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TESTING AND CHARACTERIZATION OF SLUDGE FROM WASTEWATER TREATMENT 废水处理中污泥的测试和表征
Pub Date : 2022-09-30 DOI: 10.35120/kij5403381m
Matija Milošević, A. Milošević, S. Nedeljković, B. Nešić, Novak Ranđelović
The paper presents the procedure of examination and characterization of sludge from wastewatertreatment. This procedure includes: sampling, identification with categorization of waste, characterization dependingon the degree of danger, characterization of the subject waste as hazardous waste and determination of theconcentration of hazardous substances, determination of physico-chemical and toxicological characteristics andeffects on human health, determination of the impact on the environment and others procedures in accordance withthe applied methodology and preparation of reports on waste testing. The testing and characterization process beginswith sampling and ends with reporting. The goal of wastewater treatment is to obtain clean water, while sludge isproduced as a by-product. Clean water returns to nature, and sludge goes to treatment and final disposal. Thetreatment can be: sanitary disposal, recycling using composting technology with the aim of obtaining compost orenergy utilization as solid fuel or using anaerobic digestion with the aim of obtaining biogas.
本文介绍了污水处理产生的污泥的检测和表征方法。该程序包括:抽样、识别和废物分类、根据危险程度进行表征、将主题废物定性为危险废物并确定危险物质的浓度、确定物理化学和毒理学特征以及对人体健康的影响、确定对环境的影响和根据应用方法编制废物测试报告的其他程序。测试和表征过程以抽样开始,以报告结束。废水处理的目的是获得清洁的水,而污泥作为副产品产生。清洁的水回归自然,污泥进行处理和最终处置。处理可以是:卫生处置,利用堆肥技术回收,目的是获得堆肥或作为固体燃料利用,或利用厌氧消化,目的是获得沼气。
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引用次数: 0
RELIABILITY OF STATEMENTS AND EXPERIENCES OF CELIAC PATIENTS ON GLUTEN-FREE PRODUCTS/QUANTITATIVE STUDY 乳糜泻患者对无谷蛋白产品的陈述和经验的可靠性/定量研究
Pub Date : 2022-09-30 DOI: 10.35120/kij5404689t
T. Tomić, Ivona Ljevak
Celiac disease is a chronic gastroenterological disease, and a lifelong gluten-free diet is a needed andnecessary therapy, which implies the exclusion of products containing gluten from the diet. The declaration ofgluten-free products is often unclear and ambiguous. The purpose of this paper was to examine celiac diseasepatients' attitudes and experiences with gluten-free diet declarations. 95 respondents from the area of HNŽ with adiagnosis of celiac disease were included in this quantitative research. The anonymous survey was conducted usingthe Google Forms tool. An anonymous survey examined sociodemographic data (age, gender, education, duration ofillness), experiences and attitudes with declarations about gluten-free diet. In this research, more than half of therespondents are extremely careful about what they consume, without exception. Participants who have beendiagnosed with celiac disease for a longer period of time completely disagree to a greater extent that they do notknow what products they can consume. Individuals with gluten sensitivity may rely more on the 'gluten-free' claimfor information about the gluten content of a product. Individuals with celiac disease, on the other hand, may bemore experienced readers of food labels and may rely more on the ingredient list. Consumer expectations havedriven the food industry to continuously adapt and improve the formulations and processing techniques used in theproduction of gluten-free products.
