We have impression that the insurance reimbursement program for handling in-patient care services offered by hospital pharmacists in Japan has been established as an important routine work.Accrdingly, we felt the need to understand clearly the doctors' requirements regarding clinical pharmacy services offered in Hirosaki University Hospital. We therefore made a survey to assess the doctors' idea for clinical pharmacy services in our hospital because we recognized that they should be smoothly introduced in our hospital. Of 259 questionnaires distributed to doctors in Hirosaki University, usable responese of 65.6 % were returned. Although almost all doctors (85.3%) were unaware of the insurance reimbursement program system in Japan, nearly all of them (99.4%) recognized the necessity of providing medicational instruction concerning drug therapy. Almost all doctors (79.9%) thought that the clinical pharmacy services offered by pharmacists were needed for effective clinical drug therapy whereas 20.1 % of them responded that they were unnecessary. Obtaining information on the adverse effects of drugs and on drug interactions constituted the most important request for the clinical pharmacy services from our hospital doctors. From the results of our survey, it was found that almost all of our hospital doctors had their comprehenision of clinical pharmacy services offered by pharmacists.
{"title":"薬剤管理指導料(600点)認可に向けてのアンケート調査結果(医師部門)","authors":"正 大久保, 秀紀 野呂, 学 須野, 正純 工藤, 司 宇野, 律子 下山, 祥子 藤田, 昭良 大泉, 健 桜田, 和信 菅原","doi":"10.5649/jjphcs1975.22.246","DOIUrl":"https://doi.org/10.5649/jjphcs1975.22.246","url":null,"abstract":"We have impression that the insurance reimbursement program for handling in-patient care services offered by hospital pharmacists in Japan has been established as an important routine work.Accrdingly, we felt the need to understand clearly the doctors' requirements regarding clinical pharmacy services offered in Hirosaki University Hospital. We therefore made a survey to assess the doctors' idea for clinical pharmacy services in our hospital because we recognized that they should be smoothly introduced in our hospital. Of 259 questionnaires distributed to doctors in Hirosaki University, usable responese of 65.6 % were returned. Although almost all doctors (85.3%) were unaware of the insurance reimbursement program system in Japan, nearly all of them (99.4%) recognized the necessity of providing medicational instruction concerning drug therapy. Almost all doctors (79.9%) thought that the clinical pharmacy services offered by pharmacists were needed for effective clinical drug therapy whereas 20.1 % of them responded that they were unnecessary. Obtaining information on the adverse effects of drugs and on drug interactions constituted the most important request for the clinical pharmacy services from our hospital doctors. From the results of our survey, it was found that almost all of our hospital doctors had their comprehenision of clinical pharmacy services offered by pharmacists.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"29 1","pages":"246-255"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74911855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-12-10DOI: 10.5649/JJPHCS1975.21.483
M. Myotoku, T. Suyama, Hisayuki Haji
{"title":"Examination of Utility Kremezin as an Antidote for Acute Drug Poisoning","authors":"M. Myotoku, T. Suyama, Hisayuki Haji","doi":"10.5649/JJPHCS1975.21.483","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.21.483","url":null,"abstract":"","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"23 1","pages":"483-487"},"PeriodicalIF":0.0,"publicationDate":"1995-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73015885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-10-10DOI: 10.5649/JJPHCS1975.21.454
M. Myotoku, Hiroko Tai, J. Takeuchi, Hisayuki Haji
To prescribe drugs or check a prescription, it is very important to understand the contraindications. We developed an original drug information system utilizing commercialy available application software. On the base of this system, we made a list of drugs sequenced due to each contraindication and a list of drugs contraindicated due to drug interactions for combination use. Thus, this list enables us to save times in our searching for the information.
