Pub Date : 2025-02-08DOI: 10.1016/j.jaad.2025.02.017
Cory Shoshany, Karla L Valdes-Morales, Daniela Frankel, Kiara Corcoran Ruiz, Mara Trifoi, Christopher J Miller, Jeremy R Etzkorn, Jocelyn He, Gui-Shuang Ying, César A Briceño
{"title":"Socioeconomic Disparities in Keratinocyte Carcinomas Treated with Mohs Micrographic Surgery.","authors":"Cory Shoshany, Karla L Valdes-Morales, Daniela Frankel, Kiara Corcoran Ruiz, Mara Trifoi, Christopher J Miller, Jeremy R Etzkorn, Jocelyn He, Gui-Shuang Ying, César A Briceño","doi":"10.1016/j.jaad.2025.02.017","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.017","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-07DOI: 10.1016/j.jaad.2025.02.009
Seo Won Cho, Tarun Sontam, Aaron Chen, Emily E Limmer, Stanislav N Tolkachjov
{"title":"GLP-1 Receptor Agonist Use Is Associated with Increased Rates of Acne Vulgaris Diagnosis In Non-Diabetic Obese Women but Not Men: A Retrospective Cohort Study.","authors":"Seo Won Cho, Tarun Sontam, Aaron Chen, Emily E Limmer, Stanislav N Tolkachjov","doi":"10.1016/j.jaad.2025.02.009","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.009","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-07DOI: 10.1016/j.jaad.2025.02.008
Jinhui Xu, Qingwei Geng, Yong Hu, Zehu Liu, Xiuzu Song
{"title":"A simple surgical dressing change for patients with extensive skin exposure.","authors":"Jinhui Xu, Qingwei Geng, Yong Hu, Zehu Liu, Xiuzu Song","doi":"10.1016/j.jaad.2025.02.008","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.008","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-07DOI: 10.1016/j.jaad.2025.02.010
Amit Singal, Shari R Lipner
{"title":"Topical Corticosteroid Exposure is Not Associated with Increased Risk of Pregnancy Complications in a Large Population-based Cohort Study of Psoriasis Patients.","authors":"Amit Singal, Shari R Lipner","doi":"10.1016/j.jaad.2025.02.010","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.010","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-06DOI: 10.1016/j.jaad.2025.02.007
Isabel Arana, Grant J Riew, Adam Rock, Vinod E Nambudiri, Badri Modi, Connie R Shi
{"title":"Cutaneous toxicities associated with epidermal growth factor receptor (EGFR) and mesenchymal epithelial transition factor (MET) dual blockade via bispecific antibody amivantamab.","authors":"Isabel Arana, Grant J Riew, Adam Rock, Vinod E Nambudiri, Badri Modi, Connie R Shi","doi":"10.1016/j.jaad.2025.02.007","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.007","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-06DOI: 10.1016/j.jaad.2025.02.001
Caroline Mann, Andreas Wollenberg, Sascha Ständer, Petra Staubach, Diamant Thaçi, Henner Zirpel
Background: Inflammatory skin diseases such as atopic dermatitis (AD), psoriasis and urticaria are associated with impaired mental health and sleep. In children the risk of developing these comorbidities is still poorly evaluated.
Methods: Retrospective data analysis of a US Collaborative Network including children of 55 Health care providers was performed. Data from electronic health records of patients with a diagnosis of either AD, psoriasis, or urticaria, as well as a control cohort were retrieved in an anonymized batch format and propensity score matched.
Results: Children with psoriasis had a 3.2-fold higher risk for hypersomnia, 2.1-fold higher for sleep apnea, 1.8-fold higher for fatigue and 1.9-fold higher for depression. Children with urticaria (acute or chronic) and AD had a 1.7-fold higher risk for sleep disorders, 1.6 higher for anxiety disorders and 1.4-fold higher for insomnia. AD children had a 1.5-fold higher risk for anxiety disorders.
Limitations: Electronic health insurance data are not subject to random sampling of the general population and potential misdiagnosis is possible.
Conclusion: Children with inflammatory skin diseases were at a higher risk for sleep psychological disorders. Thus, regularly performed screenings and appropriate treatment initiation might potentially prevent mental and physical health consequences and secure improved life quality.
