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Assessing Non-Oral PrEP Alternatives Among Young Black Women in the Southern USA. 评估非口服PrEP替代方案在美国南部的年轻黑人妇女。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-06 DOI: 10.1007/s40615-024-02263-y
Damian J Denson, Casey Langer Tesfaye, Daniela Glusberg, Alisú Schoua-Glusberg, Valerie Betley, Bryan Gale, Jessica Cardo, Paula M Frew, Eleanor McLellan-Lemal, Siobhán M O'Connor, Janet M McNicholl

Young Black women in the southern US face a high HIV burden. While daily oral HIV pre-exposure prophylaxis (PrEP) can effectively prevent HIV, its use is low among Black women. The acceptability of and perceived intention to use emerging PrEP products among young Black women in the southern US are not well understood. Non-oral PrEP alternatives could address challenges to PrEP uptake and reduce health disparities. We conducted virtual semi-structured interviews with Black women aged 18-34 in Atlanta, GA; Baton Rouge, LA; and Jackson, MS, to explore their perspectives on three emerging PrEP products: a long-acting injection, a subdermal implant, and a dual-purpose contraception and HIV prevention intravaginal ring. Seventy-five interviews were conducted from January to October 2021 and analyzed using inductive thematic analysis with NVivo software. Most participants were open to using medication to prevent HIV. The intravaginal ring was the most preferred, primarily due to its dual-purpose function, although it was also frequently rejected. The long-acting injection was the second most preferred and least rejected, perceived as the least invasive. The skin implant was the least preferred and most rejected, viewed as the most invasive. Our findings highlight the need for multiple PrEP options to meet individual preferences. Detailed descriptions, instructions, and experiential learning methods are crucial for choosing non-oral PrEP modalities. Practitioners should address questions and offer peer-based learning opportunities. Designing and promoting PrEP strategies for young Black women should involve close consultation with these consumers.

美国南部的年轻黑人女性面临着很高的艾滋病负担。虽然每日口服HIV暴露前预防(PrEP)可以有效预防HIV,但黑人妇女的使用率很低。美国南部年轻黑人女性对新兴PrEP产品的接受程度和使用意向尚不清楚。非口服PrEP替代品可以解决PrEP吸收的挑战并减少健康差距。我们对佐治亚州亚特兰大市18-34岁的黑人女性进行了虚拟半结构化访谈;巴吞鲁日,洛杉矶;和Jackson, MS,探讨他们对三种新兴PrEP产品的看法:长效注射,皮下植入,以及双重用途避孕和HIV预防阴道内环。从2021年1月到10月进行了75次访谈,使用NVivo软件进行归纳主题分析。大多数参与者对使用药物预防艾滋病毒持开放态度。阴道内环是最受欢迎的,主要是由于它的双重功能,尽管它也经常被拒绝。长效注射是第二种最受欢迎和最不被拒绝的注射方式,被认为是侵入性最小的。皮肤植入是最不受欢迎和最拒绝的,被认为是最具侵入性的。我们的研究结果强调需要多种PrEP选择来满足个人偏好。详细的描述、指导和体验式学习方法对于选择非口服PrEP模式至关重要。从业者应该解决问题并提供基于同行的学习机会。为年轻黑人妇女设计和推广预防PrEP策略应与这些消费者密切协商。
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引用次数: 0
Associating Race, Income, and Discrimination with COVID-19 Vaccine Status, Hesitancy, and Access in the United States: A Cross-sectional Study. 在美国,将种族、收入和歧视与COVID-19疫苗状况、犹豫和获取联系起来:一项横断面研究
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-06 DOI: 10.1007/s40615-024-02282-9
Rachel E Dinero, Brittany L Kmush

