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Implementation and Evaluation of a Protocol for the Management of Type C Tracheoesophageal Fistula C型气管食管瘘治疗方案的实施与评价。
IF 1.7 3区 医学 Q2 SURGERY Pub Date : 2026-03-01 Epub Date: 2026-02-10 DOI: 10.1016/j.jss.2026.01.010
Sage A. Vincent MD , Lori Silveira PhD, MS , Samantha Bothwell MS , Jonathan Roach MD , Jose Diaz-Miron MD, MSCS , Stephanie L. Bourque MD, MSCS , Shannon N. Acker MD

Introduction

A multidisciplinary protocol for the management of esophageal atresia/tracheoesophageal fistula (EA/TEF) was developed with stakeholders from pediatric surgery and neonatology. Introduced in July 2022, this study aims to assess protocol utilization and association with patient outcomes.

Methods

We performed a single-center, retrospective review of neonatal patients who underwent type C EA/TEF repair between 2010 and 2024. Utilization of protocol elements was assessed, as well as clinical outcomes. Preprotocol and postprotocol management and outcomes were compared using logistic regression. A prospective provider survey was administered to assess protocol sustainability and knowledge.

Results

There were 103 patients who underwent type C EA/TEF repair, 87 preprotocol and 16 postprotocol implementation. Thoracoscopic repair was more common postprotocol (68.8% versus 31.0%, P = 0.003). Patients were more likely to receive total parenteral nutrition until full enteral feeds were reached (odds ratio 75.6; 95% confidence interval 4.2, 1445; P = 0.003) and receive enteral feeds within 24 h of surgery when transanastomotic tube was in place (odds ratio 3.71; 95% confidence interval 1.04, 13.27; P = 0.043) postprotocol. There was no significant change in outcomes including anastomotic leak and stricture. Providers could correctly identify 2/3 of the EA/TEF protocol elements and 22% reported receiving education on its contents.

Conclusions

Implementation of an EA/TEF protocol was associated with a 75 times greater likelihood of patients receiving total parenteral nutrition until full feeds were reached and 3.7 times greater likelihood of starting enteral feeds within 24 h of surgery when transanastomotic tube was in place. There was a shift toward thoracoscopic repair of EA/TEF and no change in clinical outcomes including anastomotic leak and stricture. Implementation and knowledge of the protocol faced challenges and provider surveys identified avenues for improving education strategies.
来自儿科外科和新生儿科的利益相关者制定了一项多学科的食管闭锁/气管食管瘘(EA/TEF)治疗方案。该研究于2022年7月推出,旨在评估方案的使用及其与患者预后的关联。方法:我们对2010年至2024年间接受C型EA/TEF修复的新生儿患者进行了单中心回顾性研究。评估方案要素的使用情况以及临床结果。采用逻辑回归比较方案前和方案后的管理和结果。对潜在提供者进行调查,以评估协议的可持续性和知识。结果:103例患者行C型EA/TEF修复,方案前87例,方案后16例。术后胸腔镜修复更为常见(68.8%比31.0%,P = 0.003)。患者接受全肠外营养的可能性更大,直到完全肠内喂养(优势比75.6;95%可信区间4.2,1445;P = 0.003),术后24小时内放置吻合口管后接受肠内喂养的可能性更大(优势比3.71;95%可信区间1.04,13.27;P = 0.043)。吻合口瘘和狭窄等预后无明显变化。提供者可以正确识别2/3的EA/TEF协议元素,22%的人报告接受了有关其内容的教育。结论:实施EA/TEF方案与患者接受全肠外营养的可能性增加75倍,直到达到全喂养的可能性增加3.7倍,在手术后24小时内开始肠内喂养,经吻合口管到位。手术转向胸腔镜下修复EA/TEF,临床结果无变化,包括吻合口漏和狭窄。协议的实施和知识面临挑战,提供者调查确定了改进教育战略的途径。
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引用次数: 0
Assessing the Association of Age and Preoperative Sodium Level on Colectomy Outcomes: An NSQIP Study 评估年龄和术前钠水平与结肠切除术结果的关系:一项NSQIP研究
IF 1.7 3区 医学 Q2 SURGERY Pub Date : 2026-03-01 Epub Date: 2026-02-12 DOI: 10.1016/j.jss.2026.01.012
Amandeep S. Ahluwalia BS, Hari Ramesh MS, Zummar Asad MB, BCh, BAO, Alex I. Halpern MD, Matthew Ng MD, Susan Kartiko MD, PhD, FACS

Introduction

Preoperative abnormal sodium level is suggested to increase mortality risk in surgeries, including colectomy for colorectal cancer. However, it remains unclear which age groups are most affected by this electrolyte derangement. To bridge this gap and to better risk stratify patients preoperatively, we assessed the association of age on patients with abnormal sodium level undergoing colectomy for colorectal cancer.

Materials and Methods

We reviewed the American College of Surgeons National Safety Quality Improvement Program Procedure-Targeted Colectomy database from 2015-2020, identifying patients over the age of 18 who underwent colectomy for primary colon cancer. We dichotomized the group by age, either younger than or 65 y and older. We collected demographics, comorbidities, laboratory values, and operative variables. We performed descriptive statistics, univariate analysis, and multivariable logistic regression with interaction term analysis. Our primary outcome was the relationship between age and 30-d mortality among patients with abnormal sodium levels. We defined statistical significance using two-sided tests as P < 0.05.

Results

We identified 89,745 patients who underwent colectomy for primary colon cancer, 50,528 of those were aged 65 y and older. On multivariate analysis, we found that age ≥65 y is associated with an increased risk of mortality (odds ratio [OR], 2.574, P < 0.01). We found sodium level to have a U-shaped relationship with increased risk of mortality for both hyponatremia and hypernatremia (hyponatremia OR, 1.38, P < 0.01, hypernatremia OR, 1.878, P < 0.01), controlling for demographics and comorbidities. On multivariate interaction analysis, sodium level did not pose a clinically significant higher mortality risk to patients' age (OR, 1.002, P < 0.01).

