In Japan, labeling of packages of prescription drugs was changed from JAN (Japanese Article Number) codes to GS1 DataBars, and the use of GS1 DataBars in medical services is expected to aid in the prevention of medical accidents, such as drug mix-ups, and improve traceability. In Japan, prescription drugs are dispensed primarily using PTP (Press Through Package) and SP (Strip Package) sheets, and tablets and capsules are seldom given to patients in bottles as in the United States and EU countries. We carried out a questionnaire survey of hospital pharmacists who handle drugs as their job to investigate the viewpoints from which they evaluate the design of PTP sheets of drugs. When the position of the bar code was evaluated from the viewpoint of “readability”, there was little difference between the top and bottom of the PTP sheet, but there was a difference between the top (over the tablets) and the margin of the PTP sheet. To the question “Which is more functional, endless printing or pitch printing?”, the pitch method was selected twice as frequently. “Ergonomics of holding the drug with the left hand and holding the scanner with the right hand” were suggested to be important for rapid reading of GS1 DataBars with minimum movements during the complex dispensing operation.
{"title":"Questionnaire survey concerning the recognition of GS1 DataBars by hospital pharmacists","authors":"M. Murata, Eri Takeishi, H. Kanno, M. Sumi","doi":"10.31254/jsir.2020.9201","DOIUrl":"https://doi.org/10.31254/jsir.2020.9201","url":null,"abstract":"In Japan, labeling of packages of prescription drugs was changed from JAN (Japanese Article Number) codes to GS1 DataBars, and the use of GS1 DataBars in medical services is expected to aid in the prevention of medical accidents, such as drug mix-ups, and improve traceability. In Japan, prescription drugs are dispensed primarily using PTP (Press Through Package) and SP (Strip Package) sheets, and tablets and capsules are seldom given to patients in bottles as in the United States and EU countries. We carried out a questionnaire survey of hospital pharmacists who handle drugs as their job to investigate the viewpoints from which they evaluate the design of PTP sheets of drugs. When the position of the bar code was evaluated from the viewpoint of “readability”, there was little difference between the top and bottom of the PTP sheet, but there was a difference between the top (over the tablets) and the margin of the PTP sheet. To the question “Which is more functional, endless printing or pitch printing?”, the pitch method was selected twice as frequently. “Ergonomics of holding the drug with the left hand and holding the scanner with the right hand” were suggested to be important for rapid reading of GS1 DataBars with minimum movements during the complex dispensing operation.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82416377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salma Bilal, Akhtar Ali Shah, A. Shah, Hajera Gul, Wahid Ullah, Salma Gul
Polypyrrole/graphene oxide (PPyGO) composite was synthesized through in-situ emulsion oxidative polymerization method. The composite was simultaneously doped with dodecylbenzenesulphonic acid doped (DBSA). The reaction parameters were optimized in such a way to get the composite with best possible properties. Thus, the resulting composite showed enhanced conductivity that is 73 S/cm compared to DBSA doped polypyrrole (4.18 S/cm) and graphene oxide (0.57 S/cm). As, conductivity is very important characteristic for practical application of polymeric materials, so, this material with enhanced properties can be used for multiple purposes. It was further characterized through Fourier Transform infrared spectroscopy, X-Ray Diffraction Analysis, Scanning Electron Microscopy and Thermogravimetric Analysis, which showed the successful synthesis of the composite.