乳糜泻是一种慢性胃肠疾病,终生无谷蛋白饮食是一种必要的治疗方法,这意味着从饮食中排除含谷蛋白的产品。无谷蛋白产品的声明通常是不明确和模棱两可的。本研究的目的是研究乳糜泻患者对无麸质饮食宣言的态度和经历。来自HNŽ地区的95名诊断为乳糜泻的受访者被纳入了这项定量研究。这项匿名调查是使用谷歌表单工具进行的。一项匿名调查调查了社会人口统计数据(年龄、性别、教育程度、患病时间)、经历和对无麸质饮食的态度。在这项研究中,超过一半的受访者对他们消费的东西非常小心,无一例外。被诊断患有乳糜泻的参与者在更大程度上完全不同意他们不知道他们可以吃什么产品。对麸质敏感的人可能更依赖于“无麸质”的声明来获取产品中麸质含量的信息。另一方面,乳糜泻患者可能更有经验阅读食品标签,可能更依赖成分表。消费者的期望推动了食品行业不断适应和改进生产无麸质产品的配方和加工技术。
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引用次数: 0
COMPUTED TOMOGRAPHY IMAGING PRESENTATION IN THORACIC HYDATID CYSTS 胸部包虫病的计算机断层成像表现
Pub Date : 2022-09-30 DOI: 10.35120/kij5404611n
S. Nikolova
Hydatid cysts are widespread zoonosis that originate from the larval embodiment of the Echinococcusand can be frequently found in the lung and liver parenchyma, in addition, they emerge in various atypical locationsin the thoracic cavity such as the mediastinum, its vascular compounds and the heart, the interlobar fissures, thepleural and pericardial space, as well as the structures of the chest wall and the diaphragm. Computed tomographyas one of the most utilized instruments of radiology imaging has a crucial role in the diagnosis of hydatid cysts,depiction of their exact size and location, as well as estimation of impending complications.The aim of this pictorial review is to offer full scale understanding of the recurrent imaging findings in thoracichydatid disease as well as to display some rare, extra parenchymal involvement and a summary of the complicationsand differential diagnosis.We did an in depth analysis of 55 chest CT scans of patients with thoracic hydatid cysts from North Macedonia andall patients underwent a contrast enhanced chest CT according to appropriate diagnostic protocol on a 16- sliceSomatom GO computed tomograph (Siemens Healthineers, USA).Hydatid cysts in all 55 patients were divided by location and appearance in two by two categories, uncomplicatedparenchymal and extra parenchymal, and complicated or ruptured parenchymal and extra parenchymal cysts.Uncomplicated parenchymal hydatid cysts were presented by well circumscribed, low attenuating, homogenouslesions with smooth walls of varying thickness, whereas complicated or ruptured hydatid cysts could be categorizedin two forms, contained or complete rupture. The most frequent imaging findings were the air crescent sign,waterlily sign and dry cyst sign. Uncommon extra parenchymal hydatid cysts’ locations were the mediastinum,pericardium and the diaphragm.Computed tomography plays an important diagnostic role in common thoracic hydatid cysts and aids in theevaluation of rare and complicated cases.
包虫病是一种广泛存在的人畜共患病,起源于棘球蚴的幼虫,常见于肺和肝实质,此外,它们还出现在胸腔的各种非典型部位,如纵隔、其血管化合物和心脏、叶间裂隙、胸膜和心包间隙,以及胸壁和隔膜的结构。计算机断层扫描是最常用的放射成像工具之一,在包虫病的诊断、准确描述其大小和位置以及估计即将发生的并发症方面起着至关重要的作用。这篇图片回顾的目的是全面了解胸囊虫病复发的影像学表现,并展示一些罕见的、实质外的受累,总结其并发症和鉴别诊断。我们对来自北马其顿的55例胸部包虫囊肿患者的胸部CT扫描进行了深入分析,所有患者都根据适当的诊断方案在16层esomatom GO计算机断层扫描(Siemens Healthineers, USA)上进行了增强胸部CT检查。55例患者的包囊按位置和外观分为单纯实质囊肿和实质外囊肿,以及复杂或破裂的实质囊肿和实质外囊肿两类。不复杂的实质包膜囊肿表现为边界清楚、低衰减、均匀的病变,壁光滑,厚度不等,而复杂或破裂的包膜囊肿可分为两种形式,包含或完全破裂。最常见的影像学表现为气月牙征、睡莲征和干囊肿征。少见的实质外包虫病见于纵隔、心包和横膈膜。计算机断层扫描对常见的胸包虫病具有重要的诊断作用,并有助于罕见和复杂病例的评估。
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引用次数: 0
ESTHETICS IN ORTHODONTICS 正畸学中的美学
Pub Date : 2022-09-30 DOI: 10.35120/kij5404631t
Natasha Tosheska-Spasova, N. Stavreva, B. Džipunova
Pleasant appearance often means the difference between success and failure in both our personal andprofessional lives. An attractive or pleasant smile clearly enhances the acceptance of the individual in society andthe character of the smile greatly influences the attractiveness and personality of the individual. Aesthetic andattractive smile is one of the most important components that affects the overall facial aesthetics. The paperprovides important information and a systematic overview of beauty, esthetics, esthetics dentistry and cosmeticdentistry. Physical attributes of the elements of the dento-facial composition are presented in this study. The articlefocuses on three components of esthetics: macro, mini and microesthetics, classification and style of the smile.Extraoral and intraoral features of a smile are presented. Dento-facial analysis, dento-labial analysis, dento-gingivalanalysis,and dental analysis are analyzed are presented and described in detail.
