E. Gusbi, Farag Eltaib, A. Abrahem, Walid Benbubaker, I. Alhudiri, Sameera Al-dabea, H. Alemam, Nada Elgriw, Adel Elshukri, Ahmed Hamil, Latifa bettamer, N. Enattah, A. Elzagheid
Background/Aim: Cancer is a major public health problem worldwide with significant association with deaths and disabilities. Monitoring the cancer incidence is important, but it has never been assessed prospectively in southern part of Libya. The aim of this study was to estimate the cancer incidence and incidence rates in southern part of Libya as part of the monitoring of the cancer incidence in Libya. Materials and Methods: This was a retrospective study based on data collected between January 2016 and December 2018, the total number of cases diagnosed with different types of cancer reported to the Sabha Cancer Center was 665. All Libyan males and females who were diagnosed with any type of cancer were included in this study. Results: Overall cancer was more among female than male; it affected 414 (62.3%) females and 251 (37.7%) males. With 374 (56.2%) of all recorded cases being found in Sabha, the city documented the highest percentage of all cases found in these regions. According to the study analysis, the most diagnosed type of cancer in southern Libya was breast cancer, with 318 (47.8%) cases, followed by colorectal cancer (118, 17.7%), prostate cancer (60, 9%), leukemia (31, 4.7), lung cancer (23, 3.5), ovarian cancer (18, 2.7%), and lymphoma (17, 2.6%). Among females, breast cancer remained the most reported cancer site, with a decrease in the incidence rate from 146 (45.9%) in 2016 – 73 (23%) cases in 2018. Colorectal cancer was the second most common cancer with a slight increase in the incidence rate from 34 (28.8%) in 2016 to 43 (36.4%) cases in 2018. Leukemia and ovarian cancer ranked third and fourth most-reported cancer sites, respectively. For males, colorectal cancer remained the most reported cancer site during the study period with a slight increase in the incidence rate from 23 (9.16%) in 2016 to 32 (12.7%) cases in 2018. Prostate cancer was the second most common cancer and decreased in the incidence rate from 34 (13.5%) in 2016 to 14 (5.57%) cases in 2018, followed by leukemia and lymphoma. The elderly age groups of ≥70 years account for 17% of the cancer cases. There was a steady rise in incidence rate of all cancers from age <14 years to 69 years and was greater in women. In elderly people (≥70 years), cancer rate was higher in male than female. Conclusion: The results of this study suggest the importance of further epidemiological and etiological studies to further reveal factors contributing to the cancer incidence trends in Libya.
{"title":"Cancer incidence in Southern Libya: Updated report from 2016 to 2018","authors":"E. Gusbi, Farag Eltaib, A. Abrahem, Walid Benbubaker, I. Alhudiri, Sameera Al-dabea, H. Alemam, Nada Elgriw, Adel Elshukri, Ahmed Hamil, Latifa bettamer, N. Enattah, A. Elzagheid","doi":"10.4103/LJMS.LJMS_74_20","DOIUrl":"https://doi.org/10.4103/LJMS.LJMS_74_20","url":null,"abstract":"Background/Aim: Cancer is a major public health problem worldwide with significant association with deaths and disabilities. Monitoring the cancer incidence is important, but it has never been assessed prospectively in southern part of Libya. The aim of this study was to estimate the cancer incidence and incidence rates in southern part of Libya as part of the monitoring of the cancer incidence in Libya. Materials and Methods: This was a retrospective study based on data collected between January 2016 and December 2018, the total number of cases diagnosed with different types of cancer reported to the Sabha Cancer Center was 665. All Libyan males and females who were diagnosed with any type of cancer were included in this study. Results: Overall cancer was more among female than male; it affected 414 (62.3%) females and 251 (37.7%) males. With 374 (56.2%) of all recorded cases being found in Sabha, the city documented the highest percentage of all cases found in these regions. According to the study analysis, the most diagnosed type of cancer in southern Libya was breast cancer, with 318 (47.8%) cases, followed by colorectal cancer (118, 17.7%), prostate cancer (60, 9%), leukemia (31, 4.7), lung cancer (23, 3.5), ovarian cancer (18, 2.7%), and lymphoma (17, 2.6%). Among females, breast cancer remained the most reported cancer site, with a decrease in the incidence rate from 146 (45.9%) in 2016 – 73 (23%) cases in 2018. Colorectal cancer was the second most common cancer with a slight increase in the incidence rate from 34 (28.8%) in 2016 to 43 (36.4%) cases in 2018. Leukemia and ovarian cancer ranked third and fourth most-reported cancer sites, respectively. For males, colorectal cancer remained the most reported cancer site during the study