There is an emerging literature exploring the role of discrimination in vaccine hesitancy, particularly among Black individuals. The goal of the present research is to explore how COVID-19 vaccine hesitancy, vaccine status, and vaccine access are associated with race, income, and discrimination. A quota sample of 798 Black/White and low/high income participants from the United States completed an online survey between March 8 and April 19, 2023. The survey assessed self-reported race, income, discrimination, vaccine hesitancy, and vaccine access. Perceived discrimination (B = .15, P = .002) and being Black (B = -.30, P < .001) were associated with higher vaccine hesitancy. Lower income White participants were less likely to be vaccinated than Black or higher income White participants (PR = .66, P = .04). The lowest vaccine access was reported by low-income White participants with high levels of discrimination and the highest access was reported by high-income Black participants with low levels of discrimination (B = -.03, P = .05). Our findings highlight the unique impact of discrimination on vaccine access and vaccine hesitancy. Further, despite previous literature identifying Black populations as having lower vaccine access, our findings suggest that lower income White participants reported the lowest vaccine access and were the least likely to be vaccinated. These findings have implications for understanding the impact of discrimination on vaccine-related beliefs and behaviors, which can inform vaccine-related communication in communities where discrimination is likely.

有一个新兴的文献探讨歧视在疫苗犹豫中的作用,特别是在黑人中。本研究的目的是探讨COVID-19疫苗犹豫、疫苗状况和疫苗获取与种族、收入和歧视之间的关系。2023年3月8日至4月19日期间,来自美国的798名黑人/白人和低收入/高收入参与者完成了一项在线调查。该调查评估了自我报告的种族、收入、歧视、疫苗犹豫和疫苗获取情况。感知到的歧视(B =。15, P = .002)和黑人(B = -)。30日,警
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引用次数: 0
A Systematic Review of the Influence of Social Determinants of Health on Mental Health Service Utilization and Outcomes Among Asian American Cancer Survivors. 健康社会决定因素对亚裔美国癌症幸存者心理健康服务利用和结果影响的系统综述
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-03 DOI: 10.1007/s40615-024-02275-8
Yi-Ping Wen, Eden R Brauer, Kristen Choi

Objective: The purpose of this review was to identify relationships between social determinants of mental health service utilization and outcomes among Asian American cancer survivors in the United States (U.S.).

Methods: We performed a systematic literature search in PubMed, PsycINFO, CINAHL, and Embase for peer-reviewed studies between January 2000 and May 2024. Based on the Healthy People 2023 framework, social determinants of health (SDOH) were categorized into five SDOH domains. We extracted data using a table of evidence, and we assessed study quality using the Johns Hopkins Evidence-Based Practice.

Results: Ten non-experimental studies, with either "High" or "Good" quality, met eligibility criteria. Two examined mental health service utilization, and nine reported mental health outcomes. Seventy percent of the studies recruited samples from the health systems. The rest were from community settings. Seventy percent included the Asian American subgroup, mainly Chinese Americans. Higher education, English proficiency, more years residing in the U.S., and having social support correlated with better psychological quality of life. Higher-income and education levels were associated with more psychotropic medication use. However, zip code levels were used to estimate actual income and education.

Conclusion: We identified significant SDOH factors that influenced mental health outcomes among Asian American cancer survivors. More research is needed to understand the social determinants of mental health service utilization barriers in this population. Allocating more funding to health research tailored to Asian American cancer survivors, along with data disaggregation, standardizing socioeconomic status measures, and diversifying sampling sources, is essential to enhancing their mental health outcomes.

目的:本综述的目的是确定美国亚裔美国癌症幸存者心理健康服务利用的社会决定因素与结果之间的关系。方法:我们在PubMed, PsycINFO, CINAHL和Embase中进行了系统的文献检索,检索2000年1月至2024年5月期间的同行评议研究。根据“健康人2023”框架,将健康的社会决定因素(SDOH)划分为五个SDOH领域。我们使用证据表提取数据,并使用约翰霍普金斯循证实践评估研究质量。结果:10项非实验研究符合入选标准,质量为“高”或“好”。其中两项调查了心理健康服务的利用情况,九项报告了心理健康结果。70%的研究从卫生系统中收集样本。其余的来自社区环境。70%包括亚裔美国人,主要是华裔美国人。高等教育程度、英语熟练程度、在美国居住时间更长以及拥有社会支持与更好的心理生活质量相关。较高的收入和教育水平与更多的精神药物使用有关。然而,邮政编码水平被用来估计实际收入和教育程度。结论:我们确定了影响亚裔美国癌症幸存者心理健康结果的显著SDOH因素。需要更多的研究来了解这一人群中心理健康服务利用障碍的社会决定因素。为针对亚裔美国癌症幸存者的健康研究分配更多资金,同时进行数据分类,标准化社会经济地位测量,并使抽样来源多样化,对于提高他们的心理健康结果至关重要。
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引用次数: 0
Racial Trauma and Black Mothers' Mental Health: Does Cognitive Flexibility Buffer the Effects of Racialized Stress? 种族创伤与黑人母亲的心理健康:认知灵活性是否缓冲种族化压力的影响?
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-03 DOI: 10.1007/s40615-024-02278-5
Gabriela S Revi, Lori A Francis

