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Co-Morbidly of Malaria and Typhoid Perturbs Lipid Homeostasis in Humans 疟疾和伤寒共病扰乱人体内脂质稳态
Pub Date : 2021-12-18 DOI: 10.36108/jrrslasu/1202.80.0101
A. Akamo
Introduction: Malaria and typhoid diseases have remained endemic in low-income countries, including Nigeria. Aims: This study investigated the impact of malaria concurrently occurring with typhoid on plasma, erythrocytes, and lipoproteins lipid profile. Materials and Methods: Cholesterol, triacylglycerol (TAG) phospholipids (PLs), and non-esterified fatty acids (NEFAs) were determined spectrophotometrically in controls and patients presenting at the Out-Patient Clinic of the State Hospital, Abeokuta, Nigeria. Results: The presence of either or both parasitic infections provoked dyslipidaemia when compared with the controls. Dyslipidaemia was characterised by significant (P < 0.05) decreased plasma, erythrocytes, high density lipoprotein (HDL), and low density lipoprotein (LDL) cholesterol; however very LDL (VLDL) cholesterol increased. While hypertriglyceridemia was observed in plasma, hypotriglyceridemia was observed in the erythrocytes of the patients. In HDL, hypertriglyceridemia was observed in malaria-infected patients whereas hypotriglyceridemia was observed in typhoid-infected and co-infection subjects. Malaria and/or typhoid induced phospholipidaemia in plasma and erythrocytes, but provoked decreased HDL-phospholipids (PLs) only in malaria-infected patients. Malaria and/or typhoid elicited decreased LDL+VLDL-PLs. While increased plasma NEFAs concentration was observed in malaria-infected patients; malaria and co-infection resulted in decreased erythrocytes NEFAs. Malaria and/or typhoid caused decreased cholesterol/phospholipids molar ratio in plasma, erythrocytes, and HDL. Conclusion: The findings of this study indicate that parasitic protozoa and bacterial infections produce a plethora of effects on lipid metabolism, ranging from up-/down-regulation of certain lipid metabolites. These may be early biochemical events in the induction of atherosclerosis by parasitic infections.
导言:疟疾和伤寒在包括尼日利亚在内的低收入国家仍然是地方病。目的:本研究探讨疟疾并发伤寒对血浆、红细胞和脂蛋白脂质谱的影响。材料和方法:用分光光度法测定了在尼日利亚阿贝奥库塔国家医院门诊就诊的对照和患者的胆固醇、三酰甘油(TAG)磷脂(PLs)和非酯化脂肪酸(NEFAs)。结果:与对照组相比,存在一种或两种寄生虫感染引起血脂异常。血脂异常以血浆、红细胞、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)胆固醇显著降低(P < 0.05)为特征;但低密度脂蛋白(VLDL)胆固醇升高。血浆中有高甘油三酯血症,红细胞中有低甘油三酯血症。在HDL中,疟疾感染患者出现高甘油三酯血症,而伤寒感染和合并感染患者出现低甘油三酯血症。疟疾和/或伤寒引起血浆和红细胞中的磷脂血症,但仅在疟疾感染患者中引起hdl -磷脂(PLs)下降。疟疾和/或伤寒引起LDL+VLDL-PLs降低。疟疾感染患者血浆NEFAs浓度升高;疟疾和合并感染导致红细胞NEFAs减少。疟疾和/或伤寒引起血浆、红细胞和高密度脂蛋白胆固醇/磷脂摩尔比降低。结论:本研究结果表明,寄生原生动物和细菌感染对脂质代谢产生多种影响,包括上调/下调某些脂质代谢产物。这些可能是寄生虫感染诱导动脉粥样硬化的早期生化事件。
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引用次数: 0
Natural Radionuclide Concentrations and Associated Doses Around Three Dumpsites in Lagos, Nigeria 尼日利亚拉各斯三个垃圾场周围的天然放射性核素浓度和相关剂量
Pub Date : 2021-11-14 DOI: 10.36108/jrrslasu/1202.80.0190
A. Ogunremi, Adeola Olaoye Morounfolu
