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2010 15th National Biomedical Engineering Meeting最新文献

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In vitro pulsatile flow waveform simulation and comparison using AC pump and proportional pneumatic valve 交流泵与比例气动阀体外脉动流量波形的仿真与比较
Pub Date : 2010-04-21 DOI: 10.1109/BIYOMUT.2010.5479796
Serdar Yilmaz, N. Arslan, O. Toker, H. Sedef
Patients, with renal failure, can be taken to the hemodialysis after fistula or graft surgery. In hemodialysis, blood is pumped with the help of the artificial kidney machine and the waste product from the blood is filtered and blood is returned to the patients after cleaning process. AV graft implantation is the creation of a polytetrafluoroethylene (PTFE) bridge a bridge between the arteries and veins. In this study simulation of the pulsatile flow signal in the AV graft and vein connection is aimed experimentally. Suitable for this purpose AC centrifugal pump, pump driver card, pneumatic valve, data acquisition card, flow meters and other equipments are used for close loop control mechanism in laboratory. Pulsatile waveforms obtained by AC centrifugal pump and pneumatic valve performance are compared to each other in close loop control. The results showed that AV graft signal can be modeled by AC centrifugal pump and pneumatic valve successfully. Current study could be a guide and motivation to the establishment of the different experimental systems in future.
肾功能衰竭的患者,可在瘘管或移植物手术后进行血液透析。在血液透析中,血液在人工肾机的帮助下被泵出,血液中的废物被过滤,血液经过清洁过程后返回给患者。AV移植物植入术是在动脉和静脉之间建立一个聚四氟乙烯(PTFE)桥。本研究旨在实验模拟心室移植物与静脉连接中的脉动血流信号。交流离心泵、泵驱动卡、气动阀、数据采集卡、流量计等设备用于实验室闭环控制机构。在闭环控制下,对交流离心泵和气动阀性能得到的脉动波形进行了比较。结果表明,利用交流离心泵和气动阀可以成功地对AV接枝信号进行建模。本文的研究对今后不同实验体系的建立具有一定的指导和激励作用。
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引用次数: 1
Detection of kidney stones from X-ray images 从x射线图像中检测肾结石
Pub Date : 2010-04-21 DOI: 10.1109/BIYOMUT.2010.5479868
Abidin Altintas, C. Unsalan, A. U. Keskin, F. Yencilek
Extracorporeal Shock Wave Lithotrispy (ESWL) is a procedure based on sound waves to crash kidney stones on the focus. The sound waves are sent to the body of patient when the kidney stone is not even on the focus. When the stone is not on the focus, the sound waves can damage the soft tissue of the kidney. This damage can be prevented by a feedback mechanism that determines the place of kidney stones depending on the images taken from ESWL device. In this study, an automated system is developed to detect kidney stones from X ray images.
体外冲击波碎石术(ESWL)是一种基于声波在焦点上撞击肾结石的手术。声波被传送到病人的身体时,肾结石甚至没有在焦点上。当结石不在焦点上时,声波会损害肾脏的软组织。这种损害可以通过一个反馈机制来预防,该机制根据ESWL设备拍摄的图像来确定肾结石的位置。在这项研究中,开发了一种自动化系统,可以从X射线图像中检测肾结石。
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引用次数: 2
Designing 3 language talkative system of heart beater 设计三种语言的心跳器对话系统
Pub Date : 2010-04-21 DOI: 10.1109/BIYOMUT.2010.5479812
Bulent Perktas, M. Aksahin
Today, the increasing contribution of biomedical devices is well known for diagnosis and treatment of common diseases. The heart rate is an important parameter among this diagnosis. The heart rate is the total number performed heart beats in a minute. In this study, the heart rate is detected proportionally to the intensity oxyhemoglobin inside the finger. Oxygen is greatly carried with the hemoglobin units in the blood. When oxygen-rich blood reaches the finger tissues, the absorption against light of the tissue will change. To detect this difference, finger is illuminated with the help of a red LED and to detect this information a probe is designed with the help of a fotoresistor. A system design have been made announcing the heart rate obtained from the designed probe in three different languages.
