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Comparison of Anterior Segment Measurements Between Swept-source Optical Coherence Tomography and Schiempflug Coherence Interferometer 横扫光源光学相干断层扫描与施普弗鲁格相干干涉仪的前段测量比较
IF 0.1 Q4 Medicine Pub Date : 2023-12-15 DOI: 10.3341/jkos.2023.64.12.1158
Jiyun Song, Kyung Sun Na
Purpose: To assess the agreement between anterior segment measurements obtained using swept-source optical coherence tomography (Anterion®, Heidelberg Engineering Inc., Heidelberg, Germany) and Scheimpflug partial coherence interferometry (Pentacam HR®, OCULUS, Wetzlar, Germany).Methods: We analyzed the anterior and posterior corneal keratometry, Cartesian astigmatism (J0), oblique astigmatism (J45), anterior chamber depth (ACD), and central corneal thickness (CCT) measurements obtained using the two devices in 65 eyes of 43 subjects.Results: The mean differences between the anterior flat K, anterior steep K, anterior mean K, anterior J0, anterior J45, posterior flat K, posterior steep K, posterior mean K, posterior J0, posterior J45, ACD, and CCT measurements were -0.13 ± 0.34, -0.02 ± 0.33, -0.05 ± 0.31, -0.03 ± 0.39, -0.06 ± 0.35, 0.12 ± 0.09, 0.07 ± 0.08, 0.10 ± 0.06, -0.02 ± 0.14, 0.01 ± 0.16, 0.04 ± 0.06, and -3.51 ± 7.42, respectively. All measurements except posterior J0 and J45 had interclass correlation coefficients greater than 0.75.Conclusions: The mean differences and 95% limits of agreement in this study are consistent with previously reported values. There was a high level of agreement between Anterion® and Pentacam HR®. However, considering the statistically significant differences and limits of agreement for certain measurements, caution should be exercised when assuming interchangeability between these devices.
目的:评估使用扫源光学相干断层扫描(Anterion®,海德堡工程公司,德国海德堡)和Scheimpflug部分相干干涉仪(Pentacam HR®,OCULUS公司,德国韦茨拉尔)进行的前段测量之间的一致性:我们对 43 名受试者的 65 只眼睛使用这两种仪器进行的前后角膜角膜度数、笛卡尔散光(J0)、斜散光(J45)、前房深度(ACD)和中央角膜厚度(CCT)测量结果进行了分析:前平 K 光、前陡 K 光、前平均 K 光、前 J0 光、前 J45 光、后平 K 光、后陡 K 光、后平均 K 光、后 J0 光、后 J45 光、ACD 和 CCT 测量值之间的平均差分别为 -0.13 ± 0.34、-0.02 ± 0.33、-0.05 ± 0.31、-0.03 ± 0.39、-0.06 ± 0.35、0.12 ± 0.09、0.07 ± 0.08、0.10 ± 0.06、-0.02 ± 0.14、0.01 ± 0.16、0.04 ± 0.06 和 -3.51 ± 7.42。除后 J0 和 J45 外,所有测量的类间相关系数均大于 0.75:本研究的平均差和 95% 的一致性限值与之前报道的值一致。Anterion® 和 Pentacam HR® 之间的一致性很高。然而,考虑到某些测量结果在统计学上存在显著差异和一致性限制,在假设这些设备之间具有互换性时应谨慎行事。
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引用次数: 0
Surgical Outcomes in Patients with Intermittent Exotropia with Siblings Who Underwent Surgery by the Same Surgeon 有兄弟姐妹的间歇性外斜患者接受同一外科医生手术的手术结果
IF 0.1 Q4 Medicine Pub Date : 2023-12-15 DOI: 10.3341/jkos.2023.64.12.1245
Chae Won Lim, Won Jae Kim
Purpose: We evaluated surgical outcomes in pediatric patients with intermittent exotropia with and without a family history of exotropia surgery performed by the same surgeon.Methods: We conducted a retrospective review of the medical records of pediatric patients aged ≤ 18 years who underwent surgery for intermittent exotropia between September 2015 and December 2021. We compared surgical outcomes between patients with and without a family history of exotropia surgery performed using 1:1 propensity score matching. A successful surgical outcome was defined as achieving alignment between an exodeviation of 10 prism diopters (PD) and an esodeviation of 4 PD.Results: This study included 60 patients with a family history of exotropia surgery and 60 matched controls with no such history. Notably, the log-rank test revealed no significant differences in surgical outcomes between the two groups (p = 0.622). Furthermore, clinical characteristics, including the onset of exotropia, degree of ocular deviation, and age at surgery, were similar between first- and second-born siblings. Furthermore, no significant differences were observed in surgical outcomes between the two groups (p= 0.540).Conclusions: Patients with a family history of exotropia surgery do not exhibit significantly different surgical outcomes compared to those with no such history. In addition, no significant differences were observed in surgical outcomes between the first- and second-born siblings.
