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Management of Incidental Thyroid Nodules in the Pretransplant Population 移植前人群偶发甲状腺结节的处理方法
IF 1.8 3区 医学 Q2 SURGERY Pub Date : 2024-10-08 DOI: 10.1016/j.jss.2024.09.019
Patricia G. Lu MD , Patrick T. Hangge MD , Amit K. Mathur MD , Nabil Wasif MD , Zhi Ven Fong MD, PhD , Patricia A. Cronin MD , Cameron Adler MD , Frederick Chen MD , Chee-Chee H. Stucky MD

Introduction

The incidence of thyroid nodules has increased as diagnostic imaging has become more prevalent, but the management in transplant candidates, a high-risk population because of the need for chronic immunosuppression, has not been described. We sought to review our institution’s approach to thyroid nodules incidentally found during pretransplant workup.

Methods

A multisite retrospective review was performed of pretransplant patients with incidental thyroid nodules diagnosed between 2011 and 2021. Demographics, nodule characteristics, treatment timeline, and oncologic outcomes were collected. Patients diagnosed before and after 2017 were compared to evaluate how adoption of Thyroid Imaging Reporting and Data System and expansion of a dedicated transplant center were correlated with changes in patient management.

Results

A total of 10,340 patients underwent abdominal transplant, 236 had incidental thyroid nodules. After 2017, radiology recommendations for biopsy decreased from 39% to 29% (P = 0.174) and fewer biopsies were performed, 45%-33% (P = 0.055). Time between imaging and biopsy was significantly shorter after 2017, from 14 mo to 4 (P = 0.038). Overall time from imaging to transplant was also significantly reduced, from 31 mo to 11 (P < 0.001). Thirty-one (13.1%) patients underwent thyroid surgery before transplant and four (1.7%) patients after.

Conclusions

In the recent years, thyroid biopsy rates for thyroid incidentalomas found during pretransplant workup have decreased and more closely match imaging-based guideline recommendations. Patients who required biopsy obtained them sooner and underwent transplant surgery sooner. Guideline-driven thyroid incidentaloma workup for the pretransplant population allows for timely and appropriate cancer care while avoiding unnecessary delays in transplant.
导言:随着影像诊断技术的普及,甲状腺结节的发病率越来越高,但由于需要长期免疫抑制,甲状腺结节在移植候选者这一高风险人群中的处理方法尚未见报道。我们试图回顾本机构对移植前检查中偶然发现的甲状腺结节的处理方法:我们对 2011 年至 2021 年间偶然发现甲状腺结节的移植前患者进行了多机构回顾性检查。收集了患者的人口统计学特征、结节特征、治疗时间表和肿瘤结果。对2017年之前和之后确诊的患者进行比较,以评估甲状腺成像报告和数据系统的采用以及专用移植中心的扩建与患者管理变化的相关性:共有10340名患者接受了腹腔移植手术,其中236人偶然发现甲状腺结节。2017年后,放射科建议进行活检的比例从39%降至29%(P=0.174),活检率也从45%降至33%(P=0.055)。2017 年后,成像与活检之间的时间明显缩短,从 14 个月缩短至 4 个月(P = 0.038)。从成像到移植的总体时间也明显缩短,从31个月缩短至11个月(P 结论:从2017年开始,甲状腺活检的时间明显缩短:近年来,在移植前检查中发现的甲状腺偶发瘤的甲状腺活检率有所下降,与基于影像学的指南建议更加吻合。需要活检的患者更早接受活检,也更早接受移植手术。以指南为导向的移植前甲状腺偶发瘤检查可及时提供适当的癌症治疗,同时避免不必要的移植延误。
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引用次数: 0
Implementation of an Education Module to Improve Emergency Medical Service Provider Accuracy and Confidence in Trauma Triage 实施教育模块,提高急救医疗服务提供者在创伤分诊中的准确性和信心。
IF 1.8 3区 医学 Q2 SURGERY Pub Date : 2024-10-08 DOI: 10.1016/j.jss.2024.09.014
Rachel R. Cary BS, Jennifer E. Geller BS, Michael S. Rallo BS, Amanda L. Teichman MD, FACS, Zachary P. Englert DO, FACS, Princeton Pierre MD, Timothy Murphy MSN, RN, ACNP-BC, CEN, TCRN, FAEN, Lisa Falcon MSN, RN, TCRN, NE-BC, Mayur Narayan MD, MPH, MBA, FACS, Rachel L. Choron MD, FACS