{"title":"Dodecylbenzenesulphonic Acid Doped Polypyrrole/Graphene Oxide Composite with Enhanced Electrical Conductivity","authors":"Salma Bilal, Akhtar Ali Shah, A. Shah, Hajera Gul, Wahid Ullah, Salma Gul","doi":"10.31254/jsir.2020.9204","DOIUrl":"https://doi.org/10.31254/jsir.2020.9204","url":null,"abstract":"Polypyrrole/graphene oxide (PPyGO) composite was synthesized through in-situ emulsion oxidative polymerization method. The composite was simultaneously doped with dodecylbenzenesulphonic acid doped (DBSA). The reaction parameters were optimized in such a way to get the composite with best possible properties. Thus, the resulting composite showed enhanced conductivity that is 73 S/cm compared to DBSA doped polypyrrole (4.18 S/cm) and graphene oxide (0.57 S/cm). As, conductivity is very important characteristic for practical application of polymeric materials, so, this material with enhanced properties can be used for multiple purposes. It was further characterized through Fourier Transform infrared spectroscopy, X-Ray Diffraction Analysis, Scanning Electron Microscopy and Thermogravimetric Analysis, which showed the successful synthesis of the composite.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90480831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The vitamins, functional and sensory attributes of wheat-cocoyam composite flour and its biscuit baking potential were studied using standard analytical methods. Cocoyam flour were produced and used to substitute wheat flour at different substitutional levels viz 90:10%, 80:20%, 70:30%, 60:40%, 50:50% with 100% wheat flour as control. The resultant biscuit produced showed that vitamin C ranged from 17.17-78.92mg/100g, vitamin B2 ranged from 8.02-35.96mg/100g, vitamin B5 varied from 0.08 to 0.05mg/100g, vitamin B6 ranged from 1.0- 6.20mg/100g while vitamin B9 ranged from 0.27-1.27mg/100g respectively. Fat soluble vitamins were present at appreciable amounts in the sample, revealing 0.45, 0.53, 0.68, 1.60, 2.28 and 5.67mg/100g for control,10%, 20%, 30%, 40% and 50% cocoyam flour substitution. Highest values of 380, 376, 367(mg/kg) were recorded by biscuits from 60:40%, 70:30% and 50:50% wheat cocoyam composite flour in terms of sodium content. Potassium also show significant levels, ranging from 83.53-193.83mg/kg. Whereas the functional properties of composited flour and sensory attributes of biscuits were deferred significantly (p≤0.05), textural quality of biscuits showed no significant (p≥0.05) difference. Wettability was found to increase with increase in cocoyam incorporation. However, biscuit of acceptable quality comparable to that of 100% with flour can be produced from 50:50 wheat-cocoyam flour blends, hence enhancing the utilization of cocoyam and reducing overdependence on wheat flour for baking products.
{"title":"Vitamins, Functional and Sensory Attributes of Biscuit Produced from Wheat-Cocoyam Composite Flour","authors":"O. M. Makanjuola, Olalekan J Adebowale","doi":"10.31254/jsir.2020.9208","DOIUrl":"https://doi.org/10.31254/jsir.2020.9208","url":null,"abstract":"The vitamins, functional and sensory attributes of wheat-cocoyam composite flour and its biscuit baking potential were studied using standard analytical methods. Cocoyam flour were produced and used to substitute wheat flour at different substitutional levels viz 90:10%, 80:20%, 70:30%, 60:40%, 50:50% with 100% wheat flour as control. The resultant biscuit produced showed that vitamin C ranged from 17.17-78.92mg/100g, vitamin B2 ranged from 8.02-35.96mg/100g, vitamin B5 varied from 0.08 to 0.05mg/100g, vitamin B6 ranged from 1.0- 6.20mg/100g while vitamin B9 ranged from 0.27-1.27mg/100g respectively. Fat soluble vitamins were present at appreciable amounts in the sample, revealing 0.45, 0.53, 0.68, 1.60, 2.28 and 5.67mg/100g for control,10%, 20%, 30%, 40% and 50% cocoyam flour substitution. Highest values of 380, 376, 367(mg/kg) were recorded by biscuits from 60:40%, 70:30% and 50:50% wheat cocoyam composite flour in terms of sodium content. Potassium also show significant levels, ranging from 83.53-193.83mg/kg. Whereas the functional properties of composited flour and sensory attributes of biscuits were deferred significantly (p≤0.05), textural quality of biscuits showed no significant (p≥0.05) difference. Wettability was found to increase with increase in cocoyam incorporation. However, biscuit of acceptable quality comparable to that of 100% with flour can be produced from 50:50 wheat-cocoyam flour blends, hence enhancing the utilization of cocoyam and reducing overdependence on wheat flour for baking products.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74135079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Singh, D. Sharma, Sweta B. Prajapati, Anchal Bamal, S. Tyagi
