Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479825
Mehmet Özçelik, H. Ş. Bilge
Microscopic analysis of images in the health care at the cellular level is one of the important methods for analysis and final diagnosis. In the diagnosis of blood diseases, although high technology systems provide very important information, for a definitive diagnosis microscopic smear examinations are needed. Microscopic examination is a time-consuming task for doctors. Therefore, in this study a basic system has been developed that may speed up the eye examination. In future, further development of this system may be an alternative to visual examination. From the basic blood cells (leukocyte, erythrocyte, platelet), we only focused on the locations of white blood cells in the image. In the development process of this system real blood smear images has been used. In this study iterative algorithms are not used instead of this, logical and morphological processes have been used. This allows faster operation of the system.
{"title":"Finding leukocyte region in microscopic images","authors":"Mehmet Özçelik, H. Ş. Bilge","doi":"10.1109/BIYOMUT.2010.5479825","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479825","url":null,"abstract":"Microscopic analysis of images in the health care at the cellular level is one of the important methods for analysis and final diagnosis. In the diagnosis of blood diseases, although high technology systems provide very important information, for a definitive diagnosis microscopic smear examinations are needed. Microscopic examination is a time-consuming task for doctors. Therefore, in this study a basic system has been developed that may speed up the eye examination. In future, further development of this system may be an alternative to visual examination. From the basic blood cells (leukocyte, erythrocyte, platelet), we only focused on the locations of white blood cells in the image. In the development process of this system real blood smear images has been used. In this study iterative algorithms are not used instead of this, logical and morphological processes have been used. This allows faster operation of the system.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124560261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479836
Mehmet Akif Özçoban, F. Latifoğlu, A. Ülgen, M. H. Asyali
Bioelectric impedance analysis (BIA) is a widely technique in determining body composition. In this method, two electrodes are placed at suitable points on the body and alternating current at different frequencies are passed through those points. Then, the voltage difference between the two points is measured and corresponding bioelectric impedance is calculated. In this study, BIA measurement calculated with dielectric permeability technique. This method differs from the conventional BIA in that, the measurement is totally noninvasive. In future studies, we will apply the proposed method in determining the amount of total body water and weight ratio of dry body mass for hemodialysis patients.
{"title":"Monitoring the body water exchange using dielectric permeability method","authors":"Mehmet Akif Özçoban, F. Latifoğlu, A. Ülgen, M. H. Asyali","doi":"10.1109/BIYOMUT.2010.5479836","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479836","url":null,"abstract":"Bioelectric impedance analysis (BIA) is a widely technique in determining body composition. In this method, two electrodes are placed at suitable points on the body and alternating current at different frequencies are passed through those points. Then, the voltage difference between the two points is measured and corresponding bioelectric impedance is calculated. In this study, BIA measurement calculated with dielectric permeability technique. This method differs from the conventional BIA in that, the measurement is totally noninvasive. In future studies, we will apply the proposed method in determining the amount of total body water and weight ratio of dry body mass for hemodialysis patients.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124793833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479749
C. Isikli, T. Endogan, A. Kiziltay, V. Hasırcı, N. Hasirci
Hard tissue engineering has emerged to compensate for the losses in the properties of damaged bones by using scaffolds and cells. In this study, natural polymers chitosan and gelatin were used as scaffold materials because of their great resemblance to extracellular matrix elements. To enhance the mechanical properties and osteoconductivity of structures hydroxyapatite was added. This study is about the characterization of physico-chemical properties and cell behavior on scaffolds to optimize chitosan-gelatin ratio and aims to assess the effects of hydroxyapatite addition into polymeric matrix. According to thermal test results, decomposition temperatures decreased with non-sintered hydroxyapatite (nsHA) addition. Mechanical test results of composite structures were similar to that of cortical bone. Chitosan-gelatin films prepared with same amount of polymers showed the highest swelling degree. While nsHA added pure chitoan films showed higher cell number with respect to chitosan films; on the contrry, chitosan-gelatin polymeric blends indicated an opposite trend after nsHA addition.
