Introduction: Sickle cell disease (SCD) is one of the hereditary blood disorders that affects the red blood cells. Several lines of evidence indicated that the vitamin D deficiency (VDD) is quite common in children with SCD and vitamin D supplementation enhanced health-related quality of life in these patients. The present study is aimed to assess the exact prevalence of VDD in SCD patients using meta-analysis. Materials and Methods: A systematic search was conducted in PubMed and Google Scholar to extract the papers that contain prevalence data and numbers of patients with VDD in SCD patients and healthy people. Pooled prevalence was estimated using MAJOR module of Jamovi library. The overall risk ratio of having VDD in patients with SCD was calculated using the Review Manager (RevMan 5.4.1) program. Results: A total of 26 prevalence estimates from 25 papers were included in the meta-analysis. The pooled prevalence of VDD among SCD patients is 60% (95% CIs: 50%-70%). Further, VDD is not significantly different in both SCD patients and healthy controls (risk ratio of 1.28 and 95% CI of 0.81-2.04). Conclusion: Results of this meta-analysis indicate prevalence of VDD in SCD patients. Further, a well-designed, placebo-controlled RCTs have to be conducted to determine the effects and the safety of vitamin D supplementation in children and adults with SCD.
{"title":"Defining vitamin D deficiency in patients with sickle cell disease; A meta-analysis","authors":"Anupama Sahu, Udit Narayan Padhi, L. Bhaskar","doi":"10.34172/jpd.2022.11154","DOIUrl":"https://doi.org/10.34172/jpd.2022.11154","url":null,"abstract":"Introduction: Sickle cell disease (SCD) is one of the hereditary blood disorders that affects the red blood cells. Several lines of evidence indicated that the vitamin D deficiency (VDD) is quite common in children with SCD and vitamin D supplementation enhanced health-related quality of life in these patients. The present study is aimed to assess the exact prevalence of VDD in SCD patients using meta-analysis. Materials and Methods: A systematic search was conducted in PubMed and Google Scholar to extract the papers that contain prevalence data and numbers of patients with VDD in SCD patients and healthy people. Pooled prevalence was estimated using MAJOR module of Jamovi library. The overall risk ratio of having VDD in patients with SCD was calculated using the Review Manager (RevMan 5.4.1) program. Results: A total of 26 prevalence estimates from 25 papers were included in the meta-analysis. The pooled prevalence of VDD among SCD patients is 60% (95% CIs: 50%-70%). Further, VDD is not significantly different in both SCD patients and healthy controls (risk ratio of 1.28 and 95% CI of 0.81-2.04). Conclusion: Results of this meta-analysis indicate prevalence of VDD in SCD patients. Further, a well-designed, placebo-controlled RCTs have to be conducted to determine the effects and the safety of vitamin D supplementation in children and adults with SCD.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79809590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The renin–angiotensin–aldosterone system (RAAS) cascade has a significant effect on several systems. Angiotensin II (AngII) has appeared as not only a vasoactive peptide but also as a multifunctional cytokine that displays several non-hemodynamic properties beyond renal hemodynamic properties. The kidney includes total components of the RAAS such as aldosterone and AngII not only adjust renal hemodynamics and reabsorption of sodium but also activating various inflammatory and fibrotic responses. Inhibition of the RAAS is one of the most potent methods to impede the development of renal diseases such as chronic kidney disease (CKD) and its related problems such as high blood pressure and heart disorders. Aliskiren, an octanamide, nonpeptide piperidine, orally, active, first commercially available, and direct renin inhibitor (DRI), impedes RAAS and operates by attaching to the active sites of renin and may be effective for the management of renal disease because of blocking the RAAS at its point of start and most sensitive step. Based on numerous studies, aliskiren is the greatest powerful inhibitor of AngII extents among RAAS inhibitors, even though it is unable to prevent the (pro) renin receptor-mediated extracellular signal-regulated kinase 1 and 2 (ERK1/2) activations. In this review, it is described renoprotective effects of aliskiren against different types of nephropathy such as acute kidney injury, diabetic nephropathy, and hypertensive nephropathy.