Cellulose is one of the most abundant polymers on earth. It is present in huge amount in the various wastes of agricultural produce. Cellulase enzyme can be produced by using these wastes. Cellulase enzyme has been produced by a wide range of microbial flora such as fungi and bacteria. Production conditions for the production of cellulase enzymes has been optimized using one factor variable at a time approach. Various production conditions such as carbon source, nitrogen source, pH, temperature, incubation temperature and inoculum size have to optimized for maximum enzyme production. This review describes the production of cellulase enzyme using various agricultural wastes, which are reported in the literature till now. In this, we have mentioned the various microbial species, which are able to produce cellulase under optimum conditions. In this we have also discusses the comparative production of cellulase enzyme using submerged and solid-state fermentation. In today’s world, due to wide role of industrial enzymes in commercial market makes them more popular and we have to focus on more research towards their production using cheap substrates. These substrates are available annually and also environmentally friendly to use. The above-mentioned methods are very useful for the production of cellulase by reducing disposal problem of these agro-wastes. These substrates are more efficiently consumed by a potential strain like microbes, plants, etc. for production of cellulase enzyme. By this review, we are trying to explore the more potent source of cellulase production both in terms of increased productivity as well as quality.
{"title":"A Comparative Study of Cellulase Production: Minireview","authors":"V. Singh, D. Sharma, Sweta B. Prajapati, Anchal Bamal, S. Tyagi","doi":"10.31254/jsir.2020.9206","DOIUrl":"https://doi.org/10.31254/jsir.2020.9206","url":null,"abstract":"Cellulose is one of the most abundant polymers on earth. It is present in huge amount in the various wastes of agricultural produce. Cellulase enzyme can be produced by using these wastes. Cellulase enzyme has been produced by a wide range of microbial flora such as fungi and bacteria. Production conditions for the production of cellulase enzymes has been optimized using one factor variable at a time approach. Various production conditions such as carbon source, nitrogen source, pH, temperature, incubation temperature and inoculum size have to optimized for maximum enzyme production. This review describes the production of cellulase enzyme using various agricultural wastes, which are reported in the literature till now. In this, we have mentioned the various microbial species, which are able to produce cellulase under optimum conditions. In this we have also discusses the comparative production of cellulase enzyme using submerged and solid-state fermentation. In today’s world, due to wide role of industrial enzymes in commercial market makes them more popular and we have to focus on more research towards their production using cheap substrates. These substrates are available annually and also environmentally friendly to use. The above-mentioned methods are very useful for the production of cellulase by reducing disposal problem of these agro-wastes. These substrates are more efficiently consumed by a potential strain like microbes, plants, etc. for production of cellulase enzyme. By this review, we are trying to explore the more potent source of cellulase production both in terms of increased productivity as well as quality.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87042415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-30DOI: 10.36648/2249-7412.21.11.141-143
Degnechew Genene
