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Longitudinal Estimation of Adequate Physical Activity Levels to Reduce the Risk of Alzheimer's Disease and Other Dementias in Older Adults With Mild Cognitive Impairment. 适当的身体活动水平降低轻度认知障碍老年人阿尔茨海默病和其他痴呆症风险的纵向估计
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-10-07 Print Date: 2026-01-01 DOI: 10.1123/jpah.2025-0355
Jungjoo Lee, Junhyoung Kim, Kangeun Lee

Background: Although previous studies have identified a positive relationship between physical activity (PA) participation and cognitive function in older adults, further research is needed to determine the level of PA necessary to significantly reduce the risk of Alzheimer's disease and related dementias (AD/ADRD), particularly among older adults with mild cognitive impairment.

Methods: This study used Health and Retirement Study data from 2012 to 2020 (n = 9714 Index = 5) and employed the generalized estimating equations to estimate the odds ratios (OR) of AD/ADRD across various PA levels. Covariates such as age, sex, education, and baseline cognitive function in 2012 were included in the regression model.

Results: Individuals with a PA level of 2.80 experienced a 4.6% reduction in the odds of developing AD/ADRD (B = -0.046, OR = 0.954, 95% CI, 0.946-0.964). Similar significant effects were observed at PA levels of 2.60, 2.40, and 2.20, with ORs of 0.962, 0.967, and 0.970, respectively, all within 95% CI. These findings indicate that maintaining a PA level between 2.20 and 2.80 is significantly associated with a reduced risk of AD/ADRD. Lower PA levels such as 2.00 (OR = 0.974, P = .09) and 1.80 (OR = 0.983, P = .06) showed nonsignificant trends toward risk reduction.

Conclusion: Engaging in PA (eg, walking, exercise) more than twice per week significantly reduces the risk of AD/ADRD, whereas less frequent activity showed no statistically significant benefit.

背景:尽管先前的研究已经确定老年人体力活动(PA)参与与认知功能之间存在正相关关系,但需要进一步的研究来确定显著降低阿尔茨海默病和相关痴呆(AD/ADRD)风险所需的PA水平,特别是在轻度认知障碍的老年人中。方法:本研究使用2012 - 2020年健康与退休研究数据(n = 9714 Index = 5),采用广义估计方程估计不同PA水平AD/ADRD的比值比(OR)。回归模型中纳入了年龄、性别、教育程度和2012年基线认知功能等协变量。结果:PA水平为2.80的个体发生AD/ADRD的几率降低4.6% (B = -0.046, OR = 0.954, 95% CI, 0.946-0.964)。在PA水平为2.60、2.40和2.20时观察到类似的显著效应,or分别为0.962、0.967和0.970,均在95% CI范围内。这些发现表明,将PA水平维持在2.20至2.80之间与降低AD/ADRD风险显著相关。较低的PA水平如2.00 (OR = 0.974, P = 0.09)和1.80 (OR = 0.983, P = 0.06)显示风险降低的趋势不显著。结论:每周进行两次以上的PA(如散步、运动)可显著降低AD/ADRD的风险,而频率较低的活动则没有统计学意义上的显著益处。
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引用次数: 0
Exercising With Others, Motivation, and 1-Year Maintenance of Exercise Behavior Among Workers. 与他人一起运动,动机,以及工人运动行为的1年维持。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-10-06 Print Date: 2026-01-01 DOI: 10.1123/jpah.2025-0404
Kazuhiro Harada, Shuhei Izawa, Nanako Nakamura-Taira, Toru Yoshikawa, Rie Akamatsu, Hiroki Ikeda, Tomohide Kubo

Background: Maintaining exercise behavior is important for health. Although exercising with others may be an effective strategy for maintaining this, the association between exercising with others and the maintenance of it as well as the mediators of this association remain unconfirmed. The present study examined whether exercising with others was longitudinally and positively associated with 1-year maintenance of exercise behavior, and this association was mediated by exercise motivation among workers.

