Pub Date : 2016-01-01DOI: 10.4103/2348-3113.159100
Paweł Dutkiewicz, Shashank S Kraleti, D. Jarrett
To describe a patient who presented to a family medicine clinic with symptoms typical for cholecystitis, but eventually was diagnosed with omental infarction. A 37-year-old Caucasian man reported with right upper quadrant pain suspicious for cholecystitis. In light of negative abdominal ultrasound, computed tomography scan was performed, and omental infarction was identified. The patient was treated conservatively with a good outcome. Omental infarction is rarely described in medical literature, and it is often missed or misdiagnosed. There are increasing numbers of reports that describe omental infarction being diagnosed as various types of acute abdomen. With increased utilization of advanced imaging, omental infarction is being found to be responsible for presentations of the acute abdomen that were misdiagnosed. Proper diagnosis prevents invasive mismanagement and an unnecessarily prolonged hospital stay.
{"title":"Omental infarction presenting as abdominal pain typical for cholecystitis","authors":"Paweł Dutkiewicz, Shashank S Kraleti, D. Jarrett","doi":"10.4103/2348-3113.159100","DOIUrl":"https://doi.org/10.4103/2348-3113.159100","url":null,"abstract":"To describe a patient who presented to a family medicine clinic with symptoms typical for cholecystitis, but eventually was diagnosed with omental infarction. A 37-year-old Caucasian man reported with right upper quadrant pain suspicious for cholecystitis. In light of negative abdominal ultrasound, computed tomography scan was performed, and omental infarction was identified. The patient was treated conservatively with a good outcome. Omental infarction is rarely described in medical literature, and it is often missed or misdiagnosed. There are increasing numbers of reports that describe omental infarction being diagnosed as various types of acute abdomen. With increased utilization of advanced imaging, omental infarction is being found to be responsible for presentations of the acute abdomen that were misdiagnosed. Proper diagnosis prevents invasive mismanagement and an unnecessarily prolonged hospital stay.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128247017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.4103/2348-3113.159102
J. Pandiaraja, S. Viswanathan
Thyroid carcinoma with metastatic intracranial involvement is very rare. Intracranial metastases occur in <1% of all cases. Even in thyroid carcinoma medullary carcinoma with intracranial metastasis is extremely rare. This is a case report of 58-year-old male presenting with scalp swelling over the left fronto parietal region, which was diagnosed as medullary carcinoma thyroid with intracranial metastases. This case presented because of it rarity of presentation.
{"title":"Medullary carcinoma thyroid with intracranial metastasis","authors":"J. Pandiaraja, S. Viswanathan","doi":"10.4103/2348-3113.159102","DOIUrl":"https://doi.org/10.4103/2348-3113.159102","url":null,"abstract":"Thyroid carcinoma with metastatic intracranial involvement is very rare. Intracranial metastases occur in <1% of all cases. Even in thyroid carcinoma medullary carcinoma with intracranial metastasis is extremely rare. This is a case report of 58-year-old male presenting with scalp swelling over the left fronto parietal region, which was diagnosed as medullary carcinoma thyroid with intracranial metastases. This case presented because of it rarity of presentation.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123125275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.4103/2348-3113.172526
P. Suresh, Vishnupriya Mathivanan, J. Minal, R. Karthick, H. B. Sridevi, R. Archanadevi
Introduction: Fine needle aspiration cytology (FNAC) of salivary glands is one of the most commonly done first line investigations in the head and neck region. Objectives: To study the cytological features of various salivary gland lesions and to correlate with histopathological diagnosis wherever possible. Materials and Methods: All the FNAC slides of salivary gland lesions received at cytology lab of a tertiary hospital for a period of 3 years that is, from January 2011 to December 2013 were reviewed retrospectively. Histopathological correlation was done for cases wherever available. Results: During the study period salivary gland FNAC was done for 100 cases. Among them, 51 (51%) were reported as nonneoplastic and 49 as neoplastic (49%). Histopathological correlation was available in 18 cases (18%). The accuracy of salivary gland cytology is 77.7% (14/18 cases). The mean age of presentation of all the salivary gland lesions ranged from 12 years to 92 years with the mean age being 47.7 years. The male:female ratio was 1.5:1. Parotid gland was involved in 74 cases and submandibular gland in 26 cases. Bilateral involvement was noted in 1 case (1%). Conclusion: Being a minimally invasive procedure, FNA of salivary glands continues to be an important diagnostic tool in the preoperative diagnosis of salivary gland lesions in spite of few pitfalls in diagnosing due to cytomorphological overlapping.