目的:我们评估了间歇性外斜的儿科患者的手术效果,这些患者是否有家族史,是否由同一外科医生进行过外斜手术:我们对2015年9月至2021年12月期间因间歇性外斜接受手术治疗的18岁以下儿童患者的病历进行了回顾性审查。我们采用 1:1 倾向评分匹配法比较了有外斜视手术家族史和无家族史患者的手术结果。成功的手术结果被定义为外差达到10个棱镜屈光度(PD)和内斜达到4个棱镜屈光度(PD)之间的配准:这项研究包括 60 名有外斜视手术家族史的患者和 60 名无此类病史的匹配对照组。值得注意的是,对数秩检验显示两组患者的手术结果无明显差异(P = 0.622)。此外,头胎和二胎兄弟姐妹的临床特征(包括外斜的发病时间、眼球偏斜程度和手术年龄)相似。此外,两组患者的手术结果也无明显差异(P= 0.540):结论:与无外斜视手术家族史的患者相比,有外斜手术家族史的患者的手术效果没有明显差异。结论:有家族外斜手术史的患者与无家族外斜手术史的患者相比,手术效果并无明显差异。此外,第一胎和第二胎兄弟姐妹的手术效果也无明显差异。
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引用次数: 0
Risk Factors of Meibomian Gland Loss in Dry Eye Disease 干眼症患者睑板腺功能丧失的风险因素
IF 0.1 Q4 Medicine Pub Date : 2023-12-15 DOI: 10.3341/jkos.2023.64.12.1152
Ye-Tao Jin, Jong Hyuck Lee, Sun Woong Kim
Purpose: To determine the risk factors of meibomian gland loss in dry eye disease.Methods: The medical charts of 229 dry eye disease patients who had a meibography were retrospectively reviewed. They were divided into 4 groups according to the degree of meibomian gland loss. Telangiectasia and irregularity of eyelid margin, Ocular Surface Disease Index (OSDI), non invasive breakup time (NIBUT), lipid layer thickness (LLT) and tear meniscus height (TMH) were compared. Age, gender, history of eyeline tattoo, history of hypertension, diabetes, dyslipidemia, chemotherapy, radiation therapy, hormone therapy and autoimmune diseases were also investigated to analyze the correlation with the severe meibomian gland loss. Severe meibomian gland loss was defined as loss of more than 75% of the conjunctival area, and risk factors were evaluated using logistic regression analysis.Results: Comparing the four groups divided according to the degree of meibomian gland loss, the group with severe meibomian gland loss was older (p = 0.001), had lower LLT (p < 0.001), had a higher frequency of eyeline tattoos. The ratio of hyperlipidemia (p < 0.001) and chemotherapy (p < 0.001) was also high in the group with severe meibomian gland loss. As a result of multiple logistic regression analysis, age, eyeline tattoo, hyperlipidemia, and chemotherapy were variables that had a significant effect on sever meibomian gland loss. (p < 0.05)Conclusions: Age and history of eyeline tattoo, hyperlipidemia, and chemotherapy are significant variables that cause severe meibomian gland loss in dry eye disease patients. J Korean Ophthalmol Soc 2023;64(12):1152-1157
目的:确定干眼症患者睑板腺脱落的风险因素:回顾性审查了 229 名接受过meibography检查的干眼症患者的病历。根据睑板腺脱落的程度将他们分为 4 组。比较了眼睑边缘的远端扩张和不规则、眼表疾病指数(OSDI)、非侵入性破裂时间(NIBUT)、脂质层厚度(LLT)和泪液半月板高度(TMH)。此外,还调查了年龄、性别、眼线纹身史、高血压史、糖尿病史、血脂异常史、化疗史、放疗史、激素治疗史和自身免疫性疾病史,以分析这些因素与严重睑板腺脱落的相关性。严重睑板腺脱落的定义是结膜脱落面积超过75%,风险因素采用逻辑回归分析进行评估:结果:根据睑板腺脱落程度划分的四组进行比较,严重睑板腺脱落组年龄较大(p = 0.001),LLT较低(p < 0.001),眼线纹身频率较高。高脂血症(p < 0.001)和化疗(p < 0.001)在严重睑板腺脱落组中的比例也较高。多重逻辑回归分析结果显示,年龄、眼线纹身、高脂血症和化疗是对严重睑板腺脱落有显著影响的变量。(P<0.05)结论:年龄、眼线纹身史、高脂血症和化疗是导致干眼症患者睑板腺严重脱落的重要变量。J Korean Ophthalmol Soc 2023;64(12):1152-1157
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引用次数: 0
Comparative Analysis of Contact Lens-related Bacterial Keratitis According to Culture Positivity: A 25-year Retrospective Study 根据培养阳性率比较分析与接触镜相关的细菌性角膜炎:25 年回顾性研究
IF 0.1 Q4 Medicine Pub Date : 2023-12-15 DOI: 10.3341/jkos.2023.64.12.1168
Sunggeun Son, Cheol-Won Moon, C. Cho, Sang-Bumm Lee
Purpose: This study investigated the microbiological profile and clinical characteristics of culture positive (CP) contact lens-related bacterial keratitis (CLBK) and compared them to culture negative (CN) cases.Methods: We retrospectively analyzed 142 CLBK patients hospitalized between January 1998 and December 2022. The CP and CN groups consisted of 79 eyes (100 isolates) and 63 eyes, respectively. We investigated the microbiological profile in the CP group and compared the epidemiology, predisposing factors, clinical characteristics, and treatment outcomes between the CP and CN groups. Poor treatment outcomes were defined as a final best-corrected visual acuity (BCVA) ≤ 0.5, worsened BCVA after treatment, or the need for surgical intervention. We evaluated the risk factors for poor treatment outcomes in the entire cohort through two-proportional Z-test analysis.Results: