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Spatial and Racial/Ethnic Variation in the Prevalence of Cesarean Delivery in a South Carolina Medical Center. 南卡罗来纳州一家医疗中心剖腹产率的空间和种族/族裔差异。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-18 DOI: 10.1007/s40615-024-02218-3
Jeffrey T Howard, Sam Lawton, Dulaney Wilson, Amartha Gore, Latha Hebbar, Christine Morton, Christopher Goodier, Myrtede Alfred

Introduction: While racial/ethnic disparities in cesarean delivery have been noted in the literature, less is known about the intersection between individual-level race/ethnicity and community-level social vulnerability as factors in cesarean delivery. The goal was to use medical record data from a large medical center combined with census tract-level data to examine patterns of social vulnerability, racial population distribution, and prevalence of cesarean delivery.

Methods: Data were obtained from electronic medical records of patients from a large medical center in South Carolina from 2019 to 2020. The outcome variable was cesarean delivery (yes/no), and covariates included the year of delivery; age of patient; race/ethnicity; spoken language; BMI categories; clinical indications of anemia, hypertension, preeclampsia, and diabetes; and census tract Social Vulnerability Index (SVI). Generalized linear mixed models for multilevel binary logistic regression were used to test the main hypothesis that the census tract level Social Vulnerability Index is positively associated with cesarean delivery.

Results: Among a total of 5011 patients, we found that non-Hispanic Black mothers were more likely to have cesarean deliveries compared with non-Hispanic White mothers. After controlling for census tract-level SVI, the individual-level race/ethnicity association was no longer significant. Significant spatial autocorrelation across census tracts was evident for cesarean delivery prevalence, non-Hispanic Black population, and SVI. A high prevalence of cesarean delivery tended to cluster with high SVI and a high non-Hispanic Black population.

Conclusions: We found that non-Hispanic Black mothers were more likely to have cesarean deliveries, which was explained by census tract differences in the SVI.

导言:虽然剖腹产中的种族/民族差异已在文献中有所提及,但人们对个人层面的种族/民族与社区层面的社会脆弱性之间的交集作为剖腹产的影响因素却知之甚少。我们的目标是利用一家大型医疗中心的医疗记录数据与人口普查区数据相结合,研究社会脆弱性、种族人口分布和剖宫产发生率的模式:数据来自南卡罗来纳州一家大型医疗中心 2019 年至 2020 年期间的患者电子病历。结果变量为剖宫产(是/否),协变量包括分娩年份、患者年龄、种族/民族、口语、体重指数类别、贫血、高血压、子痫前期和糖尿病等临床指征以及人口普查区社会弱势指数(SVI)。研究采用多层次二元逻辑回归的广义线性混合模型来检验主要假设,即人口普查区一级的社会弱势指数与剖宫产呈正相关:在总共 5011 名患者中,我们发现与非西班牙裔白人母亲相比,非西班牙裔黑人母亲更有可能进行剖宫产。在控制了人口普查区层面的 SVI 后,个人层面的种族/族裔关联不再显著。剖宫产率、非西班牙裔黑人人口和 SVI 在不同人口普查区之间存在明显的空间自相关性。高剖腹产率往往与高 SVI 和高非西班牙裔黑人人口聚集在一起:我们发现,非西班牙裔黑人母亲更有可能进行剖宫产,这可以通过人口普查区的 SVI 差异来解释。
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引用次数: 0
"First, Trust Needs to Develop": Hematologists' Perspectives on Factors Influencing Black Persons' Participation in Clinical Trials. "首先,需要建立信任":血液学专家对影响黑人参与临床试验的因素的看法。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-18 DOI: 10.1007/s40615-024-02205-8
Shakira J Grant, Milenka Jean-Baptiste, Jiona A Mills, Paul Mihas

Background: Cancer clinical trials are crucial for treatment standards and innovation but lack racial-ethnic diversity. Understanding physician perspectives on recruiting participants is critical due to their role in decision-making about trial candidacy and enrollment.

Methods: From August 2021 to January 2022 we recruited 13 Academic hematologists experienced with treating blood cancers and enrolling clinical trial participants. Each hematologist participated in a 60-75-minute semistructured interview and completed a sociodemographic survey. Using the National Institute on Minority Health and Health Disparities multilevel model as a framework, we characterized hematologists' perceived barriers to clinical trial participation among Black persons. ATLAS.ti v9 and later v 23.2.1 was used for project management and to facilitate data analysis using the Sort and Sift, Think and Shift approach (ResearchTalk Inc).

