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Predictive Factors for Retreatment after Intravitreal Ranibizumab Injection to Treat Type 1 Retinopathy of Prematurity 玻璃体内注射雷尼单抗治疗早产儿1型视网膜病变后再治疗的预测因素
Q4 Medicine Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.793
Su Hwan Park, Iksoo Byon, Han Jo Kwon
Purpose: To investigate predictive factors for retreatment after intravitreal ranibizumab injection as first-line treatment for retinopathy of prematurity (ROP).Methods: The medical records of consecutive infants diagnosed with type 1 ROP from 2013 to 2021 who received 0.2 mg intravitreal ranibizumab as their first treatments were retrospectively reviewed. Only eyes with severe ROP were included. Retreatment was performed if eyes again met the criteria for type 1 ROP or presented with stage 3 ROP and the plus sign. Factors around the time of first injection that predicted retreatment were assessed.Results: Intravitreal ranibizumab was injected into 44 eyes of 44 infants. The mean gestational age (GA) and body weight were 27.8 weeks and 1,046.6 g, respectively. Retreatment was required by 21 eyes (47.7%) at an average of 8.9 weeks after the first injection, thus at 37.2 weeks of mean postmenstrual age. The retreatment group exhibited a lower GA (p = 0.036), lower 1 minute (min) (p = 0.014) and 5 min (p = 0.029) Apgar scores, and more quadrants with plus signs (p = 0.044) before the first injections; they also had a longer period of oxygen requirement (p = 0.001), more loss of the plus sign (p = 0.014), and more ROP involution (p = 0.003) after the first injections. The risk of needing retreatment increased with a lower 1 min Apgar score (p = 0.010, odds ratio [OR] = 2.04) and later disappearance of the plus sign (p = 0.013, OR = 1.44) after the first injection.Conclusions: About half of patients with type 1 ROP may require retreatment 2 months after the first ranibizumab injection. Delayed loss of the plus sign increases the risk of retreatment; careful fundus examination is recommended after the first injection.
目的:探讨雷尼单抗玻璃体内注射作为一线治疗早产儿视网膜病变(ROP)后再治疗的预测因素。方法:回顾性分析2013年至2021年连续诊断为1型ROP的婴儿首次接受0.2 mg玻璃体内注射雷尼单抗治疗的病历。只包括严重ROP的眼睛。如果眼睛再次符合1型ROP的标准或出现3期ROP和加号,则进行再治疗。评估了第一次注射前后预测再治疗的因素。结果:44例婴儿44眼玻璃体内注射雷尼单抗。平均胎龄27.8周,平均体重1046.6 g。21只眼(47.7%)在第一次注射后平均8.9周需要再次治疗,因此平均月经后年龄为37.2周。再治疗组GA较低(<i>p</i>= 0.036),降低1分钟(分钟)(& lt; i>术中;/ i>= 0.014)和5分钟(<i>p</i>= 0.029) Apgar分数,以及更多带有加号的象限(<i>p</i>= 0.044);它们也有更长的氧气需求期(<i>p</i>= 0.001),更多的加号丢失(<i>p</i>= 0.014), ROP对合度更高(<i>p</i>= 0.003)。1分钟Apgar评分越低,需要再治疗的风险越高(<i>p</i>= 0.010,优势比[OR] = 2.04),加号(<i>p</i>= 0.013, OR = 1.44)。结论:大约一半的1型ROP患者在首次注射雷尼单抗2个月后可能需要再次治疗。加号的延迟丢失增加了再治疗的风险;建议在第一次注射后仔细检查眼底。
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引用次数: 0
Clinical Outcomes of Boston Type-I Keratoprosthesis Implantation: A 4-year Retrospective Study in South Korea 波士顿i型人工角膜植入术的临床结果:韩国4年回顾性研究
IF 0.1 Q4 Medicine Pub Date : 2023-08-15 DOI: 10.3341/jkos.2023.64.8.672
Jiyeon Han, Soomin Lee, Y. Won, D. Lim, Tae-Young Chung
Purpose: To evaluate the long-term results of Boston type-I keratoprosthesis implantation in Korea.Methods: Medical records of six patients (six eyes) who underwent Boston type-I keratoprosthesis implantation between August 2018 and November 2019 were retrospectively reviewed for more than 36 months.Results: The mean follow-up period was 44.3 ± 7.0 months. Best corrected visual acuity (BCVA) improved significantly for all six eyes, from 2.33 ± 0.51 logarithm of the minimum angle of resolution (logMAR) to 0.67 ± 0.59 logMAR. The vision recovered immediately after the surgery in all patients. Retroprosthetic membrane developed in three of the patients, but the visual acuity remained unchanged. Anatomical success was achieved in all six eyes after Boston type-I keratoprosthesis implantation.Conclusions: The long-term analysis of Boston type-I keratoprosthesis implantation showed a faster recovery and improved visual acuity compared with conventional penetrating keratoplasty. Without the use of systemic immunosuppressants, all six eyes showed long-term survival of the Boston keratoprosthesis. Boston type-I keratoprosthesis implantation may be used in patients with recurrent graft failure after keratoplasty. This was the first study investigating the long-term results of Boston keratoprosthesis implantation in Korean patients.
