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Clinical Outcomes after Exchange of Diffractive Multifocal Intraocular Lenses with Monofocal Intraocular Lenses 衍射多焦人工晶状体与单焦人工晶状体置换后的临床疗效
Q4 OPHTHALMOLOGY Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.768
Sang Eun Im, Jungmin Lee, Sung Jin Lee
Purpose: To determine the clinical outcomes after exchange of diffractive multifocal intraocular lenses (IOLs) with monofocal IOLs for patients who complained of dysphotopsia after cataract surgery.Methods: We exchanged the IOLs of patients who visited our clinic complaining that dysphotopsia had not improved after they underwent phacoemulsification and diffractive multifocal IOL implants in local eye clinics. We evaluated the corrected distance visual acuity (CDVA) before and after operation, the type of preoperative dysphotopsia, postoperative dysphotopsia status, patient satisfaction, and all complications.Results: We enrolled 35 eyes of 27 patients and observed them for 5.7 ± 3.6 months. After 1 month, the CDVA significantly (p < 0.001) improved from 0.131 ± 0.131 logarithm of the minimal angle resolution (logMAR) preoperatively to 0.0328 ± 0.0900 logMAR postoperatively. Patient satisfaction graded on a scale from 1 (very dissatisfied) to 5 (excellent) significantly (p < 0.001) increased from 1.17 ± 0.382 preoperatively to 4.09 ± 0.818 postoperatively. No vision-threatening complications developed. Postoperative cystoid macular edema developed in one eye but resolved after intravitreal bevacizumab (Avastin®, Genetech, Inc, San Francisco, CA, USA) injections.Conclusions: IOL exchange surgery relatively safely improves the vision of patients suffering from dysphotopsia attributable to the characteristics of diffractive multifocal IOLs.
目的:探讨单焦人工晶状体与衍射多焦人工晶状体置换后的临床效果。方法:对在当地眼科诊所行超声乳化术和衍射多焦人工晶体植入术后视力不良未得到改善的患者进行人工晶体置换。我们评估术前、术后矫正距离视力(CDVA)、术前移位移位类型、术后移位移位情况、患者满意度及所有并发症。结果:纳入27例患者35只眼,观察5.7±3.6个月。1个月后,CDVA显著(<i>p</i>& lt;最小角度分辨率(logMAR)由术前的0.131±0.131对数提高到术后的0.0328±0.0900对数。患者满意度从1(非常不满意)到5(极好)显著(<i>p</i>& lt;0.001),由术前的1.17±0.382增至术后的4.09±0.818。没有出现威胁视力的并发症。术后单眼出现囊样黄斑水肿,但玻璃体内注射贝伐单抗(Avastin<sup>®</sup>, Genetech, Inc, San Francisco, CA, USA)后消退。结论:由于衍射型多焦IOL的特点,人工晶状体置换术可以相对安全地改善患者的视力。
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引用次数: 0
Neovascular Glaucoma as the Initial Presentation of Ocular Tuberculosis 新血管性青光眼是眼结核的初始表现
Q4 OPHTHALMOLOGY Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.859
Yongwun Cho, Jeongwoo Kwon, Jin-Seok Seo, Gyu-Nam Kim, Woong-Sun Yoo, In Young Chung
Purpose: To report a case of ocular tuberculosis that first manifested as neovascular glaucoma.Case summary: A 76-year-old male visited our hospital complaining of decreased visual acuity in the left eye. He had undergone tuberculosis treatment 1 year prior, and had been cured. At the time of his visit, decreased visual acuity, increased intraocular pressure, and iris neovascularization were observed in the left eye. He was diagnosed with neovascular glaucoma and was started on treatment to lower the intraocular pressure. At the time of the visit, we also noticed vitreous opacity in both eyes. The patient did not attend his scheduled follow-up visit, but returned 2 months later complaining of decreased visual acuity in both eyes. The vitreous opacity in the retinae of both eyes had become aggravated. Diagnostic vitrectomy was performed on both eyes, and multiple yellowish-white circular lesions were observed throughout the retinae. Systemic abnormalities were suspected, and thus additional tests were performed. Bronchoalveolar lavage fluid analysis revealed recurrence of pulmonary tuberculosis, and tuberculosis treatment was recommenced. Temporary increases in ocular inflammation and deterioration were observed but improved after the addition of systemic steroids. The patient has been under observation without recurrence for about 1 year.Conclusions: Ocular tuberculosis can be expressed in the form of neovascular glaucoma, so ocular tuberculosis should be suspected if there is a history of tuberculosis and abnormal retinal findings.
