Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63745
Jalal Uddin Mohammad Rumi, M. A. Haleem, Md Bashir Ahammed, S. Arifin, Md. Rakibul Islam, F. Chowdhury
Background: Detection of aneurysms among spontaneous subarachnoid haemorrhagic patients is a crucial issue for management. Objectives: The purpose of the present study was to compare the findings of 3D-computed tomographic angiography with digital subtraction angiography for detection of aneurysms among spontaneous subarachnoid haemorrhagic patients. Methodology: This comparative cross-sectional study was carried out in the Department of Neurosurgery and Cath Lab of Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh in collaboration with private diagnostic centre from September 2013 to February 2015 for a period of six (06) months. Adult patients diagnosed as a case of spontaneous SAH based on clinical features and confirmed by plain CT evidence of subarachnoid blood were included as study cases. Then both CTA and DSA were done in order to detect the cause of bleeding and make a treatment planning. All spiral CTAs were performed on a helical CT-Scan. Four vessels DSA were performed via a femoral approach in DMCH Cath Lab. Result: A total number of 37 patients presented with spontaneous subarachnoid haemorrhage were recruited for this study. CT Angiogram revealed aneurysm in 30(81.08%) patients. AVM found in 02(05.41%) patients and in 5(13.51%) patients CTA was negative for any abnormality. DSA of 37 patients revealed aneurysm in 32(86.49%) patients, AVM in 02(05.41%) patients and negative findings in 03(8.11%) patients. In CT Angiogram 25(67.57%) patients had single aneurysm. In DSA, 27(72.97%) patients had single aneurysm. The mean of the size of the aneurysms in CTA and DSA were in 6.70±3.04 mm and 6.75±2.94 mm (p>0.05). The mean of the neck width of the aneurysms in CTA and DSA were 3.86±2.06 mm and 3.41±1.67 mm (p>0.05). All aneurysm detected in CTA were also revealed in DSA. Conclusion: In conclusion the size, neck width and the location of aneurysm are detected in CTA and DSA equally without any statistical significant difference. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):121-125
背景:自发性蛛网膜下腔出血患者动脉瘤的检测是治疗的关键问题。目的:本研究的目的是比较3d计算机断层血管造影和数字减影血管造影对自发性蛛网膜下腔出血患者动脉瘤的检测结果。方法:这项比较横断面研究于2013年9月至2015年2月在孟加拉国达卡达卡医学院医院(DMCH)神经外科和Cath实验室与私人诊断中心合作进行，为期6(06)个月。根据临床特征诊断为自发性SAH并经蛛网膜下腔血CT平扫证实的成年患者纳入研究病例。然后进行CTA和DSA检查，以便发现出血原因并制定治疗方案。所有螺旋cta均在螺旋ct扫描上进行。在DMCH Cath实验室经股骨入路行4条血管DSA。结果:本研究共招募了37例自发性蛛网膜下腔出血患者。CT血管造影显示动脉瘤30例(81.08%)。02例(05.41%)患者发现AVM, 5例(13.51%)患者CTA未发现任何异常。37例患者中，DSA显示动脉瘤32例(86.49%)，AVM 02例(05.41%)，阴性03例(8.11%)。CT血管造影中有25例(67.57%)为单动脉瘤。在DSA中，27例(72.97%)患者为单动脉瘤。动脉瘤在CTA和DSA上的平均大小分别为6.70±3.04 mm和6.75±2.94 mm (p>0.05)。CTA和DSA检查动脉瘤颈宽的平均值分别为3.86±2.06 mm和3.41±1.67 mm (p>0.05)。所有在CTA中发现的动脉瘤在DSA中也能被发现。结论:综上所述，CTA与DSA对动脉瘤大小、颈宽及位置的检测结果相同，差异无统计学意义。孟加拉国国家神经科学研究所杂志，2022年7月;8(2):121-125
{"title":"Comparison of 3D-Computed Tomographic Angiography with Digital Subtraction Angiography for Detection of aneurysms among Spontaneous Subarachnoid Haemorrhagic Patients","authors":"Jalal Uddin Mohammad Rumi, M. A. Haleem, Md Bashir Ahammed, S. Arifin, Md. Rakibul Islam, F. Chowdhury","doi":"10.3329/jninb.v8i2.63745","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63745","url":null,"abstract":"Background: Detection of aneurysms among spontaneous subarachnoid haemorrhagic patients is a crucial issue for management. \u0000Objectives: The purpose of the present study was to compare the findings of 3D-computed tomographic angiography with digital subtraction angiography for detection of aneurysms among spontaneous subarachnoid haemorrhagic patients. \u0000Methodology: This comparative cross-sectional study was carried out in the Department of Neurosurgery and Cath Lab of Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh in collaboration with private diagnostic centre from September 2013 to February 2015 for a period of six (06) months. Adult patients diagnosed as a case of spontaneous SAH based on clinical features and confirmed by plain CT evidence of subarachnoid blood were included as study cases. Then both CTA and DSA were done in order to detect the cause of bleeding and make a treatment planning. All spiral CTAs were performed on a helical CT-Scan. Four vessels DSA were performed via a femoral approach in DMCH Cath Lab. \u0000Result: A total number of 37 patients presented with spontaneous subarachnoid haemorrhage were recruited for this study. CT Angiogram revealed aneurysm in 30(81.08%) patients. AVM found in 02(05.41%) patients and in 5(13.51%) patients CTA was negative for any abnormality. DSA of 37 patients revealed aneurysm in 32(86.49%) patients, AVM in 02(05.41%) patients and negative findings in 03(8.11%) patients. In CT Angiogram 25(67.57%) patients had single aneurysm. In DSA, 27(72.97%) patients had single aneurysm. The mean of the size of the aneurysms in CTA and DSA were in 6.70±3.04 mm and 6.75±2.94 mm (p>0.05). The mean of the neck width of the aneurysms in CTA and DSA were 3.86±2.06 mm and 3.41±1.67 mm (p>0.05). All aneurysm detected in CTA were also revealed in DSA. \u0000Conclusion: In conclusion the size, neck width and the location of aneurysm are detected in CTA and DSA equally without any statistical significant difference. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):121-125","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85072184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63777