{"title":"Aliskiren in the treatment of renal disease; a narrative review","authors":"B. Roshan, Tella Sadighpour","doi":"10.34172/jpd.2022.11164","DOIUrl":"https://doi.org/10.34172/jpd.2022.11164","url":null,"abstract":"The renin–angiotensin–aldosterone system (RAAS) cascade has a significant effect on several systems. Angiotensin II (AngII) has appeared as not only a vasoactive peptide but also as a multifunctional cytokine that displays several non-hemodynamic properties beyond renal hemodynamic properties. The kidney includes total components of the RAAS such as aldosterone and AngII not only adjust renal hemodynamics and reabsorption of sodium but also activating various inflammatory and fibrotic responses. Inhibition of the RAAS is one of the most potent methods to impede the development of renal diseases such as chronic kidney disease (CKD) and its related problems such as high blood pressure and heart disorders. Aliskiren, an octanamide, nonpeptide piperidine, orally, active, first commercially available, and direct renin inhibitor (DRI), impedes RAAS and operates by attaching to the active sites of renin and may be effective for the management of renal disease because of blocking the RAAS at its point of start and most sensitive step. Based on numerous studies, aliskiren is the greatest powerful inhibitor of AngII extents among RAAS inhibitors, even though it is unable to prevent the (pro) renin receptor-mediated extracellular signal-regulated kinase 1 and 2 (ERK1/2) activations. In this review, it is described renoprotective effects of aliskiren against different types of nephropathy such as acute kidney injury, diabetic nephropathy, and hypertensive nephropathy.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91375175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yasaman Koohshoori, Mohammad Moein Derakhshan Barjoei, Reyhane Izadi, S. Pourrezaei, M. Mousavi
Introduction: Congenital hypothyroidism (CH) is one of the most common endocrine and metabolic disorders and a common preventable cause of mental retardation across the world. This disorder can be prevented if diagnosed and treated before the age of four weeks. Objectives: This study was performed to investigate the incidence rate of CH in infants in Chaharmahal and Bakhtiari province. Patients and Methods: The data of this study were obtained by the CH screening program from 2015 to 2021 in the health deputy of Chaharmahal and Bakhtiari province. Results: A total of 651 patients were diagnosed with CH, which showed an incidence rate of 5.06 per 1000 births (1 per 198 live births) in the province. The highest incidence of the disease was obtained in 2016 and the lowest incidence in 2021. Lordegan city had the highest incidence rate (8.1 per 1000 live births) and Kiar had the lowest one (1.67 per 1000 live births) during the study period. Moreover, the highest and lowest incidence rates in terms of season were observed in winter and summer, respectively. Conclusion: It can be concluded that Chaharmahal and Bakhtiari province, especially Lordegan, is one of the regions with high prevalence of CH in Iran, therefore the incidence rate is not only higher than the national average but also higher than the global average. Hence, the potential causes of this observation deserve further investigation.