Conclusions

Advanced age and abnormal sodium level are independently associated with 30-d mortality following colectomy for colon cancer. Furthermore, the association between abnormal sodium levels and mortality does not differ in a clinically meaningful way between younger and older patients. This finding reinforces that abnormal sodium level is associated with an increased mortality risk after colectomy for colon cancer and provides a potential target for further study.
术前钠水平异常可增加手术死亡风险,包括结直肠癌结肠切除术。然而,目前尚不清楚哪些年龄组受这种电解质紊乱的影响最大。为了弥补这一差距,并在术前更好地对患者进行风险分层,我们评估了年龄与接受结直肠癌结肠切除术的钠水平异常患者的关系。材料和方法我们回顾了2015-2020年美国外科医师学会国家安全质量改进计划程序-结肠切除术数据库,确定了18岁以上因原发性结肠癌接受结肠切除术的患者。我们按年龄将这组人分成两组,一组小于65岁,另一组大于65岁。我们收集了人口统计学、合并症、实验室值和手术变量。我们进行了描述性统计、单变量分析和多变量逻辑回归与交互项分析。我们的主要结局是钠水平异常患者的年龄与30天死亡率之间的关系。采用双侧检验P <; 0.05定义统计学显著性。结果我们确定了89745例因原发性结肠癌接受结肠切除术的患者,其中50528例年龄在65岁及以上。在多因素分析中,我们发现年龄≥65岁与死亡风险增加相关(优势比[OR], 2.574, P < 0.01)。我们发现钠水平与低钠血症和高钠血症的死亡风险增加呈u型关系(低钠血症OR, 1.38, P < 0.01,高钠血症OR, 1.878, P < 0.01),控制了人口统计学和合并症。在多因素相互作用分析中,钠水平对患者年龄的死亡风险没有临床显著性升高(OR, 1.002, P < 0.01)。结论高龄和钠水平异常与结肠癌结肠切除术后30 d死亡率独立相关。此外,钠水平异常与死亡率之间的关联在年轻和老年患者之间没有临床意义上的差异。这一发现加强了钠水平异常与结肠癌结肠切除术后死亡风险增加相关,并为进一步研究提供了潜在的目标。
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引用次数: 0
Journal of Surgical Research 外科研究杂志
IF 1.7 3区 医学 Q2 SURGERY Pub Date : 2026-03-01 Epub Date: 2026-03-07 DOI: 10.1016/S0022-4804(26)00070-3
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引用次数: 0
Reasons for Women Surgeon Attrition From the US Workforce 美国女性外科医生减少的原因
IF 1.7 3区 医学 Q2 SURGERY Pub Date : 2026-03-01 Epub Date: 2026-02-03 DOI: 10.1016/j.jss.2026.01.003
Elisa Bass BA , Richard Butterfield MA , Ruth Bush MD, JD, MPH , Linda Harris MD , Palma Shaw MD , Kellie Brown MD , Ellen Julian PhD , Sarah McLaughlin MD , Young Erben MD

Introduction

With a projected shortage of over 30,000 surgeons by 2034, understanding and reducing nonretirement attrition is critical to maintaining a sustainable surgical workforce. Prior studies show higher attrition rates among women surgeons but have limited insight into the reasons behind these decisions. This study aims to identify the factors contributing to consideration of workforce attrition among women surgeons and to highlight modifiable elements that may support retention.

Methods

An anonymous online survey was distributed to the Association of Women Surgeons email list and women surgeons’ WhatsApp groups between October and December 2024. Respondents were asked whether they had considered leaving the surgical workforce for reasons unrelated to retirement and about factors contributing to both their consideration of leaving and their decision to remain. Responses were analyzed using descriptive statistics and chi-square tests.

Results

The response rate was 15%. Of 371 total female respondents, 242 (65%) reported having considered or currently considering leaving surgery. The top reasons cited were poor work-life balance (71%), overly demanding work (57%), and discrimination or mistreatment (50%), among whom 96% reported gender-based discrimination. Primary factors for staying included financial necessity (61%), good patient relationships (60%), and collegial support (54%). Among those who considered but decided not to leave, improved work-life balance (43%), increased compensation (26%), and improved workplace relationships (26%) were the most common influences.

