Pub Date : 2024-07-01DOI: 10.4103/jpbs.jpbs_395_24
Piyush Javiya, T. Anjan, S. Duseja, Jeevan Matada Basavarajaiah, Jignesh Tate, Rahul Puthenkandathil, F. Baig
ABSTRACT Dental implants are now the typical tooth replacement method. Because it speeds up therapy, quick functional loading—attaching prosthetic restorations to implants following surgery—has become popular. Flapless implant implantation reduces surgical stress and expedites recovery. A prospective comparative study of 100 flap and flapless dental implant patients was done. Patient-reported outcomes, implant survival, peri-implant parameters, and surgical complications were assessed. Statistical analysis compared the two groups’ results. Both flap and flapless methods exhibited good implant survival and similar peri-implant characteristics. Patients reported equal postoperative comfort and satisfaction in both groups. Surgical complications were similar for flap and flapless surgeries. In immediate functional loading, flap and flapless implant insertion are equally effective and safe. Both methods yield dependable implant survival, peri-implant health, patient comfort, and surgical safety. Dental professionals should evaluate patient variables and anatomical aspects while choosing an implant implantation surgery. Implant dentistry needs further study on long-term results and treatment regimens.
{"title":"Flap Versus Flapless Implant Placement in Immediate Functional Loading: A Comparative Study","authors":"Piyush Javiya, T. Anjan, S. Duseja, Jeevan Matada Basavarajaiah, Jignesh Tate, Rahul Puthenkandathil, F. Baig","doi":"10.4103/jpbs.jpbs_395_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_395_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 Dental implants are now the typical tooth replacement method. Because it speeds up therapy, quick functional loading—attaching prosthetic restorations to implants following surgery—has become popular. Flapless implant implantation reduces surgical stress and expedites recovery.\u0000 \u0000 \u0000 \u0000 A prospective comparative study of 100 flap and flapless dental implant patients was done. Patient-reported outcomes, implant survival, peri-implant parameters, and surgical complications were assessed. Statistical analysis compared the two groups’ results.\u0000 \u0000 \u0000 \u0000 Both flap and flapless methods exhibited good implant survival and similar peri-implant characteristics. Patients reported equal postoperative comfort and satisfaction in both groups. Surgical complications were similar for flap and flapless surgeries.\u0000 \u0000 \u0000 \u0000 In immediate functional loading, flap and flapless implant insertion are equally effective and safe. Both methods yield dependable implant survival, peri-implant health, patient comfort, and surgical safety. Dental professionals should evaluate patient variables and anatomical aspects while choosing an implant implantation surgery. Implant dentistry needs further study on long-term results and treatment regimens.\u0000","PeriodicalId":16824,"journal":{"name":"Journal of Pharmacy and Bioallied Sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141711549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.4103/jpbs.jpbs_401_24
F. Baig, S. K. Beniwal, P. V. Samir, Gokul Venkateshwar, Mamta Singh, Siva Kumar Pendyala
ABSTRACT The purpose of this study was to compare the efficacy of various suturing methods used in deep third molar extraction procedures. A total of four suturing method groups—simple interrupted, horizontal mattress, vertical mattress, and figure-of-eight—were randomly allocated to 100 patients having deep third molar surgery. Assessments were conducted on wound healing, operation time, intraoperative problems, postoperative pain scores, swelling measures, and patient satisfaction questionnaires. Appropriate tests were used for statistical analysis, with P < 0.05 being regarded as significant. Compared to other procedures, the figure-of-eight technique showed better results in terms of postoperative pain scores, swelling measures, wound healing percentages, and patient satisfaction (P < 0.05). There was no discernible difference in the operating time or intraoperative problems between the groups. In conclusion, there seems to be a benefit to using the figure-of-eight suturing approach for deep third molar surgery in terms of improved postoperative results and patient satisfaction. It is recommended that clinicians give this strategy some thought to improve patient care and surgical results.
