Pub Date : 2020-12-13DOI: 10.3329/jninb.v6i2.50743
Q. Mohammad, M. E. Hussain
Abstract not available Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 72-73
孟加拉国家神经科学研究所杂志,2020;6(2):72-73
{"title":"Neurological Manifestations in COVID-19 Patients: Bangladesh Perspective","authors":"Q. Mohammad, M. E. Hussain","doi":"10.3329/jninb.v6i2.50743","DOIUrl":"https://doi.org/10.3329/jninb.v6i2.50743","url":null,"abstract":"Abstract not available \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 72-73","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73630821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-05DOI: 10.3329/jninb.v6i1.48028
A. Bhuiyan, Z. Sultana, M. Khan, A. M. Rahman, M. R. Ahsan, M. M. Rahmam, K. Hasan, M. Haq
Background: The measurement of left ventricular diastolic dysfunction is important among the impaired glucose tolerance patients. Objectives: The purpose of the present study was to see the echocardiographic characteristics of left ventricular diastolic dysfunction among impaired glucose tolerance patients. Methodology: This cross sectional study was carried out in the Department of Cardiology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2005 to June 2007 for a period of two (02) years. Patients with impaired glucose tolerance (IGT) patients attending Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh and fulfilled selection criteria were included in this study as group A. The apparently healthy persons without cardiovascular disease were taken as group B. All the study subjects underwent 2D and M-mode echocardiography for chamber enlargement, ventricular hypertrophy and ventricular systolic function according to recommendation of American Society of Echocardiography. Result: 2D and M-mode echocardiographic characteristics were compared between groups. Among the parameters, LA size in the group A was 31.18±3.49 mm and in group B was 25.22±4.95 mm which was significantly higher (p<0.01) in the case group. LA size was also compared among left ventricular diastolic dysfunction (LVDD) present and absent group, which was (32.76±4.61 vs 28.79±4.11 mm, p<0.001) significantly higher in the LVDD present group. Conclusion: In conclusion there is a significant differences of echocardiographic characteristics of left ventricular diastolic dysfunction among impaired glucose tolerance patients. Journal of National Institute of Neurosciences Bangladesh, 2020;6(1): 38-42
背景:左室舒张功能障碍的测量在糖耐量受损患者中很重要。目的:本研究的目的是观察糖耐量受损患者左室舒张功能障碍的超声心动图特征。方法:本横断面研究于2005年7月至2007年6月在孟加拉国达卡的Bangabandhu Sheikh Mujib医科大学(BSMMU)心内科进行,为期2年。在孟加拉国达卡的孟加拉国糖尿病、内分泌和代谢疾病研究与康复研究所(BIRDEM)就诊并符合选择标准的糖耐量受损(IGT)患者作为本研究的a组。无心血管疾病的表面健康者作为b组。所有研究对象均行二维和m型超声心动图进行房扩。心室肥厚和心室收缩功能根据美国超声心动图学会的建议。结果:两组间二维和m型超声心动图特征比较。其中,A组LA大小为31.18±3.49 mm, B组LA大小为25.22±4.95 mm,均显著高于病例组(p<0.01)。左室舒张功能不全(LVDD)组与无左室舒张功能不全(LVDD)组的LA大小(32.76±4.61 vs 28.79±4.11 mm, p<0.001)显著高于左室舒张功能不全组。结论:糖耐量受损患者左室舒张功能障碍超声心动图特征存在显著差异。孟加拉国国家神经科学研究所学报,2020;6(1):38-42
{"title":"Echocardiographic Characteristics of Left Ventricular Diastolic Dysfunction among Impaired Glucose Tolerance Patients","authors":"A. Bhuiyan, Z. Sultana, M. Khan, A. M. Rahman, M. R. Ahsan, M. M. Rahmam, K. Hasan, M. Haq","doi":"10.3329/jninb.v6i1.48028","DOIUrl":"https://doi.org/10.3329/jninb.v6i1.48028","url":null,"abstract":"Background: The measurement of left ventricular diastolic dysfunction is important among the impaired glucose tolerance patients. \u0000Objectives: The purpose of the present study was to see the echocardiographic characteristics of left ventricular diastolic dysfunction among impaired glucose tolerance patients. \u0000Methodology: This cross sectional study was carried out in the Department of Cardiology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2005 to June 2007 for a period of two (02) years. Patients with impaired glucose tolerance (IGT) patients attending Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh and fulfilled selection criteria were included in this study as group A. The apparently healthy persons without cardiovascular disease were taken as group B. All the study subjects underwent 2D and M-mode echocardiography for chamber enlargement, ventricular hypertrophy and ventricular systolic function according to recommendation of American Society of Echocardiography. \u0000Result: 2D and M-mode echocardiographic characteristics were compared between groups. Among the parameters, LA size in the group A was 31.18±3.49 mm and in group B was 25.22±4.95 mm which was significantly higher (p<0.01) in the case group. LA size was also compared among left ventricular diastolic dysfunction (LVDD) present and absent group, which was (32.76±4.61 vs 28.79±4.11 mm, p<0.001) significantly higher in the LVDD present group. \u0000Conclusion: In conclusion there is a significant differences of echocardiographic characteristics of left ventricular diastolic dysfunction among impaired glucose tolerance patients. \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(1): 38-42","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82644435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-04DOI: 10.3329/jninb.v6i1.48004
