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FSH Receptor Variant: An Unusual Cause of Secondary Amenorrhea FSH受体变异:继发性闭经的不寻常原因。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 DOI: 10.1016/j.jpag.2025.06.002
Oluwatosin O. Cooper (Tosin) MD, MPH , Elisabeth H. Quint MD , Yolanda R. Smith MD , Melina L. Dendrinos MD

Introduction

Secondary amenorrhea with high Follicle Stimulating Hormone (FSH) levels and low estradiol is typically diagnosed as primary ovarian insufficiency (POI) in individuals under the age of 40. Low anti-mullerian hormone (AMH) levels support the diagnosis of POI, but normal AMH levels warrant additional evaluation.

Case Presentation

A 19-year-old female with menarche at age 12 experienced secondary amenorrhea at age 14.5. Initial evaluation showed elevated gonadotropins and low estradiol, which were confirmed on repeat testing. Normal karyotype, no FMR1 repeat expansion, negative autoimmune markers, and normal AMH levels were found. Genetic testing revealed two Follicle Stimulating Hormone Receptor (FSHR) gene variants with high suspicion of pathogenicity.

Discussion

Pathogenic variants in the FSHR gene are an uncommon cause of secondary amenorrhea. Atypical POI cases with a normal AMH level should be evaluated with a genetic consultation.
导语:继发性闭经伴高促卵泡激素(FSH)水平和低雌二醇通常诊断为原发性卵巢功能不全(POI)在40岁以下的个体。低抗苗勒管激素(AMH)水平支持POI的诊断,但正常的AMH水平需要额外的评估。病例介绍:一名19岁女性,12岁初潮,14.5岁继发性闭经。初步评估显示促性腺激素升高和雌二醇低,这在重复测试中得到证实。核型正常,无FMR1重复扩增,自身免疫标记阴性,AMH水平正常。基因检测显示两种促卵泡激素受体(FSHR)基因变异具有高致病性。讨论:FSHR基因的致病性变异是继发性闭经的罕见原因。AMH水平正常的非典型POI病例应通过遗传咨询进行评估。
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引用次数: 0
Laparoscopic Management of Tubercular Pyosalpinx Torsion in an Adolescent Girl: A Case Report 腹腔镜下治疗青春期女孩输卵管结核性扭转1例。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 DOI: 10.1016/j.jpag.2025.10.002
Avantika Gupta MBBS, MS, MRCOG, Satish Choudhury MBBS, MS, DNB, Vandana Kattimani MBBS, Deepika Mangani MBBS
Female genital tuberculosis (FGTB) is a form of extrapulmonary tuberculosis that predominantly affects women of reproductive age and is a significant cause of infertility in TB-endemic countries such as India. Tubercular pyosalpinx is a rare presentation of FGTB. Even more uncommon is its complication by isolated tubal torsion, which may mimic other causes of acute abdomen, making early diagnosis challenging.
We report the case of a 15-year-old girl who presented with acute lower abdominal pain and vomiting. She had a 2-month history of low-grade evening fever. Clinical evaluation and ultrasound findings suggested pyosalpinx or hematosalpinx with normal ovarian morphology, raising suspicion of isolated tubal torsion. Diagnostic laparoscopy revealed a torsed, distended fallopian tube filled with purulent material and multiple peritoneal tubercles. The tube was excised using a glove-made improvised endobag to prevent intra-abdominal spillage. Histopathology confirmed tubercular salpingitis with caseous necrosis, and GeneXpert was positive for Mycobacterium tuberculosis. The patient was started on standard anti-tubercular therapy and had an uneventful recovery.
This case underscores the importance of considering tuberculosis as an etiology in adolescent girls presenting with pyosalpinx, especially in TB-endemic regions. It also highlights the value of safe laparoscopic management with innovative surgical techniques in resource-limited settings. Early diagnosis, surgical intervention, and timely initiation of anti-tubercular therapy are crucial for effective management and preservation of reproductive health.
女性生殖器结核病(FGTB)是一种肺外结核,主要影响育龄妇女,在印度等结核病流行国家是导致不孕症的重要原因。结节性脓输卵管炎是FGTB的罕见表现。更罕见的并发症是孤立的输卵管扭转,这可能类似于其他急腹症的原因,使早期诊断具有挑战性。我们报告的情况下,一个15岁的女孩谁提出急性下腹痛和呕吐。她有两个月的低烧史。临床及超声检查提示卵巢形态正常的脓输卵管或血输卵管,怀疑为孤立性输卵管扭转。诊断性腹腔镜检查显示输卵管扭曲、膨胀,充满化脓性物质和多个腹膜结节。使用手套制作的临时内袋切除管,以防止腹腔内溢出。组织病理学证实结核性输卵管炎伴干酪样坏死,GeneXpert检测结核分枝杆菌阳性。患者开始接受标准的抗结核治疗,并顺利康复。本病例强调了将结核作为一种病因在出现脓输卵管炎的青春期女孩中考虑的重要性,特别是在结核病流行地区。它还强调了安全的腹腔镜管理与创新的外科技术在资源有限的设置的价值。早期诊断、手术干预和及时开始抗结核治疗对于有效管理和维护生殖健康至关重要。
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引用次数: 0
A Scoping Review of Barriers to Accessing Abortions among Adolescents in the United States 对美国青少年堕胎障碍的范围审查。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 DOI: 10.1016/j.jpag.2025.10.003
Julie Maslowsky PhD , Naomi Harada Thyden PhD, MPH , Renee Odom-Konja MPH , Catherine Gimbrone MPH , Joanna Paul MPH, MSW , Eleanor Esbrook MD , Rosie Hanneke MLS , Laura D. Lindberg PhD