今天,越来越多的生物医学设备的贡献是众所周知的诊断和治疗常见疾病。在这种诊断中,心率是一个重要参数。心率是一分钟内心跳的总数。在这项研究中,心率的检测与手指内氧合血红蛋白的强度成正比。血液中的血红蛋白单位大量携带氧气。当富氧血液到达手指组织时,组织对光的吸收就会发生变化。为了检测这种差异,手指在红色LED的帮助下被照亮,为了检测这一信息,一个探针在光电电阻的帮助下被设计出来。本文设计了一个系统,用三种不同的语言显示从所设计的探头获得的心率。
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引用次数: 0
A method for liquid cryogen level measurement in cryopreservation containers 一种在低温保存容器中测量液冷液液位的方法
Pub Date : 2010-04-21 DOI: 10.1109/BIYOMUT.2010.5479866
A. U. Keskin, Cihat Koyuncu
A simple liquid sensing and measurement system for determining the level of cryogen in a tissue cryopreservation container is described. Liquid-gas boundary determination is made by detecting a thermal transient of the series-connected light emitting diodes. An electronic control and display unit located on the outer wall of the container indicates the level of cryogenic liquid, and alarms the operator if it reaches a pre-determined critical level.
描述了一种用于确定组织低温保存容器中冷冻剂水平的简单液体传感和测量系统。通过检测串联发光二极管的热瞬态来确定液气边界。位于容器外壁上的电子控制和显示单元指示低温液体的液位,并在达到预定的临界液位时向操作员发出警报。
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引用次数: 1
Classification of sleep apnea types using EEG synchronization criteria 用脑电图同步标准对睡眠呼吸暂停类型进行分类
Pub Date : 2010-04-21 DOI: 10.1109/BIYOMUT.2010.5479810
M. Aksahin, S. Aydın, H. Fırat, O. Eroğul, S. Ardıç
In this study, to obtain high quality signal features in discriminating the Central Sleep Apnea (CSA) and Obstructive Sleep Apnea (OSA) from controls, both linear and nonlinear EEG synchronization methods so called Coherence Function (CF) and Mutual Information (MI) are performed. For this purpose, sleep EEG series data collected from patients and healthy volunteers are classified by using a well known and widely used Feed-Forward Neural Network (FFNN) with respect to synchronic activities between C3 and C4 recordings. The results show that the degree of central EEG synchronization during night sleep is closely linked to sleep disorders like CSA and OSA. The MI and CF provide information in meaningful collaboration to support the clinical findings. These three groups were defined with a medical expert and can be very successfully classified by using the FFNN having two hidden layers with the average area of CF curves ranged form 0 Hz to 10 Hz and the average MI values are assigned as two features. This study is a preliminary study for classifying types of sleep apnea.
在本研究中,为了获得高质量的信号特征,以区分中枢性睡眠呼吸暂停(CSA)和阻塞性睡眠呼吸暂停(OSA)与对照组,采用线性和非线性脑电同步方法,即相干函数(CF)和互信息(MI)。为此,从患者和健康志愿者收集的睡眠脑电图系列数据通过使用众所周知且广泛使用的前馈神经网络(FFNN)对C3和C4记录之间的同步活动进行分类。结果表明,夜间睡眠中枢性脑电图同步程度与CSA、OSA等睡眠障碍密切相关。MI和CF在有意义的合作中提供信息,以支持临床发现。这三个组是由医学专家定义的,并且可以通过使用具有两个隐藏层的FFNN进行非常成功的分类,其中CF曲线的平均面积范围为0 Hz至10 Hz,平均MI值被分配为两个特征。本研究是对睡眠呼吸暂停类型进行分类的初步研究。
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引用次数: 5
Development of biomineralization solutions to facilitate the transformation of brushite (CaHPO4·2H2O) into octacalcium phosphate (Ca8(HPO4)2(PO4)4·5H2O) 促进毛刷石(CaHPO4·2H2O)转化为磷酸八钙(Ca8(HPO4)2(PO4)4·5H2O)的生物矿化溶液的开发
Pub Date : 2010-04-21 DOI: 10.1109/BIYOMUT.2010.5479865
Giray Girişken, A. Tas
Brushite (DCPD, CaHPO4·2H2O, dicalcium phosphate dihydrate) and octacalcium phosphate (OCP, Ca8(HPO4)2(PO4)4·5H2O) are two important biomineralization phases of the musculoskeletal system of living vertebrates which respectively crystallize in the very first instants of hard tissue formation accompanied by calcification, and then transform into the so-called bone mineral named as calcium-deficient hydroxyapatite (CDHA, Ca10-x(HPO4)x(PO4)6-x(OH)2-x). The utilization of these two phases in the surgical treatment of bone defects and voids has lately been the focus of interest of a significant number of research projects. Although the synthesis of DCPD is quite easy and reproducible, the same cannot be said for that of OCP. Biomineralization solutions which use DCPD as the starting material and can allow the economical transformation of DCPD into OCP have been developed in this study. This paper explains the preparation conditions of these solutions and elucidates the X-ray diffraction and infrared spectroscopy data of the phases formed.