R. Chowdhury, Mohammad Enayet Hussain
Abstract not available Journal of National Institute of Neurosciences Bangladesh, 2020;6(1): 1-2
孟加拉国家神经科学研究所学报,2020;6(1):1-2
{"title":"Clinical Neurophysiology: An Extension of Clinical Examination","authors":"R. Chowdhury, Mohammad Enayet Hussain","doi":"10.3329/jninb.v6i1.48004","DOIUrl":"https://doi.org/10.3329/jninb.v6i1.48004","url":null,"abstract":"Abstract not available \u0000Journal of National Institute of Neurosciences Bangladesh, 2020;6(1): 1-2","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76287848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-07DOI: 10.3329/jninb.v5i2.43024
M. M. H. Chowdhury, N. Sultana, Mir Abu Naim, Towhida Nashrin, L. Nahar
Background: : Cross-bite is one of the most prevalent malocclusion. Objective: This study was an attempt to find out the prevalence of crossbite in Bangladeshi population and its variation with age and gender. Methodology: This cross-sectional study was conducted in the dental unit of Rajshahi Medical College, Rajshahi, Bangladesh from January, 2017 to December, 2018. Patients who were seeking comprehensive orthodontic treatment at the OPD of Rajshahi Medical College Dental Unit, Rajshahi, Bangladesh in between 5 to 35 years of age were diagnosed for cross-bite with diagnostic model. The findings of each cases was recorded in a preformed datasheet and the descriptive analysis was performed. Result: Out of 300 cases 163(54.3%) cases had cross-bite, 90(30%) cases had anterior cross-bite and 109(36.3%) cases had posterior cross bite. Among posterior crossbite 60(20%) had unilateral and 49(16.3%) had bilateral crossbite. Conclusion: Posterior crossbite was more prevalent than anterior crossbite. Cases with Class I molar relation showed more crossbite. Crossbite was more prevalent in cases with congenitally missing teeth Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 167-171
{"title":"Prevalence of Cross Bite among the Orthodontic Patients at a Dental Unit of Bangladesh","authors":"M. M. H. Chowdhury, N. Sultana, Mir Abu Naim, Towhida Nashrin, L. Nahar","doi":"10.3329/jninb.v5i2.43024","DOIUrl":"https://doi.org/10.3329/jninb.v5i2.43024","url":null,"abstract":"Background: : Cross-bite is one of the most prevalent malocclusion. \u0000Objective: This study was an attempt to find out the prevalence of crossbite in Bangladeshi population and its variation with age and gender. \u0000Methodology: This cross-sectional study was conducted in the dental unit of Rajshahi Medical College, Rajshahi, Bangladesh from January, 2017 to December, 2018. Patients who were seeking comprehensive orthodontic treatment at the OPD of Rajshahi Medical College Dental Unit, Rajshahi, Bangladesh in between 5 to 35 years of age were diagnosed for cross-bite with diagnostic model. The findings of each cases was recorded in a preformed datasheet and the descriptive analysis was performed. \u0000Result: Out of 300 cases 163(54.3%) cases had cross-bite, 90(30%) cases had anterior cross-bite and 109(36.3%) cases had posterior cross bite. Among posterior crossbite 60(20%) had unilateral and 49(16.3%) had bilateral crossbite. \u0000Conclusion: Posterior crossbite was more prevalent than anterior crossbite. Cases with Class I molar relation showed more crossbite. Crossbite was more prevalent in cases with congenitally missing teeth \u0000Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 167-171","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78066844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-07DOI: 10.3329/jninb.v5i2.43026
K. Joy, A. Hasan, R. Islam, F. Kalam, M. Kabir, M. Habib, Q. Mohammad