Md Abdullah Yusuf
Abstract not available Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):103-104
孟加拉国国家神经科学研究所杂志，2022年7月;8(2):103-104
{"title":"Importance of Neurovirology Diagnostic Laboratory at Referral Neuroscience Hospital in Bangladesh","authors":"Md Abdullah Yusuf","doi":"10.3329/jninb.v8i2.63777","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63777","url":null,"abstract":"Abstract not available \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):103-104","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"111 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79215636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63747
Most Samsun Nahar Sumi, Razia Sultana, S. Khatun, Mohammad Shah Jahan Chowdhury, M. E. Hussain, R. Chowdhury, N. Saha
Background: Infantile spasms (epileptic spasm) is an epileptic encephalopathy with unique clinical and electrographic features, which affects children mostly in the middle of the first year of life. Objective: The aim of this study was to evaluate the clinical and electroencephalographic profile and short-term outcome in infantile spasm. Methodology: This was a randomized controlled trial study done in Department of Pediatric Neurology, National Institute of Neuroscience & Hospital, Dhaka, Bangladesh. The patient of infantile spasm aged 2 months to 2 years were enrolled in the study from June 2017 to May 2018. With parent’s written informed consent, they were randomized into two groups, 25 in each. One group got ACTH only and another group got both ACTH and vigabatrin. Detailed history including seizure pattern was taken. EEG was done before and after2 -3 weeks of starting treatment. They were followed up at 8, 15, 43 days. Results: The mean age of onset of seizure (mean ±SD) was 7.24±4.13 (2 to 19) month on hormonal therapy and 6.84±5.89 (2 to 22) month on combination therapy. Most patient had history of perinatal birth asphyxia, developmental delay, seizure pattern was flexor spasm and EEG pattern were predominantly classical hypsarrhythmia in both groups. After treatment cessation of spasms occurred between 14 to 42 days in 72.0% in combination therapy and 44% in hormonal therapy (P value=0.045). EEG became normal in 60.0% and 32.0% patients in combination and hormonal therapy respectively (P value =0.047). Conclusion: In conclusion combination therapy of ACTH hormone plus vigabatrin has better than ACTH therapy alone in cessation of clinical spasms and electroencephalographic remission. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):130-135
{"title":"Clinical and Electroencephalographic Pattern and Short-Term Outcome to Treatment in Infantile Spasm: A Randomized Controlled Trial","authors":"Most Samsun Nahar Sumi, Razia Sultana, S. Khatun, Mohammad Shah Jahan Chowdhury, M. E. Hussain, R. Chowdhury, N. Saha","doi":"10.3329/jninb.v8i2.63747","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63747","url":null,"abstract":"Background: Infantile spasms (epileptic spasm) is an epileptic encephalopathy with unique clinical and electrographic features, which affects children mostly in the middle of the first year of life. \u0000Objective: The aim of this study was to evaluate the clinical and electroencephalographic profile and short-term outcome in infantile spasm. \u0000Methodology: This was a randomized controlled trial study done in Department of Pediatric Neurology, National Institute of Neuroscience & Hospital, Dhaka, Bangladesh. The patient of infantile spasm aged 2 months to 2 years were enrolled in the study from June 2017 to May 2018. With parent’s written informed consent, they were randomized into two groups, 25 in each. One group got ACTH only and another group got both ACTH and vigabatrin. Detailed history including seizure pattern was taken. EEG was done before and after2 -3 weeks of starting treatment. They were followed up at 8, 15, 43 days. \u0000Results: The mean age of onset of seizure (mean ±SD) was 7.24±4.13 (2 to 19) month on hormonal therapy and 6.84±5.89 (2 to 22) month on combination therapy. Most patient had history of perinatal birth asphyxia, developmental delay, seizure pattern was flexor spasm and EEG pattern were predominantly classical hypsarrhythmia in both groups. After treatment cessation of spasms occurred between 14 to 42 days in 72.0% in combination therapy and 44% in hormonal therapy (P value=0.045). EEG became normal in 60.0% and 32.0% patients in combination and hormonal therapy respectively (P value =0.047). \u0000Conclusion: In conclusion combination therapy of ACTH hormone plus vigabatrin has better than ACTH therapy alone in cessation of clinical spasms and electroencephalographic remission. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):130-135","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85035269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63752