Results: All hematologists were White, with 70% being male. Three factors influenced their perspectives on enrolling Black individuals in clinical trials: individual attitudes and beliefs, such as perceptions that Black or socioeconomically disadvantaged persons will be less willing or less compliant with the requirements for trial participation and follow-up. The need to build trusting relationships between themselves and patients prior to discussing clinical trials and the prevailing legacy of medical mistrust among the Black community. Trust was found to be the underlying factor in determining communication between hematologists and Black persons about clinical trials across all three levels.

Conclusion: This study highlights how hematologists' attitudes, beliefs, biases, and views on trust in patient relationships influence their communication with Black individuals about clinical trials. It emphasizes the need for further research to develop interventions that address the lack of racial and ethnic diversity in trials.

背景:癌症临床试验对治疗标准和创新至关重要,但缺乏种族-族裔多样性。由于医生在试验候选资格和入组决策中的作用,因此了解医生对招募参与者的观点至关重要:从 2021 年 8 月到 2022 年 1 月,我们招募了 13 名在治疗血癌和招募临床试验参与者方面经验丰富的学术血液科医生。每位血液病专家都参加了 60-75 分钟的半结构化访谈,并完成了一份社会人口调查。我们以美国国家少数族裔健康和健康差异研究所的多层次模型为框架,描述了血液病专家对黑人参与临床试验的障碍的看法。我们使用 ATLAS.ti v9 及以后的 23.2.1 版进行项目管理,并使用排序与筛选、思考与转换方法(ResearchTalk Inc)促进数据分析:所有血液学专家均为白人,其中 70% 为男性。有三个因素影响了他们对黑人参与临床试验的看法:个人态度和信念,如认为黑人或社会经济条件较差的人会不太愿意或不太遵守参与试验和随访的要求。在讨论临床试验之前,需要在自己和患者之间建立信任关系,以及黑人群体中普遍存在的对医学的不信任。研究发现,信任是决定血液科医生与黑人就临床试验在所有三个层面上进行沟通的根本因素:本研究强调了血液科医生的态度、信念、偏见以及对患者关系中信任的看法如何影响他们与黑人就临床试验进行沟通。它强调了进一步研究开发干预措施的必要性,以解决试验中缺乏种族和民族多样性的问题。
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引用次数: 0
Barriers and Facilitators to the Success of Black Academic Physicians. 黑人学术医生成功的障碍和促进因素。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-17 DOI: 10.1007/s40615-024-02201-y
Barbara Jerome, Magali Fassiotto, Yvonne Bonnie Maldonado, Tamara Dunn

Despite efforts to recruit and retain Black physicians, Black individuals continue to be underrepresented in medicine in the USA. Although numerous studies have investigated the experiences of academic physicians from racial/ethnic backgrounds underrepresented in medicine, the experience of Black academic physicians, who may face additional unique challenges, remains underinvestigated. Using a qualitative research design, we investigate barriers to and facilitators of success and well-being of Black faculty at one academic medical center through interviews of 30 Black faculty members. Overall, ten themes emerged as barriers or facilitators to faculty success and well-being. Significant barriers include continued lack of representation; devaluing of research in community health and health disparities, as well as other diversity-related activities; and both overt and implicit discrimination, which contribute to feelings of isolation and disrespect. Facilitators include having a community to maintain sense of belonging, financial support for health disparities and diversity-related contributions, and collaboration with peers. Good mentorship and sponsorship as well as an institutional culture that supports inclusion can play significant roles as facilitators, whereas the lack of these factors can present substantial barriers. Institutional policies and external socio-political factors have a major influence on both the barriers and facilitators to the success and well-being of Black faculty. Our study has put a clearer focus on barriers that are unique to or more pronounced among Black faculty and the facilitators that may serve to mitigate these barriers. These findings can inform the design of interventions to recruit and retain Black faculty in medicine.

