M. Spasova, I. Ivanov, J. Grudeva-Popova, A. Stoyanova, H. Dimitrov, I. N. Moumdjiev
The authors report a 4-year-old male with Hodgkin's disease with atypical clinical presentation, laboratory data and imaging studies as well as an increased radiosensitivity. These were the first symptoms which raised the suspicion of ataxia-telangiectasia. The lymphoma presented as a solid tumor mass in the right upper posterior mediastinum without peripheral lymphadenopathy. The alpha-fetoprotein was significantly increased and the diagnosis of a germ-cell tumor or neuroblastoma was suspected. After partial resection of the tumor the histology indicated Hodgkin's disease-mixed cellularity. The boy received chemotherapy according to DAL HD-95 protocol without any unusual toxicity. Low-dose radiation therapy of the upper and middle mediastinum was followed by early radiation-induced esophagitis and appearance of a large pericardial effusion one year later. Ataxia and bulbar and skin telangiectasias at the radiation site appeared in the next years. He suffered recurrent pulmonary infections and succumbed to severe pneumonia with respiratory failure and pulmonary hypertension five years after the diagnosis of malignant lymphoma without evidence of recurrence of Hodgkin's disease.
{"title":"Hodgkin's Disease with Atypical Clinical Presentation, Associated with Ataxia-Telangiectasia","authors":"M. Spasova, I. Ivanov, J. Grudeva-Popova, A. Stoyanova, H. Dimitrov, I. N. Moumdjiev","doi":"10.3814/2009/974576","DOIUrl":"https://doi.org/10.3814/2009/974576","url":null,"abstract":"The authors report a 4-year-old male with Hodgkin's disease with atypical clinical presentation, laboratory data and imaging studies as well as an increased radiosensitivity. These were the first symptoms which raised the suspicion of ataxia-telangiectasia. The lymphoma presented as a solid tumor mass in the right upper posterior mediastinum without peripheral lymphadenopathy. The alpha-fetoprotein was significantly increased and the diagnosis of a germ-cell tumor or neuroblastoma was suspected. After partial resection of the tumor the histology indicated Hodgkin's disease-mixed cellularity. The boy received chemotherapy according to DAL HD-95 protocol without any unusual toxicity. Low-dose radiation therapy of the upper and middle mediastinum was followed by early radiation-induced esophagitis and appearance of a large pericardial effusion one year later. Ataxia and bulbar and skin telangiectasias at the radiation site appeared in the next years. He suffered recurrent pulmonary infections and succumbed to severe pneumonia with respiratory failure and pulmonary hypertension five years after the diagnosis of malignant lymphoma without evidence of recurrence of Hodgkin's disease.","PeriodicalId":169134,"journal":{"name":"Scholarly Research Exchange","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125233021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this study was to compare the histologic findings from the condyles of rats with the general system findings. 30 Sprague-Dawley adult rats were used. The rats were sacrified and their condyles and femurs were examined histologically. The rats’ weight were observed weekly, their femoral height and weight, femoral mineral elements, and their daily food and water consumes were recorded. The results were analysed statistically by using SPSS (10.0). During the histologic examination of femur, the osteogenesis and calcification of the femur layers of the male/female rats in the experimental group were found to be lower than those of the ones in the control group. In addition to that, during the histological examination of condyle the level of thickness of condyle layers, the number of cellular elements, the osteogenesis and calcification seemed to be decreased for the male/female rats in the experimental group than for those in the control group. The decrease was found to be more significant for the female rats than the male rats in experimental group and it is thought that this is related to the gonad hormones. These findings emphasize that a reduction of sex hormone levels, induced by adrenalectomy, significantly influences condylar histogenesis.