Rabeya Sultana, Niilufa Parvin, P. Deb, S. Munshi, S. Tabassum
Background: Several plasma proteins are proposed as biomarkers for acute HEV infected patients, but have not been validated among pregnant Bangladeshi women infected with HEV. Objective: In this present study, levels of interlukin-10 (IL-10), tumor necrosis factor α (TNF-α) and complement-3 (C3) were measured among HEV infected pregnant women and were compared with pregnant and HEV infected women. Methodology: This comparative cross-sectional study was conducted among the pregnant women who were admitted to the Department of Medicine, Department of Obstetrics & Gynecology, and Department of Hepatology of Dhaka Medical College Hospital (DMCH) and Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh for 1 year period. The study population included acute HEV infected pregnant women (HEV-P), healthy pregnant women (HPC) and HEV-infected non-pregnant women (HEV-NP) of the same age group. Interlukin-10 (IL-10), Tumor necrosis factor α (TNF-α) and complement 3(C3) levels were quantified by enzyme linked immunosorbent assay (ELISA) and turbidometry, respectively. Result: A total number of 81 women were recruited for this study of which 31 cases were acute HEV infected pregnant women (HEV-P); 25 cases were healthy pregnant women (HPC) and 25 cases were HEV infected non-pregnant women (HEV-NP) of the same age group. The mean levels with SD of the C3 level showed significant difference (P; 0.05) between groups of HEV-P (67.73±38.24 mg/dl), HEV-NP (147.9±22.28 mg/dl) and HPC (182.6±17.49 mg/dl). Though plasma TNF-α did not show any significant change (P; .05) in any of the groups, the IL-10 level was elevated significantly (p; 0.05) in HEV infected pregnant patients (0.187±0.3 ng/ml) then the non-pregnant HEV patients (0.027 + .08 ng/ml) and pregnant women group (0.012±0.04 ng/ml). Conclusion: In conclusion, increased levels of C3 and IL-10 observed in HEV infected pregnant women. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):157-161
{"title":"Comparison of Interlukin-10, Tumor Necrosis Factor-α and Complement-3 Levels among Bangladeshi Pregnant Women with or without Hepatitis E Virus Infection","authors":"Rabeya Sultana, Niilufa Parvin, P. Deb, S. Munshi, S. Tabassum","doi":"10.3329/jninb.v8i2.63752","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63752","url":null,"abstract":"Background: Several plasma proteins are proposed as biomarkers for acute HEV infected patients, but have not been validated among pregnant Bangladeshi women infected with HEV. \u0000Objective: In this present study, levels of interlukin-10 (IL-10), tumor necrosis factor α (TNF-α) and complement-3 (C3) were measured among HEV infected pregnant women and were compared with pregnant and HEV infected women. \u0000Methodology: This comparative cross-sectional study was conducted among the pregnant women who were admitted to the Department of Medicine, Department of Obstetrics & Gynecology, and Department of Hepatology of Dhaka Medical College Hospital (DMCH) and Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh for 1 year period. The study population included acute HEV infected pregnant women (HEV-P), healthy pregnant women (HPC) and HEV-infected non-pregnant women (HEV-NP) of the same age group. Interlukin-10 (IL-10), Tumor necrosis factor α (TNF-α) and complement 3(C3) levels were quantified by enzyme linked immunosorbent assay (ELISA) and turbidometry, respectively. \u0000Result: A total number of 81 women were recruited for this study of which 31 cases were acute HEV infected pregnant women (HEV-P); 25 cases were healthy pregnant women (HPC) and 25 cases were HEV infected non-pregnant women (HEV-NP) of the same age group. The mean levels with SD of the C3 level showed significant difference (P; 0.05) between groups of HEV-P (67.73±38.24 mg/dl), HEV-NP (147.9±22.28 mg/dl) and HPC (182.6±17.49 mg/dl). Though plasma TNF-α did not show any significant change (P; .05) in any of the groups, the IL-10 level was elevated significantly (p; 0.05) in HEV infected pregnant patients (0.187±0.3 ng/ml) then the non-pregnant HEV patients (0.027 + .08 ng/ml) and pregnant women group (0.012±0.04 ng/ml). \u0000Conclusion: In conclusion, increased levels of C3 and IL-10 observed in HEV infected pregnant women. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):157-161","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84727362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63748
Gm Hafizur Rahman, Amanullah Bin Siddiq, Al Asma Ul Taslima, Hossain Muhammad Mustafijur Rahman, F. Ahmed
