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Mathematical modelling in nonlocal Mindlin’s strain gradient thermoelasticity with voids 带孔洞的非局部Mindlin应变梯度热弹性的数学建模
IF 2.2 4区 数学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2022-09-14 DOI: 10.1051/mmnp/2022042
M. Aouadi
A nonlocal theory for thermoelastic materials with voids based on Mindlin’s strain gradient theory was derived in this paper with some qualitative properties. We have also established the size effect of nonlocal heat conduction with the aids of extended irreversible thermodynamics and generalized free energy. The obtained system of equations is a coupling of three equations with higher gradients terms due to the length scale parameters ϖ and l . This poses some new mathematical difficulties due to the lack of regularity. Based on nonlinear semigroups and the theory of monotone operators, we establish existence and uniqueness of weak and strong solutions to the one dimensional problem. By an approach based on the Gearhart-HerbstPrüss-Huang theorem, we prove that the associated semigroup is exponentially stable; but not analytic.
本文在Mindlin应变梯度理论的基础上,导出了含空隙热弹性材料的非局部理论,该理论具有一定的定性性质。我们还借助扩展不可逆热力学和广义自由能建立了非局部热传导的尺寸效应。由于长度尺度参数ϖ和l,所获得的方程组是具有较高梯度项的三个方程的耦合。由于缺乏规律性,这带来了一些新的数学困难。基于非线性半群和单调算子理论,我们建立了一维问题弱解和强解的存在唯一性。利用Gearhart-HerbstPrüss-Huang定理,证明了关联半群是指数稳定的;但不是分析性的。
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引用次数: 0
The normal velocity of the population front in the "predator-prey" model “捕食者-猎物”模型中种群前沿的法向速度
IF 2.2 4区 数学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2022-08-18 DOI: 10.1051/mmnp/2022039
Evgeniy Dats, Sergey Minaev, Vladimir Gubernov, Junnosuke Okajima
The propagation of one and two-dimensional waves of populations are numerically investigated in the framework of the ``predator-prey'' model with the Arditi - Ginzburg trophic function. The propagation of prey and predator population waves and the propagation of co-existing populations' waves are considered. The simulations demonstrate that even in the case of an unstable quasi-equilibrium state of the system, which is established behind the front of a traveling wave, the propagation velocity of the joint population wave is a well-defined function. The calculated average propagation velocity of a cellular non-stationary wave front is determined uniquely for a given set of problem parameters.  The estimations of the wave propagation velocity are obtained for both the case of a plane and cellular wave fronts of populations. The structure and velocity of outward propagating circular cellular wave are investigated to clarify the local curvature and scaling effects on the wave dynamics.
在具有Arditi-Ginzburg营养函数的“捕食者-猎物”模型框架内,对种群的一维和二维波的传播进行了数值研究。考虑了猎物和捕食者种群波动的传播以及共存种群的波动的传播。模拟表明,即使在行波前沿后面建立的系统的不稳定准平衡状态下,联合总体波的传播速度也是一个定义明确的函数。对于给定的一组问题参数,计算的蜂窝非平稳波前的平均传播速度是唯一确定的。对于平面波前和群体的细胞波前,都获得了波传播速度的估计。研究了向外传播的圆形细胞波的结构和速度,以阐明局部曲率和尺度效应对波动力学的影响。
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引用次数: 0
Controllability of Delayed Discret Fornasini-Marchesini Model via Quantization and Random Packet Dropouts 基于量化和随机丢包的延迟离散Fornasini-Marchesini模型的可控性
IF 2.2 4区 数学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2022-08-17 DOI: 10.1051/mmnp/2022040
Adnen Adnen
This research is devoted to Fornasnisi-Marchesini model (FM). More precisely, the investigation of the control problem for the second model discrete-time FM. Random packet dropouts, time delays and quantization are taken into consideration in the feedback control problem simultaneously. Measured signals are quantized before being communicated. A logarithmic quantizer is utilized and quantized signal measurements are handled by a sector bound method. The random packet dropouts are modeled as a Bernoulli process. A control law model which depends on packet dropouts and quantization is formulated. Notably, we lighten the assumptions by using the Schur complement. Besides, both a state feedback controller and an observer-based output feedback controller are designed to ensure corresponding closed-loop systems asymptotically stability. Sufficient conditions on mean square asymptotic stability in terms of LMIs have been obtained. Finally, two numerical example show the feasibility of our theoretical results.