目的:评估在韩国进行Boston I型角膜植入术的长期效果。方法:回顾性分析2018年8月至2019年11月期间接受Boston I类型角膜植入术36个多月的6名患者(6眼)的病历。结果:平均随访时间为44.3±7.0个月。所有6只眼睛的最佳矫正视力(BCVA)均显著提高,从最小分辨角(logMAR)的2.33±0.51对数提高到0.67±0.59 logMAR。所有患者的视力在手术后立即恢复。其中三名患者出现假体后膜,但视力保持不变。Boston I型人工角膜植入术后,6只眼睛在解剖学上均获得成功。结论:Boston I型人工角膜植入术的远期分析显示,与传统穿透性角膜移植术相比,该术恢复更快,视力提高。在不使用全身免疫抑制剂的情况下,所有六只眼睛都显示出波士顿角膜假体的长期存活率。Boston I型人工角膜植入术可用于角膜移植术后复发性移植物衰竭的患者。这是第一项对韩国患者植入波士顿角膜假体的长期结果进行调查的研究。
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引用次数: 0
Clinical Outcomes of ATOS-mediated SmartSight Lenticule Extraction atos介导的SmartSight晶状体提取的临床结果
IF 0.1 Q4 Medicine Pub Date : 2023-08-15 DOI: 10.3341/jkos.2023.64.8.666
Chang Mok Lee, Hyo Sung Yoon, Hyera Kang, Mingue Kim, Sheen Chull Joh, D. Yeom
Purpose: To evaluate the clinical outcomes of a new refractive corneal lenticule extraction method (SmartSight) using a Schwind ATOS femtosecond laser (Schwind Eye-Tech-Solutions, Kleinostheim, Germany).Methods: The medical records of 338 eyes of 170 patients who underwent SmartSight treatment from April to September 2022 and were followed-up for at least 3 months were retrospectively analyzed. The patients were followed-up at 1 day, 1 week, and 1 and 3 months after operation. Refraction, visual acuity, and intraocular pressure were measured at each visit.Results: Preoperatively, the uncorrected distant visual acuity was 1.26 ± 0.33 logarithm of minimum angle or resolution (logMAR) and the spherical equivalent was -4.52 ± 1.77 diopters. The 3-month, postoperative, uncorrected distant visual acuity was 0.01 ± 0.03 logMAR and the spherical equivalent was -0.12 ± 0.22 diopters. The 3-month data were as follows: efficacy of refractive surgery, 0.99 ± 0.11; safety, 1.00 ± 0.05; predictabilities at ±0.5 and ± 1.0 diopters, 97% and 100%, respectively.Conclusions: Myopic astigmatism correction using the SmartSight method was effective, safe, and predictable in terms of visual outcomes.
目的:评价一种使用Schwind ATOS飞秒激光(Schwind Eye-Tech-Solutions, Kleinostheim, Germany)的新型屈光性角膜晶状体摘除方法(SmartSight)的临床效果。方法:对2022年4月~ 9月接受SmartSight治疗的170例患者338只眼的病历进行回顾性分析,随访时间不少于3个月。术后1天、1周、1个月、3个月随访。每次就诊均测量屈光、视力和眼压。结果:术前未矫正远视灵敏度为1.26±0.33对数最小角度或分辨率(logMAR),球面等效度为-4.52±1.77屈光度。术后3个月未矫正远视灵敏度为0.01±0.03 logMAR,球面等效度为-0.12±0.22屈光度。3个月数据如下:屈光手术疗效,0.99±0.11;安全性,1.00±0.05;在±0.5和±1.0屈光度下的可预测性分别为97%和100%。结论:使用SmartSight方法矫正近视散光在视力方面是有效、安全、可预测的。
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引用次数: 0
Environmental Effects on Dry Eyes in Primary Sjogren's Syndrome 环境对原发性干燥综合征干眼症的影响
IF 0.1 Q4 Medicine Pub Date : 2023-08-15 DOI: 10.3341/jkos.2023.64.8.680
Joo Ye Park, H. Paik, Dong Hyun Kim
Purpose: To investigate the effects of humidity, temperature, and fine particulate matter (PM2.5) on dry eye disease (DED) parameters in primary Sjogren's syndrome patients.Methods: We retrospectively analyzed the medical records of 18 primary Sjogren's syndrome patients who underwent DED treatment and had more than two follow-up visits. Symptom Assessment in Dry Eye (SANDE) scores, tear secretion, tear film breakup times, ocular surface staining scores, and tear osmolarity were assessed. Temperature, humidity, and PM2.5 concentrations during the week before the patient visits were calculated using public data and their relationships with DED parameters were analyzed.Results: All patients were females, with an average age of 57.6 ± 12.4 years. High temperature was significantly correlated with humidity and PM2.5 concentration (p = 0.004 and = 0.006, respectively). The high humidity, high temperature, and low PM2.5 groups had lower SANDE scores (p = 0.017, = 0.063, and = 0.049, respectively) and tear osmolarity (p < 0.001, = 0.009, and < 0.001, respectively). Multiple regression analysis showed that temperature and humidity had stronger correlations with tear osmolarity (p = 0.005 and = 0.012, respectively) compared to PM2.5 concentrations.Conclusions: Ocular discomfort and tear osmolarity were correlated with temperature, humidity, and PM2.5 concentrations. Among the DED parameters, tear osmolarity was the most sensitive indicator of exposure to environmental factors.