Monitoring of environmental radiation helps to ascertain healthy vicinity which is a catalyst to the economic development of the area. Activity concentration of naturally occurring radionuclides in three (3) dumpsites in Lagos State, Olusosun Landfill, Ojota, Ilupeju dumpsite and, Gbagada dumpsite Lagos state, Nigeria were investigated using gamma-ray spectroscopy to obtain the level of radioactive exposure hazards experienced by people living in these vicinities. A total of thirty soil samples were randomly collected into a polythene bag. They were oven-dried at 110°C, pulverized, and sieved. Quantities of the samples (400 g) were sealed in cylindrical sample holders and kept for about 28 days to attain secular equilibrium between 226Ra and its decay products before analysis using gamma-ray spectrometry. The mean activity concentration obtained for 40K, 238U, and 234Th at, Ilupeju, Gbagada, and Ojota were 339.23±33.66, 11.83±19.174, 11.95±22.752 Bq/kg, 337.56 ± 36.22, 11.49±22.14, 11.54 ± 19.33 Bq/kg and 334.87±32.44, 11.42±22.39, 11.56±18.52 Bq/kg respectively. The mean absorbed dose nGy/h, annual effective dose mSv/y were calculated and their results were found to be below the global values. The results indicate that the radiation level within the dumpsites poses no significant health risk to the people living close to the dumpsites.
环境辐射监测有助于确定健康的邻近地区,这是该地区经济发展的催化剂。利用伽马射线能谱法调查了尼日利亚拉各斯州Olusosun垃圾填埋场、Ojota、Ilupeju垃圾填埋场和Lagos州Gbagada垃圾填埋场三(3)处天然存在的放射性核素的活动浓度,以获得居住在这些地区的人们所经历的放射性暴露危害水平。随机抽取30份土壤样本装入塑料袋。它们在110°C下烘干,粉碎并过筛。将大量样品(400 g)密封在圆柱形样品容器中,保存约28天,以达到226Ra及其衰变产物之间的长期平衡,然后使用伽马射线能谱法进行分析。40K、238U、234的平均活性浓度分别为339.23±33.66、11.83±19.174、11.95±22.752 Bq/kg、337.56±36.22、11.49±22.14、11.54±19.33 Bq/kg和334.87±32.44、11.42±22.39、11.56±18.52 Bq/kg。计算了平均吸收剂量nGy/h和年有效剂量mSv/y,发现其结果低于全球值。结果表明,堆积场内的辐射水平对堆积场附近居民不构成显著的健康风险。
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引用次数: 1
Climatic Bases and Analysis of Proposed Cloud Attenuation Model for Satellite Links Application 用于卫星链路应用的云衰减模型的气候基础和分析
Pub Date : 2021-10-01 DOI: 10.36108/jrrslasu/1202.80.0180
M. O. Adewusi
Consistently required lager bandwidth at lower cost induce increases in magnitude of transmission frequency for satellite signal. This is phenomenally accompanied by proportional hydrometeors attenuation. Hence, there is need to evaluate cloud attenuation impact in every climatic region periodically. This report is one of the outcomes of experimental communication research carried out at tropical Ota (6.7oN, 3.23oE) station, southwest, Nigeria. The station spectrum analyzer measures its received beacons total attenuation at 12.245 GHz and elevation angle 59.9o to Astra satellites located at 28.2oE. Daily maximum, minimum and mean temperatures; rain amount, wind speed and direction as well as time of occurrence of each of these weather parameters were also measured. Then the radiometric data including acquired radiosonde data were analysed under rainy and non-rainy conditions, to obtain cloud attenuation contribution from the total attenuation measured per minute. The various data used range in measurement periods between four and fifty-eight years. The outputs were used to compute the station cumulative distributions for the existing cloud models and for the integrated station’s data. Statistical analysis comparing the two cumulative distributions show a high difference between the measured data and existing models’ predicted values. Hence a cloud attenuation computation algorithm and its simulation program were developed and used to derive a new tropical cloud attenuation model. The results of climatic data and analysis were used to justify the well corroborated new cloud attenuation model.
