Pub Date : 2023-12-15DOI: 10.3341/jkos.2023.64.12.1218
Heeyong Han, B. Seol
Purpose: To investigate the effect of an epiretinal membrane (ERM) on peripapillary retinal nerve fiber layer thickness (pRNFLT), macular ganglion cell-inner plexiform layer thickness (mGCIPLT) and macular thickness (MT) in relation to glaucoma severity using swept-source optical coherence tomography (SS-OCT).Methods: In total, 105 eyes of 105 glaucoma patients with ERM were matched at a 1:1 ratio with glaucoma patients without ERM according to age, sex, cataract surgery, axial length and mean deviation based on visual field tests. The differences in pRNFLT, mGCIPLT and MT between the two groups were assessed using SS-OCT. Furthermore, the patients were divided into three glaucoma-severity groups, and the differences in pRNFLT, mGCIPLT and MT were compared between glaucoma patients with and without ERM in each group.Results: In all patients, including those with early, moderate, and advanced glaucoma, those with ERM had greater average, temporal quadrant, and 7, 8, 9, 10, and 11 o’clock pRNFLT values compared to those without ERM. Additionally, mGCIPLT and MT were thicker in glaucoma patients with ERM in all groups. The difference in pRNFLT at the 7 and 11 o’clock positions between glaucoma patients with and without ERM was significantly more pronounced in the moderate glaucoma group than in the early glaucoma group (p = 0.043 and p = 0.012, respectively).Conclusions: ERM has notable effects on the pRNFLT, mGCIPLT and MT. Furthermore, the magnitude of its effect on pRNFLT varies with glaucoma severity.
{"title":"Effect of ERM on RNFL, GCIPL and Macular Thickness According to the Severity of Glaucoma","authors":"Heeyong Han, B. Seol","doi":"10.3341/jkos.2023.64.12.1218","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.12.1218","url":null,"abstract":"Purpose: To investigate the effect of an epiretinal membrane (ERM) on peripapillary retinal nerve fiber layer thickness (pRNFLT), macular ganglion cell-inner plexiform layer thickness (mGCIPLT) and macular thickness (MT) in relation to glaucoma severity using swept-source optical coherence tomography (SS-OCT).Methods: In total, 105 eyes of 105 glaucoma patients with ERM were matched at a 1:1 ratio with glaucoma patients without ERM according to age, sex, cataract surgery, axial length and mean deviation based on visual field tests. The differences in pRNFLT, mGCIPLT and MT between the two groups were assessed using SS-OCT. Furthermore, the patients were divided into three glaucoma-severity groups, and the differences in pRNFLT, mGCIPLT and MT were compared between glaucoma patients with and without ERM in each group.Results: In all patients, including those with early, moderate, and advanced glaucoma, those with ERM had greater average, temporal quadrant, and 7, 8, 9, 10, and 11 o’clock pRNFLT values compared to those without ERM. Additionally, mGCIPLT and MT were thicker in glaucoma patients with ERM in all groups. The difference in pRNFLT at the 7 and 11 o’clock positions between glaucoma patients with and without ERM was significantly more pronounced in the moderate glaucoma group than in the early glaucoma group (p = 0.043 and p = 0.012, respectively).Conclusions: ERM has notable effects on the pRNFLT, mGCIPLT and MT. Furthermore, the magnitude of its effect on pRNFLT varies with glaucoma severity.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.3341/jkos.2023.64.12.1198
Ui Hwan Kim, Tae-Hoon Choi
Purpose: We compared the clinical outcomes of patients who received AcrySof IQ Panoptix TFNT00 (Alcon, Fort Worth, TX, USA), a diffractive trifocal intraocular lens (IOL), or TECNIS Synergy ZFR00V (Johnson & Johnson Vision, Santa Ana, CA, USA), a hybrid multifocal-extended depth of focus (EDOF) IOL.Methods: In total, 26 eyes of 13 patients who underwent bilateral implantation of the diffractive trifocal IOL (group A) and 24 eyes of 12 patients who underwent bilateral implantation of the hybrid multifocal-EDOF IOL (group B) were included. We assessed visual acuity using the logarithm of the minimal angle of resolution (logMAR) scale and evaluated the visual performance of both groups, including uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA) and the defocus curve at 1 month postoperatively. In addition, we measured contrast sensitivity and administered a satisfaction questionnaire at 3 months postoperatively.Results: At 1 month postoperatively, group B demonstrated significantly better monocular UDVA, UNVA and binocular UNVA compared to group A (0.07 ± 0.07, 0.24 ± 0.16, and 0.18 ± 0.15 vs. 0.13 ± 0.09, 0.33 ± 0.14, and 0.29 ± 0.11; p < 0.05). In addition, group B exhibited higher visual acuities in the monocular and binocular defocus curves at +1.00 diopters (D), -3.00 D, -3.50 D, and +1.00 D (p < 0.05). Notably, the binocular defocus curves of both groups demonstrated excellent logMAR visual acuities (better than 0.2) in the range of 0.00 to -3.00 D. However, no significant differences were observed between the groups in contrast sensitivity or satisfaction questionnaire responses for visual acuity at 3 months postoperatively (p > 0.05).Conclusions: The hybrid multifocal-EDOF IOL demonstrates superior near visual acuity compared to the diffractive trifocal IOL. However, both IOLs exhibit excellent visual acuity at distant, intermediate, and near distances.
