Pub Date : 2021-01-30DOI: 10.31254/jsir.2021.10105
O. S
Lemon balm (Lamiaceae) vegetable is known for its aromatherapeutic properties is being used in curring many diseases. The aim of this study was to scientifically screen the medicinally active secondary metabolites and antibacterial potency of Lemon balm vegetable grown in Nigeria. Gas chromatography-mass spectrometry (GCMS) was used to analyse the extract while the antibacterial screening was carried out using agar-well diffusion method. Thirty-four (34) therapeutically active organic compounds were identified in the root extract with terpenoids and phenolic compounds representing the major class, including 2,3-bis[(9E)-9- octadecenoyloxy]propyl (9E)-9-octadecenoate (24.6%) as the major component, methyl (11E)-11-octadecenoate (11.7%), dipalmitin (10.7%), α-methyl-D-galactopyranoside (7.7%), eudesm-7(11)-en-4-ol (4.4%), 1,7,7- trimethylbicyclo[2.2.1]heptan-2-ol (3.0%), isoborneol (2.9%) and 2,6-cresotaldehyde (2.7%) as well as other minor compounds. The highest inhibitory effect of the root extract was observed against Proteus mirabilis which showed a zone of inhibition of 19 mm. The result evidently showed that the sample have several therapeutically active secondary metabolites that can be applied in the treating bacteria diseases.
柠檬香蜂草(Lamiaceae)蔬菜以其芳香治疗特性而闻名，被用于治疗许多疾病。本研究的目的是科学筛选在尼日利亚种植的柠檬香蜂属蔬菜的药用活性次生代谢物和抗菌效力。采用气相色谱-质谱法(GCMS)对提取物进行分析，并用琼脂孔扩散法进行抗菌筛选。从根提取物中鉴定出34种具有治疗活性的有机化合物，其中萜类和酚类化合物为主要成分，包括2,3-二[(9E)-9-十八烯氧基]丙基(9E)-9-十八烯酸酯(24.6%)、甲基(11E)-11-十八烯酸酯(11.7%)、双棕榈素(10.7%)、α-甲基- d -半乳酰基苷(7.7%)、丁香-7(11)-烯-4-醇(4.4%)、1,7,7-三甲基双环[2.2.1]庚烷-2-醇(3.0%)、异龙脑(2.9%)和2,6-甲酚(2.7%)以及其他少量化合物。根提取物对变形杆菌的抑制作用最大，抑制区为19 mm。结果表明，该样品具有几种具有治疗活性的次生代谢物，可应用于细菌性疾病的治疗。
{"title":"Evaluation of Secondary Metabolites and Antibacterial Potency of the Root Extract of Lemon balm (Lamiaceae) Vegetable against Multidrug Resistant Bacteria","authors":"O. S","doi":"10.31254/jsir.2021.10105","DOIUrl":"https://doi.org/10.31254/jsir.2021.10105","url":null,"abstract":"Lemon balm (Lamiaceae) vegetable is known for its aromatherapeutic properties is being used in curring many diseases. The aim of this study was to scientifically screen the medicinally active secondary metabolites and antibacterial potency of Lemon balm vegetable grown in Nigeria. Gas chromatography-mass spectrometry (GCMS) was used to analyse the extract while the antibacterial screening was carried out using agar-well diffusion method. Thirty-four (34) therapeutically active organic compounds were identified in the root extract with terpenoids and phenolic compounds representing the major class, including 2,3-bis[(9E)-9- octadecenoyloxy]propyl (9E)-9-octadecenoate (24.6%) as the major component, methyl (11E)-11-octadecenoate (11.7%), dipalmitin (10.7%), α-methyl-D-galactopyranoside (7.7%), eudesm-7(11)-en-4-ol (4.4%), 1,7,7- trimethylbicyclo[2.2.1]heptan-2-ol (3.0%), isoborneol (2.9%) and 2,6-cresotaldehyde (2.7%) as well as other minor compounds. The highest inhibitory effect of the root extract was observed against Proteus mirabilis which showed a zone of inhibition of 19 mm. The result evidently showed that the sample have several therapeutically active secondary metabolites that can be applied in the treating bacteria diseases.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83176275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-30DOI: 10.31254/jsir.2021.10101
K. Oo, K. M. Lwin, Aye Aye Khai
Roses are the most important cut flowers in the world. Tissue culture of rose has been improved since last twenty years, and exploited for various purposes from basic anatomical and physiological research to micropropagation from auxiliary buds, shoot tips, leaf explants, etc. Single bud nodal stem segments were surface sterilized and then cultured on MS medium supplemented with 30 g/l sugar, 6 g/l agar and different concentrations of BAP(1, 2, 3, 4 and 5mg/l). Among them, the most suitable concentration for shoot initiation and multiplication was 3mg/l BAP. And it also found that the best for shoot elongation occurred in MS medium supplemented with BAP 3 mg/l and GA3 1mg/l. The proliferated microshoots were transferred to root inducing media of half strength MS medium supplemented with 15 g/l sugar, 5 g/l agar and NAA (0.5, 1, 1.5, 2 mg/l). The best rooting was observed at NAA 1 mg/l concentration. The least response in root formation was found at NAA 0.5 mg/l supplementation on half strength MS media.