目的:报告一例以新生血管性青光眼为首发表现的眼结核。病例总结:一名76岁男性患者就诊,主诉左眼视力下降。他在一年前接受过肺结核治疗,现已痊愈。就诊时,左眼视力下降,眼压升高,虹膜新生血管形成。他被诊断为新生血管性青光眼,并开始接受降低眼压的治疗。在就诊时,我们还注意到两只眼睛的玻璃体浑浊。患者没有参加预定的随访,但2个月后返回,主诉双眼视力下降。双眼视网膜玻璃体混浊加重。诊断性玻璃体切除双眼,视网膜可见多个黄白色圆形病变。怀疑全身性异常,因此进行了额外的检查。支气管肺泡灌洗液分析显示肺结核复发,并重新开始肺结核治疗。观察到眼部炎症和恶化的暂时增加,但在添加全身类固醇后得到改善。患者观察1年无复发。结论:眼结核可表现为新生血管性青光眼,有结核病史及视网膜异常表现者应怀疑眼结核。
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引用次数: 0
Trichofolliculoma in the Medial Canthal Area 内眦区毛囊瘤
Q4 OPHTHALMOLOGY Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.851
In Seok Jeong, Seong Jae Kim, Seong Wook Seo
Purpose: We report a case of trichofolliculoma located in the medial canthal area that was initially clinically suspected to be basal cell carcinoma.Case summary: A 93-year-old female patient presented to our hospital with a 1.2 × 1.4 cm mass in the right medial canthal area that had been present for 8 months. She had experienced continuous bleeding-like secretions during this time, leading to suspicion of basal cell carcinoma due to the absence of hair and a painless central ulcer lesion. Excision and biopsy were performed; the biopsy results revealed trichofolliculoma. The patient underwent complete resection and has remained recurrence-free for 6 months with regular follow-up observations.Conclusions: Trichofolliculoma is a rare follicular hamartoma characterized by a nodule with dilated pores and dense hair in the center. Given its clinical similarity to benign and malignant tumors, such as basal cell carcinoma and squamous cell carcinoma, it is essential to differentiate this condition through excision and biopsy.
目的:我们报告一例位于内侧眦区域的毛滤泡瘤,最初临床怀疑为基底细胞癌。病例总结:一名93岁女性患者因右侧内侧眦区1.2 × 1.4 cm肿物8个月来我院就诊。在此期间,患者出现持续的出血样分泌物,因无毛发和无痛性中枢性溃疡病变,怀疑为基底细胞癌。行切除和活检;活检结果显示毛囊瘤。患者接受了完全切除,并定期随访观察,6个月无复发。结论:毛囊瘤是一种罕见的毛囊错构瘤,其特征是结节状的毛孔扩张,中间有浓密的毛发。鉴于其与基底细胞癌、鳞状细胞癌等良恶性肿瘤的临床相似性,有必要通过手术切除和活检进行鉴别。
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引用次数: 0
Tear Film and Drainage after Selective Punctal Occlusion Using Polydioxanone Plugs in Dry Eye Patients 干眼症患者选择性点阻断后泪膜及泪液引流
Q4 OPHTHALMOLOGY Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.759
Sung Eun Im, Hee Chul Lee, Sang Soo Kim
Purpose: To assess changes in the tear film and delayed tear drainage after upper or lower, or combined upper and lower, punctal occlusion using dissolvable polydioxanone plugs in patients with dry eye.Methods: In total, 40 dry eye patients (80 eyes) were enrolled: four groups of 10 (20 eyes) with no, lower, upper, and lower and upper punctal occlusions. Dissolvable polydioxanone plugs were placed. The tear break-up time (tBUT) and the tear meniscus height (TMH) were measured, and the Schirmer I test and dye disappearance test (DDT) were performed at baseline and 2 weeks after the procedure.Results: Compared to the control group, all three test groups exhibited significant changes in the tBUT, the DDT test, and the TMH after polydioxanone plug placement (all p < 0.05). The group with both upper and lower punctal occlusions exhibited more delayed tear drainage than the other test groups. A lower punctal occlusion significantly delayed tear drainage to a greater extent than did an upper punctal occlusion (p = 0.010).Conclusions: In dry eye patients, a polydioxanone plug improved the tBUT and TMH, and the DDT score. The tear drainage delay increased in the order: both, lower, and upper punctal occlusion(s).