目的:研究湿度、温度和细颗粒物(PM2.5)对原发性干燥综合征患者干眼病(DED)参数的影响。方法:我们回顾性分析了18例原发性干燥综合征患者的医疗记录,这些患者接受了DED治疗并进行了两次以上的随访。评估干眼症状评估(SANDE)评分、泪液分泌、泪膜破裂次数、眼表染色评分和泪液渗透压。使用公共数据计算患者就诊前一周的温度、湿度和PM2.5浓度,并分析它们与DED参数的关系。结果:所有患者均为女性,平均年龄57.6±12.4岁。高温与湿度和PM2.5浓度显著相关(分别为p=0.004和=0.006)。高湿度、高温和低PM2.5组的SANDE评分较低(分别为p=0.017、=0.063和=0.049)和泪液渗透压(分别为p<0.001、=0.009和<0.001)。多元回归分析表明,与PM2.5浓度相比,温度和湿度与泪液渗透压的相关性更强(分别为0.005和0.012)。结论:眼部不适和泪液渗透压与温度、湿度和PM2.5浓度有关。在DED参数中,泪液渗透压是暴露于环境因素的最敏感指标。
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引用次数: 0
A Case of Hypertensive Anterior Uveitis with Endotheliitis of the Cornea Following COVID-19 Pneumonia COVID-19肺炎合并高血压性前葡萄膜炎并发角膜内皮炎1例
IF 0.1 Q4 Medicine Pub Date : 2023-08-15 DOI: 10.3341/jkos.2023.64.8.743
Young‐Ho Noh, Jin A Choi
Purpose: We report a patient diagnosed with COVID-19-associated hypertensive anterior uveitis and endotheliitis of the cornea.Case Summary: A 71-year-old male visited our hospital with decreased visual acuity, ocular pain, eyelid swelling of in his right eye, and headache for 8 days. He had been diagnosed with COVID-19 pneumonia 10 days before the visit. The best-corrected visual acuity was 0.04 in his right eye and 0.15 in his left eye. Severe conjunctival injection, moderate corneal edema with Descemet membrane folding, diffuse keratic precipitates and mild anterior chamber reaction were observed in the right eye, which were not present in the previous examination. Pupils in both eyes were moderately dilated and slow to react in response to direct light. The density of endothelial cells in the right eye was 711 cells/mm2 and an owl’s eye morphology of endothelial cells was observed via specular microscopy. During follow up, elevated intraocular pressure (IOP) in the right eye was noted. Polymerase chain reaction (PCR) examination of the aqueous humor for cytomegalovirus was negative. After 2 weeks of applying prednisolone eye drops and anti-glaucoma eye drops, corneal edema decreased, and his vision improved to 0.5. However, the density of the corneal endothelium remained low.Conclusions: Although there have been worldwide case reports of conjunctivitis, keratitis, or uveitis after COVID-19 infection, this study presents the first reported case of COVID-19 associated hypertensive anterior uveitis and endotheliitis of the cornea.