Introduction

Prehospital triage is critical to ensure timely activation of trauma center resources. Undertriage (UT) results in higher morbidity and mortality. To minimize this risk, the American College of Surgeons Committee on Trauma recommends trauma centers aim for a UT rate below 5%. Our center has a 3-tiered triage system aimed at optimizing resource allocation. We hypothesized that a trauma triage criteria educational module (TCEM) would 1) improve emergency medical services (EMSs) provider confidence and accuracy in triage and 2) improve our UT rate.

Methods

From July to November 2022, the TCEM was presented to 8 local EMS agencies who transport patients to our Level 1 trauma center. Preclass and postclass surveys assessed EMS provider triage confidence using a Likert scale 1-5. Validated trauma scenario questions were used to measure triage accuracy. The UT rate was compared between January-May 2022 (pre-TCEM) to January-May 2023 (post-TCEM) using trauma registry data. Data were analyzed using paired Wilcoxon signed rank and t-tests.

Results

72 prehospital providers participated in TCEM, most were Caucasian (65.3%), non-Hispanic (84.7%), males (77.8%) with emergency medical technician-basic certifications (90.3%). There was a significant increase in triage confidence from pre-TCEM to post-TCEM (2 versus 5; P < 0.001) and accuracy (23.2% versus 88.9%; P < 0.001). Regression analysis did not indicate a significant difference in confidence or accuracy based on years of experience, paid or volunteer provider status, or transport volume per week. The UT rate remained stable after TCEM initiation (2.3% versus 2.0%; P < 0.669).

Conclusions

This novel community based educational program demonstrated improvements in EMS provider confidence and accuracy regarding prehospital trauma triage. Outreach programs like these are often well received by EMS, and implementation is highly reproducible at other centers.
简介:院前分流对于确保及时启动创伤中心资源至关重要。分流不足(UT)会导致更高的发病率和死亡率。为了将这种风险降至最低,美国外科学院创伤委员会建议创伤中心将UT率控制在5%以下。我们中心有一个三级分流系统,旨在优化资源分配。我们假设创伤分诊标准教育模块(TCEM)将:1)提高急救医疗服务提供者对分诊的信心和准确性;2)提高我们的UT率:方法: 2022 年 7 月至 11 月,我们向 8 家将患者送往一级创伤中心的当地急救医疗机构介绍了 TCEM。课前和课后调查采用 1-5 级李克特量表评估急救医疗服务提供者的分诊信心。经过验证的创伤情景问题用于衡量分诊准确性。利用创伤登记数据,比较了 2022 年 1 月至 5 月(TCEM 前)和 2023 年 1 月至 5 月(TCEM 后)的UT 率。数据采用配对 Wilcoxon 符号秩和 t 检验进行分析:72名院前医疗人员参与了TCEM,其中大多数为白种人(65.3%)、非西班牙裔(84.7%)、男性(77.8%),拥有急救医疗技术员基础证书(90.3%)。从 TCEM 前到 TCEM 后,对分诊的信心有了明显提高(2 对 5;P 结论:这是一项基于社区的新型教育计划:这项以社区为基础的新颖教育项目提高了急救医疗服务提供者对院前创伤分诊的信心和准确性。类似这样的推广计划通常会受到急救医疗服务的欢迎,而且在其他中心的实施具有很强的可复制性。
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引用次数: 0
Plasma Inclusive Resuscitation Is Not Associated With Coagulation Profile Changes in Burn Patients 血浆包容性复苏与烧伤患者凝血谱变化无关
IF 1.8 3区 医学 Q2 SURGERY Pub Date : 2024-10-07 DOI: 10.1016/j.jss.2024.09.013
Shane K. Mathew MD , Tuan D. Le MD, DrPH , Anthony E. Pusateri PhD , Desiree N. Pinto MD , Bonnie C. Carney PhD , Melissa M. McLawhorn RN, BSN , Shawn Tejiram MD , Taryn E. Travis MD , Lauren T. Moffatt PhD , Jeffrey W. Shupp MD

Introduction

Dynamically titrated crystalloids are the standard of care for burn shock resuscitation. There are theoretical concerns that the adjunctive use of allogeneic plasma may perturb the patient's coagulation and inflammation status deleteriously. It was hypothesized that plasma-inclusive resuscitation (PIR) would not be associated with prothrombotic changes relative to baseline after thermal injury.