In CP group, gram-negative bacteria accounted for 85%, and common isolates were Pseudomonas (27%) and Serratia (26%) species. There were significant differences in mean age (27.0 years vs. 33.8 years, p = 0.009) and a history of therapeutic bandage contact lens wear (13.9% vs. 28.6%, p = 0.031) between the CP and CN groups. However, there were no significant differences in symptom duration, prior use of topical antibiotics, sleeping with wearing CL, epithelial defect size, hypopyon, and poor treatment outcomes. Significant risk factors for poor treatment outcomes in the entire group included deep infiltration (Z = 2.88), epithelial healing time ≥ 7 days (Z = 2.30), initial BCVA < 0.1 (Z = 2.20), over date use of contact lens (Z = 2.10), and epithelial defect size ≥ 5 mm2 (Z = 2.05).Conclusions: There were no significant differences in clinical characteristics and treatment outcomes between the CP and CN groups. Poor initial clinical findings and over date use of contact lens were associated with poor treatment outcomes in both groups. J Korean
目的:本研究调查了培养阳性(CP)接触镜相关细菌性角膜炎(CLBK)的微生物概况和临床特征,并与培养阴性(CN)病例进行了比较:我们对 1998 年 1 月至 2022 年 12 月期间住院的 142 名 CLBK 患者进行了回顾性分析。CP组和CN组分别有79只眼睛(100个分离物)和63只眼睛。我们调查了 CP 组的微生物概况,并比较了 CP 组和 CN 组的流行病学、诱发因素、临床特征和治疗效果。治疗效果不佳是指最终最佳矫正视力(BCVA)≤0.5、治疗后BCVA恶化或需要手术干预。我们通过两比例 Z 检验分析评估了整个队列中治疗效果不佳的风险因素:CP组中,革兰氏阴性菌占85%,常见分离菌为假单胞菌(27%)和沙雷氏菌(26%)。CP 组和 CN 组在平均年龄(27.0 岁对 33.8 岁,P = 0.009)和佩戴治疗性绷带隐形眼镜史(13.9% 对 28.6%,P = 0.031)方面存在明显差异。然而,CP 组和 CN 组在症状持续时间、之前使用局部抗生素、戴隐形眼镜睡觉、上皮缺损大小、眼睑下垂和治疗效果不佳方面没有明显差异。全组治疗效果不佳的显著风险因素包括深度浸润(Z = 2.88)、上皮愈合时间≥ 7 天(Z = 2.30)、初始 BCVA < 0.1(Z = 2.20)、过期使用隐形眼镜(Z = 2.10)和上皮缺损面积≥ 5 平方毫米(Z = 2.05):CP组和CN组的临床特征和治疗效果无明显差异。结论:CP 组和 CN 组的临床特征和治疗效果无明显差异,但两组患者的初始临床表现不佳和过期使用隐形眼镜与治疗效果不佳有关。J 韩国人
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引用次数: 0
Long-term Longitudinal Analysis of Subfoveal Choroidal Thickness Following Sulodexide Treatment in Diabetic Retinopathy Patients 糖尿病视网膜病变患者接受舒洛地特治疗后眼底脉络膜厚度的长期纵向分析
IF 0.1 Q4 Medicine Pub Date : 2023-12-15 DOI: 10.3341/jkos.2023.64.12.1208
Chang Min Cha, Jae Wan Lim, C. Kim, Seung Uk Lee, Sang Joon Lee
Purpose: To evaluate the two-year longitudinal changes in subfoveal choroidal thickness (CT) following sulodexide treatment in patients with diabetic retinopathy.Methods: Thirty-eight eyes from patients with diabetic retinopathy, followed for a minimum of two years after sulodexide administration, were included. Subfoveal CT, measured using optical coherence tomography, was analyzed prospectively. Variables including age, sex, duration of diabetes mellitus, HbA1c, blood pressure, sulodexide treatment duration, refractive error, axial length, central macular thickness (CMT), visual acuity, laser photocoagulation, and intravitreal anti-vascular endothelial growth factor injections were evaluated for potential effects on CT. CMT, subfoveal CT, and choroidal vascularity index were compared at baseline and at 6, 12, and 24 months after sulodexide.Results: Of the 38 eyes, 10 belonged to males and 28 to females. The mean data were as follows: age, 67.18 ± 8.87 years; duration of diabetes, 18.11 ± 7.57 years; HbA1c, 8.76 ± 1.60 mmol/L; systolic blood pressure, 134.69 ± 14.68 mmHg; diastolic blood pressure, 73.72 ± 11.90 mmHg; duration of sulodexide, 25.79 ± 3.17 months; refractive error, 0.22 ± 2.19 diopters (D); and axial length, 23.32 ± 0.89 mm. During the observation period, 15 eyes underwent laser photocoagulation and 17 eyes received intravitreal anti-vascular endothelial growth factor injections. The mean subfoveal CT was 216.00 ± 64.23 μm before sulodexide administration and increased to 223.87 ± 62.18 μm, 225.53 ± 62.02 μm, and 225.76 ± 63.62 μm at 6, 12, and 24 months, respectively (p = 0.0377, p = 0.0159, p = 0.0135). The CMT was 318.14 ± 102.28 μm initially and changed to 313.08 ± 77.47 μm, 314.97 ± 88.32 μm, and 320.03 ± 97.36 μm at the aforementioned intervals, with no significant variation (p = 0.904, p = 0.736, p = 0.892).Conclusions: Sulodexide administration led to a significant rise in subfoveal CT over a 2-year follow-up. This change in CT was not mirrored in the CMT.
