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Selective Spinal Anesthesia in a Patient with Low Ejection Fraction Who Underwent Emergent Below-Knee Amputation in a Resource-Constrained Setting. 选择性脊髓麻醉在低射血分数患者在资源有限的情况下接受紧急膝下截肢。
IF 2.9 Q3 ANESTHESIOLOGY Pub Date : 2020-10-12 eCollection Date: 2020-01-01 DOI: 10.2147/LRA.S277152
Hailemariam Mulugeta, Abebayehu Zemedkun, Hailemariam Getachew

Patients with congestive heart failure have a high risk of perioperative major adverse cardiac events and death. The major perioperative goal of management in patients with low ejection fraction is maintaining hemodynamic stability. Evidence is scarce on the safety of a certain anesthetic technique for patients with heart failure. In this report, we present a 48-year-old man with ischemic dilated cardiomyopathy and low-output congestive heart failure (estimated ejection fraction of 27%) who underwent emergent below-knee amputation under selective spinal anesthesia without any apparent complications. We believe that selective spinal anesthesia can be a useful alternative anesthetic technique in patients with low ejection fraction undergoing emergent lower limb surgery. We showed evidence-based and customized anesthetic management of a high-risk patient with the available equipment and resources. This report will hopefully show the contextual challenges of the perioperative care of critically ill patients in resource-constrained settings.

充血性心力衰竭患者围手术期发生主要心脏不良事件和死亡的风险较高。低射血分数患者围手术期治疗的主要目标是维持血流动力学稳定性。关于某种麻醉技术对心力衰竭患者的安全性的证据很少。在本报告中,我们报告了一位48岁的缺血性扩张型心肌病和低输出量充血性心力衰竭(估计射血分数为27%)的男性患者,他在选择性脊髓麻醉下接受了紧急膝下截肢手术,没有任何明显的并发症。我们认为,选择性脊髓麻醉可以作为一种有用的替代麻醉技术,为低射血分数患者进行紧急下肢手术。我们展示了在现有设备和资源的情况下对高危患者进行循证和定制的麻醉管理。本报告将有望展示资源受限环境下危重病人围手术期护理的环境挑战。
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引用次数: 1
Anesthetic Techniques: Focus on Lumbar Erector Spinae Plane Block. 麻醉技术:以腰竖肌脊柱平面阻滞为主。
IF 2.9 Q3 ANESTHESIOLOGY Pub Date : 2020-09-25 eCollection Date: 2020-01-01 DOI: 10.2147/LRA.S233274
Serkan Tulgar, Muhammed Enes Aydin, Ali Ahiskalioglu, Alessandro De Cassai, Yavuz Gurkan

Defined in the last decade, erector spinae plane block (ESPB) is one of the more frequently used interfacial plans, and it has been the most discussed block among the recently defined techniques. Lumbar ESPB administered at lumbar levels is relatively novel and is a new horizon for regional anesthesia and pain practice. In this article, we aim to explain and introduce different approaches and explain the possible mechanism of action of lumbar ESPB. The objective of this review is to analyze the case reports, clinical and cadaveric studies about lumbar ESPB that have been published to date. We performed a search in "Pubmed" and "Google Scholar" database. After a selection of the relevant studies, 59 articles were found eligible and were included in this review. While we believe that lumbar ESPB is reliable and easy, we suggest that its efficacy and indications should be verified with anatomical and clinical studies, and its safety should be confirmed with pharmacokinetic studies. Moreover, the possibility of complications must be considered.