Production of sustainable and renewable energy source from locally available biomass feedstock’s provides great opportunities to achieve sustainable growth and development in economic, social and environmental aspects for all nations across the globe. This study focused on production and characterization of charcoal briquettes from forest biomasses such as, Oxytenanthera abyssinica, Arundinaria alpina, Acacia mellifera and Prosopis juliflora, which were collected from different regions of Ethiopia (Amhara, Oromia and Somali). The experiment was conducted to determine moisture content (MC), volatile matter (VM), ash content (AC), calorific value (CV), fixed carbon (FC) and sulfur content (SC). The results were analyzed by using Statistical Analysis System (SAS) software. The analysis indicated that the effect of parameters considered in the experiment (i.e. Temperature, Binder ratio, Number of press and pressure) on the four species type and sample types were significant at level of probability, P = 0.0001. Maximum amount of MC was recorded for P. juliflora samples (i.e. Sawdust, Charcoal and Briquette) with respective values of 7.95%, 6.70 % and 6.88 %. The minimum amount of moisture was recorded on A. alpina’s Sawdust with value of 5 % and A. mellifera Charcoal with value of 5.29 %. Moreover, the least amount of VM (17.31 %) was found in biomass briquettes produced from A. alpina species and have better fuel quality in comparison with the other species. The maximum CV was recorded on Densified Biomass Briquette (DBB) obtained from A. alpina and P. juliflora with the values of 7106.8 cal/gm and 6755.6 cal/gm, respectively. The study suggested that charcoal briquette produced from selected species exhibits good fuel characteristics (i.e. higher CV, less MC, and high level of FC, and low SC) in compliance with the international acceptable standard. Therefore, the obtained research output in the study encourages proper utilization of the biomass feedstock’s for consumers and insure healthier environment via the supply of renewable source of energy
{"title":"Production and Characterization of Charcoal Briquette from Oxytenanthera abyssinica, Arundinaria alpina, Acacia melifera and Prosopis juliflora","authors":"Degnechew Genene","doi":"10.36648/2249-7412.21.11.141-143","DOIUrl":"https://doi.org/10.36648/2249-7412.21.11.141-143","url":null,"abstract":"Production of sustainable and renewable energy source from locally available biomass feedstock’s provides great opportunities to achieve sustainable growth and development in economic, social and environmental aspects for all nations across the globe. This study focused on production and characterization of charcoal briquettes from forest biomasses such as, Oxytenanthera abyssinica, Arundinaria alpina, Acacia mellifera and Prosopis juliflora, which were collected from different regions of Ethiopia (Amhara, Oromia and Somali). The experiment was conducted to determine moisture content (MC), volatile matter (VM), ash content (AC), calorific value (CV), fixed carbon (FC) and sulfur content (SC). The results were analyzed by using Statistical Analysis System (SAS) software. The analysis indicated that the effect of parameters considered in the experiment (i.e. Temperature, Binder ratio, Number of press and pressure) on the four species type and sample types were significant at level of probability, P = 0.0001. Maximum amount of MC was recorded for P. juliflora samples (i.e. Sawdust, Charcoal and Briquette) with respective values of 7.95%, 6.70 % and 6.88 %. The minimum amount of moisture was recorded on A. alpina’s Sawdust with value of 5 % and A. mellifera Charcoal with value of 5.29 %. Moreover, the least amount of VM (17.31 %) was found in biomass briquettes produced from A. alpina species and have better fuel quality in comparison with the other species. The maximum CV was recorded on Densified Biomass Briquette (DBB) obtained from A. alpina and P. juliflora with the values of 7106.8 cal/gm and 6755.6 cal/gm, respectively. The study suggested that charcoal briquette produced from selected species exhibits good fuel characteristics (i.e. higher CV, less MC, and high level of FC, and low SC) in compliance with the international acceptable standard. Therefore, the obtained research output in the study encourages proper utilization of the biomass feedstock’s for consumers and insure healthier environment via the supply of renewable source of energy","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"191 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74886045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mango (Mangifera indica) is the main tropical fruit of Asia and has developed its prominence all over the world. Mango wastes such as peels and seeds generated from fruit are a good source of functional ingredients out of which important ones are phenolic compounds with potent antioxidant properties. The quantification of gallic acid (GA), protocatechuic acid (PCA) and mangiferin (MGF) in the seed and peel extracts of three different varieties of mango fruit was performed by a novel, simple, specific, linear, precise, accurate and economic RPHPLC (reversed-phase high- performance liquid chromatography) method. The chromatographic separation was achieved on the C18 analytical column with a flow rate of 1.2 mL/min in an isocratic mode using 0.2% orthophosphoric acid and acetonitrile in the ratio 90:10 as the mobile phase. The column temperature was maintained at 40 ℃ and observations were recorded at 242 nm. The retention time of gallic acid, protocatechuic acid and mangiferin was observed at 3.41, 5.50, and 14.6 min respectively. The developed method when validated as per ICH guidelines was found to be specific, linear, precise, robust and accurate