Racialized stress disproportionately impacts Black individuals and confers increased risk for psychological distress and executive dysfunction. However, there is little evidence on psychological distress' association with cognitive flexibility (CF), an executive function theorized to be a neurocognitive resilience factor, as it is shown to reflect the ability to adapt thoughts/behaviors to changing environmental stimuli. As such, we aimed to examine the relation between racialized stress and psychological distress and the potential buffering effects of CF. Data were drawn from The Family Life Project and included 372 Black mothers from rural households experiencing poverty. Mothers completed a battery of questionnaires to assess sociodemographics, experiences with racialized stress (RRSE), psychological distress (CES-D), and their cognitive flexibility (WCST-64). Results evidenced a significant association between psychological distress and racialized stress, such that mothers who reported higher racialized stress reported higher psychological distress; this relation remained significant after controlling for a host of sociodemographic risk factors. CF did not emerge as a significant moderator of the relation between psychological distress and racialized stress. Findings highlight the potential deleterious effects of racialized stress on psychological distress. There may be unique facets of racialized stress that differentially impact the risk for psychological distress, and CF potentially buffers this relation. Further investigations are needed to understand the underlying mechanisms that may confer resilience to psychological distress amongst Black mothers.

种族压力对黑人的影响尤为严重,并增加了心理困扰和执行功能障碍的风险。然而,心理压力与认知灵活性(CF)之间的关系却鲜有证据可循,而认知灵活性是一种被认为是神经认知复原力因素的执行功能,因为它被证明反映了根据不断变化的环境刺激调整思想/行为的能力。因此,我们旨在研究种族化压力和心理困扰之间的关系以及 CF 的潜在缓冲作用。数据来自家庭生活项目,包括 372 位来自农村贫困家庭的黑人母亲。母亲们填写了一系列问卷,以评估社会人口统计学、种族化压力体验(RRSE)、心理压力(CES-D)和认知灵活性(WCST-64)。结果表明,心理困扰与种族化压力之间存在显著关联,即报告种族化压力较高的母亲报告的心理困扰也较高;在控制了一系列社会人口风险因素后,这种关系仍然显著。在心理压力与种族化压力之间的关系中,CF 并未成为一个重要的调节因素。研究结果凸显了种族化压力对心理困扰的潜在有害影响。种族化压力可能有其独特的方面,对心理困扰的风险产生不同的影响,而 CF 有可能缓冲这种关系。还需要进一步调查,以了解可能赋予黑人母亲对心理困扰的复原力的潜在机制。
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引用次数: 0
The Interaction of Racial-Ethnic and Economic Concentration and its Association with Premature Mortality in U.S. Neighborhoods. 种族-民族和经济集中的相互作用及其与美国社区过早死亡率的关系。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-03 DOI: 10.1007/s40615-024-02251-2
Iván Mejía-Guevara, Mark R Cullen, Shripad Tuljapurkar, Vyjeyanthi S Periyakoil, David H Rehkopf

