Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479800
Güray Gürkan, A. Uslu, Bora Cebeci, E. Erdogan, Itir Kasikci, T. O. Seyhan, A. Akan, T. Demiralp
In this study, we present the spatial and temporal evolution of EEG signal spectrum under anaesthesia. Studied features include SEF-90, α-β power ratios, spectral entropy that are known to be used in commercially available depth of anaesthesia monitors. As an additional and comparing feature, we also present Higuchi fractal dimension that is used for analysis of non-linear systems. By means of spatial analysis, we verified the shift of occipitally dominant alpha activity to frontal regions and demonstrated corresponding topographic plots.
{"title":"Topographic and temporal spectral analysis of EEG signals during anaesthesia","authors":"Güray Gürkan, A. Uslu, Bora Cebeci, E. Erdogan, Itir Kasikci, T. O. Seyhan, A. Akan, T. Demiralp","doi":"10.1109/BIYOMUT.2010.5479800","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479800","url":null,"abstract":"In this study, we present the spatial and temporal evolution of EEG signal spectrum under anaesthesia. Studied features include SEF-90, α-β power ratios, spectral entropy that are known to be used in commercially available depth of anaesthesia monitors. As an additional and comparing feature, we also present Higuchi fractal dimension that is used for analysis of non-linear systems. By means of spatial analysis, we verified the shift of occipitally dominant alpha activity to frontal regions and demonstrated corresponding topographic plots.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116166260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479761
S. Bilgin, O. H. Colak, Gürkan Bilgin, Ozhan Ozkan, S. Yıldız, E. Koklukaya, O. Elmas, S. Comlekci, H. Koyuncuoglu, S. Akkus
Fibromyalgia syndrome which is appeared in the form of common pain in women is a musculoskeletal disorder. Heart rate variability (HRV) is a signal as measured time between each successive QRS time obtained from ECG signal. HRV parameters are associated with autonomic nervous system in literature. FMS affects patient's psychology. Consequently some psychological tests are applied to patients for evaluation of psychological effects. Beck Anxiety Inventory (BAI) Test being applied as writing and speaking is a test consisting of 21 questions. In the study, HRV signals obtained from FMS patients and control group are decomposed into wavelet packets using Wavelet Packet Transform (WPT) and frequency bands which related to autonomic nervous system are included to study. Wavelet Packets within these frequency bands are applied to inputs of multilayer perceptron artificial neural networks (MLPNN). BAI psychological test scores are included as target values for MLPNN and each input is trained and tested as relating to target values. According to obtained accuracy values, the packets within Very Low Frequency (VLF) band has minimum accuracy values, however the packets within Low Frequency + High Frequency (LF+HF) has the best accuracy values. This study is targeted on presenting a solution for clinical studies which are evaluated using psychological test scores by physiological support.
纤维肌痛综合征是一种肌肉骨骼疾病，以女性常见疼痛的形式出现。心率变异性(HRV)是由心电信号获得的每个连续QRS时间之间的测量时间信号。文献中认为HRV参数与自主神经系统有关。FMS会影响患者的心理。因此，对患者进行一些心理测试来评估心理影响。贝克焦虑量表(BAI)测试应用于写作和口语，是一个由21个问题组成的测试。本研究采用小波包变换(wavelet Packet Transform, WPT)对FMS患者和对照组的HRV信号进行小波包分解，选取与自主神经系统相关的频段进行研究。将这些频带内的小波包应用于多层感知器人工神经网络(MLPNN)的输入。BAI心理测试分数作为MLPNN的目标值，每个输入都根据目标值进行训练和测试。根据得到的精度值，VLF (Very Low Frequency)频段内的报文精度值最小，LF+HF (Low Frequency + High Frequency)频段内的报文精度值最好。本研究旨在为临床研究提供一个解决方案，这些临床研究是通过生理支持来评估心理测试分数的。
{"title":"Correlation of BAI psychological test scores with heart rate variability using wavelet packet transform and artificial neural networks in fibromyalgia syndrome","authors":"S. Bilgin, O. H. Colak, Gürkan Bilgin, Ozhan Ozkan, S. Yıldız, E. Koklukaya, O. Elmas, S. Comlekci, H. Koyuncuoglu, S. Akkus","doi":"10.1109/BIYOMUT.2010.5479761","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479761","url":null,"abstract":"Fibromyalgia syndrome which is appeared in the form of common pain in women is a musculoskeletal disorder. Heart rate variability (HRV) is a signal as measured time between each successive QRS time obtained from ECG signal. HRV parameters are associated with autonomic nervous system in literature. FMS affects patient's psychology. Consequently some psychological tests are applied to patients for evaluation of psychological effects. Beck Anxiety Inventory (BAI) Test being applied as writing and speaking is a test consisting of 21 questions. In the study, HRV signals obtained from FMS patients and control group are decomposed into wavelet packets using Wavelet Packet Transform (WPT) and frequency bands which related to autonomic nervous system are included to study. Wavelet Packets within these frequency bands are applied to inputs of multilayer perceptron artificial neural networks (MLPNN). BAI psychological test scores are included as target values for MLPNN and each input is trained and tested as relating to target values. According to obtained accuracy values, the packets within Very Low Frequency (VLF) band has minimum accuracy values, however the packets within Low Frequency + High Frequency (LF+HF) has the best accuracy values. This study is targeted on presenting a solution for clinical studies which are evaluated using psychological test scores by physiological support.