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Racial and Ethnic Disparities in Helicopter Transport Utilization in Severely Injury Children 严重受伤儿童使用直升机运输的种族和民族差异
IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.1016/j.jnma.2024.07.049
Christian Mpody MD, PhD, MBA, Joseph D. Tobias MD, Olubukola O. Nafiu MD
<div><h3>Introduction</h3><p>In the United States, trauma is a leading cause of pediatric mortality. In severe injury, every second counts towards maximizing survival, an urgency encapsulated in the concept of the 'Golden Hour.' In this context, helicopter air ambulances is as a vital component of the emergency medical services system, reducing the time to definitive care for severely injured patients. However, persisting racial and ethnic disparities in trauma outcomes in the US raise questions about whether non-clinical factors, such as race or ethnicity, influence the deployment of life saving interventions, such as air transport for severely injured children. In this study, we evaluated whether there is a racial or ethnic disparity in the risk-adjusted use of helicopter ambulance following severe pediatric trauma. We also evaluated whether the gaps in helicopter utilization between children of different races and ethnicity have begun to narrow or widen over time.</p></div><div><h3>Methods</h3><p>We conducted a population-based, 1:1 propensity-score matched, retrospective cohort study using data from the National Trauma Data Bank (NTDB) between 2017 and 2022. Our cohort included 42,812children (15) and had and emergency department disposition to the operating room or the ICU at level I or II trauma centers. Our primary outcome was the risk-adjusted transport mode comparing racial/ethnic groups (helicopter ambulance vs. ground ambulance). We used linear risk and log-binomial regression models and summarized the results as adjusted relative risk (RRadj), absolute risk difference (RDadj) along with their 95% confidence intervals (CIs). To account for clinical characteristics that could influence the decision to use helicopter transport, the propensity score models controlled for age, sex, hospital teaching status, American College of Surgeons verification level, state designation, hospital bed size, patient's primary insurance, injury intentionality, injury mechanism, chronic complex condition, body region, injury severity score, EMS reported Glasgow coma scale, heart rate and systolic blood pressure, and a distance indicator between injury site and receiving hospital.</p></div><div><h3>Result</h3><p>Helicopter transport was associated with a lower mortality risk compared to ground transport (RRadj: 0.86, 95%CI: 0.79 to 0.93, P-value < 0.001). Despite the mortality benefits of helicopter utilization, non-Hispanic Black children were 50% relative less likely to be air transported, compared to Non-Hispanic White children (20.0% vs. 33.6%, RDadj: -20.0%, 95% CI: -22.0 to -18.0, P-value < 0.001). Similarly, Non-Hispanic Others (24.7% vs. 33.6%, RDadj: -11.0%, 95% CI: -14.0 to -8.0%, P-value < 0.001), and Hispanics (24.0% vs. 33.6%, RDadj: -11.0%, 95% CI: -13.0 to -10.0%, P-value < 0.001) were both less likely to be air transported compared to Non-Hispanic White children—Figure 1. We found no statistical evidence of narrowing of the dispar
导言在美国,创伤是导致儿科死亡的主要原因。在重伤情况下,每一秒都在为最大限度地提高存活率而努力,"黄金一小时 "的概念概括了这一紧迫性。在这种情况下,直升机空中救护是紧急医疗服务系统的重要组成部分,它缩短了重伤患者获得最终治疗的时间。然而,美国创伤治疗结果中持续存在的种族和民族差异引发了人们的疑问:种族或民族等非临床因素是否会影响救生干预措施的部署,例如对严重受伤儿童的空中转运。在这项研究中,我们评估了严重儿科创伤后直升机救护的风险调整使用是否存在种族或民族差异。我们还评估了不同种族和民族的儿童在直升机使用方面的差距是否随着时间的推移而开始缩小或扩大。方法我们利用美国国家创伤数据库(NTDB)在 2017 年至 2022 年期间的数据,开展了一项基于人口、1:1 倾向性分数匹配的回顾性队列研究。我们的队列中包括 42812 名儿童(15 岁),他们都曾在急诊科就诊,并被送往一级或二级创伤中心的手术室或重症监护室。我们的主要结果是比较种族/族裔群体(直升机救护车与地面救护车)的风险调整后转运模式。我们使用了线性风险和对数二项式回归模型,并将结果总结为调整后的相对风险 (RRadj)、绝对风险差异 (RDadj) 及其 95% 置信区间 (CI)。为了考虑可能影响使用直升机转运决定的临床特征,倾向得分模型控制了年龄、性别、医院教学状况、美国外科学院验证级别、州指定、医院床位大小、患者的主要保险、受伤意图、受伤机制、慢性复杂情况、身体部位、受伤严重程度评分、EMS 报告的格拉斯哥昏迷量表、心率和收缩压以及受伤地点与接收医院之间的距离指标。结果与地面转运相比,直升机转运的死亡率风险较低(RRadj:0.86,95%CI:0.79 至 0.93,P 值为 0.001)。尽管使用直升机可降低死亡率,但与非西班牙裔白人儿童相比,非西班牙裔黑人儿童接受空中转运的可能性相对降低了 50%(20.0% vs. 33.6%,RDadj:-20.0%,95% CI:-22.0 to -18.0,P 值为 0.001)。同样,与非西班牙裔白人儿童相比,非西班牙裔其他儿童(24.7% vs. 33.6%,RDadj:-11.0%,95% CI:-14.0 到 -8.0%,P-value < 0.001)和西班牙裔儿童(24.0% vs. 33.6%,RDadj:-11.0%,95% CI:-13.0 到 -10.0%,P-value < 0.001)被空运的可能性都更小--图 1。我们没有发现在研究期间差距缩小的统计证据(种族/族裔与年份之间交互作用的似然比检验,P 值 = 0.180)。这些差距并没有随着时间的推移而缩小,这对目前扩大直升机救护项目的有效性提出了挑战。随着儿科创伤护理的不断发展,我们有责任确保获得快速救生护理的机会不会有意或无意地受到种族和民族等非临床需求的影响。
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引用次数: 0
Addressing Disparities in Cardiovascular Disease, Cancer, COVID and HIV 消除心血管疾病、癌症、COVID 和艾滋病毒方面的差异
IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.1016/j.jnma.2024.07.010
Marie L. Borum MD, EdD, MPH, MACP, FACG, AGAF, FRCP
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引用次数: 0
Investigating the Accuracy of Obstetric-Related Educational Material Disseminated Through Social Media 调查通过社交媒体传播的产科相关教育材料的准确性
IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.1016/j.jnma.2024.07.015
Ogechukwu S. Anwaegbu BS, Smiti Gandhi BS, Gengi E. Kleto BS, Mitaire Erhieyovew BS, Deniz Isikkent MD, Rovnat Babazade MD