{"title":"The incidence of congenital hypothyroidism in neonates born in Chaharmahal and Bakhtiari province from 2015 to 2021; A cross-sectional study","authors":"Yasaman Koohshoori, Mohammad Moein Derakhshan Barjoei, Reyhane Izadi, S. Pourrezaei, M. Mousavi","doi":"10.34172/jpd.2022.10157","DOIUrl":"https://doi.org/10.34172/jpd.2022.10157","url":null,"abstract":"Introduction: Congenital hypothyroidism (CH) is one of the most common endocrine and metabolic disorders and a common preventable cause of mental retardation across the world. This disorder can be prevented if diagnosed and treated before the age of four weeks. Objectives: This study was performed to investigate the incidence rate of CH in infants in Chaharmahal and Bakhtiari province. Patients and Methods: The data of this study were obtained by the CH screening program from 2015 to 2021 in the health deputy of Chaharmahal and Bakhtiari province. Results: A total of 651 patients were diagnosed with CH, which showed an incidence rate of 5.06 per 1000 births (1 per 198 live births) in the province. The highest incidence of the disease was obtained in 2016 and the lowest incidence in 2021. Lordegan city had the highest incidence rate (8.1 per 1000 live births) and Kiar had the lowest one (1.67 per 1000 live births) during the study period. Moreover, the highest and lowest incidence rates in terms of season were observed in winter and summer, respectively. Conclusion: It can be concluded that Chaharmahal and Bakhtiari province, especially Lordegan, is one of the regions with high prevalence of CH in Iran, therefore the incidence rate is not only higher than the national average but also higher than the global average. Hence, the potential causes of this observation deserve further investigation.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90438785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: End-stage renal disease (ESRD) is an important health problem in which chronic, inflammatory, degenerative and irreversible. Objectives: The research was conducted to compare burden of caregivers of hemodialysis (HD) and kidney transplantation (KT) patients. Patients and Methods: This descriptive study was conducted with HD, KT patients and their primary caregivers in a university hospital between July 2019 and June 2020. Power analysis was used to determine the sample size of the study, and a total of 71 HD and 71 KT patients and their caregivers (n=142) were included in the study sample at a confidence interval of 85%. The Zarit Burden Interview (ZBI) scale was used in data collection. The data were analysed by using the SPSS version 22.0 software. Results: As a result of the study, it was determined that the mean caregiver burden score (30.59±13.25) of the caregivers of HD patients was higher than the mean caregiver burden score (22.20±13.95) of the KT patients, and the difference was statistically significant. The difference between socio-demographic characteristics of the caregivers of HD patients and the mean ZBI score was not statistically significant. A statistically significant difference was detected between the age and marital status and the mean ZBI scale scores of the caregivers of patients who underwent KT. Conclusion: As a result of the study, it was found that the care burden of HD patients was higher than the care burden of KT patients. In order to provide holistic care, healthcare professionals need to address the care burden of HD patients.
{"title":"Comparison of care burden of hemodialysis and kidney transplant patients","authors":"İdris Yıldız, Mehtap Kavurmacı","doi":"10.34172/jpd.2022.10151","DOIUrl":"https://doi.org/10.34172/jpd.2022.10151","url":null,"abstract":"Introduction: End-stage renal disease (ESRD) is an important health problem in which chronic, inflammatory, degenerative and irreversible. Objectives: The research was conducted to compare burden of caregivers of hemodialysis (HD) and kidney transplantation (KT) patients. Patients and Methods: This descriptive study was conducted with HD, KT patients and their primary caregivers in a university hospital between July 2019 and June 2020. Power analysis was used to determine the sample size of the study, and a total of 71 HD and 71 KT patients and their caregivers (n=142) were included in the study sample at a confidence interval of 85%. The Zarit Burden Interview (ZBI) scale was used in data collection. The data were analysed by using the SPSS version 22.0 software. Results: As a result of the study, it was determined that the mean caregiver burden score (30.59±13.25) of the caregivers of HD patients was higher than the mean caregiver burden score (22.20±13.95) of the KT patients, and the difference was statistically significant. The difference between socio-demographic characteristics of the caregivers of HD patients and the mean ZBI score was not statistically significant. A statistically significant difference was detected between the age and marital status and the mean ZBI scale scores of the caregivers of patients who underwent KT. Conclusion: As a result of the study, it was found that the care burden of HD patients was higher than the care burden of KT patients. In order to provide holistic care, healthcare professionals need to address the care burden of HD patients.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81242272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), which produces COVID-19, is the most deadly coronavirus ever identified. Essential treatments and nutrition are crucial for improving the immune system against viral infection. As studies recommended checking the nutritional state of COVID-19-infected individuals before treatment, we aimed to review the therapeutic, preventive, and immune-boosting effects of some minerals and vitamins on COVID-19. This review emphasizes the possible therapeutic, preventive, and immune-boosting effects of some minerals such as zinc, selenium, iron, calcium, phosphorus, potassium, and magnesium and vitamins C, D, and E on COVID-19 patients. Regarding the evidence that shows the preventive effects of vitamins and minerals on serious COVID-19, it seems that clinicians have to consider these factors precisely.
