multiplicative change in expected cost versus the reference group; for continuous variables, the CR reflects the change per one-unit increase.

Results: There were 52,250 weighted admissions (∼17,417/year) with a mean age of 41.8 ± 20.5 years and 24,655 males (47.2%). The mean and median costs per admission were $8,162 ± 10,282 and $5,863 [IQR $3,744 to 9,013], respectively. The total annual national cost was $142 million. In adjusted analysis, higher costs were primarily driven by disease severity with airway intervention (CR 3.04, 95% CI 2.83 to 3.27), mediastinitis (CR 2.50, 95% CI 1.73 to 3.62), necrotizing fasciitis (CR 1.79, 95% CI 1.34 to 2.38), sepsis (CR 1.30, 95% CI 1.25 to 1.35), and incision and drainage (CR 1.20, 95% CI 1.17 to 1.24) having the highest CRs (all P < .001). Time to drainage in days (CR 1.13, 95% CI 1.11 to 1.15) was the only modifiable driver.

Conclusions and relevance: Inpatient management of odontogenic infections imposes substantial national costs, driven largely by markers of disease severity.

背景:牙源性感染是美国医疗保健支出的一个重要但可预防的原因。然而,他们的经济负担并没有得到很好的界定。目的:本研究的目的是估计处理牙源性感染的入院前医院成本,并确定与成本增加相关的因素。研究设计、环境和样本:这是一项回顾性队列研究,使用了2017年至2019年的国家住院患者样本数据库。纳入了根据ICD-10编码入院治疗牙源性感染的成年人。排除了18岁以下的患者或缺少结局数据的患者。预测变量:预测变量分为人口学组(年龄、性别)、临床组(Charlson合并症指数)、手术组(切口和引流)和医院特征组(教学状况)。主要结局变量:结果是经济负担,以住院总成本衡量,通过将医院特定成本与报告收费的比率应用并根据通货膨胀调整为2019年美元计算得出。共:没有。分析:使用调查加权描述性、双变量和广义线性模型统计来评估成本与研究变量之间的关系。在分析中对成本进行对数变换,以解决右偏问题。效果报告为成本比(CRs)或预期成本与参照组的乘积变化;对于连续变量,CR反映每增加一个单位的变化。结果:52,250例加权入院(~ 17,417例/年),平均年龄41.8±20.5岁,男性24,655例(47.2%)。每次入院的平均费用和中位数分别为8,162±10,282美元和5,863美元[IQR $3,744至9,013]。全国每年的总费用为1.42亿美元。在调整分析中,较高的成本主要是由疾病严重程度所致,气道干预(CR 3.04, 95% CI 2.83至3.27)、纵膈炎(CR 2.50, 95% CI 1.73至3.62)、坏死性筋膜炎(CR 1.79, 95% CI 1.34至2.38)、败血症(CR 1.30, 95% CI 1.25至1.35)和切口引流(CR 1.20, 95% CI 1.17至1.24)的CR最高(均P < 0.001)。引流时间(CR = 1.13, 95% CI = 1.11 ~ 1.15)是唯一可改变的驱动因素。结论和相关性:牙源性感染的住院治疗在很大程度上由疾病严重程度的标志物驱动,造成了巨大的国家成本。
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引用次数: 0
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Journal of Oral and Maxillofacial Surgery
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