目的:评价干眼症患者使用可溶解聚二恶酮眼塞进行上、下点或上下点联合封堵后泪液膜的变化和延迟泪液引流。方法:共40例(80眼)干眼症患者分为4组,每组10例(20眼),无、下、上、下、上点闭塞。放置可溶解的聚二氧环酮塞。测定撕裂破裂时间(tBUT)和撕裂半月板高度(TMH),并在基线和术后2周进行Schirmer I试验和染料消失试验(DDT)。结果:与对照组相比,所有三个试验组在tBUT、DDT试验和聚二氧环酮塞置入后的TMH均有显著变化(均为<i>p</i>& lt;0.05)。上、下点闭塞组比其他试验组有更多的延迟泪液排出。与上点阻塞相比,下点阻塞显著延迟泪滴引流(<i>p</i>= 0.010)。结论:在干眼症患者中,聚二恶酮塞可改善tBUT和TMH,以及DDT评分。泪液引流延迟的顺序依次为:下、上点闭塞。
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引用次数: 0
Unilateral Eyelid Swelling Secondary to Local Palpebral Conjunctival Amyloidosis in a Young Patient 单侧眼睑肿胀继发于局部睑结膜淀粉样变1例
Q4 OPHTHALMOLOGY Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.854
Haeeun Shin, Youjeong Seo, Ji Won Jung
Purpose: We report a young patient with unilateral eyelid swelling secondary to local, palpebral conjunctival amyloidosis.Case summary: A 31-year-old male was referred with a 6-month history of mild, right upper eyelid swelling but without redness or tenderness. Slit-lamp examination revealed a diffuse hemorrhagic papilliform lesion on the right upper palpebral conjunctiva, this raised a suspicion of giant papillary conjunctivitis. As the lesion was unilateral, there was no history of allergic disease or contact lens use, and the lesion was refractory to topical anti-inflammatory treatment so, excisional biopsy of the right upper palpebral conjunctiva was performed. During the operation, the papilliform lesion was removed, it peeled off on the blade. After surgery, the eyelid swelling improved. Histopathological examination revealed an eosinophilic amorphous deposit consistent with amyloidosis. Further evaluation ruled out systemic amyloidosis; there were no abnormal findings. Thus, we diagnosed primary localized amyloidosis of the palpebral conjunctiva. At the 1-year follow-up, no recurrence was detected.Conclusions: Although primary localized amyloidosis of the palpebral conjunctiva is rare, this should be considered if chronic eyelid swelling accompanied by another conjunctival lesion such as giant papillary conjunctivitis is encountered.
目的:我们报告一个年轻的患者单侧眼睑肿胀继发于局部,眼睑结膜淀粉样变。病例总结:31岁男性,有6个月轻度右上眼睑肿胀史,但无红肿或压痛。裂隙灯检查显示右上睑结膜弥漫性出血性乳头状病变,怀疑为巨大乳头状结膜炎。由于病变为单侧,无过敏史,无隐形眼镜使用史,且局部抗炎治疗难治,故行右侧上睑结膜切除活检。在手术过程中,乳头状病变被移除,它在刀片上脱落。手术后,眼睑肿胀有所改善。组织病理学检查显示嗜酸性无定形沉积物与淀粉样变性一致。进一步的评估排除了系统性淀粉样变性;未见异常。因此,我们诊断原发性局限性睑结膜淀粉样变性。随访1年,未见复发。结论:虽然原发性睑结膜局限性淀粉样变性罕见,但如果遇到慢性眼睑肿胀并伴有其他结膜病变,如巨大乳头状结膜炎,则应考虑这种情况。
{"title":"Unilateral Eyelid Swelling Secondary to Local Palpebral Conjunctival Amyloidosis in a Young Patient","authors":"Haeeun Shin, Youjeong Seo, Ji Won Jung","doi":"10.3341/jkos.2023.64.9.854","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.9.854","url":null,"abstract":"Purpose: We report a young patient with unilateral eyelid swelling secondary to local, palpebral conjunctival amyloidosis.Case summary: A 31-year-old male was referred with a 6-month history of mild, right upper eyelid swelling but without redness or tenderness. Slit-lamp examination revealed a diffuse hemorrhagic papilliform lesion on the right upper palpebral conjunctiva, this raised a suspicion of giant papillary conjunctivitis. As the lesion was unilateral, there was no history of allergic disease or contact lens use, and the lesion was refractory to topical anti-inflammatory treatment so, excisional biopsy of the right upper palpebral conjunctiva was performed. During the operation, the papilliform lesion was removed, it peeled off on the blade. After surgery, the eyelid swelling improved. Histopathological examination revealed an eosinophilic amorphous deposit consistent with amyloidosis. Further evaluation ruled out systemic amyloidosis; there were no abnormal findings. Thus, we diagnosed primary localized amyloidosis of the palpebral conjunctiva. At the 1-year follow-up, no recurrence was detected.Conclusions: Although primary localized amyloidosis of the palpebral conjunctiva is rare, this should be considered if chronic eyelid swelling accompanied by another conjunctival lesion such as giant papillary conjunctivitis is encountered.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135355088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corneal Topographic Changes after Botulinum Toxin-A Injection in Patients with Essential Blepharospasm 原发性眼睑痉挛患者注射a型肉毒杆菌毒素后角膜地形图的改变
Q4 OPHTHALMOLOGY Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.845
Sangyoon Kim, Jung Hyo Ahn