目的:我们报告一例被诊断为covid -19相关性高血压前葡萄膜炎和角膜内皮炎的患者。病例总结:71岁男性患者因视力下降、眼部疼痛、右眼眼睑肿胀、头痛8天来我院就诊。他在访问前10天被诊断出患有COVID-19肺炎。右眼最佳矫正视力0.04,左眼最佳矫正视力0.15。右眼严重结膜注射、中度角膜水肿伴Descemet膜折叠、弥漫性角沉淀及轻度前房反应,均为既往检查未见。双眼瞳孔适度放大,对光直射反应缓慢。右眼内皮细胞密度为711个/mm2,镜下观察猫头鹰眼内皮细胞形态。随访中发现右眼眼压升高。聚合酶链反应(PCR)检测巨细胞病毒房水呈阴性。泼尼松龙滴眼液和抗青光眼滴眼液应用2周后,角膜水肿减轻,视力改善至0.5。然而,角膜内皮的密度仍然很低。结论:虽然全球已有COVID-19感染后结膜炎、角膜炎或葡萄膜炎的病例报道,但本研究首次报道了COVID-19相关高血压前葡萄膜炎和角膜内皮炎。
{"title":"A Case of Hypertensive Anterior Uveitis with Endotheliitis of the Cornea Following COVID-19 Pneumonia","authors":"Young‐Ho Noh, Jin A Choi","doi":"10.3341/jkos.2023.64.8.743","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.8.743","url":null,"abstract":"Purpose: We report a patient diagnosed with COVID-19-associated hypertensive anterior uveitis and endotheliitis of the cornea.Case Summary: A 71-year-old male visited our hospital with decreased visual acuity, ocular pain, eyelid swelling of in his right eye, and headache for 8 days. He had been diagnosed with COVID-19 pneumonia 10 days before the visit. The best-corrected visual acuity was 0.04 in his right eye and 0.15 in his left eye. Severe conjunctival injection, moderate corneal edema with Descemet membrane folding, diffuse keratic precipitates and mild anterior chamber reaction were observed in the right eye, which were not present in the previous examination. Pupils in both eyes were moderately dilated and slow to react in response to direct light. The density of endothelial cells in the right eye was 711 cells/mm2 and an owl’s eye morphology of endothelial cells was observed via specular microscopy. During follow up, elevated intraocular pressure (IOP) in the right eye was noted. Polymerase chain reaction (PCR) examination of the aqueous humor for cytomegalovirus was negative. After 2 weeks of applying prednisolone eye drops and anti-glaucoma eye drops, corneal edema decreased, and his vision improved to 0.5. However, the density of the corneal endothelium remained low.Conclusions: Although there have been worldwide case reports of conjunctivitis, keratitis, or uveitis after COVID-19 infection, this study presents the first reported case of COVID-19 associated hypertensive anterior uveitis and endotheliitis of the cornea.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48250037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iris Metastasis of Non-small-cell Lung Cancer Confirmed via Aqueous Humor Cytology 房水细胞学证实非小细胞肺癌虹膜转移
IF 0.1 Q4 Medicine Pub Date : 2023-08-15 DOI: 10.3341/jkos.2023.64.8.749
Jiyeon Han, Y. Jang, J. Han
Purpose: To report an iris metastasis associated with non-small-cell lung cancer (NLC) confirmed via repeat aqueous humor cytology.Case summary: A 53-year-old female presented to our ophthalmology outpatient department with complaints of vision impairment and pain in the left eye 1 month in duration. In ophthalmologic examinations, the best-corrected visual acuities were 20/20 oculus dexter (OD) and 20/32 oculus sinister (OS). The intraocular pressures measured using standard Goldmann applanation tonometery were 12 mmHg OD and 42 mmHg OS. Slit-lamp examination revealed multiple iris nodules in the left eye. Thirteen months prior, the patient had been diagnosed with NLC and was on chemotherapy. Despite the maximal tolerated medical therapy, the intraocular pressure was not controlled. As an iris metastasis was suspected, anterior chamber paracentesis was performed for aqueous humor sampling. Cytological analysis did not reveal malignant cells. One week later, aqueous humor sampling was repeated. Malignant cells were histopathologically confirmed. Given the ocular metastasis, the oncologists changed the chemotherapy regimen.Conclusions: When an NLC patient exhibits iris nodules, repeat aqueous humor cytology can confirm an iris metastasis.