在我们的个人生活和职业生涯中,良好的外表往往意味着成功与失败的区别。一个迷人的或令人愉快的微笑明显地提高了社会对个人的接受度,而微笑的性质极大地影响了个人的吸引力和个性。美学和迷人的微笑是影响整个面部美学的最重要的组成部分之一。本文提供了重要的信息,并对美容、美学、美容牙科和美容牙科进行了系统的概述。在本研究中提出了牙齿-面部组成元素的物理属性。本文重点讨论了宏观、微观和微观美学,微笑的分类和风格。介绍了微笑的口外和口内特征。对牙面分析、牙唇分析、牙牙龈分析和牙齿分析进行了详细的介绍和描述。
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引用次数: 0
THE INFLUENCE OF DYSLEXIA ON CHILDRENS' SELF-ESTEEM IN PRIMARY SCHOOL 阅读障碍对小学儿童自尊的影响
Pub Date : 2022-09-30 DOI: 10.35120/kij5405757z
Vaska Zdravkova
Dyslexia is a learning disorder that is characterized by children's impaired ability to read and spell words.Self-esteem is confidence and belief in one's own worth. Strong self-esteem is associated with good psychologicalhealth. Children spend most of their days in school and this environment forms the sense of worth for manychildren. Dyslexia regularly causes failure in school and is usually accompanied by behavioral and emotionalproblems: instability, lack of discipline, resistance, passive or aggressive attitude, refusal of school, isolation, andfeelings of inferiority (Shaywitz S.E., Shaywitz J.E., Shaywitz B.A. (2021). The most common mistakes, such asblaming the child for poor school performance or attributing the cause to psychological problems, regularly lead topoor self-image, affect their confidence, or low self-esteem (Chica, 2017). School can quickly shatter the self-esteemof a dyslexic child. Dyslexia has a negative effect on self-esteem, but this effect depends on levels of support athome and at school. Clinical research shows the emotional and motivational factors associated with dyslexia.The purpose of the present study is to investigate the factors that influence the self-esteem of students with dyslexia.Provides a brief overview of some of the key literature in this area and then describes a study conducted in threemainstream primary schools in the eastern part of the Republic of North Macedonia.Methodology: data were collected using semi-structured interviews with students who received an official diagnosisof dyslexia. Eleven students voluntarily participated in an interview. The study looked at the influence of factorssuch as comparisons with other students and the influence of teachers, peers and family on students' self-esteem.The results of the study show that these factors contribute significantly to the self-esteem of students with dyslexia.The most significant contributor to students' self-esteem is being diagnosed with dyslexia and being labeled.Conclusions: Dyslexic children with high self-esteem display more confidence and will volunteer answers or try outnew subjects/tasks than lower self-esteem children. These high self-esteem children expect to succeed and attributesuccess to their skill/ability.Recommendations: early diagnosis of dyslexia is essential to creating a positive self-image and recommends thatfurther research is needed on the meaning of the diagnosis for these learners. Children with dyslexia can achievehigher self-esteem, not just developed communication and writing competence.