{"title":"Preparation of a List Drugs Sequenced due to the Contraindications of Each and a List of Drugs Contraindicated due to Drug Interactions for Combination Use at Municipal Ikeda Hospital.","authors":"M. Myotoku, Hiroko Tai, J. Takeuchi, Hisayuki Haji","doi":"10.5649/JJPHCS1975.21.454","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.21.454","url":null,"abstract":"To prescribe drugs or check a prescription, it is very important to understand the contraindications. We developed an original drug information system utilizing commercialy available application software. On the base of this system, we made a list of drugs sequenced due to each contraindication and a list of drugs contraindicated due to drug interactions for combination use. Thus, this list enables us to save times in our searching for the information.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"8 1","pages":"454-461"},"PeriodicalIF":0.0,"publicationDate":"1995-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72898217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A solution comprising sodium azulene sulfonate, lidocaine hydrochloride and Elase (fibrinolysin and DNase) is used as a gargle to relieve the pain after the operation of malignant tumor of the head and neck and to remove exudata from the inflammed part.Azulene sufonate and lidocaine in Azunol·Elase·Xylocaine gargle (AEXG) were stable when kept at 5°±1, 20°±1 and 30°±1 over a 14-day period. However, the activities of fibrinolysin and DNase in AEXG rapidly decreased even at 5°. These results demonstrated that AEXG is unstable and should be prepared just prior to use. However, AEXG produced a remarkable pain relieving effect with few adverse reactions. And AEXG is clinically evaluated highly in spite of its unstability.
{"title":"院内製剤アズノール・エレース・キシロカイン含嗽液 (AEXG) の安定性と臨床適用","authors":"伸浩 安野, 茂和 渡辺, 進 神田, 純子 木津, 雅勇 土屋, 篤彦 西谷, 秀樹 小野, 一洋 今井, 石尾 健一郎, 壽孝 飯沼","doi":"10.5649/JJPHCS1975.21.327","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.21.327","url":null,"abstract":"A solution comprising sodium azulene sulfonate, lidocaine hydrochloride and Elase (fibrinolysin and DNase) is used as a gargle to relieve the pain after the operation of malignant tumor of the head and neck and to remove exudata from the inflammed part.Azulene sufonate and lidocaine in Azunol·Elase·Xylocaine gargle (AEXG) were stable when kept at 5°±1, 20°±1 and 30°±1 over a 14-day period. However, the activities of fibrinolysin and DNase in AEXG rapidly decreased even at 5°. These results demonstrated that AEXG is unstable and should be prepared just prior to use. However, AEXG produced a remarkable pain relieving effect with few adverse reactions. And AEXG is clinically evaluated highly in spite of its unstability.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"99 1","pages":"327-334"},"PeriodicalIF":0.0,"publicationDate":"1995-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78873764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-06-10DOI: 10.5649/JJPHCS1975.21.191
Keiko Butatsu, Tomoko Takamatsu, M. Sugihara, M. Ohbuchi, K. Fukumuro
{"title":"Study on Applicability of a Database for Adverse Reaction Literature in the DI Room and Evaluation of Its Contents","authors":"Keiko Butatsu, Tomoko Takamatsu, M. Sugihara, M. Ohbuchi, K. Fukumuro","doi":"10.5649/JJPHCS1975.21.191","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.21.191","url":null,"abstract":"","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"45 1","pages":"191-199"},"PeriodicalIF":0.0,"publicationDate":"1995-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82680650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-04-10DOI: 10.5649/JJPHCS1975.21.109
Masayuki Ichisawa, Ikuko Sasaki, M. Iwata, T. Takizawa, Shoichi Shirotake
THEODUR®syrup (TDRsyr) is the first liquid dosage form of a long-acting theophylline in Japan. The dosage form design, a matrix form containing theophylline, is suspended in Dsorbitol solution having a high viscosity. To ensure its efficacy, it is necessary to develop precise dispensing technigue. The content of theophylline in TDRsyr was measured by highperformance liquid chromatography (HPLC) after methanol extraction. The concentration of theophylline, after being shaken in a container of TDRsyr (20mg/ml), was 101.5w/v% of the indication value. And its coefficient of variation was 0.7%(n=5), conforming that the quantitative method has good reproducibility. For reliable dispensing, shaking the commercial TDRsyr for longer than 40 minutes is required, and shaking must be done in an up-and-down manner 8 times (8 cycles) per second. Moreover, prior taking it as a dosage, it must be shaken for longer than 2 minutes for 4 cycles per second. When a patient measures out the TDRsyr dosage, a measuring cup is found to be more suitable for reliable dispensing than a small pipette.