{"title":"The therapeutic, preventive, and immune-boosting effects of some minerals and vitamins in COVID-19: A narrative review","authors":"A. Hassanzadeh Rad, Amirhossein Fakhre Yaseri","doi":"10.34172/jpd.2022.9151","DOIUrl":"https://doi.org/10.34172/jpd.2022.9151","url":null,"abstract":"Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), which produces COVID-19, is the most deadly coronavirus ever identified. Essential treatments and nutrition are crucial for improving the immune system against viral infection. As studies recommended checking the nutritional state of COVID-19-infected individuals before treatment, we aimed to review the therapeutic, preventive, and immune-boosting effects of some minerals and vitamins on COVID-19. This review emphasizes the possible therapeutic, preventive, and immune-boosting effects of some minerals such as zinc, selenium, iron, calcium, phosphorus, potassium, and magnesium and vitamins C, D, and E on COVID-19 patients. Regarding the evidence that shows the preventive effects of vitamins and minerals on serious COVID-19, it seems that clinicians have to consider these factors precisely.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88406734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Considering the importance of the anesthesia and surgery team’s awareness of possible hemodynamic changes when using bone cement and preventing its risks, it is very important to know about this issue. Objectives: This study aimed to identify and prevent the risks of possible hemodynamic changes and related factors when using bone cement in knee arthroplasty candidates. Patient and Methods: This descriptive-analytical study of 63 knee arthroplasty candidates in Imam Reza and Shohada hospitals (affiliated with the Tabriz university of medical sciences) was conducted in 2020. The hemodynamic status (heart rate, blood pressure, and arterial oxygen saturation (SaO2 )) of all patients was recorded and changes were calculated three minutes before, during, and three minutes after using bone cement. Results: The increase in diastolic (P=0.221) and systolic (P=0.195) blood pressure and heart rate (P=0.125) over time (before and after using bone cement) was statistically insignificant. However, the arterial oxygen saturation of patients remained constant (P=0.999). Conclusion: The results showed that using bone cement causes minor changes in (systolic and diastolic) blood pressure and heart rate.
{"title":"Hemodynamic changes and related factors in bone cement implantation syndrome in knee arthroplasty candidates","authors":"A. Moradi, N. Abedini","doi":"10.34172/jpd.2022.9146","DOIUrl":"https://doi.org/10.34172/jpd.2022.9146","url":null,"abstract":"Introduction: Considering the importance of the anesthesia and surgery team’s awareness of possible hemodynamic changes when using bone cement and preventing its risks, it is very important to know about this issue. Objectives: This study aimed to identify and prevent the risks of possible hemodynamic changes and related factors when using bone cement in knee arthroplasty candidates. Patient and Methods: This descriptive-analytical study of 63 knee arthroplasty candidates in Imam Reza and Shohada hospitals (affiliated with the Tabriz university of medical sciences) was conducted in 2020. The hemodynamic status (heart rate, blood pressure, and arterial oxygen saturation (SaO2 )) of all patients was recorded and changes were calculated three minutes before, during, and three minutes after using bone cement. Results: The increase in diastolic (P=0.221) and systolic (P=0.195) blood pressure and heart rate (P=0.125) over time (before and after using bone cement) was statistically insignificant. However, the arterial oxygen saturation of patients remained constant (P=0.999). Conclusion: The results showed that using bone cement causes minor changes in (systolic and diastolic) blood pressure and heart rate.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78549701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: There are limited studies with contradictory results on the relationship between vitamin D and calcium levels with dental caries at different ages. Objectives: Given the contradictory results of studies and the importance of preventing the onset and progression of dental caries for oral health, this study aimed to find the relationship between vitamin D and calcium levels with dental caries in 6-12 years old children. Patients and Methods: This descriptive-cross sectional study was conducted from 2019 to 2020 on 256 children of 6-12 years old referring to children’s hospital in Tabriz. Serum vitamin D (sufficient, insufficient or deficient) and calcium (sufficient, insufficient) levels were measured for each child, and the relationship between their levels and dental caries was investigated by descriptive and inferential statistical tests. Results: The dental index of decayed, missing and filled teeth (DMFT) in the deficient and insufficient vitamin D groups was significantly higher than in the sufficient vitamin D group (P=0.03). The linear regression model on the effect of age, vitamin D, and calcium on dental indexes showed no significant statistical relationship. However, in the case of the dental index, age, and calcium level affected dental caries (d), but vitamin D did not affect this index. Conclusion: There was no significant relationship between calcium and vitamin D serum levels with dental caries in 6-12 years old children.