Conclusions

Attrition among women surgeons stems from systemic challenges. Interventions targeting work-life balance, compensation, and workplace inclusion may meaningfully support retention and help sustain a diverse and effective surgical workforce.
到2034年,预计将有超过30,000名外科医生短缺,了解和减少非退休人员流失对于维持可持续的外科劳动力至关重要。先前的研究表明,女性外科医生的流失率更高,但对这些决定背后的原因了解有限。本研究旨在确定影响女性外科医生劳动力流失的因素,并强调可能支持保留的可修改因素。方法:于2024年10月至12月向女外科医生协会电子邮件列表和女外科医生WhatsApp群进行匿名在线调查。受访者被问及他们是否考虑过因与退休无关的原因离开外科工作队伍,以及导致他们考虑离开和决定留下的因素。采用描述性统计和卡方检验对反应进行分析。结果:有效率为15%。在371名女性受访者中,242名(65%)表示曾考虑或正在考虑放弃手术。最主要的原因是工作与生活不平衡(71%),工作要求过高(57%),以及歧视或虐待(50%),其中96%的人表示存在性别歧视。留下来的主要因素包括经济需要(61%)、良好的患者关系(60%)和大学支持(54%)。在那些考虑过但决定不离开的人中,改善工作与生活的平衡(43%)、增加薪酬(26%)和改善职场关系(26%)是最常见的影响因素。结论:女性外科医生的磨耗源于系统性挑战。针对工作与生活平衡、薪酬和工作场所包容性的干预措施可能会有意地支持保留并帮助维持多样化和有效的外科工作人员队伍。
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引用次数: 0
Reduction of Neuro Check Intervals in Traumatic Brain Injury Patients is Associated With Lowers Delirium Risk 减少外伤性脑损伤患者的神经检查间隔与降低谵妄风险相关
IF 1.7 3区 医学 Q2 SURGERY Pub Date : 2026-03-01 Epub Date: 2026-01-30 DOI: 10.1016/j.jss.2026.01.007
Jayati Atahar MBBS, MPH , Jeremy Hayward MD , Alex I. Halpern MD , Ahmed Noureldin MD , Stephanie Boese MSN, RN, CCRN, TCRN , Susan Kartiko MD, PhD, FACS
<div><h3>Introduction</h3><div>Delirium is a common finding among patients with traumatic brain injuries (TBIs). Lack of sleep has been identified as contributing factors to the development of delirium. However, TBI patients in the intensive care unit (ICU) often undergo every-hour neurologic examinations (Q1 neuro checks) that disrupt their sleep. We sought to better understand the association between Q1 neuro check duration and delirium in ICU TBI patients. We hypothesize that shorter duration of Q1 neuro checks in TBI patients would be associated with fewer delirium diagnosis delirium without increased complications.</div></div><div><h3>Methods</h3><div>We performed a single-institution retrospective cohort analysis of ICU patients with TBI who underwent Q1 neuro checks at a level 1 trauma center from December 2021 to July 2023. We excluded minors and patients who died within 24 h of admission, and patients with catastrophic brain injury incompatible with life. We divided the cohort between those who underwent Q1 neuro checks for less than 24 h and those who underwent Q1 neuro checks for greater than 24 h. We used univariate and multivariate analyses to evaluate our primary outcome, delirium. Delirium diagnosis was done by the ICU clinicians based on the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition criteria. We used multivariate logistic and linear regression models to analyze unplanned return to ICU, intracranial rebleed, other complications, mortality, hospital and ICU length of stay (LOS), and a Cox proportional hazards model to analyze the hazard ratios for all the complications and death.</div></div><div><h3>Results</h3><div>We identified 153 patients, 93 underwent Q1 neuro checks for less than 24 h and 60 underwent Q1 neuro checks for greater than 24 h. On univariate analysis, there was not a significant difference in rates of delirium between the groups who underwent Q1 neuro checks for less than 24 h and for greater than 24 h (odds ratio [OR] 2.15; 95% confidence interval [CI] 0.79-5.91, <em>P</em> = 0.14). However, on multivariate analysis, after controlling patient demographics, initial Glasgow Coma Scale (GCS), Injury Severity Score, injury status, ventilation requirement, and presence of complications; patients undergoing Q1 neuro checks for more than 24 h had a statistically significant increased risk of delirium (OR 9.73; 95% CI 1.14-82.90, <em>P</em> < 0.05), mortality (OR 17.11; 95% CI 1.72-170.77, <em>P</em> < 0.05), and ICU LOS (2.57 days; 95% CI 1.23-3.92, <em>P</em> < 0.05) compared to the Q1 ≤ 24 h group. There was no significant difference in overall complications between the two groups (hazard ratio = 1.52, 95% CI 0.76-3.06, <em>P</em> = 0.24).</div></div><div><h3>Conclusions</h3><div>This study found that Q1 neuro checks for more than 24 h for TBI patients were associated with a significantly increased risk of delirium, mortality, and ICU LOS with no significant increase in overall complic
谵妄是外伤性脑损伤(tbi)患者的常见症状。睡眠不足被认为是导致谵妄的一个因素。然而,重症监护病房(ICU)的TBI患者通常每小时进行一次神经系统检查(Q1神经检查),这会扰乱他们的睡眠。我们试图更好地了解ICU TBI患者Q1神经检查时间与谵妄之间的关系。我们假设较短的TBI患者Q1神经检查时间与较少的谵妄诊断相关,谵妄没有增加并发症。方法对2021年12月至2023年7月在一级创伤中心接受Q1神经检查的ICU TBI患者进行单机构回顾性队列分析。我们排除了未成年人和入院24小时内死亡的患者,以及与生活不相容的灾难性脑损伤患者。我们将队列分为接受Q1神经检查少于24小时和接受Q1神经检查超过24小时的两组。我们使用单变量和多变量分析来评估我们的主要结局——谵妄。谵妄诊断由ICU临床医生根据《精神障碍诊断与统计手册》第5版标准进行。我们采用多变量logistic和线性回归模型分析意外返回ICU、颅内再出血、其他并发症、死亡率、住院和ICU住院时间(LOS),并采用Cox比例风险模型分析所有并发症和死亡的风险比。结果153例患者中,93例患者Q1神经检查时间小于24小时,60例患者Q1神经检查时间大于24小时。单因素分析显示,Q1神经检查时间小于24小时和大于24小时的两组患者谵妄发生率无显著差异(优势比[OR] 2.15; 95%可信区间[CI] 0.79-5.91, P = 0.14)。然而,在多变量分析中,在控制了患者人口统计学、初始格拉斯哥昏迷量表(GCS)、损伤严重程度评分、损伤状态、通气需求和并发症的存在后;与Q1≤24 h组相比,接受Q1神经检查超过24 h的患者谵妄(OR 9.73, 95% CI 1.14-82.90, P < 0.05)、死亡率(OR 17.11, 95% CI 1.72-170.77, P < 0.05)和ICU LOS(2.57天,95% CI 1.23-3.92, P < 0.05)的风险增加具有统计学意义。两组总并发症发生率差异无统计学意义(风险比= 1.52,95% CI 0.76-3.06, P = 0.24)。本研究发现,TBI患者超过24小时的Q1神经检查与谵妄、死亡率和ICU LOS的风险显著增加相关,但总体并发症无显著增加。需要对更大的患者群体进行进一步的研究来证实这些结果,并更好地了解哪些TBI患者将从较短的Q1神经检查时间中受益。
{"title":"Reduction of Neuro Check Intervals in Traumatic Brain Injury Patients is Associated With Lowers Delirium Risk","authors":"Jayati Atahar MBBS, MPH ,&nbsp;Jeremy Hayward MD ,&nbsp;Alex I. Halpern MD ,&nbsp;Ahmed Noureldin MD ,&nbsp;Stephanie Boese MSN, RN, CCRN, TCRN ,&nbsp;Susan Kartiko MD, PhD, FACS","doi":"10.1016/j.jss.2026.01.007","DOIUrl":"10.1016/j.jss.2026.01.007","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Introduction&lt;/h3&gt;&lt;div&gt;Delirium is a common finding among patients with traumatic brain injuries (TBIs). Lack of sleep has been identified as contributing factors to the development of delirium. However, TBI patients in the intensive care unit (ICU) often undergo every-hour neurologic examinations (Q1 neuro checks) that disrupt their sleep. We sought to better understand the association between Q1 neuro check duration and delirium in ICU TBI patients. We hypothesize that shorter duration of Q1 neuro checks in TBI patients would be associated with fewer delirium diagnosis delirium without increased complications.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;We performed a single-institution retrospective cohort analysis of ICU patients with TBI who underwent Q1 neuro checks at a level 1 trauma center from December 2021 to July 2023. We excluded minors and patients who died within 24 h of admission, and patients with catastrophic brain injury incompatible with life. We divided the cohort between those who underwent Q1 neuro checks for less than 24 h and those who underwent Q1 neuro checks for greater than 24 h. We used univariate and multivariate analyses to evaluate our primary outcome, delirium. Delirium diagnosis was done by the ICU clinicians based on the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition criteria. We used multivariate logistic and linear regression models to analyze unplanned return to ICU, intracranial rebleed, other complications, mortality, hospital and ICU length of stay (LOS), and a Cox proportional hazards model to analyze the hazard ratios for all the complications and death.