Methods

Patients admitted to a regional burn center who were treated with PIR as part of their burn resuscitation were enrolled. Whole blood samples were analyzed prospectively via rapid thromboelastography and rotational thromboelastometry to assess for coagulopathy at four time points throughout their acute burn resuscitation. The mixed-effect model for repeated measures followed by Tukey's post hoc test for comparisons was used to examine group differences.

Results

There were 35 patients in the analysis. Most were male (74.3%) with a median age of 43 y (32-55), concomitant inhalation injury of 28.6%, total body surface area burn size of 34% (27%-48.5%), and the overall mortality of the cohort was 28.6%. There were no transfusion reactions or thrombotic events. There were no differences in thromboelastography or rotational thromboelastometry parameters overall or when stratified by mortality, total body surface area burn, and inhalation injury. There were no significant differences between the fibrinolytic phenotypes over time.

Conclusions

Data suggest that PIR was not associated with prothrombotic or lytic changes in burn patients relative to baseline. Further research is needed to confirm these findings and evaluate efficacy of PIR in acute burn resuscitation.
简介:动态滴定晶体液是烧伤休克复苏的标准护理方法。理论上有人担心,辅助使用异体血浆可能会对患者的凝血和炎症状态造成有害干扰。我们假设,相对于热损伤后的基线,血浆包容性复苏(PIR)不会引起血栓形成前的变化:方法:研究人员招募了地区烧伤中心收治的患者,这些患者在烧伤复苏过程中接受了 PIR 治疗。通过快速血栓弹性成像和旋转血栓弹性测定法对全血样本进行前瞻性分析,以评估急性烧伤复苏期间四个时间点的凝血病变。采用重复测量的混合效应模型和 Tukey's 事后比较试验来检验组间差异:结果:共有 35 名患者参与分析。大多数患者为男性(74.3%),中位年龄为 43 岁(32-55 岁),28.6%的患者同时伴有吸入性损伤,体表总面积烧伤率为 34%(27%-48.5%),总体死亡率为 28.6%。没有发生输血反应或血栓事件。血栓弹力图或旋转血栓弹力测定的参数总体上没有差异,按死亡率、总体表面积烧伤和吸入性损伤分层时也没有差异。随着时间的推移,纤溶表型之间也没有明显差异:数据表明,与基线相比,PIR 与烧伤患者的血栓形成或溶解变化无关。需要进一步研究来证实这些发现,并评估 PIR 在急性烧伤复苏中的疗效。
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引用次数: 0
Blood Clots Used as Natural Biomaterials for Antibiotic Delivery in Vitro 将血凝块用作体外输送抗生素的天然生物材料
IF 1.8 3区 医学 Q2 SURGERY Pub Date : 2024-10-07 DOI: 10.1016/j.jss.2024.09.018
Jennifer C. Ku BA , Haiying Pan MS , Genevieve M. Abd PhD , David M. Richter BS , Ashley Minor BS , Robert G. Sawyer MD , Yong Li MD, PhD

Introduction

The search for an optimal drug delivery system capable of addressing a wide range of wounds and defects in regenerative medicine remains a challenge. Blood clots (BCs) have been implicated as a promising candidate due to their natural occurrence, autologous nature, and potential for tissue repair. The aim of this study is to investigate BC as a vehicle for antibiotic delivery and its effectiveness in infection control.

Methods

BCs derived from murine and porcine models were used to study the in vitro release of gentamicin and vancomycin over a 7-d period. Moreover, BCs conjugated with mesenchymal stem cells and these antibiotics were assessed for antimicrobial activity via microdilution and agar well diffusion, and quantification of vascular endothelial growth factor release through enzyme-linked immunosorbent assay.

