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Therapeutic hypothermia after a cardiac arrest – Benefits, limitations, controversy 心脏骤停后治疗性低温治疗-益处,局限性,争议
Pub Date : 2018-02-18 DOI: 10.12775/MBS.2015.033
J. Szafrański, M. Szafrańska, Marcin Gierach, A. Skowrońska, W. Sinkiewicz
W pracy chcielibyśmy dokladnie przedstawic wskazania, przeciwwskazania oraz korzyści ze stosowania hipotermii terapeutycznej w leczeniu pacjentow po zatrzymaniu krązenia z przyczyn kardiologicznych. Hipotermia terapeutyczna to obnizenie wewnetrznej temperatury ciala do 32-34 stopni Celcjusza. Jest to bezpieczna i efektywna metoda zwiekszająca szanse na przezycie oraz poprawiająca prognozy neurologiczne. Skutecznośc tej metody jest potwierdzona przez  Amerykan-skie Towarzystwo Kardiologiczne oraz Europejską Komisje Resustytacyjną i zostala ona wprowadzona do wytycznych resustytacji dla doroslych. Przedstawiamy rowniez miejsce hipotermii terapeu-tycznej w świetle aktualnych wytycznych dotyczących resuscytacji, a takze wskazujemy nowe, nieuwzglednione jeszcze potencjalne mozliwości oraz nieliczne wątpliwości towarzyszące stosowaniu tej metody leczenia.
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引用次数: 0
The epidemiology of breast cancer in Kujawsko-Pomorskie Voivodship in 2006-2010 2006-2010年库贾维斯科-波莫尔斯基省乳腺癌流行病学调查
Pub Date : 2017-03-15 DOI: 10.12775/MBS.2016.035
T. Mierzwa
The analysis of the epidemiology of breast cancer in Kujawsko-Pomorskie voivodship in 2006 – 2010 in terms of the number of cases and deaths, and selected epidemiological indicators. Kujawsko-Pomorskie is the region with a great epidemiology risk in Poland. The number of cancers detected in this period was 4402, majority among the people between the ages of 50 and 69. 20% of cases were detected in cancer screening. The number of breast cancers detected in the pre-invasive stage is growing. The 5 year cure rate in the cases of breast cancer has risen.
2006 - 2010年库贾维斯科-波莫尔斯基省乳腺癌流行病学分析,包括病例数和死亡人数,以及选定的流行病学指标。库贾维斯科-波莫尔斯基是波兰流行病学风险最大的地区。在此期间发现的癌症数量为4402例,其中大多数是50至69岁的人。20%的病例是在癌症筛查中发现的。在浸润前阶段发现的乳腺癌数量正在增加。乳腺癌病例的5年治愈率有所上升。
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引用次数: 0
Role of mobility in cognitive development of children with motor deficyt – own observations of wheelchairs users 运动能力在运动缺陷儿童认知发展中的作用——对轮椅使用者的观察
Pub Date : 2017-03-15 DOI: 10.12775/MBS.2016.036
E. Mikołajewska, B. Augustyńska, D. Mikołajewski
Wheelchair plays two important roles from the physical point of view: increased mobility and body support. Two main areas of children’ development: motor and cognitive are interrelated. Thus, wheelchair supported mobility in children may also prevent many severe problems in the area of social and cognitive development. This paper aims at presentation of current state of the art and own concept concerning the role of the wheelchair-based mobility in cognitive development of children with motor deficit.
