Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479795
S. Toker, Z. Evis, A. Tezcaner
In this study, microstructural, mechanical properties and biocompatibility of hydroxyapatite (HA) doped with constant yttrium (Y3+) and varying fluoride (F-) compositions were investigated. HA was synthesized by precipitation method and sintered at 1100°C for 1 hour. Y3+ doping led to increase in material densities while F- doping led to decrease. In x-ray diffraction (XRD) analysis, no secondary phases were formed in pure and doped samples. Decrease in lattice parameters were observed upon substitutions of ions. Scanning electron microscopy (SEM) results showed that addition of doping ions resulted in smaller grains. In Fourier transform infrared (FTIR) spectroscopy analysis, novel bands were observed in F-ion doped samples in addition to characteristic HA bands, indicating the substitution of F- ions. The highest microhardness was obtained for the sample doped with 2.5%Y3+, 1%F-. Lower microhardness values were obtained with increased F- doping. In methylthiazolyldiphenyltetrazolium (MTT) assay, which was performed for cell proliferation, Y3+ and F- incorporation was found to improve cell proliferation on discs. In SEM analysis cells were found to attach and proliferate on disc surfaces. Alkaline phosphatase (ALP) assay showed that it was possible to improve differentiation of cells on the discs by doping the HA with an optimum amount of F- ion. Dissolution tests revealed that structural stability of HA was improved with F- ion incorporation.
{"title":"Investigation of microstructure, microhardness and biocompatibility characteristics of yttrium and fluoride doped hydroxyapatite","authors":"S. Toker, Z. Evis, A. Tezcaner","doi":"10.1109/BIYOMUT.2010.5479795","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479795","url":null,"abstract":"In this study, microstructural, mechanical properties and biocompatibility of hydroxyapatite (HA) doped with constant yttrium (Y3+) and varying fluoride (F-) compositions were investigated. HA was synthesized by precipitation method and sintered at 1100°C for 1 hour. Y3+ doping led to increase in material densities while F- doping led to decrease. In x-ray diffraction (XRD) analysis, no secondary phases were formed in pure and doped samples. Decrease in lattice parameters were observed upon substitutions of ions. Scanning electron microscopy (SEM) results showed that addition of doping ions resulted in smaller grains. In Fourier transform infrared (FTIR) spectroscopy analysis, novel bands were observed in F-ion doped samples in addition to characteristic HA bands, indicating the substitution of F- ions. The highest microhardness was obtained for the sample doped with 2.5%Y3+, 1%F-. Lower microhardness values were obtained with increased F- doping. In methylthiazolyldiphenyltetrazolium (MTT) assay, which was performed for cell proliferation, Y3+ and F- incorporation was found to improve cell proliferation on discs. In SEM analysis cells were found to attach and proliferate on disc surfaces. Alkaline phosphatase (ALP) assay showed that it was possible to improve differentiation of cells on the discs by doping the HA with an optimum amount of F- ion. Dissolution tests revealed that structural stability of HA was improved with F- ion incorporation.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124397034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479792
Cafer Budak, M. Bahattin Kurt
The beginning of the knowledge about the effects of electromagnetic fields on human body is almost simultaneous with the knowledge on electromagnetic fields themselves. The desire for the knowledge in order to become well aware of electromagnetic fields is increasing as electronics are spread. Especially the field of the effects of mobile phones on human brain is actually one of the most attractive topics since there has been no device which is used as near as mobile phone to the brain. The most important issue is that the heat release which caused by mobile phone. The heat release rate was defined here as Specific Absorption Rate (SAR). In this study, a model was developed by using different electrical frequencies of the brain tissues. By using this model, the SAR variation graphs for the effects of different mobile phones on brain were obtained through Finite difference Time Domain (FDTD) method.
