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Prevalence of Helicobacter pylori infection and its Associated Risk Factors among symptomatic Residents of Sulaimani city, Kurdistan region, Iraq, 2020 2020年伊拉克库尔德斯坦地区苏莱曼尼市有症状居民幽门螺杆菌感染率及其相关危险因素
Pub Date : 2021-07-07 DOI: 10.24017/SCIENCE.2021.1.1
Seerwan Hama Rashid Ali, S. Salih, Taib Ahmed Hama Sour, G. M. Raouf, Araz Latif Rahim
Helicobacter pylori (H. pylori) bacteria are a microaerobic Gram negative that colonizes in the gastric and duodenum of human. It can cause prolong infection in the human life if not treated. Many of the studies showed that infection by H. pylori can cause some important gastrointestinal illness, such as peptic ulcer, chronic gastritis, gastric adenocarcinoma and mucosa associated lymphoid tissue lymphoma. Recurrence is generally considered as H. pylori recrudescence infection after one year of eradicated treatment. There are many factors involved in the H pylori reinfection, such as the epidemiology of H. pylori infection, condition of the live, development of economical state, and health conditions. The Objectives of this study were to estimate the incidence and determine the risk factors of infection by H. pylori bacteria in dyspeptic patients in Sulaimani city. And the Aims are to estimate prevalence of the Helicobacter pylori and patients’ characteristics in Sulaimani city. This is a cross-sectional study, using a Urea breath test or stained the gastric sample with Giemsa stain, which is including adult participants aged (12-87) years during the period starting from 1 January until 31 December 2020 on Iraqi male and female patients were visiting –Center for Gastroenterology and Hepatology in Sulaimani, city, Iraq. Three hundred and four patients were included, all of them underwent Urea breath test only but eighty-one of the participants underwent endoscopy and stained the gastric sample with Giemsa stain. Urea breath test for Helicobacter pylori was positive in54.9% which have significant correlation with risk factor findings. Results: the incidence rate of H. pylori infection in our study is 54.9%, and mean age of the study participants was (40.49 ±16.39) one hundred and ninety-one cases 62.8% were female and 113 cases 37.2%were male. Infection by H. pylori bacteria is rife in dyspeptic patients; and is more common in the age group of 31-40 years. One of noninvasive test to diagnosis H. pylori is Urea breath test.  In conclusions the rate of helicobacter pylori infection in our study is 54.9% among the symptomatic patients, and the overall incidence of H. pylori UBT and Giemsa stain detection rate were 73.4 and 26.6% respectively.  
幽门螺杆菌(Helicobacter pylori, H. pylori)是一种微需氧革兰氏阴性菌,定植于人的胃和十二指肠。如果不及时治疗,可延长人的感染时间。许多研究表明,幽门螺杆菌感染可引起一些重要的胃肠道疾病,如消化性溃疡、慢性胃炎、胃腺癌和粘膜相关淋巴组织淋巴瘤。复发一般认为是根除治疗一年后幽门螺杆菌复发性感染。影响幽门螺杆菌再感染的因素很多,如幽门螺杆菌感染的流行病学、生活状况、经济发展状况、卫生状况等。本研究的目的是估计苏莱曼尼市消化不良患者幽门螺杆菌感染的发生率和确定危险因素。目的是估计苏莱曼尼市幽门螺杆菌的患病率和患者特征。这是一项横断面研究,使用尿素呼吸试验或用吉姆萨染色法对胃样本进行染色,其中包括从2020年1月1日至12月31日期间访问伊拉克苏莱曼尼市胃肠病学和肝病学中心的伊拉克男性和女性患者,年龄为(12-87)岁。共纳入384例患者,所有患者均进行尿素呼吸试验,但其中81例患者进行了内窥镜检查并对胃样本进行了吉氏染色。尿素呼气试验幽门螺杆菌阳性率为54.9%,与危险因素有显著相关性。结果:本研究中幽门螺杆菌感染率为54.9%,平均年龄为(40.49±16.39)岁,女性191例,62.8%,男性113例,37.2%。幽门螺杆菌感染在消化不良患者中很常见;多见于31-40岁年龄组。尿素呼气试验是诊断幽门螺杆菌的无创检查之一。结论本研究有症状患者幽门螺杆菌感染率为54.9%,幽门螺杆菌UBT总感染率为73.4,吉姆萨染色检出率为26.6%。
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引用次数: 0
Performance Analysis: AI-based VIST Audio Player by Microsoft Speech API 性能分析:基于微软语音API的基于ai的VIST音频播放器