尽管美国努力招募和留住黑人医生,但黑人在医学界的代表性仍然不足。尽管有许多研究调查了来自医学领域代表性不足的种族/民族背景的学术医生的经历,但对可能面临更多独特挑战的黑人学术医生的经历的调查仍然不足。我们采用定性研究设计,通过对 30 名黑人教职员工进行访谈,调查了一家学术医学中心黑人教职员工成功和幸福的障碍和促进因素。总体而言,有十个主题成为教职员工成功和幸福的障碍或促进因素。重大障碍包括持续缺乏代表性;贬低社区健康和健康差异方面的研究以及其他与多样性相关的活动;公开和隐含的歧视,这些都造成了孤立感和不被尊重感。促进因素包括拥有一个可以保持归属感的社区、对健康差异和多样性相关贡献的财政支持以及与同行的合作。良好的指导和赞助以及支持包容的机构文化可以发挥重要的促进作用,而缺乏这些因素则会造成巨大的障碍。机构政策和外部社会政治因素对黑人教职员工的成功和福祉的障碍和促进因素都有重大影响。我们的研究更加明确地聚焦于黑人教职员工所特有的或更加明显的障碍,以及可能有助于减轻这些障碍的促进因素。这些发现可以为设计干预措施,招聘和留住医学界的黑人教师提供参考。
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引用次数: 0
The Longitudinal Impact of Family, Religious, and School Support on the Mental Health of Filipino and Korean American Youth Across Adolescence. 家庭、宗教和学校支持对菲律宾裔和韩裔美国青少年青春期心理健康的纵向影响》(The Longitudinal Impact of Family, Religious, and School Support on the Mental Health of Filipino and Korean American Youth Across Adolescence)。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-16 DOI: 10.1007/s40615-024-02200-z
Michael Park, In Young Park, Yoonsun Choi, Julia R Henly

Asian Americans, currently the most rapidly expanding racial group in the USA, are experiencing persistent mental health inequities. These inequities are particularly pronounced during adolescence, highlighting the critical need for dedicated focus on this demographic. Social support is a key shield against mental distress among these adolescents, yet little research has examined the collective impact of multiple sources of support over time, across developmental stages, and for different ethnic subgroups. Drawing on the integrated conceptual framework, this longitudinal study is the first to our knowledge to examine how support from families, religious organizations, and schools together predicts mental health over time across adolescents' developmental stages. We further examined how these relationships may be moderated by age groups, distinguishing between the early adolescence cohort and the middle adolescence cohort. Data were from the Midwest Longitudinal Study of Asian American Families (MLSAAF) project that survey-interviewed 378 Filipino American and 408 Korean American adolescents (Mage = 15 years). Findings reveal that family support consistently buffers against mental distress throughout adolescence for both groups. Religious support distinctly aids Filipino American early adolescents, while school support notably benefits early adolescents regardless of ethnicity. These findings emphasize the universal protective effects of social support, while also highlighting the nuanced ways that developmental stage and ethnicity may influence how different sources of support impact mental health. This underscores the need for developmentally and culturally sensitive mental health strategies for Asian American adolescents.

亚裔美国人是目前美国人口增长最迅速的种族群体,但他们的心理健康却长期处于不平等状态。这些不平等现象在青少年时期尤为明显,这也凸显了对这一人群进行专门关注的迫切需要。在这些青少年中,社会支持是抵御心理困扰的重要屏障,但很少有研究对不同时期、不同发展阶段以及不同种族亚群的多种支持来源的集体影响进行研究。根据综合概念框架,这项纵向研究是我们所知的第一项研究,它考察了家庭、宗教组织和学校的支持如何共同预测青少年在不同成长阶段的心理健康。我们还进一步研究了这些关系如何受到年龄组的调节,并区分了青春期早期组群和青春期中期组群。数据来自中西部亚裔美国人家庭纵向研究(MLSAAF)项目,该项目调查访问了 378 名菲律宾裔美国青少年和 408 名韩裔美国青少年(年龄 = 15 岁)。研究结果表明,家庭的支持对这两个群体的青少年在整个青春期的精神压力都有持续的缓冲作用。宗教支持对菲律宾裔美国青少年有明显的帮助,而学校支持对不同种族的青少年都有显著的益处。这些发现强调了社会支持的普遍保护作用,同时也强调了发展阶段和种族可能对不同支持来源影响心理健康的细微方式。这强调了针对亚裔青少年的发展和文化敏感性心理健康策略的必要性。
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引用次数: 0
Climate Change, Racism, and Food Insecurity: Cyclical Impacts of Stressors Exacerbate Health Disparities. 气候变化、种族主义和粮食不安全:压力的周期性影响加剧了健康差异。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-16 DOI: 10.1007/s40615-024-02202-x
Christina Ek, James R Hébert, Daniela B Friedman, Dwayne E Porter

Introduction: Disadvantaged populations have higher rates of chronic disease, including heart disease, cancer, and diabetes. Race, ethnicity, lower socioeconomic status, and poverty all contribute to these disproportionate rates. Other factors, including systemic racism, climate change, poor diet, lack of food access, and epigenetic influences, that are distributed and experienced differently across vulnerable populations also play a significant role in the development of chronic diseases. This comprehensive review of contributors to chronic diseases emphasizes a unique focus on these identified emerging factors.