{"title":"Evlaution of Different Suturing Techniques in Deep Third Molar Surgery: An Original Research","authors":"F. Baig, S. K. Beniwal, P. V. Samir, Gokul Venkateshwar, Mamta Singh, Siva Kumar Pendyala","doi":"10.4103/jpbs.jpbs_401_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_401_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 The purpose of this study was to compare the efficacy of various suturing methods used in deep third molar extraction procedures.\u0000 \u0000 \u0000 \u0000 A total of four suturing method groups—simple interrupted, horizontal mattress, vertical mattress, and figure-of-eight—were randomly allocated to 100 patients having deep third molar surgery. Assessments were conducted on wound healing, operation time, intraoperative problems, postoperative pain scores, swelling measures, and patient satisfaction questionnaires. Appropriate tests were used for statistical analysis, with P < 0.05 being regarded as significant.\u0000 \u0000 \u0000 \u0000 Compared to other procedures, the figure-of-eight technique showed better results in terms of postoperative pain scores, swelling measures, wound healing percentages, and patient satisfaction (P < 0.05). There was no discernible difference in the operating time or intraoperative problems between the groups.\u0000 \u0000 \u0000 \u0000 In conclusion, there seems to be a benefit to using the figure-of-eight suturing approach for deep third molar surgery in terms of improved postoperative results and patient satisfaction. It is recommended that clinicians give this strategy some thought to improve patient care and surgical results.\u0000","PeriodicalId":16824,"journal":{"name":"Journal of Pharmacy and Bioallied Sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141692382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.4103/jpbs.jpbs_272_24
Md Miftah ur Rahman, Rupasree Gundala, Kavita Gupta, Diptesh S. Rami, Nilesh Bhanawat, H. Dewan, Vilas Patel, Sirisha Kommuri
ABSTRACT Implant-supported prostheses have become a cornerstone of restorative dentistry, offering patients an effective solution for missing teeth. However, the choice of material for these prostheses can significantly impact their maintenance requirements and long-term success. Patient records of individuals who received implant-supported prostheses over a 2-year period were reviewed. Data on maintenance interventions, including adjustments, repairs, and replacements were collected and analyzed for metal alloys, ceramics, and composites. Metal alloys exhibited slightly higher average numbers of adjustments compared to ceramics and composites. Ceramics required a higher mean number of repairs and replacements compared to other materials. Statistical analysis revealed significant differences in adjustment frequency between metal alloys and ceramics (P = 0.047), but no significant differences were observed for repairs or replacements. The outcomes imply that material choice plays a significant role in the maintenance requirements of implant dental prostheses. While metal alloys may require more frequent adjustments, ceramics and composites may necessitate more repairs and replacements over time. Clinicians should consider these factors when selecting materials for implant prostheses and develop tailored maintenance protocols to optimize treatment outcomes.
{"title":"Evaluation of Different Materials used in Prosthetic of Dental Implants: A Comparitive Study","authors":"Md Miftah ur Rahman, Rupasree Gundala, Kavita Gupta, Diptesh S. Rami, Nilesh Bhanawat, H. Dewan, Vilas Patel, Sirisha Kommuri","doi":"10.4103/jpbs.jpbs_272_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_272_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 Implant-supported prostheses have become a cornerstone of restorative dentistry, offering patients an effective solution for missing teeth. However, the choice of material for these prostheses can significantly impact their maintenance requirements and long-term success.\u0000 \u0000 \u0000 \u0000 Patient records of individuals who received implant-supported prostheses over a 2-year period were reviewed. Data on maintenance interventions, including adjustments, repairs, and replacements were collected and analyzed for metal alloys, ceramics, and composites.\u0000 \u0000 \u0000 \u0000 Metal alloys exhibited slightly higher average numbers of adjustments compared to ceramics and composites. Ceramics required a higher mean number of repairs and replacements compared to other materials. Statistical analysis revealed significant differences in adjustment frequency between metal alloys and ceramics (P = 0.047), but no significant differences were observed for repairs or replacements.\u0000 \u0000 \u0000 \u0000 The outcomes imply that material choice plays a significant role in the maintenance requirements of implant dental prostheses. While metal alloys may require more frequent adjustments, ceramics and composites may necessitate more repairs and replacements over time. Clinicians should consider these factors when selecting materials for implant prostheses and develop tailored maintenance protocols to optimize treatment outcomes.\u0000","PeriodicalId":16824,"journal":{"name":"Journal of Pharmacy and Bioallied Sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141699187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Access cavity preparation, chemo-mechanical preparation, and obturation make up the majority of the endodontic triad. Every action should be carefully observed by the clinician. In the last two decades, endodontics has seen advancements in both technology and materials. Given the technical advancements in applied sciences, magnification, and imaging techniques, minimally invasive therapies are currently used in the medical and dentistry industries. This review article will describe minimally invasive Access cavity designs and their advantages and disadvantages in Endodontic treatment.