目的:评估舒洛地特治疗糖尿病视网膜病变患者两年后眼底脉络膜厚度(CT)的纵向变化:方法:纳入糖尿病视网膜病变患者的 38 只眼睛,在服用舒洛地特至少两年后进行随访。使用光学相干断层扫描测量眼底 CT,并对其进行前瞻性分析。评估了年龄、性别、糖尿病持续时间、HbA1c、血压、舒洛地特治疗时间、屈光不正、轴向长度、黄斑中心厚度(CMT)、视力、激光光凝和玻璃体内抗血管内皮生长因子注射等变量对 CT 的潜在影响。比较了基线时以及舒洛地特治疗后 6、12 和 24 个月时的 CMT、眼底 CT 和脉络膜血管指数:38只眼睛中,男性10只,女性28只。平均数据如下:年龄(67.18±8.87)岁;糖尿病病程(18.11±7.57)年;HbA1c(8.76±1.60)mmol/L;收缩压(134.69±14.68)mmHg;舒张压(73.72±11.90)mmHg;服用舒洛地特的时间(25.79±3.17)个月;屈光不正(0.22±2.19)屈光度(D);轴长(23.32±0.89)mm。在观察期间,15 只眼睛接受了激光光凝,17 只眼睛接受了玻璃体内抗血管内皮生长因子注射。服用舒洛地特前,平均眼底 CT 为 216.00 ± 64.23 μm,6、12 和 24 个月时分别增至 223.87 ± 62.18 μm、225.53 ± 62.02 μm、225.76 ± 63.62 μm(p = 0.0377、p = 0.0159、p = 0.0135)。CMT最初为318.14±102.28 μm,在上述时间间隔内分别变为313.08±77.47 μm、314.97±88.32 μm和320.03±97.36 μm,无显著变化(p = 0.904、p = 0.736、p = 0.892):结论:服用舒洛地特会导致眼底 CT 在两年的随访期间显著上升。结论:服用舒洛地特会导致眼底 CT 在 2 年的随访期间明显升高,而 CT 的这种变化并没有反映在 CMT 中。
{"title":"Long-term Longitudinal Analysis of Subfoveal Choroidal Thickness Following Sulodexide Treatment in Diabetic Retinopathy Patients","authors":"Chang Min Cha, Jae Wan Lim, C. Kim, Seung Uk Lee, Sang Joon Lee","doi":"10.3341/jkos.2023.64.12.1208","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.12.1208","url":null,"abstract":"Purpose: To evaluate the two-year longitudinal changes in subfoveal choroidal thickness (CT) following sulodexide treatment in patients with diabetic retinopathy.Methods: Thirty-eight eyes from patients with diabetic retinopathy, followed for a minimum of two years after sulodexide administration, were included. Subfoveal CT, measured using optical coherence tomography, was analyzed prospectively. Variables including age, sex, duration of diabetes mellitus, HbA1c, blood pressure, sulodexide treatment duration, refractive error, axial length, central macular thickness (CMT), visual acuity, laser photocoagulation, and intravitreal anti-vascular endothelial growth factor injections were evaluated for potential effects on CT. CMT, subfoveal CT, and choroidal vascularity index were compared at baseline and at 6, 12, and 24 months after sulodexide.Results: Of the 38 eyes, 10 belonged to males and 28 to females. The mean data were as follows: age, 67.18 ± 8.87 years; duration of diabetes, 18.11 ± 7.57 years; HbA1c, 8.76 ± 1.60 mmol/L; systolic blood pressure, 134.69 ± 14.68 mmHg; diastolic blood pressure, 73.72 ± 11.90 mmHg; duration of sulodexide, 25.79 ± 3.17 months; refractive error, 0.22 ± 2.19 diopters (D); and axial length, 23.32 ± 0.89 mm. During the observation period, 15 eyes underwent laser photocoagulation and 17 eyes received intravitreal anti-vascular endothelial growth factor injections. The mean subfoveal CT was 216.00 ± 64.23 μm before sulodexide administration and increased to 223.87 ± 62.18 μm, 225.53 ± 62.02 μm, and 225.76 ± 63.62 μm at 6, 12, and 24 months, respectively (p = 0.0377, p = 0.0159, p = 0.0135). The CMT was 318.14 ± 102.28 μm initially and changed to 313.08 ± 77.47 μm, 314.97 ± 88.32 μm, and 320.03 ± 97.36 μm at the aforementioned intervals, with no significant variation (p = 0.904, p = 0.736, p = 0.892).Conclusions: Sulodexide administration led to a significant rise in subfoveal CT over a 2-year follow-up. This change in CT was not mirrored in the CMT.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Outcomes of Hammer-Chisel and Drill Techniques to Create Superior Bony Ostium During Endoscopic Dacryocystorhinostomy 内镜下泪囊鼻腔造口术中采用锤凿和钻孔技术创建上骨膜的手术效果
IF 0.1 Q4 Medicine Pub Date : 2023-12-15 DOI: 10.3341/jkos.2023.64.12.1127