Purpose: To compare the corneal topographic change before and after botulinum toxin A injection in patients with essential blepharospasm.Methods: From September 2015 to December 2020, we enrolled total 20 patients, 40 eyes diagnosed with essential blepharospasm. We estimated the corneal refractive power and astigmatism before and after Nabota® (Daewoong Co. Ltd, Seoul, Korea) botulinum toxin injection at 1 and 3 months using iTrace® Topography (Software version 4.2.1., Tracey technology Inc., Houston, TX, USA). Corneal refractive power was analyzed in superior, inferior, nasal and temporal location at 1 mm, 3 mm zone. Also, steep and flat keratometry, astigmatism was measured by topography.Results: Corneal refractive power showed significant difference in superior and inferior location of 1 mm zone at 1 month after botulinum toxin injection (p = 0.038, p = 0.042). There was no significant difference in all four locations of 3 mm zone. At 1 month after toxin injection, steep keratometry was only significant reduced (p = 0.046) and with-the-rule astigmatism was shifted to against-the-rule astigmatism. At 3 months after toxin injection, keratometry and astigmatism was resolved to before toxin injection.Conclusions: At 1 month after Nabota® (Daewoong Co. Ltd) botulinum toxin injection, corneal refractive power at vertical axis was flattened and steep keratometry was significantly reduced. At 3 months after toxin injection, corneal topographic change was changed to before toxin injection.
目的:比较原发性眼睑痉挛患者注射A型肉毒杆菌毒素前后角膜地形图的变化。方法:2015年9月至2020年12月,共入组20例患者,40只眼诊断为原发性眼睑痉挛。我们估计了nababta <sup>®</sup>前后角膜屈光度和散光。(Daewoong Co. Ltd, Seoul, Korea) 1个月和3个月时使用iTrace<sup>®</sup>地形(软件版本4.2.1。, Tracey technology Inc., Houston, TX, USA)。分析角膜上、下、鼻、颞部1mm、3mm区域的屈光度。同时,用地形法测量陡角、平角、散光。结果:注射肉毒毒素1个月后,角膜屈光度上、下1mm区有显著性差异(<i>p</i>= 0.038, <i> </i>= 0.042)。在3 mm区域的4个位置,无显著性差异。注射毒素1个月后,陡角测深仅显著降低(<i>p</i>= 0.046),顺势散光变为反顺势散光。注射后3个月,角膜光度和散光恢复到注射前水平。结论:Nabota<®</sup>(Daewoong Co. Ltd)肉毒杆菌毒素注射后,角膜垂直轴屈光度变平,角膜斜度明显降低。注射毒素3个月后,角膜地形图改变为注射毒素前。
{"title":"Corneal Topographic Changes after Botulinum Toxin-A Injection in Patients with Essential Blepharospasm","authors":"Sangyoon Kim, Jung Hyo Ahn","doi":"10.3341/jkos.2023.64.9.845","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.9.845","url":null,"abstract":"Purpose: To compare the corneal topographic change before and after botulinum toxin A injection in patients with essential blepharospasm.Methods: From September 2015 to December 2020, we enrolled total 20 patients, 40 eyes diagnosed with essential blepharospasm. We estimated the corneal refractive power and astigmatism before and after Nabota<sup>®</sup> (Daewoong Co. Ltd, Seoul, Korea) botulinum toxin injection at 1 and 3 months using iTrace<sup>®</sup> Topography (Software version 4.2.1., Tracey technology Inc., Houston, TX, USA). Corneal refractive power was analyzed in superior, inferior, nasal and temporal location at 1 mm, 3 mm zone. Also, steep and flat keratometry, astigmatism was measured by topography.Results: Corneal refractive power showed significant difference in superior and inferior location of 1 mm zone at 1 month after botulinum toxin injection (<i>p</i> = 0.038, <i>p</i> = 0.042). There was no significant difference in all four locations of 3 mm zone. At 1 month after toxin injection, steep keratometry was only significant reduced (<i>p</i> = 0.046) and with-the-rule astigmatism was shifted to against-the-rule astigmatism. At 3 months after toxin injection, keratometry and astigmatism was resolved to before toxin injection.Conclusions: At 1 month after Nabota<sup>®</sup> (Daewoong Co. Ltd) botulinum toxin injection, corneal refractive power at vertical axis was flattened and steep keratometry was significantly reduced. At 3 months after toxin injection, corneal topographic change was changed to before toxin injection.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135355092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in Angle of Exodeviation According to Distance after Monocular Occlusion in Intermittent Exotropia 间歇性外斜视单眼闭塞后随距离的外斜角变化
Q4 OPHTHALMOLOGY Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.832
Moon Young Park, Hyun Jin Shin