不断要求以较低的成本获得更大的带宽,导致卫星信号传输频率的增加。这明显伴随着成比例的水成物衰减。因此,有必要定期评估各气候区的云衰减影响。本报告是在尼日利亚西南部热带Ota (6.7oN, 3.23oE)站进行的实验性通信研究成果之一。台站频谱分析仪测量其接收信标的总衰减在12.245 GHz和仰角59.90到位于28.20东经的Astra卫星。日最高、最低和平均气温;雨量、风速和风向以及这些天气参数的发生时间也被测量。然后分析了降雨和非降雨条件下的辐射数据,包括探空数据,从每分钟测量的总衰减中获得云衰减的贡献。所使用的各种数据的测量周期从4年到58年不等。输出用于计算现有云模式和综合站数据的站点累积分布。对两种累积分布的统计分析表明,实测数据与现有模型的预测值之间存在较大差异。为此,开发了一种云衰减计算算法及其模拟程序,并利用该算法推导了一种新的热带云衰减模型。气候资料和分析的结果被用来证明新的云衰减模型得到了很好的证实。
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引用次数: 0
Heavy Metals Concentration In Underground Water And Its Environmental Health Effects: A Case Study Of Solous Dumpsite, Igando, Lagos 地下水重金属浓度及其对环境健康的影响——以拉各斯Igando索洛斯垃圾场为例
Pub Date : 2021-10-01 DOI: 10.36108/jrrslasu/1202.80.0170
Joshua Olu
Introduction: Contaminated water is linked to diseases worldwide. Aims: To investigate the heavy metals concentration in underground water around the Solous dumpsite in Igando Lagos State, Nigeria and its effect on human. Materials and Methods: water samples from 12 different locations within a distance range of 0.07 - 0.72 km was collected. And a structured questionnaire was administered to 120 respondents to find out their perceptions about the dumpsite environment and ill-health effect of their drinking water. The physicochemical parameters was measured and heavy metals concentration of the water samples were determined using Flame Atomic Absorption Spectrometer. Results: The water samples from the 12 sites contains heavy metals concentrations: Lead (Pb) (0.08-1.20mg/L), Cadmium (Cd) (0.03-0.08mg/L), Iron (Fe) (1.4-12.3mg/L), Nickel (Ni) (0.08-0.19mg/L), Zinc (Zn) (0.05-0.13mg/L) and Manganese (Mn) (0.01-0.04mg/L) respectively. It was revealed that age, educational qualification and year of living in the community of the respondents explain a significant amount of the variance in the value of the perception of the respondents on effect of heavy metal contamination. The result shows that over 75% of the respondents was not sure of any prior ailment linked to any heavy metal contamination affecting anyone among them. Conclusion: all water samples collected were contaminated by heavy metals and respondents using this water are ignorant of the danger. Thus, there is a need for proper provision of safe alternative water supply to the dumpsite community for domestic use and awareness on environmental heavy metal toxicity from drinking water to avert global health challenges.