阅读障碍是一种学习障碍,其特征是儿童阅读和拼写单词的能力受损。自尊是对自己价值的信心和信念。强烈的自尊与良好的心理健康有关。孩子们大部分时间都在学校度过,这种环境形成了许多孩子的价值感。阅读障碍经常导致学业失败,通常伴有行为和情绪问题:不稳定、缺乏纪律、抵抗、被动或攻击态度、拒绝上学、孤立和自卑感(Shaywitz s.e., Shaywitz j.e., Shaywitz ba .(2021))。最常见的错误,例如将孩子的学习成绩差归咎于心理问题,经常导致自我形象不佳,影响他们的信心,或低自尊(Chica, 2017)。学校可以迅速粉碎一个有阅读障碍的孩子的自尊。阅读障碍对自尊有负面影响,但这种影响取决于家庭和学校的支持水平。临床研究表明,情绪和动机因素与阅读障碍有关。本研究旨在探讨影响阅读障碍学生自尊的因素。简要概述了这一领域的一些重要文献,然后描述了在北马其顿共和国东部三所主流小学进行的一项研究。研究方法:数据收集采用半结构化访谈的学生接受官方诊断为阅读障碍。11名学生自愿参加了面试。该研究考察了与其他学生的比较以及老师、同龄人和家庭对学生自尊的影响等因素的影响。研究结果表明,这些因素对有阅读障碍的学生的自尊有显著的影响。对学生自尊最重要的贡献是被诊断患有阅读障碍并被贴上标签。结论:高自尊的失读症儿童比低自尊的儿童表现出更多的自信,并愿意自愿回答或尝试新的科目/任务。这些高自尊的孩子期望成功,并把成功归因于他们的技能/能力。建议:阅读障碍的早期诊断对于建立积极的自我形象至关重要,并建议需要进一步研究诊断对这些学习者的意义。患有阅读障碍的儿童可以获得更高的自尊,而不仅仅是发展沟通和写作能力。
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引用次数: 0
TO THE HISTORY OF THE EPITE IN BULGARIAN LITERATURE 保加利亚文学中史诗的历史
Pub Date : 2022-09-30 DOI: 10.35120/kij5405769b
A. Baeva
The subject of the article is the study of the epithet in part of the Bulgarian poetry. The purpose of thework is to determine the predominant types of epithets from the Renaissance to the Symbolists. In accordance with abasic division of epithets as traditional and deviant, an attempt has been made to see the predominant types ofepithets. It turns out that objective, non-individualizing epithets predominate next to symbolists. The work issaturated with sufficient source material.
本文的主题是对保加利亚诗歌中部分词的研究。这项工作的目的是确定从文艺复兴到象征主义的主要类型的绰号。根据传统和越轨的称谓的基本划分,试图看到主要类型的称谓。事实证明,客观的,非个体化的形容词占主导地位,仅次于象征主义。这本书有充足的原始材料。
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引用次数: 0
ANALYSIS OF THE TYPE OF ERROR IN THE STRUCTURE OF RUBBER SAMPLES 橡胶样品结构误差的类型分析
Pub Date : 2022-09-30 DOI: 10.35120/kij5403471d
Petar S. Đekić, M. Nikolic, G. Jovic
Products made of polymer materials are obtained by turning the raw material from which it is madeunder the influence of temperature and, in some cases, high pressure, into a liquid state and filling the mold cavity.This transition is often problematic because very quickly when transitioning to the liquid state, irreversible chemicalprocesses begin to occur in the material, and it is necessary that the process of reverse crystallization takes a veryshort time. This problem is very pronounced with products made of rubber. When making the raw mixture, aprocedure must be followed regarding the speed of mixing, the order of adding the components and the duration ofthe process itself. In the case of poorly chosen mixing parameters, agglomerations may occur in the structure of theproduct, which can later negatively affect the exploitation of the product itself. When the raw rubber begins totransition into the liquid phase and fills the mold cavity, the layers that are in contact with the tool form the finalstructure and shape. In case the chemical system is not balanced, i.e., speed of spilling, it may happen that the rubberdoes not fill the mold cavity and a scrap is obtained. Another problem is that if the closing speed of the tool is high,an airy structure of the material or some kind of defect in the structure may appear. Regarding this phenomenon, itmust be taken into account that the speed of spilling is always higher than the speed of closing the tool. In the caseof poor selection of vulcanization temperature and vulcanizer, certain chemical compounds may also appear thatnegatively affect the properties of the product. Also, special attention must be paid to the working environment, as itvery often happens that external bodies are found in the structure of the product, which are related to mixing andpressing procedures. The release of the material structure belongs to a special group of tests and is alwaysaccompanied by the destruction of the product. According to the type of examination, it belongs to visual control,and according to the degree of optical magnification, to macro and micro examinations. Eye inspection belongs tomacroscopic tests and is used to check the exterior of the product and this type of test is convenient because it is fastand reliable. Microscopic examinations of rubber are very complex and it is complicated because rubber is not atransparent material. Therefore, the examination of the structure is carried out on SEM (scanning electronmicroscope). The preparation of the sample includes vaporization with gold, and then the samples are placed in aspecial chamber where they are bombarded with electrons and the structure is observed on a monitor. Depending onthe type of error in rubber products, they can be divided into those related to material technology and those causedby external impurities. Those related to the manufacturing technology can be different, agglomerations and variouschemical compounds can occur during mixing.
