Pub Date : 2016-12-30DOI: 10.15230/SCSK.2016.42.4.311
Chung Park, Jong-Min Han
Kava (Piper methysticum, P. methysticum) is used as traditional herbal medicine for urogenital diseases, rheumatisms, gastrointestinal problems, respiratory irritations, and pulmonary pains. We identified a flavokavain C (FKC) from P. methysticum, which showed anti-inflammatory activity on nuclear factor κB (NF-κB)-dependent nitric oxide (NO) production and expression of inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-induced RAW264.7 macrophages. FKC inhibited accumulation of reactive oxygen species (ROS), such as hydrogen peroxide, and was able to dose-dependently reduce the LPS-induced NO production and the expression of various inflammation-associated genes (iNOS, IL-1β, IL-6) through inhibition of NF-κB and MAPKs (ERK and JNK). In conclusion, these results indicate that FKC may have the potential to prevent inflammation process including NF-κB and MAPKs pathways, and it could be applicable to functional cosmetics for anti-inflammation and antioxidant properties.
{"title":"Anti-inflammatory Effects of Flavokavain C from Kava (Piper methysticum) Root in the LPS-induced Macrophages","authors":"Chung Park, Jong-Min Han","doi":"10.15230/SCSK.2016.42.4.311","DOIUrl":"https://doi.org/10.15230/SCSK.2016.42.4.311","url":null,"abstract":"Kava (Piper methysticum, P. methysticum) is used as traditional herbal medicine for urogenital diseases, rheumatisms, gastrointestinal problems, respiratory irritations, and pulmonary pains. We identified a flavokavain C (FKC) from P. methysticum, which showed anti-inflammatory activity on nuclear factor κB (NF-κB)-dependent nitric oxide (NO) production and expression of inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-induced RAW264.7 macrophages. FKC inhibited accumulation of reactive oxygen species (ROS), such as hydrogen peroxide, and was able to dose-dependently reduce the LPS-induced NO production and the expression of various inflammation-associated genes (iNOS, IL-1β, IL-6) through inhibition of NF-κB and MAPKs (ERK and JNK). In conclusion, these results indicate that FKC may have the potential to prevent inflammation process including NF-κB and MAPKs pathways, and it could be applicable to functional cosmetics for anti-inflammation and antioxidant properties.","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"14 1","pages":"311-320"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87579167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-30DOI: 10.15230/SCSK.2016.42.4.343
Sung Hoon Lee, I. Bae, D. Min, Hyoung-june Kim, N. Park, Jinhyu Choi, J. Shin, Eun Ju Kim, H. Lee
제주용암해수는 미네랄과 영양염류가 풍부한 물로 제주만이 보유한 지하수자원이다. 본 연구의 목적은 제주용암해수의 피부 보습효과를 확인하기 위한 것이다. 피부의 건조함을 막고 수분을 유지하기 위해서는 표피층의 장벽기능이 정상적으로 기능하고, 표피층 내 수분의 유지와 이동이 원활히 이루어져야 한다. 제주용암...