{"title":"Minimally Invasive Access Cavity Designs: A Review","authors":"Sushmita Rane, V. Pandit, Ashwini Gaikwad, Shivani Chavan, Rajlaxmi Patil, Mrunal Shinde","doi":"10.4103/jpbs.jpbs_450_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_450_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 Access cavity preparation, chemo-mechanical preparation, and obturation make up the majority of the endodontic triad. Every action should be carefully observed by the clinician. In the last two decades, endodontics has seen advancements in both technology and materials. Given the technical advancements in applied sciences, magnification, and imaging techniques, minimally invasive therapies are currently used in the medical and dentistry industries. This review article will describe minimally invasive Access cavity designs and their advantages and disadvantages in Endodontic treatment.","PeriodicalId":16824,"journal":{"name":"Journal of Pharmacy and Bioallied Sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141705567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Josh, K. Thanveer, Supurna Pandit, P. Divekar, Rakesh Kumar Pandey, Minakshi
ABSTRACT Oral health related quality of life (OHRQoL), locus of control, dental health as assessed by oneself and oral health situation have all been the subject of several research, but none of them have yet been investigated in combination. This cross-sectional study was carried out on 525 nursing students to investigate these ideas. The Oral Health Impact Profile-14 (OHIP-14) scale was employed to evaluate the standard of living associated with oral health. Both chance participants and group internals reported having good OHRQoL. Nursing students in the internals group accurately assessed the deteriorated aspect of their self-reported oral health. However, it was found that participants from the chance locus and powerful others were unable to accurately rate the decayed component (P < 0.05). Internal nursing students had the highest OHRQoL, followed by random and influential students. Individuals from locus internals and random gave accurate ratings of their dental deterioration.
{"title":"Oral Health-Related Quality of Life, Locus of Control, Self-Reported Oral Health and Oral Health Status among Nursing Students in Moradabad","authors":"J. Josh, K. Thanveer, Supurna Pandit, P. Divekar, Rakesh Kumar Pandey, Minakshi","doi":"10.4103/jpbs.jpbs_97_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_97_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 Oral health related quality of life (OHRQoL), locus of control, dental health as assessed by oneself and oral health situation have all been the subject of several research, but none of them have yet been investigated in combination.\u0000 \u0000 \u0000 \u0000 This cross-sectional study was carried out on 525 nursing students to investigate these ideas. The Oral Health Impact Profile-14 (OHIP-14) scale was employed to evaluate the standard of living associated with oral health.\u0000 \u0000 \u0000 \u0000 Both chance participants and group internals reported having good OHRQoL. Nursing students in the internals group accurately assessed the deteriorated aspect of their self-reported oral health. However, it was found that participants from the chance locus and powerful others were unable to accurately rate the decayed component (P < 0.05).\u0000 \u0000 \u0000 \u0000 Internal nursing students had the highest OHRQoL, followed by random and influential students. Individuals from locus internals and random gave accurate ratings of their dental deterioration.\u0000","PeriodicalId":16824,"journal":{"name":"Journal of Pharmacy and Bioallied Sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141693633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.4103/jpbs.jpbs_408_24
Abhishek M P, Sileveru Chandra Mouli, M. Shariff, Maryada Sravani, Kirti Malik, Himani Dadwal, Rahul Anand
ABSTRACT Current research compared traditional FESS, balloon sinuplasty, and powered instruments for CRS efficiency. A prospective comparison analysis of 150 CRS patients who received FESS. The surgical method divided the patients into three groups: Group A (conventional FESS, n = 50), Group B (balloon sinuplasty, n = 50), and Group C (powered instrumentation, n = 50). Primary outcome measures included symptom alleviation, measured preoperatively and six months postoperatively using the “22-item Sino-Nasal Outcome Test (SNOT-22)”. Preoperative and six-month postoperative “Short Form 36 (SF-36)” Health Surveys assessed postoperative complications and the quality of life. Balloon sinuplasty relieved symptoms better than FESS and powered instrumentation. Mean SNOT-22 scores reduced by 62.1% in the balloon sinuplasty group, much higher than the standard FESS and powered instrumentation groups (49.1% and 45.8%, respectively) (P < 0.001). Balloon sinuplasty had fewer postoperative problems than FESS and powered instrumentation, including bleeding, infection, and synechia. Balloon sinuplasty treats CRS better than FESS and powered instrumentation and has fewer postoperative sequelae. These data imply that balloon sinuplasty may be a preferred FESS surgical strategy for CRS, but patient-specific characteristics and disease severity must be considered. Current findings need to be confirmed by larger studies with longer follow-up periods to determine the best FESS surgical strategy for CRS.