Methods: An ad hoc literature review using OVID Medline and Web of Science was conducted.

Results: Findings from prior studies indicate that multiple stressors, both in isolation and in combination, and their negative impacts on both physical and mental health of minorities are exacerbated by climate change.

Discussion: Various stressors dramatically increase chronic disease risk in minority groups. Recommendations for future research to elucidate the impacts of climatic, racial, and dietary adversity with minority populations are presented. Further study in this area is critical for achieving the UN Sustainable Development Goals and improving public health outcomes.

导言:弱势群体的慢性病发病率较高,包括心脏病、癌症和糖尿病。种族、民族、较低的社会经济地位和贫困都是导致这些疾病发生率过高的原因。其他因素,包括系统性种族主义、气候变化、不良饮食习惯、缺乏食物获取途径和表观遗传影响,在弱势人群中的分布和经历不同,也对慢性病的发展起着重要作用。这篇关于慢性病诱因的综合综述强调了对这些已发现的新因素的独特关注:方法:使用 OVID Medline 和 Web of Science 进行了特别文献综述:结果:先前的研究结果表明,气候变化加剧了多种压力因素(包括单独压力因素和综合压力因素)及其对少数群体身心健康的负面影响:讨论:各种压力因素大大增加了少数群体患慢性疾病的风险。本文提出了未来研究的建议,以阐明气候、种族和饮食逆境对少数群体的影响。该领域的进一步研究对于实现联合国可持续发展目标和改善公共卫生成果至关重要。
{"title":"Climate Change, Racism, and Food Insecurity: Cyclical Impacts of Stressors Exacerbate Health Disparities.","authors":"Christina Ek, James R Hébert, Daniela B Friedman, Dwayne E Porter","doi":"10.1007/s40615-024-02202-x","DOIUrl":"https://doi.org/10.1007/s40615-024-02202-x","url":null,"abstract":"<p><strong>Introduction: </strong>Disadvantaged populations have higher rates of chronic disease, including heart disease, cancer, and diabetes. Race, ethnicity, lower socioeconomic status, and poverty all contribute to these disproportionate rates. Other factors, including systemic racism, climate change, poor diet, lack of food access, and epigenetic influences, that are distributed and experienced differently across vulnerable populations also play a significant role in the development of chronic diseases. This comprehensive review of contributors to chronic diseases emphasizes a unique focus on these identified emerging factors.</p><p><strong>Methods: </strong>An ad hoc literature review using OVID Medline and Web of Science was conducted.</p><p><strong>Results: </strong>Findings from prior studies indicate that multiple stressors, both in isolation and in combination, and their negative impacts on both physical and mental health of minorities are exacerbated by climate change.</p><p><strong>Discussion: </strong>Various stressors dramatically increase chronic disease risk in minority groups. Recommendations for future research to elucidate the impacts of climatic, racial, and dietary adversity with minority populations are presented. Further study in this area is critical for achieving the UN Sustainable Development Goals and improving public health outcomes.</p>","PeriodicalId":16921,"journal":{"name":"Journal of Racial and Ethnic Health Disparities","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Handoffs and Equity: Impact of a Patient Distribution Model on Handoffs for Black Patients. 交接与公平:病人分配模式对黑人病人交接的影响。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-15 DOI: 10.1007/s40615-024-02196-6
Ethan Molitch-Hou, Thomas J Best, Ellis Green, Khanh T Nguyen, Grace LaShore, Matthew T Cerasale

Background: Hospital medicine patient distribution models (PDM) assign patients to inpatient services on hospital admission. Models balance tradeoffs including patient handoffs, physician wellness, subspecialty care, and other factors to ensure optimal outcomes; however, equity is rarely considered. Handoffs during inpatient care can result in medical error and worse patient outcomes. This study evaluates the impact of a PDM that prioritizes use of specialty care services and an overflow service (OS) during high census on racial inequities in handoff frequency.