刷石(DCPD, CaHPO4·2H2O,磷酸二氢钙)和磷酸八钙(OCP, Ca8(HPO4)2(PO4)4·5H2O)是活体脊椎动物肌肉骨骼系统中两个重要的生物矿化阶段,它们分别在硬组织形成的最初阶段结晶并伴有钙化,然后转化为所谓的骨矿物,称为缺钙羟基磷灰石(CDHA, Ca10-x(HPO4)x(PO4)6-x(OH)2-x)。在骨缺损和骨空洞的外科治疗中利用这两个阶段最近已成为许多研究项目感兴趣的焦点。虽然DCPD的合成很容易,重现性也很好,但OCP的合成就不一样了。本研究开发了以DCPD为起始材料的生物矿化解决方案,并可以将DCPD经济地转化为OCP。本文阐述了这些溶液的制备条件,并对所形成的相的x射线衍射和红外光谱数据进行了说明。
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引用次数: 2
A reconfigurable model for virtual tumour detection within a breast 乳房内虚拟肿瘤检测的可重构模型
Pub Date : 2010-04-21 DOI: 10.1109/BIYOMUT.2010.5479779
M. Solanki, V. Raja
This paper details progress towards a real time palpation simulator. We explore the potential of employing a mass spring system coupled with a haptic interface to realise this. Our motivation lies with enhancing the skills required to detect breast cancer as early as possible. However there are issues in emulating the behaviour of soft tissues using this approach, particularly if the composition of the model is inhomogeneous. Therefore our research is concerned with incorporating material properties and enhancing surface response upon contact, which is important for the simulator. We compare our model with analogous finite element models and discrete volumetric models to establish physical realism. Despite the absence of volumetric mesh, the initial evaluations show that the model can reproduce the presence of a tumour in a localised region. The model is receptive and can be reconfigured to simulate a variety of breast-tumour compositions. We look to integrate this with a deformable breast model that can be used to train the skills required for breast palpation.
本文详细介绍了实时触诊模拟器的研究进展。我们探索了利用质量弹簧系统与触觉界面相结合来实现这一目标的潜力。我们的动机在于提高尽早发现乳腺癌所需的技能。然而,使用这种方法模拟软组织的行为存在问题,特别是如果模型的组成是不均匀的。因此,我们的研究涉及到结合材料特性和增强接触时的表面响应,这对模拟器很重要。我们将我们的模型与类似的有限元模型和离散体积模型进行比较,以建立物理真实性。尽管没有体积网格,初步评估表明,该模型可以重现肿瘤在局部区域的存在。该模型具有接受性,可以重新配置以模拟各种乳腺肿瘤成分。我们希望将其与可变形的乳房模型相结合,该模型可用于训练乳房触诊所需的技能。
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引用次数: 3
The investigation of heat loss transferred from the human body via respiration in Antalya city 安塔利亚市通过呼吸从人体转移的热量损失的调查
Pub Date : 2010-04-21 DOI: 10.1109/BIYOMUT.2010.5479740
M. Bilgili, B. Şahin, E. Şimşek, A. Yaşar
In this study, the effects of seasonal weather differences city on the bio-heat losses from the human body have been investigated in Antalya. For application, the monthly atmospheric temperature, relative humidity, wind speed and atmospheric pressure data, which are observed in 2006, have been used. The sensible and latent heat losses from the human body in terms of skin surface and respiration have been calculated and compared to each other. According to the obtained results, the latent and sensible heat losses from the human body have been varied considerably from season to season. Approximately ninety percent of bio-heat losses from the human body to the surrounding is caused by the skin and the rest of 10% by respiration.