Pub Date : 2021-07-07 DOI: 10.24017/SCIENCE.2021.1.3
R. Ibrahim
Speech recognition has gained much attention from researchers for almost last two decades. Isolated words, connected words, and continuous speech are the main focused areas of speech recognition. Researchers have adopted many techniques to solve speech recognition challenges under the umbrella of Artificial Intelligence (AI), Pattern Recognition and Acoustic Phonetic approaches. Variation in pronunciation of words, individual accents, unwanted ambient noise, speech context, and quality of input devices are some of these challenges in speech recognition. Many Application Programming Interface (API)s are developed to overcome the issue of accuracy in a speech-to-text conversion such as Microsoft Speech API and Google Speech API. In this paper, the performance of Microsoft Speech API is analyzed against other Speech APIs mentioned in the literature on the special dataset (without background noise) prepared. A Voice Interactive Speech to Text (VIST) audio player was developed for the analysis of Microsoft Speech API. VIST audio player creates runtime subtitles of the audio files running on it; the player is responsible for speech to text conversion in real-time. Microsoft Speech API was incorporated in the application to validate and make the performance of API measurable. The experiments proved the Microsoft Speech API more accurate with respect to other APIs in the context of the prepared dataset for the VIST audio player. The accuracy rate according to the precision-recall is 96% for Microsoft Speech API, which is better than previous ones as mentioned in the literature.
近二十年来,语音识别受到了研究人员的广泛关注。孤立词、连接词和连续语音是语音识别的主要研究领域。在人工智能(AI)、模式识别和声学语音方法的保护下,研究人员采用了许多技术来解决语音识别的挑战。单词发音的变化、个人口音、不需要的环境噪声、语音上下文和输入设备的质量是语音识别中的一些挑战。开发了许多应用程序编程接口(API)来克服语音到文本转换中的准确性问题,例如Microsoft Speech API和谷歌Speech API。本文在准备好的特殊数据集(无背景噪声)上,对比文献中提到的其他Speech API对Microsoft Speech API的性能进行了分析。为分析微软语音API,开发了语音交互语音转文本(VIST)音频播放器。VIST音频播放器创建运行在它上面的音频文件的运行时字幕;玩家负责实时的语音到文本的转换。在应用程序中加入了微软语音API,以验证和测量API的性能。实验证明,在准备好的VIST音频播放器数据集的背景下,Microsoft Speech API相对于其他API更准确。根据precision-recall, Microsoft Speech API的准确率为96%,优于之前文献中提到的。
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引用次数: 0
Utilizing Statistical Tests for Comparing Machine Learning Algorithms 利用统计测试比较机器学习算法
Pub Date : 2021-07-07 DOI: 10.24017/SCIENCE.2021.1.8
H. Hamarashid
The mean result of machine learning models is determined by utilizing k-fold cross-validation. The algorithm with the best average performance should surpass those with the poorest. But what if the difference in average outcomes is the consequence of a statistical anomaly? To conduct whether or not the mean result differences between two algorithms is genuine then statistical hypothesis test is utilized. Using statistical hypothesis testing, this study will demonstrate how to compare machine learning algorithms. The output of several machine learning algorithms or simulation pipelines is compared during model selection. The model that performs the best based on your performance measure becomes the last model, which can be utilized to make predictions on new data. With classification and regression prediction models it can be conducted by utilizing traditional machine learning and deep learning methods. The difficulty is to identify whether or not the difference between two models is accurate.