period with a slight increase in the incidence rate from 23 (9.16%) in 2016 to 32 (12.7%) cases in 2018. Prostate cancer was the second most common cancer and decreased in the incidence rate from 34 (13.5%) in 2016 to 14 (5.57%) cases in 2018, followed by leukemia and lymphoma. The elderly age groups of ≥70 years account for 17% of the cancer cases. There was a steady rise in incidence rate of all cancers from age <14 years to 69 years and was greater in women. In elderly people (≥70 years), cancer rate was higher in male than female. Conclusion: The results of this study suggest the importance of further epidemiological and etiological studies to further reveal factors contributing to the cancer incidence trends in Libya.","PeriodicalId":18055,"journal":{"name":"Libyan Journal of Medical Sciences","volume":"30 1","pages":"11 - 16"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82339995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coeliac disease is a chronic inflammatory autoimmune enteropathy that affects around 1% of people worldwide. It is caused by ingestion of gluten products in people who are genetically predisposed. The pathogenesis involves multifactorial factors of genetic, gluten exposure, and environmental triggers. HLA-DQ2 and HLA-DQ8 are the main responsible genes that contribute to the development of coeliac disease. Both innate and adaptive immune plays role in the pathogenesis. In this article, we will review the causes and pathogenesis of coeliac disease development.
{"title":"Coeliac disease etiology and pathogenesis","authors":"Ali A. Elmdaah","doi":"10.4103/LJMS.LJMS_87_20","DOIUrl":"https://doi.org/10.4103/LJMS.LJMS_87_20","url":null,"abstract":"Coeliac disease is a chronic inflammatory autoimmune enteropathy that affects around 1% of people worldwide. It is caused by ingestion of gluten products in people who are genetically predisposed. The pathogenesis involves multifactorial factors of genetic, gluten exposure, and environmental triggers. HLA-DQ2 and HLA-DQ8 are the main responsible genes that contribute to the development of coeliac disease. Both innate and adaptive immune plays role in the pathogenesis. In this article, we will review the causes and pathogenesis of coeliac disease development.","PeriodicalId":18055,"journal":{"name":"Libyan Journal of Medical Sciences","volume":"30 1","pages":"2 - 5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74238726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First epileptic seizure and electroencephalography: An overview","authors":"J. Rissardo, Ana Letícia Fornari Caprara","doi":"10.4103/LJMS.LJMS_4_21","DOIUrl":"https://doi.org/10.4103/LJMS.LJMS_4_21","url":null,"abstract":"","PeriodicalId":18055,"journal":{"name":"Libyan Journal of Medical Sciences","volume":"118 1","pages":"39 - 39"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90377031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: The aim of the study was to assess the success and possible complications of closed reduction (CR) treatment of developmental hip dysplasia (DHD) in late-diagnosed children and explores its relation to the acetabular index (AI) measurement prior to treatment. Patients and Methods: Twenty-three consecutive patients with dislocated hips, 16 unilateral and 7 bilateral (30 hips), were retrospectively included in the study. They were admitted to the specialist pediatric orthopedic unit of the University Hospital (Tripoli Medical Center) in Tripoli, Libya. There were 21 females and 2 males with an average age at diagnosis of 17 months (range from 14 to 31 months). Their average follow-up period was 3 years (2–5 years), and none of them received treatment prior to diagnosis. All patients received prior inpatient skin traction for at least 2 weeks followed by CR with soft tissue release (adductor tenotomy), hip spica applied and maintained for an average of 3 months. Patients who had a failure of reduction or resubluxation at follow-up went for open reduction and a reconstruction procedure. Results: CR was successful in 27 hips (90%), failed in 3 (10%) other, the average age of the successful reduction group was 20.5 months, while that of the open reduction group, it was 23 months ( P = 0.25). The average AI of the CR group was 39.0°, while that of the open reduction group, it was 42.7° ( P = 0.15); 6.7% of patients with an AI of <40° had a failure of CR, while 16.7% of an AI of >40° had a failure of CR of the hip ( P = 0.46). No complications of treatment were recorded at follow-up. Conclusion: Staged CR of DHD in older children in the hands of experienced specialists is still a valid means of their treatment, especially in developing countries with limited resources. There is a relatively higher failure rate of CR, the older the child is and the higher the AI.