{"title":"Skin Hydration Effect of Jeju Lava Sea Water","authors":"Sung Hoon Lee, I. Bae, D. Min, Hyoung-june Kim, N. Park, Jinhyu Choi, J. Shin, Eun Ju Kim, H. Lee","doi":"10.15230/SCSK.2016.42.4.343","DOIUrl":"https://doi.org/10.15230/SCSK.2016.42.4.343","url":null,"abstract":"제주용암해수는 미네랄과 영양염류가 풍부한 물로 제주만이 보유한 지하수자원이다. 본 연구의 목적은 제주용암해수의 피부 보습효과를 확인하기 위한 것이다. 피부의 건조함을 막고 수분을 유지하기 위해서는 표피층의 장벽기능이 정상적으로 기능하고, 표피층 내 수분의 유지와 이동이 원활히 이루어져야 한다. 제주용암...","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"96 1","pages":"343-349"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89158309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Study on the Anti-wrinkle Activities of Sesamum indicum L. Ethanol Extracts on CCD-986sk","authors":"Dahye Joo, Dan-Hee Yoo, Jinyoung Lee","doi":"10.15230/SCSK.2016.42.4.377","DOIUrl":"https://doi.org/10.15230/SCSK.2016.42.4.377","url":null,"abstract":"본 연구에서는 참깨 추출물의 주름개선 화장품 원료로의 가능성을 확인하기 위하여, 참깨의 70% 에탄올 추출물을 제조하여, 엘라스타제 저해능, 콜라게나제 저해능, matrixmetallopoteinases (MMPs)의 단백질, mRNA 발현 저해 효능을 측정하였다. Elastase와 collagenase 저해활성은 $1000{mu}g/mL$ 농도에서 각각 37.8%...","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"130 1","pages":"377-385"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83450091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-30DOI: 10.15230/SCSK.2016.42.4.329
Mi‐Sun Kim, Y. Choi, Sun Gyoo Park, C. Lee, Sang Hwa Lee
진피 상층부 모세혈관은 젊은 사람에 비해 노인에서 그 수와 크기가 감소되어 있어 피부에서 모세혈관이 차지하는 비율이 나이에 따라 급격히 낮아진다. 연교는 물푸레나무과에 속하는 개나리 열매를 건조한 것으로 주로 염증성 또는 항균성 질환에 오랫동안 사용되어져온 약재로서 지금까지 피부 혈관신생과 관련된 효능은...
{"title":"Forsythiae Fructus Induces VEGF Production via p38 MAPK Activation in Human Keratinocytes","authors":"Mi‐Sun Kim, Y. Choi, Sun Gyoo Park, C. Lee, Sang Hwa Lee","doi":"10.15230/SCSK.2016.42.4.329","DOIUrl":"https://doi.org/10.15230/SCSK.2016.42.4.329","url":null,"abstract":"진피 상층부 모세혈관은 젊은 사람에 비해 노인에서 그 수와 크기가 감소되어 있어 피부에서 모세혈관이 차지하는 비율이 나이에 따라 급격히 낮아진다. 연교는 물푸레나무과에 속하는 개나리 열매를 건조한 것으로 주로 염증성 또는 항균성 질환에 오랫동안 사용되어져온 약재로서 지금까지 피부 혈관신생과 관련된 효능은...","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"4 1","pages":"329-336"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79142607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-30DOI: 10.15230/SCSK.2016.42.4.359
Do Yoon Kim, H. Yu, D. Hwang, Sang-Hee Jang, Hwan Myung Lee
: Exosome, a small vesicle secreted from cells, has diverse functions depending on cell origins and tissue types and plays a important role in cell viability and intercellular communication. Recently, many researchers have demon-strated the use of exosomes for the treatment of cancers and immune diseases, and the development of diagnostic biomarker. However, the secretion mechanism of exosome from skin cell and its physiological functions in skin remain unclear. Thus, this study aimed to explore whether keratinocyte-derived exosome affects proliferation and migration in HaCaTs. Exosomes were isolated from HaCaTs by ExoQuick-TC and then boiled or unbolied. Boiled and unboiled exosome induced proliferation in HaCaTs in a dose-dependant manner (0.1 ∼ 20 µ g/mL), respectively. Boiled and unboiled exosome at concentration of 20 µ g/mL increased proliferation level in HaCaTs by 186.96 ± 3.87% and 193.48 ± 10.48% compared with control group. Unboiled exosome stimulated migration in HaCaTs in a dose-dependent manner (0.1 ∼ 20 µ g/mL), which reached a maxium at concentration of 20 µ g/mL (179.39 ± 4.89% of control), but boiled exosome did not affect HaCaT migration. In addition, unboiled exosome (0.1 ∼ 20 µ g/mL) dose-dependently stimulated sprout outgrowth in HaCats. These results demonstrate that in exosome from HaCaTs, heat-stable components such as lipid may induce HaCaT proliferation and heat-unstable components such as protein may stimulate migration and sprout outgrowth in HaCaTs, thereby leading to reepithelialization and skin-wound healing activities. It is concluded that exosomes from HaCaTs may be used as cosmetic materials.