Background: Diabetic polyneuropathy (DPN) has a significant positive correlation with poor glycemic control (HbA1c ≥7%). The clinical, biochemical and electrophysiological parameters of DPN in Bangladeshi citizens have not yet been explored elaborately Objective: The purpose of the study was to detect and categorize status of glycemic control of Bangladeshi people and to analyze its impact on clinical severity of DPN using Toronto Clinical Scoring System (TCSS) and electrophysiological severity by modified Michigan diabetic neuropathy score (MDNS). Methodology: This observational study was carried out on diabetic patients having probable DPN by purposive sampling, attending Neurology OPD of Dhaka Medical College Hospital, Dhaka, Bangladesh and Bangladesh Institute of Research & Rehabilitation in Diabetes, Endocrine & Metabolic Disorder (BIRDEM) Hospital, Dhaka, Bangladesh from July 2014 to June 2016. Clinical parameters were recorded and DPN was graded as “no neuropathy”, “mild”, “moderate” and “severe” neuropathy by the Toronto Clinical Scoring System (TCSS). A standard nerve conduction study was performed on each patient and electrophysiological grading according to modified Michigan diabetic neuropathy score (MDNS) was done. Diabetic status of patients was classified into “controlled” (HbA1c <7.0%) and “uncontrolled” (HbA1c ≥7.0%) groups and HbA1c level and the clinical & electrophysiological severity scores were compared and were analyzed. Results: Mean age of the patients was 57.2±9.37 years. 51.0% cases were males and 49% cases were females. The mean HbA1c in the study population was 7.6±0.94% and 56.0% patients had HbA1c≥ 7% .Motor nerve conduction studies revealed that both CMAP amplitudes and MNCV in the ulnar, peroneal and tibial nerves were reduced significantly in patients of uncontrolled (HbA1c≥7%) DM (p<0.001). Sensory nerve conduction studies revealed significant reduction in SNAP amplitudes of median and ulnar sensory and sural nerves in the uncontrolled group (p<0.001). Electrophysiologically, 65.43% patients had mixed sensory-motor neuropathy (p<0.00001). Clinically severe DPN patients were higher (45.2%) within the uncontrolled (HbA1C ≥7%) group (p<0.00001). Similarly, severity in electrophysiological grading was more in patients with uncontrolled DM (48.8%) (p<0.00001). Conclusions: Neuropathic severity, either clinically or electrophysiologically, was associated with higher values of HbA1c. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 177-184
{"title":"Glycemic Control and Clinico-Electrophysiological Severity of Diabetic Polyneuropathy","authors":"K. Joy, A. Hasan, R. Islam, F. Kalam, M. Kabir, M. Habib, Q. Mohammad","doi":"10.3329/jninb.v5i2.43026","DOIUrl":"https://doi.org/10.3329/jninb.v5i2.43026","url":null,"abstract":"Background: Diabetic polyneuropathy (DPN) has a significant positive correlation with poor glycemic \u0000control (HbA1c ≥7%). The clinical, biochemical and electrophysiological parameters of DPN in Bangladeshi citizens have not yet been explored elaborately \u0000Objective: The purpose of the study was to detect and categorize status of glycemic control of Bangladeshi people and to analyze its impact on clinical severity of DPN using Toronto Clinical Scoring System (TCSS) and electrophysiological severity by modified Michigan diabetic neuropathy score (MDNS). \u0000Methodology: This observational study was carried out on diabetic patients having probable DPN by purposive sampling, attending Neurology OPD of Dhaka Medical College Hospital, Dhaka, Bangladesh and Bangladesh Institute of Research & Rehabilitation in Diabetes, Endocrine & Metabolic Disorder (BIRDEM) Hospital, Dhaka, Bangladesh from July 2014 to June 2016. Clinical parameters were recorded and DPN was graded as “no neuropathy”, “mild”, “moderate” and “severe” neuropathy by the Toronto Clinical Scoring System (TCSS). A standard nerve conduction study was performed on each patient and electrophysiological grading according to modified Michigan diabetic neuropathy score (MDNS) was done. Diabetic status of patients was classified into “controlled” (HbA1c <7.0%) and “uncontrolled” (HbA1c ≥7.0%) groups and HbA1c level and the clinical & electrophysiological severity scores were compared and were analyzed. \u0000Results: Mean age of the patients was 57.2±9.37 years. 51.0% cases were males and 49% cases were females. The mean HbA1c in the study population was 7.6±0.94% and 56.0% patients had HbA1c≥ 7% .Motor nerve conduction studies revealed that both CMAP amplitudes and MNCV in the ulnar, peroneal and tibial nerves were reduced significantly in patients of uncontrolled (HbA1c≥7%) DM (p<0.001). Sensory nerve conduction studies revealed significant reduction in SNAP amplitudes of median and ulnar sensory and sural nerves in the uncontrolled group (p<0.001). Electrophysiologically, 65.43% patients had mixed sensory-motor neuropathy (p<0.00001). Clinically severe DPN patients were higher (45.2%) within the uncontrolled (HbA1C ≥7%) group (p<0.00001). Similarly, severity in electrophysiological grading was more in patients with uncontrolled DM (48.8%) (p<0.00001). \u0000Conclusions: Neuropathic severity, either clinically or electrophysiologically, was associated with higher values of HbA1c. \u0000Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 177-184","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89704641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-07DOI: 10.3329/jninb.v5i2.43011