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124163223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479754
F. Susam, F. Ates, Can A. Yücesoy
In this study, the distribution of glycogen in fiber direction is examined histologically in rat EDL muscle in order to investigate the intramuscular mechanism of botox. The muscle was not exposed to any physical activity or electrical stimulation; it was directly subjected to histological study. The longitudinal sections obtained from the paraffin-embedded tissue was stained by Periodic Acid and Schiff (PAS) solutions, afterwards hematoxylin Mayer's and bluing agent was added. Under the influence of PAS, the areas containing glycogen was observed as blue and the nuclei was dark blue. Furthermore, fiber directions were also determined with the contribution of the second step. As a result of these studies it was observed that glycogen was distributed among the whole muscle in the fiber direction. Utilizing the obtained findings, botox injected muscle will be stained with PAS and paralyzed muscle fiber patterns will be determined. The mechanical effects of botox will be examined intramuscularly and the first results will be presented in the congress.
{"title":"Demonstration of fiber direction glycogen in the rat EDL muscle with longitudinal sections: Histological assessment","authors":"F. Susam, F. Ates, Can A. Yücesoy","doi":"10.1109/BIYOMUT.2010.5479754","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479754","url":null,"abstract":"In this study, the distribution of glycogen in fiber direction is examined histologically in rat EDL muscle in order to investigate the intramuscular mechanism of botox. The muscle was not exposed to any physical activity or electrical stimulation; it was directly subjected to histological study. The longitudinal sections obtained from the paraffin-embedded tissue was stained by Periodic Acid and Schiff (PAS) solutions, afterwards hematoxylin Mayer's and bluing agent was added. Under the influence of PAS, the areas containing glycogen was observed as blue and the nuclei was dark blue. Furthermore, fiber directions were also determined with the contribution of the second step. As a result of these studies it was observed that glycogen was distributed among the whole muscle in the fiber direction. Utilizing the obtained findings, botox injected muscle will be stained with PAS and paralyzed muscle fiber patterns will be determined. The mechanical effects of botox will be examined intramuscularly and the first results will be presented in the congress.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124359951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479842
Umut Orhan, M. Hekim, M. Özer
Electroencephalogram (EEG) recording systems have been frequently used as the sources of information in diagnosis of epilepsy by several researchers. In this study, rearranged EEG signals were classified by Multilayer Perceptron Neural Network (MLPNN) model. Used data consists of five groups (A, B, C, D, and E) each containing 100 EEG segments. In this study, center points with equal interval were selected on amplitude axis of each EEG segment. EEG signals were rearranged by way of that each amplitude value was shifted to the center point closest to itself. Equal width discretization (EWD) method was used for rearrangement process. Wavelet coefficients of each segment of EEG signals were computed by using discrete wavelet transform (DWT). The mean, the standard deviation and the entropy of these coefficients was used as the inputs of MLPNN model. The model was protected from the overfitting by cross validation. Two different classification experiments were implemented by the same MLPNN model: 1) the classification of healthy volunteers, epilepsy patients during seizure and epilepsy patients during a seizure-free interval, 2) the classification of epilepsy patients during seizure and seizure-free interval. MLPNN model classified EEG signals with the accuracy of 99.60% in first experiment and 100% in second experiment. It is observed that MLPNN classification of EEG signals after rearrangement in amplitude axis provides better results.