机器学习模型的平均结果是利用k-fold交叉验证确定的。平均性能最好的算法应该超过平均性能最差的算法。但是,如果平均结果的差异是统计异常的结果呢?为了判断两种算法之间的平均结果差异是否真实,使用统计假设检验。使用统计假设检验,本研究将演示如何比较机器学习算法。在模型选择过程中比较几种机器学习算法或仿真管道的输出。根据您的性能度量,表现最好的模型将成为最后一个模型,该模型可用于对新数据进行预测。有了分类和回归预测模型,可以利用传统的机器学习和深度学习方法进行预测。困难在于确定两个模型之间的差异是否准确。
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引用次数: 5
Psychological hardiness and its relationship to health awareness Among Kurdish people in Kurdistan Region during the pandemic of Covid-19. 新冠肺炎大流行期间库尔德斯坦地区库尔德人心理抗寒性及其与健康意识的关系
Pub Date : 2021-07-07 DOI: 10.24017/SCIENCE.2021.1.4
T. Mohammed, Hanaw Hasan Mohammedhkan, Delan Jamal Qader, Fatah Hama Rahim
Objective: Like Iraq and neighboring countries, the Kurdistan region was affected by the epidemic which gradually led to a lockdown in March and April and a wide-spread disruption of people’s life and activates. In this study, the researcher investigated the psychological hardiness and its relation to health awareness among citizens of the Kurdistan region during the Corona epidemic. Methods: This study followed a cross-sectional design quantitative survey that was conducted online from 1 to 18 April 2020. After two months of lockdown due to coronavirus pandemic in the Kurdistan Region. A questionnaire of 25 questioners to measure psychological hardiness, later the researchers got the psychometric qualities. Results: The researcher observed high psychological hardiness levels in the study, because of the Covid-19 pandemic. It has shown the non-significant association between psychological hardiness and health awareness and identified several significant factors associated with this psychological hardiness and health awareness. Conclusion: Using contractive tools, the study showed that the psychological hardiness of the citizens of the Kurdistan region is at a low level during the COVID-19 pandemic. The results could serve as a framework for future research to examine the influence of the pandemic on the population's association of psychological hardiness with health awareness.          
目的:与伊拉克及周边国家一样,库尔德斯坦地区也受到疫情影响,3、4月份逐步实行封锁,民众生活和活动受到广泛干扰。在这项研究中,研究人员调查了库尔德斯坦地区公民在冠状病毒流行期间的心理抗寒性及其与健康意识的关系。方法:本研究采用横断面设计定量调查,于2020年4月1日至18日在线进行。在库尔德斯坦地区因冠状病毒大流行而封锁了两个月之后。通过对25名被试者的心理耐受力进行问卷调查,得到被试者的心理测量素质。结果:由于Covid-19大流行,研究人员在研究中观察到较高的心理抗逆性水平。结果表明,心理抗寒性与健康意识之间存在不显著相关性,并确定了与心理抗寒性和健康意识相关的几个显著因素。结论:使用收缩工具进行的研究表明,在2019冠状病毒病大流行期间,库尔德斯坦地区公民的心理适应力处于较低水平。这些结果可以作为未来研究的框架,以检查大流行对人口心理耐受性与健康意识之间关系的影响。
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引用次数: 0
Effect of Folic Acid by injection and supplementary on growth and puberty of Karadi male lambs 注射和补充叶酸对卡拉迪公羔羊生长发育的影响
Pub Date : 2021-07-07 DOI: 10.24017/SCIENCE.2021.1.5
Ismael Othman Karim
The present study is carried out to study the effect of Folic Acid (FA) by injection and supplementary on animal body weight gain, Testes volume before slaughtering, Testes volume after slaughtering, Testosterone concentration in blood, and FA concentration in blood. Twenty-five (25) Karadi male lambs five months aged and the average weight was 24.54 ±1.92 kg were used in this experiment. The animals weighed after three months of treatment to get animal increased live weight, The testes measured after one, two, and three months of treatment to calculate testes volume, testosterone, and FA concentration level in the blood were taken after one, two, and three months of treatment. The present study demonstrated that animal body weight, animal body weight gain, and total body weight gain significantly not increased (p>0.05). Testicular length, and testicular circumference not increased (p>0.05) after 1st, 2nd, and 3rd months after treatment, and after slaughtering. However, testicular high increased (p<0.05) after each month of treatment and slaughtering. Testosterone concentration in the blood significantly not different (p>0.05) reported between treatments after the 1st, 2nd, and 3rd months of treatment. FA concentration in the blood significantly increased (p<0.05) when used 3 and 6 mg FA by injection compared to control after 1st and 2nd months of treatment. However, blood FA concentration increased (p<0.05) when used FA 6mg/ml as an injection after the 2nd month of treatment compared to control. While using FA by supplementation and injection significantly (p>0.05) on the diameter and circumference of seminiferous tubules, germ cells thickness, and lumen diameters.