在过去的十年中,直立脊柱平面块(ESPB)是最常用的接口平面之一,也是最近定义的技术中讨论最多的块。腰椎ESPB在腰椎水平给药是相对新颖的,是区域麻醉和疼痛实践的新领域。在本文中,我们旨在解释和介绍不同的方法,并解释腰椎ESPB的可能作用机制。本综述的目的是分析迄今为止已发表的关于腰椎ESPB的病例报告、临床和尸体研究。我们在“Pubmed”和“Google Scholar”数据库中进行了搜索。在对相关研究进行筛选后,59篇符合条件的文章被纳入本综述。虽然我们认为腰椎ESPB是可靠和容易的,但我们建议其疗效和适应症应通过解剖学和临床研究来验证,其安全性应通过药代动力学研究来证实。此外,必须考虑并发症的可能性。
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引用次数: 36
Postoperative Thoracic Epidural Analgesia: Adverse Events from a Single-Center Series of 3126 Patients. 术后胸椎硬膜外镇痛:来自3126例患者的单中心系列不良事件。
IF 2.9 Q3 ANESTHESIOLOGY Pub Date : 2020-09-10 eCollection Date: 2020-01-01 DOI: 10.2147/LRA.S272410
Alberto Manassero, Matteo Bossolasco, Mattia Carrega, Giuseppe Coletta

Purpose: Thoracic epidural analgesia (TEA) has been shown to reduce postsurgical morbidity and mortality; nevertheless, major and minor complications can occur. We report our 10-year experience with TEA and incidence of complications.

Patients and methods: Patients received continuous infusion TEA (0.2% ropivacaine and 2 µg ml-1 fentanyl) to control postoperative pain. Every 8 hours, the acute pain service recorded the analgesia regimen and occurrence of side effects. The initial infusion rate was tapered daily in response to improvement in pain symptoms or occurrence of side effects.

Results: A total of 3126 patients received TEA. The median age was 65 years (range, 18-94) and the duration of catheter placement was 3.5 days (range, 2-8). Three major complications were identified (1:1042): two subarachnoid blocks and one epidural abscess which led to permanent sequela (1:3126). Minor complications were hypotension (4.8%), pruritus (4.4%), accidental catheter removal (3.7%), insertion site inflammation (2.5%), motor weakness (2.0%), postoperative nausea and vomiting (1.8%), catheter disconnection (1.9%), catheter occlusion (0.3%), post-dural puncture headache (0.5%), and catheter fragment retention (0.06%), which were the reasons for a 7.4% rate of early discontinuation of epidural analgesia. No occurrence of epidural hematoma, local anesthetic systemic toxicity, and cardiovascular/respiratory depression was recorded.

Conclusion: Postoperative TEA is an advanced technique that poses certain difficulties that can subvert its great potential. While serious complications were rare, minor complications occurred more often and affected the postoperative course negatively. A risk/benefit evaluation of each patient should be done before employing the technique.

目的:胸部硬膜外镇痛(TEA)已被证明可以降低术后发病率和死亡率;然而,可发生或大或小的并发症。我们报告10年的TEA治疗经验和并发症的发生率。患者和方法:术后持续输注TEA(0.2%罗哌卡因+ 2µg ml-1芬太尼)控制疼痛。急性疼痛服务每8小时记录一次镇痛方案及不良反应发生情况。根据疼痛症状的改善或副作用的发生,每日逐渐减少初始输注速率。结果:3126例患者接受了TEA治疗。中位年龄为65岁(范围18-94),置管时间为3.5天(范围2-8)。发现了三个主要并发症(1:10 . 42):两个蛛网膜下阻塞和一个硬膜外脓肿,导致永久性后遗症(1:3 . 126)。轻微并发症为低血压(4.8%)、瘙痒(4.4%)、意外拔管(3.7%)、插入部位炎症(2.5%)、运动无力(2.0%)、术后恶心呕吐(1.8%)、导管断开(1.9%)、导管阻塞(0.3%)、硬膜穿刺后头痛(0.5%)、导管碎片潴留(0.06%),这是导致硬膜外镇痛早期停药率7.4%的原因。未发生硬膜外血肿、局麻全身毒性、心血管/呼吸抑制。结论:术后TEA是一种先进的技术,但存在一定的困难,可能会破坏其巨大的潜力。虽然严重并发症罕见,但轻微并发症发生率较高,并对术后进程产生负面影响。在使用该技术之前,应对每位患者进行风险/收益评估。
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引用次数: 19
Novice and Expert Anesthesiologists' Eye-Tracking Metrics During Simulated Epidural Block: A Preliminary, Brief Observational Report. 新手和专家麻醉师在模拟硬膜外阻滞期间的眼动追踪指标:初步,简短的观察报告。
IF 2.9 Q3 ANESTHESIOLOGY Pub Date : 2020-08-21 eCollection Date: 2020-01-01 DOI: 10.2147/LRA.S267879
Emanuele Capogna, Francesco Salvi, Lorena Delvino, Andrea Di Giacinto, Matteo Velardo