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;We identified 153 patients, 93 underwent Q1 neuro checks for less than 24 h and 60 underwent Q1 neuro checks for greater than 24 h. On univariate analysis, there was not a significant difference in rates of delirium between the groups who underwent Q1 neuro checks for less than 24 h and for greater than 24 h (odds ratio [OR] 2.15; 95% confidence interval [CI] 0.79-5.91, &lt;em&gt;P&lt;/em&gt; = 0.14). However, on multivariate analysis, after controlling patient demographics, initial Glasgow Coma Scale (GCS), Injury Severity Score, injury status, ventilation requirement, and presence of complications; patients undergoing Q1 neuro checks for more than 24 h had a statistically significant increased risk of delirium (OR 9.73; 95% CI 1.14-82.90, &lt;em&gt;P&lt;/em&gt; &lt; 0.05), mortality (OR 17.11; 95% CI 1.72-170.77, &lt;em&gt;P&lt;/em&gt; &lt; 0.05), and ICU LOS (2.57 days; 95% CI 1.23-3.92, &lt;em&gt;P&lt;/em&gt; &lt; 0.05) compared to the Q1 ≤ 24 h group. There was no significant difference in overall complications between the two groups (hazard ratio = 1.52, 95% CI 0.76-3.06, &lt;em&gt;P&lt;/em&gt; = 0.24).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;This study found that Q1 neuro checks for more than 24 h for TBI patients were associated with a significantly increased risk of delirium, mortality, and ICU LOS with no significant increase in overall complic","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"319 ","pages":"Pages 10-17"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146070976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lower Household Income Is Associated With Higher Cardiac and Vascular Mortality After Endovascular Abdominal Aortic Aneurysm Repair 较低的家庭收入与血管内腹主动脉瘤修复后较高的心脏和血管死亡率相关。
IF 1.7 3区 医学 Q2 SURGERY Pub Date : 2026-03-01 Epub Date: 2026-02-16 DOI: 10.1016/j.jss.2026.01.025
Jon Vandenberg MD, Houssam Farres MD, Camilo Polania-Sandoval MD, Camila Esquetini-Vernon MD, Hennessy A. Morales-Arroyo BS, Yetzali Claudio-Medina BS, Christopher Jacobs MD, Young Erben MD
<div><h3>Introduction</h3><div>Poor abdominal aortic aneurysm (AAA) repair outcomes have been associated with socioeconomic disparities, reporting increased mortality and complication rates in more deprived areas. This single-center study evaluated disparities following endovascular aortic repair (EVAR) according to zip code-related income data.</div></div><div><h3>Methods</h3><div>We conducted a single-center retrospective cohort study between 2014 and 2024 in patients who underwent EVAR or fenestrated EVAR . The primary outcome was cardiac or vascular mortality. Median household income was based on the patient's zip code from the most recent United States census reports. Income data were divided into two groups based on the median household income (MHI). Survival analysis and Cox proportional hazards analysis were performed.</div></div><div><h3>Results</h3><div>A total of 244 patients were included and divided into two groups, low-MHI (≤$65,132) and high-MHI (>$65,132). Groups were similar regarding age, sex, body measurement, and comorbidities. Thirty-day aortic-related complications (low-MHI: 3.3%, high-MHI: 1.6%; <em>P</em> = 0.41) and nonaortic-related complications (low-MHI: 2.5%, high-MHI: 3.3%; <em>P</em> = 0.70) were similar between groups. Mean follow-up time was 2.6 ± 2.4 y. Mid-term aortic-related complications (low-MHI: 10.7%, high-MHI: 13.1%; <em>P</em> = 0.55) were not different between groups, as well as reintervention rates (low-MHI: 11.5%, high-MHI: 13.1%; <em>P</em> = 0.70) were similar. All-cause mortality rates were similar (low-MHI: 23.8%, high-MHI: 21.3%; <em>P</em> = 0.65); however, cardiac or vascular mortality was significantly higher in low-MHI patients (9.0% <em>versus</em> 1.6%, <em>P</em> = 0.01). This difference persisted when comparing time-to-event Kaplan-Meier curves (log-rank test <em>P</em> = 0.01). In the multivariate Cox regression analysis, age (adjusted hazard ratio: 1.12, 95% confidence interval: 1.03-1.22; <em>P</em> = 0.01) and low-MHI (adjusted hazard ratio : 5.29, 95% confidence interval: 1.14-24.48; <em>P</em> = 0.03) remained as significant predictors for cardiac or vascular mortality at follow-up. Cohorts were separated into household income quartiles and quintiles. Regarding the main outcome, a persistent significant difference in cardiac or vascular mortality rates within quartiles was present (quartile 1: 6.6%, quartile 2: 11.5%, quartile 3: 0.0%, quartile 4: 3.3%; <em>P</em> = 0.03); however, this difference was no longer significant when the data were stratified into quintiles (quintile 1: 6.1%, quintile 2: 10.3%, quintile 3: 3.4%, quintile 4: 4.1%, quintile 5: 0.0%; <em>P</em> = 0.15).</div></div><div><h3>Conclusions</h3><div>Lower household income is associated with increased cardiac or vascular mortality when stratified in both dichotomic distribution and quartiles. Further association was not present when income was stratified into quintiles, likely from loss of statistical power. Furth
腹主动脉瘤(AAA)修复效果差与社会经济差异有关,在更贫困的地区,死亡率和并发症发生率增加。这项单中心研究根据邮政编码相关的收入数据评估血管内主动脉修复(EVAR)后的差异。方法:我们在2014年至2024年间对接受EVAR或开窗EVAR的患者进行了单中心回顾性队列研究。主要结局是心脏或血管死亡率。家庭收入中位数是根据最近美国人口普查报告中患者的邮政编码计算的。收入数据根据家庭收入中位数(MHI)分为两组。进行生存分析和Cox比例风险分析。结果:共纳入244例患者,分为低mhi组(≤65,132美元)和高mhi组(>$65,132)。各组在年龄、性别、体重测量和合并症方面相似。30天主动脉相关并发症(低mhi: 3.3%,高mhi: 1.6%, P = 0.41)和非主动脉相关并发症(低mhi: 2.5%,高mhi: 3.3%, P = 0.70)组间相似。平均随访时间为2.6±2.4 y,中期主动脉相关并发症(低mhi: 10.7%,高mhi: 13.1%, P = 0.55)组间无差异,再干预率(低mhi: 11.5%,高mhi: 13.1%, P = 0.70)组间无差异。全因死亡率相似(低mhi: 23.8%,高mhi: 21.3%; P = 0.65);然而,低mhi患者的心脏或血管死亡率明显更高(9.0%比1.6%,P = 0.01)。当比较时间-事件Kaplan-Meier曲线时,这种差异仍然存在(log-rank检验P = 0.01)。在多因素Cox回归分析中,年龄(校正风险比:1.12,95%可信区间:1.03-1.22,P = 0.01)和低mhi(校正风险比:5.29,95%可信区间:1.14-24.48,P = 0.03)仍然是随访时心脏或血管死亡率的显著预测因素。队列被分为家庭收入四分位数和五分位数。关于主要结局,心脏或血管死亡率在四分位数内存在持续的显著差异(四分位数1:6.6%,四分位数2:11.5%,四分位数3:0.0%,四分位数4:3.3%,P = 0.03);然而,当数据被分成五分位数(1分位数为6.1%,2分位数为10.3%,3分位数为3.4%,4分位数为4.1%,5分位数为0.0%;P = 0.15)时,这种差异不再显著。结论:在二分分布和四分位数分层时,较低的家庭收入与心脏或血管死亡率增加有关。当收入被分成五分位数时,进一步的关联不存在,可能是由于统计能力的丧失。进一步的研究需要增加和均匀分布的队列,以更好地确定临床和公共卫生影响。
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引用次数: 0
Association of Unplanned ICU Admission and Clinical Outcomes in Trauma Patients With Severe Sepsis 创伤合并严重脓毒症患者非计划入住ICU与临床结局的关系。
IF 1.7 3区 医学 Q2 SURGERY Pub Date : 2026-03-01 Epub Date: 2026-02-10 DOI: 10.1016/j.jss.2026.01.017
Alexander Brown MBS , Ariel Hus BS , Ian Bundschu BS , Logan Rogers BS , Yumna Indorewala BS , Alexandra Kata MS , Sanjan Kumar BS , Adel Elkbuli MD, MPH, MBA