{"title":"Visual and Refractive Outcomes of Diffractive Trifocal Versus Hybrid Multifocal-extended Depth of Focus Intraocular Lenses","authors":"Ui Hwan Kim, Tae-Hoon Choi","doi":"10.3341/jkos.2023.64.12.1198","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.12.1198","url":null,"abstract":"Purpose: We compared the clinical outcomes of patients who received AcrySof IQ Panoptix TFNT00 (Alcon, Fort Worth, TX, USA), a diffractive trifocal intraocular lens (IOL), or TECNIS Synergy ZFR00V (Johnson & Johnson Vision, Santa Ana, CA, USA), a hybrid multifocal-extended depth of focus (EDOF) IOL.Methods: In total, 26 eyes of 13 patients who underwent bilateral implantation of the diffractive trifocal IOL (group A) and 24 eyes of 12 patients who underwent bilateral implantation of the hybrid multifocal-EDOF IOL (group B) were included. We assessed visual acuity using the logarithm of the minimal angle of resolution (logMAR) scale and evaluated the visual performance of both groups, including uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA) and the defocus curve at 1 month postoperatively. In addition, we measured contrast sensitivity and administered a satisfaction questionnaire at 3 months postoperatively.Results: At 1 month postoperatively, group B demonstrated significantly better monocular UDVA, UNVA and binocular UNVA compared to group A (0.07 ± 0.07, 0.24 ± 0.16, and 0.18 ± 0.15 vs. 0.13 ± 0.09, 0.33 ± 0.14, and 0.29 ± 0.11; p < 0.05). In addition, group B exhibited higher visual acuities in the monocular and binocular defocus curves at +1.00 diopters (D), -3.00 D, -3.50 D, and +1.00 D (p < 0.05). Notably, the binocular defocus curves of both groups demonstrated excellent logMAR visual acuities (better than 0.2) in the range of 0.00 to -3.00 D. However, no significant differences were observed between the groups in contrast sensitivity or satisfaction questionnaire responses for visual acuity at 3 months postoperatively (p > 0.05).Conclusions: The hybrid multifocal-EDOF IOL demonstrates superior near visual acuity compared to the diffractive trifocal IOL. However, both IOLs exhibit excellent visual acuity at distant, intermediate, and near distances.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.3341/jkos.2023.64.12.1232
Hyuna Kim, Ungsoo Samuel Kim
Purpose: To investigate the status of low-vision care in Korea and the needs of ophthalmologists, and to define future directions for the diagnosis and treatment of low-vision patients.Methods: Twenty survey questions exploring low-vision knowledge were emailed to members of the Korean Ophthalmological Society, and the responses were analyzed.Results: In total, 158 responses were collected from ophthalmologists working in different institutions, including 62 (45.6%) at university hospitals. Many respondents (91, 57.6%) reported knowing the criteria for low vision, but approximately half (74, 46.9%) reported that they had little or no knowledge of low vision in general. More than half of the respondents (87, 55.1%) had never written a prescription for a visual aid, and only 32 (20.2%) were able to prescribe such aids. The principal reasons for hesitation in the treatment of low-vision patients were lack of knowledge (117, 74.5%) and poor medical reimbursement (41, 26.1%). Many respondents (152, 96.2%) wanted to learn more about low vision, and approximately half (71, 45.5%; 74, 47.4%) felt that the current low-vision care environment in Korea requires improvement.Conclusions: Despite the increasing need for low-vision care in South Korea, the number of ophthalmologists who can provide such care (including prescriptions for visual aids) is insufficient. Lack of education and poor medical reimbursement are important problems. Low-vision clinics must promote outreach activities, and institutions should develop programs to educate ophthalmologists.