{"title":"Novel HPLC method for simultaneous estimation of gallic acid, protocatechuic acid and mangiferin in mango","authors":"V. Jain, Yashaswini Paskanti","doi":"10.31254/jsir.2020.9103","DOIUrl":"https://doi.org/10.31254/jsir.2020.9103","url":null,"abstract":"Mango (Mangifera indica) is the main tropical fruit of Asia and has developed its prominence all over the world. Mango wastes such as peels and seeds generated from fruit are a good source of functional ingredients out of which important ones are phenolic compounds with potent antioxidant properties. The quantification of gallic acid (GA), protocatechuic acid (PCA) and mangiferin (MGF) in the seed and peel extracts of three different varieties of mango fruit was performed by a novel, simple, specific, linear, precise, accurate and economic RPHPLC (reversed-phase high- performance liquid chromatography) method. The chromatographic separation was achieved on the C18 analytical column with a flow rate of 1.2 mL/min in an isocratic mode using 0.2% orthophosphoric acid and acetonitrile in the ratio 90:10 as the mobile phase. The column temperature was maintained at 40 ℃ and observations were recorded at 242 nm. The retention time of gallic acid, protocatechuic acid and mangiferin was observed at 3.41, 5.50, and 14.6 min respectively. The developed method when validated as per ICH guidelines was found to be specific, linear, precise, robust and accurate","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86145349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This work concerned the valorization of shea butter, palm, coconut and kolo oils and, essential oils from Eucalyptus citriodora, Ocimum gratissimum, Cymbopogan citratus and Plectranthus glandulosus by applying a few stages of quality management procedures for soap making. For this purpose, the consumers' needs regarding the soap quality characteristics have been identified. It emerged that the soap smell was of more concern to them. The product was then designed by mixture design of experiment and, 50 g soap samples produced were subject to consumer assessment. Results showed that samples made with coconut (25 g) and kolo (25 g) oils gave the most popular soap according to the rates they received. Among the data of the four quality characteristics, only those from physical measurements of foam height suited the quadratic model. This lead to optimize this characteristic and the values of variables found were coco (17.171 g) and kolo (32.829 g) for a 9 cm maximum and 8 cm minimum foam height. There was no significant discrimination between both the odors of lemongrass and waya essential oils tested. The soaps perfumed with essential oils from Eucalyptus citriodora, Ocimum basilicum and Plectranthus glandulosus exerted an antimicrobial activity against Bacillus subtilis, Pseudomonas aeruginosa and Staphylococcus aureus.
{"title":"Quality improvement of soaps perfumed with some selected essential oils","authors":"Mikolo Bertin, Tsoumou Kedar, Massamba Daniel","doi":"10.31254/jsir.2020.9101","DOIUrl":"https://doi.org/10.31254/jsir.2020.9101","url":null,"abstract":"This work concerned the valorization of shea butter, palm, coconut and kolo oils and, essential oils from Eucalyptus citriodora, Ocimum gratissimum, Cymbopogan citratus and Plectranthus glandulosus by applying a few stages of quality management procedures for soap making. For this purpose, the consumers' needs regarding the soap quality characteristics have been identified. It emerged that the soap smell was of more concern to them. The product was then designed by mixture design of experiment and, 50 g soap samples produced were subject to consumer assessment. Results showed that samples made with coconut (25 g) and kolo (25 g) oils gave the most popular soap according to the rates they received. Among the data of the four quality characteristics, only