{"title":"Effect of Keratinocyte Derived Exosome on Proliferation and Migration on Human Skin Keratinocyte","authors":"Do Yoon Kim, H. Yu, D. Hwang, Sang-Hee Jang, Hwan Myung Lee","doi":"10.15230/SCSK.2016.42.4.359","DOIUrl":"https://doi.org/10.15230/SCSK.2016.42.4.359","url":null,"abstract":": Exosome, a small vesicle secreted from cells, has diverse functions depending on cell origins and tissue types and plays a important role in cell viability and intercellular communication. Recently, many researchers have demon-strated the use of exosomes for the treatment of cancers and immune diseases, and the development of diagnostic biomarker. However, the secretion mechanism of exosome from skin cell and its physiological functions in skin remain unclear. Thus, this study aimed to explore whether keratinocyte-derived exosome affects proliferation and migration in HaCaTs. Exosomes were isolated from HaCaTs by ExoQuick-TC and then boiled or unbolied. Boiled and unboiled exosome induced proliferation in HaCaTs in a dose-dependant manner (0.1 ∼ 20 µ g/mL), respectively. Boiled and unboiled exosome at concentration of 20 µ g/mL increased proliferation level in HaCaTs by 186.96 ± 3.87% and 193.48 ± 10.48% compared with control group. Unboiled exosome stimulated migration in HaCaTs in a dose-dependent manner (0.1 ∼ 20 µ g/mL), which reached a maxium at concentration of 20 µ g/mL (179.39 ± 4.89% of control), but boiled exosome did not affect HaCaT migration. In addition, unboiled exosome (0.1 ∼ 20 µ g/mL) dose-dependently stimulated sprout outgrowth in HaCats. These results demonstrate that in exosome from HaCaTs, heat-stable components such as lipid may induce HaCaT proliferation and heat-unstable components such as protein may stimulate migration and sprout outgrowth in HaCaTs, thereby leading to reepithelialization and skin-wound healing activities. It is concluded that exosomes from HaCaTs may be used as cosmetic materials.","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"34 1","pages":"359-366"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77682415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-30DOI: 10.15230/SCSK.2016.42.4.421
Gyeong Ah Sung, Mi Hye Kim, S. Park
본 연구에서는 화장품 신소재 개발을 위해 한의약적 포제법을 적용하여 흰점박이꽃무지 추출물을 제조하고 포제방법에 따른 항염 및 미백활성을 평가하였다. 모든 실험은 생(生), 1회 초법(炒法), 2회 초법(炒法), 3회 초법(炒法), 증법(蒸法)을 적용한 흰점박이꽃무지를 이용하였다. 각 포제법을 적용한 흰점박이꽃무지의 ...
{"title":"Anti-inflammatory and Whitening Effects of Protaetia brevitarsis Seulensis Extracts by Oriental Conversion Methods","authors":"Gyeong Ah Sung, Mi Hye Kim, S. Park","doi":"10.15230/SCSK.2016.42.4.421","DOIUrl":"https://doi.org/10.15230/SCSK.2016.42.4.421","url":null,"abstract":"본 연구에서는 화장품 신소재 개발을 위해 한의약적 포제법을 적용하여 흰점박이꽃무지 추출물을 제조하고 포제방법에 따른 항염 및 미백활성을 평가하였다. 모든 실험은 생(生), 1회 초법(炒法), 2회 초법(炒法), 3회 초법(炒法), 증법(蒸法)을 적용한 흰점박이꽃무지를 이용하였다. 각 포제법을 적용한 흰점박이꽃무지의 ...","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"2 1","pages":"421-432"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73148434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-30DOI: 10.15230/SCSK.2016.42.4.413
G. Nam
하이드록시 산(hydroxy acid, HA)은 피부 각질층에 대한 박리효과로 노화방지와 피부 보습을 높이는데 효과를 보여, 피부 외용제와 화장품으로서 많은 활용을 하고 있다. 그 중에서 가장 효과적으로 빠른 시간 내에 나타나는 각질 박리는 화장품 제형 pH에 의해 효과를 보이는 것으로 많은 보고가 있다. 그러나 pH에 의한 ...