{"title":"Preparation and characterization of natural polymer-based composite films for hard tissue engineering approaches","authors":"C. Isikli, T. Endogan, A. Kiziltay, V. Hasırcı, N. Hasirci","doi":"10.1109/BIYOMUT.2010.5479749","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479749","url":null,"abstract":"Hard tissue engineering has emerged to compensate for the losses in the properties of damaged bones by using scaffolds and cells. In this study, natural polymers chitosan and gelatin were used as scaffold materials because of their great resemblance to extracellular matrix elements. To enhance the mechanical properties and osteoconductivity of structures hydroxyapatite was added. This study is about the characterization of physico-chemical properties and cell behavior on scaffolds to optimize chitosan-gelatin ratio and aims to assess the effects of hydroxyapatite addition into polymeric matrix. According to thermal test results, decomposition temperatures decreased with non-sintered hydroxyapatite (nsHA) addition. Mechanical test results of composite structures were similar to that of cortical bone. Chitosan-gelatin films prepared with same amount of polymers showed the highest swelling degree. While nsHA added pure chitoan films showed higher cell number with respect to chitosan films; on the contrry, chitosan-gelatin polymeric blends indicated an opposite trend after nsHA addition.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130878056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479831
H. Olgar, M. Bilsel
(VPGXG)n polypeptides known as elastin-like polypeptides with different biological, biomechanical, biochemical and biophysical properties stand out suitable structures appropriate for production of several biomaterials, in the first instance, tissue, microtube and nanotube in tissue engineering. Therefore, understanding the structural properties of such peptides comes into prominence. For this purpose, structural properties of elastin-like polypeptides have been investigated by computer simulation methods in our study. Our simulations have been carried out by multicanonical algorithm having a wide range of application area from solid state to biophysics, the most powerful algorithm in generalized ensemble family. By taking n=1 and changing aminoacid X, hydrophobicity scale has been established in the forepart of our study, afterwards the effect on structural transition temperature has been determined in a solvent (SCH2) and vacuum. In the second part, choosing VPGVG, the most repeating pentapeptide sequence in elastin-like proteins, and taking n=1, 2, 3, 4, change in structural transition temperature and secondary structure formation caused by the transition from smaller molecule to larger one have been determined.
{"title":"Simulations of elastin like proteins","authors":"H. Olgar, M. Bilsel","doi":"10.1109/BIYOMUT.2010.5479831","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479831","url":null,"abstract":"(VPGXG)n polypeptides known as elastin-like polypeptides with different biological, biomechanical, biochemical and biophysical properties stand out suitable structures appropriate for production of several biomaterials, in the first instance, tissue, microtube and nanotube in tissue engineering. Therefore, understanding the structural properties of such peptides comes into prominence. For this purpose, structural properties of elastin-like polypeptides have been investigated by computer simulation methods in our study. Our simulations have been carried out by multicanonical algorithm having a wide range of application area from solid state to biophysics, the most powerful algorithm in generalized ensemble family. By taking n=1 and changing aminoacid X, hydrophobicity scale has been established in the forepart of our study, afterwards the effect on structural transition temperature has been determined in a solvent (SCH2) and vacuum. In the second part, choosing VPGVG, the most repeating pentapeptide sequence in elastin-like proteins, and taking n=1, 2, 3, 4, change in structural transition temperature and secondary structure formation caused by the transition from smaller molecule to larger one have been determined.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"94 8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128692714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479761
S. Bilgin, O. H. Colak, Gürkan Bilgin, Ozhan Ozkan, S. Yıldız, E. Koklukaya, O. Elmas, S. Comlekci, H. Koyuncuoglu, S. Akkus
Fibromyalgia syndrome which is appeared in the form of common pain in women is a musculoskeletal disorder. Heart rate variability (HRV) is a signal as measured time between each successive QRS time obtained from ECG signal. HRV parameters are associated with autonomic nervous system in literature. FMS affects patient's psychology. Consequently some psychological tests are applied to patients for evaluation of psychological effects. Beck Anxiety Inventory (BAI) Test being applied as writing and speaking is a test consisting of 21 questions. In the study, HRV signals obtained from FMS patients and control group are decomposed into wavelet packets using Wavelet Packet Transform (WPT) and frequency bands which related to autonomic nervous system are included to study. Wavelet Packets within these frequency bands are applied to inputs of multilayer perceptron artificial neural networks (MLPNN). BAI psychological test scores are included as target values for MLPNN and each input is trained and tested as relating to target values. According to obtained accuracy values, the packets within Very Low Frequency (VLF) band has minimum accuracy values, however the packets within Low Frequency + High Frequency (LF+HF) has the best accuracy values. This study is targeted on presenting a solution for clinical studies which are evaluated using psychological test scores by physiological support.