M. E. Hussain, Afm Al Masum Khan, Abdulwaheed Adebola Yusuf, Ferdous Mian, N. Islam, B. Debnath, A. Hoque, B. Alam, Q. Mohammad, R. Chowdhury
Background: SSPE is a late complication of measles and is fatal in most cases. Objectives: The purpose of the study was to observe the clinico-demographic, investigation and outcome profiles of SSPE patients. Methodology: This prospective cohort study was conducted in the Department of Neurophysiology at National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from September 2014 to August 2017. Patients of SSPE who were diagnosed by Dyken's Criteria were selected as study population. Details socio-demographic, clinical profiles, investigations and outcome were recorded. The outcome was assessed from the time of first onset of the symptoms till closing of the study. Results: The mean age of the study population was 14.3±4.209 years with the male predominance (73.5%). Majority were from rural area (70.6%) and were of low socio-economic condition (52.9%). The mean age of onset of disease was 13.6±4.30 years. History of previous measles infection was reported in 13(38.2%) cases among which 12(92.3%) cases were vaccinated. The mean age of measles infection was 17.0±15.44 months. The time of first symptom of SSPE from primary measles infection was 11.50±4.80 years. Recurrent fall (47.1%) and myoclonic jerks (17.6%) were the most frequent initial symptoms of the patient. Cognitive decline was observed in 28(82.4%) cases. EEG background was slow in 23(67.6%) patients and periodic burst was observed in all (100.0%) cases. Anti-measles antibody in CSF was positive in all cases. MRI was abnormal in 7(25.9%) cases out of 27 cases. Twelve (35.3%) patients died, 18(52.9%) were alive and 4(11.8%) were lost to follow up when the study was closed. Conclusion: Early aged male from lower socioeconomic condition are found to be suffering from SSPE. Recurrent fall is the commonest initial presentation. Spontaneous recovery can occur in very few patients. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 97-100
{"title":"Clinico-demographic, Investigation and Outcomes Profiles of Subacute Sclerosing Panencephalitis (SSPE) Patients at A Referral Neurology Hospital in Bangladesh","authors":"M. E. Hussain, Afm Al Masum Khan, Abdulwaheed Adebola Yusuf, Ferdous Mian, N. Islam, B. Debnath, A. Hoque, B. Alam, Q. Mohammad, R. Chowdhury","doi":"10.3329/jninb.v5i2.43011","DOIUrl":"https://doi.org/10.3329/jninb.v5i2.43011","url":null,"abstract":"Background: SSPE is a late complication of measles and is fatal in most cases. \u0000Objectives: The purpose of the study was to observe the clinico-demographic, investigation and outcome profiles of SSPE patients. \u0000Methodology: This prospective cohort study was conducted in the Department of Neurophysiology at National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from September 2014 to August 2017. Patients of SSPE who were diagnosed by Dyken's Criteria were selected as study population. Details socio-demographic, clinical profiles, investigations and outcome were recorded. The outcome was assessed from the time of first onset of the symptoms till closing of the study. \u0000Results: The mean age of the study population was 14.3±4.209 years with the male predominance (73.5%). Majority were from rural area (70.6%) and were of low socio-economic condition (52.9%). The mean age of onset of disease was 13.6±4.30 years. History of previous measles infection was reported in 13(38.2%) cases among which 12(92.3%) cases were vaccinated. The mean age of measles infection was 17.0±15.44 months. The time of first symptom of SSPE from primary measles infection was 11.50±4.80 years. Recurrent fall (47.1%) and myoclonic jerks (17.6%) were the most frequent initial symptoms of the patient. Cognitive decline was observed in 28(82.4%) cases. EEG background was slow in 23(67.6%) patients and periodic burst was observed in all (100.0%) cases. Anti-measles antibody in CSF was positive in all cases. MRI was abnormal in 7(25.9%) cases out of 27 cases. Twelve (35.3%) patients died, 18(52.9%) were alive and 4(11.8%) were lost to follow up when the study was closed. \u0000Conclusion: Early aged male from lower socioeconomic condition are found to be suffering from SSPE. Recurrent fall is the commonest initial presentation. Spontaneous recovery can occur in very few patients. \u0000Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 97-100","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90636377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-07DOI: 10.3329/jninb.v5i2.43018
