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A Review of the Analysis of Ground Reaction Force among Adults with Lower Limb Problems 成人下肢问题的地面反作用力分析综述
Pub Date : 2023-07-01 DOI: 10.17576/jskm-2023-2102-01
Deepashini Harithasan, Nur Aqilah Binti Abd Razak
The ground reaction force (GRF) is the equal opposing load transfer from the body to the ground, also called vertical load transfer. The GRF would produce stress waves transmitted toward the lower extremities during the heel strike of a gait cycle. Too much force imposed on the lower extremities for an extended period will cause harmful effects such as injuries or alterations in gait. This article presents a review of the literature on GRF analysis among adults with lower limb problems where comparisons between healthy and unhealthy subjects were analyzed, focusing on the compensation in each lower limb. A literature search of published articles in Science Direct and PubMed databases from August 2015 to March 2021 was analyzed. The keywords used for the search were (plantar force OR vertical load transfer OR ground reaction force) AND (lower limb OR lower extremities OR leg OR foot) AND (impairment OR problem OR injury). The literature search identified 22 relevant studies which were screened independently by two reviewers. Lower limb problems such as unilateral transfemoral amputation, unilateral transtibial amputation, patellofemoral pain, anterior cruciate ligament injury, knee arthroplasty, knee osteoarthritis, diabetic foot, total hip replacement, pronated foot proved to alter the GRF significantly. Patients used to shift their weight on the opposite leg as compensation, which acts as a pain-free mechanism. This paper has provided sufficient understanding regarding GRF among adults with lower limb problems. The knowledge concerning compensation may help physical therapists implement the appropriate intervention for patients with lower limb problems.
地面反作用力(GRF)是从物体到地面的相等反向载荷传递,也称为垂直载荷传递。GRF会在步态周期的脚跟撞击过程中产生向下肢传递的应力波。长时间对下肢施加过大的力会造成伤害或步态改变等有害影响。本文综述了在有下肢问题的成年人中进行GRF分析的文献,其中分析了健康和不健康受试者之间的比较,重点是每个下肢的补偿。分析了2015年8月至2021年3月在Science Direct和PubMed数据库中发表的文章的文献检索。用于搜索的关键词是(足底力或垂直负荷转移或地面反作用力)AND(下肢或下肢或腿或脚)AND(损伤或问题或损伤)。文献检索确定了22项相关研究,由两名评审员独立筛选。下肢问题,如单侧经股截肢、单侧经胫骨截肢、髌股疼痛、前交叉韧带损伤、膝关节置换术、膝关节骨性关节炎、糖尿病足、全髋关节置换术和内旋足,被证明会显著改变GRF。患者过去常常将体重转移到另一条腿上作为补偿,这是一种无痛机制。本文对有下肢问题的成年人GRF有足够的了解。有关补偿的知识可以帮助理疗师对下肢问题患者进行适当的干预。
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引用次数: 0
Methods of Delivering Oral Hygiene Instructions Among Orthodontic Patients: The Past, Current and Future 正畸患者口腔卫生指导的方法:过去、现在和未来
Pub Date : 2023-07-01 DOI: 10.17576/jskm-2023-2102-05
Deborah Anne NATHAN DHANARAJU, Noor Sam Ahmad, Nurul Asyikin Yahya, Asma Alhusna Abang Abdullah
This review paper aims to present the evolution in methods of delivering oral hygiene information to orthodontic patients. Orthodontic fixed appliance treatment confers numerous benefits to patients in terms of occlusion, function and aesthetics, but it is associated with unwanted consequences due to challenges in maintaining oral hygiene. The ways of delivering oral hygiene information to patients have progressed over the years. Recent years have seen an increase in the popularity of incorporating technology in delivering oral hygiene information and monitoring of oral hygiene practices. The use of video-based instructions to web-based platforms such as Massive Open Online Course (MOOC) and social media platforms such as YouTube, Instagram and TikTok have all become a mode of oral hygiene information conveyance. Mobile apps are now a popular means to keep track of oral care practices such as toothbrushing frequency. The active ingredients of oral care products have improved providing a greater anticariogenic and antiplaque effect to the user as have the design of toothbrushes and even dental floss. In the future, more advanced technology may be used, such as artificial intelligence (AI) and machine learning, to create intelligent machines that can help educate patients on oral health maintenance and improvement.