{"title":"In Vitro Micropropagation of Rose (Hybrid Rosa spp.) through Plant Tissue Culture Technique","authors":"K. Oo, K. M. Lwin, Aye Aye Khai","doi":"10.31254/jsir.2021.10101","DOIUrl":"https://doi.org/10.31254/jsir.2021.10101","url":null,"abstract":"Roses are the most important cut flowers in the world. Tissue culture of rose has been improved since last twenty years, and exploited for various purposes from basic anatomical and physiological research to micropropagation from auxiliary buds, shoot tips, leaf explants, etc. Single bud nodal stem segments were surface sterilized and then cultured on MS medium supplemented with 30 g/l sugar, 6 g/l agar and different concentrations of BAP(1, 2, 3, 4 and 5mg/l). Among them, the most suitable concentration for shoot initiation and multiplication was 3mg/l BAP. And it also found that the best for shoot elongation occurred in MS medium supplemented with BAP 3 mg/l and GA3 1mg/l. The proliferated microshoots were transferred to root inducing media of half strength MS medium supplemented with 15 g/l sugar, 5 g/l agar and NAA (0.5, 1, 1.5, 2 mg/l). The best rooting was observed at NAA 1 mg/l concentration. The least response in root formation was found at NAA 0.5 mg/l supplementation on half strength MS media.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73752517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-30DOI: 10.31254/jsir.2021.10102
T. M. Lynn, Tin Mar Htwe, S. Yu, E. P. Kyaw, Z. K. Latt
Phosphorus (P) limitation in acidic tropical paddy soils is thought to be contributed by the affinity of iron oxides and hydroxides for phosphorus. However, the addition of labile carbon (C) compounds appears to be stimulated iron (Fe) reduction which can release occluded P through Fe cycling. The aim of this study was to investigate the phosphorous mobilization triggered by labile C coupled to iron (Fe) cycling during flooding anaerobic conditions in two P limited paddy soils. Two concentrations (low and high) of equal mixture of glucose and oxalate were added to soil microcosms and they were incubated for one month under flooded condition. During the 30-day experiment, replicate microcosms were destructively harvested for five times and measured total Fe, Fe II, available P and pH. It was found that labile C addition significantly increased total Fe and Fe II in soil solution at early incubation period although the changes were not significant in soil. Available P in soil was not increased and steady throughout the incubation period because the added labile C may not be enough to enhance the P solubilization or available P was dissolved in soil water which we did not measure in this experiment. High amount of labile C addition significantly decreased pH at the start of incubation. pH and available P are negatively correlated at day 7 which is compatible with decreased pH can increase available P. Our results suggest that reducing conditions coupled with labile carbon inputs can stimulate iron reduction and corresponding decreased pH which can triggered soil phosphorus mobilization in P limited paddy soils.