{"title":"Investigation of electromagnetic energy accumulated in the brain by mobile phones for different frequencies","authors":"Cafer Budak, M. Bahattin Kurt","doi":"10.1109/BIYOMUT.2010.5479792","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479792","url":null,"abstract":"The beginning of the knowledge about the effects of electromagnetic fields on human body is almost simultaneous with the knowledge on electromagnetic fields themselves. The desire for the knowledge in order to become well aware of electromagnetic fields is increasing as electronics are spread. Especially the field of the effects of mobile phones on human brain is actually one of the most attractive topics since there has been no device which is used as near as mobile phone to the brain. The most important issue is that the heat release which caused by mobile phone. The heat release rate was defined here as Specific Absorption Rate (SAR). In this study, a model was developed by using different electrical frequencies of the brain tissues. By using this model, the SAR variation graphs for the effects of different mobile phones on brain were obtained through Finite difference Time Domain (FDTD) method.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124836708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479804
Fatma Oya Ayturk, F. Ates, Umut Akgün, M. Karahan, C. Yucesoy
In this study, the adequency of the current amplitudes during intraoperative force measurement of human gracilis muscle is investigated. During anterior cruciate ligament (ACL) reconstruction, gracilis muscle isometric force is measured after stimulating the muscle by different current amplitudes (130, 140, 150 and 160 mA) at fixed knee angles 90°, 60° and 30°. When the knee angle is fixed at 60° and 90°, the mean maximum forces are measured to be 203.8±18.75N and 160.65±8.04N respectively. At 60° knee angle; forces exerted at different current amplitudes are higher than the ones obtained at other knee angles. Due to fatigue, a substantial decrease in maximum force is observed when the knee angle is fixed at 30°. At all conditions, a tetanus state without any fluctuations and minor standard deviations are observed. As a result, it is observed that all stimulation amplitudes tested in this experiment are safe and reliable to measure human gracilis muscle force intraoperatively.
{"title":"Assessment of the adequency of the current amplitude during intraoperative force measurement of human gracilis muscle","authors":"Fatma Oya Ayturk, F. Ates, Umut Akgün, M. Karahan, C. Yucesoy","doi":"10.1109/BIYOMUT.2010.5479804","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479804","url":null,"abstract":"In this study, the adequency of the current amplitudes during intraoperative force measurement of human gracilis muscle is investigated. During anterior cruciate ligament (ACL) reconstruction, gracilis muscle isometric force is measured after stimulating the muscle by different current amplitudes (130, 140, 150 and 160 mA) at fixed knee angles 90°, 60° and 30°. When the knee angle is fixed at 60° and 90°, the mean maximum forces are measured to be 203.8±18.75N and 160.65±8.04N respectively. At 60° knee angle; forces exerted at different current amplitudes are higher than the ones obtained at other knee angles. Due to fatigue, a substantial decrease in maximum force is observed when the knee angle is fixed at 30°. At all conditions, a tetanus state without any fluctuations and minor standard deviations are observed. As a result, it is observed that all stimulation amplitudes tested in this experiment are safe and reliable to measure human gracilis muscle force intraoperatively.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124676551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479809
T. Bilici, N. Topaloglu, O. Tabakoglu, H. Kalaycıoğlu, A. Kurt, A. Sennaroğlu, M. Gülsoy
Laser tissue welding tensile strength tests were performed on Wistar rat skin by using diode-pumped and fiber-coupled Thulium (Tm:YAP) laser system emitting at 1980-nm, which is developed for medical applications. The success of laser tissue welding at 100 mW and 5 s in both continuous wave and modulated operation modes were compared with the results by suture technique. Tm:YAP laser at 100 mW, 5 second (34,66 W/cm2) was found successful for tissue welding studies.
{"title":"Welding by Thulium laser system: Tensile strength tests","authors":"T. Bilici, N. Topaloglu, O. Tabakoglu, H. Kalaycıoğlu, A. Kurt, A. Sennaroğlu, M. Gülsoy","doi":"10.1109/BIYOMUT.2010.5479809","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479809","url":null,"abstract":"Laser tissue welding tensile strength tests were performed on Wistar rat skin by using diode-pumped and fiber-coupled Thulium (Tm:YAP) laser system emitting at 1980-nm, which is developed for medical applications. The success of laser tissue welding at 100 mW and 5 s in both continuous wave and modulated operation modes were compared with the results by suture technique. Tm:YAP laser at 100 mW, 5 second (34,66 W/cm2) was found successful for tissue welding studies.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124718246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479808
M. Özgören, M. Sakar, A. Öniz
In this study, a low-cost data acquisition (DAQ) system has been developed to measure the body temperature from multiple points using a sensor network approach. This system collects raw data with long-term recording and stores for further analysis. Contact and non-contact types of temperature sensors were used. The system was especially designed for measuring from head during electroencephalography (EEG) recordings. The system can record data during the normal daily activities because of its portability. Observing body thermo-regulation in a time period of 24 to 36 hours and finding the correlation with the ambient temperature requires very long time physiological recording. Thus, it has been made possible to record temperature everywhere and in day or night time without limiting the mobility. Using different type of temperature sensors and measuring the ambient temperature allows determining the temperature differences and the thermal response of body separately. As a result, a low cost, compact, portable, and durable measuring system with using two types of temperature sensors has been designed for considering easy and reliable measurements.