Methods: A single-center retrospective cohort study of inpatient encounters on hospital medicine services from July 2017 to December 2019 was conducted. The primary exposures included being discharged by a general medicine service (GMS) or cared for by an OS. The primary outcome was handoffs per day of stay, analyzed by multivariable regression adjusted for age, gender, race, ethnicity, insurance, discharge from GMS, and care from OS.

Results: A total of 4165 inpatient hospitalizations with the majority of their stay on a hospital medicine service were reviewed. Patients discharged by GMS (78.2% vs. 58.1%, p < .001) and cared for by OS (78.7% vs. 67.0%, p < .001) were more likely to identify as Black. Multivariable analysis showed a handoff risk ratio of 1.53 (p < .001) for OS patients and 1.06 (p = .01) if discharged from GMS, but race alone did not significantly affect risk of handoffs.

Conclusion: The PDM prioritization drove increased handoffs disproportionately for Black patients. Multivariable analysis showed that race alone did not contribute to increased handoffs suggesting the creation of a systemic bias in patient care.

背景:医院医学病人分配模式(PDM)在病人入院时为其分配住院服务。该模型平衡了各种权衡因素,其中包括病人交接、医生健康、亚专科护理和其他因素,以确保最佳治疗效果;但很少考虑公平性。住院治疗期间的交接班可能会导致医疗失误和更糟糕的患者预后。本研究评估了优先使用专科护理服务的 PDM 和高人口密度时的分流服务(OS)对移交频率种族不平等的影响:对 2017 年 7 月至 2019 年 12 月期间医院医疗服务的住院病人就诊情况进行了单中心回顾性队列研究。主要暴露包括由普通内科服务(GMS)出院或由操作系统护理。主要结果是住院期间每天的交接,通过多变量回归进行分析,并对年龄、性别、种族、民族、保险、GMS出院和OS护理进行调整:共审查了 4165 名住院病人,其中大部分住院时间是在医院医疗服务部门度过的。由 GMS 出院的患者占 78.2%,由 OS 出院的患者占 58.1%:PDM 优先排序导致黑人患者的出院率不成比例地上升。多变量分析表明,种族本身并不会导致交接率增加,这表明在患者护理中存在系统性偏差。
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引用次数: 0
A Pilot Study Exploring the Feasibility of Virtual Written Exposure Therapy with Underserved Black Perinatal Women. 探索虚拟书面暴露疗法对缺乏服务的黑人围产期妇女可行性的试点研究。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-14 DOI: 10.1007/s40615-024-02203-w
Angela Neal-Barnett, Robert E Stadulis, Eniolufolake E Ayoade, Alexis McGhee-Dinvaut

In the USA, Black pregnant women are at the highest risk for maternal morbidity. They also experience the highest rates of trauma exposure and posttraumatic stress disorder (PTSD). PTSD takes a toll on Black women's mental and physical health, placing them at risk for maternal morbidity. It increases several mental health symptoms such as suicidality, anxiety, re-living the trauma, and numbness. These mental health conditions adversely affect health behaviors, including those essential for maternal health, such as attending prenatal and postpartum appointments. Furthermore, untreated PTSD is associated with higher blood pressure, increasing Black mothers' risk of pre-eclampsia. For a variety of reasons including cultural mistrust, stigma, transportation, time constraints, and access to care, PTSD is frequently underassessed and undertreated among Black perinatal women. Written exposure therapy (WET) is a state-of-the-art brief treatment for PTSD. In this study, we explored the initial feasibility of the virtual delivery of WET to reduce PTSD symptoms among Black perinatal women. Results found the virtual delivery of WET to be feasible. Symptom reduction for PTSD in participants was 50-100% during follow-up, suggesting potential effectiveness of the intervention. Implications for virtual delivery of WET in reducing risk for Black maternal morbidity are discussed.

