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Phenylpropanoids Comprise a Multitude of Plant-Specialized Metabolites and Cell Wall Components 苯丙素包括多种植物特化代谢物和细胞壁成分
Pub Date : 2021-01-01 DOI: 10.1016/b978-0-12-818631-2.00018-0
H. Heldt, B. Piechulla
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引用次数: 2
Chemically Produced Plants Developed and Controlled by Physiological Reactions in the Tissue 由组织中的生理反应发展和控制的化学生产植物
Pub Date : 2021-01-01 DOI: 10.35248/2329-9029.21.9.263
G. Pope
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引用次数: 0
Lipids Are Membrane Constituents and Function as Carbon Stores 脂质是膜成分,具有碳储存的功能
Pub Date : 2021-01-01 DOI: 10.1016/B978-0-12-384986-1.00015-6
H. Heldt, B. Piechulla
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引用次数: 10
Biotechnology Alters Plants to Meet the Requirements of Agriculture, Nutrition, and Industry 生物技术改变植物以满足农业、营养和工业的需要
Pub Date : 2021-01-01 DOI: 10.1016/b978-0-12-818631-2.00022-2
H. Heldt, B. Piechulla
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引用次数: 0
Leaf Cells Consist of Several Metabolic Compartments 叶细胞由几个代谢区室组成
Pub Date : 2021-01-01 DOI: 10.1016/b978-0-12-818631-2.00001-5
H. Heldt, B. Piechulla
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引用次数: 0
Identification of Antihypertensive Mechanisms ofFicus deltoidea kunstleri; in Spontaneously Hypertensive Rats Using Metabolomics 山茱萸抗高血压作用机制的研究利用代谢组学研究自发性高血压大鼠
Pub Date : 2021-01-01 DOI: 10.35248/2329-9029.21.9.261
Harbinder Singh, N. A. Azis, M. S. A. Kamal, Ahmed Mediani, R. Agarwal, Zurain Radjeni, N. Ismail
Blood pressure lowering effect of Ficus deltoidea kunstleri (FDK) has been associated with changes in the Renin-Angiotensin-Aldosterone System (RAAS) and endothelial function in Spontaneously Hypertensive Rats (SHR). Whether it also involves other systems is unclear. This study therefore screened for other potential BP lowering mechanisms in FDK-treated SHR based on urine metabolite profile obtained using 1H-NMR spectrometry and multivariate data analysis. Male SHR were administered orally, either 0.5 mL of distilled water (control), or 1000 mg.kg-1 body weight of FDK or 10 mg.kg-1 body weight of losartan once daily for 4 weeks. BP was measured weekly and 24-hr urine was collected using metabolic chambers at the end of the 4th week. Animals were then euthanised and blood was collected for estimation of total anti-oxidant capacity TAC. Kidneys were harvested for antioxidant enzyme gene expression studies. BP in FDK- and losartan-treated SHR was significantly lower, whereas serum TAC was significantly higher than those in the controls. Orthogonal partial least square analysis indicated that FDK-treated SHR were separated from controls by the presence of a larger number of ketone body and amino acid metabolism intermediates. Superoxide dismutase-2, catalase and fork head box gene expressions were higher in kidneys of FDK-treated SHR than those in the controls. It appears that apart from RAAS, the BP lowering effect of standardized aqueous-ethanolic extract of leaves of FDK in SHR is also associated with increased TAC, antioxidant enzyme expressions and probably also involves multiple metabolic pathways, including those involving ketone bodies, amino acids and energy metabolism
无花果(FDK)的降压作用与自发性高血压大鼠(SHR)肾素-血管紧张素-醛固酮系统(RAAS)和内皮功能的改变有关。目前尚不清楚它是否也涉及其他系统。因此,本研究基于1H-NMR光谱和多变量数据分析获得的尿液代谢物谱,筛选fdk治疗SHR的其他潜在降压机制。男性SHR被口服0.5 mL蒸馏水(对照)或1000 mg。kg-1体重的FDK或10毫克。Kg-1体重氯沙坦每日1次,连用4周。每周测量血压,并在第4周结束时使用代谢室收集24小时尿液。然后对动物实施安乐死,并收集血液以估计总抗氧化能力TAC。采集肾脏用于抗氧化酶基因表达研究。FDK和氯沙坦治疗的SHR组血压显著低于对照组,而血清TAC显著高于对照组。正交偏最小二乘分析表明,fdk处理的SHR与对照相比存在较多的酮体和氨基酸代谢中间体。fdk处理的SHR肾脏中超氧化物歧化酶-2、过氧化氢酶和叉头盒基因的表达高于对照组。可见,除RAAS外,FDK叶片标准化水乙醇提取物在SHR中的降压作用还与TAC、抗氧化酶表达增加有关,可能涉及酮体、氨基酸和能量代谢等多种代谢途径
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引用次数: 0
Proteins are Enormous Biomolecules that Binds with Other Proteins for Interfaces 蛋白质是一种巨大的生物分子,它与其他蛋白质结合形成界面
Pub Date : 2021-01-01 DOI: 10.35248/2329-9029.21.9.267
Alger Robins
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引用次数: 0
Phytochemicals: Bioactive Nutrient Plant Chemicals Desirable to Health Benefits 植物化学物质:有益健康的生物活性营养植物化学物质
Pub Date : 2021-01-01 DOI: 10.35248/2329-9029.21.9.266
A. Safar
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引用次数: 0
Multiple Signals Regulate the Growth and Development of Plant Organs and Enable Their Adaptation to Environmental Conditions 多种信号调节植物器官的生长发育,使其适应环境条件
Pub Date : 2021-01-01 DOI: 10.1016/B978-012088391-2/50020-1
H. Heldt, B. Piechulla
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引用次数: 1
A Plant Cell Has Three Different Genomes 一个植物细胞有三个不同的基因组
Pub Date : 2021-01-01 DOI: 10.1016/B978-012088391-2/50021-3
H. Heldt, B. Piechulla
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引用次数: 0
期刊
Journal of Plant Biochemistry & Physiology
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