纤维肌痛综合征是一种肌肉骨骼疾病，以女性常见疼痛的形式出现。心率变异性(HRV)是由心电信号获得的每个连续QRS时间之间的测量时间信号。文献中认为HRV参数与自主神经系统有关。FMS会影响患者的心理。因此，对患者进行一些心理测试来评估心理影响。贝克焦虑量表(BAI)测试应用于写作和口语，是一个由21个问题组成的测试。本研究采用小波包变换(wavelet Packet Transform, WPT)对FMS患者和对照组的HRV信号进行小波包分解，选取与自主神经系统相关的频段进行研究。将这些频带内的小波包应用于多层感知器人工神经网络(MLPNN)的输入。BAI心理测试分数作为MLPNN的目标值，每个输入都根据目标值进行训练和测试。根据得到的精度值，VLF (Very Low Frequency)频段内的报文精度值最小，LF+HF (Low Frequency + High Frequency)频段内的报文精度值最好。本研究旨在为临床研究提供一个解决方案，这些临床研究是通过生理支持来评估心理测试分数的。
{"title":"Correlation of BAI psychological test scores with heart rate variability using wavelet packet transform and artificial neural networks in fibromyalgia syndrome","authors":"S. Bilgin, O. H. Colak, Gürkan Bilgin, Ozhan Ozkan, S. Yıldız, E. Koklukaya, O. Elmas, S. Comlekci, H. Koyuncuoglu, S. Akkus","doi":"10.1109/BIYOMUT.2010.5479761","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479761","url":null,"abstract":"Fibromyalgia syndrome which is appeared in the form of common pain in women is a musculoskeletal disorder. Heart rate variability (HRV) is a signal as measured time between each successive QRS time obtained from ECG signal. HRV parameters are associated with autonomic nervous system in literature. FMS affects patient's psychology. Consequently some psychological tests are applied to patients for evaluation of psychological effects. Beck Anxiety Inventory (BAI) Test being applied as writing and speaking is a test consisting of 21 questions. In the study, HRV signals obtained from FMS patients and control group are decomposed into wavelet packets using Wavelet Packet Transform (WPT) and frequency bands which related to autonomic nervous system are included to study. Wavelet Packets within these frequency bands are applied to inputs of multilayer perceptron artificial neural networks (MLPNN). BAI psychological test scores are included as target values for MLPNN and each input is trained and tested as relating to target values. According to obtained accuracy values, the packets within Very Low Frequency (VLF) band has minimum accuracy values, however the packets within Low Frequency + High Frequency (LF+HF) has the best accuracy values. This study is targeted on presenting a solution for clinical studies which are evaluated using psychological test scores by physiological support.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124163223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479754
F. Susam, F. Ates, Can A. Yücesoy
In this study, the distribution of glycogen in fiber direction is examined histologically in rat EDL muscle in order to investigate the intramuscular mechanism of botox. The muscle was not exposed to any physical activity or electrical stimulation; it was directly subjected to histological study. The longitudinal sections obtained from the paraffin-embedded tissue was stained by Periodic Acid and Schiff (PAS) solutions, afterwards hematoxylin Mayer's and bluing agent was added. Under the influence of PAS, the areas containing glycogen was observed as blue and the nuclei was dark blue. Furthermore, fiber directions were also determined with the contribution of the second step. As a result of these studies it was observed that glycogen was distributed among the whole muscle in the fiber direction. Utilizing the obtained findings, botox injected muscle will be stained with PAS and paralyzed muscle fiber patterns will be determined. The mechanical effects of botox will be examined intramuscularly and the first results will be presented in the congress.