Study Objective

Even before the Dobbs Supreme Court decision, minors experienced a wide variety of barriers to abortion care in the United States, including legal, financial, cultural, transportation, and misinformation barriers as well as pressure from parents and partners. This scoping review summarizes the literature on barriers to abortion among minors in the United States prior to the Dobbs decision.

Methods

We conducted a database search to identify original research in the United States published between 2007 and 2022. We included quantitative and qualitative empirical articles and assessed their quality. We created categories for the barriers to abortion among minors identified in the articles. We screened 7584 records and included 70 articles in the scoping review. We charted study aims, study designs, data sources, analytic samples, and results.

Results

The articles explored factors related to abortion access and identified several categories of barriers to abortion among minors. These included legal barriers (41 articles found them to be a barrier), financial barriers (14 articles), cultural barriers (13 articles), transportation barriers (12 articles), pressure from parents (11 articles), misinformation (8 articles), and pressure from a partner (8 articles). Legal barriers, including laws that require minors to inform or get permission from an adult guardian, were the most commonly identified barrier.

Conclusion

These findings suggest that minors need policy and interpersonal support to overcome general and age-specific barriers to abortion care. Future research should examine if and how barriers for minors have intensified post-Dobbs, informing targeted policy responses.
研究目的:即使在多布斯最高法院判决之前,未成年人在美国经历了各种各样的堕胎护理障碍,包括法律,经济,文化,交通和错误信息障碍以及来自父母和伴侣的压力。本综述总结了多布斯案判决前美国未成年人堕胎障碍的文献。方法:我们进行了数据库检索,以确定2007年至2022年在美国发表的原创研究。我们纳入了定量和定性的实证文章,并评估了它们的质量。我们对文章中确定的未成年人堕胎障碍进行了分类。我们筛选了7584条记录,并将70篇文章纳入范围综述。我们绘制了研究目的、研究设计、数据来源、分析样本和结果的图表。结果:本文探讨了影响未成年人堕胎的因素,并确定了未成年人堕胎的几类障碍。这些障碍包括法律障碍(41篇文章认为它们是障碍)、经济障碍(14篇文章)、文化障碍(13篇文章)、交通障碍(12篇文章)、来自父母的压力(11篇文章)、错误信息(8篇文章)和来自伴侣的压力(8篇文章)。法律障碍,包括要求未成年人告知或获得成年监护人许可的法律,是最常见的障碍。结论:这些研究结果表明,未成年人需要政策和人际支持来克服一般和特定年龄的堕胎护理障碍。未来的研究应该检查未成年人的障碍是否以及如何在多布斯事件后加剧,为有针对性的政策反应提供信息。
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引用次数: 0
Multi-Site Pain During Menstruation in Adolescents is Associated With Impaired Functioning Across Various Domains: A Cross-Sectional Observational Study 青少年月经期间的多部位疼痛与各领域功能受损有关:一项横断面观察研究。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 DOI: 10.1016/j.jpag.2025.10.009
Laura C. Seidman BS , Laura A. Payne PhD