本文旨在介绍向正畸患者提供口腔卫生信息的方法的发展。正畸固定矫治器治疗在咬合、功能和美观方面为患者带来了许多好处,但由于在保持口腔卫生方面的挑战,它也会带来不必要的后果。多年来,向患者提供口腔卫生信息的方式取得了进步。近年来,将技术纳入口腔卫生信息传递和口腔卫生实践监测中越来越受欢迎。在大规模开放在线课程(MOOC)等网络平台和YouTube、Instagram和TikTok等社交媒体平台上使用基于视频的指导,都已成为口腔卫生信息传递的一种模式。移动应用程序现在是一种流行的跟踪口腔护理实践(如刷牙频率)的手段。口腔护理产品的活性成分已经得到改善,为使用者提供了更大的防龋和防牙菌斑效果,牙刷甚至牙线的设计也是如此。未来,可能会使用更先进的技术,如人工智能(AI)和机器学习,来创建智能机器,帮助教育患者口腔健康维护和改善。
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引用次数: 0
Psychometric Properties of The Malay Version of The Personal Wellbeing Index: A Preliminary Study Among Caregivers of Children with Autism Spectrum Disorder 马来版个人幸福指数的心理测量特性:对自闭症谱系障碍儿童照顾者的初步研究
Pub Date : 2023-07-01 DOI: 10.17576/jskm-2023-2102-12
Shobnaa Tinagaran, Hanif Farhan Mohd Rasdi, D. Harun, Kamaruddin Hassan, Shahirah Md Rasid
Caregivers of children with Autism Spectrum Disorder (ASD) can have a compromised quality of life due to caregiving burden and parenting stress. The Personal Wellbeing Index (PWI) is one of the instruments that measure the subjective wellbeing dimension. This study intended to explore this instrument’s construct validity and reliability and compare the subjective wellbeing among caregivers based on sociodemographic characteristics. A cross-sectional study was conducted on 53 caregivers of children with ASD recruited from occupational therapy clinics at Hospital Canselor Tuanku Muhriz (HCTM) and the Faculty of Health Sciences, UKM. The PWI has one global life satisfaction construct (1 item) and subjective wellbeing (8 items). The rating scale is anchored from 0 (no satisfaction at all) to 10 (completely satisfied). The statistical analysis indicated that the Malay version of PWI has acceptable unidimensionality (outer loadings >0.5 for all items), convergence validity (Average Variance Extracted (AVE)=0.5781), constructs validity (r=0.812, p<0.001), and construct reliability (.A=0.8864, .c=0.9046, a=0.8761). Marital status is significant in achieving life and personal relationships while health issues are significant only in personal health. The Malay version has good construct validity and reliability and can measure the subjective wellbeing of the caregivers of children with autism in Malaysia. The psychometric properties of the PWI Malay version can be further established with a larger sample size. In the future, a national norm of Malaysians’ wellbeing could be developed to interpret their wellbeing level.