{"title":"Current Status of Korean Low-vision Care According to a Survey of Korean Ophthalmological Society Members","authors":"Hyuna Kim, Ungsoo Samuel Kim","doi":"10.3341/jkos.2023.64.12.1232","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.12.1232","url":null,"abstract":"Purpose: To investigate the status of low-vision care in Korea and the needs of ophthalmologists, and to define future directions for the diagnosis and treatment of low-vision patients.Methods: Twenty survey questions exploring low-vision knowledge were emailed to members of the Korean Ophthalmological Society, and the responses were analyzed.Results: In total, 158 responses were collected from ophthalmologists working in different institutions, including 62 (45.6%) at university hospitals. Many respondents (91, 57.6%) reported knowing the criteria for low vision, but approximately half (74, 46.9%) reported that they had little or no knowledge of low vision in general. More than half of the respondents (87, 55.1%) had never written a prescription for a visual aid, and only 32 (20.2%) were able to prescribe such aids. The principal reasons for hesitation in the treatment of low-vision patients were lack of knowledge (117, 74.5%) and poor medical reimbursement (41, 26.1%). Many respondents (152, 96.2%) wanted to learn more about low vision, and approximately half (71, 45.5%; 74, 47.4%) felt that the current low-vision care environment in Korea requires improvement.Conclusions: Despite the increasing need for low-vision care in South Korea, the number of ophthalmologists who can provide such care (including prescriptions for visual aids) is insufficient. Lack of education and poor medical reimbursement are important problems. Low-vision clinics must promote outreach activities, and institutions should develop programs to educate ophthalmologists.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.3341/jkos.2023.64.12.1238
Kyeong Joo Lee, H. Sun, K. Choi, S. J. Lee, Hyuna Kim
Purpose: Binocular diplopia is a primary complication that may arise after scleral buckling surgery in patients with rhegmatogenous retinal detachment. This study examined the incidence of and risk factors for binocular diplopia after scleral buckling surgery; it also evaluated the rate of strabismus surgery success in patients with diplopia.Methods: Medical records of 417 patients who underwent scleral buckling surgery for rhegmatogenous retinal detachment at a single institution from January 2017 to June 2022 were retrospectively reviewed. Patients who experienced binocular diplopia for > 6 months were included in the diplopia group.Results: After surgery, 22 patients (5.3%) developed binocular diplopia. There were no significant correlations of diplopia onset with buckle position (i.e., the affected muscle), cryophotocoagulation, subretinal fluid drainage, and the use of gas or oil injections. Prism therapy restored binocular single vision in three patients. Ten patients chose to undergo strabismus surgery, and one patient underwent encircling band removal. All strabismus surgery patients displayed adhesion between the buckle and extraocular muscle. After surgery, 60% of these patients regained binocular single vision.Conclusions: Clear risk factors leading to ocular movement disorders and diplopia after scleral buckling remain undefined. If diplopia persists despite prism-based conservative treatment, strabismus surgery may offer relief.