由聚合物材料制成的产品是通过在温度的影响下,在某些情况下,在高压的影响下,将原材料转化为液态并填充模腔而获得的。这种转变往往是有问题的,因为当转变为液态时,材料中开始发生不可逆的化学过程,而反结晶过程必须在很短的时间内完成。这个问题在橡胶制品中尤为明显。在制作原料混合物时,必须遵循有关混合速度、添加组分的顺序和过程本身持续时间的程序。在混合参数选择不当的情况下,可能会在产品结构中发生结块,这可能会对产品本身的开发产生负面影响。当生橡胶开始过渡到液相并充满模腔时,与工具接触的层形成最终的结构和形状。如果化学系统不平衡,即溢出速度不平衡,则可能发生橡胶未填充模腔而产生废料的情况。另一个问题是,如果刀具的闭合速度很高,可能会出现材料的松散结构或结构上的某种缺陷。对于这种现象,必须考虑到溢出的速度总是高于关闭工具的速度。在硫化温度和硫化剂选择不当的情况下,某些化合物也可能出现,对产品的性能产生负面影响。此外,必须特别注意工作环境,因为在产品结构中经常会发现与混合和压制程序有关的外部物体。材料结构的释放属于一组特殊的测试,并且总是伴随着产品的破坏。按检查类型分属于目视控制,又按光学放大程度分宏观和微观检查。眼睛检查属于显微镜检查,用于检查产品的外观,这种类型的检查方便,因为它是快速和可靠的。橡胶的显微检查是非常复杂的,因为橡胶不是透明的材料。因此,在SEM(扫描电子显微镜)上对结构进行检查。样品的制备包括用金汽化,然后将样品放置在特殊的室中,在那里用电子轰击,并在监视器上观察其结构。根据橡胶制品中的误差类型,可分为与材料工艺有关的误差和由外部杂质引起的误差。与制造技术相关的可以是不同的,在混合过程中可能会发生结块和各种化学化合物。而随着压力的增加,可能会出现通风结构。结构上最常见的错误是产品内部出现异物。这个问题可以通过明确的混合和压制程序来解决,也可以通过程序本身的自动化来解决,从而将人为错误减少到最低限度。
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引用次数: 0
CORRELATION BETWEEN OSCILLATORY MOTION AND GRAVITY REGARDED AS EDUCATIONAL CONTENT 振荡运动与重力的相关性被视为教育内容
Pub Date : 2022-09-30 DOI: 10.35120/kij5403527k
Ivana Krulj
The author of the paper has been teaching physics at Academy of technical and educational vocationalstudies for the past seven years, of which two academic years took place during the Covid-19 pandemic. Internetresources have been applied beforehand throughout the entire period, but with fully online teaching, it gainedparticular importance. Educational approaches developed for online classes required students’ activities that wouldfurther motivate them to study. In the academic year 2021/22, educational contents were enhanced with additionallinking of certain educational contents, which resulted from the obvious need to make the material as interesting aspossible, and to awaken curiosity about the contents. In this paper it is shown how a specific digital simulation canbe used for a teaching topic for which it was not originally intended, and it was also shown that in this way a usefulcorrelation of different teaching contents can be realized. The significance of the above-mentioned correlation isreflected in the fact that it requires a teaching approach that leads to more effective learning process in class as wellas to greater motivation and greater activation of students in the class. A simulation related to the oscillation of amathematical pendulum is described in this paper, i. e. its ability to choose different strengths of gravitational fieldsin which the pendulum oscillates, i. e. different gravitational accelerations. It was researched how students thinkwhen for the given phenomena a zero gravity is approximated. It was researched whether the students realized achange in their activities both in class and in their motivation for work. It is interesting that only after theimplementation of weightlessness as an educational content in the existing educational content on oscillatorymotion, the teacher saw certain alternative conceptions that some students built when they were studying aboutoscillations.