{"title":"Fine needle aspiration cytology of salivary gland lesions: Our experience","authors":"P. Suresh, Vishnupriya Mathivanan, J. Minal, R. Karthick, H. B. Sridevi, R. Archanadevi","doi":"10.4103/2348-3113.172526","DOIUrl":"https://doi.org/10.4103/2348-3113.172526","url":null,"abstract":"Introduction: Fine needle aspiration cytology (FNAC) of salivary glands is one of the most commonly done first line investigations in the head and neck region. Objectives: To study the cytological features of various salivary gland lesions and to correlate with histopathological diagnosis wherever possible. Materials and Methods: All the FNAC slides of salivary gland lesions received at cytology lab of a tertiary hospital for a period of 3 years that is, from January 2011 to December 2013 were reviewed retrospectively. Histopathological correlation was done for cases wherever available. Results: During the study period salivary gland FNAC was done for 100 cases. Among them, 51 (51%) were reported as nonneoplastic and 49 as neoplastic (49%). Histopathological correlation was available in 18 cases (18%). The accuracy of salivary gland cytology is 77.7% (14/18 cases). The mean age of presentation of all the salivary gland lesions ranged from 12 years to 92 years with the mean age being 47.7 years. The male:female ratio was 1.5:1. Parotid gland was involved in 74 cases and submandibular gland in 26 cases. Bilateral involvement was noted in 1 case (1%). Conclusion: Being a minimally invasive procedure, FNA of salivary glands continues to be an important diagnostic tool in the preoperative diagnosis of salivary gland lesions in spite of few pitfalls in diagnosing due to cytomorphological overlapping.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127272991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-01DOI: 10.4103/2348-3113.152326
N. Sahni, A. Mandal, N. Maheshwari
Hypertriglyceridemia is an important yet often missed cause of acute pancreatitis. The diagnostic dilemma and no specific guidelines for management of this condition further add to difficulty in treating a patient with hypertriglyceridemia induced acute pancreatitis. We present a thirty five year old, diabetic male patient with hypertriglyceridemia induced pancreatitis, enumerating the difficulties in diagnosis and treatment of our patient. A brief review of literature summarizes the various modalities of treatment proposed.
{"title":"Hypertriglyceridemia-induced acute pancreatitis: Yet to be explored","authors":"N. Sahni, A. Mandal, N. Maheshwari","doi":"10.4103/2348-3113.152326","DOIUrl":"https://doi.org/10.4103/2348-3113.152326","url":null,"abstract":"Hypertriglyceridemia is an important yet often missed cause of acute pancreatitis. The diagnostic dilemma and no specific guidelines for management of this condition further add to difficulty in treating a patient with hypertriglyceridemia induced acute pancreatitis. We present a thirty five year old, diabetic male patient with hypertriglyceridemia induced pancreatitis, enumerating the difficulties in diagnosis and treatment of our patient. A brief review of literature summarizes the various modalities of treatment proposed.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132789118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-01DOI: 10.4103/2348-3113.152321
K. Babu, K. Lakshmaiah, D. Lokanatha, M. Babu, V. Sathyanarayanan, T. Suresh, C. Rao, C. Premalata, L. Abraham, K. Lokesh, N. Sirsath
Background: Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of nonHodgkin′s lymphoma globally with frequent extra nodal involvement. There is sporadic data available on thyroid DLBCL in Indian population and hence we undertook this retrospective observational study at Kidwai Memorial Institute of Oncology, a tertiary care oncology center in India to analyze the clinico biological features of this disease. Methodology: A total of 7 consecutive cases diagnosed as DLBCL by appropriate lymph node biopsy with evidence of thyroid involvement on fine-needle aspiration cytology of thyroid or thyroid histopathology (following thyroidectomy) were confirmed by immunohistochemistry (WHO classification) between January 2008 and September 2013 were included in this study. Results: A total of 7 patients were included in the study. Median age was 65-years (range: 50-72 years), and all were females. Six out of seven were in stage IIAE and one was in stage IVAE. The distribution according to the international prognostic index was as follows: 3 were in low risk, 1 in low-intermediate, 2 in high-intermediate and 1 in high risk group. Regarding treatment, 5 received CHOP, 1 received COP and 1 received no treatment. 5 patients received radiotherapy. 2 patients underwent subtotal thyroidectomy. Of the 6 patients who received chemotherapy radiotherapy, 4 had complete response 1 was lost to follow-up at 3 months and 1 alive with no disease at 32 months), 2 had partial response. The median survival was 15 months (3-32 months). Conclusions: Extranodal thyroid DLBCL presents common in elderly age group and in females. A multimodality treatment approach is used to treat this entity and may improve survival compared with unimodality approach.