{"title":"Ocular Movement Disorder after Scleral Buckling Surgery in Patients with Retinal Detachment","authors":"Kyeong Joo Lee, H. Sun, K. Choi, S. J. Lee, Hyuna Kim","doi":"10.3341/jkos.2023.64.12.1238","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.12.1238","url":null,"abstract":"Purpose: Binocular diplopia is a primary complication that may arise after scleral buckling surgery in patients with rhegmatogenous retinal detachment. This study examined the incidence of and risk factors for binocular diplopia after scleral buckling surgery; it also evaluated the rate of strabismus surgery success in patients with diplopia.Methods: Medical records of 417 patients who underwent scleral buckling surgery for rhegmatogenous retinal detachment at a single institution from January 2017 to June 2022 were retrospectively reviewed. Patients who experienced binocular diplopia for > 6 months were included in the diplopia group.Results: After surgery, 22 patients (5.3%) developed binocular diplopia. There were no significant correlations of diplopia onset with buckle position (i.e., the affected muscle), cryophotocoagulation, subretinal fluid drainage, and the use of gas or oil injections. Prism therapy restored binocular single vision in three patients. Ten patients chose to undergo strabismus surgery, and one patient underwent encircling band removal. All strabismus surgery patients displayed adhesion between the buckle and extraocular muscle. After surgery, 60% of these patients regained binocular single vision.Conclusions: Clear risk factors leading to ocular movement disorders and diplopia after scleral buckling remain undefined. If diplopia persists despite prism-based conservative treatment, strabismus surgery may offer relief.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.3341/jkos.2023.64.12.1259
Sejun Park, Jong Beom Park, Kiyoung Kim
Purpose: To report a case of Vogt-Koyanagi-Harada-like syndrome that occurred during immunotherapy (pembrolizumab) in a patient with non-small-cell lung cancer (NSCLC).Case summary: A 64-year-old female visited our clinic complaining of decreased visual acuity in both eyes. The patient had NSCLC and had been prescribed immunotherapy (pembrolizumab) by the Department of Pulmonology. Fundus examination and optical coherence tomography revealed multiple intraretinal cysts and subretinal fluid in both eyes. After evaluation using fluorescein and indocyanine green angiography, Vogt-Koyanagi-Harada (VKH) disease was diagnosed in both eyes and oral prednisolone 40 mg/day was prescribed for 2 weeks. At an outpatient visit at that time, the symptoms had improved, and fundus examination and optical coherence tomography revealed decreases in the number of intraretinal cysts and the subretinal fluid level. Oral prednisolone was reduced to 20 mg/day for 2 weeks. At an outpatient visit at that time, the symptoms had further improved; no cysts or subretinal fluid were apparent on fundus examination or optical coherence tomography, and only a small amount of subretinal fluid was present near the macula of the right eye.Conclusions: VKH disease may develop during immunotherapy (pembrolizumab) but can be rapidly diagnosed and treated with oral steroids.
{"title":"A Case of Vogt-Koyanagi-Harada-like Syndrome Associated with Immunotherapy (Pembrolizumab)","authors":"Sejun Park, Jong Beom Park, Kiyoung Kim","doi":"10.3341/jkos.2023.64.12.1259","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.12.1259","url":null,"abstract":"Purpose: To report a case of Vogt-Koyanagi-Harada-like syndrome that occurred during immunotherapy (pembrolizumab) in a patient with non-small-cell lung cancer (NSCLC).Case summary: A 64-year-old female visited our clinic complaining of decreased visual acuity in both eyes. The patient had NSCLC and had been prescribed immunotherapy (pembrolizumab) by the Department of Pulmonology. Fundus examination and optical coherence tomography revealed multiple intraretinal cysts and subretinal fluid in both eyes. After evaluation using fluorescein and indocyanine green angiography, Vogt-Koyanagi-Harada (VKH) disease was diagnosed in both eyes and oral prednisolone 40 mg/day was prescribed for 2 weeks. At an outpatient visit at that time, the symptoms had improved, and fundus examination and optical coherence tomography revealed decreases in the number of intraretinal cysts and the subretinal fluid level. Oral prednisolone was reduced to 20 mg/day for 2 weeks. At an outpatient visit at that time, the symptoms had further improved; no cysts or subretinal fluid were apparent on fundus examination or optical coherence tomography, and only a small amount of subretinal fluid was present near the macula of the right eye.Conclusions: VKH disease may develop during immunotherapy (pembrolizumab) but can be rapidly diagnosed and treated with oral steroids.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.3341/jkos.2023.64.12.1263
Se Ik Park, Shin Hyeong Park, Bum Jun Kim, Woohyuk Lee, Yong Seop Han
Purpose: Despite the relatively low incidence of sympathetic ophthalmia, prompt diagnosis is essential to prevent visual impairment in both eyes. Here, we present a case of sympathetic ophthalmia, emphasizing distinctive imaging findings.Case summary: A 64-year-old male patient presented with complaints of right ocular pain and visual disturbances occurring 3 weeks after blunt trauma. The patient had a history of ophthalmologic surgeries, including cataract surgery in both eyes and intraocular lens trans-scleral fixation in the right eye. A primary suture was performed in the right eye due to iris prolapse through the scleral incision site and anterior chamber hemorrhage. At 1 week post-surgery, the patient reported diminished visual acuity in the left eye. Further assessment using wide-field fundus photography, optical coherence tomography, and fluorescein angiography revealed multiple focal hyperfluorescence leakage and serous retinal detachment. Consequently, sympathetic ophthalmia was diagnosed. Intravenous administration of high-dose steroids led to significant symptom improvement.Conclusions: We present a patient with a history of multiple ophthalmic surgeries and contralateral eye trauma indicative of sympathetic ophthalmia. Imaging modalities revealed typical findings for this condition. This case report emphasizes the importance of early diagnosis and treatment of sympathetic ophthalmia.
