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re: Limitations of the commercially available gene expression test in predicting cutaneous squamous cell carcinoma metastasis and clinical outcomes.
IF 12.8 1区 医学 Q1 DERMATOLOGY Pub Date : 2025-03-15 DOI: 10.1016/j.jaad.2025.02.092
Matthew S Goldberg, Victor Brodsky, Patrick Emanuel
{"title":"re: Limitations of the commercially available gene expression test in predicting cutaneous squamous cell carcinoma metastasis and clinical outcomes.","authors":"Matthew S Goldberg, Victor Brodsky, Patrick Emanuel","doi":"10.1016/j.jaad.2025.02.092","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.092","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Supplemental Nutrition Assistance Program (SNAP) and Cost-Related Medical Care Delays in Pediatric Atopic Dermatitis: A Cross-Sectional Analysis of the National Health Interview Survey, 1999-2018.
IF 12.8 1区 医学 Q1 DERMATOLOGY Pub Date : 2025-03-15 DOI: 10.1016/j.jaad.2025.03.025
Christopher G Youn, Arash Pour Mohammad, Ann L Marqueling, Dawn H Siegel, Justin M Ko, Gordon H Bae
{"title":"Association Between Supplemental Nutrition Assistance Program (SNAP) and Cost-Related Medical Care Delays in Pediatric Atopic Dermatitis: A Cross-Sectional Analysis of the National Health Interview Survey, 1999-2018.","authors":"Christopher G Youn, Arash Pour Mohammad, Ann L Marqueling, Dawn H Siegel, Justin M Ko, Gordon H Bae","doi":"10.1016/j.jaad.2025.03.025","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.025","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ruxolitinib versus Roflumilast: A Meta-analysis of the Comparative Efficacy of Two Topical Therapies for Atopic Dermatitis.
IF 12.8 1区 医学 Q1 DERMATOLOGY Pub Date : 2025-03-14 DOI: 10.1016/j.jaad.2025.03.019
Sana Gupta, Grace Xiong, Christopher Shenouda, Samantha Keow, Mohannad Abu-Hilal
{"title":"Ruxolitinib versus Roflumilast: A Meta-analysis of the Comparative Efficacy of Two Topical Therapies for Atopic Dermatitis.","authors":"Sana Gupta, Grace Xiong, Christopher Shenouda, Samantha Keow, Mohannad Abu-Hilal","doi":"10.1016/j.jaad.2025.03.019","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.019","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Augmented Intelligence and Dermatology - Part I: Core Concepts and Applications. 增强智能与皮肤病学--第一部分:核心概念与应用。
IF 12.8 1区 医学 Q1 DERMATOLOGY Pub Date : 2025-03-14 DOI: 10.1016/j.jaad.2024.09.090
Daniel Schlessinger, Justin Ko, Ivy Lee, Veronica Rotemberg, Roberto Novoa
{"title":"Augmented Intelligence and Dermatology - Part I: Core Concepts and Applications.","authors":"Daniel Schlessinger, Justin Ko, Ivy Lee, Veronica Rotemberg, Roberto Novoa","doi":"10.1016/j.jaad.2024.09.090","DOIUrl":"https://doi.org/10.1016/j.jaad.2024.09.090","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Augmented Intelligence and Dermatology - Part II: Bias, Benchmarks, Guidelines, Ethics, Regulation, and Future Directions.
IF 12.8 1区 医学 Q1 DERMATOLOGY Pub Date : 2025-03-14 DOI: 10.1016/j.jaad.2024.10.132
Edwin Dovigi, Shannon Wongvibulsin, Ivy Lee, Rob Novoa, Zhuo Cai, Veronica Rotemberg, Roxana Daneshjou

Despite the proliferation of artificial intelligence (AI) tools, numerous challenges remain in the development and evaluation of AI related technologies. Furthermore, a practice gap exists in how to responsibly implement AI effectively, ethically, and legally in dermatology. Part 2 of this continuing medical education review series will explain the key technical challenges and principles of trustworthy and responsible AI as well as describe the ethical challenges and review resources to help guide safe, effective, and ethical AI in dermatology. This content will empower learners to critically analyze these tools and determine whether an AI solution is appropriate for their specific clinical need, patient, and practice setting.