{"title":"Demonstration of fiber direction glycogen in the rat EDL muscle with longitudinal sections: Histological assessment","authors":"F. Susam, F. Ates, Can A. Yücesoy","doi":"10.1109/BIYOMUT.2010.5479754","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479754","url":null,"abstract":"In this study, the distribution of glycogen in fiber direction is examined histologically in rat EDL muscle in order to investigate the intramuscular mechanism of botox. The muscle was not exposed to any physical activity or electrical stimulation; it was directly subjected to histological study. The longitudinal sections obtained from the paraffin-embedded tissue was stained by Periodic Acid and Schiff (PAS) solutions, afterwards hematoxylin Mayer's and bluing agent was added. Under the influence of PAS, the areas containing glycogen was observed as blue and the nuclei was dark blue. Furthermore, fiber directions were also determined with the contribution of the second step. As a result of these studies it was observed that glycogen was distributed among the whole muscle in the fiber direction. Utilizing the obtained findings, botox injected muscle will be stained with PAS and paralyzed muscle fiber patterns will be determined. The mechanical effects of botox will be examined intramuscularly and the first results will be presented in the congress.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124359951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479780
F. S. Utku, Eren Seckin, G. Goller, C. Tamerler, M. Urgen
Titanium and its alloys are used in dental and orthopaedic applications. Chemical and physical properties of implant surfaces are important determinants of implant stability and osteointegration. In this study, pure titanium, anodized titania and ordered titanium dioxide nanotubular plates were coated with calcium phosphate using a modified SBF solution and pulsed electrodeposition process at 80°C, with a current density of -10mA/cm2. Calcium phosphate deposition was characterized using XRD, FTIR and FE-SEM. Although carbonated hydroxyapatite and calcium deficient hydroxyapatite phases were deposited on all surface types, the deposition on nanoporous titania displayed significant differences from those on anodized titania and flat titanium. Our results indicated that ordered titanium oxide nanotubes providing a larger surface area for hydroxide ion generation, enabled deposition of carbonated hydroxyapatite phases, which flat and anodized titania plates do not to the same extent under same reaction conditions.
{"title":"Effect of titanium surface properties on electrochemically induced biomineralization","authors":"F. S. Utku, Eren Seckin, G. Goller, C. Tamerler, M. Urgen","doi":"10.1109/BIYOMUT.2010.5479780","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479780","url":null,"abstract":"Titanium and its alloys are used in dental and orthopaedic applications. Chemical and physical properties of implant surfaces are important determinants of implant stability and osteointegration. In this study, pure titanium, anodized titania and ordered titanium dioxide nanotubular plates were coated with calcium phosphate using a modified SBF solution and pulsed electrodeposition process at 80°C, with a current density of -10mA/cm2. Calcium phosphate deposition was characterized using XRD, FTIR and FE-SEM. Although carbonated hydroxyapatite and calcium deficient hydroxyapatite phases were deposited on all surface types, the deposition on nanoporous titania displayed significant differences from those on anodized titania and flat titanium. Our results indicated that ordered titanium oxide nanotubes providing a larger surface area for hydroxide ion generation, enabled deposition of carbonated hydroxyapatite phases, which flat and anodized titania plates do not to the same extent under same reaction conditions.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128080881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479864
S. Akdemir, S. Kara, V. Bilgiç
Here, respiratory signals were recorded from schizophrenia patients and healthy controls. The purpose of this study is to compare the respiratory effects as respiration rate and depth of different auditory stimuli in these two groups. Signals derived from a strain gauge attached to the chest were recorded for 8 min. which includes silence, Classical Turkish Music (CTM) and acoustic white noise stimulation periods. Although CTM, evoked an increase in respiration rate and a decrease in respiration depth in the control group, only a respiration rate acceleration was found in the patient group. Results showed that in order to evaluate the responses of the autonomic system and to clarify the effects of CTM, different physiological measurements taken into account. As a result of this, the emotional changes could be evaluated quantitatively.
{"title":"The investigation of respiratory differences during different auditory stimuli in schizophrenia patients","authors":"S. Akdemir, S. Kara, V. Bilgiç","doi":"10.1109/BIYOMUT.2010.5479864","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479864","url":null,"abstract":"Here, respiratory signals were recorded from schizophrenia patients and healthy controls. The purpose of this study is to compare the respiratory effects as respiration rate and depth of different auditory stimuli in these two groups. Signals derived from a strain gauge attached to the chest were recorded for 8 min. which includes silence, Classical Turkish Music (CTM) and acoustic white noise stimulation periods. Although CTM, evoked an increase in respiration rate and a decrease in respiration depth in the control group, only a respiration rate acceleration was found in the patient group. Results showed that in order to evaluate the responses of the autonomic system and to clarify the effects of CTM, different physiological measurements taken into account. As a result of this, the emotional changes could be evaluated quantitatively.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134415892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479763
B. Ergen, M. Baykara
Content based image retrieval systems are used widespread for general purpose image archiving, and the developments are still continued it. But it is not widely used for archiving medical images. In presented, it is examined the retrieval efficiency rate of statistical spatial methods used for feature extraction in general purpose images. The investigated algorithms depend on GLCM and GLRLM accepted as spatial methods. The results obtained in this study shows that queries based on statistics obtained from GLCM are more satisfier.