Results

Conjugated BCs maintained a sustained release of gentamicin and vancomycin throughout the 7-d period. Functional tests confirmed antimicrobial activity with zones of inhibition comparable to antibiotic controls. Vascular endothelial growth factor quantification revealed a pronounced and sustained release, especially from BCs conjugated with male mesenchymal stem cells, suggesting a gender influence on therapeutic outcomes. This sex-specific variance underscores the need for tailored therapeutic approaches in regenerative medicine applications.

Conclusions

We demonstrated the remarkable potential of BC as a drug delivery system through sustained antibiotic and growth factor release, both of which are key in preventing infection and promoting tissue regeneration. The ease and cost effectiveness of BC preparation as well as its favorable federal regulatory profile support the potential translational application of BCs as a natural biomaterial in regenerative medicine.
导言:在再生医学领域,寻找一种能够治疗各种创伤和缺陷的最佳给药系统仍然是一项挑战。血凝块(BC)因其天然存在、自体性质和组织修复潜力而被认为是一种有前途的候选材料。本研究旨在探讨血凝块作为抗生素输送载体及其在感染控制中的有效性:方法:研究人员利用从鼠和猪模型中提取的碱性纤维素研究了庆大霉素和万古霉素在体外 7 天的释放情况。此外,还通过微量稀释法和琼脂井扩散法评估了与间充质干细胞和这些抗生素共轭的碱性细胞的抗菌活性,并通过酶联免疫吸附试验量化了血管内皮生长因子的释放量:结果:共轭 BCs 在 7 天的时间内保持了庆大霉素和万古霉素的持续释放。功能测试证实了其抗菌活性,抑制区与抗生素对照组相当。血管内皮生长因子定量分析显示,特别是与雄性间充质干细胞结合的生物活性成分能明显、持续地释放血管内皮生长因子,这表明性别对治疗效果有影响。这种性别特异性差异强调了再生医学应用中定制治疗方法的必要性:我们通过持续释放抗生素和生长因子证明了碱性生物碱作为药物输送系统的巨大潜力,这两种物质都是预防感染和促进组织再生的关键。制备碱性纤维素的简易性和成本效益以及其良好的联邦监管形象支持了碱性纤维素作为天然生物材料在再生医学中的潜在转化应用。
{"title":"Blood Clots Used as Natural Biomaterials for Antibiotic Delivery in Vitro","authors":"Jennifer C. Ku BA ,&nbsp;Haiying Pan MS ,&nbsp;Genevieve M. Abd PhD ,&nbsp;David M. Richter BS ,&nbsp;Ashley Minor BS ,&nbsp;Robert G. Sawyer MD ,&nbsp;Yong Li MD, PhD","doi":"10.1016/j.jss.2024.09.018","DOIUrl":"10.1016/j.jss.2024.09.018","url":null,"abstract":"<div><h3>Introduction</h3><div>The search for an optimal drug delivery system capable of addressing a wide range of wounds and defects in regenerative medicine remains a challenge. Blood clots (BCs) have been implicated as a promising candidate due to their natural occurrence, autologous nature, and potential for tissue repair. The aim of this study is to investigate BC as a vehicle for antibiotic delivery and its effectiveness in infection control.</div></div><div><h3>Methods</h3><div>BCs derived from murine and porcine models were used to study the <em>in vitro</em> release of gentamicin and vancomycin over a 7-d period. Moreover, BCs conjugated with mesenchymal stem cells and these antibiotics were assessed for antimicrobial activity via microdilution and agar well diffusion, and quantification of vascular endothelial growth factor release through enzyme-linked immunosorbent assay.</div></div><div><h3>Results</h3><div>Conjugated BCs maintained a sustained release of gentamicin and vancomycin throughout the 7-d period. Functional tests confirmed antimicrobial activity with zones of inhibition comparable to antibiotic controls. Vascular endothelial growth factor quantification revealed a pronounced and sustained release, especially from BCs conjugated with male mesenchymal stem cells, suggesting a gender influence on therapeutic outcomes. This sex-specific variance underscores the need for tailored therapeutic approaches in regenerative medicine applications.</div></div><div><h3>Conclusions</h3><div>We demonstrated the remarkable potential of BC as a drug delivery system through sustained antibiotic and growth factor release, both of which are key in preventing infection and promoting tissue regeneration. The ease and cost effectiveness of BC preparation as well as its favorable federal regulatory profile support the potential translational application of BCs as a natural biomaterial in regenerative medicine.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative Communication Among Men and Women Surgeons With Nursing and Anesthesia Providers. 男女外科医生与护理和麻醉人员的术中交流。
IF 1.8 3区 医学 Q2 SURGERY Pub Date : 2024-10-07 DOI: 10.1016/j.jss.2024.07.129
Deanna Plewa, Caroline Ricard, Diana Hockett, Dena Shehata, Abigail Corrington, Tasneem Zaihra Rizvi, Zhibang Lin, Manuel Castillo-Angeles, Elizabeth Preston, Luke Dong, Dmitry Nepomnayshy, Ammara Watkins