自闭症谱系障碍(ASD)儿童的照顾者可能会因为照顾负担和养育压力而生活质量受损。个人幸福指数(PWI)是衡量主观幸福维度的工具之一。本研究旨在探讨该工具的结构有效性和可靠性,并根据社会人口学特征比较照顾者的主观幸福感。一项横断面研究对从Canselor Tuanku Muhriz医院(HCTM)和英国医学院健康科学学院的职业治疗诊所招募的53名ASD儿童护理人员进行了研究。PWI有一个全局生活满意度结构(1个项目)和主观幸福感(8个项目)。评分范围从0(完全不满意)到10(完全满意)。统计分析表明,马来语版PWI具有可接受的单维度(所有项目的外部负荷均>0.5)、收敛有效性(提取的平均方差(AVE)=0.5781)、构念有效性(r=0.812,p<0.001),和结构可靠性(.A=0.864,.c=0.9046,A=0.8761)。婚姻状况对实现生活和人际关系具有重要意义,而健康问题仅对个人健康具有重要意义。马来语版本具有良好的结构有效性和可靠性,可以衡量马来西亚自闭症儿童照顾者的主观幸福感。PWI马来语版本的心理测量特性可以通过更大的样本量来进一步确定。未来,可以制定一个马来西亚人幸福感的国家规范来解释他们的幸福感水平。
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引用次数: 0
Malay-Translated Version and Content Validation of Parent Goals for Shared Reading Questionnaire 马来语翻译版与家长共享阅读目标问卷的内容验证
Pub Date : 2023-07-01 DOI: 10.17576/jskm-2023-2102-03
Sen SHUI PING, Mohd Normani Zakaria, Affizal Ahmad
The interaction between adults and children during shared reading contributes to the conversation and reading in hand and makes the activity interactive. It is, therefore, imperative to understand parents’ goals for shared reading with their children as it will influence their behaviour and, in turn, affect their children’s development of language and literacy skills. In Malaysia, no local psychometric instrument identifying parent goals for shared reading is available. This study aims to translate the English version of the Parent Goals for Shared Reading Questionnaire (PGSRQ) into Malay and validate the translated questionnaire. Four qualified translators carried out the translation processes, and a panel of eight experts subsequently validated the Malay-translated version of PGSRQ. Of 33 items, the validation assessment revealed that 17 items had a content validity ratio (CVR) value of 1.0, while 12 items had a CVR value of 0.8. Only four items had a CVR value lower than 0.78 and were retranslated and modified. The findings of this study can pave the way for more research efforts in the field of shared reading in Malaysia. The questionnaire can also assist a speech therapist in assessing the goals that parents have on shared reading to come up with better designs for shared book reading intervention.
在共享阅读过程中,成人和儿童之间的互动有助于对话和阅读,使活动具有互动性。因此,了解父母与孩子共同阅读的目标是必要的,因为这将影响他们的行为,进而影响孩子的语言和读写技能的发展。在马来西亚,没有当地的心理测量工具可以确定父母共同阅读的目标。本研究旨在将英文版的“家长共同阅读目标问卷”(PGSRQ)翻译成马来文,并验证翻译后的问卷。四名合格的翻译人员进行了翻译过程,由八名专家组成的小组随后验证了PGSRQ的马来语翻译版本。33个项目中,17个项目的内容效度比(CVR)值为1.0,12个项目的CVR值为0.8。只有4个条目的CVR值低于0.78,需要重新翻译和修改。本研究的发现可以为马来西亚共享阅读领域的更多研究工作铺平道路。问卷还可以帮助语言治疗师评估家长对共享阅读的目标,从而提出更好的共享阅读干预设计。
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引用次数: 0
A Preliminary Content Validity Study of the Malay Version of READI-SF (Kajian Awal Kesahan Kandungan Versi Bahasa Melayu bagi READI-SF) 马来文版READI-SF内容有效性的初步研究
Pub Date : 2023-07-01 DOI: 10.17576/jskm-2023-2102-02
Affizal Ahmad, Nik Nor Sumazeani NIK MIN, Mohd Normani Zakaria
Readiness for treatment reflects the individual’s motivation to seek help and preparedness to engage in treatment activities. The READI-SF aimed to assess parental readiness to engage in treatment. The present study aimed to translate the English version of READI-SF into the Malay language and subsequently assess its content validity using the content validity ratio (CVR), content validity index (CVI) and modified kappa analyses. Four independent translators carried out the translation procedures. Eight clinical professionals were involved as content experts. Of 17 items, six items needed to be revised due to low CVR values (< 0.75). Based on unfavourable individual CVI (I-CVI) results (< 0.78), two items (for item relevancy) and six items (for item clarity) had to be modified. The overall CVI of the questionnaire (S-CVI) was found to be good (i.e., 0.91 for item relevancy and 0.83 for item clarity). Nine items needed to be revised, and the modifications were carried out accordingly. At the end of the study, a valid Malay-translated READI-SF was produced. It has good potential to serve as a clinical tool to assess the readiness of Malay-speaking parents to engage in treatment. However, prior to its intended clinical application, further research is warranted to assess other aspects of validity (e.g., face validity, construct validity, and criterion-related validity), as well as READI-SF reliability.