{"title":"Feature extraction of using statistical spatial methods for content based medical image retrieval","authors":"B. Ergen, M. Baykara","doi":"10.1109/BIYOMUT.2010.5479763","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479763","url":null,"abstract":"Content based image retrieval systems are used widespread for general purpose image archiving, and the developments are still continued it. But it is not widely used for archiving medical images. In presented, it is examined the retrieval efficiency rate of statistical spatial methods used for feature extraction in general purpose images. The investigated algorithms depend on GLCM and GLRLM accepted as spatial methods. The results obtained in this study shows that queries based on statistics obtained from GLCM are more satisfier.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133040996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479813
O. Arikan, Burak Güçlü, P. Huijing, Can A. Yücesoy
It has been shown that non-tendinous structures play a major role in force transmission: epimuscular myofascial force transmission. Such force transmission was shown to cause substantial strain distributions along muscle fibers indicating serial heterogeneity of sarcomere lengths. Recent studies showed evidence on sizable inter-antagonistic epimuscular myofascial force transmission. It is hypothesized in this study that epimuscular myofascial force transmission can play a role in afferent signals generated in muscle sensory organs. The goal of our present study was to test this hypothesis by measuring the afferent firing rates of antagonistic muscles of the lower leg. Gastrocnemius muscle of the frog (Rana ridibunda) was given 1-5 mm of ramp-and-hold stretch via a pulley mechanism connected to its distal tendon. Keeping the ankle and knee angles fixed (at 100° and 120°, respectively), sensory unit recordings were taken from both tibial and peroneal branches of sciatic nerve simultaneously: afferent signals generated from both the lengthened gastrocnemius muscle and the restrained antagonistic muscles were recorded. Remarkably, imposing passive stretch resulted in a significant increase in the firing rates of the units of not only the lengthened muscle, but also of the restrained antagonists (p<;0,05 n=12). This novel finding suggests that due to epimuscular myofascial force transmission, stretching of the target muscle causes local length changes sensed by the sensory organs within the fibers of the antagonistic muscles, despite being restrained. Our results therefore provide a preliminary support to our hypothesis and are likely to have major implications on our understanding of the functioning of muscular mechanoreceptors.
{"title":"Experimental assessment of the effects of epimuscular myofascial force transmission in the sensory level","authors":"O. Arikan, Burak Güçlü, P. Huijing, Can A. Yücesoy","doi":"10.1109/BIYOMUT.2010.5479813","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479813","url":null,"abstract":"It has been shown that non-tendinous structures play a major role in force transmission: epimuscular myofascial force transmission. Such force transmission was shown to cause substantial strain distributions along muscle fibers indicating serial heterogeneity of sarcomere lengths. Recent studies showed evidence on sizable inter-antagonistic epimuscular myofascial force transmission. It is hypothesized in this study that epimuscular myofascial force transmission can play a role in afferent signals generated in muscle sensory organs. The goal of our present study was to test this hypothesis by measuring the afferent firing rates of antagonistic muscles of the lower leg. Gastrocnemius muscle of the frog (Rana ridibunda) was given 1-5 mm of ramp-and-hold stretch via a pulley mechanism connected to its distal tendon. Keeping the ankle and knee angles fixed (at 100° and 120°, respectively), sensory unit recordings were taken from both tibial and peroneal branches of sciatic nerve simultaneously: afferent signals generated from both the lengthened gastrocnemius muscle and the restrained antagonistic muscles were recorded. Remarkably, imposing passive stretch resulted in a significant increase in the firing rates of the units of not only the lengthened muscle, but also of the restrained antagonists (p<;0,05 n=12). This novel finding suggests that due to epimuscular myofascial force transmission, stretching of the target muscle causes local length changes sensed by the sensory organs within the fibers of the antagonistic muscles, despite being restrained. Our results therefore provide a preliminary support to our hypothesis and are likely to have major implications on our understanding of the functioning of muscular mechanoreceptors.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133084581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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