those from physical measurements of foam height suited the quadratic model. This lead to optimize this characteristic and the values of variables found were coco (17.171 g) and kolo (32.829 g) for a 9 cm maximum and 8 cm minimum foam height. There was no significant discrimination between both the odors of lemongrass and waya essential oils tested. The soaps perfumed with essential oils from Eucalyptus citriodora, Ocimum basilicum and Plectranthus glandulosus exerted an antimicrobial activity against Bacillus subtilis, Pseudomonas aeruginosa and Staphylococcus aureus.","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83418406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sneha kalpana is one of the pharmaceutics which are used extensively in the field of Ayurveda for various disorders. It is one of the widely used techniques in Ayurvedic industries to achieve solubility of both fat- and water-soluble extractive into lipid medium through Agni paka as well as Adithya paka. Adithya paka is the method of taila paka where the taila yoga is prepared by exposing it into sunlight. There is very minimum reference regarding procedure of adithya paka which are scattered in classics. Among those tailas Stree Kutaja taila is been used widely in clinical practice for all type of skin disorders especially those which is caused by autoimmune malfunctioning. The properties of Stree Kutaja and Narikela taila helps in alleviating skin diseases where the Adithya paka Samskara will enhance the efficacy of taila. This paper consists of detailed procedure of Stree kutaja taila preparation and therapeutic action on autoimmune skin disorders with its probable mode of action
{"title":"Pharmaceutical and therapeutical study of Stree Kutaja Taila with special reference to autoimmune skin disorders","authors":"Sushma Shenoy U, Ashok Kumar B N","doi":"10.31254/jsir.2020.9102","DOIUrl":"https://doi.org/10.31254/jsir.2020.9102","url":null,"abstract":"Sneha kalpana is one of the pharmaceutics which are used extensively in the field of Ayurveda for various disorders. It is one of the widely used techniques in Ayurvedic industries to achieve solubility of both fat- and water-soluble extractive into lipid medium through Agni paka as well as Adithya paka. Adithya paka is the method of taila paka where the taila yoga is prepared by exposing it into sunlight. There is very minimum reference regarding procedure of adithya paka which are scattered in classics. Among those tailas Stree Kutaja taila is been used widely in clinical practice for all type of skin disorders especially those which is caused by autoimmune malfunctioning. The properties of Stree Kutaja and Narikela taila helps in alleviating skin diseases where the Adithya paka Samskara will enhance the efficacy of taila. This paper consists of detailed procedure of Stree kutaja taila preparation and therapeutic action on autoimmune skin disorders with its probable mode of action","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76574560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Pre-eclampsia is a major direct cause of maternal mortality second only to hemorrhage with 50,000-60,000 pre-eclampsia related deaths worldwide annually. Pregnancies complicated by preeclampsia require close fetal surveillance to guide management and improve outcomes. Poor Biophysical profile scores are associated with poor perinatal outcomes. Recent research has however shown that Doppler flow changes occur much earlier and can be used to time delivery with better perinatal outcomes. Objective: To compare Doppler indices of the umbilical and middle cerebral arteries with biophysical profile scores in the prediction of perinatal outcomes in patients with pre-eclampsia. Methods: This was a cross sectional study. Patients with preeclampsia above 28 weeks gestation were consecutively sampled, questionnaires administered, ultrasound done, followed up to delivery and outcomes documented. Statistical analysis was done using STATA/MP version 13.0. Results: One hundred and sixty-five patients whose ages ranged from 15-42 years with an average of 29 years were studied. Majority (72.7%) presented between 28-34 weeks and 66.06% had pre-eclampsia with severe features. An abnormal outcome was seen in 86.4% of those who had abnormal Biophysical Profile (BPP) scores and abnormal BPP increased the Odds of poor outcome 4.95 times (p<0.001). An abnormal outcome was seen in 80% of those who had abnormal Doppler findings and abnormal Doppler findings increased the Odds of poor perinatal outcome 11.5 times (p<0.001). Conclusion: Abnormal BPP and Doppler findings were significantly associated with poor perinatal outcomes with Doppler being a better predictor