Introduction

In recent times, healthcare providers have leveraged Instagram to share insights into their medical specialty, providing educational content to the public in a format distinct from traditional medical norms. However, the medical domain on Instagram lacks the same level of regulation, potentially resulting in the dissemination of inaccurate information3, impacting patient experiences and health outcomes. Our study aims to evaluate the quality and accuracy of obstetric anesthesia-related content on Instagram.

Methods

A search Instagram posts for #Epidural, #EpiduralAnalgesia, #ObAnesthesiologist and #ObstetricAnesthesia was conducted. Engagement metrics were used to quantify post content reach. Medical education videos were assessed for accuracy and PEMAT-A/V to evaluate understandability and actionability.

Results

A total of 80 Instagram posts were analyzed, revealing a predominant focus on Medical Education(46%), followed by Provider Lifestyle(21%), Advertisement(16%), Research Articles(8%), Patient Experience(5%), and Medical Illustration(4%). In medical education content, 69% of posts were completely accurate, 28% were partially accurate or potentially misleading, and 3% were entirely inaccurate. When comparing video posts to picture posts: among video posts, 50% accurate information, 42% partially accurate or incomplete information, and 7% were entirely inaccurate. In contrast, picture posts demonstrated higher accuracy rates, with 81% being accurate, 19% partially accurate or potentially misleading, and none being inaccurate.

Conclusion

Our analysis illustrates diverse obstetric anesthesia-related content on Instagram. Future research should assess accuracy variations among different obstetric healthcare provider types on social media and provide strategies for healthcare providers to improve engagement, maintain accuracy, and navigate time constraints when sharing medical information.

导言近来,医疗服务提供者利用 Instagram 分享对其医疗专业的见解,以有别于传统医疗规范的形式向公众提供教育内容。然而,Instagram 上的医疗领域缺乏同等程度的监管,可能导致不准确信息的传播3 ,影响患者的体验和健康结果。我们的研究旨在评估 Instagram 上产科麻醉相关内容的质量和准确性。方法在 Instagram 上搜索 #Epidural、#EpiduralAnalgesia、#ObAnesthesiologist 和 #ObstetricAnesthesia 的帖子。参与度指标用于量化帖子内容的到达率。对医学教育视频的准确性进行了评估,并使用 PEMAT-A/V 评估了可理解性和可操作性。结果共分析了 80 篇 Instagram 帖子,结果显示,医疗教育内容占主导地位(46%),其次是医护人员生活方式(21%)、广告(16%)、研究文章(8%)、患者体验(5%)和医学插图(4%)。在医学教育内容中,69%的帖子完全准确,28%的帖子部分准确或可能存在误导,3%的帖子完全不准确。将视频帖子与图片帖子进行比较:在视频帖子中,50%的信息准确,42%的信息部分准确或不完整,7%的信息完全不准确。相比之下,图片帖子的准确率更高,81%准确,19%部分准确或有潜在误导性,无一不准确。未来的研究应评估社交媒体上不同产科医疗服务提供者类型的准确性差异,并为医疗服务提供者提供策略,以提高参与度、保持准确性并在分享医疗信息时应对时间限制。
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引用次数: 0
Segmental Analysis of Racial and Ethnic Diversity in the Pipeline to Anesthesiology Fellowship from 2012-2022 2012-2022 年麻醉学研究员培养计划中种族和民族多样性的分段分析
IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.1016/j.jnma.2024.07.016
Candice S Dyce BA, Megan Darrell B.A., Mill Etienne M.D., MPH, FAAES, FAAN