{"title":"Augmented Intelligence and Dermatology - Part II: Bias, Benchmarks, Guidelines, Ethics, Regulation, and Future Directions.","authors":"Edwin Dovigi, Shannon Wongvibulsin, Ivy Lee, Rob Novoa, Zhuo Cai, Veronica Rotemberg, Roxana Daneshjou","doi":"10.1016/j.jaad.2024.10.132","DOIUrl":"https://doi.org/10.1016/j.jaad.2024.10.132","url":null,"abstract":"<p><p>Despite the proliferation of artificial intelligence (AI) tools, numerous challenges remain in the development and evaluation of AI related technologies. Furthermore, a practice gap exists in how to responsibly implement AI effectively, ethically, and legally in dermatology. Part 2 of this continuing medical education review series will explain the key technical challenges and principles of trustworthy and responsible AI as well as describe the ethical challenges and review resources to help guide safe, effective, and ethical AI in dermatology. This content will empower learners to critically analyze these tools and determine whether an AI solution is appropriate for their specific clinical need, patient, and practice setting.</p>","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of Tuberculosis Screening in Psoriasis Patients Treated with Biologics and Traditional Immunosuppressant Medications: Experience at a Single U.S. Institution.
IF 12.8 1区 医学 Q1 DERMATOLOGY Pub Date : 2025-03-14 DOI: 10.1016/j.jaad.2025.02.090
Blake Vest, Michael Buhnerkempe, Kenneth Minielly, Rebecca Larson
{"title":"Utility of Tuberculosis Screening in Psoriasis Patients Treated with Biologics and Traditional Immunosuppressant Medications: Experience at a Single U.S. Institution.","authors":"Blake Vest, Michael Buhnerkempe, Kenneth Minielly, Rebecca Larson","doi":"10.1016/j.jaad.2025.02.090","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.090","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reduced Major Adverse Cardiovascular Events (MACE) with Interleukin-17 Inhibitors Compared to Methotrexate in Psoriasis Patients: A multi-center retrospective cohort analysis. 与甲氨蝶呤相比,白细胞介素-17抑制剂可减少银屑病患者的主要心血管不良事件(MACE):多中心回顾性队列分析。
IF 12.8 1区 医学 Q1 DERMATOLOGY Pub Date : 2025-03-13 DOI: 10.1016/j.jaad.2025.03.014
Rahib K Islam, Alexander Maltese, Kazi N Islam, Jashin J Wu
{"title":"Reduced Major Adverse Cardiovascular Events (MACE) with Interleukin-17 Inhibitors Compared to Methotrexate in Psoriasis Patients: A multi-center retrospective cohort analysis.","authors":"Rahib K Islam, Alexander Maltese, Kazi N Islam, Jashin J Wu","doi":"10.1016/j.jaad.2025.03.014","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.014","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retiform purpura.
IF 12.8 1区 医学 Q1 DERMATOLOGY Pub Date : 2025-03-13 DOI: 10.1016/j.jaad.2025.03.017
Fatima Farrukh, Abraham M Korman
{"title":"Retiform purpura.","authors":"Fatima Farrukh, Abraham M Korman","doi":"10.1016/j.jaad.2025.03.017","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.017","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-sectional analysis of mental health comorbidities in patients with prurigo nodularis. 对结节性瘙痒症患者精神健康合并症的横断面分析。
IF 12.8 1区 医学 Q1 DERMATOLOGY Pub Date : 2025-03-13 DOI: 10.1016/j.jaad.2025.03.015
Daniela Frankel, Emily Ma, Davies Gage, Yagiz Matthew Akiska, Shahin Shahsavari, Shawn G Kwatra
{"title":"Cross-sectional analysis of mental health comorbidities in patients with prurigo nodularis.","authors":"Daniela Frankel, Emily Ma, Davies Gage, Yagiz Matthew Akiska, Shahin Shahsavari, Shawn G Kwatra","doi":"10.1016/j.jaad.2025.03.015","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.015","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term Cardiovascular Safety of Ustekinumab in Psoriasis and Psoriatic Arthritis: Results from an Observational Post-Authorization Safety Study Based on Swedish National Registers.
IF 12.8 1区 医学 Q1 DERMATOLOGY Pub Date : 2025-03-13 DOI: 10.1016/j.jaad.2025.03.016
Jonas Banefelt, Helena Skröder, Ahlem Azzabi, Anna Sheahan, Robert Suruki, Anja Geldhof

