Journal of Oral and Maxillofacial Surgery最新文献

{"title":"RE: Aromatherapy on Anxiety, Pain, and Quality of Life Following Surgery of Mandibular Third Molars: A Randomized, Double-Blind Clinical Trial","authors":"Deepak Bangera MD (Naturopathy), Deenadayalan Boopalan MD (Naturopathy), N.V. Gnana Deep Tatavarti MD (Naturopathy), Raghavendra Rao Mohan PhD (Yoga and Life Sciences)","doi":"10.1016/j.joms.2025.07.017","DOIUrl":"10.1016/j.joms.2025.07.017","url":null,"abstract":"","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 1","pages":"Page 12"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145860743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Reiki Therapy ReducePreoperative Anxiety and Postoperative Pain in Third Molar Surgery? A Randomized Controlled Trial","authors":"Meltem Ozden Yuce PhD ,&nbsp;Birant Simsek PhD ,&nbsp;Omer Faruk Dadas PhD ,&nbsp;Candan Efeoglu PhD","doi":"10.1016/j.joms.2025.09.003","DOIUrl":"10.1016/j.joms.2025.09.003","url":null,"abstract":"<div><h3>Background</h3><div>Preoperative anxiety in patients undergoing third molar extraction can influence pain perception. Limited evidence suggests Reiki therapy may help manage anxiety and pain, but its effectiveness in dentistry is unclear.</div></div><div><h3>Purpose</h3><div>This study evaluated whether Reiki therapy reduces preoperative anxiety and postoperative pain in third molar surgery.</div></div><div><h3>Study Design</h3><div>A single-blind randomized controlled trial was conducted at the Ege University Faculty of Dentistry (İzmir, Türkiye) between March 2021 and February 2023. Participants were 18 to 45 years old, in good general health, with mandibular Class II-B impaction (Pell and Gregory classification), and no prior third molar extraction or Reiki therapy. Exclusion criteria included systemic disease, pregnancy, acute infection, pathological lesions, use of anxiolytic/antidepressant drugs, and inability to provide consent.</div></div><div><h3>Predictor Variable</h3><div>The predictor variable was the type of preoperative intervention. Participants were randomly assigned to 1 of 3 conditions: Reiki therapy, sham Reiki, or no intervention.</div></div><div><h3>Main Outcome Variable</h3><div>Primary outcomes were preoperative anxiety [State-Trait Anxiety Inventory I, State-Trait Anxiety Inventory II, and Beck Anxiety Inventory] and postoperative pain [visual analog scale over 7 days]. Analgesic use during the first postoperative week was recorded.</div></div><div><h3>Covariates</h3><div>Covariates included sex, baseline anxiety scores, surgery duration, and the quantity/timing of additional analgesic intake in the first postoperative week.</div></div><div><h3>Analyses</h3><div>Nonparametric tests were used with R software. The Brunner–Langer model assessed group differences in anxiety, pain, and analgesic use. Kruskal–Wallis and Wilcoxon signed-rank tests compared intergroup and intragroup outcomes (<em>P</em> &lt; .05 considered significant).</div></div><div><h3>Results</h3><div>The sample included 180 participants (mean age 27.4 ± 6.1 years). Randomization resulted in an equal distribution of males and females across the groups. Reiki therapy did not significantly reduce preoperative anxiety (mean State-Trait Anxiety Inventory I: 36.6 ± 10.0; <em>P</em> = .079) compared with sham Reiki (40.1 ± 10.1) and no intervention (40.8 ± 10.8). Postoperative pain scores were significantly lower in the Reiki group (mean 2.7 ± 1.8) compared with sham Reiki (3.0 ± 1.7) and no intervention (3.5 ± 1.9) (<em>P</em> = .045).</div></div><div><h3>Conclusion and Relevance</h3><div>Reiki therapy did not reduce preoperative anxiety but was associated with lower postoperative pain. Further trials are warranted to clarify its role in oral and maxillofacial surgery.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 1","pages":"Pages 101-108"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Evoked Electromyography Detect Postoperative Facial Nerve Recovery Earlier Than Grading Scales Following Temporomandibular Joint Ankylosis Surgery?","authors":"Abiskar Basnet MDS ,&nbsp;Saurabh Simre MDS ,&nbsp;Ashi Chug MDS, PhD ,&nbsp;Prem Kumar Rathod MDS ,&nbsp;Aparna Mahajan BDS ,&nbsp;Poorvi Kulshrestha MD","doi":"10.1016/j.joms.2025.09.018","DOIUrl":"10.1016/j.joms.2025.09.018","url":null,"abstract":"<div><h3>Background</h3><div>Facial nerve (FN) dysfunction is a potential postoperative complication of managing temporomandibular joint ankylosis (TMJa).</div></div><div><h3>Purpose</h3><div>The purpose of this study was to determine whether evoked electromyography (EEMG) detects postoperative FN function (FNF) recovery earlier than House-Brackmann scale (HBS) and Sunnybrook scale (SBS) following TMJa surgery.