在美国,黑人孕妇是产妇发病风险最高的群体。她们遭受创伤和创伤后应激障碍(PTSD)的比例也最高。创伤后应激障碍会损害黑人妇女的身心健康,使她们面临孕产妇发病风险。创伤后应激障碍会增加多种心理健康症状,如自杀、焦虑、重新经历创伤和麻木。这些心理健康问题会对健康行为产生不利影响,包括那些对产妇健康至关重要的行为,例如产前和产后就诊。此外,未经治疗的创伤后应激障碍与血压升高有关,增加了黑人母亲患先兆子痫的风险。由于文化不信任、耻辱感、交通、时间限制和就医途径等各种原因,黑人围产期妇女的创伤后应激障碍常常得不到充分评估和治疗。书面暴露疗法(WET)是治疗创伤后应激障碍的最先进的简短疗法。在这项研究中,我们探讨了虚拟 WET 在减少黑人围产期妇女创伤后应激障碍症状方面的初步可行性。结果发现,WET 虚拟疗法是可行的。在随访期间,参与者的创伤后应激障碍症状减少了 50%-100%,这表明该干预措施具有潜在的有效性。本文讨论了虚拟 WET 在降低黑人孕产妇发病风险方面的意义。
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引用次数: 0
Ethnic-Specific Threshold Analysis and BMI and Waist Circumference Cutoffs for Cardiovascular Disease and Subjective Wellbeing: Results using Data from the UK Biobank. 针对心血管疾病和主观幸福感的特定种族阈值分析及体重指数和腰围临界值:使用英国生物库数据得出的结果。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-11 DOI: 10.1007/s40615-024-02193-9
Mubarak Patel, Mohammed Aadil Buchya, Olalekan Uthman

Objectives: We aimed to identify ethnicity-specific BMI and waist circumference cutoffs for cardiovascular disease (CVD) and to define optimal thresholds for CVD risk and subjective wellbeing (SWB) through predictive modelling, to inform precise public health initiatives.

Methods: We used data from 296,767 UK Biobank participants and adjusted logistic and linear regression models for CVD and SWB, respectively, complemented by receiver operating characteristic analysis, to explore optimal risk thresholds of CVD in six different ethnic groups and to calculate ethnicity-specific cutoffs of BMI and waist circumference (WC) to further elucidate the relationships between demographic factors and cardiovascular risk among diverse populations.

Results: The logistic regression model of CVD revealed moderate discriminative ability (AUROC ~ 64-65%) across ethnicities for CVD status, with sensitivity and specificity values indicating the model's predictive accuracy. For SWB, the model demonstrated moderate performance with an AUROC of 63%, supported by significant variables that included age, BMI, WC, physical activity, and alcohol intake. Adjusted-incidence rates of CVD revealed the evidence ethnic-specific CVD risk profiles with Whites, South Asians and Blacks demonstrating higher predicted CVD events compared to East Asians, mixed and other ethnic groups.

Conclusion: Alterations of ethnicity-specific BMI and waist circumference are required to ensure ethnic minorities are provided with proper mitigation of cardiovascular risk, addressing the disparities observed in CVD prevalence and outcomes across diverse populations. This tailored approach to risk assessment can facilitate early detection, intervention and management of CVD, ultimately improving health outcomes and promoting health equity. The moderate accuracy of predictive models underscores the need for further research to identify additional variables that may enhance predictive accuracy and refine risk assessment strategies.

目标:我们旨在确定特定种族的心血管疾病(CVD)BMI 和腰围临界值,并通过预测建模确定心血管疾病风险和主观幸福感(SWB)的最佳阈值,为精确的公共卫生措施提供信息:我们利用 296,767 名英国生物库参与者的数据,分别针对心血管疾病和主观幸福感建立了调整后的逻辑回归模型和线性回归模型,并辅以接受者操作特征分析,以探索六个不同种族群体的最佳心血管疾病风险阈值,并计算出特定种族的体重指数和腰围临界值,从而进一步阐明不同人群中人口因素与心血管疾病风险之间的关系:心血管疾病的逻辑回归模型显示了不同种族对心血管疾病状态的中等辨别能力(AUROC ~ 64-65%),灵敏度和特异性值显示了模型的预测准确性。就腰围而言,该模型表现中等,AUROC 为 63%,得到了年龄、体重指数(BMI)、腹围、体力活动和酒精摄入量等重要变量的支持。调整后的心血管疾病发病率显示了特定种族的心血管疾病风险特征,与东亚人、混血人和其他种族相比,白人、南亚人和黑人的预测心血管疾病发病率更高:结论:需要改变特定种族的体重指数和腰围,以确保为少数民族提供适当的心血管风险缓解措施,解决在不同人群中观察到的心血管疾病发病率和结果差异。这种量身定制的风险评估方法可促进心血管疾病的早期发现、干预和管理,最终改善健康结果并促进健康公平。预测模型的准确性一般,这强调了进一步研究的必要性,以确定可提高预测准确性和完善风险评估策略的其他变量。
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引用次数: 0
COVID-19 Deaths and Minority Health Social Vulnerability, in the U.S., January 1, 2020 through June 24, 2023. COVID-19 2020 年 1 月 1 日至 2023 年 6 月 24 日美国的死亡人数和少数民族健康社会脆弱性。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-11 DOI: 10.1007/s40615-024-02192-w
Hope King, Makhabele Nolana Woolfork, Andrea Yunyou, Yuwa Edomwande, Erik Euler, Olivia Almendares, Suresh Nath Neupane, Melissa Briggs Hagen