{"title":"Closed reduction for developmental hip dysplasia in lately diagnosed walking age children","authors":"Majdi Alakkari, Nabil A. Alageli","doi":"10.4103/LJMS.LJMS_85_20","DOIUrl":"https://doi.org/10.4103/LJMS.LJMS_85_20","url":null,"abstract":"Aim: The aim of the study was to assess the success and possible complications of closed reduction (CR) treatment of developmental hip dysplasia (DHD) in late-diagnosed children and explores its relation to the acetabular index (AI) measurement prior to treatment. Patients and Methods: Twenty-three consecutive patients with dislocated hips, 16 unilateral and 7 bilateral (30 hips), were retrospectively included in the study. They were admitted to the specialist pediatric orthopedic unit of the University Hospital (Tripoli Medical Center) in Tripoli, Libya. There were 21 females and 2 males with an average age at diagnosis of 17 months (range from 14 to 31 months). Their average follow-up period was 3 years (2–5 years), and none of them received treatment prior to diagnosis. All patients received prior inpatient skin traction for at least 2 weeks followed by CR with soft tissue release (adductor tenotomy), hip spica applied and maintained for an average of 3 months. Patients who had a failure of reduction or resubluxation at follow-up went for open reduction and a reconstruction procedure. Results: CR was successful in 27 hips (90%), failed in 3 (10%) other, the average age of the successful reduction group was 20.5 months, while that of the open reduction group, it was 23 months ( P = 0.25). The average AI of the CR group was 39.0°, while that of the open reduction group, it was 42.7° ( P = 0.15); 6.7% of patients with an AI of <40° had a failure of CR, while 16.7% of an AI of >40° had a failure of CR of the hip ( P = 0.46). No complications of treatment were recorded at follow-up. Conclusion: Staged CR of DHD in older children in the hands of experienced specialists is still a valid means of their treatment, especially in developing countries with limited resources. There is a relatively higher failure rate of CR, the older the child is and the higher the AI.","PeriodicalId":18055,"journal":{"name":"Libyan Journal of Medical Sciences","volume":"38 1","pages":"25 - 27"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88369223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.4103/LJMS.LJMS_108_20
B. Bashir
{"title":"Does COVID-19 influence the platelet indices?","authors":"B. Bashir","doi":"10.4103/LJMS.LJMS_108_20","DOIUrl":"https://doi.org/10.4103/LJMS.LJMS_108_20","url":null,"abstract":"","PeriodicalId":18055,"journal":{"name":"Libyan Journal of Medical Sciences","volume":"26 1","pages":"1 - 1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79630807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Aim: Penile fracture is a relatively rare urological emergency. The aim of this study was to review the experience with 69 consecutive cases in Benghazi, Libya. Patients and Methods: Records of 69 penile fracture cases who presented between January 1997 and December 2018 to Hawari Center for Urology, Benghazi, Libya were retrospectively reviewed. Penile fracture diagnosis was based on classic history and typical physical signs. Surgical exploration was performed for all patients under spinal anesthesia. Results: The most common mechanism of penile fracture was self-inflicted forceful bending (manipulation) of erected penis which account for 39 (56.5%) patients, followed by vigorous sexual intercourse in 19 (27.5%) patients, masturbation in five (7.2%) patients, rolling over an erect penis in bed in five (7.2%) patients, and slipping in WC in one (1.5%) patient. Clinical features at presentation include intense pain in 97%, sudden audible popping sound in 87%, rapid de tumescence in 94.2%, followed by development of swelling and ecchymosis in all patients (100%). All patients were treated surgically and no intraoperative or immediate postoperative complications were encountered. During the follow-up period, all patients had normal urinary steam and normal sexual function was experienced by 97.1% of the patients. Five patients (7.2%) had long-term complications: penile hypoesthesia (one patient), painful erection (one patient), penile curvature of <15o on erection (one patient), and mild erectile dysfunction (two patients). Most patients were discharged home on postoperative day 1. Conclusion: Penile fracture occurred mainly due to forceful sexual manipulation of erected penis, and diagnosis can be made clinically. Immediate surgical repair is the only option to avoid complications.