Background: Evidence on the comparative cardiovascular safety of ustekinumab in psoriasis (PsO) and psoriatic arthritis (PsA) remains limited.

Objective: To assess risk of major adverse cardiovascular events (MACE) among PsO and PsA patients treated with ustekinumab compared to those treated with adalimumab, etanercept, or secukinumab in routine clinical practice.

Methods: This new-user, active-comparator, observational cohort study used patient-level data from Swedish national registers, including adult PsO/PsA patients initiating treatment with ustekinumab or a comparator between 2009-2021, with patients assigned to mutually exclusive cohorts. The primary outcome was incident MACE, defined as myocardial infarction, ischemic stroke, or cardiovascular-related death. Adjusted hazard ratios (HR) were estimated using cause-specific Cox regression with stabilized inverse probability of treatment weighting by propensity scores.

Results: A total of 15,502 patients were included (852 ustekinumab-treated), with 147 MACE observed during follow-up. Adjusted HRs (95% CI) comparing ustekinumab to adalimumab, etanercept, and secukinumab were 1.07 (0.49-2.33), 1.08 (0.48-2.42), and 1.19 (0.46-3.10), respectively.

Limitations: Observational study, drug allocation not randomized, and lack of disease severity data.

Conclusion: This nationwide study of Swedish PsO/PsA patients spanning >10 years found no evidence of different cardiovascular safety profiles of ustekinumab versus adalimumab, etanercept, or secukinumab in real-world clinical practice.

{"title":"Long-term Cardiovascular Safety of Ustekinumab in Psoriasis and Psoriatic Arthritis: Results from an Observational Post-Authorization Safety Study Based on Swedish National Registers.","authors":"Jonas Banefelt, Helena Skröder, Ahlem Azzabi, Anna Sheahan, Robert Suruki, Anja Geldhof","doi":"10.1016/j.jaad.2025.03.016","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.03.016","url":null,"abstract":"<p><strong>Background: </strong>Evidence on the comparative cardiovascular safety of ustekinumab in psoriasis (PsO) and psoriatic arthritis (PsA) remains limited.</p><p><strong>Objective: </strong>To assess risk of major adverse cardiovascular events (MACE) among PsO and PsA patients treated with ustekinumab compared to those treated with adalimumab, etanercept, or secukinumab in routine clinical practice.</p><p><strong>Methods: </strong>This new-user, active-comparator, observational cohort study used patient-level data from Swedish national registers, including adult PsO/PsA patients initiating treatment with ustekinumab or a comparator between 2009-2021, with patients assigned to mutually exclusive cohorts. The primary outcome was incident MACE, defined as myocardial infarction, ischemic stroke, or cardiovascular-related death. Adjusted hazard ratios (HR) were estimated using cause-specific Cox regression with stabilized inverse probability of treatment weighting by propensity scores.</p><p><strong>Results: </strong>A total of 15,502 patients were included (852 ustekinumab-treated), with 147 MACE observed during follow-up. Adjusted HRs (95% CI) comparing ustekinumab to adalimumab, etanercept, and secukinumab were 1.07 (0.49-2.33), 1.08 (0.48-2.42), and 1.19 (0.46-3.10), respectively.</p><p><strong>Limitations: </strong>Observational study, drug allocation not randomized, and lack of disease severity data.</p><p><strong>Conclusion: </strong>This nationwide study of Swedish PsO/PsA patients spanning >10 years found no evidence of different cardiovascular safety profiles of ustekinumab versus adalimumab, etanercept, or secukinumab in real-world clinical practice.</p>","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of the American Academy of Dermatology
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