Hye Jin Lee, Jun Ho Oh, Yong Koo Kang, Dai Woo Kim, Byeong Jae Son
Purpose: We introduce a “cold steel” hammer-chisel technique for endoscopic dacryocystorhinostomy, then compare postoperative outcomes between this technique and a drill technique.Methods: This study included 191 patients (297 eyes) with nasolacrimal duct stenoses or obstructions who underwent endoscopic dacryocystorhinostomy using the hammer-chisel or drill technique. Surgical outcomes were compared via follow-up screening for epiphora and anatomical complications such as granuloma and fibrous membrane formation, canalicular obstruction, and synechiae.Results: Postoperative anatomical complications occurred in 29 eyes (18.6%) in the hammer-chisel group and 51 eyes (36.2%) in the drill group (p = 0.001). The anatomical failure rate was higher in the drill group [28 eyes (19.9%)] than in the hammer-chisel group [18 eyes (11.5%); p = 0.038]. Functional failure was observed in 13 eyes (8.3%) in the hammer-chisel group and 13 eyes (9.2%) in the drill group (p = 0.787). The mean operation time was significantly longer in the drill group (35.5 ± 10.4 minutes vs. 25.4 ± 9.1 minutes) (p < 0.001).Conclusions: During endoscopic dacryocystorhinostomy, osteotomy with a hammer-chisel is more successful and leads to fewer complications than osteotomy with a drill.
目的:我们介绍了一种用于内窥镜泪囊鼻腔吻合术的 "冷钢 "锤凿技术,然后比较了这种技术和钻孔技术的术后效果:这项研究纳入了 191 位鼻泪管狭窄或阻塞的患者(297 只眼),他们都使用锤凿或钻孔技术接受了内窥镜泪囊鼻腔吻合术。通过随访筛查眼外窥和解剖并发症(如肉芽肿和纤维膜形成、管腔阻塞和虹膜瘤),对手术结果进行了比较:锤凿组有 29 只眼睛(18.6%)出现术后解剖并发症,钻孔组有 51 只眼睛(36.2%)出现术后解剖并发症(P = 0.001)。钻孔组解剖失败率[28 眼(19.9%)]高于锤凿组[18 眼(11.5%);P = 0.038]。锤凿组有 13 只眼睛(8.3%)功能失败,钻孔组有 13 只眼睛(9.2%)功能失败(p = 0.787)。钻孔组的平均手术时间明显更长(35.5 ± 10.4 分钟对 25.4 ± 9.1 分钟)(p < 0.001):在内窥镜下进行泪囊鼻腔造口术时,使用锤凿截骨比使用钻头截骨更成功,并发症更少。
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引用次数: 0
Epidemiology and Clinical Features Analysis of Orbital and Adnexal Lymphoma in the Western Area of Gyeongsangnam-do 庆尚南道西部地区眼眶和附件淋巴瘤的流行病学和临床特征分析
IF 0.1 Q4 Medicine Pub Date : 2023-12-15 DOI: 10.3341/jkos.2023.64.12.1136
I. Jeong, Seong-Jae Kim, S. Seo
Purpose: We compared the epidemiology and clinical features of patients with orbital and adnexal lymphoma in western Gyeongsangnam-do with those reported previously, domestically and internationally.Methods: Of the 25 patients diagnosed with lymphoproliferative disorder, a retrospective analysis was conducted on 21 patients with orbital and adnexal lymphoma between January 2010 and December 2021.Results: In total, 21 patients were diagnosed with orbital and adnexal lymphoma, with an average annual incidence rate of 0.18 per 100,000 people, exceeding the national average in Korea. The median age of the patients was 57 years and the ratio of 1.1 to 1. The most common presenting symptoms included proptosis, conjunctival mass, conjunctival injection, eyelid swelling and epiphora. Primary and metastatic lesions accounted for 85.7% and 14.3% of cases, respectively. Histologically, the most common subtype was extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (90.4%). Furthermore, diffuse large B-cell lymphoma and NK/T-cell lymphoma of T-cell origin each accounted for 4.8% of cases.Conclusions: The reported incidence rate in the present study exceeded the national average in Korea. However, no significant differences were observed in clinical symptoms, primary and metastatic lesions, histological classification, or post-treatment effects compared to findings from domestic and international studies.