Purpose

Racial and ethnic minorities have historically experienced inequities in pain assessment and analgesia delivery, as well as worse perioperative outcomes. An equally diverse physician workforce is necessary to care for the needs of this population. Despite ACGME's interest in prioritizing expansion and support of a diverse workforce, the percentage of URiM Anesthesiology trainees is lagging behind the demographic shift in the US.

Methods

We extracted data from the Accreditation Council for Graduate Medical Education (ACGME) graduate medical education Data Resource Book from 2012 to 2022. We performed a Chi-squared analysis of the demographic data of Anesthesiology residents and subspecialty fellows by race and ethnicity then compared to US census demographics & AAMC Matriculant Data File.

Results

Asian residents and fellows are overrepresented in nearly all categories, ie. Anesthesiology residency, Pediatric Anesthesia, Pain Medicine, Adult Cardiothoracic Anesthesia, Critical Care Medicine, and Colon & Rectal Surgery fellowship (all pp<0.001). Black, Hispanic, and Native American doctors are all underrepresented in Anesthesiology residency programs (p<0.001). At the fellowship level, Black candidates are underrepresented in Adult Cardiothoracic Anesthesia (p<.01), Pain Medicine (p<0.001), Pediatric Anesthesia (p<.05), and Critical Care (p<.001). Hispanic candidates are underrepresented in nearly all subspecialty programs: Colon & Rectal surgery (p<.001), Critical Care (p<.001), Obstetric Anesthesia (p<.05), Pediatric Anesthesia (p<.05), Pain Medicine (p<0.001), and Adult Cardiothoracic (p<.001).

Conclusion

The onus now lies with academic medical institutions to cultivate diversity by recruiting and retaining URiM trainees so that the field can better reflect the population and bridge the gap to healthcare equity.

目的 少数种族和少数族裔在疼痛评估和镇痛实施方面历来存在不平等现象,围手术期的结果也较差。要满足这些人群的需求,就需要一支同样多元化的医生队伍。尽管美国研究生医学教育认证委员会(ACGME)有意优先扩大和支持多元化的医师队伍,但URiM麻醉学受训人员的比例却落后于美国人口结构的变化。我们按种族和民族对麻醉学住院医师和亚专科研究员的人口统计学数据进行了卡方分析,然后与美国人口普查人口统计学数据& AAMC新生数据文件进行了比较。结果 在几乎所有类别中,亚裔住院医师和研究员的比例都过高,即麻醉学住院医师、小儿麻醉、疼痛医学、成人心胸麻醉、重症监护医学和结肠直肠外科研究员(均为 pp<0.001)。黑人、西班牙裔和美国本土医生在麻醉学住院医师培训项目中的比例均偏低(p<0.001)。在研究员级别,黑人候选人在成人心胸麻醉(p<.01)、疼痛医学(p<0.001)、儿科麻醉(p<.05)和重症监护(p<.001)方面的代表性不足。在几乎所有亚专科项目中,西班牙裔候选人的比例都偏低:结肠和直肠外科(p<.001)、重症监护(p<.001)、产科麻醉(p<.05)、儿科麻醉(p<.05)、疼痛科(p<0.001)和成人心胸科(p<.001)。结论学术医疗机构现在有责任通过招聘和留住 URiM 受训人员来培养多样性,从而使该领域能够更好地反映人口状况,缩小医疗保健公平方面的差距。
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引用次数: 0
Analysis of pancreatic cancer treatment and survival disparities in Florida throughout the Covid-19 pandemic 分析佛罗里达州在整个 Covid-19 大流行期间的胰腺癌治疗和存活差距。
IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.1016/j.jnma.2024.07.004
Guettchina Telisnor , Alexander Lim , Zhongyue Zhang , XiangYang Lou , Ibrahim Nassour , Ramzi G. Salloum , Sherise C. Rogers

Introduction

Pancreatic ductal adenocarcinoma (PDAC) is currently the third-leading cause of cancer-related death in the United States. African Americans (AAs) with PDAC have worse survival in comparison to other racial groups. The COVID-19 pandemic caused significant stress to the healthcare system. We aim to evaluate the pandemic's impact on already known disparities in newly diagnosed patients with PDAC in Florida.