该论文的作者在过去的七年里一直在技术和教育职业研究学院教授物理,其中有两个学年是在Covid-19大流行期间。在整个过程中,互联网资源已经预先应用,但在完全在线教学中,它变得尤为重要。为在线课程开发的教育方法要求学生进行能够进一步激励他们学习的活动。在2021/22学年,教育内容得到了加强,增加了某些教育内容的链接,这是由于显然需要使材料尽可能有趣,并唤醒对内容的好奇心。本文展示了如何将特定的数字仿真用于原本不打算用于的教学主题,并且还显示了通过这种方式可以实现不同教学内容的有用关联。上述相关性的意义体现在它需要一种教学方法,使课堂上的学习过程更有效,使学生在课堂上更有动力、更活跃。本文描述了数学摆振荡的模拟,即它能够选择不同强度的引力场,使摆振荡,即不同的重力加速度。研究了当给定的现象近似为零重力时,学生们是如何思考的。研究了学生是否意识到他们在课堂上的活动和工作动机的变化。有趣的是,只有在现有的振荡运动教育内容中,将失重作为教育内容实施后,老师才看到一些学生在学习振荡时建立的某些另类概念。
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引用次数: 0
CRITICAL EQUIPMENT QUALIFICATION PARAMETERS AFFECTING THE HOMOGENIZATION PROCESS OF MEDICAL CANNABIS SEMI-SOLID PHARMACEUTICALS 影响医用大麻半固体药物均质过程的关键设备鉴定参数
Pub Date : 2022-09-30 DOI: 10.35120/kij5404669c
Ivana Cocovska, E. Janevik-Ivanovska
The medical cannabis has been used for many of years for medicinal purpose, in different pharmaceuticalformulation, mostly as a magistral preparation for the relief of pain in cancer patients or chronical painful diseases.Over than 540 substances were found from which more than 100 that have been found to be cannabinoids due totheir similar chemical structure. The component with the most psychotropic action is Δ9 -tetrahydrocannabinol (Δ9 -THC), and the major non-psychoactive ingredient is cannabidiol (CBD). Δ9 -tetrahydrocannabinol firstly wasisolated in 1969 by Robert Mechoulm and Yechiel Gaoni. In 2003 World Health Organization put Δ9 -tetrahydrocannabinol in Schedule IV of the convention. Several therapeutic indications relate to the Δ9 -THC andCBD as analgesia, inflammatory and neurodegenerative diseases, and many other cases. In some studies, there arereported safety concerns about the registered side effects of Δ9 - THC as a psychoactive. For that reason, the legalusage of cannabis for medicinal purposes and for recreational use is regulated differently. The most relevantexplanation is related to the not enough sufficient results and data obtained from the pharmacokinetic studies andresearch in pharmacological behavior. Extracts of cannabis was used from many years ago. Nowadays inpharmaceutical industry as the development of technology there are many dosage forms in where extracts,cannabinoids, flower are used. Medicinal cannabis products can come in many different forms, including capsules,drops, chewable, creams, crystals, flower, lozenges, oil (most common), oro-mucosal sprays, tinctures and manymore. Also, there are synthetic analogs to nature cannabinoids in pharmaceutical market. In this study will bediscussed about production of semisolid pharmaceutical forms obtained from medical cannabis. They are producedin pharmaceutical grade equipment, high-pressure homogenizer mixer. In this study it will be discussed about theprocess of equipment qualification. Firstly, by the user requirement specification, design qualification protocol wasapproved. Then factory acceptance test was performed in production site of equipment and site acceptance test wasperformed in costumer’s site. Then installation qualification protocol was look through and then operationalqualification protocol also. All the qualification protocols were approved by both sides. In different qualificationprotocols, different tests were performed, and they are explained separately. During the qualification process, thereare considered some of the parameters which later during the production process can affect in the quality of finishedproducts. These parameters are called critical process parameters and accent will be put on this process parametersthat are with a critical effect on quality of the final products. This critical process parameters were considered andconcluded from qualification protocols where all the parameters that can affect quality of the product weresepara