{"title":"Multimodal Imaging Assessment of Typical Sympathetic Ophthalmia: A Case Report","authors":"Se Ik Park, Shin Hyeong Park, Bum Jun Kim, Woohyuk Lee, Yong Seop Han","doi":"10.3341/jkos.2023.64.12.1263","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.12.1263","url":null,"abstract":"Purpose: Despite the relatively low incidence of sympathetic ophthalmia, prompt diagnosis is essential to prevent visual impairment in both eyes. Here, we present a case of sympathetic ophthalmia, emphasizing distinctive imaging findings.Case summary: A 64-year-old male patient presented with complaints of right ocular pain and visual disturbances occurring 3 weeks after blunt trauma. The patient had a history of ophthalmologic surgeries, including cataract surgery in both eyes and intraocular lens trans-scleral fixation in the right eye. A primary suture was performed in the right eye due to iris prolapse through the scleral incision site and anterior chamber hemorrhage. At 1 week post-surgery, the patient reported diminished visual acuity in the left eye. Further assessment using wide-field fundus photography, optical coherence tomography, and fluorescein angiography revealed multiple focal hyperfluorescence leakage and serous retinal detachment. Consequently, sympathetic ophthalmia was diagnosed. Intravenous administration of high-dose steroids led to significant symptom improvement.Conclusions: We present a patient with a history of multiple ophthalmic surgeries and contralateral eye trauma indicative of sympathetic ophthalmia. Imaging modalities revealed typical findings for this condition. This case report emphasizes the importance of early diagnosis and treatment of sympathetic ophthalmia.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.3341/jkos.2023.64.12.1141
Yeon Ju Lim, Do Hee Jung, K. Pak, Chan-Ho Cho
Purpose: We compared corneal higher-order aberration (HOA) measurements between the Pentacam® HR (PC), which uses the Scheimpflug principle, and the iTraceTM aberrometer (IT), which evaluates Placido disc topography.Methods: We retrospectively analyzed 109 eyes of 87 patients without a history of ocular surface disease during the period from January 2021 to December 2022; both devices were used on the same day. We calculated the root mean square values (μm) of corneal total HOA and of the corneal 3rd- and 4th-order HOA at a pupil diameter of 4 mm. Data were compared by Bland-Altman plots for agreement analysis and Pearson correlation coefficient for correlation analysis.Results: There was no significant difference in the total HOA (p = 0.145), coma (p = 0.309), or secondary astigmatism (p = 0.080) between the PC and IT measurements; all other HOAs significantly differed between devices (p < 0.001). In the correlation analysis, the total HOA (r = 0.605, p < 0.001) and coma (r = 0.634, p < 0.001) were moderately correlated between the two devices; the other HOAs showed low degree of correlations. In the Bland-Altman plot analysis, all HOAs showed low agreement between the two devices.Conclusions: Corneal total HOA and coma measured by the two devices were significantly correlated between the two devices, but other HOAs showed significant differences in measurement and low correlations. Therefore, corneal HOA measurements cannot be interpreted interchangeably between the two devices.