{"title":"Clinical appraisal of corpora cavernosa injuries (penile fracture): Retrospective review of 69 patients in Benghazi, Libya","authors":"Muftah Elkhafifi, Wael Y. Alaorfi","doi":"10.4103/LJMS.LJMS_60_20","DOIUrl":"https://doi.org/10.4103/LJMS.LJMS_60_20","url":null,"abstract":"Background and Aim: Penile fracture is a relatively rare urological emergency. The aim of this study was to review the experience with 69 consecutive cases in Benghazi, Libya. Patients and Methods: Records of 69 penile fracture cases who presented between January 1997 and December 2018 to Hawari Center for Urology, Benghazi, Libya were retrospectively reviewed. Penile fracture diagnosis was based on classic history and typical physical signs. Surgical exploration was performed for all patients under spinal anesthesia. Results: The most common mechanism of penile fracture was self-inflicted forceful bending (manipulation) of erected penis which account for 39 (56.5%) patients, followed by vigorous sexual intercourse in 19 (27.5%) patients, masturbation in five (7.2%) patients, rolling over an erect penis in bed in five (7.2%) patients, and slipping in WC in one (1.5%) patient. Clinical features at presentation include intense pain in 97%, sudden audible popping sound in 87%, rapid de tumescence in 94.2%, followed by development of swelling and ecchymosis in all patients (100%). All patients were treated surgically and no intraoperative or immediate postoperative complications were encountered. During the follow-up period, all patients had normal urinary steam and normal sexual function was experienced by 97.1% of the patients. Five patients (7.2%) had long-term complications: penile hypoesthesia (one patient), painful erection (one patient), penile curvature of <15o on erection (one patient), and mild erectile dysfunction (two patients). Most patients were discharged home on postoperative day 1. Conclusion: Penile fracture occurred mainly due to forceful sexual manipulation of erected penis, and diagnosis can be made clinically. Immediate surgical repair is the only option to avoid complications.","PeriodicalId":18055,"journal":{"name":"Libyan Journal of Medical Sciences","volume":"30 1","pages":"17 - 20"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90787881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angioedema and type I allergic reactions are rare but recognized side effects of thrombolytic drugs. They are more commonly reported during or after the treatment of acute ischemic stroke with alteplase compared to myocardial infarction (MI). Herein, we present a 68-year-old male patient who developed oropharyngeal and facial angioedema and urticarial skin rash on the upper limbs after treatment of acute MI with tenecteplase.
{"title":"Facial and oropharyngeal angioedema after tenecteplase treatment of acute myocardial infarction","authors":"Aboubaker Alzwi, Anis Abobaker, Ali Fietoury","doi":"10.4103/ljms.ljms_65_20","DOIUrl":"https://doi.org/10.4103/ljms.ljms_65_20","url":null,"abstract":"Angioedema and type I allergic reactions are rare but recognized side effects of thrombolytic drugs. They are more commonly reported during or after the treatment of acute ischemic stroke with alteplase compared to myocardial infarction (MI). Herein, we present a 68-year-old male patient who developed oropharyngeal and facial angioedema and urticarial skin rash on the upper limbs after treatment of acute MI with tenecteplase.","PeriodicalId":18055,"journal":{"name":"Libyan Journal of Medical Sciences","volume":"45 1","pages":"201 - 203"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77516359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The aim is to determine the pattern of cytokines secretion by assessing interleukins (IL-1, IL-6, and tumor necrosis factor-alpha (TNF-α) in pulmonary tuberculosis patients. Materials and Methods: A cross-sectional study was conducted on 146 consecutive (54 males and 92 females) sputum positive for tuberculosis and 38 apparently healthy age- and sex-matched sputum negative for tuberculosis as control were recruited between May 2016 and June 2017. A volume of 5 mL of blood samples was collected for the determination of serum IL-1, IL-6 and TNF-α using the ELISA method. Results: There was a higher cytokine mean ± standard error of the mean for tuberculosis subjects (95.77 ± 6.68 pg/mL; 107.54 ± 14.76 pg/mL, 122.09 ± 16.55 pg/ml) and controls (79.88 ± 3.53 pg/ml; 78.35 ± 6.82 pg/ml; 94.11 ± 14.08 pg/ml) for interleukin-1, interleukin-6, and TNF-α, respectively, when compared. There was strong correlation between mean values of IL-6 and TNF-α (r = 0.72315, P < 0.05). There was significance difference (P < 0.05) observed in the mean serum concentrations of cytokines among the genders (P < 0.05). Conclusion: The study revealed that IL-1, IL-6, TNF-α are important biological markers for tuberculosis disease.