治疗准备反映了个人寻求帮助的动机和参与治疗活动的准备。read - sf旨在评估父母参与治疗的准备情况。本研究旨在将英文版的read - sf翻译成马来语,然后使用内容效度比(CVR)、内容效度指数(CVI)和修正kappa分析来评估其内容效度。四名独立的翻译人员进行了翻译程序。8名临床专业人员作为内容专家参与。在17个项目中,有6个项目由于CVR值较低(< 0.75)而需要修改。基于不利的个体CVI (I-CVI)结果(< 0.78),必须修改两个项目(项目相关性)和六个项目(项目清晰度)。调查问卷的整体CVI (S-CVI)较好(即,项目相关性为0.91,项目清晰度为0.83)。需要修改的项目有9个,相应进行了修改。在研究结束时,产生了一个有效的马来语翻译的read - sf。它很有可能作为一种临床工具来评估讲马来语的父母是否愿意接受治疗。然而,在其预期的临床应用之前,需要进一步的研究来评估其他方面的效度(例如,面孔效度、结构效度和标准相关效度),以及read - sf的信度。
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引用次数: 0
Knowledge and Perception of Fluoride in Drinking Water among Residents of Precinct 9, Putrajaya, Malaysia 马来西亚普特拉贾亚9区居民对饮用水中氟化物的认知
Pub Date : 2023-07-01 DOI: 10.17576/jskm-2023-2102-14
Fatin Nor Athirah Yahaya, Shaharuddin MOHD SHAM, Vera Yulyani
The knowledge and beliefs on the presence of fluoride in drinking water, its purpose and the associated health risks aids in equate water fluoridation and effective prevention programs. Water fluoridation is a safe, effective, and necessary method where adequate doses of fluoride is added into drinking water supplies with the target of assisting in tooth restoration and preventing tooth decay and dental caries. Therefore, this study identifies the level of knowledge and perception of fluoride in drinking water among residents living in Precinct 9, Putrajaya Methods: A cross-sectional, self-administered online questionnaire was used to examine knowledge and perception of fluoride in drinking water of 240 Precinct 9 residents. Descriptive analysis was applied for socio-demographic data and Chi-square was used to compare discrete data. All data obtained were further analyzed using SPSS Version 23.0. Results: The highest frequency (percentage) of residents were 213 (88.8%), aged 18-64 years old, 141 (58.8%) female, 214 (89.2%) with tertiary education background and 125 (51.1%) of them lived in Precinct 9 for more than 10 years. Of all participants, 137 (57.1%) and 83 (34.6%) have poor knowledge and medium perception regarding fluoride in drinking water respectively. There was a significant association between those with higher education level with knowledge (p=0.02) and perception (p=0.005) where they were more likely to know about overall fluoride in drinking water. Conclusion: Most participants had limited knowledge and negative perception of fluoride beyond a general sense it was beneficial. It appears that in moving forward to receive the water fluoridation support will need to attend to the challenge of anti-fluoride sentiment influence