目的:将庆尚南道西部地区眼眶和附件淋巴瘤患者的流行病学和临床特征与此前国内外报道的情况进行比较:在25名被诊断为淋巴组织增生性疾病的患者中,对2010年1月至2021年12月期间的21名眼眶和附件淋巴瘤患者进行了回顾性分析:共有21名患者被确诊为眼眶和附件淋巴瘤,年平均发病率为每10万人中0.18例,超过韩国全国平均水平。最常见的症状包括眼球突出、结膜肿块、结膜注射、眼睑肿胀和眼睑外翻。原发性和转移性病变分别占 85.7% 和 14.3%。组织学上,最常见的亚型是粘膜相关淋巴组织的结节外边缘区B细胞淋巴瘤(90.4%)。此外,弥漫大B细胞淋巴瘤和T细胞来源的NK/T细胞淋巴瘤各占4.8%:结论:本研究报告的发病率超过了韩国全国的平均水平。结论:本研究报告的发病率超过了韩国全国的平均水平,但与国内外的研究结果相比,在临床症状、原发和转移病灶、组织学分类或治疗后效果等方面未发现明显差异。
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引用次数: 0
Two Cases of Sudden Intraocular Pressure Elevation in Children after Steroid Treatment 两例类固醇治疗后眼压突然升高的儿童病例
IF 0.1 Q4 Medicine Pub Date : 2023-12-15 DOI: 10.3341/jkos.2023.64.12.1268
Minjeong Kim, K. Kim, J. Jeong, Nam Ju Moon, Y. Chun
Purpose: We report two cases of sudden intraocular pressure (IOP) elevation in children after steroid treatment.Case summary: (Case 1) An 8-year-old boy visited the hospital with vomiting and headache that had begun 3 days after application of dexamethasone eyedrops. IOPs were 55 and 62 mmHg in the right and left eyes, respectively; both anterior chambers were normal. The eyedrops were stopped and timolol/dorzolamide was applied twice daily. After intravenous mannitol injection, the IOPs of both eyes decreased to 18 mmHg within 24 hours. (Case 2) A 10-year-old boy diagnosed with coronavirus disease 2019 three days prior had been prescribed methylprednisolone 4 mg twice daily; he visited the hospital with headache, eye pain, and decreased vision that began 1 day after medication. IOPs were 41 and 54 mmHg in the right and left eyes, respectively; both anterior chambers were normal. After drug discontinuation, timolol/dorzolamide, brimonidine, and latanoprost eyedrops were applied. Subsequently, after intravenous mannitol injection, the IOPs decreased within 24 hours to 7 and 16 mmHg in the right and left eyes, respectively; they remained stable. However, thinning was observed in the retinal nerve fiber and ganglion cell-inner plexiform layer.Conclusions: Children can develop rapid IOP elevation after even 1 day of steroid use; residual structural damage may be present, despite prompt treatment. Clinicians must closely monitor such patients for atypical IOP elevation.