{"title":"Comparison of Corneal Higher-order Aberrations Measured by Scheimpflug Camera and Placido Disc-based Topography in Korean Patients","authors":"Yeon Ju Lim, Do Hee Jung, K. Pak, Chan-Ho Cho","doi":"10.3341/jkos.2023.64.12.1141","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.12.1141","url":null,"abstract":"Purpose: We compared corneal higher-order aberration (HOA) measurements between the Pentacam® HR (PC), which uses the Scheimpflug principle, and the iTraceTM aberrometer (IT), which evaluates Placido disc topography.Methods: We retrospectively analyzed 109 eyes of 87 patients without a history of ocular surface disease during the period from January 2021 to December 2022; both devices were used on the same day. We calculated the root mean square values (μm) of corneal total HOA and of the corneal 3rd- and 4th-order HOA at a pupil diameter of 4 mm. Data were compared by Bland-Altman plots for agreement analysis and Pearson correlation coefficient for correlation analysis.Results: There was no significant difference in the total HOA (p = 0.145), coma (p = 0.309), or secondary astigmatism (p = 0.080) between the PC and IT measurements; all other HOAs significantly differed between devices (p < 0.001). In the correlation analysis, the total HOA (r = 0.605, p < 0.001) and coma (r = 0.634, p < 0.001) were moderately correlated between the two devices; the other HOAs showed low degree of correlations. In the Bland-Altman plot analysis, all HOAs showed low agreement between the two devices.Conclusions: Corneal total HOA and coma measured by the two devices were significantly correlated between the two devices, but other HOAs showed significant differences in measurement and low correlations. Therefore, corneal HOA measurements cannot be interpreted interchangeably between the two devices.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138997910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-15DOI: 10.3341/jkos.2023.64.10.951
Ha Eun Sim, Su Jeong You, Jin Choi
Purpose: We investigated disparities in retinal nerve fiber layer (RNFL) thickness surrounding the optic disc among pediatric migraine patients based on the presence of a concomitant visual aura.Methods: We used optical coherence tomography to measure RNFL thickness around the optic disc in children with migraines and no organic diseases, along with a control group of healthy children. Differences in RNFL thickness were analyzed based on the pattern of prognostic symptoms. Additionally, we investigated the effects of migraine duration and frequency on RNFL thickness.Results: In total, 45 children with migraine and 30 healthy controls were enrolled in this study. Among the children with migraine, 15 experienced visual aura, whereas 30 did not exhibit visual aura. Visual prognostic symptoms included blurred vision, scotoma, and scintillating scotoma. Seven children presented with blurred vision and scotoma, whereas eight reported scintillating scotomas. The mean RNFL thickness around the optic disc was significantly lower in patients with blurred vision and scotomas (89.19 ± 7.99 μm) compared with the control group (98.79 ± 8.49 μm), patients without visual aura (100.55 ± 6.43 μm), and patients with scintillating scotoma (102.21 ± 10.13 μm, p < 0.05).Conclusions: RNFL thickness around the optic disc was significantly reduced in children with migraine who reported symptoms of blurred vision and scotoma.
目的:我们研究了儿童偏头痛患者视盘周围视网膜神经纤维层(RNFL)厚度的差异，这是基于伴随视觉先兆的存在。方法:我们使用光学相干断层扫描测量无器质性疾病的偏头痛儿童视盘周围RNFL厚度，并与对照组健康儿童进行比较。根据预后症状的模式分析RNFL厚度的差异。此外，我们还研究了偏头痛持续时间和频率对RNFL厚度的影响。结果:共有45名患有偏头痛的儿童和30名健康对照者参加了这项研究。在患有偏头痛的儿童中，15人有视觉先兆，30人没有。视觉预后症状包括视力模糊、暗斑和闪烁性暗斑。7名儿童表现为视力模糊和暗斑，8名报告为闪烁性暗斑。视盘周围RNFL平均厚度:视力模糊伴暗点组(89.19±7.99 μm)明显低于对照组(98.79±8.49 μm)、无视觉先兆组(100.55±6.43 μm)、闪烁性暗点组(102.21±10.13 μm)， p <0.05)。结论:报告视力模糊和暗斑症状的偏头痛患儿视盘周围RNFL厚度显著减少。