{"title":"Efficiency of Different Approaches in Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: A Comparative Study","authors":"Abhishek M P, Sileveru Chandra Mouli, M. Shariff, Maryada Sravani, Kirti Malik, Himani Dadwal, Rahul Anand","doi":"10.4103/jpbs.jpbs_408_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_408_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 Current research compared traditional FESS, balloon sinuplasty, and powered instruments for CRS efficiency.\u0000 \u0000 \u0000 \u0000 A prospective comparison analysis of 150 CRS patients who received FESS. The surgical method divided the patients into three groups: Group A (conventional FESS, n = 50), Group B (balloon sinuplasty, n = 50), and Group C (powered instrumentation, n = 50). Primary outcome measures included symptom alleviation, measured preoperatively and six months postoperatively using the “22-item Sino-Nasal Outcome Test (SNOT-22)”. Preoperative and six-month postoperative “Short Form 36 (SF-36)” Health Surveys assessed postoperative complications and the quality of life.\u0000 \u0000 \u0000 \u0000 Balloon sinuplasty relieved symptoms better than FESS and powered instrumentation. Mean SNOT-22 scores reduced by 62.1% in the balloon sinuplasty group, much higher than the standard FESS and powered instrumentation groups (49.1% and 45.8%, respectively) (P < 0.001). Balloon sinuplasty had fewer postoperative problems than FESS and powered instrumentation, including bleeding, infection, and synechia.\u0000 \u0000 \u0000 \u0000 Balloon sinuplasty treats CRS better than FESS and powered instrumentation and has fewer postoperative sequelae. These data imply that balloon sinuplasty may be a preferred FESS surgical strategy for CRS, but patient-specific characteristics and disease severity must be considered. Current findings need to be confirmed by larger studies with longer follow-up periods to determine the best FESS surgical strategy for CRS.\u0000","PeriodicalId":16824,"journal":{"name":"Journal of Pharmacy and Bioallied Sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141691091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.4103/jpbs.jpbs_153_24
A. Lingam, Sara A. Al Hussein, Maha K. Alghunaim, R. Abdelrahim, Pradeep Koppolu, Vasanthi Done, Shaimaa F K Habib, Hagar Samran, A. M. Alghawazi
ABSTRACT Malocclusion and lifestyle diseases like obesity can lead to poor oral hygiene and food stagnation, resulting in increased caries incidence. To evaluate the interrelationship of age, body mass index (BMI), occlusion, and dental decay in children aged between 5 and 14. Our study included 423 school students aged 5-14 visiting dental clinics. Correlation between BMI and DMFT index using Spearman’s correlation coefficient and the association of BMI with gender, age group, and occlusion using the Chi-square test were assessed. The study comprised a larger sample of students aged above 10 years (n = 217) and between 6 and 10 years (n = 183), with Angle’s Class I and II malocclusion being predominant. A weak positive correlation was found between BMI and the missing component of the DMFT index, while significant statistical associations were observed between underweight students below 5 years (8.5%) and obesity in those between 6 and 8 years (53.3%) (P < 0.05). Dental practitioners must pay attention to the BMI of children and consider diet as a major intervention for dental caries prophylaxis.