目的:报告一例经重复房水细胞学检查证实的与非小细胞肺癌相关的虹膜转移。病例总结:一名53岁的女性,在1个月内因视力受损和左眼疼痛而到我们的眼科门诊就诊。在眼科检查中,矫正视力最好的是20/20右眼(OD)和20/32左眼(OS)。使用标准Goldmann压平眼压计测量的眼压为12 mmHg OD和42 mmHg OS。裂隙灯检查显示左眼有多个虹膜结节。13个月前,患者被诊断为NLC,正在接受化疗。尽管进行了最大限度的药物治疗,但眼压没有得到控制。由于怀疑有虹膜转移,行前房穿刺房水取样。细胞学分析没有发现恶性细胞。一周后,重复房水取样。恶性细胞经组织病理学证实。考虑到眼部转移,肿瘤学家改变了化疗方案。结论:当NLC患者出现虹膜结节时,重复房水细胞学检查可以确认虹膜转移。
{"title":"Iris Metastasis of Non-small-cell Lung Cancer Confirmed via Aqueous Humor Cytology","authors":"Jiyeon Han, Y. Jang, J. Han","doi":"10.3341/jkos.2023.64.8.749","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.8.749","url":null,"abstract":"Purpose: To report an iris metastasis associated with non-small-cell lung cancer (NLC) confirmed via repeat aqueous humor cytology.Case summary: A 53-year-old female presented to our ophthalmology outpatient department with complaints of vision impairment and pain in the left eye 1 month in duration. In ophthalmologic examinations, the best-corrected visual acuities were 20/20 oculus dexter (OD) and 20/32 oculus sinister (OS). The intraocular pressures measured using standard Goldmann applanation tonometery were 12 mmHg OD and 42 mmHg OS. Slit-lamp examination revealed multiple iris nodules in the left eye. Thirteen months prior, the patient had been diagnosed with NLC and was on chemotherapy. Despite the maximal tolerated medical therapy, the intraocular pressure was not controlled. As an iris metastasis was suspected, anterior chamber paracentesis was performed for aqueous humor sampling. Cytological analysis did not reveal malignant cells. One week later, aqueous humor sampling was repeated. Malignant cells were histopathologically confirmed. Given the ocular metastasis, the oncologists changed the chemotherapy regimen.Conclusions: When an NLC patient exhibits iris nodules, repeat aqueous humor cytology can confirm an iris metastasis.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43412037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survey of Surgical Management in Intermittent Exotropia 间歇性外斜视手术治疗的探讨
IF 0.1 Q4 Medicine Pub Date : 2023-08-15 DOI: 10.3341/jkos.2023.64.8.727
S. Cho, Jeong-Min Hwang, H. Yang
Purpose: To obtain an overview of the surgical practices for the management of intermittent exotropia among experienced surgeons.Methods: We conducted a survey of members of the Korean Association for Pediatric Ophthalmology and Strabismus, who had experience of > 15 years in strabismus surgery, via e-mail. Surgical methods for basic-type intermittent exotropia, angle of deviation for determining the surgical dose, reasons for surgical dose adjustment, and the postoperative target angle of deviation were analyzed.Results: Bilateral lateral rectus recession was preferred over unilateral recession and resection for basic-type intermittent exotropia with or without a dominant eye. The preoperative maximum angle of deviation was preferred for determining the surgical dose by 56% of the participants. Two-thirds of the participants preferred to reduce the surgical dose in specific circumstances, lateral incomitancy being the most common reason. In case of true divergence excess-type intermittent exotropia, 47.7% of the participants reduced the surgical dose. The most preferred target angle of deviation at 1 day postoperatively was 11-15 prism diopter esodeviation, as reported by 40% of the participants.Conclusions: Although experienced surgeons had different surgical preferences for intermittent exotropia, a general trend was found. This survey may be a useful reference for beginners in strabismus surgery.
目的:总结经验丰富的外科医生治疗间歇性外斜视的手术方法。方法:我们通过电子邮件对韩国儿童眼科和斜视协会的成员进行了调查,他们在斜视手术方面有150年的经验。分析了基型间歇性外斜视的手术方法、确定手术剂量的偏向角、调整手术剂量的原因、术后目标偏向角。结果:对于有或无主眼的基本型间歇性外斜视,双侧直肌后退优于单侧直肌后退和切除。56%的参与者首选术前最大偏移角来确定手术剂量。三分之二的参与者倾向于在特定情况下减少手术剂量,侧部不适是最常见的原因。对于真正的发散过度型间歇性外斜视,47.7%的参与者减少了手术剂量。术后1天最理想的目标偏差角为11-15棱镜屈光度内偏差,有40%的参与者报告。结论:虽然经验丰富的外科医生对间歇性外斜视有不同的手术选择,但有一个普遍的趋势。这项调查对斜视手术的初学者有一定的参考价值。