多年来,医用大麻以不同的药物配方用于医疗目的,主要是作为缓解癌症患者疼痛或慢性疼痛疾病的主要制剂。超过540种物质被发现,其中超过100种被发现是大麻素,因为它们的化学结构相似。最具精神作用的成分是Δ9 -四氢大麻酚(Δ9 -THC),主要的非精神活性成分是大麻二酚(CBD)。Δ9 -四氢大麻酚于1969年由Robert Mechoulm和yechel Gaoni首次分离得到。2003年,世界卫生组织将Δ9 -四氢大麻酚列入公约附表四。一些治疗指征与Δ9 -THC和cbd有关,如镇痛、炎症和神经退行性疾病,以及许多其他病例。在一些研究中,有关于Δ9 -四氢大麻酚作为一种精神活性物质的副作用的安全报道。出于这个原因,大麻的药用和娱乐用途的合法使用受到不同的监管。最相关的解释与药代动力学研究和药理学行为研究的结果和数据不够充分有关。许多年前就开始使用大麻提取物。如今,在制药工业中,随着技术的发展,有许多剂型的提取物,大麻素,花被使用。药用大麻产品可以有许多不同的形式,包括胶囊、滴剂、咀嚼剂、面霜、晶体、花、含片、油(最常见)、口腔粘膜喷雾剂、酊剂等等。此外,在医药市场上也有天然大麻素的合成类似物。在本研究中,将讨论从医用大麻中获得的半固体药物形式的生产。它们是在制药级设备、高压均质机、混合器中生产的。本研究将讨论设备鉴定的过程。首先,根据用户需求说明书,批准设计确认方案。然后在设备生产现场进行工厂验收,在客户现场进行现场验收。然后是安装确认协议然后是操作确认协议。所有的鉴定方案都得到了双方的认可。在不同的鉴定方案中,进行了不同的测试,并分别进行了说明。在确认过程中,考虑了一些参数,这些参数在以后的生产过程中会影响成品的质量。这些参数被称为关键工艺参数,重点将放在对最终产品质量有关键影响的工艺参数上。这些关键工艺参数被考虑并从确认协议中得出结论,其中所有可能影响产品质量的参数都被单独检查。
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引用次数: 0
IRREGULARITIES IN THE USE OF THE MODERN SPANISH LANGUAGE 现代西班牙语使用的不规则性
Pub Date : 2022-09-30 DOI: 10.35120/kij5405787a
Natasha Aleksoska
The language errors could potentially hinder the transmission of information and disturb theconcretization of the act of communication. In the contemporary context, many factors exercise influence on thelanguage especially the social media triggering disregard of the linguistic norms, devaluing the correct use of thelanguage and disrupting the normal flow of communication. These irregularities in the use of the Spanish languageare known as language vices. The subject of this paper is a broad view of the irregularities (that could be of differentgrammatical nature) that could result from the improper use of the Modern Spanish language and encompasses thedefinition, review of the most common types of language vices (pleonasm, solecism, amphibology, barbarism,archaism, and neologism) supported by a series of examples excerpted from relevant sources among whichOrtografía de la lengua Española (RAE:2010). Diccionario panhispánico de dudas (RAE:2005), Gran diccionariode sinónimos, voces afines e incorrecciones (Fernando Corripio, Bruguera, 1979), etc. The purpose of the paper is,in absence of Spanish grammar(s) in Macedonian language and published comparative papers in particular in thefield of lexicology, to fill to some extant the vacuum and shed light on the language vices in the Modern Spanishlanguage, thus arousing the interest of the Macedonian linguists, especially those with knowledge of Spanish forfuture more profound research and their systematization.
语言错误有可能阻碍信息的传递,扰乱交际行为的具体化。在当代语境下,许多因素对语言产生了影响,尤其是社交媒体,引发了对语言规范的漠视,贬低了语言的正确使用,扰乱了正常的交流流程。这些西班牙语使用中的不规则现象被称为语言恶习。本文的主题是对现代西班牙语不当使用可能导致的不规则现象(可能具有不同的语法性质)的广泛看法,包括定义,审查最常见的语言恶习类型(pleonasm, solecism, amphibology, barbarism,古语和新词),并从whichOrtografía de la lengua Española (RAE:2010)中摘录的一系列例子提供支持。《词典》panhispánico de dudas (RAE:2005)、《大词典》sinónimos、《声音与错误》(Fernando Corripio, Bruguera, 1979)等。本文的目的是为了填补马其顿语语法的空白,特别是在词词学领域发表的比较论文,在一定程度上填补现代西班牙语的空白,揭示现代西班牙语的语言缺陷,从而引起马其顿语言学家,特别是具有西班牙语知识的语言学家的兴趣,以便将来进行更深入的研究和系统化。
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Knowledge International Journal
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