{"title":"Effect of labile carbon on iron reduction and phosphorus availability in two paddy soils","authors":"T. M. Lynn, Tin Mar Htwe, S. Yu, E. P. Kyaw, Z. K. Latt","doi":"10.31254/jsir.2021.10102","DOIUrl":"https://doi.org/10.31254/jsir.2021.10102","url":null,"abstract":"Phosphorus (P) limitation in acidic tropical paddy soils is thought to be contributed by the affinity of iron oxides and hydroxides for phosphorus. However, the addition of labile carbon (C) compounds appears to be stimulated iron (Fe) reduction which can release occluded P through Fe cycling. The aim of this study was to investigate the phosphorous mobilization triggered by labile C coupled to iron (Fe) cycling during flooding anaerobic conditions in two P limited paddy soils. Two concentrations (low and high) of equal mixture of glucose and oxalate were added to soil microcosms and they were incubated for one month under flooded condition. During the 30-day experiment, replicate microcosms were destructively harvested for five times and measured total Fe, Fe II, available P and pH. It was found that labile C addition significantly increased total Fe and Fe II in soil solution at early incubation period although the changes were not significant in soil. Available P in soil was not increased and steady throughout the incubation period because the added labile C may not be enough to enhance the P solubilization or available P was dissolved in soil water which we did not measure in this experiment. High amount of labile C addition significantly decreased pH at the start of incubation. pH and available P are negatively correlated at day 7 which is compatible with decreased pH can increase available P. Our results suggest that reducing conditions coupled with labile carbon inputs can stimulate iron reduction and corresponding decreased pH which can triggered soil phosphorus mobilization in P limited paddy soils.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86419948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. El-Ashrey, Fatma A. Elshibani, Abdullah J. Alamami, Naema Elremali, M. Elderbi
The present study examined some natural active compounds contained in the Libyan Arbutus pavarii Pampan. shrub that might be used as natural inhibitors of SARS-CoV-2, the responsible causative agent of coronavirus disease 2019 (COVID-19). A molecular docking method was employed to find out the capability of the selected molecules to interact with the virus main protease. Seven flavonoids from twenty-seven compounds belonging to different classes showed a remarkable ability to bind to the main protease of the novel coronavirus. The descending order of compounds with the highest binding affinity was as follows: Saponarin, Rutin, Delphinidin3-rutinoside, Neodiosmin, Kampferol-3-O-ß-D-rutinoside, Isoquercetin, and Hyperoside. The outcomes have provided a clear insight into the structure-activity relationship of Mpro targeting agents and may assist the future design of new drug candidates for the disease.
本研究检测了利比亚杨梅中含有的一些天然活性化合物。这种灌木可能被用作2019冠状病毒病(COVID-19)的主要病原体SARS-CoV-2的天然抑制剂。采用分子对接的方法来确定所选分子与病毒主要蛋白酶相互作用的能力。来自27种不同类别化合物的7种黄酮类化合物显示出与新型冠状病毒主要蛋白酶结合的显着能力。结合亲和力最高的化合物由大到小依次为:皂苷、芦丁、飞飞蓟苷-3-芦丁苷、新薯蓣皂苷、Kampferol-3-O-ß- d -芦丁苷、异槲皮素、金丝桃苷。这些结果为Mpro靶向药物的结构-活性关系提供了清晰的见解，并可能有助于未来设计新的候选药物。
{"title":"Prediction of Sars-Cov-2 Main Protease Potential Inhibitors from Libyan Arbutus Pavarii Pampan Compounds: A Molecular Docking Study","authors":"M. El-Ashrey, Fatma A. Elshibani, Abdullah J. Alamami, Naema Elremali, M. Elderbi","doi":"10.31254/jsir.2020.9401","DOIUrl":"https://doi.org/10.31254/jsir.2020.9401","url":null,"abstract":"The present study examined some natural active compounds contained in the Libyan Arbutus pavarii Pampan. shrub that might be used as natural inhibitors of SARS-CoV-2, the responsible causative agent of coronavirus disease 2019 (COVID-19). A molecular docking method was employed to find out the capability of the selected molecules to interact with the virus main protease. Seven flavonoids from twenty-seven compounds belonging to different classes showed a remarkable ability to bind to the main protease of the novel coronavirus. The descending order of compounds with the highest binding affinity was as follows: Saponarin, Rutin, Delphinidin3-rutinoside, Neodiosmin, Kampferol-3-O-ß-D-rutinoside, Isoquercetin, and Hyperoside. The outcomes have provided a clear insight into the structure-activity relationship of Mpro targeting agents and may assist the future design of new drug candidates for the disease.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77392672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. E. Alam, N. Akter, K. Fatema, Md A K Azad, Md. Anwar Arfien Khan, Shimul Chakma
Leather tanning industry, considered one of the polluting industries, poses various environmental threats to its every sphere. It produces various types of solid wastes as well as liquid wastes. Among the solid wastes, untanned raw trimmings contribute for about 5-7% of the total quantity of raw materials processed. If suitably utilized, these by-products of tanning industry could be a useful resource for various applications. This research work deals with utilization of raw trimmings of tannery solid waste to protein hydrolysate by acetic acid with varying acid concentration, acid solution, temperature and time. The maximum about 76% protein hydrolysate was obtained at 1.5M acid concentration and 80ºC.