{"title":"Histologic Effects of Bilateral Adrenalectomy under the Light Microscopy on Rat Mandibular Condyle","authors":"S. Z. Ulku, A. Zengingul, A. Ketani","doi":"10.3814/2009/478468","DOIUrl":"https://doi.org/10.3814/2009/478468","url":null,"abstract":"The aim of this study was to compare the histologic findings from \u0000the condyles of rats with the general system findings. 30 \u0000Sprague-Dawley adult rats were used. The rats were sacrified and \u0000their condyles and femurs were examined histologically. The rats’ \u0000weight were observed weekly, their femoral height and weight, \u0000femoral mineral elements, and their daily food and water consumes \u0000were recorded. The results were analysed statistically by using \u0000SPSS (10.0). During the histologic examination of femur, the osteogenesis and calcification of the femur layers of the male/female rats in the experimental group were found to be lower than those of the ones in the control group. In addition to that, during the histological examination of condyle the level of thickness of condyle layers, the number of cellular elements, the osteogenesis and calcification seemed to be decreased for the male/female rats in the experimental group than for those in the control group. The decrease was found to be more significant for the female rats than the male rats in experimental group and it is thought that this is related to the gonad hormones. These findings emphasize that a reduction of sex hormone levels, induced by adrenalectomy, significantly influences condylar histogenesis.","PeriodicalId":169134,"journal":{"name":"Scholarly Research Exchange","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114626797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Moschettoni, D. Lisciani, G. Cacciotti, M. Fraioli
We report a case and discuss clinical features and radiological differential diagnosis of dorsal idiopathic extramedullary arachnoid cyst associated to a caudal syringomyelic cavitation. The aim of this article is to review the current literature on a rare topic as idiopathic intradural extramedullary arachnoid cyst with associated syringomyelia. We emphasize the fact that correct diagnosis and adequate treatment, which we believe is microsurgical fenestration of the cyst into the subarachnoid space, may lead to disappearance of syringomyelia and complete resolution of preoperative spinal cord compression symptoms.
{"title":"Idiopathic Intradural Extramedullary Arachnoid Cyst and Associated Syringomyelia","authors":"L. Moschettoni, D. Lisciani, G. Cacciotti, M. Fraioli","doi":"10.3814/2009/452627","DOIUrl":"https://doi.org/10.3814/2009/452627","url":null,"abstract":"We report a case and discuss clinical features and radiological differential diagnosis of dorsal idiopathic extramedullary arachnoid cyst associated to a caudal syringomyelic cavitation. The aim of this article is to review the current literature on a rare topic as idiopathic intradural extramedullary arachnoid cyst with associated syringomyelia. We emphasize the fact that correct diagnosis and adequate treatment, which we believe is microsurgical fenestration of the cyst into the subarachnoid space, may lead to disappearance of syringomyelia and complete resolution of preoperative spinal cord compression symptoms.","PeriodicalId":169134,"journal":{"name":"Scholarly Research Exchange","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130879600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evaluation of joint toxic action of metal ion mixtures is one of the priority research areas due to the simultaneous occurrence of metals in the environment and the health risk they posed to humans and the environment as a mixture. Individual and composite mixture acute toxicities of arsenic (As), cadmium (Cd), mercury (Hg), and lead (Pb), which are among the top eight toxic chemicals, were characterized at varying concentrations. MCF 7 cell lines were exposed to individual and composite mixtures containing the four metal ions in the proportion of their EPA's MCL for 24 hours, and the concentration-response data were generated spectrofluorometrically. Acute toxicities were estimated based on the uptake of fluorescence diacetate dye. Toxicological interactions among the four metals were profiled, based on computed interactive index. Results demonstrated that the toxicity of each of the metal ions was enhanced in the composite mixture, and the metals demonstrated differential interactions in a concentration dependent manner. Lead, the least toxic among the four metals, showed the highest enhancement (23-to 64-fold) in toxicity when in the mixture. Interaction among the four metals was largely additive although there was slight departures form additivity at the two extremes of the concentration range.
{"title":"Differential Toxicological Interaction among Arsenic, Cadmium, Lead, and Mercury on MCF 7 Cell Line","authors":"C. Klutse, K. Mack, K. Squibb, A. Ishaque","doi":"10.3814/2009/789636","DOIUrl":"https://doi.org/10.3814/2009/789636","url":null,"abstract":"Evaluation of joint toxic action of metal ion mixtures is one of the priority research areas due to the simultaneous occurrence of metals in the environment and the health risk they posed to humans and the environment as a mixture. Individual and composite mixture acute toxicities of arsenic (As), cadmium (Cd), mercury (Hg), and lead (Pb), which are among the top eight toxic chemicals, were characterized at varying concentrations. MCF 7 cell lines were exposed to individual and composite mixtures containing the four metal ions in the proportion of their EPA's MCL for 24 hours, and the concentration-response data were generated spectrofluorometrically. Acute toxicities were estimated based on the uptake of fluorescence diacetate dye. Toxicological interactions among the four metals were profiled, based on computed interactive index. Results demonstrated that the toxicity of each of the metal ions was enhanced in the composite mixture, and the metals demonstrated differential interactions in a concentration dependent manner. Lead, the least toxic among the four metals, showed the highest enhancement (23-to 64-fold) in toxicity when in the mixture. Interaction among the four metals was largely additive although there was slight departures form additivity at the two extremes of the concentration range.","PeriodicalId":169134,"journal":{"name":"Scholarly Research Exchange","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131366204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dietary factors influence carcinogenesis in a variety of tissues. The consumption of fruits and vegetables is associated with a decreased risk of several types of epithelial malignancies. In addition, there are interrelationships between diet, environmental factors, and genetics that can affect cancer risk. Potential chemopreventive agents against cancer development can be found among nutritive and/or nonnutritive compounds in inedible and edible plants. To identify potential cancer chemopreventive agents, scientists are evaluating hundreds of phytochemicals for the prevention of cancer. This short review article describes in vitro and in vivo assays reported to identify potential cancer preventive compounds from plants.