Methods

This is a retrospective analysis of newly diagnosed patients with PDAC in the OneFlorida+ Data Trust based upon date of diagnosis: Pre-pandemic (01/01/2017- 09/30/2019), Transition (10/01/2019-02/28/2020), and Pandemic (03/1/2020-10/31/2020). Primary endpoints are time to treatment initiation and rate of surgery and secondary endpoint is survival time. Disparities due to age, sex, race, and income were also evaluated. Chi-squared or Fisher's exact test when necessary, Kruskal-Wallis test, and Kaplan-Meier analysis with log-rank test were performed to compare the differences between the comparative groups for categorical, quantitative, and survival outcomes, respectively. Multivariable regression analyses were conducted to estimate the effects of cofactors.

Results

934 patients with a median age of 67 years were included. There were 47.8% females and 52.2% males; 19.4% AA, 70.2% Caucasian, 10.4% Other race; median income was $53,551. While we observed a significant reduction in the diagnosis rate of new PDAC cases during the pandemic, there were no significant differences in demographic distributions among the three cohorts. Time to treatment did not significantly change from the pre-pandemic to the pandemic, and no difference was observed across all demographics. Rate of surgery increased significantly from the pre-pandemic (35.8%) to the pandemic (55.6%). AAs in the pre-pandemic cohort had a significantly lower rate of surgery of 25.0% compared to 41.7% in Caucasians. AAs, patients ≥ 67 years, and income < $53,000 had significantly higher hazards to death and shorter median survival time (mST).

Conclusions

While no differences in time to initial treatment are observed among the newly diagnosed PDAC patients, there remain significant disparities in the rate of surgery and overall survival. Observing a significant reduction in diagnosis rate and analyzing disparities can provide insight into the effect of a resource-restricting pandemic for patients with newly diagnosed PDAC.

简介:胰腺导管腺癌(PDAC)目前是美国癌症相关死亡的第三大原因。与其他种族群体相比,罹患 PDAC 的非裔美国人(AAs)的生存率较低。COVID-19 大流行给医疗保健系统造成了巨大压力。我们旨在评估大流行对佛罗里达州新诊断的 PDAC 患者中已知差异的影响:这是一项根据诊断日期对 OneFlorida+ 数据信托基金中新确诊的 PDAC 患者进行的回顾性分析:大流行前(01/01/2017- 09/30/2019)、过渡时期(10/01/2019-02/28/2020)和大流行时期(03/1/2020-10/31/2020)。主要终点是开始治疗的时间和手术率,次要终点是存活时间。还对年龄、性别、种族和收入造成的差异进行了评估。必要时采用卡方检验或费雪精确检验、Kruskal-Wallis 检验以及带有对数秩检验的 Kaplan-Meier 分析,分别比较比较组之间在分类、定量和生存结果方面的差异。此外,还进行了多变量回归分析,以估计辅助因素的影响:共纳入 934 名患者,中位年龄为 67 岁。其中女性占 47.8%,男性占 52.2%;19.4% 为 AA 族,70.2% 为白种人,10.4% 为其他种族;收入中位数为 53,551 美元。虽然我们观察到大流行期间 PDAC 新病例的诊断率明显下降,但三个组群的人口分布没有明显差异。从大流行前到大流行期间,治疗时间没有明显变化,而且在所有人口统计学特征中也没有观察到差异。从大流行前(35.8%)到大流行期间(55.6%),手术率明显增加。与白种人的 41.7% 相比,大流行前队列中的 AA 人的手术率明显较低,仅为 25.0%。AA、患者年龄≥67岁、收入低于53,000美元的患者死亡风险明显更高,中位生存时间(mST)也更短:结论:虽然新确诊的 PDAC 患者在接受初始治疗的时间上没有差异,但在手术率和总生存率上仍存在显著差异。通过观察诊断率的显著下降并分析差异,可以深入了解资源限制性大流行对新诊断的 PDAC 患者的影响。
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引用次数: 0
Severe Retiform Purpura with Cryoglobulinemia 伴有冷球蛋白血症的严重视网膜紫癜
IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.1016/j.jnma.2024.07.037
Ayomide Akinsooto MS, Katherine Smith MD, Sandra Osswald MD

Introduction

Mixed cryoglobulinemia is a rare systemic vasculitis characterized by the presence of cryoglobulins precipitating at low temperatures. These proteins can impede blood flow, leading to a variety of symptoms such as purpura, skin ulcers, and multi-organ impairment in severe cases. This condition presents diagnostic challenges due to its variable clinical presentation and relatively rare nature. This report details the case of a 41-year-old African American female with end-stage renal disease (ESRD) on peritoneal dialysis, initially suspected to have calciphylaxis, who was ultimately diagnosed with mixed cryoglobulinemia.