Recent research shows a significant link between race-ethnicity and income concentration and premature death rates in the U.S. However, most studies focus on Black-White residential concentration, overlooking racial-ethnic diversity. Our study examines the impact of racial-ethnic majority composition on mortality and how this relationship varies across different levels of economic concentration in neighborhoods, as defined by census tracts. Premature death rates (under 65 years of age) were retrieved from abridged period life tables from 67,140 U.S. census tracts derived from the U.S. Small-area Life Expectancy Project. Covariate factors were retrieved from the 2011-2015 American Community Survey (ACS) 5-year estimates. We measured racial-ethnic concentration by grouping neighborhoods using each tract's majority racial-ethnic group, and approximated income concentration using the Index of Concentration of the Extremes. We used three-level random intercept models to examine the interaction of racial-ethnic and income concentration and its association with neighborhood mortality risk, accounting for covariates. Our study yielded three salient findings. First, mortality risk varied greatly in poor neighborhoods with different racial-ethnic compositions compared to affluent neighborhoods, with notable higher risk in Black-majority areas. Second, in diverse neighborhoods where no single ethnic group forms a majority-referred to as Minority-majority neighborhoods-the mortality risk is comparable to that in White-majority neighborhoods. Third, Hispanic/Latino- and Asian-majority neighborhoods had lower mortality risk than White-majority neighborhoods in areas with a high concentration of poverty, but similar mortality risk in affluent areas. The study suggests that racial-ethnic and socioeconomic area-based measures are important to consider together to address mortality inequities accurately.

最近的研究表明,在美国,种族和收入集中度以及过早死亡率之间存在着显著的联系。然而,大多数研究都集中在黑人和白人居住的集中度上,而忽视了种族和民族的多样性。我们的研究考察了种族-民族多数构成对死亡率的影响,以及这种关系如何在人口普查区定义的社区中不同的经济集中度水平上发生变化。过早死亡率(65岁以下)从美国小区域预期寿命项目的67,140个美国人口普查区的精简周期生命表中检索。协变量因子从2011-2015年美国社区调查(ACS) 5年估计中检索。我们通过使用每个地区的多数种族群体对社区进行分组来测量种族集中度,并使用极端集中度指数来估算收入集中度。我们使用三水平随机截距模型来检验种族-民族和收入集中的相互作用及其与社区死亡风险的关联,并考虑协变量。我们的研究有三个显著的发现。首先,与富裕社区相比,不同种族组成的贫困社区的死亡风险差异很大,黑人占多数的地区的风险明显更高。其次,在没有单一种族群体占多数的多元化社区(即少数族裔占多数的社区),死亡风险与白人占多数的社区相当。第三,在贫困人口高度集中的地区,西班牙裔/拉丁裔和亚裔占多数的社区的死亡率风险低于白人占多数的社区,但在富裕地区的死亡率风险相似。该研究表明,基于种族-民族和社会经济区域的措施对于准确解决死亡率不平等问题非常重要。
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引用次数: 0
Health Inequalities Between Afro-descendants and Non-Afro-descendants in Peru: Evidence from the Demographic and Family Health Survey. 秘鲁非洲裔和非非洲裔之间的健康不平等:来自人口和家庭健康调查的证据。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-01-03 DOI: 10.1007/s40615-024-02265-w
Akram Hernández-Vásquez, Rodrigo Vargas-Fernández

Background: The Afro-Peruvian population is one of the ethnic minorities most affected by cultural, socioeconomic, and health barriers; however, there is little evidence on health inequalities in this ethnic group. Therefore, We aimed to determine health inequalities among the Peruvian Afro-descendant population in comparison with non-Afro-descendants.

Methods: A cross-sectional study was conducted using data from the Demographic and Family Health Survey 2022. Twenty indicators related to the health, nutrition, and well-being of the Peruvian Afro-descendant population were included. Individuals identifying as native, as well as those who did not know or did not respond to the ethnicity question, were excluded from the analysis. To assess inequalities in these indicators, the difference in percentages between Afro-descendants and non-Afro-descendants was calculated, and the percentages of these indicators across the tertiles of wealth index and the slope index of inequality (SII) were analysed for each ethnic group.