{"title":"Survey of Surgical Management in Intermittent Exotropia","authors":"S. Cho, Jeong-Min Hwang, H. Yang","doi":"10.3341/jkos.2023.64.8.727","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.8.727","url":null,"abstract":"Purpose: To obtain an overview of the surgical practices for the management of intermittent exotropia among experienced surgeons.Methods: We conducted a survey of members of the Korean Association for Pediatric Ophthalmology and Strabismus, who had experience of > 15 years in strabismus surgery, via e-mail. Surgical methods for basic-type intermittent exotropia, angle of deviation for determining the surgical dose, reasons for surgical dose adjustment, and the postoperative target angle of deviation were analyzed.Results: Bilateral lateral rectus recession was preferred over unilateral recession and resection for basic-type intermittent exotropia with or without a dominant eye. The preoperative maximum angle of deviation was preferred for determining the surgical dose by 56% of the participants. Two-thirds of the participants preferred to reduce the surgical dose in specific circumstances, lateral incomitancy being the most common reason. In case of true divergence excess-type intermittent exotropia, 47.7% of the participants reduced the surgical dose. The most preferred target angle of deviation at 1 day postoperatively was 11-15 prism diopter esodeviation, as reported by 40% of the participants.Conclusions: Although experienced surgeons had different surgical preferences for intermittent exotropia, a general trend was found. This survey may be a useful reference for beginners in strabismus surgery.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42835261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Refractive Outcomes of Intraocular Lenses with Different Haptic Designs Following Phacovitrectomy with Gas Tamponade 不同触觉设计的人工晶状体在用气体坦帕钠进行晶状体摘除术后的屈光结果
IF 0.1 Q4 Medicine Pub Date : 2023-08-15 DOI: 10.3341/jkos.2023.64.8.694
S. Lee, Jungmin Lee, S. J. Lee
Purpose: To compare the refractive outcomes of closed C-loop and C-loop intraocular lenses (IOLs) following phacovitrectomy with gas tamponade.Methods: Medical records of 42 patients (43 eyes) who underwent phacovitrectomy with gas tamponade for idiopathic macular holes between January 2021 and June 2022 were retrospectively reviewed. Closed C-loop (26 eyes; Eyelike K-flex Aspheric®, Koryo Eyetech, Seoul, Korea) and C-loop (17 eyes; Tecnis® ZCB00, Johnson & Johnson Vision, Santa Ana, CA, USA) IOLs were surgically implanted. The main outcome measures were postoperative prediction error and absolute error.Results: There was no significant difference in mean absolute error at 5 months postoperatively (0.34 ± 0.24 diopters [D] and 0.30 ± 0.25 D in the closed C-loop and C-loop IOL groups, respectively; p = 0.502). The mean prediction error at 5 months postoperatively also showed no significant difference between the groups (-0.28 ± 0.30 D and -0.16 ± 0.36 D, respectively; p = 0.242). Myopic shift was observed in both groups.Conclusions: There was no significant difference in refractive outcomes between closed C-loop IOLs and C-loop IOLs. A myopic shift was observed in both groups; this should be taken into consideration when calculating IOL power following phacovitrectomy with gas tamponade.
目的:比较C型环和C型环人工晶状体(IOL)在白内障摘除术后的屈光效果。方法:回顾性分析2021年1月至2022年6月期间42例(43眼)因特发性黄斑裂孔接受白内障摘除术并气体填塞的患者的医疗记录。通过手术植入闭合C型环(26只眼睛;Eyelike K-flex Aspharic®,Koryo Eyetech,韩国首尔)和C型环。Tecnis®ZCB00,Johnson&Johnson Vision,Santa Ana,CA,USA)人工晶体。主要观察指标为术后预测误差和绝对误差。结果:术后5个月的平均绝对误差无显著差异(闭合C环和C环IOL组分别为0.34±0.24屈光度[D]和0.30±0.25 D;p=0.502)。术后5月的平均预测误差也无显著差异,组间分别为-0.28±0.30 D和-0.16±0.36 D;p=0.242)在两组中均观察到。结论:闭合C环人工晶状体和C环人工晶体在屈光结果上没有显著差异。两组均观察到近视转移;在用气体填塞进行白内障摘除术后计算IOL功率时,应考虑这一点。
{"title":"Refractive Outcomes of Intraocular Lenses with Different Haptic Designs Following Phacovitrectomy with Gas Tamponade","authors":"S. Lee, Jungmin Lee, S. J. Lee","doi":"10.3341/jkos.2023.64.8.694","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.8.694","url":null,"abstract":"Purpose: To compare the refractive outcomes of closed C-loop and C-loop intraocular lenses (IOLs) following phacovitrectomy with gas tamponade.Methods: Medical records of 42 patients (43 eyes) who underwent phacovitrectomy with gas tamponade for idiopathic macular holes between January 2021 and June 2022 were retrospectively reviewed. Closed C-loop (26 eyes; Eyelike K-flex Aspheric®, Koryo Eyetech, Seoul, Korea) and C-loop (17 eyes; Tecnis® ZCB00, Johnson & Johnson Vision, Santa Ana, CA, USA) IOLs were surgically implanted. The main outcome measures were postoperative prediction error and absolute error.Results: There was no significant difference in mean absolute error at 5 months postoperatively (0.34 ± 0.24 diopters [D] and 0.30 ± 0.25 D in the closed C-loop and C-loop IOL groups, respectively; p = 0.502). The mean prediction error at 5 months postoperatively also showed no significant difference between the groups (-0.28 ± 0.30 D and -0.16 ± 0.36 D, respectively; p = 0.242). Myopic shift was observed in both groups.Conclusions: There was no significant difference in refractive outcomes between closed C-loop IOLs and C-loop IOLs. A myopic shift was observed in both groups; this should be taken into consideration when calculating IOL power following phacovitrectomy with gas tamponade.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45943862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Phacoemulsification Cataract Surgery on the Clinical Outcomes of Advanced Glaucoma Patients 白内障超声乳化手术对晚期青光眼患者临床预后的影响