Methods

The patient's clinical presentation of bilateral thigh and breast wounds associated with severe pain, prompted a thorough clinical workup. Punch biopsies were taken from areas of new retiform purpura and examined with H&E and Von Kossa staining. Extensive lab work and serological analysis were obtained to help identify the underlying etiology.

Results

Biopsy examination was indicative of vasculopathy and comprehensive serologic analysis detected quantitative cryoglobulins, confirming non-infectious mixed cryoglobulinemia. Despite therapeutic interventions, the patient succumbed to complications associated with ESRD and secondary infections.

Conclusion

This case highlights the complexity of problems seen in ESRD patients on dialysis. When presented with a patient with ESRD with retiform purpura in fatty areas, calciphylaxis should be considered. If refractory or severe, a search for additional causes should be performed. Given its relatively rare nature, physicians must have a high index of suspicion to consider mixed cryoglobulinemia. Secondary complications in ESRD patients with retiform purpura are common, and continued surveillance for infectious complications is recommended.

导言混合型低温球蛋白血症是一种罕见的全身性血管炎,其特点是低温时会有低温球蛋白析出。这些蛋白会阻碍血流,导致各种症状,如紫癜、皮肤溃疡,严重时还会导致多器官功能损害。由于这种疾病的临床表现多变且相对罕见,因此给诊断带来了挑战。本报告详细介绍了一名 41 岁非裔美国女性患者的病例,该患者患有终末期肾病(ESRD),正在进行腹膜透析,起初被怀疑患有钙血症,但最终被诊断为混合型冷球蛋白血症。从新出现网状紫癜的部位进行了穿刺活检,并用 H&E 和 Von Kossa 染色法进行了检查。结果活检显示血管病变,综合血清学分析检测到定量的冷球蛋白,证实为非感染性混合型冷球蛋白血症。尽管采取了治疗措施,但患者还是死于 ESRD 相关并发症和继发性感染。当 ESRD 患者出现脂肪区网状紫癜时,应考虑钙化性紫癜。如果病情难治或严重,则应寻找其他原因。鉴于其相对罕见的性质,医生必须高度怀疑混合型冷球蛋白血症。患有网状紫癜的 ESRD 患者常见继发性并发症,建议继续监测感染性并发症。
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引用次数: 0
Assessing the Association Between School Victimization and Binge Drinking Among Sexual Minority Youth 评估性少数群体青少年中校园伤害与酗酒之间的关系
IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.1016/j.jnma.2024.07.090
Taylor Thaxton BA, MPH, Shahrzad Bazargan-Hejazi PhD

Introduction

Alcohol use among high school students, particularly high-risk drinking behaviors, are a significant public health concern. Substance use during adolescence is associated with increased risk of both acute and long-term adverse health outcomes. Sexual minority youth (SMY) are more likely to initiate alcohol use at a younger age and engage in binge drinking when compared to their heterosexual peers. There are also significant differences between the risky alcohol use behaviors among sexual minority identities. Recent research has suggested school-based victimization disproportionately impacts SMY and is associated with an increased risk of binge drinking. Through this study we hope to determine the association between binge drinking and sexual identity among high school students and assess if school-based victimization moderates this relationship

Methods

This cross sectional study utilized data from a nationally representative sample of United States high school students (n=26,675) collected in the 2017 and 2019 Youth Risk Behavior Survey. Logistic regression was used to assess the association between sexual minority identity and binge drinking. In addition, we tested for moderation of the relationship by school-based victimization.

Results

When compared to their heterosexual peers, bisexual female students were significantly more likely to report binge drinking within the past 30 days. School-based victimization moderate this association.

Conclusion

Bisexual females are at a higher risk of participating in binge drinking when compared to their heterosexual counterparts. Our results suggest interventions to reduce school-based victimization may play an important role in addressing risky drinking behavior in this population.

导言中学生饮酒,尤其是高风险饮酒行为,是一个重大的公共卫生问题。青少年时期使用药物与急性和长期不良健康后果的风险增加有关。与异性恋同龄人相比,性少数群体青少年(SMY)更有可能在较小的年龄开始饮酒,并出现暴饮行为。性少数群体身份之间的危险饮酒行为也存在明显差异。最近的研究表明,基于学校的伤害对性少数群体的影响尤为严重,并且与酗酒风险的增加有关。通过这项研究,我们希望确定高中生酗酒与性身份之间的关联,并评估基于学校的受害是否会调节这种关系方法这项横断面研究利用了2017年和2019年青少年风险行为调查中收集的具有全国代表性的美国高中生样本数据(n=26,675)。我们采用逻辑回归法评估了性少数群体身份与酗酒之间的关联。结果与异性恋同龄人相比,双性恋女学生在过去30天内报告酗酒的可能性明显更高。结论与异性恋学生相比,双性恋女性参与暴饮的风险更高。我们的研究结果表明,减少校园伤害的干预措施可能会在解决这一人群的危险饮酒行为方面发挥重要作用。
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引用次数: 0
Suicide-related mortality in cardiovascular disease in the United States from 1999 to 2019 1999 年至 2019 年美国心血管疾病中与自杀相关的死亡率。
IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.1016/j.jnma.2024.07.001
Kenyon Agrons , Vijay Nambi , Ramiro Salas , Abdul Mannan Khan Minhas