Background: Many stroke patients develop swallowing difficulty and require nasogastric feeding for the maintenance of nutrition. Objectives: The purpose of the present study was to evaluate the complications of nasogastric tube feeding practice on stroke patients. Methodology: This cross-sectional study was conducted from April 2014 to September 2014 in the Department of Medicine at Dhaka Medical College Hospital, Dhaka, Bangladesh. Adult patients aged between 18 to 70 years with stroke was enrolled in the study. The diagnosis of stroke was established by the clinical presentation and neuroimaging. Patients requiring nasogastric tube feeding was included in the study and were systematically examined for any complications related to use of nasogastric tube. Their caregivers were also thoroughly interviewed using a standard pre formed questionnaire regarding any complications as well. Results: Of the 100 patients studied, most common age group for stroke was 51 to 60 years (53.0%). Male to female ratio was 2.22:1. In this study population, 63.0% patients had ischaemic stroke; 26.0% had haemorrhagic stroke; 9.0% population had subarachnoid haemorrhage. The most common indication for NG feeding was difficulty in swallowing (39.0%). Other common indications were semi-consciousness (26%), unconsciousness (22.0%), inability to maintain feed (10.0%). Around 71.0% of the patients had complications from NG tube feeding. Out of them, 53.0% of the patients had nasal irritation, 40.0% patients developed aspiration pneumonia. 38.0% of the patients developed diarrhea, 53.0% had tube blockage. 43.0% of the patients had electrolyte imbalance and tube displacement, 18.0% of the patients were malnourished. Conclusion: In conclusion nasogastric tube feeding is associated with various complications which can increase the morbidities in stroke patients. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):136-142
{"title":"Complications Associated with Nasogastric Tube Feeding among Stroke Patients at a Tertiary Hospital in Dhaka City","authors":"Gm Hafizur Rahman, Amanullah Bin Siddiq, Al Asma Ul Taslima, Hossain Muhammad Mustafijur Rahman, F. Ahmed","doi":"10.3329/jninb.v8i2.63748","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63748","url":null,"abstract":"Background: Many stroke patients develop swallowing difficulty and require nasogastric feeding for the maintenance of nutrition. \u0000Objectives: The purpose of the present study was to evaluate the complications of nasogastric tube feeding practice on stroke patients. \u0000Methodology: This cross-sectional study was conducted from April 2014 to September 2014 in the Department of Medicine at Dhaka Medical College Hospital, Dhaka, Bangladesh. Adult patients aged between 18 to 70 years with stroke was enrolled in the study. The diagnosis of stroke was established by the clinical presentation and neuroimaging. Patients requiring nasogastric tube feeding was included in the study and were systematically examined for any complications related to use of nasogastric tube. Their caregivers were also thoroughly interviewed using a standard pre formed questionnaire regarding any complications as well. \u0000Results: Of the 100 patients studied, most common age group for stroke was 51 to 60 years (53.0%). Male to female ratio was 2.22:1. In this study population, 63.0% patients had ischaemic stroke; 26.0% had haemorrhagic stroke; 9.0% population had subarachnoid haemorrhage. The most common indication for NG feeding was difficulty in swallowing (39.0%). Other common indications were semi-consciousness (26%), unconsciousness (22.0%), inability to maintain feed (10.0%). Around 71.0% of the patients had complications from NG tube feeding. Out of them, 53.0% of the patients had nasal irritation, 40.0% patients developed aspiration pneumonia. 38.0% of the patients developed diarrhea, 53.0% had tube blockage. 43.0% of the patients had electrolyte imbalance and tube displacement, 18.0% of the patients were malnourished. \u0000Conclusion: In conclusion nasogastric tube feeding is associated with various complications which can increase the morbidities in stroke patients. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):136-142","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87746050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63774
Mohammad Gani, M. A. Hossain, Taskin Nazmin, M. Hasan, Mohammad Rakibul Islam Babu
Background: The distribution of dental abnormalities specially missing tooth is common among the cleft palate & lip patient wherefore the aim of this study was to evaluate the prevalence of hypodontia in case of Bangladeshi cleft population. Objective: The purpose of the present study was to compare the congenital tooth deficiencies seen in permanent dentition in individuals with unilateral cleft lip and palate (UCLP) to non-cleft individuals with Angle Class I malocclusion. Methodology: This is a retrospective case control study between UCLP and Angle Class l malocclusion patients. This study was done on OPG films taken before treatment from 80 patients who applied for orthodontic treatment. 40 individuals with UCLP between the ages of 12 - 16 years were compared with the 40 individuals with Angle Class I malocclusion with no CLP aged between 12 - 16 years. Individuals with UCLP; 21 clefts were on the left side and 19 clefts were on the right side. The congenitally deficient teeth were recorded from the OPG films. In this study, third molars were not included in the evaluation. Results: In this study, no differences were found in regard to the gender of the patient. The left side of the patients was affected substantially more than the right side. The frequency of the missing upper lateral incisors in the cleft side of the patients was significantly higher than the non-cleft side. Therapists of cleft patients need to be aware of the high variety of numerical alterations, as this is important for therapy planning and the applied treatment. Conclusion: The management of dental anomalies, which can easily be detected by careful inspection of routine orthodontic diagnostic records, should be taken into consideration in treatment planning of individuals with a cleft. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):198-201