Results: Of a total of 16,875 adults and 23,206 women included in the study, 16.9% and 17.3% were of African descent, respectively. Afro-descendant population had a lower proportion of self-reported diabetes (- 1.5 percetange points (pp); 95% confidence interval (CI), - 2.7 to - 0.3); alcohol consumption in the last 30 days (- 4.5 pp; 95% CI, - 7.2 to - 1.8); higher education (- 20.6 pp, 95% CI, - 23.2 to - 18.0); access to improved water (- 3.4 pp; 95% CI, - 4.6 to - 2.1) and sanitation (- 12.1 pp; 95% CI, - 14.2 to - 10.0); cesarean section (- 9.5 pp; 95% CI, - 12.6 to - 6.4); institutional delivery (- 6.3 pp; 95% CI, - 8.4 to - 4.1); early initiation of prenatal care (- 3.3 pp; 95% CI, - 5.8 to - 0.9); birth registration (- 1.8 pp; 95% CI, - 3.4 to - 0.2) and higher proportion of stunting (+ 4.8 pp; 95% CI, 3.0 to 6.6) and adolescent maternity (+ 5.0 pp; 95% CI, 1.4 to 8.6) compared to their non-Afro-descendant counterparts. In addition, a similar wealth gap between Afro-descendant and non-Afro-descendant populations was observed in various indicators.

Conclusions: In Peru, some indicators reflect the worse living conditions faced by the Afro-descendant population compared to their non-Afro-descendant counterparts in terms of health, nutrition, and well-being.

背景:非裔秘鲁人是受文化、社会经济和健康障碍影响最大的少数民族之一;然而,几乎没有证据表明这一族群的健康不平等。因此,我们的目的是确定秘鲁非洲裔人口与非非洲裔人口之间的健康不平等。方法:采用2022年人口与家庭健康调查数据进行横断面研究。其中包括与秘鲁非洲裔人口的健康、营养和福祉有关的20项指标。被认定为本地人的个人,以及那些不知道或没有回答种族问题的人,都被排除在分析之外。为了评估这些指标的不平等,计算了非洲裔和非非洲裔之间的百分比差异,并分析了这些指标在每个种族群体的财富指数和不平等斜率指数(SII)中所占的百分比。结果:在研究中包括的16,875名成年人和23,206名女性中,非洲裔分别为16.9%和17.3%。非洲裔人群自我报告糖尿病的比例较低(- 1.5个百分点);95%置信区间(CI), - 2.7 ~ - 0.3);过去30天内的饮酒量(- 4.5 pp;95% CI, - 7.2至- 1.8);高等教育(- 20.6页,95% CI, 23.2 - 18.0);获得改善的水(- 3.4 pp;95%可信区间,4.6 - 2.1)和卫生设施(- 12.1页;95% CI, - 14.2至- 10.0);剖宫产(- 9.5 pp;95% CI, - 12.6至- 6.4);机构交付(- 6.3 pp;95% CI, - 8.4 ~ - 4.1);早期开始产前护理(- 3.3 pp;95% CI, - 5.8至- 0.9);出生登记(- 1.8页;95% CI, - 3.4至- 0.2)和更高的发育迟缓比例(+ 4.8 pp;95% CI, 3.0 - 6.6)和少女生育(+ 5.0 pp;95% CI, 1.4 - 8.6),与非非洲人后裔相比。此外,在各种指标中也观察到非洲人后裔和非非洲人后裔之间存在类似的财富差距。结论:在秘鲁,一些指标反映出非洲裔人口在健康、营养和福祉方面面临的生活条件比非非洲裔人口更差。
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引用次数: 0
Correction: Prevalence and Associated Risk Factors of Hypertension Among Tribal Population Aged 15-49 in India: Evidence from National Family Health Survey, 2019-2021. 修正:印度15-49岁部落人口高血压患病率及相关危险因素:来自2019-2021年全国家庭健康调查的证据。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-31 DOI: 10.1007/s40615-024-02279-4
Saravanan Chinnaiyan, Aravind Dharmaraj, Bharathi Palanisamy
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引用次数: 0
Maternity Care Experiences of African-Born Women Living in Melbourne, Australia: A Qualitative Descriptive Study. 生活在澳大利亚墨尔本的非洲裔妇女的产科护理经验:一项定性描述性研究。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-30 DOI: 10.1007/s40615-024-02264-x
Ayele Geleto Bali, Vidanka Vasilevski, Linda Sweet

Background: African-born women in Australia are more likely to experience poorer perinatal outcomes than their Australian-born counterparts. This disparity may be attributed to difficulties in accessing maternity care services. With a rapidly growing African-born population in Australia, understanding African-born women's experiences with maternity care is crucial for ensuring equitable access.