{"title":"Discretization approach to EEG signal classification using Multilayer Perceptron Neural Network model","authors":"Umut Orhan, M. Hekim, M. Özer","doi":"10.1109/BIYOMUT.2010.5479842","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479842","url":null,"abstract":"Electroencephalogram (EEG) recording systems have been frequently used as the sources of information in diagnosis of epilepsy by several researchers. In this study, rearranged EEG signals were classified by Multilayer Perceptron Neural Network (MLPNN) model. Used data consists of five groups (A, B, C, D, and E) each containing 100 EEG segments. In this study, center points with equal interval were selected on amplitude axis of each EEG segment. EEG signals were rearranged by way of that each amplitude value was shifted to the center point closest to itself. Equal width discretization (EWD) method was used for rearrangement process. Wavelet coefficients of each segment of EEG signals were computed by using discrete wavelet transform (DWT). The mean, the standard deviation and the entropy of these coefficients was used as the inputs of MLPNN model. The model was protected from the overfitting by cross validation. Two different classification experiments were implemented by the same MLPNN model: 1) the classification of healthy volunteers, epilepsy patients during seizure and epilepsy patients during a seizure-free interval, 2) the classification of epilepsy patients during seizure and seizure-free interval. MLPNN model classified EEG signals with the accuracy of 99.60% in first experiment and 100% in second experiment. It is observed that MLPNN classification of EEG signals after rearrangement in amplitude axis provides better results.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129440467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479749
C. Isikli, T. Endogan, A. Kiziltay, V. Hasırcı, N. Hasirci
Hard tissue engineering has emerged to compensate for the losses in the properties of damaged bones by using scaffolds and cells. In this study, natural polymers chitosan and gelatin were used as scaffold materials because of their great resemblance to extracellular matrix elements. To enhance the mechanical properties and osteoconductivity of structures hydroxyapatite was added. This study is about the characterization of physico-chemical properties and cell behavior on scaffolds to optimize chitosan-gelatin ratio and aims to assess the effects of hydroxyapatite addition into polymeric matrix. According to thermal test results, decomposition temperatures decreased with non-sintered hydroxyapatite (nsHA) addition. Mechanical test results of composite structures were similar to that of cortical bone. Chitosan-gelatin films prepared with same amount of polymers showed the highest swelling degree. While nsHA added pure chitoan films showed higher cell number with respect to chitosan films; on the contrry, chitosan-gelatin polymeric blends indicated an opposite trend after nsHA addition.
{"title":"Preparation and characterization of natural polymer-based composite films for hard tissue engineering approaches","authors":"C. Isikli, T. Endogan, A. Kiziltay, V. Hasırcı, N. Hasirci","doi":"10.1109/BIYOMUT.2010.5479749","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479749","url":null,"abstract":"Hard tissue engineering has emerged to compensate for the losses in the properties of damaged bones by using scaffolds and cells. In this study, natural polymers chitosan and gelatin were used as scaffold materials because of their great resemblance to extracellular matrix elements. To enhance the mechanical properties and osteoconductivity of structures hydroxyapatite was added. This study is about the characterization of physico-chemical properties and cell behavior on scaffolds to optimize chitosan-gelatin ratio and aims to assess the effects of hydroxyapatite addition into polymeric matrix. According to thermal test results, decomposition temperatures decreased with non-sintered hydroxyapatite (nsHA) addition. Mechanical test results of composite structures were similar to that of cortical bone. Chitosan-gelatin films prepared with same amount of polymers showed the highest swelling degree. While nsHA added pure chitoan films showed higher cell number with respect to chitosan films; on the contrry, chitosan-gelatin polymeric blends indicated an opposite trend after nsHA addition.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130878056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479860
Yasin Güven, D. Barkana
Recent research in orthopedic surgeries indicates that computerassisted robotic systems have shown that robots may improve the precision and accuracy of the surgery which in turn leads to better long-term outcomes. An orthopedic robotic system called OrthoRoby and an intelligent control architecture that will be used in bone cutting operations were developed. In this paper, a medical user interface was developed and integrated into the OrthoRoby system. Medical user interface used Computed Tomography (CT) images of the patients' bone.