Introduction

Research has shown chronic diseases can be associated with suicide but there is limited data on suicide in cardiovascular disease (CVD). Given the substantial psychosocial, financial, quality of life, and health impact of CVD, we aimed to study suicide-related mortality in CVD.

Methods

We used Center for Disease Control Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) to access Multiple Cause of Death data from 1999 to 2019. Suicide and CVD related deaths in patients ≥ 25 years were identified. Proportionate suicide-related mortality (PSrM) was calculated as suicide-related deaths (listed with CVD) divided by all CVD-related deaths (irrespective of suicide) and reported as PSrM per 100,000 CVD-related deaths. Joinpoint regression was used to examine trend changes using annual percentage change (APC) overall and by sex, race/ethnicity, disease subtype, and age.

Results

Overall, PSrM in CVD increased from 62.8 in 1999 to 90.5 in 2019. The PSrM increased from 1999 to 2002 with an associated APC of 6.2 (95 % CI, 0.0 to 12.7), remained stable from 2002 to 2005, increased from 2005 to 2013 with an APC of 4.8 (95 % CI, 3.4 to 6.3), and decreased from 2013 to 2019 with an APC of -2.1 (95 % CI, -3.6 to -0.5). Among racial/ethnic groups, PSrM was highest in non-hispanic (NH) White (103.8), then Hispanic or Latino (63.6), and then NH Black or African American individuals (29.2). PSrM was highest in the 25–39 years age group (858), then 40–54 years (382.8), 55–69 years (146.2), 70–84 years (55.9), and then 85+ (17). PSrM initially increased in men with APC (3.1 until 2013), women (4.1 until 2014), NH White individuals (3.9 until 2013), Hispanic or Latino (3.5 until 2014), ages 40–54 years (2.9 until 2013), 55–69 years (6.0 until 2013), then stabilized or decreased. AAMR increased in NH Black or AA individuals APC (1.0) and 25–39 years APC (1.4) from 1999 to 2019.

Conclusion

PSrM in CVD peaked in the early 2010s, with varying differences across sex, racial/ethnic, and age groups. Further research is needed to understand disparities and develop preventive strategies.