Saydur Rahman, Syed Ariful Islam, Jobayer Hossain, M. S. Arefin, Imrul Islam, Sharmin Ara Begum, Shofina Sultana Shompa, Akm Akhtaruzzaman
Background: Platelet Rich Plasma (PRP) is increasingly applied in clinical practice to treat knee degenerative pathology. Both PRP and hyaluronic acid (HA) have been extensively used to improve lubrication, modulate inflammation and modify the catabolic micro-environment of the joint. Objective: This study was aimed to evaluate the potential synergistic effects of PRP in combination with hyaluronic acid in primary knee osteoarthritis. Methodology: This randomized control trial was carried out on adult patients with primary knee osteoarthritis who attended the Pain Clinic of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, during the period of September 2015 to August 2017. The patients were randomly assigned to one of the two groups designated as group P (control group) who were only treated with PRP and group PH (experimental group) who were treated with the combination of PRP and hyaluronic acid. After providing the allocated treatment, all patients were undergone follow-up examination at 1st week, 1st month and 3rd month for pain improvement by VAS scale and for functional improvement by International Knee Documentation Committee (IKDC) score. Results: A total number of 34 patients were recruited for this study. Visual analogue score 1st month (5.85±0.83) and 3rd month (3.01±0.12) follow up showed statistically significant difference among two group (p=0.001). Inter group comparison showed that, mean VAS score of group PH (3.01±0.12) decreased more than Group P (4.01±1.01). In case of functional improvement, group PH also showed statistically better improvement during 1st month (45.76±3.25) and 3rd month (62.06±5.37) follow up than Group P. Conclusion: In conclusion articular platelet rich plasma in combination with hyaluronic acid provide better pain relief and improvement of functional status than PRP therapy alone in primary knee osteoarthritis. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 137-142
{"title":"Effects of Platelet Rich Plasma in Combination with Hyaluronic Acid in the Treatment of Primary Knee Osteoarthritis","authors":"Saydur Rahman, Syed Ariful Islam, Jobayer Hossain, M. S. Arefin, Imrul Islam, Sharmin Ara Begum, Shofina Sultana Shompa, Akm Akhtaruzzaman","doi":"10.3329/jninb.v5i2.43018","DOIUrl":"https://doi.org/10.3329/jninb.v5i2.43018","url":null,"abstract":"Background: Platelet Rich Plasma (PRP) is increasingly applied in clinical practice to treat knee degenerative pathology. Both PRP and hyaluronic acid (HA) have been extensively used to improve lubrication, modulate inflammation and modify the catabolic micro-environment of the joint. \u0000Objective: This study was aimed to evaluate the potential synergistic effects of PRP in combination with hyaluronic acid in primary knee osteoarthritis. \u0000Methodology: This randomized control trial was carried out on adult patients with primary knee osteoarthritis who attended the Pain Clinic of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, during the period of September 2015 to August 2017. The patients were randomly assigned to one of the two groups designated as group P (control group) who were only treated with PRP and group PH (experimental group) who were treated with the combination of PRP and hyaluronic acid. After providing the allocated treatment, all patients were undergone follow-up examination at 1st week, 1st month and 3rd month for pain improvement by VAS scale and for functional improvement by International Knee Documentation Committee (IKDC) score. \u0000Results: A total number of 34 patients were recruited for this study. Visual analogue score 1st month (5.85±0.83) and 3rd month (3.01±0.12) follow up showed statistically significant difference among two group (p=0.001). Inter group comparison showed that, mean VAS score of group PH (3.01±0.12) decreased more than Group P (4.01±1.01). In case of functional improvement, group PH also showed statistically better improvement during 1st month (45.76±3.25) and 3rd month (62.06±5.37) follow up than Group P. \u0000Conclusion: In conclusion articular platelet rich plasma in combination with hyaluronic acid provide better pain relief and improvement of functional status than PRP therapy alone in primary knee osteoarthritis. \u0000Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 137-142","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88178211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-07DOI: 10.3329/jninb.v5i2.43016
A. Momin, Enayet Ul Islam, F. Sharmin, M. E. Hussain, A. Hoque