{"title":"Comparison of Missing Permanent Tooth in Bangladeshi Unilateral Cleft Lip and Palate to those without Cleft Lip and Palate","authors":"Mohammad Gani, M. A. Hossain, Taskin Nazmin, M. Hasan, Mohammad Rakibul Islam Babu","doi":"10.3329/jninb.v8i2.63774","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63774","url":null,"abstract":"Background: The distribution of dental abnormalities specially missing tooth is common among the cleft palate & lip patient wherefore the aim of this study was to evaluate the prevalence of hypodontia in case of Bangladeshi cleft population. \u0000Objective: The purpose of the present study was to compare the congenital tooth deficiencies seen in permanent dentition in individuals with unilateral cleft lip and palate (UCLP) to non-cleft individuals with Angle Class I malocclusion. \u0000Methodology: This is a retrospective case control study between UCLP and Angle Class l malocclusion patients. This study was done on OPG films taken before treatment from 80 patients who applied for orthodontic treatment. 40 individuals with UCLP between the ages of 12 - 16 years were compared with the 40 individuals with Angle Class I malocclusion with no CLP aged between 12 - 16 years. Individuals with UCLP; 21 clefts were on the left side and 19 clefts were on the right side. The congenitally deficient teeth were recorded from the OPG films. In this study, third molars were not included in the evaluation. \u0000Results: In this study, no differences were found in regard to the gender of the patient. The left side of the patients was affected substantially more than the right side. The frequency of the missing upper lateral incisors in the cleft side of the patients was significantly higher than the non-cleft side. Therapists of cleft patients need to be aware of the high variety of numerical alterations, as this is important for therapy planning and the applied treatment. \u0000Conclusion: The management of dental anomalies, which can easily be detected by careful inspection of routine orthodontic diagnostic records, should be taken into consideration in treatment planning of individuals with a cleft. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):198-201","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79982924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63750
Md Faruq Amin Talukder, Md Nazrul Islam, Eusha Ahmad Fidalillah Ansary, Md. Abdullah Al Mamun, Md Bellal Hossain, R. Naznin, Md. Nizam Uddin Chowdhury
Background: Serological status of thyroid hormones is important among chronic kidney disease patients. Objective: The purpose of the present study was to see the status of thyroid hormones among chronic kidney disease patients. Methodology: This cross-sectional study was done From January 2013 to December 2013 in the Department of Nephrology, Dhaka Medical College Hospital. A total of 50 diagnosed cases of adult male with different stages of CKD (CKD stage 3, 4, 5 and 5D) patients along with age-matched 51 healthy individuals were included. Serum Thyroid hormone T3 done by [1251] RIA kit, T4 done by T4 [1251] RIA kit, TSH level done by Turbo TSH [1251] IRMA kit. Result: A total number of 101 patients were recruited for this study of which 51 cases were in the group A and the rest of the 50 cases were in the group B. The mean serum T3 level was found 1.85±0.7 nmoL/L in group A and 2.79±0.55 nmoL/L in group B (p<0.05) which indicated that low serum T3 level was significantly associated with CKD. The mean serum T4 level was found 104.65±34.9 nmol/L in group A and 138.8±31.5 nmol/L in group B (p<0.05). Serum TSH level of the study patients showed that the mean serum TSH level was found 4.23±4.6 mIU/L in group A and 2.06±2.5mIU/L in group B (p<0.05). Conclusion: In conclusion the mean with SD of serum level of T3, T4 and TSH were significantly associated with chronic kidney disease. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):147-151