{"title":"Preclinical Assays for Identifying Cancer Chemopreventive Phytochemicals","authors":"T. Oyama, Y. Yasui, S. Sugie, Takuji Tanaka","doi":"10.3814/2009/475963","DOIUrl":"https://doi.org/10.3814/2009/475963","url":null,"abstract":"Dietary factors influence carcinogenesis in a variety of tissues. The consumption of fruits and vegetables is associated with a decreased risk of several types of epithelial malignancies. In addition, there are interrelationships between diet, environmental factors, and genetics that can affect cancer risk. Potential chemopreventive agents against cancer development can be found among nutritive and/or nonnutritive compounds in inedible and edible plants. To identify potential cancer chemopreventive agents, scientists are evaluating hundreds of phytochemicals for the prevention of cancer. This short review article describes in vitro and in vivo assays reported to identify potential cancer preventive compounds from plants.","PeriodicalId":169134,"journal":{"name":"Scholarly Research Exchange","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129798052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Longobardi, I. Pagano, U. Sisalli, Maurizio Foresti, V. Poddi
Background. Cemento-ossifying fibroma (COF) is a relatively rare tumor of the maxillary bones, classified among the fibro-osseous lesions Feller et al. (2004). The lesion that develops appears within the bone, although in some cases, it involves the soft tissues Kaufmann et al. (1999), Jung et al. (1999). In literature there is not report of COF in the thickness of the cheek. Methods. A 24-year-old Caucasian woman presented a hard mass of 1.5 cm in the thickness of the right cheek; no signs of damaged tissues were present. Radiographically all the mass appeared radiopaque as bone, and well demarcated with an evident capsule, without invasing the adjacent structures. The lesion was resected en bloc. Result. Pathological examination of the excised mass revealed an encapsulated cemento-ossifying fibroma that did not invade the adjacent tissues. The case was resolved with no complicance and with restitutio ad integrum. Conclusion. Typically, the unusual characterisitcs of a pathology get difficult as for its diagnosis and therapy. This is a case report of a rare cemento-ossifying fibroma of the cheek. Clinical and instrumental examinations exclude a malignant pathology and lead to an appropriate conservative surgical therapy. Only the histological examination confirmed the clinical diagnosis of extraosseous COF.
背景。骨水泥骨化纤维瘤(cemento - ossification纤维瘤，COF)是一种较为罕见的上颌骨肿瘤，Feller et al.(2004)将其归类为纤维骨性病变。病变出现在骨内，尽管在某些情况下，它涉及软组织Kaufmann et al. (1999)， Jung et al.(1999)。在文献中没有报道COF在脸颊的厚度。方法。24岁白人女性，右脸颊硬肿块，厚度1.5 cm;没有组织受损的迹象。x线片显示所有肿块像骨一样不透光，边界清晰，有明显的包膜，未侵犯邻近结构。病灶整体切除。结果。病理检查发现包被骨水泥骨化纤维瘤，未侵犯邻近组织。该案件在没有合规性的情况下得到了解决，并得到了赔偿和赔偿。结论。通常情况下，病理的不寻常特征使其诊断和治疗变得困难。这是一例罕见的骨水泥骨化纤维瘤的脸颊报告。临床和仪器检查排除恶性病理，导致适当的保守手术治疗。只有组织学检查证实了骨外COF的临床诊断。
{"title":"Extraosseous Cemento-Ossifying Fibroma of the Cheek","authors":"G. Longobardi, I. Pagano, U. Sisalli, Maurizio Foresti, V. Poddi","doi":"10.3814/2009/493190","DOIUrl":"https://doi.org/10.3814/2009/493190","url":null,"abstract":"Background. Cemento-ossifying fibroma (COF) is a relatively rare tumor of the maxillary bones, classified among the fibro-osseous lesions Feller et al. (2004). The lesion that develops appears within the bone, although in some cases, it involves the soft tissues Kaufmann et al. (1999), Jung et al. (1999). In literature there is not report of COF in the thickness of the cheek. Methods. A 24-year-old Caucasian woman presented a hard mass of 1.5 cm in the thickness of the right cheek; no signs of damaged tissues were present. Radiographically all the mass appeared radiopaque as bone, and well demarcated with an evident capsule, without invasing the adjacent structures. The