Aim: This study aimed to explore the access to and experiences of maternity care among African-born women living in Melbourne, Australia.

Methods: A qualitative descriptive study was conducted from September to December 2023, involving 15 purposively selected African-born women. An apriori analytic approach was applied to present the findings using the World Health Organization's Availability, Accessibility, Acceptability, and Quality framework. Data management and analysis were undertaken using NVivo 14.

Results: Participants from nine different African countries shared their experiences regarding their most recent encounters with maternity care in Australia. Key challenges identified included difficulties navigating the healthcare system, lack of social support, discomfort with male clinicians, experiences of discrimination, inadequate information, transportation issues, perceived lack of empowerment, financial constraints, and clinician cultural insensitivity. These factors negatively impacted their maternity care experiences.

Conclusions: This study provides empirical evidence to inform policies, practices, and strategies aimed at improving maternity care experiences for African-born women in Australia. There is a need for clinicians to be more aware of and sensitive to these women's cultural needs. Developing and implementing a culturally responsive service model could mitigate negative experiences and enhance access to adequate maternity care, ultimately improving perinatal health outcomes for these women.

背景:在澳大利亚出生的非洲妇女比在澳大利亚出生的妇女更有可能经历更差的围产期结果。这种差异可能是由于难以获得产妇保健服务造成的。随着澳大利亚非洲裔人口的迅速增长,了解非洲裔妇女在产科护理方面的经验对于确保公平获得至关重要。目的:本研究旨在探讨生活在澳大利亚墨尔本的非洲裔妇女获得产科护理的机会和经验。方法:于2023年9月至12月进行定性描述性研究,有目的地选择15名非洲出生的女性。使用世界卫生组织的可得性、可及性、可接受性和质量框架,采用先验分析方法来呈现研究结果。使用NVivo 14进行数据管理和分析。结果:来自九个不同非洲国家的参与者分享了他们最近在澳大利亚遇到的产妇护理经验。确定的主要挑战包括在医疗保健系统中导航困难,缺乏社会支持,与男性临床医生的不适,歧视经历,信息不足,交通问题,感知到缺乏授权,财务限制以及临床医生对文化的不敏感。这些因素对她们的产科护理经历产生了负面影响。结论:本研究为政策、实践和策略提供了经验证据,旨在改善澳大利亚非洲裔妇女的产科护理经验。临床医生有必要对这些妇女的文化需求更加了解和敏感。制定和实施符合文化的服务模式可以减轻负面经历,增加获得适当产妇护理的机会,最终改善这些妇女的围产期健康结果。
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引用次数: 0
Racial and Ethnic Differences in Long-Term Outcomes among Individuals with Opioid Use Disorder at Opioid Treatment Programs. 阿片类药物治疗项目中阿片类药物使用障碍患者长期结局的种族和民族差异
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-28 DOI: 10.1007/s40615-024-02273-w
Yuhui Zhu, Sarah J Cousins, Sarah E Clingan, Larissa J Mooney, Andrew J Saxon, Elizabeth A Evans, Yih-Ing Hser

Objectives: Racial and ethnic differences in long-term outcomes associated with medications for opioid use disorder (MOUD) are poorly understood.

Methods: The present analyses were based on 751 participants with opioid use disorder (OUD) who were initially recruited from opioid treatment programs located in California, Connecticut, Oregon, Pennsylvania, and Washington and participated in a randomized controlled trial and at least one follow-up interview. 9.6% (n = 72) of the participants self-identified as Non-Hispanic (NH) Black, 16.0% (n = 120) Hispanic, and 74.4% (n = 559) NH White. We tested racial and ethnic differences in psychiatric or social functioning, substance use and treatment participation.

Results: From the baseline to the end of follow-up interview, compared with NH White, Hispanic participants had a significantly greater proportion of months reporting any opioid use (45.5% vs. 32.5%, p < 0.001) and a smaller proportion of months receiving any MOUD (47.7% vs. 58.1%; p < 0.05), particularly receipt of buprenorphine treatment (8.3% vs. 14.9%; p < 0.01). At the third follow-up interview, data from the Addiction Severity Index (ASI) indicated that Hispanic participants had greater severity in employment problems (0.72 vs. 0.58; p < 0.001), while Black participants had less severity in drug problems (0.11 vs. 0.16; p < 0.05) compared to NH Whites.