从物理角度来看,轮椅起着两个重要的作用:增加活动能力和身体支持。儿童发展的两个主要领域:运动和认知是相互关联的。因此,轮椅支持的儿童活动也可以防止许多严重的社会和认知发展问题。本文旨在介绍基于轮椅的活动在运动缺陷儿童认知发展中的作用的研究现状和自己的观点。
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引用次数: 0
Realization of the principles of rational nutrition by the universities of Bydgoszcz 比得哥什大学合理营养原则的实现
Pub Date : 2017-03-15 DOI: 10.12775/MBS.2016.034
G. Mierzwa, K. Wawrzyniak
The aim of this thesis was to evaluate if the students of universities of Bydgoszcz know the principles of proper nutrition and whether or not they follow them. The study was conducted on a group of 100 students of the universities of Bydgoszcz, 77 women and 23 men between the ages of 19 and 25. The study was carried out in the first half of 2014 using a survey method. Conclusions. Knowledge of rational nutrition and the principles of healthy eating among students of Bydgoszcz universities is quite varied and depends on the field of study. The best eating habits are characterized by technical and art faculties. Students of medical faculties and health sciences are not leaders in this field. More irregularities relating to the quality of diet is observed among students of humanities and social sciences.
本论文的目的是评估比得哥什大学的学生是否知道适当营养的原则,他们是否遵循这些原则。这项研究是在比得哥什大学的100名学生中进行的,其中77名女性和23名男性,年龄在19至25岁之间。本研究于2014年上半年采用调查法进行。结论。比得哥什大学学生对合理营养和健康饮食原则的了解情况各不相同,这取决于学习的领域。最好的饮食习惯是由技术和艺术才能决定的。医学院和健康科学专业的学生并不是这个领域的领导者。在人文社会科学专业的学生中,与饮食质量有关的不规律现象较多。
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引用次数: 0
High-dose therapy and autologous hematopoietic cel transplantation rescue in children with neuroblastoma and Ewing sarcoma 儿童神经母细胞瘤和尤文氏肉瘤的大剂量治疗和自体造血细胞移植抢救
Pub Date : 2017-03-15 DOI: 10.12775/MBS.2016.037
J. Styczyński, R. Dębski, Anna Krenska, K. Czyżewski, M. Wysocki
Background. High-dose therapy (HDT) with autologous stem cell rescue has been recently applied in very-poor-risk pediatric solid tumors. Promising data have become available with the use of high-dose busulfan in neuroblastoma (NBL) and Ewing sarcoma (ES), and with high-dose treosulfan in ES. HDT approach resulted in an encouraging outcome without toxic mortality for high-risk patients. Objective. The objective of this study is to present transplant outcomes, that is disease-free-survival and overall survival in children with high-risk NBL and ES undergoing auto-HSCT. Patients and methods. A total number of 47 NBL and 20 ES auto-HSCT performed between 2004 and 2016 in a single transplant center were included in this analysis. Results. Probability of 3-years pOS was 0.79±0.06 and 0.46±0.14 for NBL and ES patients, respectively. Relapse incidence at 3 years after HSCT was 0.37±0.08 and 0.26±0.11 for NBL and ES patients, respectively. The number of relapses at 3 years after HSCT was 15/47 in NBL and 6/20 in ES. Busulfan-based vs treosulfan-based conditioning in ES patients resulted in lower relapse and death rates. NBL and ES patients transplanted in complete remission (CR1) had lower relapse rates and lower death rates than patients at CR>1. Conclusion. Obtained results of auto-HSCT confirm the therapeutic benefit for children with NBL and ES. Recent reports on current practice of HSCT in Europe indicate HDT with auto-HSCT as a standard of care in pediatric patients with high risk or relapsed NBL and ES.