Introduction: Gender bias has been reported by women surgeons, but its impact on communication in the operating room (OR) is unclear. OR communication is critical to understand, as it directly impacts patient outcomes. The current study evaluates potential gender bias in the type and quality of communication between surgeons and OR nursing and anesthesia providers.

Methods: We developed a novel intraoperative communication assessment tool, Operating Room Communication Quality assessment tool (OComm), which was adapted from previously validated teamwork assessment tools. Independent coders recorded the instances of conversation and categorized them into clinical or casual communication. After the operation, the participants were assigned a score from the OComm tool. Participants were then given the same OComm measure to assess their self-perceived communication quality and collect demographic information.

Results: For both genders, surgeons' median self-perceived OComm scores was 3.47/4, but surgeons observed OComm score was 2.91/4. Anesthesia providers noted the highest median self-perceived OComm score of 3.65/4 but the lowest observed OComm median score of 2.29/4. From both surgeon to nurse and surgeon to anesthesia provider, there was no association between the gender and frequency of casual conversation (P = 1 > 0.025).

Conclusions: There was no gender difference in the degree to which women and men surgeons engaged in casual conversation with nursing and anesthesia providers. Surgeons, both men and women, were also more likely to rate their quality of communication lower than the nurses and anesthesia providers, while independent coders were more likely to rate surgeons' quality of communication higher than that of nurses and anesthesia providers.