{"title":"Analysis of Retinal Nerve Fiber Layer Thickness in Pediatric Migraine Using Optical Coherence Tomography","authors":"Ha Eun Sim, Su Jeong You, Jin Choi","doi":"10.3341/jkos.2023.64.10.951","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.10.951","url":null,"abstract":"Purpose: We investigated disparities in retinal nerve fiber layer (RNFL) thickness surrounding the optic disc among pediatric migraine patients based on the presence of a concomitant visual aura.Methods: We used optical coherence tomography to measure RNFL thickness around the optic disc in children with migraines and no organic diseases, along with a control group of healthy children. Differences in RNFL thickness were analyzed based on the pattern of prognostic symptoms. Additionally, we investigated the effects of migraine duration and frequency on RNFL thickness.Results: In total, 45 children with migraine and 30 healthy controls were enrolled in this study. Among the children with migraine, 15 experienced visual aura, whereas 30 did not exhibit visual aura. Visual prognostic symptoms included blurred vision, scotoma, and scintillating scotoma. Seven children presented with blurred vision and scotoma, whereas eight reported scintillating scotomas. The mean RNFL thickness around the optic disc was significantly lower in patients with blurred vision and scotomas (89.19 ± 7.99 μm) compared with the control group (98.79 ± 8.49 μm), patients without visual aura (100.55 ± 6.43 μm), and patients with scintillating scotoma (102.21 ± 10.13 μm, p < 0.05).Conclusions: RNFL thickness around the optic disc was significantly reduced in children with migraine who reported symptoms of blurred vision and scotoma.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136184801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-15DOI: 10.3341/jkos.2023.64.10.930
Hyun Woo Kim, Chong Eun Lee, Sam Seo, Kyoo Won Lee, Chang Hoon Lee
Purpose: To study the short-term intraocular pressure (IOP)-lowering effect and optic nerve head (ONH) blood flow improvement after switching from latanoprost 0.005% w/v to latanoprostene bunod 0.024% w/v.Methods: This prospective study ran from May 2022 to December 2022 and included 40 patients with open-angle glaucoma who switched from latanoprost 0.005% w/v to latanoprostene bunod 0.024% w/v. The IOP, ONH blood flow, and conjunctival hyperemia, corneal erosion, and eyelid pigmentation status were measured 3 months after switching. We recorded all possible side effects.Results: The baseline IOP significantly dropped from 17.53 ± 6.49 to 16.00 ± 8.06 mmHg at 3 months (p = 0.032). The best-corrected visual acuity did not significantly change (0.24 ± 0.19 to 0.23 ± 0.16); neither did eyelid pigmentation (1.16 ± 0.78 to 1.16 ± 0.82) nor the corneal erosion score (0.58 ± 0.85 to 0.39 ± 0.76). Conjunctival hyperemia significantly decreased from 2.00 ± 0.69 to 1.67 ± 0.63 (p = 0.010). Neither the whole-image vessel density nor the peripapillary vessel density significantly changed. However, pruritus became significantly worse after the change (p = 0.008).Conclusions: In the short term, latanoprostene bunod 0.024% w/v lowered the IOP more effectively than did latanoprost 0.005% w/v. However, there was no significant change in ONH blood flow after the switch.
{"title":"Latanoprostene Bunod 0.024% w/v Treatment of Open-anlge Glaucoma: Short-term Effects, Safety, and Changes in Ocular Blood","authors":"Hyun Woo Kim, Chong Eun Lee, Sam Seo, Kyoo Won Lee, Chang Hoon Lee","doi":"10.3341/jkos.2023.64.10.930","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.10.930","url":null,"abstract":"Purpose: To study the short-term intraocular pressure (IOP)-lowering effect and optic nerve head (ONH) blood flow improvement after switching from latanoprost 0.005% w/v to latanoprostene bunod 0.024% w/v.Methods: This prospective study ran from May 2022 to December 2022 and included 40 patients with open-angle glaucoma who switched from latanoprost 0.005% w/v to latanoprostene bunod 0.024% w/v. The IOP, ONH blood flow, and conjunctival hyperemia, corneal erosion, and eyelid pigmentation status were measured 3 months after switching. We recorded all possible side effects.Results: The baseline IOP significantly dropped from 17.53 ± 6.49 to 16.00 ± 8.06 mmHg at 3 months (p = 0.032). The best-corrected visual acuity did not significantly change (0.24 ± 0.19 to 0.23 ± 0.16); neither did eyelid pigmentation (1.16 ± 0.78 to 1.16 ± 0.82) nor the corneal erosion score (0.58 ± 0.85 to 0.39 ± 0.76). Conjunctival hyperemia significantly decreased from 2.00 ± 0.69 to 1.67 ± 0.63 (p = 0.010). Neither the whole-image vessel density nor the peripapillary vessel density significantly changed. However, pruritus became significantly worse after the change (p = 0.008).Conclusions: In the short term, latanoprostene bunod 0.024% w/v lowered the IOP more effectively than did latanoprost 0.005% w/v. However, there was no significant change in ONH blood flow after the switch.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136185310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-15DOI: 10.3341/jkos.2023.64.10.913