Background: Different non-motor neurological complaints are reported among the Parkinson’s disease patients. Objective: The purpose of the present study was to see the non-motor neurological complaints of Parkinson’s disease patients. Methodology: This cross-sectional study was carried out in the in-patient and out-patient Department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka from July 2012 to December 2013 for a period of one and half year. All patients with Parkinson’s disease who were admitted under department of Medicine and Neurology and also who visited out-patient department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka were included as study population. Patients who were diagnosed according to Brain Bank clinical criteria for diagnosis of Parkinson’s disease were included in this study. The non-motor neurological complaints were recorded. Result: This study was conducted in Sir Salimullah Medical College and Mitford Hospital with a view to see the non-motor neurological complaints of Parkinson’s disease. The mean age was found 69.15±10.08 years. Most of the patients had a combination of non-motor symptoms and among them more than two third (66.7%) of the patients had cognitive impairment; furthermore more than half (53.8%) of the patients had sleep disturbance. One fourth (25.0%) of patients had sensory, sleep and cognitive disorder; however, 9(22.5%) patients had sleep and cognitive disorder. Conclusion: In conclusion majority Parkinson’s disease patients are suffering from cognitive impairment followed by sleep disturbances. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 123-126
{"title":"Variation of Non-Motor Neurological Symptoms of Parkinson’s disease Patients","authors":"A. Momin, Enayet Ul Islam, F. Sharmin, M. E. Hussain, A. Hoque","doi":"10.3329/jninb.v5i2.43016","DOIUrl":"https://doi.org/10.3329/jninb.v5i2.43016","url":null,"abstract":"Background: Different non-motor neurological complaints are reported among the Parkinson’s disease patients. \u0000Objective: The purpose of the present study was to see the non-motor neurological complaints of Parkinson’s disease patients. \u0000Methodology: This cross-sectional study was carried out in the in-patient and out-patient Department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka from July 2012 to December 2013 for a period of one and half year. All patients with Parkinson’s disease who were admitted under department of Medicine and Neurology and also who visited out-patient department of Medicine and Neurology of Sir Salimullah Medical College and Mitford Hospital, Dhaka were included as study population. Patients who were diagnosed according to Brain Bank clinical criteria for diagnosis of Parkinson’s disease were included in this study. The non-motor neurological complaints were recorded. \u0000Result: This study was conducted in Sir Salimullah Medical College and Mitford Hospital with a view to see the non-motor neurological complaints of Parkinson’s disease. The mean age was found 69.15±10.08 years. Most of the patients had a combination of non-motor symptoms and among them more than two third (66.7%) of the patients had cognitive impairment; furthermore more than half (53.8%) of the patients had sleep disturbance. One fourth (25.0%) of patients had sensory, sleep and cognitive disorder; however, 9(22.5%) patients had sleep and cognitive disorder. \u0000Conclusion: In conclusion majority Parkinson’s disease patients are suffering from cognitive impairment followed by sleep disturbances. \u0000Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 123-126","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79919692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-07DOI: 10.3329/jninb.v5i2.43027
S. Sultana, A. Sharif, N. Begum, S. Parveen, W. Begum, M. Haque
Background: Cataract surgery is very important for the correction of visual acuity among the patients. Objective: The purpose of the present study was to assess the uncorrected visual acuity in small incision cataract surgery (SICS) with PCIOL than conventional method of ECCE with PCIOL implantation. Methodology: This cross-sectional study was conducted at National Institute of Ophthalmology, Dhaka, Bangladesh from January 1999 to December 2000 for a period of two (02) years. Patients with senile cataract were selected for study. A comparative study of changes in postoperative visual outcome and refractive status during post-operative follow up period up to 2 months were observed and documented between two groups of patients, one with suture less nonphaco SICS with PCIOL another with conventional ECCE with PCIOL. All the cataract surgery