{"title":"Evaluation of Thyroid Function Tests among Chronic Kidney Disease Patients attended at a Tertiary Care Hospital in Dhaka City","authors":"Md Faruq Amin Talukder, Md Nazrul Islam, Eusha Ahmad Fidalillah Ansary, Md. Abdullah Al Mamun, Md Bellal Hossain, R. Naznin, Md. Nizam Uddin Chowdhury","doi":"10.3329/jninb.v8i2.63750","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63750","url":null,"abstract":"Background: Serological status of thyroid hormones is important among chronic kidney disease patients. \u0000Objective: The purpose of the present study was to see the status of thyroid hormones among chronic kidney disease patients. \u0000Methodology: This cross-sectional study was done From January 2013 to December 2013 in the Department of Nephrology, Dhaka Medical College Hospital. A total of 50 diagnosed cases of adult male with different stages of CKD (CKD stage 3, 4, 5 and 5D) patients along with age-matched 51 healthy individuals were included. Serum Thyroid hormone T3 done by [1251] RIA kit, T4 done by T4 [1251] RIA kit, TSH level done by Turbo TSH [1251] IRMA kit. \u0000Result: A total number of 101 patients were recruited for this study of which 51 cases were in the group A and the rest of the 50 cases were in the group B. The mean serum T3 level was found 1.85±0.7 nmoL/L in group A and 2.79±0.55 nmoL/L in group B (p<0.05) which indicated that low serum T3 level was significantly associated with CKD. The mean serum T4 level was found 104.65±34.9 nmol/L in group A and 138.8±31.5 nmol/L in group B (p<0.05). Serum TSH level of the study patients showed that the mean serum TSH level was found 4.23±4.6 mIU/L in group A and 2.06±2.5mIU/L in group B (p<0.05). \u0000Conclusion: In conclusion the mean with SD of serum level of T3, T4 and TSH were significantly associated with chronic kidney disease. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):147-151","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73952455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63751
Rabeya Parvin, S. Nargis, Most Afroza Sarkar, Khaledun Nessa, Runa Parvin, R. Khanam
Background: Management of early pregnancy loss is very crucial for the safety of women. Objective: The purpose of the present study was to see the safety and efficacy of misoprostol for the management of early pregnancy loss. Methodology: This non-randomized clinical trial was conducted in the Department of Obstetrics and Gynaecology in Shaheed Ziaur Rahman Medical College Hospital, Bogra, Bangladesh from January 2007 to December 2007 for a period of 12 months. Women with early pregnancy loss who were fulfilling the selection criteria were selected as the study population during the study period. On admission all women were received a vaginal administration of 800 μg misoprostol by digital insertion into the posterior fornix through a speculum (4 tablets of 200 μg misoprostol). The interval between administration of misoprostol and expulsion of product of conception was recorded. After 7 days (8th day) they were instructed to come to the hospital to see the completeness of expulsion of product of conception by ultrasonography. If sonography shows incomplete expulsion then surgical evacuation was done. Every woman were advised to come for follow-up on 15th day. Results: A total of 200 women with first-trimester pregnancy loss were non-randomly assigned to give treatment with misoprostol. The mean with the SD of the study population was 24.95±4.17 years. In most cases expulsion occurred within 24 hours of application of misoprostol, 142(71.0%) cases completed expulsion within 48 hours, 168(84.0%) cases within 7 days, 170(85.0%) cases out of 200 cases completed expulsion occurred. Complete evacuation after the first dose was in 142(71.0%) cases and remained incomplete was 58(29.0%) cases. After administration of the second dose (85.0%) complete evacuation occurred and 30(15.0%) cases remained complete that needed surgical evacuation. Analysis was reveled statistically significant (P<0.05). Vaginal misoprostol treatment appeared to be well tolerated. Only few percent shows mild side effects. About 190(95.0%) cases required no blood transfusion. Conclusion: In conclusion the efficacy of misoprostol for the management of early pregnancy loss gives a good results with minimum adverse events. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):152-156
{"title":"Safety and Efficacy of Misoprostol for the Management of Early Pregnancy Loss: A Non-Randomized Clinical Trial","authors":"Rabeya Parvin, S. Nargis, Most Afroza Sarkar, Khaledun Nessa, Runa Parvin, R. Khanam","doi":"10.3329/jninb.v8i2.63751","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63751","url":null,"abstract":"Background: Management of early pregnancy loss is very crucial for the safety of women. \u0000Objective: The purpose of the present study was to see the safety and efficacy of misoprostol for the management of early pregnancy loss. \u0000Methodology: This non-randomized clinical trial was conducted in the Department of Obstetrics and Gynaecology in Shaheed Ziaur Rahman Medical College Hospital, Bogra, Bangladesh from January 2007 to December 2007 for a period of 12 months. Women with early pregnancy loss who were fulfilling the selection criteria were selected as the study population during the study period. On admission all women were received a vaginal administration of 800 μg misoprostol by digital insertion into the posterior fornix through a speculum (4 tablets of 200 μg misoprostol). The interval between administration of misoprostol and expulsion of product of conception was recorded. After 7 days (8th day) they were instructed to come to the hospital to see the completeness of expulsion of product of conception by ultrasonography. If sonography shows