{"title":"Relationship Between Body Mass Index, Occlusion, and Dental Caries among School Children in Riyadh","authors":"A. Lingam, Sara A. Al Hussein, Maha K. Alghunaim, R. Abdelrahim, Pradeep Koppolu, Vasanthi Done, Shaimaa F K Habib, Hagar Samran, A. M. Alghawazi","doi":"10.4103/jpbs.jpbs_153_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_153_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 Malocclusion and lifestyle diseases like obesity can lead to poor oral hygiene and food stagnation, resulting in increased caries incidence.\u0000 \u0000 \u0000 \u0000 To evaluate the interrelationship of age, body mass index (BMI), occlusion, and dental decay in children aged between 5 and 14.\u0000 \u0000 \u0000 \u0000 Our study included 423 school students aged 5-14 visiting dental clinics. Correlation between BMI and DMFT index using Spearman’s correlation coefficient and the association of BMI with gender, age group, and occlusion using the Chi-square test were assessed.\u0000 \u0000 \u0000 \u0000 The study comprised a larger sample of students aged above 10 years (n = 217) and between 6 and 10 years (n = 183), with Angle’s Class I and II malocclusion being predominant. A weak positive correlation was found between BMI and the missing component of the DMFT index, while significant statistical associations were observed between underweight students below 5 years (8.5%) and obesity in those between 6 and 8 years (53.3%) (P < 0.05).\u0000 \u0000 \u0000 \u0000 Dental practitioners must pay attention to the BMI of children and consider diet as a major intervention for dental caries prophylaxis.\u0000","PeriodicalId":16824,"journal":{"name":"Journal of Pharmacy and Bioallied Sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141690275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Ocular surface squamous neoplasia (OSSN) encompasses a range of dysplastic changes from mild dysplasia to invasive carcinoma. This research aims to elucidate the cytomorphological spectrum of OSSN in the elderly age group and correlate these findings with clinical and pathological features. A retrospective analysis was conducted on elderly patients (>60 years) diagnosed with OSSN over a 5 year period. Cytological and histopathological findings were analyzed and correlated with clinical data. The cytomorphological spectrum of OSSN in the elderly age group exhibited a broad range of cellular changes, from mild dysplasia to invasive squamous cell carcinoma. The predominant cytological features included increased nuclear–cytoplasmic ratio, pleomorphism, and abnormal mitotic figures. Clinically, OSSN presented most commonly as a unilateral conjunctival mass with a history of chronic irritation. Histopathologically, there was a significant correlation between the degree of dysplasia and the depth of invasion (P < 0.05). This research highlights the diverse cytomorphological spectrum of OSSN in the elderly age groups and emphasizes the importance of comprehensive clinicopathological correlation for accurate diagnosis and management. The predominant cytological features observed, including increased nuclear–cytoplasmic ratio, pleomorphism, and abnormal mitotic figures, reflect the underlying dysplastic alterations and provide valuable insights into the diagnosis and the classification of OSSN. Further studies are warranted to explore the potential role of impression cytology in the diagnosis and management of OSSN and to evaluate the efficacy of different treatment modalities in the elderly age group.
{"title":"Cytomorphological Spectrum of Ocular Surface Squamous Neoplasia in Elderly Age Group and Its Clinicopathological Correlation","authors":"Anju Singh, Ankita Sharma, Shivi Srivastava, Akarshi Jaiswal, Kekhrieneinuo Mere, Heena Dixit, Ashish Mahobia","doi":"10.4103/jpbs.jpbs_410_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_410_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 Ocular surface squamous neoplasia (OSSN) encompasses a range of dysplastic changes from mild dysplasia to invasive carcinoma. This research aims to elucidate the cytomorphological spectrum of OSSN in the elderly age group and correlate these findings with clinical and pathological features.\u0000 \u0000 \u0000 \u0000 A retrospective analysis was conducted on elderly patients (>60 years) diagnosed with OSSN over a 5 year period. Cytological and histopathological findings were analyzed and correlated with clinical data.\u0000 \u0000 \u0000 \u0000 The cytomorphological spectrum of OSSN in the elderly age group exhibited a broad range of cellular changes, from mild dysplasia to invasive squamous cell carcinoma. The predominant cytological features included increased nuclear–cytoplasmic ratio, pleomorphism, and abnormal mitotic figures. Clinically, OSSN presented most commonly as a unilateral conjunctival mass with a history of chronic irritation. Histopathologically, there was a significant correlation between the degree of dysplasia and the depth of invasion (P < 0.05).\u0000 \u0000 \u0000 \u0000 This research highlights the diverse cytomorphological spectrum of OSSN in the elderly age groups and emphasizes the importance of comprehensive clinicopathological correlation for accurate diagnosis and management. The predominant cytological features observed, including increased nuclear–cytoplasmic ratio, pleomorphism, and abnormal mitotic figures, reflect the underlying dysplastic alterations and provide valuable insights into the diagnosis and the classification of OSSN. Further studies are warranted to explore the potential role of impression cytology in the diagnosis and management of OSSN and to evaluate the efficacy of different treatment modalities in the elderly age group.\u0000","PeriodicalId":16824,"journal":{"name":"Journal of Pharmacy and Bioallied Sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141693614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.4103/jpbs.jpbs_424_24
Digvijaysinh Parmar, Nuha S. Alghamdi, Swetha Bellam, Jasmine Kaur, Abikshyeet Panda, Rasangnya Yedla, Nallamilli Lalitha Sri Roja
ABSTRACT The management of dental caries presents challenges for oral health professionals, with options including conservative and surgical interventions. However, debate persists regarding the long-term efficacy of these strategies. This retrospective cohort research involved 500 subjects diagnosed with dental caries at the University Dental Clinic between January 1, 2018, and December 31, 2020. Data on demographics, dental history, treatments, and follow-up were collected from patient records. Subjects were categorized into conservative and surgical groups based on treatment received. Outcome measures included tooth survival, caries recurrence, and patient satisfaction. The research included 300 subjects, with 60% under conservative management and 40% under surgical management. Demographics were comparable between groups, and both groups showed similar outcomes in tooth survival, caries recurrence, and patient satisfaction. Statistical analysis revealed no significant differences in these outcomes between groups. Conservative and surgical management approaches demonstrate comparable long-term outcomes in treating dental caries, emphasizing the importance of personalized treatment decisions. Further research with larger samples and prospective designs is needed to validate these findings and guide evidence-based practice in dental caries management.