were done by the same surgeon, and in same place. All the patients were examined carefully both pre and post-operatively. For the purpose of recording, a proforma was made that includes particulars of the patient, complete history, general examination, ocular examination, relevant investigations, operation note, perioperative complications, post-operative follow-up, pre and post-operative visual acuity with keratometric reading. Result: A total of 60 eyes of cataract patients were included in the study of which 30 eyes of cataract patients were randomly selected for suture less nonphaco SICS with PCIOL and 30 eyes of cataract patients were for conventional ECCE with PCIOL.Mean age distribution (58.83±5.55 and 58.77±6.56) was similar in both groups. The unaided vision in both SICS & ECCE group at different postoperative intervals was reported. At day7 and month 1 postoperatively the result appears highly significant between the two groups. At day 1 and month 2 also shows the significant result between the 2 groups. The best corrected visual acuity in SICS and ECCE group at different postoperative intervals was measured. At day 7 and month 1 postoperatively the result appears highly significant between the two groups. At day 1 and month 2 also shows the significant result between the 2 groups.In SICS group out of 30 patients, 7(23.3%) cases acquired unaided vision 6/9 at day 1, 10(33.3%) patients at day 7,14(46.6%)patients at month 1 and 15(49.9%) patients at month 2. On the other hand in ECCE group no patient was found with vision ≥6/9 at day 1 and only one patient with vision ≥6/9 at day 7.At month 1 there were 5(16.6%) patients, and at month 2 there were 9(29.9%)patients with vision ≥6/9. Nearly 50.0% patients of SICS group achieve unaided vision of ≥6/9 within the follow up period of 02 months. Conclusion: In conclusion Uncorrected visual acuity in SICS cases were better than that of ECCE cases with sutures. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 185-190
{"title":"Comparison of Nonphaco small incision Cataract Surgery with Conventional Method: An Observational Study","authors":"S. Sultana, A. Sharif, N. Begum, S. Parveen, W. Begum, M. Haque","doi":"10.3329/jninb.v5i2.43027","DOIUrl":"https://doi.org/10.3329/jninb.v5i2.43027","url":null,"abstract":"Background: Cataract surgery is very important for the correction of visual acuity among the patients. \u0000Objective: The purpose of the present study was to assess the uncorrected visual acuity in small incision cataract surgery (SICS) with PCIOL than conventional method of ECCE with PCIOL implantation. \u0000Methodology: This cross-sectional study was conducted at National Institute of Ophthalmology, Dhaka, Bangladesh from January 1999 to December 2000 for a period of two (02) years. Patients with senile cataract were selected for study. A comparative study of changes in postoperative visual outcome and refractive status during post-operative follow up period up to 2 months were observed and documented between two groups of patients, one with suture less nonphaco SICS with PCIOL another with conventional ECCE with PCIOL. All the cataract surgery were done by the same surgeon, and in same place. All the patients were examined carefully both pre and post-operatively. For the purpose of recording, a proforma was made that includes particulars of the patient, complete history, general examination, ocular examination, relevant investigations, operation note, perioperative complications, post-operative follow-up, pre and post-operative visual acuity with keratometric reading. \u0000Result: A total of 60 eyes of cataract patients were included in the study of which 30 eyes of cataract patients were randomly selected for suture less nonphaco SICS with PCIOL and 30 eyes of cataract patients were for conventional ECCE with PCIOL.Mean age distribution (58.83±5.55 and 58.77±6.56) was similar in both groups. The unaided vision in both SICS & ECCE group at different postoperative intervals was reported. At day7 and month 1 postoperatively the result appears highly significant between the two groups. At day 1 and month 2 also shows the significant result between the 2 groups. The best corrected visual acuity in SICS and ECCE group at different postoperative intervals was measured. At day 7 and month 1 postoperatively the result appears highly significant between the two groups. At day 1 and month 2 also shows the significant result between the 2 groups.In SICS group out of 30 patients, 7(23.3%) cases acquired unaided vision 6/9 at day 1, 10(33.3%) patients at day 7,14(46.6%)patients at month 1 and 15(49.9%) patients at month 2. On the other hand in ECCE group no patient was found with vision ≥6/9 at day 1 and only one patient with vision ≥6/9 at day 7.At month 1 there were 5(16.6%) patients, and at month 2 there were 9(29.9%)patients with vision ≥6/9. Nearly 50.0% patients of SICS group achieve unaided vision of ≥6/9 within the follow up period of 02 months. \u0000Conclusion: In conclusion Uncorrected visual acuity in SICS cases were better than that of ECCE cases with sutures. \u0000Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 185-190","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82640291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-07DOI: 10.3329/jninb.v5i2.43021