Introduction

This study aims to evaluate the association between unplanned ICU admission and clinical outcomes in adult and geriatric trauma patients with severe sepsis. Additionally, this study assesses predictors of worsened outcomes in this population.

Methods

This retrospective cohort study analyzed the ACS-TQIP database (2017-2023) to analyze outcomes associated with unplanned ICU admission in adult and geriatric trauma patients (ISS ≥ 15) with severe sepsis. The primary outcome was in-hospital mortality, and secondary outcomes included discharge disposition, ICU-LOS, ventilator-free days, and complications.

Results

In both adult and geriatric patients, unplanned ICU admission was associated with significantly lower in-hospital mortality (aOR: 0.460, 95% CI: 0.346-0.610, P < 0.001, SE: 0.145) (aOR: 0.657, 95% CI: 0.438-0.987, P = 0.043, SE: 0.207) and more ventilator-free days (β = 5.067, 95% CI: 3.981-6.153, P < 0.001, SE: 0.554) (β = 2.402, 95% CI: 0.625-4.180, P = 0.008, SE: 0.905). Advanced age (over 64 years) (aOR: 1.487, 95% CI: 1.140-1.924, P = 0.003, SE: 0.134), ISS over 25 (aOR: 1.487, 95% CI: 1.251-1.768, P < 0.001, SE: 0.088), and having multiple comorbidities (aOR: 1.402, 95% CI: 1.152-1.706, P < 0.001, SE: 0.100) were found to be associated with worse outcomes.