背景。自体干细胞抢救的高剂量治疗(HDT)最近被应用于极低风险的儿童实体瘤。在神经母细胞瘤(NBL)和尤文氏肉瘤(ES)中使用高剂量丁硫丹,以及在ES中使用高剂量曲硫丹,已经获得了有希望的数据。HDT方法对高危患者无毒性死亡,结果令人鼓舞。目标。本研究的目的是展示移植结果,即接受自体造血干细胞移植的高风险NBL和ES患儿的无病生存和总生存。患者和方法。该分析包括2004年至2016年在单个移植中心进行的47例NBL和20例ES自体造血干细胞移植。结果。NBL和ES患者的3年pOS概率分别为0.79±0.06和0.46±0.14。移植后3年的复发率,NBL和ES患者分别为0.37±0.08和0.26±0.11。HSCT后3年的复发率NBL为15/47,ES为6/20。以布磺胺为基础的治疗与以曲硫胺为基础的治疗相比,ES患者的复发率和死亡率更低。完全缓解期(CR1)移植的NBL和ES患者的复发率和死亡率低于CR>1的患者。结论。获得的自体造血干细胞移植结果证实了对NBL和ES患儿的治疗益处。最近关于欧洲目前HSCT实践的报告表明,HDT +自体HSCT是高风险或复发的NBL和ES患儿的标准治疗方法。
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引用次数: 2
Share of reactive oxygen species (ROS) in inflammatory bowel disease. The diagnostic usefulness of selected markers. Part 1 炎症性肠病中活性氧(ROS)的份额。所选标记的诊断有用性。第1部分
Pub Date : 2017-03-15 DOI: 10.12775/MBS.2016.033
D. Kupczyk, B. Augustyńska, G. Mierzwa
Malfunctioning of environmental, immunologic or genetic mechanisms brings about a disorder of system homeostasis, which results in the development of diseases of arduous course. Inflammatory bowel diseases are a group of disorders which house a pathological inflammation of the wall of the gastrointestinal tract. It is postulated that one reason for the resulting changes may be free radical reactions. As a result of the ongoing inflammation under the course of the disease an influx of neutrophils into the lumen begins. Although endoscopic examination constitutes an irreplaceable method in the evaluation of the resulting changes, laboratory tests are an essential tool in the diagnostic process. In recent years it has been proven that the role of faecal calprotectin as a non-invasive test can be used to differentiate organic and functional gastrointestinal diseases, and evaluate remission or exacerbation of inflammatory bowel disease [6,28]. It has also been noted that there is a need to seek other new markers that would facilitate the diagnosis.
由于环境、免疫或遗传机制的故障,导致系统稳态紊乱,从而导致病程艰苦的疾病的发生。炎症性肠病是一组由胃肠道壁的病理性炎症引起的疾病。据推测,产生这种变化的原因之一可能是自由基反应。由于疾病过程中持续的炎症,中性粒细胞开始涌入管腔。虽然内窥镜检查是评估所产生的变化的不可替代的方法,但实验室检查是诊断过程中必不可少的工具。近年来,粪便钙保护蛋白作为一种无创检测方法被证明可以用于区分器质性和功能性胃肠道疾病,并评估炎症性肠病的缓解或加重[6,28]。也有人指出,有必要寻找其他新的标志物,以促进诊断。
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引用次数: 0
Review of research tools for assessment of performance of nursing staff 护理人员绩效评估研究工具综述
Pub Date : 2017-03-15 DOI: 10.12775/MBS.2016.038
Marta Szara, A. Ksykiewicz-Dorota, J. Klukow
Managers willingly use performance as the key element in the motivation of employees, evaluation of their work, as well as an important indicator in the bonus system. The measurement of performance allows not only the explanation of the cause of the occurrence of a deviation in the efficiency of nurses’ work, but also facilitates the implementation of actions improving the quality of performance of occupational activities.  The objective of the study was analysis of literature concerning the structure and principles of the application of instruments used for the assessment of performance of nurses. The review of literature pertaining to the tools for the evaluation of efficiency of performance of nurses showed a large number of international reports; however, there is a total lack in the Polish literature. Analysis of literature allowed the formulation of the following conclusions: in Poland, there is a lack of studies concerning the measurement of performance of nurses. The performance of nurses should be measured by the tool which enables its evaluation in a multi-aspect context, and possesses a high reliability and validity.