导言:女外科医生曾报告过性别偏见,但其对手术室(OR)沟通的影响尚不清楚。手术室沟通直接影响患者的治疗效果,因此了解手术室沟通至关重要。本研究评估了外科医生与手术室护理和麻醉提供者之间在沟通类型和质量方面可能存在的性别偏见:我们开发了一种新颖的术中交流评估工具--手术室交流质量评估工具(OComm),该工具改编自之前经过验证的团队合作评估工具。独立编码员记录谈话内容,并将其分为临床沟通和休闲沟通。手术结束后,根据 OComm 工具对参与者进行评分。然后,参与者接受相同的 OComm 测量,以评估他们自我感觉的沟通质量,并收集人口统计学信息:男女外科医生的自我感觉 OComm 得分中位数均为 3.47/4,但外科医生的观察 OComm 得分为 2.91/4。麻醉提供者的自我感觉 OComm 得分中位数最高,为 3.65/4,但观察到的 OComm 得分中位数最低,为 2.29/4。无论是从外科医生到护士还是从外科医生到麻醉提供者,性别与随意交谈的频率之间没有关联(P = 1 > 0.025):结论:男女外科医生与护理人员和麻醉提供者进行随意交谈的程度没有性别差异。外科医生(包括男性和女性)对其交流质量的评价也更有可能低于护士和麻醉提供者,而独立编码员对外科医生交流质量的评价则更有可能高于护士和麻醉提供者。
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引用次数: 0
Response to the Letter to the Editor: Physicians are Unable to Consistently Predict Patient Health Literacy in a Breast Clinic. 回应致编辑的信:医生无法一致预测乳腺门诊中患者的健康素养。
IF 1.8 3区 医学 Q2 SURGERY Pub Date : 2024-10-06 DOI: 10.1016/j.jss.2024.08.024
Lena M Turkheimer, Shayna L Showalter
{"title":"Response to the Letter to the Editor: Physicians are Unable to Consistently Predict Patient Health Literacy in a Breast Clinic.","authors":"Lena M Turkheimer, Shayna L Showalter","doi":"10.1016/j.jss.2024.08.024","DOIUrl":"https://doi.org/10.1016/j.jss.2024.08.024","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter Regarding: "Digital Ink and Surgical Dreams: Perceptions of Artificial Intelligence-Generated Essays in Residency Applications". 关于"数字墨水与外科梦想:对人工智能生成的住院实习申请论文的看法"。
IF 1.8 3区 医学 Q2 SURGERY Pub Date : 2024-10-06 DOI: 10.1016/j.jss.2024.08.025
Shigeki Matsubara, Daisuke Matsubara
{"title":"Letter Regarding: \"Digital Ink and Surgical Dreams: Perceptions of Artificial Intelligence-Generated Essays in Residency Applications\".","authors":"Shigeki Matsubara, Daisuke Matsubara","doi":"10.1016/j.jss.2024.08.025","DOIUrl":"https://doi.org/10.1016/j.jss.2024.08.025","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter Regarding: Tactical Indications of Cricothyroidotomy in Combat-Setting. 关于:在战斗环境中进行环甲膜切开术的战术适应症。
IF 1.8 3区 医学 Q2 SURGERY Pub Date : 2024-10-05 DOI: 10.1016/j.jss.2024.07.128
Audrey Jarrassier, Arwad Alkahwaji, Jean-Baptiste Morvan, Pierre Pasquier
{"title":"Letter Regarding: Tactical Indications of Cricothyroidotomy in Combat-Setting.","authors":"Audrey Jarrassier, Arwad Alkahwaji, Jean-Baptiste Morvan, Pierre Pasquier","doi":"10.1016/j.jss.2024.07.128","DOIUrl":"https://doi.org/10.1016/j.jss.2024.07.128","url":null,"abstract":"","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of Pediatric Surgical Infrastructure With Clinical and Economic Outcomes: A Cohort Study 小儿外科基础设施与临床和经济结果的相关性:队列研究。
IF 1.8 3区 医学 Q2 SURGERY Pub Date : 2024-10-05 DOI: 10.1016/j.jss.2024.09.006
Samuel Negash MD , Ava Yap MD, MHS , Caroline Q. Stephens MD, MPH , Beimnet Girma Nigussie MD , Ruth Fekadu Tefera MD , Emma Bryce MPH , Maija Cheung MD , Maira Fedatto PhD , Ruth Laverde BS , Doruk Ozgediz MD, MSc , Amezene Tadesse MD , Miliard Derbew MD

Introduction

A significant burden of unmet pediatric surgical disease exists in low- and middle-income countries. We sought to assess the associations between the installation of a pediatric operating room (OR) and clinical and economic outcomes for families with children in Ethiopia.

Methods

A retrospective cohort study was performed of children who underwent elective surgery in a tertiary-level Ethiopian public hospital, comparing patient outcomes before and after OR installation in August 2019. Clinical data were collected via chart review, and an inpatient economic survey was administered to patient caregivers. Interrupted time series analysis investigated trends in surgical volume over time. The relative economic benefit was determined by comparing the patients’ household income to the monetary health benefit gained using the value of statistical life method.

Results

One thousand one hundred and ninety-six patients were included from August 2018 to July 2022. Surgery averted 20,541 disability-adjusted life years (DALYs) cumulatively or 17 DALYs per patient. Monthly case volume and DALYs averted significantly increased postinstallation. The median annual household income of the economic survey responders (n = 339) was $1337 (IQR 669-2592). 27.7% (n = 94/339) lived in extreme poverty, and 41.3% (n = 140/339) experienced catastrophic healthcare expenditure. Net monetary health benefit was $29.3 million or $26,646 per patient. The ratio of net monetary health benefit to household annual income was 60:1.