Conclusions: The study found that Hispanic participants had higher rates of opioid use (heroin and prescription opioids), but few received MOUD (buprenorphine and methadone) during the follow-up period, which suggests that effective strategies are needed to increase access to MOUD among Hispanics. Additionally, addressing employment challenges might also help improve long-term outcomes for all populations with OUD.

目的:与阿片类药物使用障碍(mod)相关的长期结局的种族和民族差异尚不清楚。方法:目前的分析基于751名阿片类药物使用障碍(OUD)的参与者,他们最初从位于加利福尼亚州,康涅狄格州,俄勒冈州,宾夕法尼亚州和华盛顿州的阿片类药物治疗项目中招募,并参加了一项随机对照试验和至少一次随访访谈。9.6% (n = 72)的参与者自认为是非西班牙裔(NH)黑人,16.0% (n = 120)西班牙裔,74.4% (n = 559) NH白人。我们测试了种族和民族在精神或社会功能、物质使用和治疗参与方面的差异。结果:从基线到随访结束,与NH White相比,西班牙裔参与者报告阿片类药物使用的月份比例明显更高(45.5%对32.5%,p)。研究发现,西班牙裔参与者使用阿片类药物(海洛因和处方阿片类药物)的比例较高,但在随访期间很少有人接受mod(丁丙诺啡和美沙酮),这表明需要有效的策略来增加西班牙裔参与者获得mod的机会。此外,解决就业挑战也可能有助于改善所有OUD患者的长期结果。
{"title":"Racial and Ethnic Differences in Long-Term Outcomes among Individuals with Opioid Use Disorder at Opioid Treatment Programs.","authors":"Yuhui Zhu, Sarah J Cousins, Sarah E Clingan, Larissa J Mooney, Andrew J Saxon, Elizabeth A Evans, Yih-Ing Hser","doi":"10.1007/s40615-024-02273-w","DOIUrl":"https://doi.org/10.1007/s40615-024-02273-w","url":null,"abstract":"<p><strong>Objectives: </strong>Racial and ethnic differences in long-term outcomes associated with medications for opioid use disorder (MOUD) are poorly understood.</p><p><strong>Methods: </strong>The present analyses were based on 751 participants with opioid use disorder (OUD) who were initially recruited from opioid treatment programs located in California, Connecticut, Oregon, Pennsylvania, and Washington and participated in a randomized controlled trial and at least one follow-up interview. 9.6% (n = 72) of the participants self-identified as Non-Hispanic (NH) Black, 16.0% (n = 120) Hispanic, and 74.4% (n = 559) NH White. We tested racial and ethnic differences in psychiatric or social functioning, substance use and treatment participation.</p><p><strong>Results: </strong>From the baseline to the end of follow-up interview, compared with NH White, Hispanic participants had a significantly greater proportion of months reporting any opioid use (45.5% vs. 32.5%, p < 0.001) and a smaller proportion of months receiving any MOUD (47.7% vs. 58.1%; p < 0.05), particularly receipt of buprenorphine treatment (8.3% vs. 14.9%; p < 0.01). At the third follow-up interview, data from the Addiction Severity Index (ASI) indicated that Hispanic participants had greater severity in employment problems (0.72 vs. 0.58; p < 0.001), while Black participants had less severity in drug problems (0.11 vs. 0.16; p < 0.05) compared to NH Whites.</p><p><strong>Conclusions: </strong>The study found that Hispanic participants had higher rates of opioid use (heroin and prescription opioids), but few received MOUD (buprenorphine and methadone) during the follow-up period, which suggests that effective strategies are needed to increase access to MOUD among Hispanics. Additionally, addressing employment challenges might also help improve long-term outcomes for all populations with OUD.</p>","PeriodicalId":16921,"journal":{"name":"Journal of Racial and Ethnic Health Disparities","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developing a Charlson Comorbidity Index for the American Indian Population Using the Epidemiologic Data from the Strong Heart Study. 利用强心脏研究的流行病学数据为美洲印第安人建立查尔森合并症指数。
IF 3.2 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-27 DOI: 10.1007/s40615-024-02261-0
Paul Rogers, Christine Merenda, Richardae Araojo, Christine Lee, Milena Lolic, Ying Zhang, Jessica Reese, Kimberly Malloy, Dong Wang, Wen Zou, Joshua Xu, Elisa Lee