Methods: This study used data of an online survey-based longitudinal cohort study on 2819 Japanese workers who performed exercise at baseline and responded to a 1-year follow-up survey. This study analyzed 1-year follow-up data of participation in exercise; baseline and 1-year follow-up data of weekly exercise time; and baseline data of exercising with others, exercise motivation, and demographic factors. Participation in exercise (model 1) and weekly exercise time (model 2) after 1 year were indices of 1-year maintenance of exercise behavior.

Results: Adjusting for demographic factors, path analyses showed that exercising with others at baseline indirectly and significantly predicted 1-year maintenance of exercise behavior, mediated by exercise motivation and weekly exercise time at baseline (standardized total associations, 0.07 in model 1 and 0.18 in model 2; standardized indirect associations, 0.06 in model 1 and 0.18 in model 2).

Conclusions: This study found that exercising with others was indirectly and positively associated with 1-year maintenance of exercise behavior, mediated by exercise motivation. Encouraging participation with others may be effective in supporting motivation and maintaining exercise behavior.

背景:保持锻炼行为对健康很重要。尽管与他人一起锻炼可能是保持这种状态的有效策略,但与他人一起锻炼和保持这种状态之间的联系以及这种联系的中介因素仍未得到证实。本研究考察了与他人一起运动是否与1年的运动行为维持呈纵向正相关,并且这种关联是由工人的运动动机介导的。方法:本研究采用一项基于在线调查的纵向队列研究的数据,对2819名日本工人进行了基线运动,并进行了为期1年的随访调查。本研究分析了参与运动的1年随访数据;每周运动时间基线及1年随访数据;以及与他人一起锻炼的基线数据,锻炼动机和人口因素。1年后的运动参与(模型1)和每周运动时间(模型2)是运动行为维持1年的指标。结果:调整人口统计学因素后,路径分析显示,在基线时与他人一起运动间接且显著地预测运动行为的1年维持,运动动机和每周运动时间在基线时起中介作用(标准化总关联,模型1为0.07,模型2为0.18;标准化间接关联,模型1为0.06,模型2为0.18)。结论:本研究发现,在运动动机的介导下,与他人一起运动与1年的运动行为维持存在间接正相关。鼓励与他人一起参与可能对支持动机和保持锻炼行为有效。
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引用次数: 0
Walk the Vote: Why Democracy Is Important for Promoting Physical Activity Worldwide. 投票:为什么民主对促进全球体育活动很重要。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-10-06 Print Date: 2025-12-01 DOI: 10.1123/jpah.2025-0672
Rodrigo Siqueira Reis
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引用次数: 0
Leveraging Technology to Revolutionize Physical Activity Measurement, Surveillance, and Interventions. 利用技术革新身体活动测量、监测和干预。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-10-01 DOI: 10.1123/jpah.2025-0664
Jacqueline L Mair, Elroy J Aguiar
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引用次数: 0
Association Between the Quality of Public Open Spaces and Their Use for Physical Activity in a Northern City in Uruguay. 乌拉圭北部城市公共开放空间质量与其用于体育活动之间的关系。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-09-30 Print Date: 2026-01-01 DOI: 10.1123/jpah.2025-0048
Sofia Fernandez-Gimenez, Enrique Pintos-Toledo, Rogério César Fermino, Pedro R Olivares, Javier Brazo-Sayavera

Background: Built environments are excellent places/opportunities for sports and recreational practice. However, research on this topic is scarce and unclear in Latin America, especially in Uruguay. This study aimed to analyze the features of resources for sport and recreational physical activity and their association with use in the city of Rivera, Uruguay.