Background: Health disparities, leading to worse health outcomes such as elevated COVID-19 mortality rates, are rooted in social and structural factors. These disparities notably impact individuals from lower socioeconomic backgrounds and more socially vulnerable areas. We analyzed the relationship between COVID-19 deaths and social vulnerability using the Minority Health Social Vulnerability Index (MHSVI).

Methods: COVID-19 death data in the U.S. was obtained from the Centers for Disease Control and Prevention (CDC) National Center for Health Statistics, where COVID-19 deaths were defined using the ICD-10 code U07.1. MHSVI composite scores were calculated for 3089 U.S. counties and categorized into social vulnerability quartiles, where values ranged from 0 (lowest vulnerability) to 1 (highest vulnerability). Negative binomial regression was employed to determine death rate ratios for each quartile within each theme. Finally, a multivariate negative binomial regression including all MHSVI sub-themes, excluding the overall index ranking, was used to assess the association between each theme and COVID-19 death rates independently.

Results: There were 1,134,272 COVID-19 deaths from January 1, 2020 through June 24, 2023. Adjusted rate ratios for COVID-19 deaths in the overall index ranking were 1.06 (95% CI 0.99-1.13), 1.14 (95% CI 1.06-1.22), and 1.41 (95% CI 1.31-1.52) for the second, third and fourth quartiles, respectively. Sub-themes of socioeconomic status (SES), household characteristics (HC), racial and ethnic minority status (REMS), housing type and transportation (HTT), and medical vulnerability (MV) revealed increasing death rates in higher vulnerability quartiles. The healthcare infrastructure and access (HIA) theme had decreasing death rate ratios of 0.74 (95% CI 0.71-0.78), 0.59 (95% CI 0.56-0.62), and 0.42 (95% CI 0.39-0.44) for the second, third, and fourth quartiles, respectively. Finally, the multivariate analysis showed that the HC, HTT, HIA, and MV themes were associated with COVID-19 deaths (P < 0.05).

Conclusion: Counties that were identified as more socially vulnerable experienced higher death rates from COVID-19. These areas may need additional public health and social support during future pandemics.

背景:健康差异会导致更糟糕的健康结果,如 COVID-19 死亡率升高,其根源在于社会和结构性因素。这些差异对社会经济背景较差和社会弱势地区的人影响显著。我们使用少数民族健康社会脆弱性指数(MHSVI)分析了 COVID-19 死亡与社会脆弱性之间的关系:美国 COVID-19 死亡数据来自美国疾病控制和预防中心 (CDC) 国家卫生统计中心,其中 COVID-19 死亡使用 ICD-10 代码 U07.1 进行定义。计算了美国 3089 个县的 MHSVI 综合得分,并将其划分为社会脆弱性四分位数,数值从 0(最低脆弱性)到 1(最高脆弱性)不等。采用负二叉回归法确定每个主题中每个四分位数的死亡率比率。最后,使用包括所有 MHSVI 子主题(不包括总指数排名)的多变量负二项回归来独立评估每个主题与 COVID-19 死亡率之间的关联:从 2020 年 1 月 1 日到 2023 年 6 月 24 日,共有 1,134,272 例 COVID-19 死亡。在总指数排名中,第二、第三和第四四分位数的 COVID-19 死亡调整率比分别为 1.06(95% CI 0.99-1.13)、1.14(95% CI 1.06-1.22)和 1.41(95% CI 1.31-1.52)。社会经济状况(SES)、家庭特征(HC)、少数种族和少数民族状况(REMS)、住房类型和交通(HTT)以及医疗脆弱性(MV)等子主题显示,在较高的脆弱性四分位数中,死亡率不断上升。医疗基础设施和获取(HIA)主题在第二、第三和第四四分位数的死亡率比率分别为 0.74(95% CI 0.71-0.78)、0.59(95% CI 0.56-0.62)和 0.42(95% CI 0.39-0.44)。最后,多变量分析表明,HC、HTT、HIA 和 MV 主题与 COVID-19 死亡相关(P 结论):被确定为社会脆弱性较高的县的 COVID-19 死亡率较高。在未来的大流行病期间,这些地区可能需要更多的公共卫生和社会支持。
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引用次数: 0
Chronic Physiological Dysregulation and Changes in Depressive Symptoms: Testing Sex and Race as Vulnerability Factors. 慢性生理失调与抑郁症状的变化:将性别和种族作为易感因素进行测试
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-10 DOI: 10.1007/s40615-024-02189-5
Stacey N Doan, Alexandra S Aringer, Jessica M Vicman, Thomas Fuller-Rowell