Conclusions

Findings from this national analysis highlighted predictors associated with worsening outcomes in adult and geriatric trauma patients with severe sepsis. Additionally, while unplanned ICU admission was associated with improved outcomes in both adult and geriatric trauma patients with severe sepsis compared to those admitted to hospital floors, its high resource utilization emphasizes the importance of developing targeted care strategies to prevent resource overutilization and clinical deterioration in this patient population.
本研究旨在评估成人和老年创伤合并严重脓毒症患者非计划入住ICU与临床结局的关系。此外,本研究评估了该人群预后恶化的预测因素。方法:本回顾性队列研究分析ACS-TQIP数据库(2017-2023),分析合并严重脓毒症的成人和老年创伤患者(ISS≥15)非计划入住ICU的结局。主要结局是住院死亡率,次要结局包括出院处置、ICU-LOS、无呼吸机天数和并发症。结果:在成人和老年患者中,非计划入住ICU与较低的住院死亡率(aOR: 0.460, 95% CI: 0.346-0.610, P < 0.001, SE: 0.145) (aOR: 0.657, 95% CI: 0.438-0.987, P = 0.043, SE: 0.207)和较长的无呼吸机天数(β = 5.067, 95% CI: 3.981-6.153, P < 0.001, SE: 0.554) (β = 2.402, 95% CI: 0.625-4.180, P = 0.008, SE: 0.905)相关。高龄(超过64岁)(aOR: 1.487, 95% CI: 1.140-1.924, P = 0.003, SE: 0.134)、ISS超过25 (aOR: 1.487, 95% CI: 1.251-1.768, P < 0.001, SE: 0.088)和合并多种并发症(aOR: 1.402, 95% CI: 1.152-1.706, P < 0.001, SE: 0.100)与预后较差相关。结论:这项全国性分析的结果强调了与成人和老年创伤患者严重败血症预后恶化相关的预测因素。此外,虽然与住院相比,非计划ICU住院与成人和老年创伤严重脓毒症患者的预后改善有关,但其高资源利用率强调了制定有针对性的护理策略的重要性,以防止该患者群体的资源过度利用和临床恶化。
{"title":"Association of Unplanned ICU Admission and Clinical Outcomes in Trauma Patients With Severe Sepsis","authors":"Alexander Brown MBS ,&nbsp;Ariel Hus BS ,&nbsp;Ian Bundschu BS ,&nbsp;Logan Rogers BS ,&nbsp;Yumna Indorewala BS ,&nbsp;Alexandra Kata MS ,&nbsp;Sanjan Kumar BS ,&nbsp;Adel Elkbuli MD, MPH, MBA","doi":"10.1016/j.jss.2026.01.017","DOIUrl":"10.1016/j.jss.2026.01.017","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aims to evaluate the association between unplanned ICU admission and clinical outcomes in adult and geriatric trauma patients with severe sepsis. Additionally, this study assesses predictors of worsened outcomes in this population.</div></div><div><h3>Methods</h3><div>This retrospective cohort study analyzed the ACS-TQIP database (2017-2023) to analyze outcomes associated with unplanned ICU admission in adult and geriatric trauma patients (ISS ≥ 15) with severe sepsis. The primary outcome was in-hospital mortality, and secondary outcomes included discharge disposition, ICU-LOS, ventilator-free days, and complications.</div></div><div><h3>Results</h3><div>In both adult and geriatric patients, unplanned ICU admission was associated with significantly lower in-hospital mortality (aOR: 0.460, 95% CI: 0.346-0.610, <em>P</em> &lt; 0.001, SE: 0.145) (aOR: 0.657, 95% CI: 0.438-0.987, <em>P</em> = 0.043, SE: 0.207) and more ventilator-free days (β = 5.067, 95% CI: 3.981-6.153, <em>P</em> &lt; 0.001, SE: 0.554) (β = 2.402, 95% CI: 0.625-4.180, <em>P</em> = 0.008, SE: 0.905). Advanced age (over 64 years) (aOR: 1.487, 95% CI: 1.140-1.924, <em>P</em> = 0.003, SE: 0.134), ISS over 25 (aOR: 1.487, 95% CI: 1.251-1.768, <em>P</em> &lt; 0.001, SE: 0.088), and having multiple comorbidities (aOR: 1.402, 95% CI: 1.152-1.706, <em>P</em> &lt; 0.001, SE: 0.100) were found to be associated with worse outcomes.</div></div><div><h3>Conclusions</h3><div>Findings from this national analysis highlighted predictors associated with worsening outcomes in adult and geriatric trauma patients with severe sepsis. Additionally, while unplanned ICU admission was associated with improved outcomes in both adult and geriatric trauma patients with severe sepsis compared to those admitted to hospital floors, its high resource utilization emphasizes the importance of developing targeted care strategies to prevent resource overutilization and clinical deterioration in this patient population.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"319 ","pages":"Pages 100-107"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146165701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supply and Demand: Pediatric Surgical Specialties Fellowship Match Trends 供给和需求:儿科外科专科奖学金匹配趋势。
IF 1.7 3区 医学 Q2 SURGERY Pub Date : 2026-03-01 Epub Date: 2025-08-22 DOI: 10.1016/j.jss.2025.06.094
Nina D. Kosciuszek DO, MS , Michael Froehlich MD , Robert P. Moore MD , Maroun Yammine MD , Stephanie C. Cardamone MD , David A. Chesler MD , James M. Barsi MD , Jaime P. Doody MD , Alvin Wong MD , Michael L. Ernst MD , Richard J. Scriven MD , Kristen A. Calabro MD , Kenneth W. Gow MD, MHA
<div><h3>Introduction</h3><div>Surgical specialization is critical in medical training, with fellowships as key pathways for career advancement and shaping the pediatric surgical workforce. Given the surgical condition and procedural overlap between subspecialties, skills often complement each other to enhance comprehensive pediatric care. This study examines the balance of supply and demand across pediatric surgical fellowship positions, evaluating trends in individual fields and their collective impact on pediatric surgical care.</div></div><div><h3>Methods</h3><div>We analyzed available fellowship match data from 2004 to 2024 across nine pediatric subspecialties: anesthesiology, cardiac surgery, general surgery, gynecology, neurosurgery, orthopedics, otolaryngology, plastic surgery, and urology. Data were obtained from the National Resident Matching Program, San Francisco Match, and the Pediatric Orthopedic Society of North America. Applicant-to-position ratios were calculated, with 1 indicating balance, >1 reflecting higher demand, and <1 indicating lower demand. Statistical analysis was performed using least squares regression and ANOVA in SPSS (IBM SPSS Statistics, Version 29.0.2.0 (IBM Corp, Armonk, NY)). Data are expressed as mean ± standard deviation, where applicable.</div></div><div><h3>Results</h3><div>Nine subspecialties were assessed. Higher demand was found for available positions in pediatric general surgery (1.80 ± 0.23), gynecology (1.35 ± 0.21), and cardiac surgery (1.21 ± 0.46). Specialties with lower demand included urology (0.81 ± 0.08), plastic surgery (0.88 ± 0.13), anesthesiology (0.92 ± 0.20), otolaryngology (0.95 ± 0.14), and neurosurgery (0.96 ± 0.20). An analysis of trends revealed that all specialties experienced a decline in the ratio of applicants to available positions, except for orthopedics, which saw significant decreases in the ratios for anesthesiology, general surgery, and plastic surgery. The average number of unfilled fellowship positions was most notable for anesthesiology (35.2 ± 19.5), orthopedics (16.4 ± 5.5), and otolaryngology (11.2 ± 4.7). The percentage of unfilled positions was notably high for urology (31.9% ± 8.8%), plastic surgery (27.6% ± 11.6%), and otolaryngology (24.0% ± 9.4%).</div></div><div><h3>Conclusions</h3><div>The findings suggest that pediatric general surgery, gynecology, and cardiac surgery continue to attract strong interest, while anesthesiology, orthopedics, otolaryngology, plastic surgery, and urology are seeing fewer applicants than available positions. What is most concerning, however, is that almost all fields have witnessed a decline in interest over time. If it continues, this trend portends poorly for the future of pediatric surgical care, as an imbalance between the decreasing supply of specialists and the growing demand for specialized care could lead to gaps in patient services. Addressing these imbalances is crucial to sustaining a well-rounded, highly qualifi
导读:外科专业化在医学培训中至关重要,奖学金是职业发展和塑造儿科外科劳动力的关键途径。鉴于手术条件和亚专科之间的程序重叠,技能往往互补,以加强综合儿科护理。本研究考察了儿科外科奖学金职位的供需平衡,评估了各个领域的趋势及其对儿科外科护理的集体影响。方法:我们分析了2004年至2024年9个儿科亚专科的可用奖学金匹配数据:麻醉学、心脏外科、普外科、妇科、神经外科、骨科、耳鼻喉科、整形外科和泌尿外科。数据来自全国住院医师配对计划、旧金山配对计划和北美儿科骨科学会。计算了申请人与职位的比率,其中1表示平衡,>1反映更高的需求,结果:评估了9个亚专业。儿科普外科(1.80±0.23)、妇科(1.35±0.21)、心脏外科(1.21±0.46)的空缺需求较高。需求较低的专科包括泌尿外科(0.81±0.08)、整形外科(0.88±0.13)、麻醉科(0.92±0.20)、耳鼻喉科(0.95±0.14)、神经外科(0.96±0.20)。一项趋势分析显示,除骨科外,所有专业的申请人数与空缺职位的比例都有所下降,麻醉学、普外科和整形外科的比例明显下降。平均空缺人数以麻醉科(35.2±19.5)、骨科(16.4±5.5)和耳鼻喉科(11.2±4.7)最多。泌尿外科(31.9%±8.8%)、整形外科(27.6%±11.6%)、耳鼻喉科(24.0%±9.4%)的空缺比例较高。结论:研究结果表明,儿科普外科、妇科和心脏外科继续吸引着人们的浓厚兴趣,而麻醉科、骨科、耳鼻喉科、整形外科和泌尿科的申请人数少于空缺职位。然而,最令人担忧的是,随着时间的推移,几乎所有领域的兴趣都在下降。如果继续下去,这一趋势预示着小儿外科护理的未来很糟糕,因为专家供应减少和专业护理需求增长之间的不平衡可能导致患者服务的差距。解决这些不平衡是至关重要的,以维持一个全面的,高素质的儿科外科劳动力。
{"title":"Supply and Demand: Pediatric Surgical Specialties Fellowship Match Trends","authors":"Nina D. Kosciuszek DO, MS ,&nbsp;Michael Froehlich MD ,&nbsp;Robert P. Moore MD ,&nbsp;Maroun Yammine MD ,&nbsp;Stephanie C. Cardamone MD ,&nbsp;David A. Chesler MD ,&nbsp;James M. Barsi MD ,&nbsp;Jaime P. Doody MD ,&nbsp;Alvin Wong MD ,&nbsp;Michael L. Ernst MD ,&nbsp;Richard J. Scriven MD ,&nbsp;Kristen A. Calabro MD ,&nbsp;Kenneth W. Gow MD, MHA","doi":"10.1016/j.jss.2025.06.094","DOIUrl":"10.1016/j.jss.2025.06.094","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Introduction&lt;/h3&gt;&lt;div&gt;Surgical specialization is critical in medical training, with fellowships as key pathways for career advancement and shaping the pediatric surgical workforce. Given the surgical condition and procedural overlap between subspecialties, skills often complement each other to enhance comprehensive pediatric care. This study examines the balance of supply and demand across pediatric surgical fellowship positions, evaluating trends in individual fields and their collective impact on pediatric surgical care.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;We analyzed available fellowship match data from 2004 to 2024 across nine pediatric subspecialties: anesthesiology, cardiac surgery, general surgery, gynecology, neurosurgery, orthopedics, otolaryngology, plastic surgery, and urology. Data were obtained from the National Resident Matching Program, San Francisco Match, and the Pediatric Orthopedic Society of North America. Applicant-to-position ratios were calculated, with 1 indicating balance, &gt;1 reflecting higher demand, and &lt;1 indicating lower demand. Statistical analysis was performed using least squares regression and ANOVA in SPSS (IBM SPSS Statistics, Version 29.0.2.0 (IBM Corp, Armonk, NY)). Data are expressed as mean ± standard deviation, where applicable.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Nine subspecialties were assessed. Higher demand was found for available positions in pediatric general surgery (1.80 ± 0.23), gynecology (1.35 ± 0.21), and cardiac surgery (1.21 ± 0.46). Specialties with lower demand included urology (0.81 ± 0.08), plastic surgery (0.88 ± 0.13), anesthesiology (0.92 ± 0.20), otolaryngology (0.95 ± 0.14), and neurosurgery (0.96 ± 0.20). An analysis of trends revealed that all specialties experienced a decline in the ratio of applicants to available positions, except for orthopedics, which saw significant decreases in the ratios for anesthesiology, general surgery, and plastic surgery. The average number of unfilled fellowship positions was most notable for anesthesiology (35.2 ± 19.5), orthopedics (16.4 ± 5.5), and otolaryngology (11.2 ± 4.7). The percentage of unfilled positions was notably high for urology (31.9% ± 8.8%), plastic surgery (27.6% ± 11.6%), and otolaryngology (24.0% ± 9.4%).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;The findings suggest that pediatric general surgery, gynecology, and cardiac surgery continue to attract strong interest, while anesthesiology, orthopedics, otolaryngology, plastic surgery, and urology are seeing fewer applicants than available positions. What is most concerning, however, is that almost all fields have witnessed a decline in interest over time. If it continues, this trend portends poorly for the future of pediatric surgical care, as an imbalance between the decreasing supply of specialists and the growing demand for specialized care could lead to gaps in patient services. Addressing these imbalances is crucial to sustaining a well-rounded, highly qualifi","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"319 ","pages":"Pages 200-212"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung Cancer Screening in a Rural Academic Health System Reveals Low False-Positive Rates 农村学术卫生系统肺癌筛查显示低假阳性率
IF 1.7 3区 医学 Q2 SURGERY Pub Date : 2026-03-01 Epub Date: 2026-01-29 DOI: 10.1016/j.jss.2025.12.042
Kayla A. Fay MPH , Karen E. Schifferdecker PhD, MPH , Linda M. Kinney MPA , Ellie J. Kyung PhD , Shoshana H. Bardach PhD , Maureen B. Boardman MSN, FNP-C, FAANP , Dagmar Hoegemann Savellano MD , Connor Bridges BS , Sean R. Halloran BA , Samuel Youkilis BA , Tom Bird , Rian M. Hasson MD, MPH