Purpose: This study investigated changes in the angle of exodeviation at different distances and the characteristics of a group that showed an increased angle following monocular occlusion in intermittent exotropia.Methods: In all, 102 patients diagnosed with basic intermittent exotropia were enrolled. The deviation angle was measured using a mirror at 33 cm, 3 m, 6 m, 12 m, and 6 m. Moreover, the deviation was measured at 33 cm and 3 m after patching the non-dominant eye for 1 hour. Patients with a higher deviation angle at 33 cm after occlusion were categorized as the ‘increased group’, whereas those with lower deviation angles were classified as the ‘stationary group’.Results: There was a male-to-female ratio of 46:56 and an average age at surgery of 9.23 years. No significant differences were observed in deviation measurements taken at 3, 6, 12, and 6 m using a mirror. However, after occlusion, there was a significant increase in deviation at 33 cm (p < 0.01). The average log value of near stereoacuity was 1.96 ± 0.35 in the increased group and 2.16 ± 0.41 in the stationary group. The group with an increased near deviation after occlusion demonstrated a significantly improved near stereoacuity (p = 0.01) and an increased proportion of good results in the near Worth 4 dot test (p = 0.03).Conclusions: Preoperative measurement of maximum deviation after 1 hour of monocular occlusion can help reduce recurrence and insufficient correction, particularly in patients with good fusional ability.
目的:本研究探讨了间歇性外斜视单眼闭塞后不同距离外斜视角度的变化及一组外斜视角度增加的特征。方法:共纳入102例诊断为原发性间歇性外斜视的患者。在33 cm, 3 m, 6 m, 12 m和6 m处使用镜面测量偏差角。此外,在非优势眼补片1小时后,在33 cm和3 m处测量偏差。咬合后33 cm偏角较高的患者被归类为“增加组”,而偏角较低的患者被归类为“平稳组”。结果:男女比例为46:56,平均手术年龄为9.23岁。在3、6、12和6 m处使用镜面进行偏差测量时,没有观察到显著差异。然而,闭塞后,偏差明显增加到33 cm (<i>p</i>& lt;0.01)。升高组近立体视敏平均对数为1.96±0.35,静止组平均对数为2.16±0.41。咬合后近偏度增加组近立体视力明显改善(<i>p</i>= 0.01),近Worth 4点测试中良好结果的比例增加(<i>p</i>= 0.03)。结论:术前测量单眼闭塞1小时后的最大偏差有助于减少复发和矫正不足,特别是对融合能力良好的患者。
{"title":"Changes in Angle of Exodeviation According to Distance after Monocular Occlusion in Intermittent Exotropia","authors":"Moon Young Park, Hyun Jin Shin","doi":"10.3341/jkos.2023.64.9.832","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.9.832","url":null,"abstract":"Purpose: This study investigated changes in the angle of exodeviation at different distances and the characteristics of a group that showed an increased angle following monocular occlusion in intermittent exotropia.Methods: In all, 102 patients diagnosed with basic intermittent exotropia were enrolled. The deviation angle was measured using a mirror at 33 cm, 3 m, 6 m, 12 m, and 6 m. Moreover, the deviation was measured at 33 cm and 3 m after patching the non-dominant eye for 1 hour. Patients with a higher deviation angle at 33 cm after occlusion were categorized as the ‘increased group’, whereas those with lower deviation angles were classified as the ‘stationary group’.Results: There was a male-to-female ratio of 46:56 and an average age at surgery of 9.23 years. No significant differences were observed in deviation measurements taken at 3, 6, 12, and 6 m using a mirror. However, after occlusion, there was a significant increase in deviation at 33 cm (<i>p</i> < 0.01). The average log value of near stereoacuity was 1.96 ± 0.35 in the increased group and 2.16 ± 0.41 in the stationary group. The group with an increased near deviation after occlusion demonstrated a significantly improved near stereoacuity (<i>p</i> = 0.01) and an increased proportion of good results in the near Worth 4 dot test (<i>p</i> = 0.03).Conclusions: Preoperative measurement of maximum deviation after 1 hour of monocular occlusion can help reduce recurrence and insufficient correction, particularly in patients with good fusional ability.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135353895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between Thyrotropin Binding Inhibitory Immunoglobulin and Strabismus-associated Thyroid Eye Disease Stability 促甲状腺激素结合抑制免疫球蛋白与斜视相关性甲状腺眼病稳定性的关系
Q4 OPHTHALMOLOGY Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.825
Jae Yul Hwang, Jae Yun Sung, Min Su Kim, Yeon-Hee Lee
Purpose: To investigate the relationship between thyrotropin binding inhibitory immunoglobulin (TBII) and deviation angle stability in strabismus-associated thyroid eye disease.Methods: A total of 25 strabismus-associated thyroid eye disease patients who were followed up for > 6 months without surgery were enrolled. To investigate the correlation between TBII levels and changes in the deviation angle, a test period of 6 months from the date of TBII measurement was established and 55 test units of the corresponding TBII levels were obtained.Results: The deviation angle had a positive correlation with the TBII levels (r = 0.473, p < 0.001), but did not correlate with sex, age, and thyroid hormone levels. Changes in the horizontal, vertical, and total deviation angles were significantly greater in the high-TBII test units compared to the normal-TBII test units (p= 0.029, = 0.032, and = 0.009, respectively).Conclusions: TBII levels were related to deviation angle stability in strabismus-associated thyroid eye disease. TBII may be a useful indicator for deviation angle stability in these patients over a period of 6 months.