{"title":"Diffuse large B-cell lymphoma of the thyroid: Seven cases with review of the literature from India","authors":"K. Babu, K. Lakshmaiah, D. Lokanatha, M. Babu, V. Sathyanarayanan, T. Suresh, C. Rao, C. Premalata, L. Abraham, K. Lokesh, N. Sirsath","doi":"10.4103/2348-3113.152321","DOIUrl":"https://doi.org/10.4103/2348-3113.152321","url":null,"abstract":"Background: Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of nonHodgkin′s lymphoma globally with frequent extra nodal involvement. There is sporadic data available on thyroid DLBCL in Indian population and hence we undertook this retrospective observational study at Kidwai Memorial Institute of Oncology, a tertiary care oncology center in India to analyze the clinico biological features of this disease. Methodology: A total of 7 consecutive cases diagnosed as DLBCL by appropriate lymph node biopsy with evidence of thyroid involvement on fine-needle aspiration cytology of thyroid or thyroid histopathology (following thyroidectomy) were confirmed by immunohistochemistry (WHO classification) between January 2008 and September 2013 were included in this study. Results: A total of 7 patients were included in the study. Median age was 65-years (range: 50-72 years), and all were females. Six out of seven were in stage IIAE and one was in stage IVAE. The distribution according to the international prognostic index was as follows: 3 were in low risk, 1 in low-intermediate, 2 in high-intermediate and 1 in high risk group. Regarding treatment, 5 received CHOP, 1 received COP and 1 received no treatment. 5 patients received radiotherapy. 2 patients underwent subtotal thyroidectomy. Of the 6 patients who received chemotherapy radiotherapy, 4 had complete response 1 was lost to follow-up at 3 months and 1 alive with no disease at 32 months), 2 had partial response. The median survival was 15 months (3-32 months). Conclusions: Extranodal thyroid DLBCL presents common in elderly age group and in females. A multimodality treatment approach is used to treat this entity and may improve survival compared with unimodality approach.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129626383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-01DOI: 10.4103/2348-3113.152331
D. Khosla, R. Mahajan, A. Pandey, K. Dimri, H. Verma, Bhumika Bisht, H. Mohan
Alveolar soft part sarcoma (ASPS) is an enigma both for clinicians and pathologists. It is a rare soft tissue neoplasm affecting young adults. A 72-year-old female presented with a history of painful ulcer on the right side of the oral cavity associated with bleeding and difficulty in chewing. She underwent wide local excision of the lesion with segmental mandibulectomy and supraomohyoid neck dissection. Histopathological examination was suggestive of ASPS with involvement of resection margins. The patient developed rapid relapse after surgery and did not respond to chemotherapy and radiotherapy. She ultimately died of disease 10 months postsurgery.
{"title":"Alveolar soft part sarcoma of the mandible: A rare case","authors":"D. Khosla, R. Mahajan, A. Pandey, K. Dimri, H. Verma, Bhumika Bisht, H. Mohan","doi":"10.4103/2348-3113.152331","DOIUrl":"https://doi.org/10.4103/2348-3113.152331","url":null,"abstract":"Alveolar soft part sarcoma (ASPS) is an enigma both for clinicians and pathologists. It is a rare soft tissue neoplasm affecting young adults. A 72-year-old female presented with a history of painful ulcer on the right side of the oral cavity associated with bleeding and difficulty in chewing. She underwent wide local excision of the lesion with segmental mandibulectomy and supraomohyoid neck dissection. Histopathological examination was suggestive of ASPS with involvement of resection margins. The patient developed rapid relapse after surgery and did not respond to chemotherapy and radiotherapy. She ultimately died of disease 10 months postsurgery.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130685166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-01DOI: 10.4103/2348-3113.152335
S. George, Ahmad Al-Taleb, S. Hussein
Oncology, Gastroenterology and Hepatology Reports| Jul-Dec 2015 | Vol 4 | Issue 2 Sir, Testicular germ cell tumors (TGCT) most often present as masses in the testes but may uncommonly present with symptoms pertaining to the sites of their metastases. In the latter situation, the primary lesion may be clinically unapparent due to small size, central location or a true burned‐out/regressed tumor. The primary tumor can be overlooked in this clinical scenario which may lead to inappropriate patient management.