Introduction

Uptake of lung cancer screening (LCS) suffers from the misconception that LCS produces high false-positive findings. The purpose of this study was to assess LCS results to better quantify these rates.

Methods

Retrospective review of patients who underwent LCS at a single, LCS-accredited rural health system from January 2017 to March 2022 was performed. Patient demographics, Lung Reporting and Data Systems (Lung-RADS) score, and follow-up data were reviewed. Using the patient's first LCS scan, the false-positive rate was calculated using Lung-RADS 3 or higher as an indication of a “positive” finding and then calculated using Lung-RADS 4B and 4X alone.

Results

Analyses included 1708 patients, and 89.9% (1536/1708) of these scans were Lung-RADS 1 or 2. Among 80 patients whose first scan resulted in Lung-RADS 3, and 54 patients with Lung-RADS 4a, 61.3% (49/80) and 48.1% (26/54), respectively, received a lower Lung-RADS score on a follow-up scan, allowing them to return to annual screening. Twenty-nine percent (11/38) of those with Lung-RADS 4B or 4X on their first scan were diagnosed with lung cancer. Among the 1708 patients, the false-positive rate on their first scan (Lung-RADS 3 or higher) was 9.4% (159/1695). The rate dropped to 1.6% (27/1695) when only Lung-RADS 4B and 4X was considered a “positive” finding.