Study Objective

To evaluate multi-site pain (i.e., number of painful body regions) during menstruation in a sample of adolescents, and to assess relationships between multi-site pain during menstruation and other menstrual cycle, pain, and psychosocial factors.

Methods

Participants in this cross-sectional observational study included 141 girls ages 13-19 years with varying levels of menstrual pain. Participants indicated on a body map the areas where they usually experience pain when menstruating. Participants also completed a set of validated self-report questionnaires. Menstruation-associated multi-site pain was calculated as the total number of body regions reported (out of 21). Partial correlations controlling for baseline menstrual pain intensity were conducted between menstruation-associated multi-site pain and other variables of interest.

Results

The average number of body regions reported was 2.8 (SD = 1.5; min = 0; max = 8). Menstruation-associated multi-site pain was significantly positively correlated with number of pre-menstrual syndrome symptoms, non-menstrual multi-site body pain, pain interference over the prior week, fatigue, sleep disturbance, somatization, and multisensory sensitivity. Menstruation-associated multi-site pain was not significantly correlated with age, age at menarche, gynecologic age, menstrual pain interference, and non-menstrual body pain intensity.

Conclusion

Pain during menstruation in adolescents is not limited to the abdominal and pelvic regions, and many girls experience pain in numerous body locations during their periods. The associations between menstruation-associated multi-site pain and other pain and psychosocial measures provide preliminary evidence for the existence of a sub-group of adolescents who may be at increased risk for future pain problems.
研究目的:评估青少年月经期间的多部位疼痛(即身体疼痛区域的数量),并评估月经期间多部位疼痛与其他月经周期、疼痛和社会心理因素之间的关系。方法:这项横断面观察性研究的参与者包括141名年龄在13-19岁之间的女孩,她们有不同程度的月经疼痛。参与者在一张身体地图上标出她们经期通常感到疼痛的部位。参与者还完成了一套有效的自我报告问卷。月经相关的多部位疼痛计算为报告的身体区域总数(共21个)。在月经相关的多部位疼痛和其他感兴趣的变量之间进行了控制基线月经疼痛强度的部分相关。结果:报告的身体区域数平均为2.8个(SD=1.5; min=0; max=8)。经期相关多部位疼痛与经前综合征症状、非经期多部位身体疼痛、前一周疼痛干扰、疲劳、睡眠障碍、躯体化和多感觉敏感性显著正相关。经期相关多部位疼痛与年龄、初潮年龄、妇科年龄、经期疼痛干扰、非经期身体疼痛强度无显著相关。结论:青少年经期疼痛并不局限于腹部和骨盆区域,许多女孩在经期的许多身体部位都会感到疼痛。经期相关的多部位疼痛与其他疼痛和社会心理测量之间的关联为存在一个青少年亚群提供了初步证据,该亚群可能会增加未来疼痛问题的风险。
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引用次数: 0
Postpartum Contraception Use among Adolescent Mothers 青少年母亲产后避孕措施的使用。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 DOI: 10.1016/j.jpag.2025.10.011
Julie Maslowsky PhD , Eleanor Esbrook MD , Renee Odom-Konja MPH , Haley Stritzel PhD , Catherine Gimbrone MPH , Dorothy Mandell PhD

Study Objective

To describe patterns of postpartum contraception use among primiparous and multiparous adolescent mothers.