incomplete expulsion then surgical evacuation was done. Every woman were advised to come for follow-up on 15th day. Results: A total of 200 women with first-trimester pregnancy loss were non-randomly assigned to give treatment with misoprostol. The mean with the SD of the study population was 24.95±4.17 years. In most cases expulsion occurred within 24 hours of application of misoprostol, 142(71.0%) cases completed expulsion within 48 hours, 168(84.0%) cases within 7 days, 170(85.0%) cases out of 200 cases completed expulsion occurred. Complete evacuation after the first dose was in 142(71.0%) cases and remained incomplete was 58(29.0%) cases. After administration of the second dose (85.0%) complete evacuation occurred and 30(15.0%) cases remained complete that needed surgical evacuation. Analysis was reveled statistically significant (P<0.05). Vaginal misoprostol treatment appeared to be well tolerated. Only few percent shows mild side effects. About 190(95.0%) cases required no blood transfusion. Conclusion: In conclusion the efficacy of misoprostol for the management of early pregnancy loss gives a good results with minimum adverse events. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):152-156","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76896639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63749
A. Bhuiyan, K. Hasan, Partha Pratim Saha, Sayeda Sadia Fathema, Najmul Huda Biplob
Background: Patients with right ventricular infarction is a critical condition and may cause adverse cardiac events. Objective: The purpose of the present study was to compare the in-hospital complications among patients with right ventricular infarction based on TIMI risk score. Methodology: This prospective observational study was conducted in the Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh from May 2007 to April 2008 for a period of one year. All the patients who were admitted into the coronary care unit of NICVD with acute inferior myocardial infarction with or without anterior myocardial infarction were selected as study population. Inclusion Criteria were patients admitted in CCU (NICVD) with acute inferior myocardial infarction with right ventricular infarction. Patients were categorized into two groups according to the extent of TIMI risk score. Patients with low TIMI risk score (0 to 3) were included in Group I and patients with high TIMI risk-score (4 to 14) were include in group II. Patients were followed up in their hospital stay to see the incidence of major cardiac events. Results: A total number of 60 patients with right ventricular infarction of which 30 consecutive patients with low TIMI risk score (0 to 3) were in Group I and 30 consecutive patients with high TIMI risk score (4 to 14) were in Group II. In-hospital mortality was 18.3% in the study populations and it was significantly higher in group II (33.3%) than group (3.3%). The next most common complication is cardiogenic shock followed by complete heart block, Cardiac arrest, VT and 2nd degree heart block. Conclusion: In conclusion the in-hospital mortality in the study populations is significantly higher in group II than group I Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):143-146
{"title":"Comparison of In-Hospital Complications among Patients with Right Ventricular Infarction","authors":"A. Bhuiyan, K. Hasan, Partha Pratim Saha, Sayeda Sadia Fathema, Najmul Huda Biplob","doi":"10.3329/jninb.v8i2.63749","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63749","url":null,"abstract":"Background: Patients with right ventricular infarction is a critical condition and may cause adverse cardiac events. \u0000Objective: The purpose of the present study was to compare the in-hospital complications among patients with right ventricular infarction based on TIMI risk score. \u0000Methodology: This prospective observational study was conducted in the Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh from May 2007 to April 2008 for a period of one year. All the patients who were admitted into the coronary care unit of NICVD with acute inferior myocardial infarction with or without anterior myocardial infarction were selected as study population. Inclusion Criteria were patients admitted in CCU (NICVD) with acute inferior myocardial infarction with right ventricular infarction. Patients were categorized into two groups according to the extent of TIMI risk score. Patients with low TIMI risk score (0 to 3) were included in Group I and patients with high TIMI risk-score (4 to 14) were include in group II. Patients were followed up in their hospital stay to see the incidence of major cardiac events. \u0000Results: A total number of 60 patients with right ventricular infarction of which 30 consecutive patients with low TIMI risk score (0 to 3) were in Group I and 30 consecutive patients with high TIMI risk score (4 to 14) were in Group II. In-hospital mortality was 18.3% in the study populations and it was significantly higher in group II (33.3%) than group (3.3%). The next most common complication is cardiogenic shock followed by complete heart block, Cardiac arrest, VT and 2nd degree heart block. \u0000Conclusion: In conclusion the in-hospital mortality in the study populations is significantly higher in group II than group I \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):143-146","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75570435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-15DOI: 10.3329/jninb.v8i2.63770