{"title":"Acid hydrolysis of untanned proteinous wastes from tannery industry in Bangladesh","authors":"M. E. Alam, N. Akter, K. Fatema, Md A K Azad, Md. Anwar Arfien Khan, Shimul Chakma","doi":"10.31254/jsir.2020.9301","DOIUrl":"https://doi.org/10.31254/jsir.2020.9301","url":null,"abstract":"Leather tanning industry, considered one of the polluting industries, poses various environmental threats to its every sphere. It produces various types of solid wastes as well as liquid wastes. Among the solid wastes, untanned raw trimmings contribute for about 5-7% of the total quantity of raw materials processed. If suitably utilized, these by-products of tanning industry could be a useful resource for various applications. This research work deals with utilization of raw trimmings of tannery solid waste to protein hydrolysate by acetic acid with varying acid concentration, acid solution, temperature and time. The maximum about 76% protein hydrolysate was obtained at 1.5M acid concentration and 80ºC.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90381429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ayurveda the classical science of Indian health management mentioned different ways of disease management and utilization of natural drugs is one such way of disease management. These natural drugs offer therapeutic benefits when used alone or in combination. The Ayurveda drugs most of the times gives synergistic effects when used in combination but sometimes gives undesired biological responses therefore it is essential to take consideration of correct combination of herbal medicines to avoid chances of any adverse events. The integration of Ayurveda therapy with Yoga gives better result than any one of them used alone. Similarly, the integration of Ayurveda with modern approaches is prerequisite so that scientific concepts of classical and modern science bring together for managing incurable diseases. The interactions of drugs and integration of therapies can result better therapeutic response but safety concern of such combination is prime issue for medical philosopher.
{"title":"Integrations and Interactions of Ayurveda Drugs: Review W.S.R. to Merits and Demerits","authors":"D. S. Khot, A. Pawar, Sushil Sarjerao Satpute","doi":"10.31254/jsir.2020.9302","DOIUrl":"https://doi.org/10.31254/jsir.2020.9302","url":null,"abstract":"Ayurveda the classical science of Indian health management mentioned different ways of disease management and utilization of natural drugs is one such way of disease management. These natural drugs offer therapeutic benefits when used alone or in combination. The Ayurveda drugs most of the times gives synergistic effects when used in combination but sometimes gives undesired biological responses therefore it is essential to take consideration of correct combination of herbal medicines to avoid chances of any adverse events. The integration of Ayurveda therapy with Yoga gives better result than any one of them used alone. Similarly, the integration of Ayurveda with modern approaches is prerequisite so that scientific concepts of classical and modern science bring together for managing incurable diseases. The interactions of drugs and integration of therapies can result better therapeutic response but safety concern of such combination is prime issue for medical philosopher.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90855700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Detection of Azotobacter species AC9 was done for tolerance of high temperature and analysis of phosphate solubilizing activity, zinc solubilizing activity, hormone production activity and plant growth promoting traits on tomato seedlings. For heat stress tolerance assessment of the isolated strain, our experiment was designed to be suitable for the climate of our country. In this study, Azotobacter chroococcum was isolated from agricultural soil in Kyaukse province and identified by some biochemical characteristics and 16S rRNA sequencing. The isolated strain can tolerate high temperature up to 50 ̊ C. In phosphate solubilizing activity, the strain AC9 showed 183 µg/ml and 166 µg/ml at 5 days incubation period under normal and heat stress conditions respectively. AC9 also expressed highest IAA producing activity at 5 days incubation period for both normal and heat stress conditions. The highest IAA concentrations were 23.72 µg ml-1 (with 0.2% tryptophan), 55.55 µg ml-1 (with 0.5% tryptophan) and 17.73 µg ml-1 (with 0.2% tryptophan), 45.06 µg ml-1 (with 0.5% tryptophan) respectively. Under greenhouse condition, tomato plants inoculated with AC9 grew to a significantly greater extent than control plants.