{"title":"Medical user interface for orthopedical surgical robotic system","authors":"Yasin Güven, D. Barkana","doi":"10.1109/BIYOMUT.2010.5479860","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479860","url":null,"abstract":"Recent research in orthopedic surgeries indicates that computerassisted robotic systems have shown that robots may improve the precision and accuracy of the surgery which in turn leads to better long-term outcomes. An orthopedic robotic system called OrthoRoby and an intelligent control architecture that will be used in bone cutting operations were developed. In this paper, a medical user interface was developed and integrated into the OrthoRoby system. Medical user interface used Computed Tomography (CT) images of the patients' bone.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130276453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479836
Mehmet Akif Özçoban, F. Latifoğlu, A. Ülgen, M. H. Asyali
Bioelectric impedance analysis (BIA) is a widely technique in determining body composition. In this method, two electrodes are placed at suitable points on the body and alternating current at different frequencies are passed through those points. Then, the voltage difference between the two points is measured and corresponding bioelectric impedance is calculated. In this study, BIA measurement calculated with dielectric permeability technique. This method differs from the conventional BIA in that, the measurement is totally noninvasive. In future studies, we will apply the proposed method in determining the amount of total body water and weight ratio of dry body mass for hemodialysis patients.
{"title":"Monitoring the body water exchange using dielectric permeability method","authors":"Mehmet Akif Özçoban, F. Latifoğlu, A. Ülgen, M. H. Asyali","doi":"10.1109/BIYOMUT.2010.5479836","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479836","url":null,"abstract":"Bioelectric impedance analysis (BIA) is a widely technique in determining body composition. In this method, two electrodes are placed at suitable points on the body and alternating current at different frequencies are passed through those points. Then, the voltage difference between the two points is measured and corresponding bioelectric impedance is calculated. In this study, BIA measurement calculated with dielectric permeability technique. This method differs from the conventional BIA in that, the measurement is totally noninvasive. In future studies, we will apply the proposed method in determining the amount of total body water and weight ratio of dry body mass for hemodialysis patients.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124793833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479780
F. S. Utku, Eren Seckin, G. Goller, C. Tamerler, M. Urgen
Titanium and its alloys are used in dental and orthopaedic applications. Chemical and physical properties of implant surfaces are important determinants of implant stability and osteointegration. In this study, pure titanium, anodized titania and ordered titanium dioxide nanotubular plates were coated with calcium phosphate using a modified SBF solution and pulsed electrodeposition process at 80°C, with a current density of -10mA/cm2. Calcium phosphate deposition was characterized using XRD, FTIR and FE-SEM. Although carbonated hydroxyapatite and calcium deficient hydroxyapatite phases were deposited on all surface types, the deposition on nanoporous titania displayed significant differences from those on anodized titania and flat titanium. Our results indicated that ordered titanium oxide nanotubes providing a larger surface area for hydroxide ion generation, enabled deposition of carbonated hydroxyapatite phases, which flat and anodized titania plates do not to the same extent under same reaction conditions.