{"title":"Evaluation of a Sustained-release Theophylline Liquid Medicine on Dispensing and Patient-teaching","authors":"Masayuki Ichisawa, Ikuko Sasaki, M. Iwata, T. Takizawa, Shoichi Shirotake","doi":"10.5649/JJPHCS1975.21.109","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.21.109","url":null,"abstract":"THEODUR®syrup (TDRsyr) is the first liquid dosage form of a long-acting theophylline in Japan. The dosage form design, a matrix form containing theophylline, is suspended in Dsorbitol solution having a high viscosity. To ensure its efficacy, it is necessary to develop precise dispensing technigue. The content of theophylline in TDRsyr was measured by highperformance liquid chromatography (HPLC) after methanol extraction. The concentration of theophylline, after being shaken in a container of TDRsyr (20mg/ml), was 101.5w/v% of the indication value. And its coefficient of variation was 0.7%(n=5), conforming that the quantitative method has good reproducibility. For reliable dispensing, shaking the commercial TDRsyr for longer than 40 minutes is required, and shaking must be done in an up-and-down manner 8 times (8 cycles) per second. Moreover, prior taking it as a dosage, it must be shaken for longer than 2 minutes for 4 cycles per second. When a patient measures out the TDRsyr dosage, a measuring cup is found to be more suitable for reliable dispensing than a small pipette.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"46 1","pages":"109-114"},"PeriodicalIF":0.0,"publicationDate":"1995-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80867730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Study of Computer Literature Searching Among Drug Information. A Comparative Study of the Difference in Time Frame for an Article to be Indexed in the CD-ROM and ON-LINE MEDLINE Systems.","authors":"Futagami Koujiro, 二神 幸次郎, 敦子 西山口, Nishiyamaguchi Atsuko, 一雄 朝倉, Asakura Hajime, 光郎 深川, Fukagawa Mitsuro, 誠 川重, Kawashige Makoto, 健司 大坪, Otsubo Kenji, 敏信 青山, Aoyama Toshinobu","doi":"10.5649/JJPHCS1975.21.70","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.21.70","url":null,"abstract":"","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"232 1","pages":"70-78"},"PeriodicalIF":0.0,"publicationDate":"1995-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86691919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1994-10-20DOI: 10.5649/JJPHCS1975.20.442
M. Muranaka, Noboru Nagai, Makoto Watanabe, H. Hata, T. Kamon, Y. Taniguchi, K. Tabata, Katsuhisa Abe, H. Ogawa, S. Nakayama, Takehiko Furukawa, Masashi Oshibe, Hiroshi Suzuki, Chikara Iwatate, C. Mizuochi, H. Obata, Kinzi Wahara, Y. Komiya, Tetsu Takahashi, T. Sonoda, M. Hayakawa, Akio Tanaka, K. Takenaka
Investigated in seven Kosei-nenkin Hospitals (member hospitals of the Employee's Pension Insurance Society), were 24, 498 prescriptions given to outpatients. These were given to 21, 552 outpatients who were instructed to take medication on October 30, 1990 according to the prescriptions regardless of the various periods during which they have taken the drug. These prescriptions were accumulated from October 1 to October 30, 1990. In addition, 2, 021 patients who consulted the hospital's outpatient clinics on October 30, 1990 for treatment of their illnesses were interviewed at the dispensary to find out whether they were taking drugs prescribed by other medical facilities.The results were as follows:1) 549 (27.2%) of 2, 021 patients were taking drugs given by either other medical facilities or pharmacies.2) The mean number of drugs prescribed in the 24, 498 prescriptions was 3.8 per patient. The number of drugs in anyone prescription was increased along with the age of the patient.3) Overlapping of drugs among prescriptions were 724 (3.0%) cases in 24, 498.4) 1, 706 (7.9%) of 21, 552 patients were given prescriptions containing a combination of drugs exhibiting a possible drug-to-drug interaction.5) 840 (3.9%) of 21, 552 patients were instructed by doctors to take more than 10 kinds of drugs within the same day. The mean number of their illnesses was 4.5 (1-12) and that of drugs per one illness was 2.6.