{"title":"Detection of abiotic stress tolerant Azotobacter species for enhancing plant growth promoting activities","authors":"Ayme Aung, Tin May Sev, A. Mon, S. Yu","doi":"10.31254/jsir.2020.9203","DOIUrl":"https://doi.org/10.31254/jsir.2020.9203","url":null,"abstract":"Detection of Azotobacter species AC9 was done for tolerance of high temperature and analysis of phosphate solubilizing activity, zinc solubilizing activity, hormone production activity and plant growth promoting traits on tomato seedlings. For heat stress tolerance assessment of the isolated strain, our experiment was designed to be suitable for the climate of our country. In this study, Azotobacter chroococcum was isolated from agricultural soil in Kyaukse province and identified by some biochemical characteristics and 16S rRNA sequencing. The isolated strain can tolerate high temperature up to 50 ̊ C. In phosphate solubilizing activity, the strain AC9 showed 183 µg/ml and 166 µg/ml at 5 days incubation period under normal and heat stress conditions respectively. AC9 also expressed highest IAA producing activity at 5 days incubation period for both normal and heat stress conditions. The highest IAA concentrations were 23.72 µg ml-1 (with 0.2% tryptophan), 55.55 µg ml-1 (with 0.5% tryptophan) and 17.73 µg ml-1 (with 0.2% tryptophan), 45.06 µg ml-1 (with 0.5% tryptophan) respectively. Under greenhouse condition, tomato plants inoculated with AC9 grew to a significantly greater extent than control plants.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78237160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Phyllanthus amarus is one of the most important medicinal plant in tropical and subtropical nations which are used for stomach, liver, kidney and spleen diseases treatment. This work involves the elucidation of the phytochemical constituents in 70% ethanolic leaf extract of P. amarus. Phytochemical screening, quantitative and gas chromatography-mass spectrometry (GC-MS) analyses were carried out on the extract. The qualitative and quantitative analyses showed the presence of the following phytochemicals and their contents in mg/100g of extract as phenolic (34.31 ± 0.07), tannin (21.15 ± 0.16), phlobatanin (26.36 ± 0.19), terpernoid (14.71 ± 0.14), steroid (20.37 ± 0.13), cardiac glycoside (20.15 ± 0.19) and alkaloid (23.90±0.05), and absence of flavonoids and saponins. 9,12,15-octadecatrienoic acid, ethyl ester (Z,Z,Z)- (22.47%), Benzenamine, N-[2-(3,4- dimethoxyphenyl)ethyl]-2-nitro- (12.68%), hexadecanoic acid, ethyl ester (12.63%), Beta Tocopherol (12.63%) and phytol (12.61%) were revealed by GC-MS as the major bioactive constituents. The results of this study validated the rich bioactive constituents in P. amarus which may be the reason the plant is being used for the treatment of various ailments.