{"title":"Stratum Corneum Exfoliation Effect with Hydroxy Acid according pH","authors":"G. Nam","doi":"10.15230/SCSK.2016.42.4.413","DOIUrl":"https://doi.org/10.15230/SCSK.2016.42.4.413","url":null,"abstract":"하이드록시 산(hydroxy acid, HA)은 피부 각질층에 대한 박리효과로 노화방지와 피부 보습을 높이는데 효과를 보여, 피부 외용제와 화장품으로서 많은 활용을 하고 있다. 그 중에서 가장 효과적으로 빠른 시간 내에 나타나는 각질 박리는 화장품 제형 pH에 의해 효과를 보이는 것으로 많은 보고가 있다. 그러나 pH에 의한 ...","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"54 1","pages":"413-420"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78106673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-30DOI: 10.15230/SCSK.2016.42.4.393
김윤선, 김유미, 이상화
Ultraviolet (UV) irradiation from the sun is the primary environmental factor that causes skin damages including skin cancer and premature skin aging. Because, even the most powerful sunscreen can’t always afford enough protection, it is necessary to enhance the defensive power of skin against UV. Recently, constitutive photomorphogenic protein-1 (COP1) has shown to contribute to the regulation of UVB response of keratinocytes. In this study, we represent that COP1 and its associated protein, de-etiolated 1 (DET1), might participate in photoaging process in human skin as Arabidopsis COP1 does sun-protective function in plants. After UVB irradiation, the decrease of COP1 and DET1 mRNA expression was followed by the increase of c-Jun total protein. Moreover, transfection with DNA vectors expressing COP1 and DET1 down-regulated the c-Jun total protein. We found that Zanthoxylum piperitum extract (ZE) up-regulated the expression of COP1 and DET1 on human keratinocytes, and inhibited the expression of MMP1 which is one of the genes regulated by c-Jun signal. In addition, ZE has been reported to stimulate PPAR-α and strengthen the skin barrier. We found that ZE decreased the UVB-induced IL-6 and IL-8 in NHEK cells. In human study, ZE protected skin against UV-B induced erythema and erythema-induced pigmentation. These results indicate that ZE could be useful for the protection against the adverse effects of UV irradiation through various mechanisms.
{"title":"Effect of Zanthoxylum piperitum Extract on Human Skin Protection from UVB by Regulation of COP1 and PPAR-α","authors":"김윤선, 김유미, 이상화","doi":"10.15230/SCSK.2016.42.4.393","DOIUrl":"https://doi.org/10.15230/SCSK.2016.42.4.393","url":null,"abstract":"Ultraviolet (UV) irradiation from the sun is the primary environmental factor that causes skin damages including skin cancer and premature skin aging. Because, even the most powerful sunscreen can’t always afford enough protection, it is necessary to enhance the defensive power of skin against UV. Recently, constitutive photomorphogenic protein-1 (COP1) has shown to contribute to the regulation of UVB response of keratinocytes. In this study, we represent that COP1 and its associated protein, de-etiolated 1 (DET1), might participate in photoaging process in human skin as Arabidopsis COP1 does sun-protective function in plants. After UVB irradiation, the decrease of COP1 and DET1 mRNA expression was followed by the increase of c-Jun total protein. Moreover, transfection with DNA vectors expressing COP1 and DET1 down-regulated the c-Jun total protein. We found that Zanthoxylum piperitum extract (ZE) up-regulated the expression of COP1 and DET1 on human keratinocytes, and inhibited the expression of MMP1 which is one of the genes regulated by c-Jun signal. In addition, ZE has been reported to stimulate PPAR-α and strengthen the skin barrier. We found that ZE decreased the UVB-induced IL-6 and IL-8 in NHEK cells. In human study, ZE protected skin against UV-B induced erythema and erythema-induced pigmentation. These results indicate that ZE could be useful for the protection against the adverse effects of UV irradiation through various mechanisms.","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"41 1","pages":"393-401"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90437984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-30DOI: 10.15230/SCSK.2016.42.3.227
J. Hyun, Jung Eun Kim, Hyun Sook Yeum, Jung-Min Song, Mi Ryang Kim, N. Lee
본 연구에서는 세토카 가지 정유의 주요 성분을 분석하고 이들의 항균, 항염 및 세포독성 실험을 진행하였다. 세토카는 제주도에서 널리 재배되고 있는 감귤류의 품종이다. 세토카 나무의 가지는 간벌 작업으로 인해 대부분 폐기되고 있고, 이러한 폐자원의 활용은 최근 많은 관심을 받고 있다. 정유 성분은 세토카 가지의 ...