{"title":"Effect of titanium surface properties on electrochemically induced biomineralization","authors":"F. S. Utku, Eren Seckin, G. Goller, C. Tamerler, M. Urgen","doi":"10.1109/BIYOMUT.2010.5479780","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479780","url":null,"abstract":"Titanium and its alloys are used in dental and orthopaedic applications. Chemical and physical properties of implant surfaces are important determinants of implant stability and osteointegration. In this study, pure titanium, anodized titania and ordered titanium dioxide nanotubular plates were coated with calcium phosphate using a modified SBF solution and pulsed electrodeposition process at 80°C, with a current density of -10mA/cm2. Calcium phosphate deposition was characterized using XRD, FTIR and FE-SEM. Although carbonated hydroxyapatite and calcium deficient hydroxyapatite phases were deposited on all surface types, the deposition on nanoporous titania displayed significant differences from those on anodized titania and flat titanium. Our results indicated that ordered titanium oxide nanotubes providing a larger surface area for hydroxide ion generation, enabled deposition of carbonated hydroxyapatite phases, which flat and anodized titania plates do not to the same extent under same reaction conditions.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128080881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479831
H. Olgar, M. Bilsel
(VPGXG)n polypeptides known as elastin-like polypeptides with different biological, biomechanical, biochemical and biophysical properties stand out suitable structures appropriate for production of several biomaterials, in the first instance, tissue, microtube and nanotube in tissue engineering. Therefore, understanding the structural properties of such peptides comes into prominence. For this purpose, structural properties of elastin-like polypeptides have been investigated by computer simulation methods in our study. Our simulations have been carried out by multicanonical algorithm having a wide range of application area from solid state to biophysics, the most powerful algorithm in generalized ensemble family. By taking n=1 and changing aminoacid X, hydrophobicity scale has been established in the forepart of our study, afterwards the effect on structural transition temperature has been determined in a solvent (SCH2) and vacuum. In the second part, choosing VPGVG, the most repeating pentapeptide sequence in elastin-like proteins, and taking n=1, 2, 3, 4, change in structural transition temperature and secondary structure formation caused by the transition from smaller molecule to larger one have been determined.
{"title":"Simulations of elastin like proteins","authors":"H. Olgar, M. Bilsel","doi":"10.1109/BIYOMUT.2010.5479831","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479831","url":null,"abstract":"(VPGXG)n polypeptides known as elastin-like polypeptides with different biological, biomechanical, biochemical and biophysical properties stand out suitable structures appropriate for production of several biomaterials, in the first instance, tissue, microtube and nanotube in tissue engineering. Therefore, understanding the structural properties of such peptides comes into prominence. For this purpose, structural properties of elastin-like polypeptides have been investigated by computer simulation methods in our study. Our simulations have been carried out by multicanonical algorithm having a wide range of application area from solid state to biophysics, the most powerful algorithm in generalized ensemble family. By taking n=1 and changing aminoacid X, hydrophobicity scale has been established in the forepart of our study, afterwards the effect on structural transition temperature has been determined in a solvent (SCH2) and vacuum. In the second part, choosing VPGVG, the most repeating pentapeptide sequence in elastin-like proteins, and taking n=1, 2, 3, 4, change in structural transition temperature and secondary structure formation caused by the transition from smaller molecule to larger one have been determined.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"94 8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128692714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479777
G. Şengül, U. Baysal
In this study a fully automatic fotogrammetric system is designed to determine the EEG electrode positions in 3D. The proposed system uses a 1.3 MP web camera rotating over the subject's head. The camera is driven by a step motor. The camera takes photos in every 7.20 angles during the rotation. In order to realize full automation, electrodes are labeled by colored circular markers and an electrode identification algorithm is develeoped for full automation. The proposed method is tested by using a realistic head phantom carrying 25 electrodes. The positions of the test electrodes are also measured by a conventional 3-D digitizer. The measurements are repeated 3 times for repeatibility purposes. It is found that 3-d digitizer localizes the electrodes with an average error of 8.46 mm, 7.63 mm and 8.32 mm, while the proposed system localizes the electrodes with an average error of 1.76 mm, 1.42 mm and 1.53 mm.
{"title":"A fully automatic photogrammetric system design using a 1.3 MP web camera to determine EEG electrode positions","authors":"G. Şengül, U. Baysal","doi":"10.1109/BIYOMUT.2010.5479777","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479777","url":null,"abstract":"In this study a fully automatic fotogrammetric system is designed to determine the EEG electrode positions in 3D. The proposed system uses a 1.3 MP web camera rotating over the subject's head. The camera is driven by a step motor. The camera takes photos in every 7.20 angles during the rotation. In order to realize full automation, electrodes are labeled by colored circular markers and an electrode identification algorithm is develeoped for full automation. The proposed method is tested by using a realistic head phantom carrying 25 electrodes. The positions of the test electrodes are also measured by a conventional 3-D digitizer. The measurements are repeated 3 times for repeatibility purposes. It is found that 3-d digitizer localizes the electrodes with an average error of 8.46 mm, 7.63 mm and 8.32 mm, while the proposed system localizes the electrodes with an average error of 1.76 mm, 1.42 mm and 1.53 mm.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125770270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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