在世界范围内,受污染的水与疾病有关。目的:了解尼日利亚伊干多拉各斯州索洛斯垃圾场周边地下水重金属含量及其对人体的影响。材料与方法:在0.07 ~ 0.72 km范围内的12个不同地点采集水样。并对120名受访者进行了结构化问卷调查,以了解他们对垃圾场环境和饮用水对健康的不良影响的看法。用火焰原子吸收光谱仪测定了水样的理化参数和重金属浓度。结果:12个站点的水样中重金属含量分别为铅(Pb) (0.08 ~ 1.20mg/L)、镉(Cd) (0.03 ~ 0.08mg/L)、铁(Fe) (1.4 ~ 12.3mg/L)、镍(Ni) (0.08 ~ 0.19mg/L)、锌(Zn) (0.05 ~ 0.13mg/L)和锰(Mn) (0.01 ~ 0.04mg/L)。调查显示,受访者的年龄、教育程度和在社区生活的年份解释了受访者对重金属污染影响的感知价值的显著差异。调查结果显示,超过75%的受访者不确定自己是否曾患过与重金属污染有关的疾病。结论:所有采集的水样都被重金属污染,而使用该水的受访者对其危险一无所知。因此,有必要向垃圾场社区适当提供安全的替代供水供家庭使用,并提高对饮用水重金属环境毒性的认识,以避免全球健康挑战。
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引用次数: 0
Antioxidant and Esterases Profiling of diabetes-induced rat and tissues compartmentalisation. 糖尿病大鼠抗氧化和酯酶谱及组织区隔化。
Pub Date : 2021-10-01 DOI: 10.36108/jrrslasu/1202.80.0160
A. Wusu
Enormous complications associated with diabetes contribute to the therapeutic challenge confronting most of the world, including developing countries. This study was carried out to investigate diabetes mellitus on esterases and antioxidant enzymes in different tissues compartments of rats. Animals were divided into two groups of 10 animals each. The experimental group was confirmed diabetic by a single dose of streptozotocin injection (STZ, freshly dissolved in citrate buffer, pH 4.5, 50 mg/kg) intraperitoneally. In contrast, the control group was injected with citrate buffer only. Blood glucose and weight of the animals were monitored for 7 days. Blood, liver and brain were removed, and biochemical parameters determined spectrophotometrically. Diabetes produced various degrees of alterations in antioxidant defence mechanism and esterases activities that are compartment specific. Acetylcholinesterase (AChE) activity was inhibited to various extents. While AChE was inhibited to the tune of 39% in plasma, 33% in the brain and 30% in the liver, activation of the activity was observed in the red blood cell (RBC). The same trend of significant (p < 0.001) inhibition was observed with arylesterase in the plasma, brain and liver, and activation in the RBC. Diabetes induced significant (p<0.001) inhibition in catalase, Glutathione-S-transferase, and Superoxide dismutase in the brain and liver, respectively, compared to control more than the other compartments. However, activation was also observed in the RBC of these enzymes except for catalase and nitric oxide. In conclusion, distinct compartments effects of diabetes observed in this study could suggest a new approach for effective and safer therapeutics.
与糖尿病相关的大量并发症使包括发展中国家在内的世界大多数国家面临治疗挑战。本研究探讨了糖尿病大鼠不同组织室中酯酶和抗氧化酶的变化。动物被分成两组,每组10只。实验组小鼠经单次腹腔注射链脲佐菌素(STZ,新鲜溶解于柠檬酸缓冲液中,pH 4.5, 50 mg/kg)证实为糖尿病。对照组只注射柠檬酸缓冲液。监测各组动物的血糖和体重,为期7 d。取血、肝、脑,分光光度法测定生化参数。糖尿病在抗氧化防御机制和酯酶活性方面产生不同程度的改变,这些改变是室特异性的。乙酰胆碱酯酶(AChE)活性受到不同程度的抑制。乙酰胆碱酯酶在血浆中被抑制39%,在脑中被抑制33%,在肝脏中被抑制30%,而在红细胞(RBC)中被激活。血浆、脑和肝脏中的芳基酯酶以及红细胞中的激活也有同样的显著抑制趋势(p < 0.001)。与对照组相比,糖尿病分别诱导大脑和肝脏过氧化氢酶、谷胱甘肽- s转移酶和超氧化物歧化酶的显著抑制(p<0.001)。然而,除过氧化氢酶和一氧化氮外,在红细胞中也观察到这些酶的活化。总之,在本研究中观察到的糖尿病不同的室室效应可能为有效和更安全的治疗方法提供新的途径。
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引用次数: 0
Modulation of the Complement system by Zingiberacea Aframomum Melegueta in mice-induced Schizophrenia 紫姜对小鼠精神分裂症补体系统的调节作用
Pub Date : 2021-09-01 DOI: 10.36108/jrrslasu/1202.80.0140
Thona Wusu