管理者愿意将绩效作为激励员工、评价员工工作的关键因素,也愿意将绩效作为奖金制度的重要指标。绩效的测量不仅可以解释护士工作效率发生偏差的原因,还可以促进提高职业活动绩效质量的行动的实施。本研究的目的是分析文献有关结构和原则的应用工具,用于评估护士的表现。对有关评估护士绩效效率的工具的文献回顾显示了大量的国际报告;然而,在波兰文学中完全缺乏。对文献的分析可以得出以下结论:在波兰,缺乏关于护士绩效衡量的研究。护理人员的工作表现应采用测评工具进行测评,使其能够在多方面进行评估,具有较高的信度和效度。
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引用次数: 4
Communication in patients with disorders of consciousness – lessons learned From InteRDoCTor project 意识障碍患者的沟通——InteRDoCTor项目的经验教训
Pub Date : 2017-03-10 DOI: 10.12775/MBS.2016.032
J. Komendziński, E. Mikołajewska, D. Mikołajewski, B. Augustyńska
Thanks to recent advances in health care an increased number of patients may recover from  severe brain injuries, but some of them are still assessed as non-responsive. Reliance on behavioural measures in communication with DoC patients seems be too prone to errors. There is need for solutions providing more objective attempts of bidirectional communication (intentional questions/commands and adequate related responses) in patients with DoC using significant processed by the patient stimuli and novel technologies (EEG-, fMRI-, BCI-based, etc.) based on recent scientific and clinical evidences. Such communication may be fulfilled even in the absence of behavior. This article aims at assessment the extent to which current possibilities in the area of devices for extended communication has been exploited, including own experiences within InteRDoCTor project.
由于最近医疗保健的进步,越来越多的患者可能从严重的脑损伤中康复,但其中一些患者仍被评估为无反应。在与DoC患者的沟通中依赖行为措施似乎太容易出错。需要在最新的科学和临床证据的基础上,利用患者刺激的显著处理和新技术(EEG-, fMRI-, bci -等),为DoC患者提供更客观的双向交流(有意的问题/命令和适当的相关反应)的解决方案。这种交流即使在没有行为的情况下也可以实现。本文旨在评估当前扩展通信设备领域的可能性被利用的程度,包括自己在InteRDoCTor项目中的经验。
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引用次数: 0
The costs of endovascular in-hospital treatment of critical limb ischemia in patients who finally inderwent leg amputation. A one-center experience 最终接受截肢的重症肢体缺血患者的血管内住院治疗费用。一个中心的体验
Pub Date : 2017-02-18 DOI: 10.12775/MBS.2016.029
J. Budzyński, Liliana Wnęk, Wioletta Banaś, Beata Czerniak
Background. Currently, the average amputation free survival in patients with critical limb ischemia (CLI) amounts to 76% after one year of follow-up. Such poor prognosis raises the question: is revascularization in patients with CLI cost-effective? The aim of this study was to conduct a cost analysis of vascular care in patients with CLI. The aim of this study was to conduct a cost analysis of vascular care in patients with CLI. Patients and methods. A retrospective cost analysis of in-hospital endovascular treatment in 37 patients with CLI who underwent secondary leg amputation between January 2012 and June 2015. Results. The average length of time between the first endovascular procedure due to CLI and leg amputation amounted to 214 days (range 8-1088 days). The total cost of hospitalizations before leg amputation amounted to 687 603.13 PLN, which is, on average, 18 583.87 PLN per patient, and 86.84 PLN per person per day for living with the preserved lower limb. The total costs associated with the patients who had undergone leg amputation amounted to 404 883.24 PLN, which is an average of 10 942.79 PLN per patient. Previous endovascular procedures accounted for 58.9% of this sum and 37.1% to total management costs for the patients. Conclusions. The cost per day of endovascular treatment that makes it possible to live with two lower limbs did not exceed the established cost-effectiveness threshold. Lower limb amputation increases the costs of in-hospital patient care by 59%, represents financial wastage for the hospital, and incurs other costs not easily measured.