{"title":"The relationship between vitamin D and calcium serum levels with dental caries in 6-12 years old children","authors":"L. Saboktakin","doi":"10.34172/jpd.2022.9141","DOIUrl":"https://doi.org/10.34172/jpd.2022.9141","url":null,"abstract":"Introduction: There are limited studies with contradictory results on the relationship between vitamin D and calcium levels with dental caries at different ages. Objectives: Given the contradictory results of studies and the importance of preventing the onset and progression of dental caries for oral health, this study aimed to find the relationship between vitamin D and calcium levels with dental caries in 6-12 years old children. Patients and Methods: This descriptive-cross sectional study was conducted from 2019 to 2020 on 256 children of 6-12 years old referring to children’s hospital in Tabriz. Serum vitamin D (sufficient, insufficient or deficient) and calcium (sufficient, insufficient) levels were measured for each child, and the relationship between their levels and dental caries was investigated by descriptive and inferential statistical tests. Results: The dental index of decayed, missing and filled teeth (DMFT) in the deficient and insufficient vitamin D groups was significantly higher than in the sufficient vitamin D group (P=0.03). The linear regression model on the effect of age, vitamin D, and calcium on dental indexes showed no significant statistical relationship. However, in the case of the dental index, age, and calcium level affected dental caries (d), but vitamin D did not affect this index. Conclusion: There was no significant relationship between calcium and vitamin D serum levels with dental caries in 6-12 years old children.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80239192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The thyroid gland is a crucial component of the body’s glandular system and metabolism, which is exposed to unnecessary radiation as an organ at risk in radiation therapy to the head, neck, and chest. Radiation can lead to thyroid dysfunction such as hypothyroidism and thyroid cancer.
{"title":"Evaluation of radiation side effects on thyroid function","authors":"Kolsoum Teimouri, Samaneh Pakravan, Elham Rahmatinia, Kamran Azadbakht","doi":"10.34172/jpd.2022.9145","DOIUrl":"https://doi.org/10.34172/jpd.2022.9145","url":null,"abstract":"The thyroid gland is a crucial component of the body’s glandular system and metabolism, which is exposed to unnecessary radiation as an organ at risk in radiation therapy to the head, neck, and chest. Radiation can lead to thyroid dysfunction such as hypothyroidism and thyroid cancer.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"186 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79619905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
One of the most prevalent endocrine system disorders with lifetime repercussions on health is hypothyroidism. Due to inadequate thyroid secretion, this illness results in thyroid dysfunction. One of the common liver ailments, non-alcoholic fatty liver disease (NAFLD), denotes the buildup of fat in the liver without consuming alcohol. NAFLD and hypothyroidism frequently coexist, and the development of NAFLD may be influenced by the condition.
{"title":"Examining the relationship between non-alcoholic fatty liver disease and hypothyroidism","authors":"Kolsoum Teimouri, Samaneh Pakravan, Kamran Azadbakht","doi":"10.34172/jpd.2022.9148","DOIUrl":"https://doi.org/10.34172/jpd.2022.9148","url":null,"abstract":"One of the most prevalent endocrine system disorders with lifetime repercussions on health is hypothyroidism. Due to inadequate thyroid secretion, this illness results in thyroid dysfunction. One of the common liver ailments, non-alcoholic fatty liver disease (NAFLD), denotes the buildup of fat in the liver without consuming alcohol. NAFLD and hypothyroidism frequently coexist, and the development of NAFLD may be influenced by the condition.","PeriodicalId":16657,"journal":{"name":"Journal of Parathyroid Disease","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87348337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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