{"title":"Pro-inflammatory cytokine profile of pulmonary tuberculosis patients in central hospital, Agbor Nigeria","authors":"C. Isibor, R. Okojie, E. Ophori, S. Omonigho","doi":"10.4103/ljms.ljms_41_19","DOIUrl":"https://doi.org/10.4103/ljms.ljms_41_19","url":null,"abstract":"Background: The aim is to determine the pattern of cytokines secretion by assessing interleukins (IL-1, IL-6, and tumor necrosis factor-alpha (TNF-α) in pulmonary tuberculosis patients. Materials and Methods: A cross-sectional study was conducted on 146 consecutive (54 males and 92 females) sputum positive for tuberculosis and 38 apparently healthy age- and sex-matched sputum negative for tuberculosis as control were recruited between May 2016 and June 2017. A volume of 5 mL of blood samples was collected for the determination of serum IL-1, IL-6 and TNF-α using the ELISA method. Results: There was a higher cytokine mean ± standard error of the mean for tuberculosis subjects (95.77 ± 6.68 pg/mL; 107.54 ± 14.76 pg/mL, 122.09 ± 16.55 pg/ml) and controls (79.88 ± 3.53 pg/ml; 78.35 ± 6.82 pg/ml; 94.11 ± 14.08 pg/ml) for interleukin-1, interleukin-6, and TNF-α, respectively, when compared. There was strong correlation between mean values of IL-6 and TNF-α (r = 0.72315, P < 0.05). There was significance difference (P < 0.05) observed in the mean serum concentrations of cytokines among the genders (P < 0.05). Conclusion: The study revealed that IL-1, IL-6, TNF-α are important biological markers for tuberculosis disease.","PeriodicalId":18055,"journal":{"name":"Libyan Journal of Medical Sciences","volume":"116 5-6","pages":"188 - 191"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91493284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Vitamin D deficiency is a worldwide health problem and has been associated with religion, faith, caste, education, and socioeconomic status. Scientific evidence indicates that adequate levels of Vitamin D have important implications for the management of health problems. Aim: The aim of this study is to investigate the prevalence of Vitamin D deficiency and associated risk factors among Libyan females. Patients and Methods: This cross-sectional study included 262 female patients presented with nonspecific musculoskeletal and bone pain at Seoul Hospital in Tripoli, Libya. Vitamin D status was measured and risk factors for Vitamin D deficiency were assessed. Results: The mean age ± standard error of mean (SEM) of participants was 40.8 ± 0.9 years (range 18-80 years). In general, approximately 87.7% of the patients (n = 262) have serum Vitamin D concentrations below normal (<30 ng/mL). The mean serum 25-hydroxyvitamin D (25(OH)D) concentration of patients was 13.98 ± 10.2 ng/ml. About 50.8% had 25(OH)D-levels <10 ng/mL which is characterized as severe Vitamin D deficiency, 27.5% had 25(OH)D-levels <20 ng/ml, defined as Vitamin D deficiency. About 9.1% of patients had insufficient Vitamin D, and only 12.6% had sufficient Vitamin D status defined as 25(OH)D-levels ≥30 ng/ml. Conclusions: Our data show that patients with generalized body aches, fatigue, and nonspecific bone pains, all have a significant relationship with Vitamin D deficiency strongly related to risk factors such as inadequate exposure to sunlight, wearing covering clothes, niqab, hijab, low dietary Vitamin D intake, and Vitamin D supplementation.