Methods: This observational, cross-sectional study analyzed all available public open spaces (POS) from Rivera city in Uruguay the Physical Activity Resource Assessment checklist to evaluate the presence and quality of resources, and the System for Observation of Play and Recreation in Communities to evaluate the use. Each space was visited 9 times: mornings, afternoons, and evenings on 2 nonconsecutive weekdays and weekend days. A negative binomial regression model was used to analyze the association between POS quality and their use.

Results: Twenty-nine POS were assessed, the squares (58.1%) and sports facilities (22.6%) were the most frequent of resource. A total of 7920 scans were performed in 88 target areas; 808 users were observed, and the highest frequency of use was identified in men on the weekdays (66.4%) and on the weekend (66.7%). Was observed a positive and significant association between the features (P = .028), incivilities (P = .042), and total quality (P = .001) with the number, but there was no association between the amenities (P = .155) and the number users.

Conclusion: Our findings provide relevant information at the local level and suggest promoting intervention policies that help maintain renovated and accessible POS for the physical activity, sports, and outdoor recreation.

背景:人造环境是运动和娱乐实践的绝佳场所/机会。然而,在拉丁美洲,特别是乌拉圭,对这一主题的研究很少,也不清楚。本研究旨在分析乌拉圭里维拉市体育和休闲体育活动资源的特征及其与使用的关系。方法:本观察性横断面研究分析了乌拉圭里维拉市所有可用的公共开放空间(POS),使用体育活动资源评估清单来评估资源的存在和质量,并使用社区游戏和娱乐观察系统来评估其使用情况。每个空间在两个非连续工作日和周末的上午、下午和晚上参观了9次。采用负二项回归模型分析POS质量与使用之间的关系。结果:共有29个POS被评估,其中广场(58.1%)和体育设施(22.6%)是最常见的资源。共对88个靶区进行了7920次扫描;808名用户中,男性使用频率最高的是在工作日(66.4%)和周末(66.7%)。特征(P = 0.028)、不文明程度(P = 0.042)和总体素质(P = 0.001)与用户数量呈正相关,而便利程度(P = 0.155)与用户数量无显著相关。结论:本研究结果在地方层面上提供了相关信息,并建议促进干预政策,以帮助维护翻新和可访问的体力活动,运动和户外娱乐POS。
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引用次数: 0
Physical Activity, Mentorship, and Mental Health in Adolescents Living in Washington, DC: Teens Run DC. 生活在华盛顿特区的青少年的体育活动、指导和心理健康:青少年管理华盛顿特区。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-09-29 Print Date: 2026-01-01 DOI: 10.1123/jpah.2025-0276
Tim O'Neal, Loretta DiPietro, Olga A Price

Background: Mental health is a serious concern among US adolescents. We examined the role of a combined running/mentorship program, Teens Run DC (TRDC), on self-reported indicators of mental health in high-school students (N = 291) living in Washington, DC.

Methods: The TRDC program was offered in 10 high schools across 7 DC wards between 2010 and 2018. We used a quasi-experimental design within each school to determine the relation between dose of the TRDC program, and indicators of depression, and social connectedness in students who did and did not participate in the program. Data were collected at the beginning and end of each school year, using the Center for Epidemiological Studies Depression in Children scale and the Hemingway Social Connectedness scale. Mixed-effect regression modeling examined the dose-response relationship between participation dose and mental health scores.

Results: High school students who completed at least 2 years of TRDC lowered their Center for Epidemiological Studies Depression in Children scale score by 6 points (β = -5.9; 95% CI, -10.7 to -1.0) and had a 69% lower odds of developing symptoms of clinical depression (odds ratios = 0.31; 95% CI, 0.23 to 0.42), compared with students receiving less than one year. Similarly, students with 2 or more years of TRDC increased their overall Hemingway Social Connectedness score by 8 points (β = 7.9; 95% CI, 0.65 to 15.1), relative to those with less than one year of exposure. The benefits of TRDC were especially pronounced in female students.

Conclusion: These findings indicate that a running/mentoring program has substantial mental health benefits for high school students and this is particularly so for teenage girls.