Conclusions

Distribution of Lung-RADS scores were in line with national statistics. Results add to mounting evidence that LCS risk of false positives is comparable to mammography, which should encourage clinicians and patients to utilize this life saving screening modality.
肺癌筛查(LCS)的接受受到LCS产生高假阳性结果的误解的影响。本研究的目的是评估LCS结果,以更好地量化这些比率。方法回顾性分析2017年1月至2022年3月在LCS认证的单一农村卫生系统接受LCS治疗的患者。回顾了患者人口统计学、肺报告和数据系统(Lung- rads)评分和随访数据。使用患者的第一次LCS扫描,使用Lung-RADS 3或更高作为“阳性”发现的指示来计算假阳性率,然后单独使用Lung-RADS 4B和4X计算假阳性率。结果纳入1708例患者,89.9%(1536/1708)的扫描结果为Lung-RADS 1或2。在80例首次扫描结果为Lung-RADS 3的患者和54例Lung-RADS 4a的患者中,61.3%(49/80)和48.1%(26/54)的患者在随访扫描中获得了较低的Lung-RADS评分,允许他们返回年度筛查。29%(11/38)的肺癌rads 4B或4X患者在第一次扫描时被诊断为肺癌。在1708例患者中,首次扫描(Lung-RADS 3或更高)的假阳性率为9.4%(159/1695)。当只有Lung-RADS 4B和4X被认为是“阳性”发现时,该比率降至1.6%(27/1695)。结论肺- rads评分分布符合国家统计数据。越来越多的证据表明,LCS假阳性的风险与乳房x光检查相当,这应该鼓励临床医生和患者利用这种挽救生命的筛查方式。
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引用次数: 0
Ten-Year Single-Center Experience in the Surgical Treatment of Carotid Body Tumors 颈动脉体肿瘤外科治疗的十年单中心经验。
IF 1.7 3区 医学 Q2 SURGERY Pub Date : 2026-03-01 Epub Date: 2026-02-10 DOI: 10.1016/j.jss.2026.01.014
Antonio Bozzani MD , Simone Mauramati MD , Vittorio Arici MD , Elvira Visciglia MD , Matteo Crippa MD , Rosa Rossini MD , Marco Benazzo MD , Antonio V. Sterpetti MD , Patrizia Morbini MD , Eloisa Arbustini MD

Introduction

This study aimed to evaluate outcomes in the surgical management of carotid body tumors (CBTs), assess long-term follow-up, and examine the importance of genetic testing for succinate dehydrogenase genes.

Materials and Methods

We retrospectively reviewed 36 patients who had undergone resection of CBTs at our institution from 2013 to 2024. Data on patient history, symptoms, clinical features, diagnostic procedures, treatment modality, perioperative and late (persistent neurological disability and recurrence rate) complications, histological findings, DNA test, and secretory activity were analyzed.

Results

The average tumor size was 34.1 mm. A familial history of head and neck paragangliomas was present in 7 patients. According to the Shamblin classification, we observed 8/38 (21%) type III, 18/38 (47.4%) type II, and 12/38 (31.6) type I CBTs. Malignancy was present in two patients. No postoperative deaths or strokes occurred. Cranial nerve injury occurred in 8 patients (22.2%). Tumor size greater than 4 cm and Shamblin grade 3 were correlated with cranial nerve complications. The average follow-up period was 112.4 mo (range: 15-169 mo), including yearly clinical evaluations with Doppler carotid ultrasound. During this period, we observed 3 local recurrences and 1 new intrathoracic localization of paraganglioma.

Conclusions

Surgery is recommended for all patients with CBT and fit for open surgery. Early detection of small tumors may improve surgical outcomes and reduce complications.
本研究旨在评估颈动脉体肿瘤(CBTs)手术治疗的结果,评估长期随访,并检查琥珀酸脱氢酶基因检测的重要性。材料和方法:我们回顾性分析了2013年至2024年在我院行cbt切除术的36例患者。分析患者病史、症状、临床特征、诊断程序、治疗方式、围手术期和晚期(持续性神经功能障碍和复发率)并发症、组织学结果、DNA检测和分泌活性等数据。结果:肿瘤平均大小为34.1 mm。7例患者有头颈部副神经节瘤的家族史。根据Shamblin分类,我们观察到8/38(21%)为III型,18/38(47.4%)为II型,12/38(31.6)为I型cbt。2例患者存在恶性肿瘤。无术后死亡或中风发生。颅神经损伤8例(22.2%)。肿瘤大小大于4cm和Shamblin分级3级与脑神经并发症相关。平均随访时间为112.4个月(范围:15-169个月),包括每年多普勒颈动脉超声临床评估。在此期间,我们观察到3例局部复发和1例新的胸内副神经节瘤。结论:所有CBT患者均推荐手术治疗,适合开腹手术。早期发现小肿瘤可以改善手术效果,减少并发症。
{"title":"Ten-Year Single-Center Experience in the Surgical Treatment of Carotid Body Tumors","authors":"Antonio Bozzani MD ,&nbsp;Simone Mauramati MD ,&nbsp;Vittorio Arici MD ,&nbsp;Elvira Visciglia MD ,&nbsp;Matteo Crippa MD ,&nbsp;Rosa Rossini MD ,&nbsp;Marco Benazzo MD ,&nbsp;Antonio V. Sterpetti MD ,&nbsp;Patrizia Morbini MD ,&nbsp;Eloisa Arbustini MD","doi":"10.1016/j.jss.2026.01.014","DOIUrl":"10.1016/j.jss.2026.01.014","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to evaluate outcomes in the surgical management of carotid body tumors (CBTs), assess long-term follow-up, and examine the importance of genetic testing for succinate dehydrogenase genes.</div></div><div><h3>Materials and Methods</h3><div>We retrospectively reviewed 36 patients who had undergone resection of CBTs at our institution from 2013 to 2024. Data on patient history, symptoms, clinical features, diagnostic procedures, treatment modality, perioperative and late (persistent neurological disability and recurrence rate) complications, histological findings, DNA test, and secretory activity were analyzed.</div></div><div><h3>Results</h3><div>The average tumor size was 34.1 mm. A familial history of head and neck paragangliomas was present in 7 patients. According to the Shamblin classification, we observed 8/38 (21%) type III, 18/38 (47.4%) type II, and 12/38 (31.6) type I CBTs. Malignancy was present in two patients. No postoperative deaths or strokes occurred. Cranial nerve injury occurred in 8 patients (22.2%). Tumor size greater than 4 cm and Shamblin grade 3 were correlated with cranial nerve complications. The average follow-up period was 112.4 mo (range: 15-169 mo), including yearly clinical evaluations with Doppler carotid ultrasound. During this period, we observed 3 local recurrences and 1 new intrathoracic localization of paraganglioma.</div></div><div><h3>Conclusions</h3><div>Surgery is recommended for all patients with CBT and fit for open surgery. Early detection of small tumors may improve surgical outcomes and reduce complications.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"319 ","pages":"Pages 90-99"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146165802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Journal of Surgical Research
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