Methods

Cross-sectional data came from the Pregnancy Risk Assessment Monitoring System Phase 7 (2012-2015). The analytic sample included postpartum respondents ages 15-19 in 40 US states (N = 5535). Exposures included age, race, parity, intimate partner violence, psychosocial stressors, prenatal care utilization, postpartum home health visits, and insurance type. The primary outcome was postpartum use of effective contraception. The secondary outcome was reasons for not using postpartum contraception.

Results

Adolescents who attended postpartum check-ups (AOR = 2.12; 95% CI 1.58-2.84) or received home health visits (AOR = 1.37; 95% CI 1.06-1.77) were more likely to use effective contraception postpartum, whereas those experiencing more stressors were less likely (AOR = 0.93; 95% CI: 0.86-1.00). Non-Hispanic Black adolescents were less likely to use effective contraception (AOR = 0.69; 95% CI 0.50-0.94) compared to non-Hispanic White adolescents. Among those who did not use contraception postpartum, having a postpartum home health visit was associated with lower odds of endorsing contraceptive side effects (AOR = 0.33; 95% CI 0.18-0.60) or not wishing to use contraception (AOR = 0.43; 95% CI 0.22-0.86) as reasons for nonuse.

Conclusion

Access to postpartum care via home health and postpartum clinic visits was associated with significantly higher likelihood of using effective contraception. However, disparities persisted among non-Hispanic Black adolescents and those experiencing high levels of psychosocial stress. For postpartum adolescents who do not desire a subsequent birth, increasing their ability to obtain effective contraceptives can be achieved through increased access to postpartum care, particularly for underserved populations.
研究目的:描述初产和多产青少年母亲产后避孕的使用模式。方法:横断面数据来自妊娠风险评估监测系统第7期(2012-2015)。分析样本包括美国40个州15-19岁的产后受访者(N= 5535)。暴露因素包括年龄、种族、胎次、亲密伴侣暴力、心理社会压力源、产前护理利用、产后家庭健康访问和保险类型。主要结局是产后有效避孕的使用情况。次要结果是未使用产后避孕措施的原因。结果:参加产后检查(AOR=2.12; 95% CI: 1.58-2.84)或接受家庭健康访问(AOR=1.37; 95% CI: 1.06-1.77)的青少年更有可能在产后使用有效的避孕措施,而经历更多压力源的青少年更不可能(AOR=0.93; 95% CI: 0.86-1.00)。与非西班牙裔白人青少年相比,非西班牙裔黑人青少年较少使用有效避孕措施(AOR=0.69; 95% CI 0.50-0.94)。在那些产后没有使用避孕措施的妇女中,产后家庭健康访问与赞同避孕副作用(AOR=0.33; 95% CI 0.18-0.60)或不希望使用避孕措施(AOR=0.43; 95% CI 0.22-0.86)作为不使用原因的几率较低相关。结论:通过家庭保健和产后门诊就诊获得产后护理与使用有效避孕措施的可能性显著增加相关。然而,在非西班牙裔黑人青少年和那些经历高水平社会心理压力的青少年中,差异仍然存在。对于不希望再生育的产后青少年,可以通过增加获得产后护理的机会来提高他们获得有效避孕药具的能力,特别是对服务不足的人群。
{"title":"Postpartum Contraception Use among Adolescent Mothers","authors":"Julie Maslowsky PhD ,&nbsp;Eleanor Esbrook MD ,&nbsp;Renee Odom-Konja MPH ,&nbsp;Haley Stritzel PhD ,&nbsp;Catherine Gimbrone MPH ,&nbsp;Dorothy Mandell PhD","doi":"10.1016/j.jpag.2025.10.011","DOIUrl":"10.1016/j.jpag.2025.10.011","url":null,"abstract":"<div><h3>Study Objective</h3><div>To describe patterns of postpartum contraception use among primiparous and multiparous adolescent mothers.</div></div><div><h3>Methods</h3><div>Cross-sectional data came from the Pregnancy Risk Assessment Monitoring System Phase 7 (2012-2015). The analytic sample included postpartum respondents ages 15-19 in 40 US states (<em>N</em> = 5535). Exposures included age, race, parity, intimate partner violence, psychosocial stressors, prenatal care utilization, postpartum home health visits, and insurance type. The primary outcome was postpartum use of effective contraception. The secondary outcome was reasons for not using postpartum contraception.