Introduction: Schizophrenia is a severe mental disorder among nationalities of the world, which has a substantial social and economic effect. Scientific therapeutic drugs have proved abortive due to adverse effects. Aim: The study investigated the repression of the complement system by aqueous extract of alligator pepper on schizophrenia. Methods: Male mice were induced with schizophrenia using ketamine and dexamethasone; the mice were treated with aqueous extract of alligator pepper (200mg/ml and 400mg/ml) respectively for ten days. After which their brain was removed, and analysed for dopamine. Blood samples was collected from the animal and plasma was used to determine the level of complement component (3 and 4), and C-reactive protein spectrophotometrically. Phytochemical content of the aqueous extract was also done spectrophotometrically, and characterization was confirmed using FTIR. Result: The alligator plant extract constituent includes flavonoids, tannins, saponin, steroids, phlabotannis, terpenoids, and cardiac glycoside. With a tannins having a concentration of 1292.6 µg/ml and 726.8µg/ml, phenol had a concentration of 221.7 µg/ml and 94.2 µg/ml and flavonoids had a concentration of 105.3 µg/ml and 100.0 µg/ml at 200mg/ml and 400mg/ml plant concentration respectively. The alligator pepper reversed the effect of ketamine and dexamethasone induced schizophrenia by decreasing the level of C-reactive protein , complement component (3 and 4) and dopamine significantly (<0.0001) in a dose dependent manner, in all the groups compared to the control. Conclusion: The high phenolic and flavonoids content in alligator pepper may be responsible for the antipsychotic property of alligator pepper. Thus, probable natural therapy for schizophrenia.
精神分裂症是世界各民族的一种严重精神障碍,具有重大的社会和经济影响。科学的治疗药物由于副作用被证明是无效的。目的:研究鳄椒水提物对精神分裂症补体系统的抑制作用。方法:用氯胺酮和地塞米松诱导雄性小鼠精神分裂症;分别给予鳄鱼椒水提物(200mg/ml和400mg/ml) 10 d。之后,他们的大脑被移除,并进行多巴胺分析。采集动物血样,用血浆分光光度法测定补体成分(3和4)和c反应蛋白的水平。用分光光度法测定了水提物的植物化学成分,并用FTIR进行了表征。结果:短吻鳄植物提取物成分包括黄酮类、单宁类、皂苷类、甾体类、棕藓属、萜类、心糖苷类。单宁浓度分别为1292.6µg/ml和726.8µg/ml,苯酚浓度分别为221.7µg/ml和94.2µg/ml,黄酮类化合物浓度分别为105.3µg/ml和100.0µg/ml。与对照组相比,鳄鱼辣椒通过降低c反应蛋白、补体成分(3和4)和多巴胺的水平(<0.0001),以剂量依赖的方式逆转了氯胺酮和地塞米松诱导的精神分裂症的影响。结论:鳄椒中酚类和类黄酮含量较高,可能与鳄椒具有抗精神病作用有关。因此,可能是精神分裂症的自然疗法。
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引用次数: 0
Biodegradation of Escravos light crude oil by three indigenous bacteria, isolated from mechanic workshop in Lagos State Nigeria 尼日利亚拉各斯州机械车间分离的三种本地细菌对埃斯克拉沃斯轻质原油的生物降解
Pub Date : 2021-09-01 DOI: 10.36108/jrrslasu/1202.80.0150
B. Opere
Introduction: Petroleum hydrocarbons can be degraded by microorganisms such as bacteria, fungi, yeast and microalgae. However, bacteria play an imperative role in hydrocarbon degradation. Microorganisms are endowed with metabolism machinery to use petroleum products as a carbon and energy source Aims: The aim of the study is to isolate hydrocarbon degrading bacteria from hydrocarbon polluted site (mechanic workshops) in Lagos state. Materials and Methods: The physical, chemical and microbiological properties of the three soil sample were analyzed using standard procedure. Hydrocarbon degraders were isolated on 1% crude oil mineral salt medium via enrichment technique. The best hydrocarbon degrader were identified on the basis of their colonial morphology, biochemical characteristics and complemented with analytical profile index (API) kit. Hydrocarbon degradation were monitored using total viable count and residual oil was determined by Gas Chromatography equipped with Flame Ionized detector (GC-FID). Results: Alkaline pH were observed for all three soil samples, the total nitrogen detected were 0.07, 0.04 and 0.1. The total heterotrophic bacteria (THB) estimated were 3 x 1010, 6.5 x 109 and 1.7 x 1010 cfu/ml while the total hydrocarbon utilizing bacteria estimated via vapour phase were 1.89 x 106 , 4x104 and 9.62 x 107 cfu/ml for Ikeja, Iyana-Iba and Mushin