Conclusions

Installing a pediatric OR in a public Ethiopian hospital ensures increased access to surgery for those most impoverished in Ethiopia and improves equitable access to surgical care. Greater investment in expanding pediatric surgical infrastructure can help address global inequities in child health.
导言:在低收入和中等收入国家,儿科外科疾病的发病率居高不下。我们试图评估儿科手术室的设置与埃塞俄比亚儿童家庭的临床和经济效益之间的关系:我们对在埃塞俄比亚一家三级公立医院接受择期手术的儿童进行了一项回顾性队列研究,比较了 2019 年 8 月手术室安装前后的患者治疗效果。临床数据通过病历审查收集,住院病人经济调查由病人护理人员进行。中断时间序列分析调查了手术量随时间变化的趋势。使用统计生命值法比较了患者的家庭收入和获得的货币健康效益,从而确定了相对经济效益:从2018年8月至2022年7月,共纳入了1196名患者。手术累计避免了 20541 个残疾调整寿命年(DALYs),即每位患者避免了 17 个残疾调整寿命年。安装后,每月的病例量和避免的残疾调整寿命年数显著增加。经济调查应答者(n = 339)的家庭年收入中位数为 1337 美元(IQR 为 669-2592 美元)。27.7%(n = 94/339)的人生活极端贫困,41.3%(n = 140/339)的人经历过灾难性医疗支出。每位患者的健康净收益为 2,930 万美元,即 26,646 美元。医疗净收益与家庭年收入之比为 60:1.结论:在埃塞俄比亚的一家公立医院安装儿科手术室可确保埃塞俄比亚最贫困的人群获得更多的手术机会,并改善手术护理的公平性。加大投资,扩大儿科手术基础设施,有助于解决全球儿童健康不平等的问题。
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引用次数: 0
Medical Alert Cards for Pediatric Patients With Antegrade Continence Enemas to Enhance Awareness 为使用逆行性失禁灌肠器的儿科患者制作医疗警示卡,以提高认知度。
IF 1.8 3区 医学 Q2 SURGERY Pub Date : 2024-10-05 DOI: 10.1016/j.jss.2024.09.020
Elizaveta Bokova MD , Ninad Prasade BS , Ismael Elhalaby MD , Margaret Martin-McLain MSN, RN, CPN , Wendy E. Lewis RN, NP , Christine N. Feira NP , Irene Isabel P. Lim MD, MPH , Rebecca M. Rentea MD, MS, MBA

Introduction

The antegrade continence enema (ACE) is a surgical technique that establishes a route for colonic irrigation, necessitating a detailed comprehension of the procedural methodology, including the conduit construction, the catheters selection, and the administration of irrigation solutions. It is critical to disseminate comprehensive information regarding ACE procedures to health-care professionals and caregivers to enhance their understanding and support management of patients undergoing this intervention. This study aims to evaluate the efficacy of a novel educational tool designed to augment the knowledge base of physicians and caregivers regarding ACE procedures.

Methods

Medical alert cards were conceptualized for patients managed with ACEs via an appendicostomy, neoappendicostomy, or cecostomy. These cards included essential information such as (1) contact details of the health-care team, (2) specifics of the surgical procedure, (3) criteria for emergency department referral, and (4) bespoke patient-specific information. A single-institution survey was conducted to assess the cards’ role in improving awareness of ACE procedures among health-care providers and caregivers and guiding management of patients with ACEs. The study adhered to Consensus-Based Checklist for Reporting of Survey Studies guidelines.

Results

Twenty-seven responses were collected from 18 health-care providers and nine caregivers. A significant majority (n = 24, 88%) affirmed the cards’ effectiveness in providing detailed information about individual patients. The design and layout of the card were well-received by 93% (n = 25) of respondents, with a median readability score of 8 (interquartile range 7-10). Additionally, some providers (n = 3, 17%) highlighted the card’s utility in facilitating patient referrals to specialized care centers. Suggestions for improvement included adding information about different types of tubes, enhancing readability, and optimizing the visual representation of the conduit.