Depression is a growing public health concern that affects approximately 5% of adults in their lifetime (WHO in Depression, 2021). Understanding the biological correlates of depression is imperative for advancing treatment. Of particular interest is allostatic load, a multisystem indicator of chronic physiological dysregulation (McEwen and Seeman in, Ann N Y Acad Sci, 1999). The current longitudinal study examined the association between allostatic load, depressive symptoms, and the moderating roles of sex and race. Participants consisted of 150 young adults (Mage = 18.81) who reported their demographics and depressive symptoms at T1 and T2, a year and a half later. Allostatic load was computed using indicators of metabolic, cardiovascular, and neuroendocrine functioning. Allostatic load was found to predict changes in depressive symptoms. Moreover, interaction effects models revealed that the associations between allostatic load and depressive symptoms at follow-up were further influenced by sex, such that the relationship was significant for males, with pronounced effects for Black males in particular. Black males may be particularly vulnerable to the mental health consequences of biological dysregulation.

抑郁症是一个日益严重的公共健康问题,一生中约有 5%的成年人会受到抑郁症的影响(世界卫生组织《抑郁症》,2021 年)。了解抑郁症的生物学相关因素对于促进治疗至关重要。尤其值得关注的是静态负荷,它是慢性生理失调的多系统指标(McEwen 和 Seeman,1999 年纽约科学院学报)。目前的纵向研究考察了异位负荷、抑郁症状之间的关联,以及性别和种族的调节作用。研究对象包括 150 名年轻人(平均年龄为 18.81 岁),他们在一年半后的第一阶段和第二阶段报告了自己的人口统计数据和抑郁症状。研究人员利用代谢、心血管和神经内分泌功能指标计算了静态负荷。结果发现,代谢负荷可预测抑郁症状的变化。此外,交互效应模型显示,代谢负荷与随访抑郁症状之间的关系受性别的进一步影响,因此男性的代谢负荷与抑郁症状之间的关系显著,尤其是对黑人男性的影响更为明显。黑人男性可能特别容易受到生物失调对心理健康的影响。
{"title":"Chronic Physiological Dysregulation and Changes in Depressive Symptoms: Testing Sex and Race as Vulnerability Factors.","authors":"Stacey N Doan, Alexandra S Aringer, Jessica M Vicman, Thomas Fuller-Rowell","doi":"10.1007/s40615-024-02189-5","DOIUrl":"https://doi.org/10.1007/s40615-024-02189-5","url":null,"abstract":"<p><p>Depression is a growing public health concern that affects approximately 5% of adults in their lifetime (WHO in Depression, 2021). Understanding the biological correlates of depression is imperative for advancing treatment. Of particular interest is allostatic load, a multisystem indicator of chronic physiological dysregulation (McEwen and Seeman in, Ann N Y Acad Sci, 1999). The current longitudinal study examined the association between allostatic load, depressive symptoms, and the moderating roles of sex and race. Participants consisted of 150 young adults (M<sub>age</sub> = 18.81) who reported their demographics and depressive symptoms at T1 and T2, a year and a half later. Allostatic load was computed using indicators of metabolic, cardiovascular, and neuroendocrine functioning. Allostatic load was found to predict changes in depressive symptoms. Moreover, interaction effects models revealed that the associations between allostatic load and depressive symptoms at follow-up were further influenced by sex, such that the relationship was significant for males, with pronounced effects for Black males in particular. Black males may be particularly vulnerable to the mental health consequences of biological dysregulation.</p>","PeriodicalId":16921,"journal":{"name":"Journal of Racial and Ethnic Health Disparities","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Racial and Ethnic Health Disparities
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