本研究旨在研究注射和补充叶酸(FA)对动物体重增加、屠宰前睾丸体积、屠宰后睾丸体积、血液中睾酮浓度和血液中FA浓度的影响。本实验使用了25只五个月大的卡拉迪公羊羔,平均体重为24.54±1.92kg。动物在治疗三个月后称重,以获得动物增加的活体重。在治疗一个月、两个月和三个月之后测量睾丸,以计算睾丸体积、睾酮和血液中FA浓度水平。本研究表明,动物体重、动物体重增加和总体重增加均未显著增加(p>0.05)。治疗后第1、2、3个月和屠宰后,睾丸长度和睾丸周长均未增加(p>0.05)。然而,在治疗的第1个月、第2个月和第3个月后,两次治疗之间的睾丸高度增加(p0.05)。血中FA浓度在曲精管直径和周长、生殖细胞厚度和管腔直径上显著增加(p0.05)。
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引用次数: 0
Engine Oil Deterioration based on the Viscosity, flash point and fire point for Different Trip Length 不同行程下机油粘度、闪点和燃点的劣化
Pub Date : 2021-07-07 DOI: 10.24017/SCIENCE.2021.1.2
Dana Hameed
Fresh engine oils or engine lubricants lose some of their properties during service, engine lubricant deterioration leads to change in oil properties, which ultimately have effect on engine overall performance.  Therefore, it is very important to characterize used engine lubricants at different using conditions to check the performance and ability of existing oils, which in turn protects engine parts and also designs new formulations to produce better type of engine oil or improve the existing oil. Therefore, optimizing engine oil lubricant changing time is very important for reducing environmental impact but renewing engine lubricant before it is due rises a customer’s cost. In this study, the most significant parameters such as kinematic viscosity, flash point and fire point were chosen to determine the changes and deterioration in engine oil properties. The oil samples were multigrade fully synthetic with SAE gradation 10W-30 grand ecodrive is used in 5 different passenger cars. Having information about these properties are crucial chemical and physical behaviours of engine oils and for keeping engine’s lifecycle. The test results of this work show that after 10,000 km, 10W-30 Delta NL motor oil brand (special synthetic with API SL) oil properties such as kinematic viscosity at cold start, 40 °C and 100 °C decreased 22.92%, 23.61% and 22.92% respectively. In addition, both flash point and fire point decreased 15.6% and 14.22% consecutively for the base properties, and according to the test results this type of engine oil is suitable to use for 10,000 km.
新鲜的发动机油或发动机润滑油在使用过程中会失去一些特性,发动机润滑油的变质会导致机油特性的变化,最终影响发动机的整体性能。因此,在不同的使用条件下对二手发动机润滑油进行表征,以检查现有机油的性能和能力,从而保护发动机部件,并设计新的配方以生产更好类型的发动机机油或改进现有机油是非常重要的。因此,优化发动机润滑油更换时间对于减少对环境的影响是非常重要的,但提前更换发动机润滑油会增加客户的成本。在本研究中,选取了运动粘度、闪点和燃点等最重要的参数来确定发动机油性能的变化和劣化。油样是多级合成的,SAE等级为10W-30,在5种不同的乘用车中使用了grand ecodrive。掌握这些特性的信息是至关重要的化学和物理行为的发动机油和保持发动机的生命周期。本工作的试验结果表明,10W-30台达NL牌机油(API SL特种合成)在行驶1万公里后,冷启动、40℃和100℃时的运动粘度等机油性能分别下降22.92%、23.61%和22.92%。此外,基础性能闪点和燃点分别下降15.6%和14.22%,试验结果表明,该型机油适合使用1万公里。
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引用次数: 4
Outcome of Excision with Primary Midline Closure for Sacrococcygeal Pilonidal Sinus Disease 骶尾椎毛窦疾病一期中线闭合切除的疗效
Pub Date : 2020-12-12 DOI: 10.24017/science.2020.ichms2020.3
Bahzad Waso Hamad
Sacrococcygeal Pilonidal sinus disease is common chronic inflammatory disease affecting chiefly young adult male . It cause much discomfort and morbidity and affect negatively the quality of life of patients. There are various techniques of surgical treatment for the chronic sinuses but still there is no gold standard one. The aim of this study to report our experience with excision and midline closure technique of chronic Sacrococcygeal Pilonidal sinus disease and to identify the outcome of the procedure for postoperative wound complications and recurrence rate. This is a retrospective study with telephone contact and review of 36 patients operated for Sacrococcygeal pilonidal sinus disease from January 2011 through January 2016 under care of one consultant surgeon (the Author) in Public and Private Hospitals in Rania, Sulaimani, Iraq. Inclusion criteria