本研究致力于Fornasnisi-Marchesini模型(FM)。更确切地说,研究了第二模型离散时间调频的控制问题。反馈控制问题同时考虑了随机丢包、时延和量化。测量的信号在被通信之前被量化。使用对数量化器,并且通过扇区定界方法来处理量化的信号测量。随机分组丢弃被建模为伯努利过程。建立了一个依赖于丢包率和量化的控制律模型。值得注意的是,我们通过使用舒尔补码来减轻假设。此外,还设计了状态反馈控制器和基于观测器的输出反馈控制器,以确保相应的闭环系统渐近稳定。得到了LMIs的均方渐近稳定的充分条件。最后,通过两个算例验证了理论结果的可行性。
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引用次数: 3
Stochastic bifurcations and tipping phenomena of insect outbreak systems driven by α-stable Lévy processes α-稳定Lévy过程驱动的昆虫爆发系统的随机分叉和倾翻现象
IF 2.2 4区 数学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2022-08-08 DOI: 10.1051/mmnp/2022037
S. Yuan, Yang Li, Zhigang Zeng
In this work, we mainly characterize stochastic bifurcations and tipping phenomena of insect outbreak dynamical systems driven by $alpha$-stable L'evy processes. In one-dimensional insect outbreak model, we find the fixed points representing refuge and outbreak from the bifurcation curves, and carry out a sensitivity analysis with respect to small changes in the model parameters, the stability index and the noise intensity. We perform the numerical simulations of dynamical trajectories using Monte Carlo methods, which contribute to looking at stochastic hysteresis phenomenon. As for two-dimensional insect outbreak system, we identify the global stability properties of fixed points and  express the probability density function by the stationary solution of the nonlocal Fokker-Planck equation. Through numerical modelling,  the phase portrait makes it possible to detect critical transitions among the stable states. It is then worth describing stochastic bifurcation associated with tipping points induced by noise through a careful examination of the dynamical paths of the insect outbreak system with external forcing. The results give new insight into the sensitivity of ecosystems to realistic environmental changes represented by stochastic perturbations.
在这项工作中,我们主要描述了由$alpha$-稳定的L’evy过程驱动的昆虫爆发动力学系统的随机分叉和倾翻现象。在一维昆虫爆发模型中,我们从分岔曲线中找到了代表避难所和爆发的不动点,并对模型参数、稳定性指数和噪声强度的微小变化进行了敏感性分析。我们使用蒙特卡罗方法对动力学轨迹进行了数值模拟,这有助于观察随机滞后现象。对于二维昆虫爆发系统,我们识别了不动点的全局稳定性,并用非局部Fokker-Planck方程的平稳解表示了概率密度函数。通过数值建模,相位肖像使检测稳定状态之间的临界跃迁成为可能。因此,通过仔细研究具有外力的昆虫爆发系统的动力学路径,描述与噪声引起的临界点相关的随机分叉是值得的。研究结果为生态系统对随机扰动所代表的现实环境变化的敏感性提供了新的见解。
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引用次数: 3
Optimal control for a bone metastasis with radiotherapy model using a linear objective functional 利用线性目标泛函的放射治疗模型对骨转移进行最优控制
IF 2.2 4区 数学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2022-08-07 DOI: 10.1051/mmnp/2022038
Ariel Camacho, Enrique Diaz-Ocampo, S. Jerez
Radiation is known to cause genetic damage to highly proliferative cells such as cancer cells. However, the radiotherapy effects  to  bone cells is not completely known. In this work we present a mathematical modeling framework to test hypotheses related to the radiation-induced effects on bone metastasis. Thus, we pose an optimal control problem based  on a Komarova model describing the interactions between cancer cells and  bone cells   at a single site of bone remodeling.  The radiotherapy treatment  is included in the form of a functional which   minimizes the use of radiation using a penalty function. Moreover, we are interested to model the 'on' and the 'off' time states of the radiation schedules;  so we propose an optimal control problem with a L1-type objective functional.Bang-bang or singular arc solutions are the  obtained optimal control solutions. We characterize both solutions types   and explicitly give necessary optimality conditions for them. We present numerical simulations to analyze the different possible radiation effects on the bone and cancer cells. We also evaluate  the more significant parameters to shift from a bang-bang solution to a singular arc solution and vice versa. Additionally, we study a fractionated radiotherapy model.