IF 0.1 Q4 Medicine Pub Date : 2023-08-15 DOI: 10.3341/jkos.2023.64.8.718
B. Han, S. Baek
Purpose: To identify the clinical outcomes of cataract surgery in patients with advanced glaucoma.Methods: A retrospective chart review of open-angle glaucoma patients who underwent cataract surgery and were followed-up for 1 year was conducted. Advanced glaucoma was defined as a mean deviation (MD) < -12 dB on the preoperative visual field test. A group with mild-to-moderate glaucoma (MD ≥ -12 dB) served as the control group. Changes in intraocular pressure (IOP) at 1, 3, 6, and 12 months, and in the postoperative visual acuity (VA) as well as in the visual field indices (MD and the pattern standard deviation), and the number of antiglaucoma medications were compared.Results: Eighty-seven eyes (87 patients) of the advanced group and 109 eyes (109 patients) of the mild-to-moderate group were finally included. From 1 week to 24 months postoperatively, both groups evidenced IOP decreases compared to the preoperative values (both p < 0.05). The IOP spike prevalence was similar in the two groups (11% vs. 13%, p = 0.199). The mean IOP difference between the two groups was not significant at months 1, 3, 6, 12, or 24 postoperatively (all p > 0.05). Both groups evidenced VA improvements at 1 year postoperatively and the visual field (VF) indices did not differ from those before surgery. The numbers of antiglaucoma medications used decreased after surgery, but the decrease was significant only in the advanced glaucoma group (p = 0.030).Conclusions: The advanced and mild-to-moderate glaucoma groups evidenced similar IOP and VF changes after cataract surgery. The VA improved and the number of antiglaucoma medications decreased. Our findings suggest that cataract surgery for patients with advanced glaucoma may afford similar clinical outcomes compared to other less severe glaucoma groups.
目的:探讨晚期青光眼白内障手术的临床效果。方法:对行白内障手术的开角型青光眼患者随访1年的资料进行回顾性分析。晚期青光眼定义为术前视野检查平均偏差(MD) < -12 dB。轻度至中度青光眼(MD≥-12 dB)组作为对照组。比较两组患者1、3、6、12个月眼压(IOP)、术后视力(VA)、视野指数(MD和模式标准差)及抗青光眼药物用量的变化。结果:最终纳入进展组87只眼(87例),轻至中度组109只眼(109例)。术后1周至24个月,两组患者IOP均较术前下降(p < 0.05)。两组的IOP尖峰发生率相似(11%对13%,p = 0.199)。术后1个月、3个月、6个月、12个月、24个月两组平均IOP差异无统计学意义(p < 0.05)。两组术后1年VA均有改善,视野(VF)指数与术前无差异。手术后抗青光眼药物的使用数量减少,但仅在晚期青光眼组有显著性减少(p = 0.030)。结论:晚期和轻中度青光眼组白内障术后IOP和VF变化相似。VA改善,抗青光眼药物的数量减少。我们的研究结果表明,与其他不太严重的青光眼组相比,晚期青光眼患者的白内障手术可能提供相似的临床结果。
{"title":"Effect of Phacoemulsification Cataract Surgery on the Clinical Outcomes of Advanced Glaucoma Patients","authors":"B. Han, S. Baek","doi":"10.3341/jkos.2023.64.8.718","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.8.718","url":null,"abstract":"Purpose: To identify the clinical outcomes of cataract surgery in patients with advanced glaucoma.Methods: A retrospective chart review of open-angle glaucoma patients who underwent cataract surgery and were followed-up for 1 year was conducted. Advanced glaucoma was defined as a mean deviation (MD) < -12 dB on the preoperative visual field test. A group with mild-to-moderate glaucoma (MD ≥ -12 dB) served as the control group. Changes in intraocular pressure (IOP) at 1, 3, 6, and 12 months, and in the postoperative visual acuity (VA) as well as in the visual field indices (MD and the pattern standard deviation), and the number of antiglaucoma medications were compared.Results: Eighty-seven eyes (87 patients) of the advanced group and 109 eyes (109 patients) of the mild-to-moderate group were finally included. From 1 week to 24 months postoperatively, both groups evidenced IOP decreases compared to the preoperative values (both p < 0.05). The IOP spike prevalence was similar in the two groups (11% vs. 13%, p = 0.199). The mean IOP difference between the two groups was not significant at months 1, 3, 6, 12, or 24 postoperatively (all p > 0.05). Both groups evidenced VA improvements at 1 year postoperatively and the visual field (VF) indices did not differ from those before surgery. The numbers of antiglaucoma medications used decreased after surgery, but the decrease was significant only in the advanced glaucoma group (p = 0.030).Conclusions: The advanced and mild-to-moderate glaucoma groups evidenced similar IOP and VF changes after cataract surgery. The VA improved and the number of antiglaucoma medications decreased. Our findings suggest that cataract surgery for patients with advanced glaucoma may afford similar clinical outcomes compared to other less severe glaucoma groups.