{"title":"Investigation of Prescriptions Given to Outpatients in Seven Kosei-nenkin Hospitals","authors":"M. Muranaka, Noboru Nagai, Makoto Watanabe, H. Hata, T. Kamon, Y. Taniguchi, K. Tabata, Katsuhisa Abe, H. Ogawa, S. Nakayama, Takehiko Furukawa, Masashi Oshibe, Hiroshi Suzuki, Chikara Iwatate, C. Mizuochi, H. Obata, Kinzi Wahara, Y. Komiya, Tetsu Takahashi, T. Sonoda, M. Hayakawa, Akio Tanaka, K. Takenaka","doi":"10.5649/JJPHCS1975.20.442","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.20.442","url":null,"abstract":"Investigated in seven Kosei-nenkin Hospitals (member hospitals of the Employee's Pension Insurance Society), were 24, 498 prescriptions given to outpatients. These were given to 21, 552 outpatients who were instructed to take medication on October 30, 1990 according to the prescriptions regardless of the various periods during which they have taken the drug. These prescriptions were accumulated from October 1 to October 30, 1990. In addition, 2, 021 patients who consulted the hospital's outpatient clinics on October 30, 1990 for treatment of their illnesses were interviewed at the dispensary to find out whether they were taking drugs prescribed by other medical facilities.The results were as follows:1) 549 (27.2%) of 2, 021 patients were taking drugs given by either other medical facilities or pharmacies.2) The mean number of drugs prescribed in the 24, 498 prescriptions was 3.8 per patient. The number of drugs in anyone prescription was increased along with the age of the patient.3) Overlapping of drugs among prescriptions were 724 (3.0%) cases in 24, 498.4) 1, 706 (7.9%) of 21, 552 patients were given prescriptions containing a combination of drugs exhibiting a possible drug-to-drug interaction.5) 840 (3.9%) of 21, 552 patients were instructed by doctors to take more than 10 kinds of drugs within the same day. The mean number of their illnesses was 4.5 (1-12) and that of drugs per one illness was 2.6.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"86 1","pages":"442-453"},"PeriodicalIF":0.0,"publicationDate":"1994-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78075234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1994-08-20DOI: 10.5649/JJPHCS1975.20.315
S. Miyamoto, Y. Kohda, Masaru Suzuki, E. Sagara
The bioavailability of phenytoin is well known to be dependent on the dosage forms as is the fact that ground tablets of phenytoin are often ordered instead of the powdered form in doctorwritten prescriptions. Studied in the present study was weight loss of the drug resulting from the dispensing process and adherence to the package.Used as model forms were three dosage forms of phenytoin: ground tablets, fine granules and powder. Simulative dispensing was performed using the conventional method in which tablets were ground with excipients, mixed with a mortar and pestle, and divided and packaged employing two kinds of packaging machines for dispensing.The extent of total weight in loss was dependent neither on the types of packaging machines, nor on the dosage forms of phenytoin except for ground tablets. For ground tablets, a large weight loss was observed in the dispensing process, with this phenomenon being caused by splashing in the packaging process. Observed with fine granules and powder was a small weight loss relative to the dispensing process and a large one involving adherence to the package. The total loss in dispensing and package adherence was found to be 6% regardless of the phenytoin dosage form.We conclude that fine granules in the powdered form of phenytoin are the most suitable dosage form because of the compositis equivalent bioavailability to the tablet form and its only slight loss in weight during the dispensing process.
{"title":"Drug-Loss in Dispensing Process and Adhering to the Package : Phenytoin Products as Model Dosage Forms","authors":"S. Miyamoto, Y. Kohda, Masaru Suzuki, E. Sagara","doi":"10.5649/JJPHCS1975.20.315","DOIUrl":"https://doi.org/10.5649/JJPHCS1975.20.315","url":null,"abstract":"The bioavailability of phenytoin is well known to be dependent on the dosage forms as is the fact that ground tablets of phenytoin are often ordered instead of the powdered form in doctorwritten prescriptions. Studied in the present study was weight loss of the drug resulting from the dispensing process and adherence to the package.Used as model forms were three dosage forms of phenytoin: ground tablets, fine granules and powder. Simulative dispensing was performed using the conventional method in which tablets were ground with excipients, mixed with a mortar and pestle, and divided and packaged employing two kinds of packaging machines for dispensing.The extent of total weight in loss was dependent neither on the types of packaging machines, nor on the dosage forms of phenytoin except for ground tablets. For ground tablets, a large weight loss was observed in the dispensing process, with this phenomenon being caused by splashing in the packaging process. Observed with fine granules and powder was a small weight loss relative to the dispensing process and a large one involving adherence to the package. The total loss in dispensing and package adherence was found to be 6% regardless of the phenytoin dosage form.We conclude that fine granules in the powdered form of phenytoin are the most suitable dosage form because of the compositis equivalent bioavailability to the tablet form and its only slight loss in weight during the dispensing process.","PeriodicalId":17399,"journal":{"name":"Journal of the Nippon Hospital Pharmacists Association","volume":"242 1","pages":"315-320"},"PeriodicalIF":0.0,"publicationDate":"1994-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76317231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：