背景:子痫前期是孕产妇死亡的主要直接原因，仅次于出血，全世界每年有50,000-60,000例子痫前期相关死亡。妊娠合并先兆子痫需要密切的胎儿监测，以指导管理和改善结果。较差的生物物理特征评分与较差的围产期结局相关。然而，最近的研究表明，多普勒血流变化发生得更早，可以用来确定分娩时间，围产期结局更好。目的:比较脐部和大脑中动脉多普勒指数与生物物理谱评分对子痫前期围产儿预后的预测价值。方法:采用横断面研究。对妊娠28周以上的先兆子痫患者进行连续抽样，进行问卷调查，超声检查，随访至分娩并记录结果。统计分析使用STATA/MP version 13.0进行。结果:共纳入165例患者，年龄15 ~ 42岁，平均29岁。大多数(72.7%)出现在28-34周之间，66.06%为重度先兆子痫。生物物理特征(BPP)评分异常者出现异常结局的比例为86.4%，BPP评分异常使不良结局的发生率增加4.95倍(p<0.001)。有异常多普勒检查结果的患者中有80%出现异常结局，异常多普勒检查结果使围产儿预后不良的几率增加11.5倍(p<0.001)。结论:异常的BPP和多普勒检查结果与围产儿预后不良显著相关，多普勒是一个更好的预测指标
{"title":"Comparison of Biophysical Profile Score with Fetal Doppler Ultrasound in Patients with Pre-eclampsia at Moi Teaching and Referral Hospital, Kenya","authors":"Mbarak Nuru, Abuya Joseph, Kaaria Alice","doi":"10.31254/jsir.2020.9106","DOIUrl":"https://doi.org/10.31254/jsir.2020.9106","url":null,"abstract":"Background: Pre-eclampsia is a major direct cause of maternal mortality second only to hemorrhage with 50,000-60,000 pre-eclampsia related deaths worldwide annually. Pregnancies complicated by preeclampsia require close fetal surveillance to guide management and improve outcomes. Poor Biophysical profile scores are associated with poor perinatal outcomes. Recent research has however shown that Doppler flow changes occur much earlier and can be used to time delivery with better perinatal outcomes. Objective: To compare Doppler indices of the umbilical and middle cerebral arteries with biophysical profile scores in the prediction of perinatal outcomes in patients with pre-eclampsia. Methods: This was a cross sectional study. Patients with preeclampsia above 28 weeks gestation were consecutively sampled, questionnaires administered, ultrasound done, followed up to delivery and outcomes documented. Statistical analysis was done using STATA/MP version 13.0. Results: One hundred and sixty-five patients whose ages ranged from 15-42 years with an average of 29 years were studied. Majority (72.7%) presented between 28-34 weeks and 66.06% had pre-eclampsia with severe features. An abnormal outcome was seen in 86.4% of those who had abnormal Biophysical Profile (BPP) scores and abnormal BPP increased the Odds of poor outcome 4.95 times (p<0.001). An abnormal outcome was seen in 80% of those who had abnormal Doppler findings and abnormal Doppler findings increased the Odds of poor perinatal outcome 11.5 times (p<0.001). Conclusion: Abnormal BPP and Doppler findings were significantly associated with poor perinatal outcomes with Doppler being a better predictor","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84729738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The effect of synthesis temperature on percentage yield, thermal stability, surface morphology, crystallinity, and conductivity of polyaniline doped with dodecylbenzenesulfonic acid (PANI-DBSA) was studied. PANI-DBSA was synthesized at and the 5, 10,20, 25 and 30 0C and the percent yield of the product was determined. Furthermore, thermo gravimetric analysis (TGA), scanning electron microscopy (SEM), X-ray diffraction (XRD), UV-Visible spectrophotometry and cyclic voltammetry (CV) were utilized to inspect the variation in different physicochemical properties of the synthesized polymer with changing synthesis temperature
{"title":"Effect of Synthesis Temperature on Properties of Polyaniline","authors":"Salma Bilal, Adil Jehan, S. Rahman, A. Shah","doi":"10.31254/jsir.2020.9105","DOIUrl":"https://doi.org/10.31254/jsir.2020.9105","url":null,"abstract":"The effect of synthesis temperature on percentage yield, thermal stability, surface morphology, crystallinity, and conductivity of polyaniline doped with dodecylbenzenesulfonic acid (PANI-DBSA) was studied. PANI-DBSA was synthesized at and the 5, 10,20, 25 and 30 0C and the percent yield of the product was determined. Furthermore, thermo gravimetric analysis (TGA), scanning electron microscopy (SEM), X-ray diffraction (XRD), UV-Visible spectrophotometry and cyclic voltammetry (CV) were utilized to inspect the variation in different physicochemical properties of the synthesized polymer with changing synthesis temperature","PeriodicalId":17221,"journal":{"name":"Journal of Scientific and Innovative Research","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91059881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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