</div></div><div><h3>Study Design, Setting, Sample</h3><div>A prospective, single tertiary-care center cohort study was conducted at All India Institute of Medical Sciences, Rishikesh from October 2022 to April 2024. Patients with unilateral TMJa aged above 12 years were included. Exclusion criteria were previous surgery of parotid/temporomandibular joint, preexisting FN palsy, neuromuscular disorders, syndromic patients.</div></div><div><h3>Predictor Variable</h3><div>The primary predictor variable was FNF recovery monitoring tool (EEMG vs HBS vs SBS).</div></div><div><h3>Main Outcome Variables</h3><div>The primary outcome variable was FNF recovery time. This was recorded postoperatively at defined time-points (1 week-T1, 1 month-T2, 3 months-T3, 6 months-T4).</div></div><div><h3>Covariates</h3><div>Covariates included age, sex, and operative time.</div></div><div><h3>Analysis</h3><div>Data were analyzed using SPSSversion20. Frequencies (percentages) were compared using χ² and Fisher's exact tests. Kaplan–Meier survival analysis and Cox-regression were used to assess recovery hazards, adjusting for covariates with level of statistical significance set at <em>P</em> &lt; .05.</div></div><div><h3>Results</h3><div>The sample composed of 65 subjects of unilateral TMJa undergoing surgery. The mean age was 20.13 ± 7.58 years and included 27 females (42%) and 38 males (58%). Iatrogenic FN injury occurred in 15 (23%) cases. The median time to detect FNF recovery by EEMG was 6 weeks (interquartile range [IQR] 3 to 12) versus HBS 15 weeks [IQR 11 to 19] versus SBS 18 weeks [IQR 13 to 20] which was statistically significant favoring EEMG (95% CI, <em>P</em> &lt; .05). Complete recovery of FNF was noted in all 15 cases. The chance of early detection of recovery by EEMG was 32% greater than with HBS and SBS (hazard ratio: 1.32, 95% CI, 1.02 to 1.72, <em>P</em> &lt; .05).</div></div><div><h3>Conclusion and Relevance</h3><div>EEMG detects FNF recovery earlier than grading scales, and is a valid electrodiagnostic test for postoperative monitoring.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 1","pages":"Pages 18-24"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145370267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AAOMS Author Disclosure forms","authors":"","doi":"10.1016/S0278-2391(25)00886-9","DOIUrl":"10.1016/S0278-2391(25)00886-9","url":null,"abstract":"","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 1","pages":"Pages A5-A7"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145860218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"January 2026 AAOMS News and Announcements","authors":"","doi":"10.1016/j.joms.2025.10.005","DOIUrl":"10.1016/j.joms.2025.10.005","url":null,"abstract":"","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 1","pages":"Pages 141-144"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145860222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Federal Student Loan Changes Uniquely Impact 6-Year Oral and Maxillofacial Surgery Residents","authors":"Clark D. Morgan ,&nbsp;Samat T. Borbiev ,&nbsp;Zachary S. Peacock DMD, MD","doi":"10.1016/j.joms.2025.07.016","DOIUrl":"10.1016/j.joms.2025.07.016","url":null,"abstract":"","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 1","pages":"Pages 9-10"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145860742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of Recurrence and Oncologic Outcomes After Maxillectomy: Does Reconstructive Modality Matter?","authors":"Cameron Lee DMD, MD ,&nbsp;Salim Abdul Wasay DDS ,&nbsp;Glyndwr Jenkins BChD, MBBS ,&nbsp;Kelly Moyer MD ,&nbsp;Kyle Hatten MD ,&nbsp;Jeffrey S. Wolf MD ,&nbsp;Rodney Taylor MD, MSPH ,&nbsp;Joshua Lubek DDS, MD ,&nbsp;Donita Dyalram DDS, MD","doi":"10.1016/j.joms.2025.09.021","DOIUrl":"10.1016/j.joms.2025.09.021","url":null,"abstract":"<div><h3>Background</h3><div>Reconstruction following maxillectomy for oral cavity malignancies is essential for restoring form and function. Obturator reconstruction facilitates direct visualization of the surgical bed, whereas flap-based reconstructions may obscure sites of potential recurrence. This has raised concern that reconstructive modality could influence the timeliness of recurrence detection, and subsequently, oncologic outcomes.</div></div><div><h3>Purpose</h3><div>The purpose of this study was to measure the association between reconstructive modality and time to detection of local recurrence and survival outcomes.</div></div><div><h3>Study design, setting sample</h3><div>This was a retrospective cohort study of all patients undergoing maxillectomy for an oral cavity malignancy at the University of Maryland between 2016 and 2024. Patients previously undergoing maxillectomy were excluded.