{"title":"Long-Term Outcomes of Conservative versus Surgical Management of Dental Caries","authors":"Digvijaysinh Parmar, Nuha S. Alghamdi, Swetha Bellam, Jasmine Kaur, Abikshyeet Panda, Rasangnya Yedla, Nallamilli Lalitha Sri Roja","doi":"10.4103/jpbs.jpbs_424_24","DOIUrl":"https://doi.org/10.4103/jpbs.jpbs_424_24","url":null,"abstract":"ABSTRACT\u0000 \u0000 \u0000 \u0000 The management of dental caries presents challenges for oral health professionals, with options including conservative and surgical interventions. However, debate persists regarding the long-term efficacy of these strategies.\u0000 \u0000 \u0000 \u0000 This retrospective cohort research involved 500 subjects diagnosed with dental caries at the University Dental Clinic between January 1, 2018, and December 31, 2020. Data on demographics, dental history, treatments, and follow-up were collected from patient records. Subjects were categorized into conservative and surgical groups based on treatment received. Outcome measures included tooth survival, caries recurrence, and patient satisfaction.\u0000 \u0000 \u0000 \u0000 The research included 300 subjects, with 60% under conservative management and 40% under surgical management. Demographics were comparable between groups, and both groups showed similar outcomes in tooth survival, caries recurrence, and patient satisfaction. Statistical analysis revealed no significant differences in these outcomes between groups.\u0000 \u0000 \u0000 \u0000 Conservative and surgical management approaches demonstrate comparable long-term outcomes in treating dental caries, emphasizing the importance of personalized treatment decisions. Further research with larger samples and prospective designs is needed to validate these findings and guide evidence-based practice in dental caries management.\u0000","PeriodicalId":16824,"journal":{"name":"Journal of Pharmacy and Bioallied Sciences","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141706551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.4103/jpbs.jpbs_409_24
Asma Ahmed, Rajunaik Ajmeera, M. Bagrecha, Ganaraj Shetty, D. Mallika, Priyanka Sharma, Raj Kumar Tiwari
ABSTRACT To assess how well steroidal nasal sprays and oral steroids work for treating CRS. Two hundred patients with CRS were included in a randomized controlled experiment. The patients were split into two groups: Group B received steroidal nasal sprays (fluticasone propionate 110 mcg/day in each nostril for 12 weeks) and Group A received oral steroids (prednisolone 30 mg/day for 14 days, followed by tapering over 7 days). The “Sino-Nasal Outcome Test (SNOT-22)” was used to quantify improvement in symptoms, the “Rhinosinusitis Disability Index (RSDI)” was used to measure quality of life, and the recurrence rate was measured at the 6-month follow-up. At 12 weeks, SNOT-22 and RSDI scores significantly improved with both oral steroids and steroidal nasal sprays (P < 0.05). At the 6-month follow-up, however, oral steroids had a greater recurrence rate (25% vs. 12%, P = 0.02) when compared to steroidal nasal sprays. The two groups’ adverse effects were similar and of low severity. In conclusion, nasal sprays containing steroids seem to be a safer and more successful option than oral steroids for treating CRS, making them worthy of being used as the first line of treatment.
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