sample. The organisms had a generation time of 5.56, 9.09 and 10.9 (d), the degradation half-life were 3.85, 6.3 and 7.5 (d) respectively. Over 60% hydrocarbon degradation were determined within 10 days for all three isolates. The Gc-fid prints shows reduction in peak area of various hydrocarbon fractions with a decrease in pH of the medium. Conclusion: The study showed that hydrocarbon degraders are ubiquitously distributed in the hydrocarbon polluted soil sample. Their degradation potential can be optimized so as curtail the adverse effect of petroleum in the environment
石油碳氢化合物可被细菌、真菌、酵母和微藻等微生物降解。然而,细菌在碳氢化合物的降解中起着至关重要的作用。目的:从拉各斯州的烃污染场所(机械车间)分离出烃降解细菌。材料与方法:采用标准程序对三种土壤样品的物理、化学和微生物特性进行分析。采用富集技术在1%原油矿物盐培养基上分离出烃类降解物。根据菌落形态、生化特性,并辅以分析剖面指数(API)试剂盒,筛选出最佳的烃降解剂。采用总活菌计数法监测烃类降解情况,采用气相色谱-火焰离子化检测器(GC-FID)测定残油。结果:3种土壤样品均呈碱性,总氮含量分别为0.07、0.04和0.1。Ikeja, Iyana-Iba和Mushin样品的总异养细菌(THB)估计为3 × 1010, 6.5 × 109和1.7 × 1010 cfu/ml,而通过气相估计的总碳氢化合物利用细菌为1.89 × 106, 4x104和9.62 × 107 cfu/ml。降解半衰期分别为3.85、6.3和7.5 (d),代时间分别为5.56、9.09和10.9 (d)。在10天内,这三种分离物的碳氢化合物降解率均超过60%。Gc-fid图谱显示,随着介质pH值的降低,各烃类组分的峰面积减小。结论:研究表明烃类降解物在烃污染土壤样品中普遍存在。可以优化其降解潜力,减少石油对环境的不利影响
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引用次数: 0
FOSIC2020: Science and Technology in Combating Current and Future Global Challenges (LASU Virtual Conference, 2- 4 December 2020) FOSIC2020:科学和技术应对当前和未来的全球挑战(LASU虚拟会议,2020年12月2日至4日)
Pub Date : 2021-08-17 DOI: 10.36108/jrrslasu/1202.80.0130
A. Anjorin
The Lagos State University 7th bi-annual Faculty of Science International Conference 2020 tagged LASU FOSIC2020 was held virtually from 2nd-4th December, 2020. The theme of the conference was Science and Technology in combating current and future global challenges. To justify the theme, different sub-themes were combined cutting across biological/medical, chemical and physical sciences including: global ecology and challenges of combating infectious human and zoonotic diseases, emerging perspectives on epidemiology of infectious diseases, post COVID-19 effects on fisheries and aquaculture, molecular approaches in curtailing the scourge of diseases, chemistry of natural resources for sustainable product development, medicinal plants as antidotes, dynamical system analysis, modelling and optimization, artificial intelligence in the 4th industrial revolution, and demystifying 5G technology: the role of physics in tackling global health challenges. This summary therefore presents some of the observations raised at the conference. Topical models and practical strategies at flattening the curve of COVID-19 pandemic in African most populous city, Lagos was presented by the Deputy Governor of Lagos State, while Director General of the Nigerian Institute for Medical Research delivered the keynote address followed by the special guest speaker from Harvard Medical School and Massachusetts General hospital, USA amongst others. To the best of our knowledge, FOSIC2020 was the first free and 100% virtual international conference organised by any Nigerian University to date. Overall, a total of 130 papers were presented by researchers out of the 334 registered participants representing 36 institutions from 14 countries across the world. FOSIC2020 was declared closed with a free technical workshop focusing on V2V global partnership from vulnerability to viability project by the team leaders from the University of Waterloo Canada and Lagos State University with members of panel as postgraduate students across different countries. Free electronics book of abstracts and certificates were given to all the participants.