</div></div><div><h3>Predictor variable</h3><div>The predictor was reconstructive modality: obturator versus native tissue reconstruction (local, regional, or free flap).</div></div><div><h3>Main outcome variable</h3><div>The primary outcome was local disease-free survival. Secondary outcomes included overall survival, method of recurrence detection (clinical vs radiographic), and resectability of recurrence.</div></div><div><h3>Covariates</h3><div>Covariates were categorized into demographic (age, sex), perioperative (Brown classification), and pathologic (margin status, tumor stage).</div></div><div><h3>Analyses</h3><div>Descriptive statistics were computed for study variables. Associations between study covariates and time to local recurrence were evaluated using bivariate Cox proportional hazards models.</div></div><div><h3>Results</h3><div>The cohort was composed of 154 subjects with a mean age of 66.5 ± 14.9 years and 90 were male (58.4%). Fifty subjects (32.5%) underwent obturator reconstruction and 104 (67.5%) underwent reconstruction with native tissue (75% free flap). Reconstructive modality was not associated with local disease-free survival (<em>P</em> = .9), method of detection (<em>P</em> = .4), or overall survival (<em>P</em> = .3). Local recurrence occurred in 41 subjects (26.6%), with 14 (34.1%) in the obturator group compared to 27 (65.9%) in native tissue (<em>P</em> = .7). The median time to local recurrence was 7.7 months (interquartile range 26.2 months). Most recurrences (75.6%) were detected clinically. Subgroup analysis of Brown 2 defects confirmed the similar findings.</div></div><div><h3>Conclusions and relevance</h3><div>Reconstructive modality was not associated with delayed detection of local recurrence or worse survival outcomes following maxillectomy for oral cavity malignancies.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 1","pages":"Pages 115-126"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145459092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Dexmedetomidine Affect Opioid Consumption Following Orthognathic Surgery?","authors":"Allen F. Champion DDS ,&nbsp;Jung-me Lee BS ,&nbsp;Daniel Taub DDS, MD ,&nbsp;Yu Jin Lee DMD","doi":"10.1016/j.joms.2025.08.015","DOIUrl":"10.1016/j.joms.2025.08.015","url":null,"abstract":"<div><h3>Background</h3><div>Despite its purported analgesic effects, controversy exists regarding dexmedetomidine's efficacy as an opioid-sparing anesthetic adjunct.</div></div><div><h3>Purpose</h3><div>The purpose of this study is to measure the association between dexmedetomidine (DEX) administration during orthognathic surgery and postoperative opioid consumption.</div></div><div><h3>Study design, sample, and setting</h3><div>A single-blind randomized prospective cohort study was implemented. Patients consenting for orthognathic surgery at Thomas Jefferson University from January 2022 to October 2024 were screened. American Society of Anesthesiologists physical status I to III individuals aged ≥14 years were included. Exclusion criteria were revision surgery, recreational drug use, opioid prescription within 2 years, and chronic pain.</div></div><div><h3>Predictor variable</h3><div>The predictor variable was anesthetic adjunct. Subjects were randomized to receive DEX or no DEX (control).</div></div><div><h3>Main outcome variables</h3><div>The primary outcome variable was 24-hour postoperative opioid consumption, which was calculated as morphine milligram equivalents (MME). Postoperative pain was assessed using a visual analog scale (VAS) at 6 hours and upon patient-controlled analgesia (PCA) discontinuation at 7:00 <span>am</span> the following day (VASPCA). The ratio of PCA that attempts to bolus deliveries was calculated.</div></div><div><h3>Covariates</h3><div>Covariates included age, sex, body mass index (BMI), and operative duration.</div></div><div><h3>Analyses</h3><div>Descriptive statistics were calculated. Shapiro-Wilk test was used to assess sample normality. Relationships between continuous variables and DEX were studied using <em>t</em> test or Wilcoxon rank-sum test; χ² test was used for the categorical covariate. Significance was <em>P</em> &lt; .05.</div></div><div><h3>Results</h3><div>Of 66 enrollees, 50 (75.8%) subjects completed the trial (25 DEX, 25 no DEX). The mean (SD) ages for the no DEX and DEX group cohorts were 35.9 (13.5) and 41.3 (13.6), respectively (<em>P</em> = .2). There were no statistically significant differences in the distribution of covariates between the 2 study groups. Median (interquartile range (IQR)) morphine milligram equivalents consumption was 16.4 (15.4) and 14.8 (12.4) for no DEX and DEX groups, respectively (<em>P</em> = .9). No difference in pain scores was observed at 6 hours (<em>P</em> = .1). Median (interquartile range) VASPCA scores were 5(1) and 4(2) for no DEX and DEX cohorts, respectively (<em>P</em> &lt; .01). Median ratios of PCA that attempts to boluses administered (1.23) were identical between cohorts (<em>P</em> = .9).