Sherajum Munira, N. Fatema, Jannatul Ferdous Runa, Nasim Mahmood
Background: Teenagers face greater risk of pregnancy than the woman in their adulthood. Objective: The purpose of the present study was to see the maternal outcomes of women presented with teenager pregnancy. Methodology: This cross-sectional study was performed in the Department of Obstetrics and Gynecology at Kurmitola General Hospital, Dhaka, Bangladesh for a period of six months from March 2019 to September 2019. The teenage mothers with the age group of 13 to 19 completed years at delivery who were admitted to the Department of Obstetrics and Gynecology were included in this study. On admission, diagnosis was established by history, presenting complaints, physical examination, per-abdominal examination and per-vaginal examination. Complications during pregnancy and labour, mode of delivery, post-partum complications and perinatal outcome were noted. Results: A total number of 100 teenage mothers were recruited for this study. During this study period, 74.0% mothers were aged 18 to 19 years. About 52.0% cases of teenage mothers were suffered from various complications during pregnancy and labor and among them, anemia was in 21.15% cases; UTI was in 3.84% cases; PE was in 17.31% cases; eclampsia was in 3.84% cases; PROM was in 15.38% cases; CPD was in 5.76% cases; prolonged labor was in 93.34% cases; obstructed labor 6.66% cases and preterm labor 15.4% cases. Their modes of delivery were vaginal delivery 63%, caesarean delivery 39%. Among them, indications of caesarean delivery were PROM with Fd 30.77% Gross IUGR with FD 12.82% cases prolonged labor 10.26%, obstructed labor 2.56%, CPD 7.69%, eclampsia 5.13% cases. 57% of teenage mothers suffered from postpartum complications. Among them, PPH was 28.07% cases, inadequate lactation 10.53% cases, Post spinal headache 10.53% cases and wound infection 10.53% cases. Conclusion: In conclusion the most common maternal complication are anemia, UTI, PE, eclampsia, PROM, CPD, prolonged labor, obstructed labor and preterm labor. Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):185-188
{"title":"Maternal Outcome among Women Presented with Teenage Pregnancy attended at a Tertiary Care Hospital in Dhaka City","authors":"Sherajum Munira, N. Fatema, Jannatul Ferdous Runa, Nasim Mahmood","doi":"10.3329/jninb.v8i2.63770","DOIUrl":"https://doi.org/10.3329/jninb.v8i2.63770","url":null,"abstract":"Background: Teenagers face greater risk of pregnancy than the woman in their adulthood. \u0000Objective: The purpose of the present study was to see the maternal outcomes of women presented with teenager pregnancy. \u0000Methodology: This cross-sectional study was performed in the Department of Obstetrics and Gynecology at Kurmitola General Hospital, Dhaka, Bangladesh for a period of six months from March 2019 to September 2019. The teenage mothers with the age group of 13 to 19 completed years at delivery who were admitted to the Department of Obstetrics and Gynecology were included in this study. On admission, diagnosis was established by history, presenting complaints, physical examination, per-abdominal examination and per-vaginal examination. Complications during pregnancy and labour, mode of delivery, post-partum complications and perinatal outcome were noted. \u0000Results: A total number of 100 teenage mothers were recruited for this study. During this study period, 74.0% mothers were aged 18 to 19 years. About 52.0% cases of teenage mothers were suffered from various complications during pregnancy and labor and among them, anemia was in 21.15% cases; UTI was in 3.84% cases; PE was in 17.31% cases; eclampsia was in 3.84% cases; PROM was in 15.38% cases; CPD was in 5.76% cases; prolonged labor was in 93.34% cases; obstructed labor 6.66% cases and preterm labor 15.4% cases. Their modes of delivery were vaginal delivery 63%, caesarean delivery 39%. Among them, indications of caesarean delivery were PROM with Fd 30.77% Gross IUGR with FD 12.82% cases prolonged labor 10.26%, obstructed labor 2.56%, CPD 7.69%, eclampsia 5.13% cases. 57% of teenage mothers suffered from postpartum complications. Among them, PPH was 28.07% cases, inadequate lactation 10.53% cases, Post spinal headache 10.53% cases and wound infection 10.53% cases. \u0000Conclusion: In conclusion the most common maternal complication are anemia, UTI, PE, eclampsia, PROM, CPD, prolonged labor, obstructed labor and preterm labor. \u0000Journal of National Institute of Neurosciences Bangladesh, July 2022;8(2):185-188","PeriodicalId":16732,"journal":{"name":"Journal of National Institute of Neurosciences Bangladesh","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79777591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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