目的:探讨促甲状腺素结合抑制性免疫球蛋白(TBII)与斜视相关性甲状腺眼病偏角稳定性的关系。方法:对25例斜视相关甲状腺眼病患者进行随访。6个月未手术。为了研究TBII水平与偏差角变化的相关性,建立了自TBII测量之日起6个月的测试周期,获得了相应TBII水平的55个测试单元。结果:偏离角度与TBII水平呈正相关(r = 0.473, <i>p</i>& lt;0.001),但与性别、年龄和甲状腺激素水平无关。与正常tbii测试单元相比,高tbii测试单元的水平、垂直和总偏差角的变化明显更大(<i>p</i>分别= 0.029、= 0.032和= 0.009)。结论:TBII水平与斜视相关性甲状腺眼病的偏角稳定性有关。TBII可能是这些患者在6个月内的偏离角稳定性的有用指标。
{"title":"Relationship between Thyrotropin Binding Inhibitory Immunoglobulin and Strabismus-associated Thyroid Eye Disease Stability","authors":"Jae Yul Hwang, Jae Yun Sung, Min Su Kim, Yeon-Hee Lee","doi":"10.3341/jkos.2023.64.9.825","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.9.825","url":null,"abstract":"Purpose: To investigate the relationship between thyrotropin binding inhibitory immunoglobulin (TBII) and deviation angle stability in strabismus-associated thyroid eye disease.Methods: A total of 25 strabismus-associated thyroid eye disease patients who were followed up for > 6 months without surgery were enrolled. To investigate the correlation between TBII levels and changes in the deviation angle, a test period of 6 months from the date of TBII measurement was established and 55 test units of the corresponding TBII levels were obtained.Results: The deviation angle had a positive correlation with the TBII levels (r = 0.473, <i>p</i> < 0.001), but did not correlate with sex, age, and thyroid hormone levels. Changes in the horizontal, vertical, and total deviation angles were significantly greater in the high-TBII test units compared to the normal-TBII test units (<i>p</i>= 0.029, = 0.032, and = 0.009, respectively).Conclusions: TBII levels were related to deviation angle stability in strabismus-associated thyroid eye disease. TBII may be a useful indicator for deviation angle stability in these patients over a period of 6 months.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":"230 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135355087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implications of Central Corneal Thickness-corrected Intraocular Pressure in Normal-tension Glaucoma with Reduced Central Corneal Thickness 正常眼压型青光眼伴角膜中央厚度降低的角膜中央厚度校正眼压的意义
Q4 OPHTHALMOLOGY Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.811
Sang Muk Lee, Sung Uk Baek
Purpose: Reduced central corneal thickness (CCT) is a risk factor for glaucoma progression and can impact intraocular pressure (IOP) measurement. Therefore, we investigated the glaucoma progression pattern and associated risk factors among individuals with normal-tension glaucoma (NTG) and reduced CCT.Methods: This retrospective study enrolled 187 eyes of 187 NTG patients with an open angle and a baseline IOP < 20 mmHg, adjusted for CCT. Reduced CCT was defined as < 500 µm thickness in both eyes. Patients with a history of corneal disease or surgery affecting CCT were excluded. We used Goldmann tonometry to measure baseline and CCT-corrected IOP (ccIOP; [IOP - [CCT - 545]/50 × 2.5]). The participants were divided into progressing and stable subgroups.Results: The mean CCT was 481.2 ± 17.5 µm and the mean follow-up period was 6.3 ± 2.5 years. The baseline IOP and ccIOP were 13.7 ± 2.4 and 16.6 ± 2.5 mmHg, respectively. The average visual field progression rate was -0.79 ± 1.26 dB/yr. Of the participants, 47 (26.6%) and 140 (73.4%) were in the progressing and stable group, respectively. Participants in the progressing group were older, had a higher baseline ccIOP, and had a higher proportion of pseudophakia than those in the stable group. Multivariate analysis showed that baseline ccIOP was a significant risk factor.Conclusions: Individuals presenting with NTG and reduced CCT had a relatively stable glaucoma progression rate. However, glaucoma progression was associated with old age, pseudophakia, and high baseline IOP in individuals with reduced CCT. In particular, the only significant factor associated with glaucoma progression was ccIOP. Therefore, ccIOP is a clinically significant factor in individuals with NTG and reduced CCT.