拉各斯州立大学第七届两年一次的科学学院国际会议2020,标签为LASU FOSIC2020,于2020年12月2日至4日举行。会议的主题是“科学和技术在应对当前和未来全球挑战中的作用”。为证明这一主题的合理性,将生物/医学、化学和物理科学领域的不同分主题结合起来,包括:全球生态学和应对传染性人类和人畜共患疾病的挑战、传染病流行病学的新观点、COVID-19后对渔业和水产养殖的影响、减少疾病祸害的分子方法、用于可持续产品开发的自然资源化学、作为解毒剂的药用植物、动力系统分析、建模和优化、第四次工业革命中的人工智能、揭开5G技术的神秘面纱:物理学在应对全球健康挑战中的作用。因此,本摘要提出了会议上提出的一些意见。拉各斯州副州长介绍了在非洲人口最多的城市拉各斯扁平化COVID-19大流行曲线的专题模型和实用策略,尼日利亚医学研究所总干事发表了主题演讲,随后是来自哈佛医学院和美国马萨诸塞州总医院等的特别演讲嘉宾。据我们所知,FOSIC2020是迄今为止由尼日利亚大学组织的第一个免费和100%的虚拟国际会议。总体而言,来自全球14个国家36个机构的334名注册参与者的研究人员共发表了130篇论文。FOSIC2020宣布闭幕,来自加拿大滑铁卢大学和拉各斯州立大学的团队负责人与来自不同国家的研究生组成了一个免费的技术研讨会,重点关注从脆弱性到可行性项目的V2V全球伙伴关系。所有与会者都获得了免费的电子摘要书和证书。
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引用次数: 0
A Collocation Based Block Multistep Scheme without Predictors for the Numerical Solution Parabolic Partial Differential Equations 抛物型偏微分方程数值解的无预测因子配置分块多步格式
Pub Date : 2021-01-01 DOI: 10.36108/jrrslasu/1202.80.0120
J. Ehigie
Introduction: Many life problems often result in differential equations models when formulated mathematically, particularly problems that depend on time and rates which give rise to Partial Differential Equations (PDE). Aims: In this paper, we advance the solution of some Parabolic Partial Dif-ferential Equations (PDE) using a block backward differentiation formula im-plemented in block matrix form without predictors. Materials and Methods: The block backward differentiation formula is devel-oped using the collocation method such that multiple time steps are evaluated simultaneously. Results: A five-point block backward differentiation formula is developed. The stability analysis of the methods reveals that the method is L0 stable. Conclusion: The implementation of some parabolic PDEs shows that the method yields better accuracy than the celebrated Crank– Nicholson’s method.