背景:心理健康是美国青少年的一个严重问题。我们研究了一个联合的跑步/指导计划,青少年跑步DC (TRDC)对生活在华盛顿特区的高中生(N = 291)自我报告的心理健康指标的作用。方法:在2010年至2018年期间,在7个DC区的10所高中提供TRDC计划。我们在每个学校使用准实验设计来确定TRDC计划的剂量、抑郁指标和参加和不参加该计划的学生的社会联系之间的关系。数据在每个学年的开始和结束时收集,使用流行病学研究中心的儿童抑郁量表和海明威社会联系量表。混合效应回归模型检验了参与剂量与心理健康评分之间的剂量-反应关系。结果:完成至少2年TRDC的高中生与接受不到1年TRDC的学生相比,他们的流行病学研究中心儿童抑郁量表得分降低了6分(β = -5.9; 95% CI, -10.7至-1.0),出现临床抑郁症状的几率降低了69%(优势比= 0.31;95% CI, 0.23至0.42)。同样,与接触不到一年的学生相比,接受两年或两年以上TRDC教育的学生的海明威社会联系总分提高了8分(β = 7.9; 95% CI, 0.65至15.1)。TRDC的好处在女学生中尤为明显。结论:这些发现表明,跑步/辅导项目对高中生的心理健康有实质性的好处,尤其是对少女。
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引用次数: 0
Physical Activity and Older Population: Are the Physical Activity Guidelines Adequate for Low- and Middle-Income Countries? 体力活动与老年人口:体力活动指南是否适合中低收入国家?
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-09-29 Print Date: 2026-01-01 DOI: 10.1123/jpah.2025-0513
Fernanda Castro Monteiro, Ricardo Aurélio Carvalho Sampaio, Bruno Bizzozero-Peroni, Jullyane Caldas Dos Santos, Eduardo Lusa Cadore, Hidenori Arai, Danilo Rodrigues Pereira da Silva
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引用次数: 0
The Causal Relationship Between Physical Activity and Sleep and Eating Disorders: Evidence From a Mendelian Randomization Analysis. 运动与睡眠和饮食失调之间的因果关系:来自孟德尔随机化分析的证据。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-09-25 Print Date: 2026-01-01 DOI: 10.1123/jpah.2025-0152
Decheng Xu, Zhiyuan Sun, Kai Qi, Yahui Yang, Kelong Cai, Zhiyuan Qiao, Aiguo Chen

Background: Sleep and eating disorders are significant global public health concerns. While physical activity (PA) has been suggested to influence these disorders, the nature of this relationship remains unclear. This study aims to investigate whether a causal link exists between PA and sleep and eating disorders.

Methods: This study uses Genome-Wide Association Study data; PA ("ebi-a-GCST90061432") is the exposure, with sleep disorders ("ukb-d-SLEEP") and eating disorders ("finn-b-F5_EATING") as outcomes variable. The study sample consists of a European population, and genetic instrumental variables are carefully selected. Two-sample Mendelian Randomization (MR) analysis is performed using inverse variance weighting, weighted median, and MR-Egger regression.

Results: MR analysis revealed a significant negative association between PA and sleep disorders (inverse variance weighting estimate β = -0.004, SE = 0.002, P = .008). Both the Weighted Median and MR-Egger methods showed negative trends, but not statistically significant (β = -0.003/-0.005, SE = 0.002/0.005, P = .191/0.346). For PA and eating disorders, the inverse variance weighting estimate was β = -0.375 (P = .153), with no significance in the other methods, suggesting a limited effect of PA on eating disorders. Sensitivity (MR-Egger, leave-one-out) and heterogeneity (Q = 29.87, P = .472; I2 = 0.004) analyses confirmed the robustness of these findings (F = 24.49).

Conclusion: This study suggests PA may reduce the risk of sleep disorders, while its impact on eating disorders appears limited. Future research should explore how different types, frequencies, and intensities of PA affect various health conditions to optimize its use in public health.