本研究在安塔利亚研究了季节气候差异对人体生物热损失的影响。在应用中,使用了2006年观测到的每月气温、相对湿度、风速和大气压数据。从皮肤表面和呼吸角度计算并比较了人体的感热和潜热损失。根据所获得的结果,人体的潜热和感热损失随季节变化很大。从人体到周围环境的生物热损失大约90%是由皮肤引起的,其余10%是由呼吸引起的。
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引用次数: 0
Use of kNN and quadratic discriminant analysis methods for sleep staging from single lead ECG recordings 使用kNN和二次判别分析方法从单导联心电图记录睡眠分期
Pub Date : 2010-04-21 DOI: 10.1109/BIYOMUT.2010.5479833
B. Yilmaz, Eren Arıkan, M. H. Asyali
Sleep consists of REM and four non-REM stages. Determining a person's sleep stage in a certain part of night sleep is performed by the technical experts using the polysomnographic recordings acquired in special sleep laboratories. The acquisition of these recordings for the sleep characterization require not only the connection of various sensors and electrodes to the subject but also spending the night in a bed which is different from the subject's own bed. In this study we investigated the feasibility of using only an electrocardiographic holter device instead of a polysomnography system used in a sleep laboratory for the sleep study and phase determination. For this purpose, single lead ECG data obtained during the night sleep (mean sleep duration 7 hours) from 18 subjects (6 men) with ages between 20 and 67 were used for sleep staging based on R-R interval values. The validation was performed by the sleep stage data previously determined by the sleep experts. Phase determination consists of R-R interval computation, feature extraction and classification studies. The features used in this study were the median value, the difference between the 75 and 25 percentile values, and mean absolute deviations of the R-R intervals computed in each 30-second epoch. The k nearest neighbor (kNN) and quadratic discriminant analysis methods based on one-versus-others approach were used as the classification tools. In the testing procedure cross-validation was employed. As a result, out of awake stage and other five sleep stages four stages were classified accurately at a rate of greater than 80%.
睡眠包括快速眼动和四个非快速眼动阶段。技术专家使用在特殊睡眠实验室获得的多导睡眠图记录来确定一个人在夜间睡眠的某个部分的睡眠阶段。为了获得这些记录以进行睡眠表征,不仅需要将各种传感器和电极连接到受试者身上,而且还需要在与受试者自己的床不同的床上过夜。在这项研究中,我们调查了在睡眠实验室中使用心电图动态心电图仪代替多导睡眠图系统进行睡眠研究和相位测定的可行性。为此,18名年龄在20 - 67岁的受试者(6名男性)在夜间睡眠(平均睡眠时间7小时)中获得的单导联心电图数据被用于基于R-R间隔值的睡眠分期。通过睡眠专家先前确定的睡眠阶段数据进行验证。相位确定包括R-R区间计算、特征提取和分类研究。本研究中使用的特征是中位数,75和25百分位值之间的差值,以及每个30秒epoch计算的R-R区间的平均绝对偏差。使用k近邻(kNN)和基于一对一方法的二次判别分析方法作为分类工具。在检验过程中采用交叉验证。结果,在清醒阶段和其他五个睡眠阶段中,有四个阶段被准确分类,准确率超过80%。
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引用次数: 2
Denoising of Electroretinogram signals using empirical mode decomposition 基于经验模态分解的视网膜电图信号去噪
Pub Date : 2010-04-21 DOI: 10.1109/BIYOMUT.2010.5479849
F. Latifoğlu, Ayşegül Güven, Uğur Durmuş, A. Öner
Clinical Electrophysiologic tests derived from human eyes are the tests that use to review whole visual pathways and they are important for ophthalmology and neuro ophthalmology. Electroretinographies is one of the electrophysiological tests often used to investigate the electrical response of the retinal layers from retinal pigment epithelium up to the occipital cortex. ERG signals have two important amplitudes that are used to diagnose diseases by doctors. These are negative a wave and positive b wave. Implicit times of the a and b waves are also meaningful to diagnose. ERG signals have small amplitudes (about μV). Because of this reason it is significant to separate the signal from the noise and interference that occurs as a result of movement. In this study, we propose using a new technique, called the empirical mode decomposition to denoised ERG responses. The Empirical Mode Decomposition is a signal processing method for analyzing nonlinear and nonstationary signals. ERG signals which are nonstationary signals are decomposed into a series of Intrinsic Mode Functions and then noise and interference are eliminated. Finally ERG signals which have signal to noise ratio less or equal than 10 dB are reconstructed. As a result we successfully obtained denoised ERG signals.
来源于人眼的临床电生理测试是用来检查整个视觉通路的测试,在眼科学和神经眼科学中具有重要意义。视网膜电图是一种常用于研究视网膜色素上皮至枕皮质层电反应的电生理测试方法。ERG信号有两个重要的振幅,医生用它们来诊断疾病。这是负a波和正b波。a波和b波的隐式时间对诊断也有意义。ERG信号振幅较小(约μV)。由于这个原因,将信号与由于运动而产生的噪声和干扰分开是很重要的。在这项研究中,我们提出使用一种称为经验模式分解的新技术来去噪ERG响应。经验模态分解是一种分析非线性和非平稳信号的信号处理方法。ERG信号是一种非平稳信号,它被分解成一系列的固有模态函数,然后去除噪声和干扰。最后对信噪比小于或等于10 dB的ERG信号进行重构。结果,我们成功地获得了去噪的ERG信号。
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引用次数: 4
期刊
2010 15th National Biomedical Engineering Meeting
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