众所周知,辐射会对高度增殖的细胞(如癌细胞)造成遗传损伤。然而,放射治疗对骨细胞的影响尚不完全清楚。在这项工作中,我们提出了一个数学模型框架来测试有关辐射诱导骨转移效应的假设。因此,我们提出了一个基于Komarova模型的最优控制问题,该模型描述了癌细胞和骨细胞在骨重塑的单个位点之间的相互作用。放射治疗以函数的形式包含,该函数使用惩罚函数使辐射的使用最小化。此外,我们有兴趣模拟辐射时间表的“开”和“关”时间状态;因此,我们提出了一个具有l1型目标泛函的最优控制问题。得到的最优控制解为Bang-bang解或奇异弧解。我们描述了这两种解的类型,并明确给出了它们的必要最优性条件。我们提出数值模拟来分析不同可能的辐射对骨细胞和癌细胞的影响。我们还评估了从bang-bang解到奇异弧解的更重要的参数,反之亦然。此外,我们研究了一种分割放疗模型。
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引用次数: 2
Editorial 编辑
IF 2.2 4区 数学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2022-08-04 DOI: 10.1051/mmnp/2022036
A. Ruimy, Vitaly Volpert
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引用次数: 1
DEGREE-BIASED ADVECTION-DIFFUSION ON UNDIRECTED GRAPHS/NETWORKS 无向图/网络上的度偏平流扩散
IF 2.2 4区 数学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2022-08-01 DOI: 10.1051/mmnp/2022034
E. Estrada, Manuel Miranda
There are several phenomena in nature governed by simultaneous or intermittent diffusion and advection processes. Many of these systems are networked by their own nature. Here we propose a degree-biased advection processes to undirected networks. For that purpose we define and study the degree-biased advection operator. We then develop a degree-biased advection-diffusion equation on networks and study its general properties. We give computational evidence of the utility of this new model by studying random graphs as well as a real-life patched landscape network in southern Madagascar. In the last case we show that the foraging movement of the species L. catta in this environment occurs mainly in a diffusive way with important contributions of advective motions in agreement with previous empirical observations.
自然界中有几种现象是由同时或间歇性的扩散和平流过程控制的。这些系统中的许多由于其自身性质而联网。在这里,我们提出了无向网络的度偏平流过程。为此,我们定义并研究了偏度平流算子。然后,我们在网络上发展了一个度偏平流-扩散方程,并研究了它的一般性质。我们通过研究随机图以及马达加斯加南部真实的补丁景观网络,为这种新模型的实用性提供了计算证据。在最后一种情况下,我们表明L.catta物种在这种环境中的觅食运动主要以扩散的方式发生,平流运动的重要贡献与之前的经验观测一致。
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引用次数: 1
Modelling optimal pest control of non-autonomous predator-prey interaction 非自治捕食-被捕食相互作用下害虫最优控制模型
IF 2.2 4区 数学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2022-07-26 DOI: 10.1051/mmnp/2022033
Paulo Jorge dos Santos Pinto Rebelo, Silvério Simões Rosa, César Augusto Simões Teixeira Marques da Silva
An ecological system comprehended by a pest and  its natural enemy, the predator, is considered. Parameters of system are time dependent in order to accompany their variations associated to climate evolutions. Combining the use of pesticides and of extra supply of food to predators,  we propose the eradication of pest through optimal control having those two measures as controls. Is established that the resulting problem has a unique solution. Uniqueness is obtained on the whole interval using a  recursive argument. The usefulness of model to tackle the pest population is backed by numerical simulation results.