was all patients with chronic midline located sinuses without evidence of acute inflammation. Exclusion criteria was all infected ,off midline located sinuses and recurrent sinuses. Elliptical Excision of the sinuses with primary midline closure over a vacuum drainage performed. End point of this study was rate of wound complications and recurrence of sinus. Thirty six patients with median age 22 years (range 14-40) with 24/12 male /female ratio. Median follow up was 24 months (12 - 66 months), the recurrence occurred in 3/36 ( 8.3%) patients at a median of 12 months (range 5 - 48), failure of treatment in 5/36 (13.9%) patients, and postoperative wound complications was seen in 5/36 ( 13.9%) patients. In the conclusion, excision and primary midline closure is simple, effective and preferable procedure for management of uncomplicated Sacrococcygeal pilonidal sinus disease associated with early wound healing and low rate of postoperative wound complications and recurrence rate.
骶尾骨毛窦病是一种常见的慢性炎症性疾病,主要影响年轻成年男性。它会引起许多不适和发病率,并对患者的生活质量产生负面影响。慢性鼻窦炎的手术治疗方法多种多样,但仍没有一个黄金标准。本研究的目的是报告我们的经验,切除和中线关闭技术治疗慢性骶尾椎毛窦疾病,并确定手术的结果,术后伤口并发症和复发率。这是一项回顾性研究,通过电话联系并回顾了2011年1月至2016年1月在伊拉克苏莱曼尼拉尼的公立和私立医院由一名顾问外科医生(作者)治疗的36例骶尾椎毛毛窦疾病患者。纳入标准为所有无急性炎症证据的慢性中线鼻窦患者。排除标准为所有感染、离中线鼻窦和复发鼻窦。椭圆切除鼻窦,主要中线封闭在真空引流。本研究的终点是伤口并发症和鼻窦复发率。36例患者中位年龄22岁(14-40岁),男女比例为24/12。中位随访时间为24个月(12 ~ 66个月),3/36(8.3%)例患者复发,中位随访时间为12个月(5 ~ 48个月),5/36(13.9%)例患者治疗失败,5/36(13.9%)例患者出现术后伤口并发症。综上所述,骶尾椎毛突窦切除和初级中线闭合是治疗无并发症的骶尾椎毛突窦疾病的一种简单、有效和较好的方法,且伤口愈合早,术后伤口并发症和复发率低。
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引用次数: 0
Knowledge, Attitude and Practice of Medical Students of Sulaimani Regarding Modern Lifestyle And Its Effect On Health 苏莱曼尼医科学生对现代生活方式的认识、态度和实践及其对健康的影响
Pub Date : 2020-12-12 DOI: 10.24017/science.2020.ichms2020.6
B. Ali, S. Mohammed, Shajwan Akram, Sayad Salar, Lezan Baxtiar, Lawen Ismail, Shad Nawzad
The objectives of this study are to assess level of knowledge, attitude and practice of medical students about modern lifestyle and its impact upon health, in association with different colleges. A cross sectional study was conducted among 420 students, in a convenient sampling way, Data collected from 18th to 22nd of September 2019 in a self-administrated manner from four different medical colleges (Medicine, Dentistry, Pharmacy and Veterinary.) in university of Sulaimani. Data entered on Excel sheets and analyzed with SPSS program version 22. Chi square was used to get the association P value equal and less than (0.05) regarded statistically significant. Most of the students (82.1%) had heard about a modern lifestyle with highest percentage of participants (90.5%) from college of medicine, and (69.3%) knew that technology has a major role in creating a modern lifestyle, with a significant P value of (0.001). Nearly half of the students (54.5%) believed to be living a modern lifestyle and most of them (66.2%) were from college of dentistry. About (49.5%) of students believed that financial status can sometimes put limits on lifestyle choice with most of them (52.7%) being from college of dentistry  with p value of (0.001). Majority of students (995%) used social media with most of them (97.4%) being from college of medicine. Nearly (66%) of participants didn’t exercise and highest percentage (78.1%) from college of pharmacy with a significant (P value 0.007). Participants in general had good knowledge and positive attitude regarding the topic, but they had a negative practice with managing stress, time and depression and had negative habits regarding exercise and having healthy diet. In addition college of medicine had highest knowledge and attitude among the four medical colleges, but regarding the practice college of pharmacy was the best.