{"title":"Risk of developing sleep disorders and psychologic comorbidity in children with inflammatory skin diseases - a population-based study.","authors":"Caroline Mann, Andreas Wollenberg, Sascha Ständer, Petra Staubach, Diamant Thaçi, Henner Zirpel","doi":"10.1016/j.jaad.2025.02.001","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.001","url":null,"abstract":"<p><strong>Background: </strong>Inflammatory skin diseases such as atopic dermatitis (AD), psoriasis and urticaria are associated with impaired mental health and sleep. In children the risk of developing these comorbidities is still poorly evaluated.</p><p><strong>Methods: </strong>Retrospective data analysis of a US Collaborative Network including children of 55 Health care providers was performed. Data from electronic health records of patients with a diagnosis of either AD, psoriasis, or urticaria, as well as a control cohort were retrieved in an anonymized batch format and propensity score matched.</p><p><strong>Results: </strong>Children with psoriasis had a 3.2-fold higher risk for hypersomnia, 2.1-fold higher for sleep apnea, 1.8-fold higher for fatigue and 1.9-fold higher for depression. Children with urticaria (acute or chronic) and AD had a 1.7-fold higher risk for sleep disorders, 1.6 higher for anxiety disorders and 1.4-fold higher for insomnia. AD children had a 1.5-fold higher risk for anxiety disorders.</p><p><strong>Limitations: </strong>Electronic health insurance data are not subject to random sampling of the general population and potential misdiagnosis is possible.</p><p><strong>Conclusion: </strong>Children with inflammatory skin diseases were at a higher risk for sleep psychological disorders. Thus, regularly performed screenings and appropriate treatment initiation might potentially prevent mental and physical health consequences and secure improved life quality.</p>","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-05DOI: 10.1016/j.jaad.2025.02.005
Frederick T Gibson, Nina A Ran, Ann W Silk, Emily S Ruiz
{"title":"Association of cutaneous immune-related adverse events with improved overall survival among patients with cutaneous squamous cell carcinoma treated with palliative PD-1 inhibition.","authors":"Frederick T Gibson, Nina A Ran, Ann W Silk, Emily S Ruiz","doi":"10.1016/j.jaad.2025.02.005","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.005","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-05DOI: 10.1016/j.jaad.2025.02.004
Frederick T Gibson, Nina A Ran, Chrysalyne D Schmults, Emily S Ruiz
{"title":"Risk of metastasis at presentation and disease-specific death for desmoplastic and spindle cell melanoma: a SEER database analysis.","authors":"Frederick T Gibson, Nina A Ran, Chrysalyne D Schmults, Emily S Ruiz","doi":"10.1016/j.jaad.2025.02.004","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.004","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-05DOI: 10.1016/j.jaad.2025.02.002
Tyan Shin Lee, Mara O'Connor, Leslie Castelo-Soccio, Dawn Eichenfield, Danny Lee, Amy S Paller, Manuel Valdebran, Jenna Vroman, Angela Yang, Grace L Lee, Megan Craddock, Cathryn Sibbald
Background: Androgenetic alopecia (AGA) is a nonscarring alopecia with increasing prevalence in pediatric populations. Published data in pediatrics is limited.
Objective: To perform a multi-center review of pediatric patients with AGA to study clinical presentation, comorbidities, and treatment recommendations.
Methods: A retrospective review of patients presenting with AGA at age <18 years with adequate documentation for data extraction.
Results: In total, 203 patients were included. The mean age of AGA onset was 12.9 ± 2.7 years, and at diagnosis was 14.5 ± 2.1 years. Prepubertal onset occurred in 17 patients, 70.6% female. The majority had a family history of AGA. Of 145 patients with anthropometric data, 24.1% were obese (>95th percentile) and 24.8% overweight (85-95th percentile). Treatments at diagnosis included topical minoxidil in 76.5% and systemic minoxidil in 2.9%, spironolactone in 5.7% of females, and 5-alpha reductase inhibitors in 1.7% of males. Side effects were rare.
Limitations: Data was limited to recorded information.
Conclusion: AGA can occur in prepubertal patients. Potential risk factors for pediatric AGA include obesity and family history. Minoxidil has clinical benefit and is well tolerated in this population. Further prospective studies are recommended to confirm these findings and gather more evidence for treatments.
{"title":"An International Multicenter, Retrospective Cohort Study of 203 Patients with Pediatric Androgenetic Alopecia.","authors":"Tyan Shin Lee, Mara O'Connor, Leslie Castelo-Soccio, Dawn Eichenfield, Danny Lee, Amy S Paller, Manuel Valdebran, Jenna Vroman, Angela Yang, Grace L Lee, Megan Craddock, Cathryn Sibbald","doi":"10.1016/j.jaad.2025.02.002","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.002","url":null,"abstract":"<p><strong>Background: </strong>Androgenetic alopecia (AGA) is a nonscarring alopecia with increasing prevalence in pediatric populations. Published data in pediatrics is limited.</p><p><strong>Objective: </strong>To perform a multi-center review of pediatric patients with AGA to study clinical presentation, comorbidities, and treatment recommendations.</p><p><strong>Methods: </strong>A retrospective review of patients presenting with AGA at age <18 years with adequate documentation for data extraction.</p><p><strong>Results: </strong>In total, 203 patients were included. The mean age of AGA onset was 12.9 ± 2.7 years, and at diagnosis was 14.5 ± 2.1 years. Prepubertal onset occurred in 17 patients, 70.6% female. The majority had a family history of AGA. Of 145 patients with anthropometric data, 24.1% were obese (>95<sup>th</sup> percentile) and 24.8% overweight (85-95<sup>th</sup> percentile). Treatments at diagnosis included topical minoxidil in 76.5% and systemic minoxidil in 2.9%, spironolactone in 5.7% of females, and 5-alpha reductase inhibitors in 1.7% of males. Side effects were rare.</p><p><strong>Limitations: </strong>Data was limited to recorded information.</p><p><strong>Conclusion: </strong>AGA can occur in prepubertal patients. Potential risk factors for pediatric AGA include obesity and family history. Minoxidil has clinical benefit and is well tolerated in this population. Further prospective studies are recommended to confirm these findings and gather more evidence for treatments.</p>","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-05DOI: 10.1016/j.jaad.2025.02.003
Erin Hurd
{"title":"\"'Plumage Sign' helps clinician easily identify pigmented squamous cell carcinoma in situ.\"","authors":"Erin Hurd","doi":"10.1016/j.jaad.2025.02.003","DOIUrl":"https://doi.org/10.1016/j.jaad.2025.02.003","url":null,"abstract":"","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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