{"title":"Contact/non-contact sensor mesh for body temperature monitoring","authors":"M. Özgören, M. Sakar, A. Öniz","doi":"10.1109/BIYOMUT.2010.5479808","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479808","url":null,"abstract":"In this study, a low-cost data acquisition (DAQ) system has been developed to measure the body temperature from multiple points using a sensor network approach. This system collects raw data with long-term recording and stores for further analysis. Contact and non-contact types of temperature sensors were used. The system was especially designed for measuring from head during electroencephalography (EEG) recordings. The system can record data during the normal daily activities because of its portability. Observing body thermo-regulation in a time period of 24 to 36 hours and finding the correlation with the ambient temperature requires very long time physiological recording. Thus, it has been made possible to record temperature everywhere and in day or night time without limiting the mobility. Using different type of temperature sensors and measuring the ambient temperature allows determining the temperature differences and the thermal response of body separately. As a result, a low cost, compact, portable, and durable measuring system with using two types of temperature sensors has been designed for considering easy and reliable measurements.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"176 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121325151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
X-Ray Flouroscopy (XF) is one of the most commonly used imaging techniques in interventional radiology, with the main disadvantage of low soft tissue contrast. XFM tries to overcome this using information from MRI. In XFM, anatomical details gathered from a priori MRI is overlaid on top of live XF images during interventions. To achieve this, registration between MRI and XF spaces should be done, for which markers visible both in MRI and XF could be used. Considering all the requirements of the final project goal, which is a comprehensive XFM software for early clinical research, Extensible Imaging Platform (XIP) is chosen for its development environment. XIP is supported by groups like caBIG and Siemens Corporate Research.
{"title":"XIP software for XFM (X-Ray fused with MRI)","authors":"Emre Özdal, Abdulkadir Yazici, Aytaç Durmaz, Cengizhan Öztürk","doi":"10.1109/BIYOMUT.2010.5479739","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479739","url":null,"abstract":"X-Ray Flouroscopy (XF) is one of the most commonly used imaging techniques in interventional radiology, with the main disadvantage of low soft tissue contrast. XFM tries to overcome this using information from MRI. In XFM, anatomical details gathered from a priori MRI is overlaid on top of live XF images during interventions. To achieve this, registration between MRI and XF spaces should be done, for which markers visible both in MRI and XF could be used. Considering all the requirements of the final project goal, which is a comprehensive XFM software for early clinical research, Extensible Imaging Platform (XIP) is chosen for its development environment. XIP is supported by groups like caBIG and Siemens Corporate Research.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134158121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479818
T. Topal, E. Değirmenci, R. Boyacioglu, V. Arpinar, B. M. Eyüboğlu
Conductivity distribution can be imaged using Magnetic Resonance Electrical Impedance Tomography (MREIT) technique. This technique is composed of Magnetic Resonance Imaging (MRI) and Electrical Impedance Tomography (EIT) techniques and based on imaging conductor object using MRI system while applying electrical current to the conductor. In an MREIT system, current should be applied to the object in synchrony with the MR pulse sequence. In this study, a current source compatible with MRI system has been developed. The current source is designed so as to be controlled by the computer and used by an interface. The results obtained by the MREIT system, applying 20 mA current to the experimental phantom with the designed current source, are given and discussed in the study.
{"title":"Current source design for MREIT technique and its experimental application","authors":"T. Topal, E. Değirmenci, R. Boyacioglu, V. Arpinar, B. M. Eyüboğlu","doi":"10.1109/BIYOMUT.2010.5479818","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479818","url":null,"abstract":"Conductivity distribution can be imaged using Magnetic Resonance Electrical Impedance Tomography (MREIT) technique. This technique is composed of Magnetic Resonance Imaging (MRI) and Electrical Impedance Tomography (EIT) techniques and based on imaging conductor object using MRI system while applying electrical current to the conductor. In an MREIT system, current should be applied to the object in synchrony with the MR pulse sequence. In this study, a current source compatible with MRI system has been developed. The current source is designed so as to be controlled by the computer and used by an interface. The results obtained by the MREIT system, applying 20 mA current to the experimental phantom with the designed current source, are given and discussed in the study.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"28 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133089092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479789
B. E. Demir, Funda Yorulmaz, I. Guler
Electrocardiogram (ECG) is a signal designed to work as result of contraction of the heart muscle that make up the electrical biopotentials, using body surface electrodes obtained by obtaining are marked. The result of the heart losing healty working conditions,disturbances on freguency and amplitude of ECG signals recorded by electrocardiograph according to the healty ECG signal, occurs. The study performed, is a work to help educational problem in the fields of Faculty of Medicine and Biomedical Engineering Education,and calibration of ECG devices without a real heart.In this study, heart rhythm disorders under the supervision of the microcontroller designed a system that may occur due to be displayed in a virtual environment analysis of all disease has been made with prepared simulator (virtual reality application) to reduce medical errors and the spending time and costing at the same time provide more effectively healty service with well-trained physicians.