关于饮用水中氟化物的存在、其用途和相关健康风险的知识和信念有助于等同于水氟化和有效的预防计划。水氟化是一种安全、有效和必要的方法,在饮用水中添加足够剂量的氟化物,目的是帮助牙齿修复和预防蛀牙和龋齿。因此,本研究确定了居住在Putrajaya 9区居民对饮用水中氟化物的知识和感知水平。方法:采用横断面、自填在线问卷调查240名9区居民的饮用水中氟化物知识和感知。描述性分析用于社会人口统计数据,卡方用于比较离散数据。使用SPSS 23.0版对获得的所有数据进行进一步分析。结果:居民频率(百分比)最高的是213人(88.8%),年龄在18-64岁之间,141人(58.8%)为女性,214人(89.2%)具有高等教育背景,其中125人(51.1%)在9区居住超过10年。在所有参与者中,137人(57.1%)和83人(34.6%)分别对饮用水中的氟缺乏知识和中等感知。教育水平较高的人在知识(p=0.02)和感知(p=0.005)方面存在显著关联,他们更有可能了解饮用水中的总体氟化物。结论:大多数参与者对氟的认识有限,对氟的负面看法超出了一般意义——这是有益的。看来,在接受水氟化支持的过程中,需要应对反氟情绪影响的挑战
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引用次数: 0
Current Diagnostic Techniques and the Use of Rapid Point-of-Care (POC) Testing to Diagnose Familial Hypercholesterolemia (FH) 目前的诊断技术和快速护理点(POC)检测在诊断家族性高胆固醇血症(FH)中的应用
Pub Date : 2023-07-01 DOI: 10.17576/jskm-2023-2102-04
Lina Khalida Saidi, Zam Zureena MD RANI, Siti Aishah Silaiman, Ismail Aziah, Anis Amirah Alim, Sharipah Nadzirah SYED AHMAD AYOB, Dee CHANG FU, A. A. Hamzah, Nor Azian ABDUL MURAD
Familial hypercholesterolemia (FH) is an autosomal dominant inherited genetic disease characterized by increased concentrations of low-density lipoprotein (LDL-C) cholesterol in the blood. The risk of premature coronary heart disease in FH patients may increase without early treatment. Advancement in molecular biology techniques has enable early detection and diagnosis of FH. These techniques are cost-effective and have a shorter turnaround time. The current diagnostic tools available for FH diagnosis involving algorithm-based scoring criteria and various molecular diagnosis methods including next-generation sequencing (NGS), Sanger sequencing, Multiplex ligation-dependent probe amplification (MLPA) and DNA hybridisation assay are discussed in this review. However, molecular genetic testing is not widely available due to time-consuming procedures, high cost and requires trained personnel. Thus, this 36 review highlights the use of point of care (POC) testing as an approach to diagnose FH, particularly in countries lacking infrastructure and expertise in this field. Lateral flow testing (LFA) has gained attention as a POC diagnostic tool due to its simplicity, low cost and involved simple procedure and settings. The advantages of LFA made this technique a potential tool in addressing challenges in diagnosing FH, particularly for early diagnosis of family members.