目的:角膜中央厚度(CCT)降低是青光眼进展的危险因素,并可影响眼内压(IOP)测量。因此,我们研究了正常眼压型青光眼(NTG)和CCT降低患者青光眼的进展模式和相关危险因素。方法:本回顾性研究纳入187例NTG患者的187只眼,均为开角和基线IOP <20mmhg,根据CCT调整。减少的CCT定义为<双眼厚度500µm。有角膜疾病史或手术影响CCT的患者被排除在外。我们使用Goldmann眼压计测量基线和cct校正眼压(ccIOP;[iop - [cct - 545]/50 × 2.5])。参与者被分为进展组和稳定组。结果:CCT平均值为481.2±17.5µm,平均随访时间为6.3±2.5年。基线IOP和ccIOP分别为13.7±2.4和16.6±2.5 mmHg。平均视野进展率为-0.79±1.26 dB/yr。在参与者中,进展组和稳定组分别有47人(26.6%)和140人(73.4%)。进展组的参与者年龄较大,基线ccIOP较高,假性晶状体比例高于稳定组。多因素分析显示,基线ccIOP是显著的危险因素。结论:出现NTG和减少CCT的个体青光眼的进展率相对稳定。然而,在CCT减少的个体中,青光眼的进展与老年、假性晶状体和高基线IOP有关。特别是,唯一与青光眼进展相关的重要因素是ccIOP。因此,ccIOP是NTG和CCT减少患者的临床重要因素。
{"title":"Implications of Central Corneal Thickness-corrected Intraocular Pressure in Normal-tension Glaucoma with Reduced Central Corneal Thickness","authors":"Sang Muk Lee, Sung Uk Baek","doi":"10.3341/jkos.2023.64.9.811","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.9.811","url":null,"abstract":"Purpose: Reduced central corneal thickness (CCT) is a risk factor for glaucoma progression and can impact intraocular pressure (IOP) measurement. Therefore, we investigated the glaucoma progression pattern and associated risk factors among individuals with normal-tension glaucoma (NTG) and reduced CCT.Methods: This retrospective study enrolled 187 eyes of 187 NTG patients with an open angle and a baseline IOP < 20 mmHg, adjusted for CCT. Reduced CCT was defined as < 500 µm thickness in both eyes. Patients with a history of corneal disease or surgery affecting CCT were excluded. We used Goldmann tonometry to measure baseline and CCT-corrected IOP (ccIOP; [IOP - [CCT - 545]/50 × 2.5]). The participants were divided into progressing and stable subgroups.Results: The mean CCT was 481.2 ± 17.5 µm and the mean follow-up period was 6.3 ± 2.5 years. The baseline IOP and ccIOP were 13.7 ± 2.4 and 16.6 ± 2.5 mmHg, respectively. The average visual field progression rate was -0.79 ± 1.26 dB/yr. Of the participants, 47 (26.6%) and 140 (73.4%) were in the progressing and stable group, respectively. Participants in the progressing group were older, had a higher baseline ccIOP, and had a higher proportion of pseudophakia than those in the stable group. Multivariate analysis showed that baseline ccIOP was a significant risk factor.Conclusions: Individuals presenting with NTG and reduced CCT had a relatively stable glaucoma progression rate. However, glaucoma progression was associated with old age, pseudophakia, and high baseline IOP in individuals with reduced CCT. In particular, the only significant factor associated with glaucoma progression was ccIOP. Therefore, ccIOP is a clinically significant factor in individuals with NTG and reduced CCT.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135355089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Four-flanged Technique for Scleral Fixation of a Dislocated Four-eyelet Intraocular Lens 四法兰技术治疗脱位四眼人工晶状体巩膜固定
Q4 OPHTHALMOLOGY Pub Date : 2023-09-15 DOI: 10.3341/jkos.2023.64.9.803
Byung Su Lim, Jun Su Kwon, Jae Yon Won
Purpose: To define and evaluate the short-term clinical outcomes of the four-flanged technique for scleral fixation of a dislocated four-eyelet intraocular lens (IOL).Methods: Eleven eyes of 11 patients who underwent scleral fixation of dislocated four-eyelet intraocular lenses using a four-flanged technique were studied retrospectively. We measured the best-corrected visual acuity (BCVA), corneal endothelial cell density, intraocular pressure (IOP), spherical equivalent, astigmatism, IOL tilt and decentration, and postoperative complications.Results: The BCVA was 0.25 ± 0.11 logarithm of the minimal angle of resolution (logMAR) before surgery and 0.14 ± 0.12 logMAR 6 months later (p < 0.001). The corneal endothelial cell count was 2,427 ± 384 and 2,367 ± 298/mm2 before and after surgery, respectively (p = 0.285). The spherical equivalent was 6.02 ± 4.90 and 0.11 ± 0.36 before and after surgery, respectively. There was no significant difference in astigmatism before and after surgery. The mean IOL tilt and decentration were 2.44 ± 1.68° and 0.23 ± 0.09 mm, respectively. The refractive difference was 0.11 ± 0.24 diopters (D). Postoperative complications occurred in one eye; one flange lay outside the scleral tunnel, triggering hyperemia and conjunctival inflammation.Conclusions: The four-flanged scleral fixation technique for a dislocated four-eyelet IOL improved the BCVA but did not significantly affect corneal endothelial cell loss. The procedure significantly reduced postoperative IOL tilt, decentration, and astigmatism, and may be a useful alternative to scleral fixation of a dislocated four-eyelet IOL.