</div></div><div><h3>Results</h3><div>Adolescents who attended postpartum check-ups (AOR = 2.12; 95% CI 1.58-2.84) or received home health visits (AOR = 1.37; 95% CI 1.06-1.77) were more likely to use effective contraception postpartum, whereas those experiencing more stressors were less likely (AOR = 0.93; 95% CI: 0.86-1.00). Non-Hispanic Black adolescents were less likely to use effective contraception (AOR = 0.69; 95% CI 0.50-0.94) compared to non-Hispanic White adolescents. Among those who did not use contraception postpartum, having a postpartum home health visit was associated with lower odds of endorsing contraceptive side effects (AOR = 0.33; 95% CI 0.18-0.60) or not wishing to use contraception (AOR = 0.43; 95% CI 0.22-0.86) as reasons for nonuse.</div></div><div><h3>Conclusion</h3><div>Access to postpartum care via home health and postpartum clinic visits was associated with significantly higher likelihood of using effective contraception. However, disparities persisted among non-Hispanic Black adolescents and those experiencing high levels of psychosocial stress. For postpartum adolescents who do not desire a subsequent birth, increasing their ability to obtain effective contraceptives can be achieved through increased access to postpartum care, particularly for underserved populations.</div></div>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"39 1","pages":"Pages 76-83"},"PeriodicalIF":1.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145401321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Focal Adenomyosis in a 17-Year-Old Patient: A Case Report 17岁患者局灶性脑卒中1例报告
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 DOI: 10.1016/j.jpag.2025.10.007
Maja Banović MD, PhD , Dina Gržan MD , Vladimir Banović MD, PhD
{"title":"Focal Adenomyosis in a 17-Year-Old Patient: A Case Report","authors":"Maja Banović MD, PhD ,&nbsp;Dina Gržan MD ,&nbsp;Vladimir Banović MD, PhD","doi":"10.1016/j.jpag.2025.10.007","DOIUrl":"10.1016/j.jpag.2025.10.007","url":null,"abstract":"","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"39 1","pages":"Pages 135-136"},"PeriodicalIF":1.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146102860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Authors’ Response to “Responding to Adolescents’ Emotional Needs in Abortion: The Importance of Empathy-Based Counseling and Flexible Choice” 作者对“应对青少年堕胎中的情感需求:移情咨询和灵活选择的重要性”的回应
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 DOI: 10.1016/j.jpag.2025.08.004
Laura Kirkpatrick MD
{"title":"Authors’ Response to “Responding to Adolescents’ Emotional Needs in Abortion: The Importance of Empathy-Based Counseling and Flexible Choice”","authors":"Laura Kirkpatrick MD","doi":"10.1016/j.jpag.2025.08.004","DOIUrl":"10.1016/j.jpag.2025.08.004","url":null,"abstract":"","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"39 1","pages":"Page 147"},"PeriodicalIF":1.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146102858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of No-Test Medication Abortions in Primary Care: A Roadmap from an Adolescent and Young Adult Medicine Clinic 实施无测试药物流产在初级保健:路线图从青少年和青年医学诊所。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 DOI: 10.1016/j.jpag.2025.09.014
Julia H. Raney MD , Amanda E. Bryson MD, MPH , Chelsea A. Garnett MD , Lisa Mihaly FNP, MS , Sara M. Buckelew MD, MPH , Marissa Raymond-Flesch MD, MPH

Study Objective

Over 2 years post-Roe, 22 states have banned or significantly limited abortion access, exacerbating existing structural barriers to abortions for adolescents and young adults (AYAs), including cost, transportation, parental notification requirements, and confidentiality concerns. We provide a roadmap for and demonstrate the feasibility of implementing no-test medication abortions (MABs) to expand abortion access in an adolescent-focused pediatric primary care setting.