lesion was resected en bloc. Result. Pathological examination of the excised mass revealed an encapsulated cemento-ossifying fibroma that did not invade the adjacent tissues. The case was resolved with no complicance and with restitutio ad integrum. Conclusion. Typically, the unusual characterisitcs of a pathology get difficult as for its diagnosis and therapy. This is a case report of a rare cemento-ossifying fibroma of the cheek. Clinical and instrumental examinations exclude a malignant pathology and lead to an appropriate conservative surgical therapy. Only the histological examination confirmed the clinical diagnosis of extraosseous COF.","PeriodicalId":169134,"journal":{"name":"Scholarly Research Exchange","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123068962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Lindboe, H. Brekke, Irina Schønhardt, Unn Houge
A 23-year-old man was operated for a skin tumor in the right axilla. Histological examination revealed findings consistent with a syringocystadenoma papilliferum. However, most of the papillary structures showed a disorganized proliferation of atypical cells without invasive growth, that is, a syringocystadenocarcinoma papilliferum in situ. Immunohistochemistry disclosed a different staining profile between the basal cells of the papillary structures and those of the columnar and atypical cells which reacted similarly. However, the atypical cells showed a stronger and more extensive expression of S-100 protein and CD56 than the columnar epithelium and a few of them also reacted with CEA. Ki-67 staining highlighted the increased proliferative activity of the atypical cells. The best antibody for depicting the basal cells was p63. In the present case immunohistochemistry was of little help to support the diagnosis of malignant transformation since the differences between the atypical and regular columnar cells were small and of a quantitative character only.
{"title":"Syringocystadenocarcinoma Papilliferum In Situ: Case Report with Immunohistochemical Observations","authors":"C. Lindboe, H. Brekke, Irina Schønhardt, Unn Houge","doi":"10.3814/2009/176837","DOIUrl":"https://doi.org/10.3814/2009/176837","url":null,"abstract":"A 23-year-old man was operated for a skin tumor in the right axilla. Histological examination revealed findings consistent with a syringocystadenoma papilliferum. However, most of the papillary structures showed a disorganized proliferation of atypical cells without invasive growth, that is, a syringocystadenocarcinoma papilliferum in situ. Immunohistochemistry disclosed a different staining profile between the basal cells of the papillary structures and those of the columnar and atypical cells which reacted similarly. However, the atypical cells showed a stronger and more extensive expression of S-100 protein and CD56 than the columnar epithelium and a few of them also reacted with CEA. Ki-67 staining highlighted the increased proliferative activity of the atypical cells. The best antibody for depicting the basal cells was p63. In the present case immunohistochemistry was of little help to support the diagnosis of malignant transformation since the differences between the atypical and regular columnar cells were small and of a quantitative character only.","PeriodicalId":169134,"journal":{"name":"Scholarly Research Exchange","volume":"140 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129016132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arthur Okere, D. Schwartz, P. Tierno, P. Schlievert, R. Hamadeh
We report a presentation in an adult with Streptococcus pyogenes bacteremia and invasive tissue disease with rhabdomyolysis, but without evidence of toxic shock syndrome or local myonecrosis. We thus investigated how this infecting strain differed from strains known to cause toxic shock syndrome.