{"title":"Retrogressed (burned-out) testicular germ cell tumor disguising as duodenal gastrointestinal stromal tumor","authors":"S. George, Ahmad Al-Taleb, S. Hussein","doi":"10.4103/2348-3113.152335","DOIUrl":"https://doi.org/10.4103/2348-3113.152335","url":null,"abstract":"Oncology, Gastroenterology and Hepatology Reports| Jul-Dec 2015 | Vol 4 | Issue 2 Sir, Testicular germ cell tumors (TGCT) most often present as masses in the testes but may uncommonly present with symptoms pertaining to the sites of their metastases. In the latter situation, the primary lesion may be clinically unapparent due to small size, central location or a true burned‐out/regressed tumor. The primary tumor can be overlooked in this clinical scenario which may lead to inappropriate patient management.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131154142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-01DOI: 10.4103/2348-3113.152332
Y. Bashir, Nusrat Bashir, Shabeer Ahmed, S. Geelani, Asif Ahmed, J. Rasool
Myeloid leukemias are a heterogenous group of disease characterized by infiltration of blood, bone marrow and other tissues by neoplastic cells of hematopoietic origin. Rarely, patients may present with symptoms from a mass lesion located in soft tissues. The mass lesion represents a tumor of leukemic cells and is called granulocytic sarcoma or chloroma. This is more commonly seen in monocytic subtype with abnormalities of chromosome 11. In general, they are felt to augur a poorer prognosis, with a poorer response to treatment and worse survival. There have been few case reports of orbital and central nervous system (CNS) chloroma in pediatric age group who have done better than only a medullary disease. Here, we present a case of acute myelogenous leukemia M2 who had two relapses one medullary and one extramedullary (CNS relapse with giant CNS chloroma). Patient was reinduced with same drugs and was advised to go for allogenic stem cell transplantation, which he could not. Subsequently presented with features of raised Intracranial tension (ICT) and was diagnosed to have extramedullary relapse in the form of giant CNS chloroma. He was treated with surgical debulking of the tumor, fludarabine, AraC, idarubicin, and G-CSF chemotherapy protocol (FLAG-IDA) chemo, and local intraspinal triple therapy 5 years back and stands cured at present.
{"title":"Cured case of relapsed acute myeloid leukemia with giant central nervous system chloroma","authors":"Y. Bashir, Nusrat Bashir, Shabeer Ahmed, S. Geelani, Asif Ahmed, J. Rasool","doi":"10.4103/2348-3113.152332","DOIUrl":"https://doi.org/10.4103/2348-3113.152332","url":null,"abstract":"Myeloid leukemias are a heterogenous group of disease characterized by infiltration of blood, bone marrow and other tissues by neoplastic cells of hematopoietic origin. Rarely, patients may present with symptoms from a mass lesion located in soft tissues. The mass lesion represents a tumor of leukemic cells and is called granulocytic sarcoma or chloroma. This is more commonly seen in monocytic subtype with abnormalities of chromosome 11. In general, they are felt to augur a poorer prognosis, with a poorer response to treatment and worse survival. There have been few case reports of orbital and central nervous system (CNS) chloroma in pediatric age group who have done better than only a medullary disease. Here, we present a case of acute myelogenous leukemia M2 who had two relapses one medullary and one extramedullary (CNS relapse with giant CNS chloroma). Patient was reinduced with same drugs and was advised to go for allogenic stem cell transplantation, which he could not. Subsequently presented with features of raised Intracranial tension (ICT) and was diagnosed to have extramedullary relapse in the form of giant CNS chloroma. He was treated with surgical debulking of the tumor, fludarabine, AraC, idarubicin, and G-CSF chemotherapy protocol (FLAG-IDA) chemo, and local intraspinal triple therapy 5 years back and stands cured at present.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114425544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-01DOI: 10.4103/2348-3113.152322
Prakash Bhagat, Sanjoy Roy, D. Lahiri, T. Maji, D. Ray, J. Biswas, P. Chaudhuri