目的:我们报告了两例儿童在接受类固醇治疗后眼压突然升高的病例。病例摘要:(病例 1)一名 8 岁男孩在使用地塞米松眼药水 3 天后因呕吐和头痛到医院就诊。右眼和左眼的眼压分别为 55 和 62 毫米汞柱,两个前房均正常。停用眼药水后,每天使用两次噻吗洛尔/度冷丁。静脉注射甘露醇后,双眼的眼压在 24 小时内降至 18 毫米汞柱。(病例 2)一名 10 岁男孩在 3 天前被诊断为 2019 年冠状病毒病,医生给他开了甲基强的松龙 4 毫克,每天两次。右眼和左眼的眼压分别为 41 毫米汞柱和 54 毫米汞柱,两个前房均正常。停药后,使用了噻吗洛尔/多佐胺、溴莫尼丁和拉坦前列素眼药水。随后,在静脉注射甘露醇后,右眼和左眼的眼压在 24 小时内分别降至 7 毫米汞柱和 16 毫米汞柱,并保持稳定。然而,在视网膜神经纤维层和神经节细胞内丛状层观察到变薄:结论:使用类固醇一天后,儿童的眼压就会迅速升高;尽管治疗及时,但仍可能存在残余的结构性损伤。临床医生必须密切监测此类患者的非典型眼压升高。
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引用次数: 0
Association Between Tear Osmolarity and Dry Eye Signs in Patients with Obstructive Meibomian Gland Dysfunction 泪液渗透压与睑板腺功能障碍患者干眼症状之间的关系
IF 0.1 Q4 Medicine Pub Date : 2023-12-15 DOI: 10.3341/jkos.2023.64.12.1183
Han Sol Choi, Si Hyung Lee
Purpose: To explore the correlations between tear osmolarity, as measured using I-PEN® (I-MED Pharma, Inc., Dollard-des-Ormeaux, QC, Canada), and various dry eye indicators, including the Schirmer test, tear break-up time (TBUT), Oxford scale, and Ocular Surface Disease Index (OSDI), in patients with obstructive meibomian gland dysfunction (MGD).Methods: The medical records of 44 cases of obstructive MGD were reviewed. Tear osmolarity was obtained using I-PEN® (I-MED Pharma, Inc.). The TBUT, Schirmer test, Oxford scale, OSDI, and MGD grade were used to assess the cases, and their correlations with tear osmolarity were analyzed.Results: Spearman and Pearson correlation analyses showed a significant correlation between tear osmolarity and MGD grade (p < 0.001) and OSDI (p = 0.005). However, the results of the TBUT, Schirmer test, and Oxford scale were not significantly related to tear osmolarity. The patients were divided according to MGD severity into those with MGD grades ≤ 2 and those with MGD grades ≥ 3. Tear osmolarity (p < 0.001) and OSDI (p = 0.014) showed significant differences between the two groups.Conclusions: In patients with obstructive MGD, tear osmolarity, assessed using I-PEN® (I-MED Pharma, Inc.), is significantly correlated with MGD grade and OSDI.
目的:探讨阻塞性睑板腺功能障碍(MGD)患者使用 I-PEN® (I-MED Pharma, Inc., Dollard-des-Ormeaux, QC, Canada)测量的泪液渗透压与各种干眼指标(包括 Schirmer 试验、泪液破裂时间(TBUT)、牛津量表和眼表疾病指数(OSDI))之间的相关性:方法:回顾 44 例阻塞性睑板腺功能障碍患者的病历。使用 I-PEN® (I-MED Pharma, Inc.) 采集泪液渗透压。采用 TBUT、Schirmer 试验、牛津量表、OSDI 和 MGD 分级对病例进行评估,并分析其与泪液渗透压的相关性:结果:Spearman 和 Pearson 相关性分析表明,泪液渗透压与 MGD 等级(p < 0.001)和 OSDI(p = 0.005)之间存在显著相关性。然而,TBUT、Schirmer 试验和牛津量表的结果与泪渗透压无明显关系。根据 MGD 的严重程度,将患者分为 MGD 等级≤2 级和 MGD 等级≥3 级。两组患者的泪液渗透压(p < 0.001)和OSDI(p = 0.014)有显著差异:在阻塞性 MGD 患者中,使用 I-PEN® (I-MED Pharma, Inc.) 评估的泪液渗透压与 MGD 分级和 OSDI 显著相关。
{"title":"Association Between Tear Osmolarity and Dry Eye Signs in Patients with Obstructive Meibomian Gland Dysfunction","authors":"Han Sol Choi, Si Hyung Lee","doi":"10.3341/jkos.2023.64.12.1183","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.12.1183","url":null,"abstract":"Purpose: To explore the correlations between tear osmolarity, as measured using I-PEN® (I-MED Pharma, Inc., Dollard-des-Ormeaux, QC, Canada), and various dry eye indicators, including the Schirmer test, tear break-up time (TBUT), Oxford scale, and Ocular Surface Disease Index (OSDI), in patients with obstructive meibomian gland dysfunction (MGD).Methods: The medical records of 44 cases of obstructive MGD were reviewed. Tear osmolarity was obtained using I-PEN® (I-MED Pharma, Inc.). The TBUT, Schirmer test, Oxford scale, OSDI, and MGD grade were used to assess the cases, and their correlations with tear osmolarity were analyzed.Results: Spearman and Pearson correlation analyses showed a significant correlation between tear osmolarity and MGD grade (p < 0.001) and OSDI (p = 0.005). However, the results of the TBUT, Schirmer test, and Oxford scale were not significantly related to tear osmolarity. The patients were divided according to MGD severity into those with MGD grades ≤ 2 and those with MGD grades ≥ 3. Tear osmolarity (p < 0.001) and OSDI (p = 0.014) showed significant differences between the two groups.Conclusions: In patients with obstructive MGD, tear osmolarity, assessed using I-PEN® (I-MED Pharma, Inc.), is significantly correlated with MGD grade and OSDI.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138997074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retinal Changes in a Patient with a Traumatic Orbital Subperiosteal Hematoma and Superior Ophthalmic Vein Compression 外伤性眼眶骨膜下血肿和眼上静脉压迫症患者的视网膜变化