家族性高胆固醇血症(FH)是一种常染色体显性遗传性疾病,其特征是血液中低密度脂蛋白(LDL-C)胆固醇浓度升高。FH患者如果不早期治疗,患早发冠心病的风险可能会增加。分子生物学技术的进步使得FH的早期检测和诊断成为可能。这些技术具有成本效益,并且周转时间更短。本文讨论了目前可用于FH诊断的诊断工具,包括基于算法的评分标准和各种分子诊断方法,包括下一代测序(NGS)、Sanger测序、多重连接依赖性探针扩增(MLPA)和DNA杂交分析。然而,由于耗时的程序、高昂的成本以及需要训练有素的人员,分子基因检测并没有广泛可用。因此,这36篇综述强调了使用护理点(POC)检测作为诊断FH的一种方法,特别是在缺乏该领域基础设施和专业知识的国家。侧流检测(LFA)作为一种POC诊断工具,由于其简单、成本低、程序和设置简单而受到关注。LFA的优势使该技术成为解决FH诊断挑战的潜在工具,特别是对家庭成员的早期诊断。
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引用次数: 0
Parent-Implemented Language Intervention for Late Talkers: A Scoping Review 晚语者父母实施的语言干预:范围回顾
Pub Date : 2023-01-01 DOI: 10.17576/jskm-2023-2101-04
N. H. Tukiran, Nor Azrita Mohamed Zain, Natrah Ahmad Nordin, Nadzirah Ahmad Basri
Parent-implemented language intervention (PILI) is one of the intervention approaches used in managing late talkers (LTs). Yet, there are few evidence-based PILI programs available for parents of LTs. This scoping review aimed to (a) assess the characteristics of participants depicted in the literature related to PILI programs for parents of LTs, (b) provide an overview of the structure and design of the available PILI programs for parents of LTs, and (c) explore the effectiveness of the programs in relation to the characteristics of reviewed studies. The scoping review was performed by adhering to the general principles prescribed by Arksey and O’Malley (2005). Articles that fulfilled the inclusion criteria and were published from 1980 to 2018 were selected. Two reviewers independently charted the information from the identified articles. A total of 15 articles were selected. The results were reviewed in terms of participant characteristics, intervention characteristics, and effectiveness of PILI programs. Most adult participants in PILI studies were mothers and included child participants with either expressive language delay or receptive and expressive language delay. Moreover, there were different structures and designs of PILI programs for parents of LTs. Preliminary evidence indicated that PILI was more effective than no/delayed intervention and could be as effective as direct therapy provided by clinicians. A discussion related to the findings was also presented. Keywords:parent-implemented language intervention, late talkers, parent training, language intervention
父母实施的语言干预(PILI)是一种用于管理晚说话者的干预方法。然而,很少有基于证据的PILI项目可供ltt的父母使用。本综述旨在(a)评估与低龄儿童家长的PILI项目相关的文献中描述的参与者的特征,(b)概述针对低龄儿童家长的PILI项目的结构和设计,以及(c)探讨与所回顾研究的特征相关的项目的有效性。范围审查是按照Arksey和O 'Malley(2005)规定的一般原则进行的。入选时间为1980年至2018年,符合入选标准的文章。两名审稿人独立地从已确定的文章中绘制信息图表。共有15篇文章入选。从参与者特征、干预特征和PILI项目的有效性方面对研究结果进行了回顾。在PILI研究中,大多数成年参与者是母亲,包括有表达性语言迟缓或接受性和表达性语言迟缓的儿童参与者。此外,针对低年级学生家长的PILI项目也存在不同的结构和设计。初步证据表明,PILI比不干预/延迟干预更有效,与临床医生提供的直接治疗一样有效。还就调查结果进行了讨论。关键词:父母实施语言干预;晚说话者;父母训练
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引用次数: 0
Retrospective Study of The Outcome of Primary Repair of Arteriovenous Fistula (AVF) Aneurysm and Pseudoaneurysm in Secondary Hospital Setting 二级医院动静脉瘘(AVF)动脉瘤和假性动脉瘤一期修复效果的回顾性研究
Pub Date : 2023-01-01 DOI: 10.17576/jskm-2023-2101-02
Ong Xin Zen, Ling Li Fan, Philip Ding Hsin Loong, Chong Kar Hon, Goh Neng Xiang, Kang Jo An, U. Ramasamy