考虑了一个由害虫及其天敌捕食者所理解的生态系统。系统的参数是时间相关的,以便伴随着与气候演变相关的变化。结合杀虫剂的使用和向捕食者提供额外的食物,我们建议通过将这两种措施作为控制措施的最佳控制来根除害虫。确定所产生的问题具有唯一的解决方案。唯一性是使用递归参数在整个区间上获得的。数值模拟结果支持了该模型在处理害虫种群方面的有用性。
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引用次数: 0
Analytical detection of stationary Turing pattern in a predator-prey system with generalist predator 广义捕食者捕食系统中平稳图灵模式的分析检测
IF 2.2 4区 数学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2022-07-22 DOI: 10.1051/mmnp/2022032
Subrata Dey, M. Banerjee, S. Ghorai
A prey-predator model with prey dependent Holling type-II functional response and a generalist predator exhibits complex dynamics in response to parameter variation. Generalist predators implicitly exploiting multiple food resources reduce predation pressure on their focal prey species that causes it to become more stable compared to a prey-predator system with specialist predator. In the temporal system, bistability and tristability are observed along with various global and local bifurcations. Existence of homogeneous and heterogeneous positive steady state solutions are shown to exist for suitable ranges of parameter values in the spatiotemporal diffusive system. Weakly nonlinear analysis using multi-scale perturbation technique is employed to derive amplitude equation for the stationary patterns near the Turing bifurcation threshold. The analytical results of the amplitude equations are validated using numerical simulations. We also identify bifurcation of multiple stable stationary patch solutions as well as dynamic pattern solution for parameter values in the Turing and Turing-Hopf regions.
具有猎物依赖型Holling ii型功能响应和通才型捕食者的捕食-捕食模型对参数变化的响应具有复杂的动态特性。多面手捕食者隐性地利用多种食物资源,减少了对其重点猎物物种的捕食压力,使其与具有专业捕食者的捕食系统相比变得更加稳定。在时间系统中,观察到双稳性和三稳性以及各种全局和局部分岔。证明了时空扩散系统在适当的参数值范围内存在齐次和非均匀正稳态解。利用多尺度摄动技术进行弱非线性分析,推导了图灵分岔阈值附近平稳模式的振幅方程。数值模拟验证了振幅方程的解析结果。在图灵和图灵-霍普夫区域中,我们还发现了多个稳定平稳斑块解的分岔以及参数值的动态模式解。
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引用次数: 4
Optimal multiplicative control of bacterial quorum sensing under external enzyme impact 外部酶作用下细菌群体感应的最优乘法控制
IF 2.2 4区 数学 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Pub Date : 2022-07-21 DOI: 10.1051/mmnp/2022031
A. Maslovskaya, C. Kuttler, A. Chebotarev, A. Kovtanyuk
The use of external enzymes provides an alternative way of reducing communication in pathogenic bacteria that may lead to the degradation of their signal and the loss of their pathogeneity. The present study considers an optimal control problem for the semilinear reaction-diffusion model of bacterial quorum sensing under the impact of external enzymes. Estimates of the solution of the controlled system are obtained, on the basis of which the solvability of the extremal problem is proved and the necessary optimality conditions of the first-order are derived. A numerical algorithm to find a solution of the optimal control problem is constructed and implemented. The conducted numerical experiments demonstrate an opportunity to build an effective strategy of the enzymes impact for treatment.
外部酶的使用提供了另一种减少致病菌通讯的方法,这可能导致其信号的降解和致病性的丧失。研究了细菌群体感应在外加酶作用下的半线性反应扩散模型的最优控制问题。得到了被控系统解的估计,在此基础上证明了极值问题的可解性,并导出了一阶最优性的必要条件。构造并实现了求解最优控制问题的数值算法。所进行的数值实验证明了建立酶对治疗影响的有效策略的机会。
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引用次数: 0
期刊
Mathematical Modelling of Natural Phenomena
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