背景。目前,重症肢体缺血(CLI)患者的平均无截肢生存率在随访1年后达到76%。如此糟糕的预后提出了一个问题:对CLI患者进行血运重建术是否具有成本效益?本研究的目的是对CLI患者的血管护理进行成本分析。本研究的目的是对CLI患者的血管护理进行成本分析。患者和方法。2012年1月至2015年6月间37例行二次截肢的CLI患者的住院血管内治疗的回顾性成本分析。结果。从CLI引起的第一次血管内手术到截肢的平均时间为214天(范围8-1088天)。截肢前的住院总费用为687 603.13兹罗提,平均每位患者为18 583.87兹罗提,保留下肢每人每天为86.84兹罗提。截肢患者的总费用为404 883.24 PLN,平均为10 942.79 PLN /例。先前的血管内手术占该金额的58.9%,占患者总管理费用的37.1%。结论。每天的血管内治疗费用没有超过既定的成本-效果阈值,这使得双下肢生活成为可能。下肢截肢使住院病人的护理费用增加了59%,这对医院来说是一种财政浪费,并产生了不易衡量的其他费用。
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引用次数: 0
Emotional condition of patients subjected to endovascular surgery due to chronić ischemia of the l ower limbs 下肢慢性缺血致血管内手术患者的情绪状况
Pub Date : 2017-02-17 DOI: 10.12775/MBS.2016.031
Beata Czerniak, J. Budzyński, Wioletta Banaś
Introduction. Emotional status of a patient who underwent a surgery is an important element in the recovery process. The aim of the study was to assess changes in positive and negative emotions in patients subjected to endovascular procedure due to chronic ischemia of the lower limbs and the determination of the factors affecting that process. Materials and methods. 63 patients subjected to endovascular surgery due to chronic ischemia participated in the study. The study group included persons aged 46 to 87 (median 65 years). The following tools were used: a questionnaire on demographic and medical data, Larsen & Diener Affect Intensity Measure Scale, modified Charles Carver's MiniCOPE (situational version) Inventory of coping with stress measurement, Berlin social support scale and Multidimensional Health Locus of Control Scale. Medical data on the hospitalization time, type of anesthesia and the type of a surgery procedure was also used in the study. Results. Statistically significant increase of the positive emotions intensity was observed in the studied group of patients Me=9 (min. 0, max. 23) before the surgery and Me=13 (min. 4, max. 27) after surgery and reduced level of negative emotions from Me=10 (min. 1, max. 24) to Me=3 (min. 0, max. 15). Conclusions. In patients treated for chronic ischemia of the lower limbs an endovascular intervention (revascularization of lower limbs) decreased the negative emotions level and increased the positive ones. Health locus of control does not influence the emotional status change in the studied subjects. Patients with higher levels of perceived social, emotional and instrumental support are characterized by smaller increase of positive emotions intensity after endovascular surgery. Patients with lower levels of perceived instrumental support are characterized by smaller decrease of negative emotions intensity after endovascular surgery. Strategies used to cope with stress related to surgery do not affect the emotional condition change in persons subjected to endovascular surgery. Number of symptoms following endovascular surgery is a predictor of the level of negative emotions.
介绍。手术患者的情绪状态是恢复过程中的一个重要因素。本研究的目的是评估由于下肢慢性缺血而接受血管内手术的患者的积极和消极情绪的变化,并确定影响这一过程的因素。材料和方法。63例因慢性缺血行血管内手术的患者参与了研究。研究组包括46 - 87岁(中位65岁)的人。使用的工具有:人口统计和医学数据问卷、Larsen & Diener影响强度测量量表、修正的Charles Carver应对压力量表(情境版)、柏林社会支持量表和多维健康控制源量表。研究还使用了住院时间、麻醉类型和手术程序类型的医疗数据。结果。实验组患者的积极情绪强度有统计学意义的提高(Me=9, min = 0, max = 0)。23)术前,Me=13(最小4,最大13)。27)手术后,Me的负面情绪水平降低=10(最小1,最大1)。24)到Me=3(最小0,最大0)。15)。结论。在下肢慢性缺血患者中,血管内介入治疗(下肢血运重建术)可降低患者的负性情绪水平,提高患者的正性情绪水平。健康控制点不影响被试情绪状态的变化。感知社会、情感和工具支持水平较高的患者在血管内手术后积极情绪强度的增加较小。感知工具支持水平较低的患者,其负性情绪强度在血管内手术后的下降幅度较小。用于应对手术相关压力的策略不会影响血管内手术患者的情绪状况变化。血管内手术后症状的数量是负面情绪水平的预测指标。
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