Objective: Analysis was done to assess the implications of total radiation treatment duration towards locally advanced cervical cancer. Methods: A comparative study was conducted in CNCI, Kolkata. A total of 38 patients were studied with interdigited brachyttherapy during the course of conventional teleradiotherapy and they were compared to a total of 39 patients with conventional sequential teletherapy and brachytherapy. Results: In the experimental arm all the patients had complete response to treatment whereas, 24 patients (85.7%) in the conventional arm had complete response [P = 0.08]. At the last follow up 28 patients (73.68%) in the study arm and 17 patients (43.58%) in the control arm were free of disease. The failure rate in the conventional control arm was significantly higher [P = 0.035]. Test of proportion derived from data also showed that the proportion of patients with no evidence of disease at the time of last follow-up was significantly higher in the study arm compared to the control arm [P < 0.05] and the proportion of patients with persistent disease was significantly less in the stuwdy arm compared to the control arm [P < 0.05]. The probability of disease-free survival in percentage according to the curve at the time of median follow-up was approximately 70% for study arm and 60% for control arm [log-rank test, P = 0.2463]. Conclusion: we should hence minimize treatment time and avoid any planned or unplanned interruptions or delays by timely integration of external beam and intra-cavitary irradiation that may yield a better local control in locally advanced cervical cancer.
{"title":"Expedience of conventional radiotherapy in locally advanced cervix cancer: A retrospective analysis","authors":"Prakash Bhagat, Sanjoy Roy, D. Lahiri, T. Maji, D. Ray, J. Biswas, P. Chaudhuri","doi":"10.4103/2348-3113.152322","DOIUrl":"https://doi.org/10.4103/2348-3113.152322","url":null,"abstract":"Objective: Analysis was done to assess the implications of total radiation treatment duration towards locally advanced cervical cancer. Methods: A comparative study was conducted in CNCI, Kolkata. A total of 38 patients were studied with interdigited brachyttherapy during the course of conventional teleradiotherapy and they were compared to a total of 39 patients with conventional sequential teletherapy and brachytherapy. Results: In the experimental arm all the patients had complete response to treatment whereas, 24 patients (85.7%) in the conventional arm had complete response [P = 0.08]. At the last follow up 28 patients (73.68%) in the study arm and 17 patients (43.58%) in the control arm were free of disease. The failure rate in the conventional control arm was significantly higher [P = 0.035]. Test of proportion derived from data also showed that the proportion of patients with no evidence of disease at the time of last follow-up was significantly higher in the study arm compared to the control arm [P < 0.05] and the proportion of patients with persistent disease was significantly less in the stuwdy arm compared to the control arm [P < 0.05]. The probability of disease-free survival in percentage according to the curve at the time of median follow-up was approximately 70% for study arm and 60% for control arm [log-rank test, P = 0.2463]. Conclusion: we should hence minimize treatment time and avoid any planned or unplanned interruptions or delays by timely integration of external beam and intra-cavitary irradiation that may yield a better local control in locally advanced cervical cancer.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121802413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-01DOI: 10.4103/2348-3113.152327
D. Sundriyal, S. Bansal, N. Sharma, S. Manjunath
Peripherally inserted central catheter (PICC) is a drug delivery system frequently utilized in modern oncology practice. Though generally safe and easy to handle, it may be associated with complications. We present an uncommon case of fracture of PICC and subsequent embolization to pulmonary vessels.
{"title":"Fracture-embolization of peripherally inserted central catheter","authors":"D. Sundriyal, S. Bansal, N. Sharma, S. Manjunath","doi":"10.4103/2348-3113.152327","DOIUrl":"https://doi.org/10.4103/2348-3113.152327","url":null,"abstract":"Peripherally inserted central catheter (PICC) is a drug delivery system frequently utilized in modern oncology practice. Though generally safe and easy to handle, it may be associated with complications. We present an uncommon case of fracture of PICC and subsequent embolization to pulmonary vessels.","PeriodicalId":166206,"journal":{"name":"Oncology, Gastroenterology and Hepatology Reports","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122251901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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