导言:研究表明,慢性疾病可能与自杀有关,但有关心血管疾病(CVD)中自杀的数据却很有限。鉴于心血管疾病对社会心理、经济、生活质量和健康的重大影响,我们旨在研究心血管疾病中与自杀相关的死亡率:我们使用疾病控制中心流行病学研究广泛在线数据(CDC WONDER)获取了 1999 年至 2019 年的多死因数据。确定了年龄≥25岁的患者中与自杀和心血管疾病相关的死亡。自杀相关死亡率(PSrM)的计算方法是:自杀相关死亡(与心血管疾病并列)除以所有心血管疾病相关死亡(无论是否自杀),并以每 100,000 例心血管疾病相关死亡中的 PSrM 报告。采用连接点回归法,以年度百分比变化(APC)来检验总体趋势变化以及按性别、种族/民族、疾病亚型和年龄划分的趋势变化:总体而言,心血管疾病的 PSrM 从 1999 年的 62.8 上升至 2019 年的 90.5。1999年至2002年,PSrM有所上升,相关APC为6.2(95 % CI,0.0至12.7),2002年至2005年保持稳定,2005年至2013年有所上升,APC为4.8(95 % CI,3.4至6.3),2013年至2019年有所下降,APC为-2.1(95 % CI,-3.6至-0.5)。在种族/族裔群体中,非西班牙裔 (NH) 白人的 PSrM 最高(103.8),然后是西班牙裔或拉丁裔(63.6),然后是 NH 黑人或非裔美国人(29.2)。PSrM 在 25-39 岁年龄组(858 人)最高,然后是 40-54 岁(382.8 人)、55-69 岁(146.2 人)、70-84 岁(55.9 人)和 85 岁以上(17 人)。患有 APC 的男性(2013 年前为 3.1)、女性(2014 年前为 4.1)、新罕布什尔州白人(2013 年前为 3.9)、西班牙裔或拉丁裔(2014 年前为 3.5)、40-54 岁(2013 年前为 2.9)、55-69 岁(2013 年前为 6.0)的 PSrM 最初有所上升,随后趋于稳定或有所下降。从 1999 年到 2019 年,新罕布什尔州黑人或 AA 人 APC(1.0)和 25-39 岁 APC(1.4)的 AAMR 有所上升:心血管疾病的 PSrM 在 2010 年代初达到顶峰,不同性别、种族/族裔和年龄组的差异各不相同。需要进一步研究以了解差异并制定预防策略。
{"title":"Suicide-related mortality in cardiovascular disease in the United States from 1999 to 2019","authors":"Kenyon Agrons ,&nbsp;Vijay Nambi ,&nbsp;Ramiro Salas ,&nbsp;Abdul Mannan Khan Minhas","doi":"10.1016/j.jnma.2024.07.001","DOIUrl":"10.1016/j.jnma.2024.07.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Research has shown chronic diseases can be associated with suicide but there is limited data on suicide in cardiovascular disease (CVD). Given the substantial psychosocial, financial, quality of life, and health impact of CVD, we aimed to study suicide-related mortality in CVD.</p></div><div><h3>Methods</h3><p>We used Center for Disease Control Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) to access Multiple Cause of Death data from 1999 to 2019. Suicide and CVD related deaths in patients ≥ 25 years were identified. Proportionate suicide-related mortality (PSrM) was calculated as suicide-related deaths (listed with CVD) divided by all CVD-related deaths (irrespective of suicide) and reported as PSrM per 100,000 CVD-related deaths. Joinpoint regression was used to examine trend changes using annual percentage change (APC) overall and by sex, race/ethnicity, disease subtype, and age.</p></div><div><h3>Results</h3><p>Overall, PSrM in CVD increased from 62.8 in 1999 to 90.5 in 2019. The PSrM increased from 1999 to 2002 with an associated APC of 6.2 (95 % CI, 0.0 to 12.7), remained stable from 2002 to 2005, increased from 2005 to 2013 with an APC of 4.8 (95 % CI, 3.4 to 6.3), and decreased from 2013 to 2019 with an APC of -2.1 (95 % CI, -3.6 to -0.5). Among racial/ethnic groups, PSrM was highest in non-hispanic (NH) White (103.8), then Hispanic or Latino (63.6), and then NH Black or African American individuals (29.2). PSrM was highest in the 25–39 years age group (858), then 40–54 years (382.8), 55–69 years (146.2), 70–84 years (55.9), and then 85+ (17). PSrM initially increased in men with APC (3.1 until 2013), women (4.1 until 2014), NH White individuals (3.9 until 2013), Hispanic or Latino (3.5 until 2014), ages 40–54 years (2.9 until 2013), 55–69 years (6.0 until 2013), then stabilized or decreased. AAMR increased in NH Black or AA individuals APC (1.0) and 25–39 years APC (1.4) from 1999 to 2019.</p></div><div><h3>Conclusion</h3><p>PSrM in CVD peaked in the early 2010s, with varying differences across sex, racial/ethnic, and age groups. Further research is needed to understand disparities and develop preventive strategies.</p></div>","PeriodicalId":17369,"journal":{"name":"Journal of the National Medical Association","volume":"116 4","pages":"Pages 378-389"},"PeriodicalIF":2.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141891488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between Live Births and CVD among African American Women in Jackson Heart Study 杰克逊心脏研究》中非裔美国妇女的活产与心血管疾病之间的关系
IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.1016/j.jnma.2024.07.021
Elizabeth A.K. Jones MPH, Dr. Keith Norris MD, PhD, Dr. Brenda Jenkins PhD, Dr. Clifton Addison PhD, Dr. Marinelle Payton MD, PhD, MS, MPH

Background

Previous studies have reported mixed results on the relationship between live births and cardiovascular disease among African American females, with few controlling for an inclusive list of major cardiovascular disease (CVD) risk factors and/or including a large population of African American female participants.

Methods

Data was from 3367 African American women, 21 and older, in the Jackson Heart Study. Myocardial Infraction (MI), Self-reported history of cardiac procedures, Coronary Heart Disease Status/History, Self-reported history of Carotid Angioplasty, Cardiovascular Disease history, and Heart Failure History were obtained from 2000 to 2004 interviews. Live births were self-reported. Chi-square test indicated a significant association between live births and the presence of CVD (p =.000). Logistic regression estimated the relationship between live births and cardiovascular events, adjusting for major cardiovascular risk factors.

Results

After adjusting for hypertension status, current smoking status, cholesterol status, diabetes status, family history of heart diseases (mother), family history of heart disease (father), age, frequency of alcohol use in the past 12 months, and the average number of drinks per week in the past 12 months, there was no longer a significant relationship between live births and the risk of CVD (AOR 1.012, 95% CI, 1.009-1.015, p=.895).