{"title":"Microcontroller controlled ECG simulator","authors":"B. E. Demir, Funda Yorulmaz, I. Guler","doi":"10.1109/BIYOMUT.2010.5479789","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479789","url":null,"abstract":"Electrocardiogram (ECG) is a signal designed to work as result of contraction of the heart muscle that make up the electrical biopotentials, using body surface electrodes obtained by obtaining are marked. The result of the heart losing healty working conditions,disturbances on freguency and amplitude of ECG signals recorded by electrocardiograph according to the healty ECG signal, occurs. The study performed, is a work to help educational problem in the fields of Faculty of Medicine and Biomedical Engineering Education,and calibration of ECG devices without a real heart.In this study, heart rhythm disorders under the supervision of the microcontroller designed a system that may occur due to be displayed in a virtual environment analysis of all disease has been made with prepared simulator (virtual reality application) to reduce medical errors and the spending time and costing at the same time provide more effectively healty service with well-trained physicians.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130891214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479769
C. B. Top, N. G. Gencer
It is possible to measure tissue impedance by inducing eddy currents in the tissue, and measuring the magnetic fields caused by these induced eddy currents. In the presented work, an analytical solution is developed for the induced voltage in the receiver coil(s) in the presence of a small volume inhomogeneity in an otherwise homogeneous tissue. Analytical solutions are compared with numerical FDTD (Finite Difference Time Domain) simulations. The differences in magnetic flux were up to 23% when inhomogeneity was located 10 mm deep, whereas that difference was 6% for the inhomogeneity depth of 30 mm.
{"title":"Analytical solution for contactless electrical impedance measurement","authors":"C. B. Top, N. G. Gencer","doi":"10.1109/BIYOMUT.2010.5479769","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479769","url":null,"abstract":"It is possible to measure tissue impedance by inducing eddy currents in the tissue, and measuring the magnetic fields caused by these induced eddy currents. In the presented work, an analytical solution is developed for the induced voltage in the receiver coil(s) in the presence of a small volume inhomogeneity in an otherwise homogeneous tissue. Analytical solutions are compared with numerical FDTD (Finite Difference Time Domain) simulations. The differences in magnetic flux were up to 23% when inhomogeneity was located 10 mm deep, whereas that difference was 6% for the inhomogeneity depth of 30 mm.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130850512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-04-21DOI: 10.1109/BIYOMUT.2010.5479817
T. Pasaoglu, Burak Güçlu
Computer games have become an increasing part of many young people's daily lives. Excessive gaming may become a kind of behaviored addiction similar to gambling and may turn to a biological addiction. In order to accept this hypothesis there should be significant difference between the subject groups which points out to the dopaminergic reward system. As a result of our study, excessive game players showed higher skin conductance fluctuations and increased heart rate than non-excessive players. During game sessions cortisol hormone levels and heart rate fluctuations decreased in both groups. However, we found that there is a negative correlation between beta-endorphin and skin conductance fluctuations and pozitive correlation between heart rate mean and dopamine. These correlations may contribute to the behaviored addiction hypothesis and be a step to understand the mechanisms underlying the excessive game playing.
{"title":"Comparing the neuroendocrine hormone levels and psychophysiological parameters between excessive game players and normal people","authors":"T. Pasaoglu, Burak Güçlu","doi":"10.1109/BIYOMUT.2010.5479817","DOIUrl":"https://doi.org/10.1109/BIYOMUT.2010.5479817","url":null,"abstract":"Computer games have become an increasing part of many young people's daily lives. Excessive gaming may become a kind of behaviored addiction similar to gambling and may turn to a biological addiction. In order to accept this hypothesis there should be significant difference between the subject groups which points out to the dopaminergic reward system. As a result of our study, excessive game players showed higher skin conductance fluctuations and increased heart rate than non-excessive players. During game sessions cortisol hormone levels and heart rate fluctuations decreased in both groups. However, we found that there is a negative correlation between beta-endorphin and skin conductance fluctuations and pozitive correlation between heart rate mean and dopamine. These correlations may contribute to the behaviored addiction hypothesis and be a step to understand the mechanisms underlying the excessive game playing.","PeriodicalId":180275,"journal":{"name":"2010 15th National Biomedical Engineering Meeting","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132688029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}