Aneurysms and pseudoaneurysm are commonly encountered with arteriovenous vascular access for haemodialysis. They are difficult complications to manage. Due to the limited number of vascular centers available, patients were unable to seek treatment until further complications arise. The technique of partial aneurysmectomy and primary repair was adopted as the method of repair in this study. A total of 20 cases underwent the surgery from 2019 to 2020. Among the 20 cases, one patient had two pseudoaneurysms at different location which requires her to undergo the procedure twice. The successful cannulation rate post repair was 70% whereas the overall complication rate was 35% which might be attributed to the small sample size. Overall, this study demonstrated that AVF aneurysm and pseudoaneurysm can be safely treated with this approach and can be done effectively in non-vascular centers by general surgeons. Keywords: pseudoaneurysm, aneurysm repair, arteriovenous fistula
动脉瘤和假性动脉瘤常见于动静脉血管通路进行血液透析。它们是难以处理的复杂问题。由于可用的血管中心数量有限,患者无法寻求治疗,直到出现进一步的并发症。本研究采用部分动脉瘤切除和一期修复技术作为修复方法。从2019年到2020年,共有20例患者接受了手术。在20例病例中,一名患者在不同位置有两个假性动脉瘤,这需要她接受两次手术。修复后成功插管率为70%,而总并发症率为35%,这可能归因于样本量小。总的来说,这项研究表明,这种方法可以安全地治疗AVF动脉瘤和假性动脉瘤,并且普通外科医生可以在非血管中心有效地进行治疗。关键词:假性动脉瘤,动脉瘤修复,动静脉瘘
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引用次数: 0
Emergence Of Dengue Virus Type 4 During COVID-19 Pandemic In Patients Admitted to a Teaching Hospital In Malaysia 马来西亚一家教学医院收治的患者在COVID-19大流行期间出现4型登革热病毒
Pub Date : 2023-01-01 DOI: 10.17576/jskm-2023-2101-11
Mahrunissa Mahadi, Nor Azila Muhammad Azami, N. Abdullah, S. Othman, N. Kori, H. Neoh, S. A. Salleh, Z. Zainol Rashid, P. Periyasamy
Prior to COVID-19, dengue was an important public health problem in Malaysia. Due to the movement control order imposed by the Malaysian government to curb the COVID-19 transmission, a study predicted that mosquito-borne diseases would increase during lockdown and partial lockdown seasons. Thus, this study aims to determine the current situation of dengue incidence during the pre-COVID-19 pandemic (2019) and during the COVID-19 pandemic (2020 and 2021). We compared the number of laboratory-confirmed cases in the pre-COVID19 year (2019) and during the COVID-19 pandemic (2020 and 2021). In addition to that, we characterized the clinical manifestation, dengue serotype and viremia levels of dengue patients that were admitted to the Hospital Cancelor Tuanku Muhriz. We found a significant decrease in the number of laboratory-confirmed cases between COVID-19 pandemic and the pre-covid period (p2020=0.064; p2021<0.001). In this study, we found DENV 4 serotype was the most common serotype in dengue patients admitted to our hospital. There was no significant correlation between DENV serotype/viremia level with clinical manifestation of dengue fever and dengue with warning signs. However, patients infected with DENV4 had the highest viral load compared to patients infected with other serotypes. We also found high viremia levels were significantly associated with the febrile phase. Keywords dengue; clinical manifestation; dengue in Malaysia
在新冠肺炎之前,登革热是马来西亚的一个重要公共卫生问题。由于马来西亚政府为遏制新冠肺炎传播而实施的行动控制令,一项研究预测,在封锁和部分封锁季节,蚊子传播的疾病将增加。因此,本研究旨在确定新冠肺炎大流行前(2019年)和新冠肺炎大流行期间(2020年和2021年)登革热发病率的现状。我们比较了COVID19年前(2019年)和新冠肺炎大流行期间(2020年和2021年)实验室确诊病例的数量。除此之外,我们还对Cancelor Tuanku Muhriz医院收治的登革热患者的临床表现、登革热血清型和病毒血症水平进行了表征。我们发现,从新冠肺炎大流行到新冠疫情前,实验室确诊病例数量显著下降(p2020=0.064;p2021<0.001)。在这项研究中,我们发现DENV 4血清型是入院登革热患者中最常见的血清型。登革病毒血清型/病毒血症水平与登革热和有警告信号的登革热的临床表现之间没有显著相关性。然而,与感染其他血清型的患者相比,感染DENV4的患者的病毒载量最高。我们还发现高病毒血症水平与发热期显著相关。登革热;临床表现;马来西亚登革热
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引用次数: 0
期刊
Jurnal Sains Kesihatan Malaysia
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