目的:探讨四翼缘巩膜固定脱位四眼人工晶状体的近期临床效果。方法:对11例采用四翼缘巩膜固定脱位四孔人工晶状体患者11只眼进行回顾性研究。我们测量了最佳矫正视力(BCVA)、角膜内皮细胞密度、眼内压(IOP)、球体当量、散光、IOL倾斜和脱位以及术后并发症。结果:BCVA术前为最小分辨角(logMAR)的0.25±0.11对数,6个月后为0.14±0.12对数(<i>p</i>& lt;0.001)。角膜内皮细胞计数分别为2,427±384个和2,367±298个/mm;术前、术后分别(<i>p</i>= 0.285)。术前和术后的球等效度分别为6.02±4.90和0.11±0.36。手术前后散光无明显差异。人工晶状体平均倾斜2.44±1.68°,离体0.23±0.09 mm。屈光差为0.11±0.24屈光度(D)。术后1眼出现并发症;一个法兰位于巩膜隧道外,引起充血和结膜炎症。结论:四翼巩膜固定技术用于脱位的四眼人工晶状体可改善BCVA,但对角膜内皮细胞损失无显著影响。该手术可显著降低术后人工晶状体倾斜、脱位和散光,可能是脱位四眼人工晶状体巩膜固定的有效替代方法。
{"title":"Four-flanged Technique for Scleral Fixation of a Dislocated Four-eyelet Intraocular Lens","authors":"Byung Su Lim, Jun Su Kwon, Jae Yon Won","doi":"10.3341/jkos.2023.64.9.803","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.9.803","url":null,"abstract":"Purpose: To define and evaluate the short-term clinical outcomes of the four-flanged technique for scleral fixation of a dislocated four-eyelet intraocular lens (IOL).Methods: Eleven eyes of 11 patients who underwent scleral fixation of dislocated four-eyelet intraocular lenses using a four-flanged technique were studied retrospectively. We measured the best-corrected visual acuity (BCVA), corneal endothelial cell density, intraocular pressure (IOP), spherical equivalent, astigmatism, IOL tilt and decentration, and postoperative complications.Results: The BCVA was 0.25 ± 0.11 logarithm of the minimal angle of resolution (logMAR) before surgery and 0.14 ± 0.12 logMAR 6 months later (<i>p</i> < 0.001). The corneal endothelial cell count was 2,427 ± 384 and 2,367 ± 298/mm<sup>2</sup> before and after surgery, respectively (<i>p</i> = 0.285). The spherical equivalent was 6.02 ± 4.90 and 0.11 ± 0.36 before and after surgery, respectively. There was no significant difference in astigmatism before and after surgery. The mean IOL tilt and decentration were 2.44 ± 1.68° and 0.23 ± 0.09 mm, respectively. The refractive difference was 0.11 ± 0.24 diopters (D). Postoperative complications occurred in one eye; one flange lay outside the scleral tunnel, triggering hyperemia and conjunctival inflammation.Conclusions: The four-flanged scleral fixation technique for a dislocated four-eyelet IOL improved the BCVA but did not significantly affect corneal endothelial cell loss. The procedure significantly reduced postoperative IOL tilt, decentration, and astigmatism, and may be a useful alternative to scleral fixation of a dislocated four-eyelet IOL.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135353898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of The Korean Ophthalmological Society
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