Background: The Charlson Comorbidity Index (CCI) is a frequently used mortality predictor based on a scoring system for the number and type of patient comorbidities health researchers have used since the late 1980s. The initial purpose of the CCI was to classify comorbid conditions, which could alter the risk of patient mortality within a 1-year time frame. However, the CCI may not accurately reflect risk among American Indians because they are a small proportion of the US population and possibly lack representation in the original patient cohort. A motivating factor in calibrating a CCI for American Indians is that this population, as a whole, experiences a greater burden of comorbidities, including diabetes mellitus, obesity, cancer, cardiovascular disease, and other chronic health conditions, than the rest of the US population.

Methods: This study attempted to modify the CCI to be specific to the American Indian population utilizing the data from the still ongoing The Strong Heart Study (SHS) - a multi-center population-based longitudinal study of cardiovascular disease among American Indians. A 1-year survival analysis with mortality as the outcome was performed using the SHS morbidity and mortality surveillance data and assessing the impact of comorbidities in terms of hazard ratios with the training cohort. A Kaplan-Meier plot for a subset of the testing cohort was used to compare groups with selected mCCI-AI scores.

Results: A total of 3038 Phase VI participants from the SHS comprised the study population for whom mortality and morbidity surveillance data were available through December 2019. The weights generated by the SHS participants for myocardial infarction, congestive heart failure, and high blood pressure were greater than Charlson's original weights. In addition, the weights for liver illness were equivalent to Charlson's severe form of the disease. Lung cancer had the greatest overall weight derived from a hazard ratio of 8.31.

Conclusions: The mCCI-AI was a statistically significant predictor of 1-year mortality, classifying patients into different risk strata χ2 (8, N = 1,245) = 30.56 (p = 0.0002). The mCCI-AI was able to discriminate between participants who died and those who survived 73% of the time.

背景:Charlson共病指数(CCI)是一种常用的死亡率预测指标,该指标基于一种评分系统,用于评估患者共病的数量和类型,自20世纪80年代末以来,卫生研究人员一直在使用该评分系统。CCI的最初目的是对合并症进行分类,这些合并症可能会在1年内改变患者死亡的风险。然而,CCI可能不能准确反映美洲印第安人的风险,因为他们只占美国人口的一小部分,可能在原始患者队列中缺乏代表性。校准美洲印第安人CCI的一个激励因素是,与美国其他人口相比,这一人口总体上承受着更大的合并症负担,包括糖尿病、肥胖、癌症、心血管疾病和其他慢性健康状况。方法:本研究利用仍在进行的强心脏研究(SHS)的数据,试图修改CCI,使其适用于美洲印第安人,这是一项针对美洲印第安人心血管疾病的多中心人群纵向研究。使用SHS发病率和死亡率监测数据进行以死亡率为结果的1年生存分析,并根据培训队列的风险比评估合并症的影响。测试队列子集的Kaplan-Meier图用于比较具有选定mCCI-AI分数的组。结果:截至2019年12月,共有3038名来自SHS的VI期参与者组成了研究人群,他们的死亡率和发病率监测数据可用。SHS参与者在心肌梗死、充血性心力衰竭和高血压方面产生的体重大于Charlson的原始体重。此外,肝脏疾病的体重与查尔森的严重形式的疾病相当。肺癌的总重量最大,风险比为8.31。结论:mCCI-AI是1年死亡率的显著预测因子,可将患者分为不同的危险层,χ2 (8, N = 1,245) = 30.56 (p = 0.0002)。mCCI-AI在73%的情况下能够区分死亡和存活的参与者。
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引用次数: 0
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Journal of Racial and Ethnic Health Disparities
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