B. K. Das, Mohiuddin Ahmed, I. Haider, Uday Kumar Goswami, Mohammad Kamorzzaman
Background: Odontogenic tumor can occur among children with the variation of different age and gender. Objective: The purpose of the present study was to see the age and gender distribution of odontogenic benigntumor originated in the oro-facial region among children. Methodology: This cross-sectional study was studied in the department of Oral and Maxillofacial Surgery at Dhaka Dental College and Hospital, Dhaka, Bangladesh from January 2010 to June 2012 for a period of 2 and half year.Children below 18 years of age irrespective of gender, histopathologically diagnosed case of odontogenic tumours were included in this study. Diagnosis of those tumour was done by history, clinical findings and histopathological or cytopathological examination. The clinical, histopathological or FNAC findings were analysed. Result: Among the total benign lesions 30 were odontogenic. In the total odontogenic tumour patients 9 cases were odontogenic keratocyst; 9 cases were ameloblastoma; 5 cases were ameloblastic fibroma; 3 cases were odontogenic myxoma and 4 cases were odontogenic fibroma.Among the patients with odontogenic tumours 15 were less than 10 years old and 15 were 10 to 18 years old. Odontogenic Keratocyst was the most common benign tumour (20.0%) cases among less than 10 years of age group. In 10 to 18 years of age group the most common reported benign tumour was Ameloblastoma (21.6%). Male and female ratio was 1.7:1. Among male Ameloblastoma was the most commonly detected benign tumour (17.1%). Among female childrenodontogenic keratocyst was the most reported tumour (18.8%). Conclusion: In conclusion the most common odontogenic benign tumour are odontogenic keratocyst and ameloblastoma. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 152-155
{"title":"Age and Gender Distribution of Benign Paediatric Odontogenic Tumor: Experience of 30 Cases in Dhaka City","authors":"B. K. Das, Mohiuddin Ahmed, I. Haider, Uday Kumar Goswami, Mohammad Kamorzzaman","doi":"10.3329/jninb.v5i2.43021","DOIUrl":"https://doi.org/10.3329/jninb.v5i2.43021","url":null,"abstract":"Background: Odontogenic tumor can occur among children with the variation of different age and gender. \u0000Objective: The purpose of the present study was to see the age and gender distribution of odontogenic benigntumor originated in the oro-facial region among children. \u0000Methodology: This cross-sectional study was studied in the department of Oral and Maxillofacial Surgery at Dhaka Dental College and Hospital, Dhaka, Bangladesh from January 2010 to June 2012 for a period of 2 and half year.Children below 18 years of age irrespective of gender, histopathologically diagnosed case of odontogenic tumours were included in this study. Diagnosis of those tumour was done by history, clinical findings and histopathological or cytopathological examination. The clinical, histopathological or FNAC findings were analysed. \u0000Result: Among the total benign lesions 30 were odontogenic. In the total odontogenic tumour patients 9 cases were odontogenic keratocyst; 9 cases were ameloblastoma; 5 cases were ameloblastic fibroma; 3 cases were odontogenic myxoma and 4 cases were odontogenic fibroma.Among the patients with odontogenic tumours 15 were less than 10 years old and 15 were 10 to 18 years old. Odontogenic Keratocyst was the most common benign tumour (20.0%) cases among less than 10 years of age group. In 10 to 18 years of age group the most common reported benign tumour was Ameloblastoma (21.6%). Male and female ratio was 1.7:1. Among male Ameloblastoma was the most commonly detected benign tumour (17.1%). Among female childrenodontogenic keratocyst was the most reported tumour (18.8%). \u0000Conclusion: In conclusion the most common odontogenic benign tumour are odontogenic keratocyst and ameloblastoma. \u0000Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 152-155","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78674942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}