{"title":"Elucidation of bioactive compounds in hydroalcohol extract of Phyllanthus amarus Schum. and Thonn. leaf using GC-MS analysis","authors":"G. Ajayi, Temitope J Olorunrinu, Muhin A Shittu","doi":"10.31254/jsir.2020.9202","DOIUrl":"https://doi.org/10.31254/jsir.2020.9202","url":null,"abstract":"Phyllanthus amarus is one of the most important medicinal plant in tropical and subtropical nations which are used for stomach, liver, kidney and spleen diseases treatment. This work involves the elucidation of the phytochemical constituents in 70% ethanolic leaf extract of P. amarus. Phytochemical screening, quantitative and gas chromatography-mass spectrometry (GC-MS) analyses were carried out on the extract. The qualitative and quantitative analyses showed the presence of the following phytochemicals and their contents in mg/100g of extract as phenolic (34.31 ± 0.07), tannin (21.15 ± 0.16), phlobatanin (26.36 ± 0.19), terpernoid (14.71 ± 0.14), steroid (20.37 ± 0.13), cardiac glycoside (20.15 ± 0.19) and alkaloid (23.90±0.05), and absence of flavonoids and saponins. 9,12,15-octadecatrienoic acid, ethyl ester (Z,Z,Z)- (22.47%), Benzenamine, N-[2-(3,4- dimethoxyphenyl)ethyl]-2-nitro- (12.68%), hexadecanoic acid, ethyl ester (12.63%), Beta Tocopherol (12.63%) and phytol (12.61%) were revealed by GC-MS as the major bioactive constituents. The results of this study validated the rich bioactive constituents in P. amarus which may be the reason the plant is being used for the treatment of various ailments.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78983117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shaan Tahilramani, Dharmik R Shah, B. Patel, Chirag Vidja, Endrick Contractor
The polystyrene products involved in day to day life serve to its best as per its utility. I t possesses the several properties like Insulation, Light in weight, Cushioning, Non-Reactive Material and Non- Biodegradable. Serving multipurpose it finds wide application in food industry for food packaging, material packaging in the electrical device sector, construction sector etc. There are demerits associated with the product after use i.e. waste product disposal is the major problem incurred curre ntly. It is becoming a part of landfill and increasing the amount of solid waste. It can even harm animals that scavenge food from the landfills. Our project aims to reduce and develop methodologies to treat the polystyrene waste.
{"title":"Study of properties of adhesive formed by waste polystyrene","authors":"Shaan Tahilramani, Dharmik R Shah, B. Patel, Chirag Vidja, Endrick Contractor","doi":"10.31254/jsir.2020.9207","DOIUrl":"https://doi.org/10.31254/jsir.2020.9207","url":null,"abstract":"The polystyrene products involved in day to day life serve to its best as per its utility. I t possesses the several properties like Insulation, Light in weight, Cushioning, Non-Reactive Material and Non- Biodegradable. Serving multipurpose it finds wide application in food industry for food packaging, material packaging in the electrical device sector, construction sector etc. There are demerits associated with the product after use i.e. waste product disposal is the major problem incurred curre ntly. It is becoming a part of landfill and increasing the amount of solid waste. It can even harm animals that scavenge food from the landfills. Our project aims to reduce and develop methodologies to treat the polystyrene waste.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"116 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87924972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Prasad, S. Bhardwaj, S. Dwivedi, Y. Arora, V. Sharma
Introduction: The prevalence of coronary artery disease (CAD) has progressively -increased in India and is the major cause of morbidity and mortality burden in the world. Several strategies are available to reduce morbidity and mortality, including the interventional approach (eg, early revascularization with PCI and stenting) and the pharmacologic approach (eg, thrombolytic and anticoagulant therapies) and yoga 1,2 The various psychological responses to experiencing myocardial infarction are anxiety reactions, depression , agoraphobia , exhaustion, hostility , sadness , anger , disgust and social withdrawal. 3 Yoga has reported to decrease these incidences. Methodology: The study included 200 patients diagnosed as MI who were divided into two groups 100 cases of control group subjected to conventional treatment and lifestyle counseling while 100 cases in test group were treated with yoga in addition to conventional treatment and lifestyle modification. The primary outcome included change in risk factors from baseline to end of study. Secondary outcome included change in Depression score and MACE at the end of the study. Result -After 24 weeks of intervention, the difference among yoga and control group was found to be significant for following parameters- weight, BMI, waist circumference, post prandial blood sugar, HBA1c, HDL cholesterol, triglyceride, total cholesterol and depression score. A significant difference was not seen for mean CIMT. Conclusion: Yoga may be a cost-effective technique to target multiple risk factors of myocardial infarction. It can be recommended along with conventional treatment for prevention and improvement of outcome in MI patients
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