IF 0.1 Q4 Medicine Pub Date : 2023-12-15 DOI: 10.3341/jkos.2023.64.12.1252
Gwon Hui Jo, Gye-sang Lim, Kyung Tae Kim, Seong Eun Lee, Eoi Jong Seo
Purpose: We describe a case with retinal alterations similar to those of nonischemic central retinal vein occlusion, but also with superior ophthalmic vein compression attributable to a traumatic, subperiosteal orbital hematoma.Case summary: A 13-year-old male presented with left periorbital edema, a decrease in vision, and diplopia after blunt periorbital trauma. In ophthalmological evaluations, the best-corrected visual acuity (BCVA) was 0.4 (20/50) and a severe supraduction limitation was apparent (grade -4). Fundus examination revealed optic disc swelling, retinal vein dilation/tortuosity, and an arteriovenous transit time delay of 26s. Fluorescein angiography evidenced optic disc leakage. Ocular sonography and orbital magnetic resonance imaging revealed a superior subperiosteal hematoma in the left orbit accompanied by superior ophthalmic vein compression. We scheduled emergency hematoma evacuation. One month later, the BCVA had increased to 1.0 (20/20) and ocular movement was no longer limited. Orbital computed tomography showed that the superior ophthalmic vein compression had resolved and that the abnormalities observed in the initial fundus examination and fluorescein angiography had improved.Conclusions: Retinal changes that resemble nonischemic central retinal vein occlusion including retinal venous dilation and tortuosity may develop after a traumatic, orbital subperiosteal hematoma. Compressive obstruction of the superior ophthalmic vein may then be in play. Early surgical intervention featuring hematoma evacuation may prevent irreversible visual deterioration.
目的:我们描述了一例视网膜改变类似于非缺血性视网膜中央静脉闭塞的病例,但也有因外伤性骨膜下眶血肿导致的眼上静脉受压病例。病例摘要:一名 13 岁的男性在钝性眶周外伤后出现左眶周水肿、视力下降和复视。在眼科检查中,最佳矫正视力(BCVA)为 0.4(20/50),且明显存在严重的上睑下垂(-4 级)。眼底检查显示视盘肿胀,视网膜静脉扩张/扭曲,动静脉通过时间延迟 26 秒。荧光素血管造影显示视盘渗漏。眼部超声波检查和眼眶磁共振成像显示,左眼眶内有上骨膜下血肿,并伴有眼上静脉压迫。我们安排了紧急血肿清除术。一个月后,BCVA 增至 1.0(20/20),眼球活动不再受限。眼眶计算机断层扫描显示,眼上静脉压迫症状已经缓解,最初眼底检查和荧光素血管造影观察到的异常情况也有所改善:结论:外伤性眼眶骨膜下血肿后可能会出现类似非缺血性视网膜中央静脉闭塞的视网膜变化,包括视网膜静脉扩张和迂曲。这时,眼上静脉的压迫性阻塞可能会发挥作用。以清除血肿为特征的早期手术干预可防止不可逆转的视力恶化。
{"title":"Retinal Changes in a Patient with a Traumatic Orbital Subperiosteal Hematoma and Superior Ophthalmic Vein Compression","authors":"Gwon Hui Jo, Gye-sang Lim, Kyung Tae Kim, Seong Eun Lee, Eoi Jong Seo","doi":"10.3341/jkos.2023.64.12.1252","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.12.1252","url":null,"abstract":"Purpose: We describe a case with retinal alterations similar to those of nonischemic central retinal vein occlusion, but also with superior ophthalmic vein compression attributable to a traumatic, subperiosteal orbital hematoma.Case summary: A 13-year-old male presented with left periorbital edema, a decrease in vision, and diplopia after blunt periorbital trauma. In ophthalmological evaluations, the best-corrected visual acuity (BCVA) was 0.4 (20/50) and a severe supraduction limitation was apparent (grade -4). Fundus examination revealed optic disc swelling, retinal vein dilation/tortuosity, and an arteriovenous transit time delay of 26s. Fluorescein angiography evidenced optic disc leakage. Ocular sonography and orbital magnetic resonance imaging revealed a superior subperiosteal hematoma in the left orbit accompanied by superior ophthalmic vein compression. We scheduled emergency hematoma evacuation. One month later, the BCVA had increased to 1.0 (20/20) and ocular movement was no longer limited. Orbital computed tomography showed that the superior ophthalmic vein compression had resolved and that the abnormalities observed in the initial fundus examination and fluorescein angiography had improved.Conclusions: Retinal changes that resemble nonischemic central retinal vein occlusion including retinal venous dilation and tortuosity may develop after a traumatic, orbital subperiosteal hematoma. Compressive obstruction of the superior ophthalmic vein may then be in play. Early surgical intervention featuring hematoma evacuation may prevent irreversible visual deterioration.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138997639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of The Korean Ophthalmological Society
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