{"title":"Severe Invasive Group A Streptococcal Disease with Rhabdomyolysis but without Evidence of Shock or Local Myositis","authors":"Arthur Okere, D. Schwartz, P. Tierno, P. Schlievert, R. Hamadeh","doi":"10.3814/2009/786451","DOIUrl":"https://doi.org/10.3814/2009/786451","url":null,"abstract":"We report a presentation in an adult with Streptococcus pyogenes bacteremia and invasive tissue disease with rhabdomyolysis, but without evidence of toxic shock syndrome or local myonecrosis. We thus investigated how this infecting strain differed from strains known to cause toxic shock syndrome.","PeriodicalId":169134,"journal":{"name":"Scholarly Research Exchange","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124867493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Naveed M. Natanzi, M. Amini, D. Yamini, S. Nielsen, R. Ram
Background and aim. Vasoactive intestinal peptide tumor is a rare neuroendocrine neoplasm which causes voluminous watery diarrhea via hypersecretion of electrolytes and water from the intestinal mucosa through a vasoactive intestinal peptide-mediated, cyclic AMP-dependent mechanism. The acid base imbalance generated by the loss of water and electrolytes leads to severe dehydration and potential renal failure, which can ultimately result in death if left untreated. This paper aims to review the clinical, histological, radiological, and diagnostic features of this disease as well as the therapeutic modalities in treating this condition. Methods. A review of literature was performed using MEDLINE, Pubmed, and Cochrane databases in collection of data using MeSH terms including vasoactive intestinal peptide, VIPoma, and WDHA. Results and conclusion. Vasoactive intestinal peptide tumor is a rare neoplasm associated with significant morbidity and mortality through secretion of water and electrolytes in the gastrointestinal tract. The nonspecific clinical presentation of this neoplasm can pose diagnostic challenges, as these tumors can be easily misdiagnosed as other conditions, ranging from laxative overdose to the presence of a carcinoid secreting tumor. Nevertheless, a number of imaging and laboratory studies can facilitate the correct evaluation and diagnosis of VIPoma. Following proper diagnosis, VIPomas are treated by either medical or surgical modalities depending on the existence and extent of metastasis.
{"title":"Vasoactive Intestinal Peptide Tumor","authors":"Naveed M. Natanzi, M. Amini, D. Yamini, S. Nielsen, R. Ram","doi":"10.3814/2009/938325","DOIUrl":"https://doi.org/10.3814/2009/938325","url":null,"abstract":"Background and aim. Vasoactive intestinal peptide tumor is a rare neuroendocrine neoplasm which causes voluminous watery diarrhea via hypersecretion of electrolytes and water from the intestinal mucosa through a vasoactive intestinal peptide-mediated, cyclic AMP-dependent mechanism. The acid base imbalance generated by the loss of water and electrolytes leads to severe dehydration and potential renal failure, which can ultimately result in death if left untreated. This paper aims to review the clinical, histological, radiological, and diagnostic features of this disease as well as the therapeutic modalities in treating this condition. \u0000Methods. A review of literature was performed using MEDLINE, Pubmed, and Cochrane databases in collection of data using MeSH terms including vasoactive intestinal peptide, VIPoma, and WDHA. \u0000Results and conclusion. Vasoactive intestinal peptide tumor is a rare neoplasm associated with significant morbidity and mortality through secretion of water and electrolytes in the gastrointestinal tract. The nonspecific clinical presentation of this neoplasm can pose diagnostic challenges, as these tumors can be easily misdiagnosed as other conditions, ranging from laxative overdose to the presence of a carcinoid secreting tumor. Nevertheless, a number of imaging and laboratory studies can facilitate the correct evaluation and diagnosis of VIPoma. Following proper diagnosis, VIPomas are treated by either medical or surgical modalities depending on the existence and extent of metastasis.","PeriodicalId":169134,"journal":{"name":"Scholarly Research Exchange","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121899864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Ballesteros, F. J. García-Lázaro, J. Moreno, Marta Chacón, Olivia Málaga, M. Lee
A case of bilateral compartment syndrome of the legs complicating prolonged spine surgery in the kneeling-90-90 position. Aggressive treatment of the reperfusion injury prevented severe rhabdomyolysis, acute renal failure, and sepsis, although it could not avoid the permanently disabling muscular necrosis. Close postoperative surveillance facilitate an early diagnosis and expedite appropriate treatment.
{"title":"Bilateral Leg Compartment Syndrome Complicating Prolonged Spine Surgery in the Kneeling Position","authors":"R. Ballesteros, F. J. García-Lázaro, J. Moreno, Marta Chacón, Olivia Málaga, M. Lee","doi":"10.3814/2009/535178","DOIUrl":"https://doi.org/10.3814/2009/535178","url":null,"abstract":"A case of bilateral compartment syndrome of the legs complicating \u0000 prolonged spine surgery in the kneeling-90-90 position. Aggressive treatment \u0000of the reperfusion injury prevented severe rhabdomyolysis, acute renal failure, \u0000and sepsis, although it could not avoid the permanently disabling muscular \u0000necrosis. Close postoperative surveillance facilitate an early diagnosis and expedite appropriate treatment.","PeriodicalId":169134,"journal":{"name":"Scholarly Research Exchange","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127126898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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