Conclusion

The unadjusted significant relationship between live births and CVD events disappeared after adjusting for major CVD risk factors, which suggests that an association between live births and CVD is indirect and based on the distribution of CVD risk factors.

背景以前的研究报告显示,非裔美国女性活产与心血管疾病之间的关系结果不一,很少有研究控制了主要心血管疾病(CVD)风险因素和/或包括大量非裔美国女性参与者。心肌梗死(MI)、自我报告的心脏手术史、冠心病状况/病史、自我报告的颈动脉血管成形术史、心血管疾病史和心力衰竭史均来自 2000 年至 2004 年的访谈。活产情况为自报。卡方检验(Chi-square test)表明,活产与是否患有心血管疾病之间存在显著关联(p =.000)。结果在调整了高血压状况、当前吸烟状况、胆固醇状况、糖尿病状况、心脏病家族史(母亲)、心脏病家族史(父亲)、年龄、过去 12 个月中饮酒频率以及过去 12 个月中每周平均饮酒次数后,活产与心血管疾病风险之间不再存在显著关系(AOR 1.012,95% CI,1.009-1.015,p=.895)。结论在调整主要心血管疾病风险因素后,活产与心血管疾病事件之间未经调整的显著关系消失了,这表明活产与心血管疾病之间的关系是间接的,并且是基于心血管疾病风险因素的分布。
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引用次数: 0
Gestational Diabetes Mellitus Prevalence and Correlates in North West, Nigeria 尼日利亚西北部地区妊娠糖尿病发病率及其相关因素
IF 2.5 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-08-01 DOI: 10.1016/j.jnma.2024.07.071
Ashiru Argungu Ladan MBBS, MPH, FWACS, Oche Mansur Oche, Kahinde Joseph Awosan, Aisha Nana Adamu, Umar Augie Ibrahim, Asma'u Husna Ibrahim, Bashir Hashim, Ja'afarAliyu Musa

Introduction

Gestational diabetes mellitus (GDM) is one of the most common medical complications of pregnancy. It is a condition in which women without previously diagnosed diabetes mellitus exhibit high blood glucose levels during pregnancy. Hyperglycemia in pregnancy results in both maternal and fetal complications. The prevalence is rising worldwide. The study aimed to determine the prevalence of GDM and its correlates among women attending ANC at FMC Birnin Kebbi.

Methodology

A cross sectional study was carried out among 130 women attending ANC at FMC, Birnin Kebbi. An interviewer administered semi-structured questionnaire was used to obtain the biodata and other relevant information which were imputed into an SPSS computer statistical software version 20 and analyzed.

Results

The mean age of study participants was 27.4±4.5 years. Awareness of DM was high (90%), while that of GDM was low 41%. The major sources of information were friends/ neighbors (35%). However, only 35.2% had overall good knowledge for GDM. The prevalence of GDM and DM in pregnancy was 10% and 3.8% respectively. The major risk factors for GDM identified were; age, obesity and family of type 2 DM. The common complications identified associated from GDM/DM were; polyhydramnios, intrauterine fetal death and increase risk of Caesarean section.

Conclusion

From the study the prevalence of GDM is increasing with general poor knowledge of the condition. Hence, more public enlightenment programs are needed to improve the level of awareness among the populace and regular screening in all health facilities among the ANC patients.

导言妊娠糖尿病(GDM)是最常见的妊娠并发症之一。妊娠期糖尿病是指未确诊糖尿病的妇女在妊娠期间出现高血糖。妊娠期高血糖会导致母体和胎儿并发症。这种疾病在全世界的发病率都在上升。本研究旨在确定在比尔宁-凯比市妇幼保健院(FMC Birnin Kebbi)接受产前检查的妇女中 GDM 的患病率及其相关因素。方法 对在比尔宁-凯比市妇幼保健院(FMC Birnin Kebbi)接受产前检查的 130 名妇女进行了横断面研究。采用访谈式半结构化问卷调查法获得生物数据和其他相关信息,并将其输入 SPSS 计算机统计软件 20 版进行分析。结果研究参与者的平均年龄为(27.4±4.5)岁。对 DM 的认知度较高(90%),而对 GDM 的认知度较低,仅为 41%。信息的主要来源是朋友/邻居(35%)。然而,只有 35.2% 的人对 GDM 有全面的了解。GDM 和妊娠期糖尿病的发病率分别为 10%和 3.8%。GDM 的主要风险因素包括:年龄、肥胖和 2 型糖尿病家族史。与 GDM/DM 相关的常见并发症有:多胎畸形、胎儿宫内死亡和剖腹产风险增加。因此,需要开展更多的公共启蒙计划,以提高民众的认识水平,并在所有医疗机构对产前检查患者进行定期筛查。
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引用次数: 0
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