Introduction: Eye tracking is the process of measuring an individual's eye movements to register their attentional behavior by using a device called an eye-tracker. Studies conducted using eye-tracking techniques have demonstrated a number of differences in eye movement parameters and patterns between experts and novices. The aim of this preliminary study was to evaluate if there are any differences in eye-tracking metrics between novice and expert anesthesiologists during the performance of an epidural block using an epidural simulator.

Methods: Seven experts and seven novices who gave their consent to this preliminary study were asked to perform an epidural technique using an epidural simulator while wearing a pair of Tobii Pro glasses. Number of fixations, fixation duration, heat maps and scan-paths were examined by Tobii Pro Lab Software. Duration of the procedure was also recorded.

Results: The observation of the attentional heat map and gaze plot showed different gaze dispersion between experts and novices. The mean total duration of fixations during needle insertion and advancement and catheter introduction was lower in experts than trainees (respectively, 0.18 vs 3.56 sec; P<0.05 and 0.73 vs 2.48 sec; P<0.05). The mean fixation count was greater in experts vs trainees (5 vs 2; P<0.05). The mean duration of the epidural procedure was 104.16 (41) (trainees) vs 65.3 (32.6) seconds (experts) (P<0.05). Expert anesthesiologists spent more time fixating a more specific target location (eg, the point of the epidural needle rather than the syringe's barrel) whilst novices split their attention between tracking their tools and the target location.

Discussion: Eye tracking may have interesting implications for the creation of assessment programs, which distinguish skill level through the use of gaze behavior, and may be a promising tool for monitoring training progress towards the development of expertise.

眼动追踪是通过一种叫做眼动仪的设备来测量一个人的眼球运动来记录他们的注意力行为的过程。使用眼球追踪技术进行的研究表明,专家和新手在眼球运动参数和模式上存在许多差异。本初步研究的目的是评估新手和专家麻醉师在使用硬膜外模拟器进行硬膜外阻滞时的眼动追踪指标是否存在差异。方法:7名专家和7名新手同意这项初步研究,并要求他们戴上一副Tobii Pro眼镜,使用硬膜外模拟器进行硬膜外技术。用Tobii Pro Lab软件检测注视次数、注视时间、热图和扫描路径。该过程的持续时间也被记录下来。结果:注意热图和凝视图的观察显示,专家和新手的凝视离散度存在差异。专家组在插针、推进和导尿管引入期间的平均总固定时间低于实习生组(分别为0.18 vs 3.56秒;讨论:眼动追踪可能会对评估程序的创建产生有趣的影响,通过使用凝视行为来区分技能水平,并且可能是一种有前途的工具,用于监控专业知识发展的培训进展。
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引用次数: 7
Successful Dental Treatments Using Procaine Hydrochloride in a Patient Afraid of Local Anesthesia but Consenting for Allergic Testing with Lidocaine: A Case Report. 普鲁卡因成功治疗害怕局麻但同意利多卡因过敏试验的患者一例。
IF 2.9 Q3 ANESTHESIOLOGY Pub Date : 2020-08-20 eCollection Date: 2020-01-01 DOI: 10.2147/LRA.S268498
Terumi Ayuse, Shinji Kurata, Takao Ayuse

Background: We report a case in which effective dental anesthetic management was achieved using procaine hydrochloride for a patient who had an unknown history of allergic reactions to lidocaine.