{"title":"Serum Vitamin D levels and associated risk factors among libyan females living in Tripoli, Libya: A cross-sectional study","authors":"Manal Al-Graiw, M. Draid, A. Zaidi, H. Al-Griw","doi":"10.4103/ljms.ljms_64_20","DOIUrl":"https://doi.org/10.4103/ljms.ljms_64_20","url":null,"abstract":"Background: Vitamin D deficiency is a worldwide health problem and has been associated with religion, faith, caste, education, and socioeconomic status. Scientific evidence indicates that adequate levels of Vitamin D have important implications for the management of health problems. Aim: The aim of this study is to investigate the prevalence of Vitamin D deficiency and associated risk factors among Libyan females. Patients and Methods: This cross-sectional study included 262 female patients presented with nonspecific musculoskeletal and bone pain at Seoul Hospital in Tripoli, Libya. Vitamin D status was measured and risk factors for Vitamin D deficiency were assessed. Results: The mean age ± standard error of mean (SEM) of participants was 40.8 ± 0.9 years (range 18-80 years). In general, approximately 87.7% of the patients (n = 262) have serum Vitamin D concentrations below normal (<30 ng/mL). The mean serum 25-hydroxyvitamin D (25(OH)D) concentration of patients was 13.98 ± 10.2 ng/ml. About 50.8% had 25(OH)D-levels <10 ng/mL which is characterized as severe Vitamin D deficiency, 27.5% had 25(OH)D-levels <20 ng/ml, defined as Vitamin D deficiency. About 9.1% of patients had insufficient Vitamin D, and only 12.6% had sufficient Vitamin D status defined as 25(OH)D-levels ≥30 ng/ml. Conclusions: Our data show that patients with generalized body aches, fatigue, and nonspecific bone pains, all have a significant relationship with Vitamin D deficiency strongly related to risk factors such as inadequate exposure to sunlight, wearing covering clothes, niqab, hijab, low dietary Vitamin D intake, and Vitamin D supplementation.","PeriodicalId":18055,"journal":{"name":"Libyan Journal of Medical Sciences","volume":"44 1","pages":"169 - 173"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74943506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salivary gland lymphomas are rare, constituting 1.7% of all salivary gland neoplasms. They are uncommon before 50 years of age predominantly involving parotid gland. The most common histopathological forms of non Hodgkin lymphoma include mucosa associated lymphoid tissue lymphoma followed by follicular lymphoma and diffuse large B cell lymphoma. A retrospective study was conducted in a tertiary health care centre over a span of six years on patients with salivary gland lymphomas. Their clinicopathological features, staging and treatment modalities were determined. The mean age was 63.3 years with four males and two females. All patients had parotid gland involvement with one showing simultaneous involvement of submandibular gland. Histopathologically there were three cases of low grade B-cell lymphoma, two cases of high grade lymphoma and one case of Hodgkin lymphoma. Three patients were found in early stage and three in advanced stage disease. Lymphomas must be considered in the differential diagnosis of a salivary gland swelling although they are quite uncommon. They predominantly involve parotid gland. The selection of treatment modalities is based on histologic subtyping and staging of lymphoma with better prognosis as compared to other extranodal non Hodgkin lymphoma.
{"title":"Primary salivary gland lymphomas: A case series","authors":"S. Fatima, Rabab Badri, W. Siddiqui, A. Alshehri","doi":"10.4103/ljms.ljms_51_20","DOIUrl":"https://doi.org/10.4103/ljms.ljms_51_20","url":null,"abstract":"Salivary gland lymphomas are rare, constituting 1.7% of all salivary gland neoplasms. They are uncommon before 50 years of age predominantly involving parotid gland. The most common histopathological forms of non Hodgkin lymphoma include mucosa associated lymphoid tissue lymphoma followed by follicular lymphoma and diffuse large B cell lymphoma. A retrospective study was conducted in a tertiary health care centre over a span of six years on patients with salivary gland lymphomas. Their clinicopathological features, staging and treatment modalities were determined. The mean age was 63.3 years with four males and two females. All patients had parotid gland involvement with one showing simultaneous involvement of submandibular gland. Histopathologically there were three cases of low grade B-cell lymphoma, two cases of high grade lymphoma and one case of Hodgkin lymphoma. Three patients were found in early stage and three in advanced stage disease. Lymphomas must be considered in the differential diagnosis of a salivary gland swelling although they are quite uncommon. They predominantly involve parotid gland. The selection of treatment modalities is based on histologic subtyping and staging of lymphoma with better prognosis as compared to other extranodal non Hodgkin lymphoma.","PeriodicalId":18055,"journal":{"name":"Libyan Journal of Medical Sciences","volume":"15 1","pages":"192 - 195"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87838926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：