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42382383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine Learning-based Auto-merge Program for Nine-directional Ocular Photography 基于机器学习的九向眼摄影自动合并程序
IF 0.1 Q4 Medicine Pub Date : 2023-08-15 DOI: 10.3341/jkos.2023.64.8.734
Shin Hyeong Park, Woohyuk Lee, T. Kang, H. Cho, Yongseop Han, Ji Hye Kim
Purpose: This study introduces a new machine learning-based auto-merge program (HydraVersion) that automatically combines multiple ocular photographs into single nine-directional ocular photographs. We compared the accuracy and time required to generate ocular photographs between HydraVersion and PowerPoint.Methods: This was a retrospective study of 2,524 sets of 250 nine-directional ocular photographs (134 patients) between March 2016 and June 2022. The test dataset comprised 74 sets of 728 photographs (38 patients). We measured the time taken to generate nine-directional ocular photographs using HydraVersion and PowerPoint, and compared their accuracy.Results: HydraVersion correctly combined 71 (95.95%) of the 74 sets of nine-directional ocular photographs. The average working time for HydraVersion and PowerPoint was 2.40 ± 0.43 and 255.9 ± 26.7 seconds, respectively; HydraVersion was significantly faster than PowerPoint (p < 0.001).Conclusions: Strabismus and neuro-ophthalmology centers are often unable to combine and store photographs, except those of clinically significant cases, because of a lack of time and manpower. This study demonstrated that HydraVersion may facilitate treatment and research because it can quickly and conveniently generate nine-directional ocular photographs.
目的:本研究介绍了一种新的基于机器学习的自动合并程序(HydraVersion),该程序可以自动将多张眼照片合并为单张九向眼照片。我们比较了HydraVersion和PowerPoint之间生成眼部照片所需的准确性和时间。方法:回顾性分析2016年3月至2022年6月期间,共134例患者共2524组250张九向眼摄影。测试数据集包括74组728张照片(38名患者)。我们测量了使用HydraVersion和PowerPoint生成九向眼照片所需的时间,并比较了它们的准确性。结果:HydraVersion正确组合74组九向眼照片71张(95.95%)。HydraVersion和PowerPoint的平均工作时间分别为2.40±0.43秒和255.9±26.7秒;HydraVersion显著快于PowerPoint (p < 0.001)。结论:由于时间和人力的原因,斜视和神经眼科中心往往无法合并和存储照片,除了那些具有临床意义的病例。本研究表明,HydraVersion可以快速方便地生成九向眼图像,有助于治疗和研究。
{"title":"Machine Learning-based Auto-merge Program for Nine-directional Ocular Photography","authors":"Shin Hyeong Park, Woohyuk Lee, T. Kang, H. Cho, Yongseop Han, Ji Hye Kim","doi":"10.3341/jkos.2023.64.8.734","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.8.734","url":null,"abstract":"Purpose: This study introduces a new machine learning-based auto-merge program (HydraVersion) that automatically combines multiple ocular photographs into single nine-directional ocular photographs. We compared the accuracy and time required to generate ocular photographs between HydraVersion and PowerPoint.Methods: This was a retrospective study of 2,524 sets of 250 nine-directional ocular photographs (134 patients) between March 2016 and June 2022. The test dataset comprised 74 sets of 728 photographs (38 patients). We measured the time taken to generate nine-directional ocular photographs using HydraVersion and PowerPoint, and compared their accuracy.Results: HydraVersion correctly combined 71 (95.95%) of the 74 sets of nine-directional ocular photographs. The average working time for HydraVersion and PowerPoint was 2.40 ± 0.43 and 255.9 ± 26.7 seconds, respectively; HydraVersion was significantly faster than PowerPoint (p < 0.001).Conclusions: Strabismus and neuro-ophthalmology centers are often unable to combine and store photographs, except those of clinically significant cases, because of a lack of time and manpower. This study demonstrated that HydraVersion may facilitate treatment and research because it can quickly and conveniently generate nine-directional ocular photographs.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46224079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of The Korean Ophthalmological Society
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