背景:睡眠和饮食失调是全球重大的公共卫生问题。虽然体力活动(PA)已被认为影响这些疾病,但这种关系的性质尚不清楚。本研究旨在调查PA与睡眠和饮食失调之间是否存在因果关系。方法:本研究使用全基因组关联研究数据;PA(“ebi-a-GCST90061432”)是暴露,睡眠障碍(“ukb-d-SLEEP”)和饮食障碍(“fin -b- f5_eating”)是结果变量。研究样本由欧洲人口组成,遗传工具变量是精心选择的。双样本孟德尔随机化(MR)分析采用方差逆加权、加权中位数和MR- egger回归。结果:MR分析显示PA与睡眠障碍之间存在显著负相关(方差加权逆估计β = -0.004, SE = 0.002, P = 0.008)。加权中位数法和MR-Egger法均呈负相关,但无统计学意义(β = -0.003/-0.005, SE = 0.002/0.005, P = 0.191 /0.346)。对于PA和饮食失调,方差加权逆估计为β = -0.375 (P = 0.153),在其他方法中无显著性,提示PA对饮食失调的影响有限。敏感性(MR-Egger,留一)和异质性(Q = 29.87, P = .472; I2 = 0.004)分析证实了这些发现的稳健性(F = 24.49)。结论:这项研究表明,PA可能会降低睡眠障碍的风险,而其对饮食障碍的影响似乎有限。未来的研究应探讨不同类型、频率和强度的PA对各种健康状况的影响,以优化其在公共卫生中的应用。
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引用次数: 0
Unlocking the Effects of Seasonal Changes on Mobility, Activity, and Lifestyle in Rural Older Adults Living Alone: Insights From a Clustering Analysis. 解开季节变化对农村独居老年人流动性、活动和生活方式的影响:来自聚类分析的见解。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-09-24 Print Date: 2025-12-01 DOI: 10.1123/jpah.2025-0066
Catarina F Martins, Lara Carneiro, Carlos Figueiredo, Maria P Mota

Background: Seasonality profoundly impacts older adults in rural communities, influencing daily routines, physical activity (PA), and functionality. Effective interventions require a nuanced understanding of these variations particularly for those living alone.

Methods: This longitudinal study examined 58 older adults (mean age 80.22 y) living alone in a rural community across summer and winter. Variables assessed included sociodemographics, lifestyle factors, weekly social contacts, a composite index of agricultural activity, independence in daily activities, functional status, and weather conditions. PA was measured using an ActiGraph GT9X accelerometer. Paired t tests and K-means cluster analysis were applied, followed by discriminant analysis and cluster evolution monitoring.

Results: Significant seasonal differences were observed in lifestyle, weekly contacts, agricultural activity, and PA. Engagement in agricultural activities correlated with higher PA levels during summer and lower sedentary behavior in both seasons. Cluster analysis identified 3 distinct groups each season, with unique levels of PA, functionality, and behaviors. The discriminant analysis highlighted seasonal patterns, while the bipartite graph analysis showed subject reaggregation in winter, illustrating cluster composition shifts.

Conclusion: This study demonstrates that older adults living alone in rural areas are vulnerable to seasonal variations, with higher PA, more frequent social contacts, and greater agricultural engagement in summer than in winter. Cluster analysis revealed 3 groups of older adults each season, underscoring the necessity for customized interventions that consider behavioral patterns, specific needs, and seasonal changes. The significance of suitable interventions to improve social interactions and prevent functional decline is emphasized.