Case presentation: Because the patient refused to undergo screening tests using any of the amide-type local anesthetics because of her extreme fear against local anesthetics that she had been administered previously, procaine hydrochloride, which is an ester-form local anesthetic, was the only agent to be tested on this patient at the department of dermatology. Consequent to a negative allergy test, we performed complete dental treatment using procaine hydrochloride after additional chairside drug challenge tests using minimum test dose under vital sign monitoring.

Conclusion: The success of dental treatment using procaine hydrochloride may have relieved the patient's fear of local anesthesia. We discuss an important aspect of treatment planning for patients with a history of complications during local anesthesia.

背景:我们报告了一例使用盐酸普鲁卡因对利多卡因过敏史不明的患者进行有效的牙科麻醉管理的病例。病例介绍:由于患者对以前使用过的局麻药极度恐惧,拒绝使用任何酰胺型局麻药进行筛选试验,因此在皮肤科对该患者进行测试的唯一药物是酯型局麻药盐酸普鲁卡因。由于过敏试验呈阴性,我们在生命体征监测下使用最小试验剂量进行额外的椅边药物刺激试验后,使用盐酸普鲁卡因进行了完整的牙科治疗。结论:普鲁卡因治疗成功,减轻了患者对局部麻醉的恐惧。我们讨论了一个重要的方面,治疗计划的病人与历史的并发症在局麻。
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引用次数: 1
Postoperative "Rescue" Use of Erector Spinae Plane Block After Lumbar Spine Fusion: A Report of 2 Cases. 腰椎融合术后“抢救”使用竖脊肌平面块2例报告。
IF 2.9 Q3 ANESTHESIOLOGY Pub Date : 2020-08-13 eCollection Date: 2020-01-01 DOI: 10.2147/LRA.S268973
Daniel N Kianpour, Joseph T Gundy, Jacob W Nadler, Danielle M Lindenmuth

Pain after lumbar spine fusion surgery is often difficult to control in the immediate postoperative period. Historically, opioids have been the mainstay of treatment, but are associated with many unwanted side effects as well as increased hospital length of stay. The ultrasound-guided erector spinae plane block (ESP) is a relatively safe and simple regional option for the management of acute postoperative pain after spine surgery without the technical difficulty or complications noted with paravertebral injection (eg, pneumothorax, hematoma). To date, there have been reports of preoperative placement of ESP block prior to spine surgery with some success. We present a report of two cases that highlight the efficacy of the ESP block as an early postoperative "rescue" regional anesthetic technique in lumbar spine surgery. These cases demonstrate the potential effectiveness of a "rescue" use of the ESP block in patients having uncontrolled or poorly controlled pain in the early postoperative period with no evidence of significant side effects.

腰椎融合术后疼痛往往难以在术后立即控制。从历史上看,阿片类药物一直是治疗的主要手段,但与许多不必要的副作用以及住院时间的增加有关。超声引导下的竖立者脊柱平面阻滞(ESP)是一种相对安全、简单的区域性选择,用于治疗脊柱术后急性疼痛,没有椎旁注射的技术困难或并发症(如气胸、血肿)。迄今为止,有报道称在脊柱手术前放置ESP阻滞取得了一些成功。我们报告了两个病例,强调了ESP阻滞作为腰椎手术术后早期“抢救”区域麻醉技术的有效性。这些病例表明,在术后早期疼痛不受控制或控制不佳的患者中,ESP阻滞的“抢救”可能有效,没有明显副作用的证据。
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引用次数: 3
Establishing a Technique for Pectoral II-Block Catheter Insertion with Ultrasound Guidance: A Randomized Controlled Trial. 超声引导下建立胸二段导管置入技术:一项随机对照试验。
IF 2.9 Q3 ANESTHESIOLOGY Pub Date : 2020-08-11 eCollection Date: 2020-01-01 DOI: 10.2147/LRA.S262138
Mohamed A Mansour, Ahmed Z Fouad, Sarah M Amin, Nasser M Dobal

Purpose: To assess the efficacy and safety of a modified technique for ultrasound-guided pectoral II block for postoperative pain control after mastectomy.