Conclusions

Medical alert cards demonstrated a significant potential to improve understanding of ACEs among health-care providers and caregivers. The cards aid in informing stakeholders about the ACE procedure, guiding the child’s management, and referring the patients to specialized care facilities when necessary.
导言:前行性持续灌肠(ACE)是一种建立结肠灌洗路径的外科技术,需要详细了解手术方法,包括导管结构、导管选择和灌洗溶液的使用。向医护专业人员和护理人员传播有关 ACE 程序的全面信息至关重要,这样可以增强他们对这一干预措施的理解并支持对患者的管理。本研究旨在评估一种新型教育工具的效果,该工具旨在增强医生和护理人员有关 ACE 程序的知识基础:方法:为通过阑尾造口术、新阑尾造口术或盲肠造口术接受 ACE 治疗的患者设计了医疗提示卡。这些卡片包括以下基本信息:(1) 医疗团队的详细联系方式;(2) 手术过程的具体细节;(3) 急诊科转诊标准;(4) 特定患者的定制信息。研究人员对单个机构进行了调查,以评估该卡在提高医疗服务提供者和护理人员对 ACE 手术的认识以及指导 ACE 患者管理方面的作用。该研究遵循了基于共识的调查研究报告核对表指南:从 18 名医疗服务提供者和 9 名护理人员那里收集到 27 份回复。绝大多数人(n = 24,88%)肯定了卡片在提供患者详细信息方面的有效性。93%(n=25)的受访者对卡片的设计和布局表示满意,可读性的中位数为 8 分(四分位间范围为 7-10)。此外,一些医疗服务提供者(n = 3,17%)强调了该卡在促进患者转诊至专业护理中心方面的实用性。改进建议包括增加有关不同类型管道的信息、提高可读性以及优化导管的视觉效果:医疗警报卡在提高医疗服务提供者和护理人员对 ACE 的认识方面具有很大的潜力。医疗提示卡有助于向相关人员介绍 ACE 的治疗过程,指导患儿的治疗,并在必要时将患者转介到专门的护理机构。
{"title":"Medical Alert Cards for Pediatric Patients With Antegrade Continence Enemas to Enhance Awareness","authors":"Elizaveta Bokova MD ,&nbsp;Ninad Prasade BS ,&nbsp;Ismael Elhalaby MD ,&nbsp;Margaret Martin-McLain MSN, RN, CPN ,&nbsp;Wendy E. Lewis RN, NP ,&nbsp;Christine N. Feira NP ,&nbsp;Irene Isabel P. Lim MD, MPH ,&nbsp;Rebecca M. Rentea MD, MS, MBA","doi":"10.1016/j.jss.2024.09.020","DOIUrl":"10.1016/j.jss.2024.09.020","url":null,"abstract":"<div><h3>Introduction</h3><div>The antegrade continence enema (ACE) is a surgical technique that establishes a route for colonic irrigation, necessitating a detailed comprehension of the procedural methodology, including the conduit construction, the catheters selection, and the administration of irrigation solutions. It is critical to disseminate comprehensive information regarding ACE procedures to health-care professionals and caregivers to enhance their understanding and support management of patients undergoing this intervention. This study aims to evaluate the efficacy of a novel educational tool designed to augment the knowledge base of physicians and caregivers regarding ACE procedures.</div></div><div><h3>Methods</h3><div>Medical alert cards were conceptualized for patients managed with ACEs via an appendicostomy, neoappendicostomy, or cecostomy. These cards included essential information such as (1) contact details of the health-care team, (2) specifics of the surgical procedure, (3) criteria for emergency department referral, and (4) bespoke patient-specific information. A single-institution survey was conducted to assess the cards’ role in improving awareness of ACE procedures among health-care providers and caregivers and guiding management of patients with ACEs. The study adhered to Consensus-Based Checklist for Reporting of Survey Studies guidelines.</div></div><div><h3>Results</h3><div>Twenty-seven responses were collected from 18 health-care providers and nine caregivers. A significant majority (<em>n</em> = 24, 88%) affirmed the cards’ effectiveness in providing detailed information about individual patients. The design and layout of the card were well-received by 93% (<em>n</em> = 25) of respondents, with a median readability score of 8 (interquartile range 7-10). Additionally, some providers (<em>n</em> = 3, 17%) highlighted the card’s utility in facilitating patient referrals to specialized care centers. Suggestions for improvement included adding information about different types of tubes, enhancing readability, and optimizing the visual representation of the conduit.</div></div><div><h3>Conclusions</h3><div>Medical alert cards demonstrated a significant potential to improve understanding of ACEs among health-care providers and caregivers. The cards aid in informing stakeholders about the ACE procedure, guiding the child’s management, and referring the patients to specialized care facilities when necessary.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Surgical Research
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