背景:季节性深刻影响农村社区老年人,影响日常生活、身体活动(PA)和功能。有效的干预需要对这些差异有细致入微的了解,尤其是对独居者。方法:这项纵向研究调查了夏季和冬季在农村社区独居的58名老年人(平均年龄80.22岁)。评估的变量包括社会人口统计学、生活方式因素、每周社会接触、农业活动综合指数、日常活动的独立性、功能状态和天气条件。使用ActiGraph GT9X加速度计测量PA。采用配对t检验和K-means聚类分析,然后进行判别分析和聚类演化监测。结果:在生活方式、每周接触、农业活动和PA方面观察到显著的季节性差异。从事农业活动与夏季较高的PA水平和两个季节较低的久坐行为相关。聚类分析确定了每个季节3个不同的群体,具有独特的PA水平,功能和行为。判别分析突出了季节特征,二部图分析显示主体在冬季重新聚集,说明了聚类构成的变化。结论:该研究表明,农村独居老年人易受季节变化的影响,其PA较高,社会接触更频繁,夏季农业参与程度高于冬季。聚类分析显示,每个季节有三组老年人,强调了考虑行为模式、特定需求和季节变化的定制干预的必要性。强调了适当的干预措施对改善社会互动和预防功能衰退的重要性。
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引用次数: 0
Using Data-Driven Insights to Explore the Variability in Pupils' Physical Activity Between English Primary Schools. 使用数据驱动的见解来探索英国小学学生体育活动的差异。
IF 2.6 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-09-24 Print Date: 2025-10-01 DOI: 10.1123/jpah.2024-0868
Georgina K Wort, Ruth Salway, Oliver Peacock, Simon Sebire, Dylan Thompson

Background: Characterizing interindividual differences in physical activity within schools and understanding potential drivers of these differences may support the development of improved strategies to increase in-school physical activity.

Methods: Anonymized physical activity data from a school-specific wrist-worn device were obtained from 17,043 pupils and 2555 staff from 165 primary schools in England. Additional school information included UK government school data, area-level deprivation, and estimated playground area. Descriptive statistics were calculated, and data visualizations were used to explore within- and between-school differences. Multilevel models were used to explore the associations between children's in-school physical activity and school variables, with pupils nested within schools, adjusted for individual characteristics.

Results: There was large variation in physical activity between schools. Some schools accumulated twice the amount of physical activity within the school day compared with other schools, with physical activity ranging from 4253 to 8356 steps per school day or 16 to 39 minutes of moderate to vigorous physical activity per school day. School-level data, such as playground space and government school ratings, did not explain between-school variance. Although boys were generally more active than girls in most schools, some schools had more equitable physical activity, and in a small number of schools (∼5%), girls were more active than boys.

Conclusions: There is considerable heterogeneity in physical activity levels between English primary schools. Technology-enabled surveillance from wearable devices can be used to identify schools needing greater support and facilitate learning from those with higher and more equitable physical activity among pupils.

背景:描述学校内体育活动的个体间差异并了解这些差异的潜在驱动因素可能有助于制定改进的策略来增加学校内的体育活动。方法:从英国165所小学的17043名学生和2555名教职员工中获得了一种学校专用腕带设备的匿名体育活动数据。其他学校信息包括英国政府学校数据、地区水平剥夺和估计操场面积。计算描述性统计数据,并使用数据可视化来探索学校内部和学校之间的差异。多层模型用于探索儿童在校体育活动与学校变量之间的关联,学生嵌套在学校内,根据个人特征进行调整。结果:不同学校学生在体育活动方面存在较大差异。有些学校在校期间的体力活动是其他学校的两倍,每天的体力活动从4253步到8356步不等,或者每天进行16到39分钟的中度到剧烈的体力活动。学校层面的数据,如操场空间和政府学校评级,并不能解释学校之间的差异。虽然在大多数学校中,男孩普遍比女孩更活跃,但有些学校的体育活动更为公平,而且在少数学校(约5%),女孩比男孩更活跃。结论:英语小学体育活动水平存在较大的异质性。可穿戴设备的技术监控可用于确定需要更多支持的学校,并促进学生向那些体育活动更高、更公平的学校学习。
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引用次数: 0
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