Methods

An interdisciplinary team in an AYA-focused primary care clinic developed and implemented a no-test MAB protocol. Iterative rounds of protocol development engaged stakeholders including hospital leadership, OBGYN consultants, nurses, and program directors for residency, fellowship, and nursing trainees. Frequent interdisciplinary debriefs identified facilitators, barriers, and solutions to optimize care.

Results

Over 6 months, we identified clinic champions, built relationships with key stakeholders, developed clinic protocols, and disseminated MAB clinical training. In our first 6 months of implementation, we provided 4 MABs. Facilitators identified by staff include provider expertise in AYA development and patient and parent preferences for MABs in their medical home. System-level barriers (eg, timely scheduling challenges), staff factors (eg, fear of complications), and patient factors (eg, ambivalence about pregnancy) were identified. Solutions developed include establishing scheduling procedures, formalizing consultative pathways with gynecology, and integrating social work support.

Conclusion

It is feasible for adolescent primary care practices to provide no-test MABs. Through interdisciplinary planning and iterative design, barriers from the health system, clinic staff, and patient levels can be identified and addressed, expanding equitable access to safe, AYA-focused abortion care.
研究目标:在roe案件发生后的两年多时间里,22个州禁止或严重限制了堕胎机会,加剧了青少年和年轻人(AYA)堕胎的现有结构性障碍,包括成本、交通、父母通知要求和保密问题。我们提供了一个路线图,并证明了实施无测试药物流产(mab)的可行性,以扩大流产获得在青少年为重点的儿科初级保健设置。方法:一个跨学科的团队在一个以aya为重点的初级保健诊所开发并实施了一个无测试的MAB协议。反复的协议制定涉及到包括医院领导、妇产科顾问、护理、住院医师项目主管、奖学金和护理实习生在内的利益相关者。频繁的跨学科汇报确定了优化护理的促进因素、障碍和解决方案。结果:在6个月的时间里,我们确定了临床冠军,与主要利益相关者建立了关系,制定了临床方案,并传播了MAB临床培训。在我们实施的前6个月,我们提供了4个单克隆抗体。工作人员确定的促进因素包括提供人员在AYA开发方面的专业知识以及患者和家长在其医疗家中对单克隆抗体的偏好。确定了系统层面的障碍(如及时安排的挑战)、工作人员因素(如对并发症的恐惧)和患者因素(如对怀孕的矛盾心理)。制定的解决方案包括建立日程安排程序,与妇科正式协商途径,以及整合社会工作支持。结论:在青少年初级保健机构中提供免检测单克隆抗体是可行的。通过跨学科规划和迭代设计,可以确定和解决来自卫生系统、诊所工作人员和患者层面的障碍,扩大公平获得安全、以人工流产为重点的人工流产护理的机会。
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引用次数: 0
Perforated Rotated Mesenteric Cyst Presenting as Acute Abdominal Pain in a Female Pediatric Patient: A Case Report 穿孔旋转肠系膜囊肿表现为急性腹痛的女儿科患者:一个病例报告。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 DOI: 10.1016/j.jpag.2025.09.011
Valerie Josephine Dirjayanto MRes , Astrid Indrafebrina Sugianto MD, BMedSci , Riana Pauline Tamba MD, PhD

Introduction

Although more than half of cases are asymptomatic or mild in symptoms, mesenteric cysts can present clinically and radiologically similar to gynecologic diseases.

Case

A female child presented with worsening episodes of abdominal pain 1 day before admission. Abdominal x-ray suggested mechanical obstruction of the small bowel, and CT scan suggested ileal abnormality.

Discussion

During open surgery, we found 2 rotated chylous mesenteric cysts, accompanied by adhesions and jejunal perforation 57 cm from the ligament of Treitz. Cyst excision, adhesiolysis, ileo-ileal resection, and anastomosis were performed.