Methods: In this randomized controlled trial, patients were randomly allocated into two groups (40 patients each). Group I patients were subjected to ultrasound-guided pectoral II block with injection of 10 mL lidocaine 1% as a dissecting solution before attempting catheter insertion, while group II patients underwent the standard procedure without a dissecting solution. Measured outcomes included catheter visibility, pain, patient satisfaction, performance time, and complications.

Results: Compared with group II, group I had significantly lower median catheter-visibility scores, shorter block performance time, and fewer insertion attempts. Group I had a nonsignificantly higher rate of complications than group II.

Conclusion: The modified technique facilitated the procedure, shortened the catheter-insertion time, and showed higher patient satisfaction. However, it was associated with lower catheter visibility on ultrasonography. Further studies are required to confirm the present findings and assess the safety of the modified technique.

目的:评价超声引导下改良胸ⅱ阻滞技术用于乳房切除术后疼痛控制的有效性和安全性。方法:采用随机对照试验,将患者随机分为两组,每组40例。I组患者在尝试插入导管前行超声引导下的胸ⅱ阻滞,注射1%利多卡因10 mL作为夹层液,II组患者采用标准程序,不使用夹层液。测量结果包括导管可视性、疼痛、患者满意度、操作时间和并发症。结果:与II组相比,I组的中位导管可视性评分显著降低,阻滞执行时间缩短,插入次数减少。I组并发症发生率较II组无显著性增高。结论:改进后的技术操作方便,缩短了置管时间,患者满意度较高。然而,它与超声检查导管可视性较低有关。需要进一步的研究来证实目前的发现并评估改进技术的安全性。
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引用次数: 1
Emergence Agitation and Delirium: Considerations for Epidemiology and Routine Monitoring in Pediatric Patients. 出现躁动和谵妄:对儿科患者流行病学和常规监测的考虑。
IF 2.9 Q3 ANESTHESIOLOGY Pub Date : 2020-07-27 eCollection Date: 2020-01-01 DOI: 10.2147/LRA.S181459
Carrie Menser, Heidi Smith

Emergence from anesthesia can be associated with a wide spectrum of cognitive and behavioral dysregulation in children, including delirium or acute brain dysfunction. This period of neurobehavioral recovery can be further confounded by pain, anxiety, and fear. The implementation of monitoring for level of consciousness, pain, and delirium using valid pediatric tools is necessary to avoid misdiagnosis due to overlapping symptomatology and support appropriate management. Understanding the epidemiology of delirium in the postoperative setting will require consistent use of accurate terminology in the medical literature. The current interchangeable use of the terms "emergence agitation" and "emergence delirium" needs to be highlighted and awareness of differences in patient conditions and assessment tools is essential. We discuss epidemiology of emergence agitation and delirium in the pediatric population, and the challenges for future delineation of monitoring and management. Furthermore, we describe the possible impact of long-term consequences of emergence delirium among infants and children, and the necessary areas of future research.

麻醉后的出现可能与儿童广泛的认知和行为失调有关,包括谵妄或急性脑功能障碍。这段神经行为的恢复期可能会被疼痛、焦虑和恐惧进一步打乱。使用有效的儿科工具监测意识、疼痛和谵妄的水平是必要的,以避免由于重叠的症状而误诊,并支持适当的管理。了解术后谵妄的流行病学需要在医学文献中一致使用准确的术语。目前“紧急躁动”和“紧急谵妄”这两个术语的可互换使用需要得到强调,对患者情况和评估工具差异的认识至关重要。我们讨论儿科人群出现躁动和谵妄的流行病学,以及未来监测和管理的挑战。此外,我们描述了婴儿和儿童出现性谵妄的长期后果可能产生的影响,以及未来研究的必要领域。
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引用次数: 24
Anesthesia Options and the Recurrence of Cancer: What We Know so Far? 麻醉选择和癌症复发:我们目前知道什么?
IF 2.9 Q3 ANESTHESIOLOGY Pub Date : 2020-07-07 eCollection Date: 2020-01-01 DOI: 10.2147/LRA.S240567
Juan P Cata, Carlos Guerra, German Soto, Maria F Ramirez

Surgery is a critical period in the survival of patients with cancer. While resective surgery of primary tumors has shown to prolong the life of these patients, it can also promote mechanisms associated with metastatic progression. During surgery, patients require general and sometimes local anesthetics that also modulate mechanisms that can favor or reduce metastasis. In this narrative review, we summarized the evidence about the impact of local, regional and general anesthesia on metastatic mechanisms and the survival of patients. The available evidence suggests that cancer recurrence is not significantly impacted by neither regional anesthesia nor volatile or total intravenous anesthesia.