</div></div><div><h3>Conclusions and relevance</h3><div>The findings suggest that opioid consumption following orthognathic surgery was not associated with dexmedetomidine administration.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 1","pages":"Pages 13-17"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rates and Determinants of Prosthodontic Rehabilitation After Segmental Jaw Surgery","authors":"Amal Idrissi Janati DMD, MSc, PhD ,&nbsp;Ameena Nizar Beema BDS, MSc ,&nbsp;Jordan Gigliotti DMD, MD, CM ,&nbsp;Nicholas Makhoul DMD, MD ,&nbsp;Michel El-Hakim DMD, MD, MSc ,&nbsp;Nour Karra DMD","doi":"10.1016/j.joms.2025.09.008","DOIUrl":"10.1016/j.joms.2025.09.008","url":null,"abstract":"<div><h3>Background</h3><div>Management of maxillofacial pathologies often requires ablative surgeries of the jaw which may include the tooth-bearing segment resulting in loss of oral function. Advances in maxillomandibular reconstruction with vascularized free flaps (VFFs) and dental implants have enabled prosthodontic rehabilitation (PR) in most patients. However, the impact of these advancements on rates and barriers of PR remains unclear.</div></div><div><h3>Purpose</h3><div>The purpose of this study was to estimate the rate of PR and identify risk factors associated with failure to achieve PR.</div></div><div><h3>Study Design, Setting, Sample</h3><div>This 7-year retrospective cohort study was conducted at the Montreal General Hospital and included patients aged ≥15 years who underwent vascularized free flap reconstruction following jaw segmental resection between 2015 and 2021.</div></div><div><h3>Predictor Variable</h3><div>Predictor variables included age, sex, smoking, clinical diagnosis, adjuvant radiotherapy, flap type, and anterior tooth loss.</div></div><div><h3>Main Outcome Variable(s)</h3><div>The primary outcome is time to PR and secondary outcomes were PR status (not performed vs performed) and PR type (conventional vs implant-supported) respectively.</div></div><div><h3>Covariates</h3><div>NA.</div></div><div><h3>Analyses</h3><div>Descriptive statistics, comparison tests, Kaplan–Meier analysis, and univariate and multivariate Cox and logistic regression analyses were conducted (<em>P</em> &lt; .05).</div></div><div><h3>Results</h3><div>The study included 184 subjects with a mean age of 58 years (SD = 17), and 52% (n = 95) were men. The median follow-up was 20 months (interquartile range = 32). Malignancy was the most common diagnosis leading to surgery (n = 106; 58%), followed by benign tumors (n = 46; 25%). Cumulative proportion of PR was 41% (n = 76), including 19.5% (n = 36) of implant-supported prostheses. Median time to start PR was 44 months (95% CI: 30 to 78) and was significantly delayed in men, ever smokers, cancer patients, and those who received radiotherapy. In multivariate analysis, radiotherapy was the main predictor of failure to receive PR overall (<em>P</em> = .014) and implant-supported PR specifically (<em>P</em> = .025).</div></div><div><h3>Conclusion and Relevance</h3><div>Many patients with dental morbidity after segmental jaw surgery, especially cancer patients requiring radiotherapy, did not receive PR, and even fewer received implant-supported prostheses, highlighting the need for preradiotherapy solutions.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"84 1","pages":"Pages 127-137"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Kindred Reference Form: A New Paradigm for Assessing Facial Morphology in Patients With Deformities.","authors":"Yasmine Soubra, Rohan Dharia, Daeseung Kim, Jaime Gateno","doi":"10.1016/j.joms.2025.12.015","DOIUrl":"10.1016/j.joms.2025.12.015","url":null,"abstract":"<p><p>Normative reference models are essential for assessing facial form, yet existing databases, stratified by ethnicity, age, and sex, have significant limitations, including incompleteness and lack of applicability for mixed-heritage patients. We propose a new paradigm, the Kindred Reference Form, which derives personalized reference morphology from a patient's nondeformed relatives. This framework provides an individualized normative standard overcoming the limitations of population datasets and proposing a new direction for patient-specific surgical planning in facial deformities.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145959778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}