导言:当用数学公式表述时,许多生命问题通常会产生微分方程模型,特别是依赖于时间和速率的问题,这些问题会产生偏微分方程(PDE)。目的:利用无预测因子的分块矩阵形式的分块后向微分公式,给出了一类抛物型偏微分方程的解。材料与方法:采用多时间步长同时求值的搭配法,建立了分块后向微分公式。结果:建立了一个五点块逆向微分公式。对方法的稳定性分析表明,该方法是L0稳定的。结论:对一些抛物型偏微分方程的实现表明,该方法比著名的克兰克-尼克尔森方法具有更好的精度。
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引用次数: 0
Heavy-metals accumulation in five demersal marine species from Nigerian coastal waters (Eastern Central Atlantic, FAO Area 34) 尼日利亚沿海水域(中大西洋东部,粮农组织第34区)五种底栖海洋物种的重金属积累
Pub Date : 2021-01-01 DOI: 10.36108/jrrslasu/1202.80.0110
A. Adeboyejo
The study was conducted on heavy-metals accumulation in five demersal marine species from the Nigerian coastal water (FAO, Area 34) to ascertain the bio-integrity and safety of the Sea foods for export. Five hundred and six (506) specimens (Parapenaeopsis atlantica, Penaeus monodon, Penaeus notialis, Portunus validus and Cynoglossus browni). were sampled from 32 fishing trawlers owned by a reputable private company and assessed fresh for biological (morphometric data) and heavy metals analysis (In-vivo) using 210 Atomic Absorption Spectrophotometer (AAS). Study revealed the Mean weight (Mean±SD) of P. atlantica, P. monodon, P. notialis, P. validus and C. browni were: 9.42 ±0.26, 96.79 ± 2.38, 26.82 ± 1.34, 284.09 ± 7.34 and 411.09 ± 15.27g respectively. Heavy-metal accumulated in the muscles (mg/kg) showed Lead (Pb): 0.15 ± 0.05 for P. atlantica; 0.12 ± 0.06 for P. monodon; 0.15 ± 0.02 for P. notialis; 0.14 ± 0.07 for C. browni; and 0.14 ± 0.08 for P. validus. Iron (Fe) revealed: 2.7 ±0.07, 2.26 ± 0.06, 2.32 ± 0.08, 2.43 ± 0.12, and 2.42 ± 0.09 respectively. Zinc (Zn) also showed: 8.68 ± 0.12, 8.97 ± 0.14, 9.13 ± 0.12, 8.99 ± 0.11 and 8.86 ± 0.08 respectively. Zn and Fe value for P. atlantica were above acceptable limit by FAO/WHO standard. The decreasing order of mean concentrations was Zn>Fe>Pb. Arsenic (As) and Cadmium (Cd) had values of <0.01 for all the species. This report concludes that Mercury (Hg) was not detected throughout the study for all the species. But the detection of lead, iron and zinc in the muscles of species under study cast grey light on the integrity and safety of the fish species and thus relevant agencies are required to respond to reduce this trend for the safety of humans.
对尼日利亚沿海水域(粮农组织,第34区)的五种底栖海洋物种的重金属积累进行了研究,以确定用于出口的海洋食品的生物完整性和安全性。556个(506个)标本(大西洋副青虾、单对虾、北方对虾、有效对虾和褐舌舌对虾)。从一家信誉良好的私营公司拥有的32艘拖网渔船上取样,并使用210原子吸收分光光度计(AAS)对生物(形态计量数据)和重金属分析(体内)进行了新鲜评估。研究结果表明,大西洋p、单叶p、野p、白p和褐p的平均体重(Mean±SD)分别为9.42±0.26、96.79±2.38、26.82±1.34、284.09±7.34和411.09±15.27g。肌肉中重金属积累量(mg/kg):大西洋鲈的铅(Pb): 0.15±0.05;单胞假单胞菌为0.12±0.06;牡丹0.15±0.02;褐鳟为0.14±0.07;为0.14±0.08。铁(Fe)分别为:2.7±0.07、2.26±0.06、2.32±0.08、2.43±0.12和2.42±0.09。锌(Zn)值分别为8.68±0.12、8.97±0.14、9.13±0.12、8.99±0.11和8.86±0.08。大西洋蒿的锌、铁含量均高于FAO/WHO标准的可接受限值。平均浓度递减顺序为Zn>Fe>Pb。砷(As)和镉(Cd)值均<0.01。该报告的结论是,在整个研究过程中,并没有在所有物种中检测到汞。但是,在所研究的鱼类肌肉中检测到铅、铁和锌,这使人们对鱼类的完整性和安全性产生了不确定的看法,因此需要有关机构作出反应,以减少这种趋势,以保障人类的安全。
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