Conclusion

Although rare and challenging to identify, mesenteric cysts should be kept in the differential diagnosis of female children presenting with abdominal pain.
简介:虽然超过一半的病例无症状或症状轻微,但肠系膜囊肿的临床和放射学表现与妇科疾病相似。病例说明:一女患儿入院前1天腹痛加重。腹部x线提示机械性小肠梗阻,CT提示回肠异常。讨论:在开放手术中,我们发现两个旋转的乳糜肠系膜囊肿,伴粘连和空肠穿孔,距Treitz韧带57厘米。行囊肿切除、粘连松解、回肠-回肠切除术、吻合术。结论:虽然肠系膜囊肿罕见且难以识别,但在以腹痛为表现的女性儿童中应保留其鉴别诊断。
{"title":"Perforated Rotated Mesenteric Cyst Presenting as Acute Abdominal Pain in a Female Pediatric Patient: A Case Report","authors":"Valerie Josephine Dirjayanto MRes ,&nbsp;Astrid Indrafebrina Sugianto MD, BMedSci ,&nbsp;Riana Pauline Tamba MD, PhD","doi":"10.1016/j.jpag.2025.09.011","DOIUrl":"10.1016/j.jpag.2025.09.011","url":null,"abstract":"<div><h3>Introduction</h3><div>Although more than half of cases are asymptomatic or mild in symptoms, mesenteric cysts can present clinically and radiologically similar to gynecologic diseases.</div></div><div><h3>Case</h3><div>A female child presented with worsening episodes of abdominal pain 1 day before admission. Abdominal x-ray suggested mechanical obstruction of the small bowel, and CT scan suggested ileal abnormality.</div></div><div><h3>Discussion</h3><div>During open surgery, we found 2 rotated chylous mesenteric cysts, accompanied by adhesions and jejunal perforation 57 cm from the ligament of Treitz. Cyst excision, adhesiolysis, ileo-ileal resection, and anastomosis were performed.</div></div><div><h3>Conclusion</h3><div>Although rare and challenging to identify, mesenteric cysts should be kept in the differential diagnosis of female children presenting with abdominal pain.</div></div>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"39 1","pages":"Pages 137-140"},"PeriodicalIF":1.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving Minimally Invasive Surgical Approaches to Large Adnexal Masses in Pediatric Gynecology: Combining Mini-Laparotomy With Single Port Laparoscopy 改进小儿妇科大附件肿物的微创手术入路:小剖腹与单口腹腔镜相结合。
IF 1.8 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2026-02-01 DOI: 10.1016/j.jpag.2025.09.012
Megan F. Sumida MD , Olivia K. Winfrey MD, MPH , Julie Hakim MD , Jennifer E. Dietrich MD, MSc
In pediatric populations large ovarian cysts are often benign, and minimally invasive approaches are preferred to minimize perioperative pain and recovery, allow for same day discharge, and improve incision cosmesis. Ovarian preservation is also prioritized and cystectomy is preferred over oophorectomy. While tactile sensation and dexterity are improved in mini laparotomy cases, there are limitations with visualization that are improved with laparoscopy. We describe a technique that employs both diagnostic laparoscopy and mini laparotomy using the GelPOINT Mini™ Advanced Access Platform for single site laparoscopy in pediatric patients. This case series includes cysts ranging 7-24 cm with benign preoperative risk stratification, in patients aged 3-16 years, who underwent successful same-day, ovarian-sparing surgery with the benefits of both open and laparoscopic procedures.
在儿科人群中,较大的卵巢囊肿通常是良性的,微创方法可以最大限度地减少围手术期疼痛和恢复,允许当天出院,并改善切口美容。卵巢保存也是优先考虑的,膀胱切除术优于卵巢切除术。虽然在小型剖腹手术病例中触觉和灵活性得到了改善,但腹腔镜手术改善了视觉上的局限性。我们描述了一种使用GelPOINT mini™高级访问平台进行儿科患者单部位腹腔镜检查的诊断腹腔镜和迷你剖腹手术技术。本病例系列包括7-24厘米的囊肿,术前良性风险分层,患者年龄3至16岁,接受了成功的当天卵巢保留手术,开放和腹腔镜手术均有好处。
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引用次数: 0
期刊
Journal of pediatric and adolescent gynecology
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