本研究的目的是评估不同大学医学生对现代生活方式及其对健康影响的知识、态度和实践水平。以方便的抽样方式对420名学生进行了横断面研究,数据于2019年9月18日至22日以自我管理的方式从苏莱曼尼大学的四所不同医学院(医学、牙科、药学和兽医)收集。数据输入Excel表中,并使用SPSS程序版本22进行分析。采用卡方法得到的关联P值等于或小于(0.05),具有统计学意义。大多数学生(82.1%)听说过现代生活方式,医学院的参与者比例最高(90.5%),(69.3%)知道技术在创造现代生活方式中发挥着重要作用,P值为(0.001)。近一半的学生(54.5%)认为过着现代生活方式。其中大多数学生(66.2%)来自牙科学院。约(49.5%)的学生认为,经济状况有时会限制他们的生活方式选择,其中大多数(52.7%)来自牙科学院,p值为(0.001)。大多数学生(995%)使用社交媒体,其中大多数学生(97.4%)来自医学院。近(66%)的参与者没有锻炼,最高比例(78.1%)来自药学院,有显著性差异(P值0.007)。参与者总体上对这个话题有很好的知识和积极的态度,但他们在管理压力、时间和抑郁方面有负面的做法,在锻炼和健康饮食方面有负面习惯。此外,在四所医学院校中,医学院的知识和态度最高,但在药学实践学院方面表现最好。
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引用次数: 1
Patient’s Information Toward Some Modifiable Risk Factors of Ischemic Heart Disease 缺血性心脏病一些可改变危险因素的患者信息
Pub Date : 2020-12-12 DOI: 10.24017/science.2020.ichms2020.4
Bayan Omar Sharif, Aras Hamad Rasul, Osman Ibrahim Mahmud, Farman Nuri Abdulla
Ischemic heart disease (IHD), , is the condition of heart problems, caused by narrowed coronary arteries that supply oxygenated blood to the heart muscle. There is a shortage of study of bachelor students. The goal of this research was directed to assess level of patient’s information toward some modifiable risk factors of IHD at Rania teaching hospital in Kurdistan region of Iraq during the period of (20th October 2019 - 10th February 2020). A non- probability purposive sample of (143) patients; the study instrument was constructed of total (42) items for the purpose of data collection. The content validity of the instrument was determined through a panel of (12) experts. Reliability of the instrument was determined through the use of internal consistency reliability (split half) approach which was estimated as r = (0.83) the data were collected through the use of interview technique (face to face approach), the computer files is used to organizing and coding it. The data analyzed by Statistical approaches which includes: descriptive and inferential statistical and chi- square, data analysis (SPSS version 25). The outcome showed that most of the sample rang from the age (25-40) years and most of them were male from urban, more than half of them were unemployed but nearly half of them were graduated from primary school. 32.2% of them diagnosed by cardiovascular disease. However more than half of them had a high level of information about IHD as a general, and the TV was the first source of their information but more than half of them were overweight, 65% did not do regular exercise, 52.4% were relatively stressful. Also, the study demonstrated that there is no significant association between socio demographic data and level of patient’s information toward some modifiable risk factors of IHD, with age, gender, educational level and occupation with IHD, at p value greater than 0.05. The study recommended to ministry of health and directorate of health in Rania city to develop and supervise the center of dietary regimen and halls of exercise for the people to implement their information and practice it