Young Min Park, Kang Ju Son, Eun Jee Chung, Seo Hee Kim
Purpose: We analyzed the incidence and prevalence of neovascular age-related macular degeneration (AMD) and the treatment patterns of AMD in response to changes in health insurance policies in South Korea.Methods: We retrospectively analyzed the incidence and prevalence of neovascular AMD in patients diagnosed between 2010 and 2019. Data were extracted from the Korean National Health Insurance System database. The incidence and prevalence per 10,000 person-years and corresponding 95% confidence intervals were calculated. Furthermore, we recorded the usage of ranibizumab and aflibercept among newly diagnosed patients with neovascular AMD between 2010 and 2014.Results: In total, 90,012 patients were diagnosed with neovascular AMD between 2010 and 2019. The incidence of neovascular AMD increased with age, except for individuals aged ≥ 90 years. The prevalence of neovascular AMD increased significantly from 30.29 per 10,000 person-years in 2010 to 50.8 per 10,000 person-years in 2019. The rate of intravitreal ranibizumab injections decreased following the introduction of aflibercept in 2014. Patients who switched from ranibizumab to aflibercept exhibited a higher drug switch rate than those who switched from aflibercept to ranibizumab (28.83% vs. 8.40%). Among newly diagnosed patients, approximately 65% received treatment covered by the health insurance system. On average, six injections were administered per year between 2010 and 2019; the number of injections increased in accordance with the maximum limit supported by the government.Conclusions: The incidence and prevalence of neovascular AMD demonstrated an increasing trend. The treatment patterns are influenced by changes in government funding support policies. These findings provide valuable information for planning neovascular AMD treatment.
{"title":"Analyzing Treatment Patterns for Neovascular Age-related Macular Degeneration with Expansion of the Korean Health Insurance Policy","authors":"Young Min Park, Kang Ju Son, Eun Jee Chung, Seo Hee Kim","doi":"10.3341/jkos.2023.64.10.913","DOIUrl":"https://doi.org/10.3341/jkos.2023.64.10.913","url":null,"abstract":"Purpose: We analyzed the incidence and prevalence of neovascular age-related macular degeneration (AMD) and the treatment patterns of AMD in response to changes in health insurance policies in South Korea.Methods: We retrospectively analyzed the incidence and prevalence of neovascular AMD in patients diagnosed between 2010 and 2019. Data were extracted from the Korean National Health Insurance System database. The incidence and prevalence per 10,000 person-years and corresponding 95% confidence intervals were calculated. Furthermore, we recorded the usage of ranibizumab and aflibercept among newly diagnosed patients with neovascular AMD between 2010 and 2014.Results: In total, 90,012 patients were diagnosed with neovascular AMD between 2010 and 2019. The incidence of neovascular AMD increased with age, except for individuals aged ≥ 90 years. The prevalence of neovascular AMD increased significantly from 30.29 per 10,000 person-years in 2010 to 50.8 per 10,000 person-years in 2019. The rate of intravitreal ranibizumab injections decreased following the introduction of aflibercept in 2014. Patients who switched from ranibizumab to aflibercept exhibited a higher drug switch rate than those who switched from aflibercept to ranibizumab (28.83% vs. 8.40%). Among newly diagnosed patients, approximately 65% received treatment covered by the health insurance system. On average, six injections were administered per year between 2010 and 2019; the number of injections increased in accordance with the maximum limit supported by the government.Conclusions: The incidence and prevalence of neovascular AMD demonstrated an increasing trend. The treatment patterns are influenced by changes in government funding support policies. These findings provide valuable information for planning neovascular AMD treatment.","PeriodicalId":17341,"journal":{"name":"Journal of The Korean Ophthalmological Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136185021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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