手术是癌症患者生存的关键时期。虽然原发肿瘤的切除手术已经证明可以延长这些患者的生命,但它也可以促进与转移进展相关的机制。在手术过程中,患者需要全身麻醉,有时也需要局部麻醉,以调节有利于或减少转移的机制。在这篇叙述性综述中,我们总结了局部、区域和全身麻醉对转移机制和患者生存影响的证据。现有证据表明,无论是区域麻醉,还是挥发性或全静脉麻醉,对癌症复发都没有显著影响。
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引用次数: 11
Relief of Secondary Headaches with High Thoracic Erector Spinae Plane Block. 高胸直肌脊柱平面阻滞治疗继发性头痛。
IF 2.9 Q3 ANESTHESIOLOGY Pub Date : 2020-06-22 eCollection Date: 2020-01-01 DOI: 10.2147/LRA.S249250
Nadia Hernandez, Grace Guvernator, George Ansoanuur, Michelle Ge, Precious Tabansi, Thanh-Thuy Le, Salameh S Obeidat, Johanna de Haan

Intractable headaches can be debilitating, often leading to significant distress, prolonged medical treatment, and unanticipated hospital admissions. There have been significant advances in the treatment of primary intractable headaches such as migraines, tension headaches, and cluster headaches beyond medical management. Treatments may now include interventional strategies such as trigger-point injections, peripheral nerve stimulators, or peripheral nerve and ganglion blocks. There are few studies, however, describing the use of interventional techniques for the management of intractable secondary headaches, including those attributed to injury or infection. A new regional anesthetic technique, the erector spinae plane (ESP) block, was initially used for neuropathic thoracic pain. ESP block has since been reported to provide acute and chronic pain relief of the shoulder, spine, abdomen, pelvis, thorax, and lower extremity. Additionally, there has been one case report to describe the use of the ESP block in the treatment of refractory tension headache. We report four cases of effective analgesia for intractable secondary headache resistant to medical management with high thoracic ESP blocks. In each case, the ESP block provided instant pain relief. We suggest that the findings of this case series indicate that the ESP block may be a useful intervention in patients with severe secondary headache or posterior cervical pain where conventional therapies have limited success, though more studies are necessary.

顽固性头痛会使人衰弱,通常会导致严重的痛苦、长期的医疗治疗和意外的住院。原发性顽固性头痛,如偏头痛、紧张性头痛和丛集性头痛的治疗已经取得了重大进展。治疗现在可能包括介入策略,如触发点注射,周围神经刺激器,或周围神经和神经节阻滞。然而,很少有研究描述了使用介入性技术来治疗顽固性继发性头痛,包括那些由损伤或感染引起的头痛。一种新的区域麻醉技术,竖脊平面阻滞(ESP),最初用于神经性胸痛。ESP阻滞已被报道用于缓解肩部、脊柱、腹部、骨盆、胸部和下肢的急性和慢性疼痛。此外,有一个案例报告描述了使用ESP阻滞治疗难治性紧张性头痛。我们报告了四例难治性继发性头痛的有效镇痛,这些头痛对高胸椎ESP阻滞治疗无效。在每种情况下,ESP阻滞都能立即缓解疼痛。我们认为,这一系列病例的研究结果表明,ESP阻滞可能是一种有效的干预措施,用于严重继发性头痛或颈后疼痛患者,在这些患者中,常规治疗效果有限,但还需要更多的研究。
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引用次数: 2
期刊
Local and Regional Anesthesia
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