缺血性心脏病(IHD)是一种心脏问题,由向心肌供应含氧血液的冠状动脉狭窄引起。本科学生的学习不足。本研究的目的是评估2019年10月20日至2020年2月10日期间伊拉克库尔德斯坦地区拉尼亚教学医院患者对IHD一些可改变风险因素的信息水平。143例患者的非概率目的样本;为了收集数据,研究仪器共由42个项目组成。该仪器的内容效度是通过(12)个专家小组确定的。采用内部一致性信度法(劈半法)确定仪器的信度,估计r =(0.83),采用访谈法(面对面法)收集数据,利用计算机文件进行组织编码。数据分析的统计方法包括:描述性和推断性统计和卡方,数据分析(SPSS 25版)。结果表明,样本的年龄大多在25-40岁之间,以城市男性居多,超过一半的人没有工作,但近一半的人小学毕业。其中32.2%诊断为心血管疾病。然而,他们中超过一半的人对IHD的了解程度很高,电视是他们信息的第一来源,但超过一半的人超重,65%的人没有定期锻炼,52.4%的人压力相对较大。同时,本研究还发现,对于IHD的一些可改变的危险因素,如年龄、性别、受教育程度、IHD的职业,社会人口学数据和患者信息水平之间没有显著的相关性,p值大于0.05。该研究建议拉尼亚市卫生部和卫生局建立和监督饮食养生中心和锻炼大厅,以便人们实施和实践他们的信息
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引用次数: 0
Immunological Approaches and Different Strategies for Vaccine Development against SARS-COV-2 SARS-COV-2疫苗研制的免疫学途径和不同策略
Pub Date : 2020-12-12 DOI: 10.24017/science.2020.ichms2020.10
M. Babakir-Mina
Globally, SARS-CoV-2 outbreak is considered as pandemic viral infection by the World Health Organization (WHO). In the immunological response aspect, a very limited understanding has been progressed, mainly innate and adaptive immunity responses toward the virus. SARS-COV-2 causes severe respiratory disease and sometimes ended with the death. The body of the patients has ability to develop the immunity to cure the patient and more importantly both humoral and cellular immunity have studied against SARS-COV-2. There are different immune responses against the viral infection as it has seen in other previous diseases such as SARS-COV and MESR. On the base on immune response detected in recovered patients, scientists have started to develop the vaccines. Moreover, there are different strategies that used by researchers and pharmacological companies to develop vaccines including attenuated or killed viruses, RNA of a spike protein, and vector expressing a particular protein of the virus. The common antibodies have detected to work against SARS-COV-2 in sera of infected or recovered patients are immunoglobin G ( IgG) and immunoglobin M (IgM). The sera of patients recovered from COVID-19, after tittering of immunoglobulins (IgG titer) can be used for either treatment of disease or prophylaxis of infection by SARS-COV-2. This study gives an update on the current immunological approaches and vaccination strategies for the emerging SARS-COV-2, and discusses the challenges and hurdles to overcome for developing efficacious vaccines against this dangerous pathogen.
在全球范围内,SARS-CoV-2被世界卫生组织(WHO)认定为大流行性病毒感染。在免疫反应方面,对病毒的认识非常有限,主要是先天免疫和适应性免疫反应。SARS-COV-2会导致严重的呼吸道疾病,有时会导致死亡。患者的身体有能力产生免疫来治愈患者,更重要的是,针对SARS-COV-2的体液免疫和细胞免疫都已经研究出来。与SARS-COV和MESR等其他以前的疾病一样,针对病毒感染有不同的免疫反应。科学家们以在康复患者身上检测到的免疫反应为基础,开始开发疫苗。此外,研究人员和药理学公司在开发疫苗时采用了不同的策略,包括减毒或灭活病毒、刺突蛋白的RNA和表达病毒特定蛋白质的载体。在感染或康复患者血清中检测到的抗SARS-COV-2的常见抗体是免疫球蛋白G (IgG)和免疫球蛋白M (IgM)。COVID-19患者经免疫球蛋白(IgG)滴度检测后的血清可用于治疗疾病或预防SARS-COV-2感染。本研究介绍了目前针对新出现的SARS-COV-2的免疫学方法和疫苗接种策略的最新情况,并讨论了开发针对这种危险病原体的有效疫苗需要克服的挑战和障碍。
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Kurdistan Journal of Applied Research
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