{"title":"Chemical Composition and Biological Activities of Essential Oil from ‘Setoka’ Branches","authors":"J. Hyun, Jung Eun Kim, Hyun Sook Yeum, Jung-Min Song, Mi Ryang Kim, N. Lee","doi":"10.15230/SCSK.2016.42.3.227","DOIUrl":"https://doi.org/10.15230/SCSK.2016.42.3.227","url":null,"abstract":"본 연구에서는 세토카 가지 정유의 주요 성분을 분석하고 이들의 항균, 항염 및 세포독성 실험을 진행하였다. 세토카는 제주도에서 널리 재배되고 있는 감귤류의 품종이다. 세토카 나무의 가지는 간벌 작업으로 인해 대부분 폐기되고 있고, 이러한 폐자원의 활용은 최근 많은 관심을 받고 있다. 정유 성분은 세토카 가지의 ...","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"38 1","pages":"227-233"},"PeriodicalIF":0.0,"publicationDate":"2016-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85669659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-30DOI: 10.15230/SCSK.2016.42.3.285
In‐Hae Kim, Jae Hwa Lee
To investigate the effect of dietary fiber from mozuku, Cladosiphon novae-caledoniae kylin (C. novae-caledoniae kylin) on the skin care, we measured anti-oxidant activity, anti-microbial activities, tyrosinase activity inhibition and elastic activity. B16F10 melanoma cell (MTT assay) were used to measure cell viability. MC and MI exhibited in vitro antibacterial activity against Staphyloccus aureus (S. aureus) and MRSA without antifungal activity. Mozuku extract (MS) showed excellent tyrosinase inhibition effect compared to arbutin as a positive control (to 49% for tyrosine). The wrinkle-improving effect was relatively low. However, wrinkle-improving effect was relatively low. DPPH free radical scavenging activity was 89% in a concentrations at 500 μg/mL. These results indicate that the mozuku extracts may be an effective cosmetic ingredient for skin whitening.
{"title":"Cosmetic Effects of Dietary Fiber from Mozuku, Cladosiphon novae-caledoniae Kylin","authors":"In‐Hae Kim, Jae Hwa Lee","doi":"10.15230/SCSK.2016.42.3.285","DOIUrl":"https://doi.org/10.15230/SCSK.2016.42.3.285","url":null,"abstract":"To investigate the effect of dietary fiber from mozuku, Cladosiphon novae-caledoniae kylin (C. novae-caledoniae kylin) on the skin care, we measured anti-oxidant activity, anti-microbial activities, tyrosinase activity inhibition and elastic activity. B16F10 melanoma cell (MTT assay) were used to measure cell viability. MC and MI exhibited in vitro antibacterial activity against Staphyloccus aureus (S. aureus) and MRSA without antifungal activity. Mozuku extract (MS) showed excellent tyrosinase inhibition effect compared to arbutin as a positive control (to 49% for tyrosine). The wrinkle-improving effect was relatively low. However, wrinkle-improving effect was relatively low. DPPH free radical scavenging activity was 89% in a concentrations at 500 μg/mL. These results indicate that the mozuku extracts may be an effective cosmetic ingredient for skin whitening.","PeriodicalId":17401,"journal":{"name":"Journal of the Society of Cosmetic Scientists of Korea","volume":"34 1","pages":"285-295"},"PeriodicalIF":0.0,"publicationDate":"2016-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77505489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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