Adrianna Trofimiuk, Klaudia Koza, Paweł Grzelązka, J. Budzyński
Cele. Przewlekle niedokrwienie konczyn dolnych (PNKD) jest trzecim, co do czestości, schorzeniem sercowo- naczyniowym, dotyczącym okolo 20-30% doroslej populacji. Określenie czynnikow ryzyka PNKD jest istotne dla wczesnej diagnozy i wlaściwego leczenia chorych. Celem pracy bylo porownanie czestości wystepowania poszczegolnych czynnikow ryzyka u pacjentow leczonych wewnątrznaczyniowo z powodu PNKD z danymi pochodzącymi z duzych badan epidemiologicznych w Polsce dotyczących populacji ogolnej, pacjentow z chorobą naczyn wiencowych i mozgowych. Material i metody. Dokonano retrospektywnej oceny dokumentacji medycznej 73 mezczyzn leczonych po raz pierwszy wewnątrznaczyniowo z powodu PNKD, a stwierdzoną czestośc wystepowania glownych czynnikow ryzyka miazdzycy porownano z danymi z piśmiennictwa. Wyniki. Badani pacjenci z PNKD znamiennie cześciej palili tyton i mieli cukrzyce w porownaniu z wyniki polskich badan epidemiologicznych, takich jak: POLSCREEN, WOBASZ i NATPOL PLUS. Prezentowali oni znamiennie czestsze wystepowania nadciśnienia tetniczego niz w badaniach WOBASZ i NATPOL PLUS, wiekszą czestośc dyslipidemii niz w badaniach POLSCREEN i NATPOL PLUS oraz wiekszą czestośc BMI ≥ 25 kg/m 2 niz w badaniu POLSCREEN i mniejszą niz w badaniu NATPOL PLUS. W porownaniu z pacjentami z chorobą wiencową (CHW) pacjenci z PNKD mieli znamiennie rzadziej nadciśnienie tetnicze, nadwage lub otylośc, ale cześciej palili i mieli dyslipidemie. Wnioski. Pacjenci z PNKD prezentowali wiekszą czestośc i nasilenie czynnikow ryzyka miazdzycy oraz wielopoziomowej manifestacji miazdzycy niz osoby z populacji ogolnej oraz pacjenci z CHW, co wskazuje na koniecznośc poprawy leczenia zachowawczego w tej grupie chorych.
{"title":"Atherosclerosis risk factors in male patients qualified for percutaneous stenting of lower extremity arteries. A retrospective cohort study","authors":"Adrianna Trofimiuk, Klaudia Koza, Paweł Grzelązka, J. Budzyński","doi":"10.12775/MBS.2016.012","DOIUrl":"https://doi.org/10.12775/MBS.2016.012","url":null,"abstract":"Cele. Przewlekle niedokrwienie konczyn dolnych (PNKD) jest trzecim, co do czestości, schorzeniem sercowo- naczyniowym, dotyczącym okolo 20-30% doroslej populacji. Określenie czynnikow ryzyka PNKD jest istotne dla wczesnej diagnozy i wlaściwego leczenia chorych. Celem pracy bylo porownanie czestości wystepowania poszczegolnych czynnikow ryzyka u pacjentow leczonych wewnątrznaczyniowo z powodu PNKD z danymi pochodzącymi z duzych badan epidemiologicznych w Polsce dotyczących populacji ogolnej, pacjentow z chorobą naczyn wiencowych i mozgowych. Material i metody. Dokonano retrospektywnej oceny dokumentacji medycznej 73 mezczyzn leczonych po raz pierwszy wewnątrznaczyniowo z powodu PNKD, a stwierdzoną czestośc wystepowania glownych czynnikow ryzyka miazdzycy porownano z danymi z piśmiennictwa. Wyniki. Badani pacjenci z PNKD znamiennie cześciej palili tyton i mieli cukrzyce w porownaniu z wyniki polskich badan epidemiologicznych, takich jak: POLSCREEN, WOBASZ i NATPOL PLUS. Prezentowali oni znamiennie czestsze wystepowania nadciśnienia tetniczego niz w badaniach WOBASZ i NATPOL PLUS, wiekszą czestośc dyslipidemii niz w badaniach POLSCREEN i NATPOL PLUS oraz wiekszą czestośc BMI ≥ 25 kg/m 2 niz w badaniu POLSCREEN i mniejszą niz w badaniu NATPOL PLUS. W porownaniu z pacjentami z chorobą wiencową (CHW) pacjenci z PNKD mieli znamiennie rzadziej nadciśnienie tetnicze, nadwage lub otylośc, ale cześciej palili i mieli dyslipidemie. Wnioski. Pacjenci z PNKD prezentowali wiekszą czestośc i nasilenie czynnikow ryzyka miazdzycy oraz wielopoziomowej manifestacji miazdzycy niz osoby z populacji ogolnej oraz pacjenci z CHW, co wskazuje na koniecznośc poprawy leczenia zachowawczego w tej grupie chorych.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"19 1","pages":"57-66"},"PeriodicalIF":0.0,"publicationDate":"2016-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83245982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-15DOI: 10.20286/NOVA-JMBS-050104
A. Mardassi, H. Dimassi, S. Nefzaoui, S. Benzarti
Introduction: Tuberculosis remains a real public health problem in Tunisia. Extra-pulmonary localizations account for 20 to 30% of tuberculosis disease, dominated by the node, osseous and urogenital localization. Case Report: The authors present three cases of nasosinusal tuberculosis, an unusual and rare localization of the disease, in a man and 2 women aged respectively of 30, 65 and 36 years. Results: The main symptoms were dominated by nasal obstruction, posterior throwing and dental pain. CT-scan showed a filling of the nasosinusal cavities with various stages of bony lysis. In all the cases, tuberculosis was confirmed histologically after an endoscopic middle meatotomy. Investigations looking for tuberculosis elsewhere were negative in all cases. Treatment was based on anti-tuberculosis drugs during 9 to 12 months. The evolution was favourable in all the cases. Conclusions: Nasosinusal tuberculosis is a rare chronic infection associating often variable levels of bony lysis. Histological exam remains the best way to confirm it. Therapy is based on anti-tuberculosis drugs. Medical investigations must usually search other localizations of the disease.
{"title":"Naso-Sinusal Tuberculosis: 3 Cases Report","authors":"A. Mardassi, H. Dimassi, S. Nefzaoui, S. Benzarti","doi":"10.20286/NOVA-JMBS-050104","DOIUrl":"https://doi.org/10.20286/NOVA-JMBS-050104","url":null,"abstract":"Introduction: Tuberculosis remains a real public health problem in Tunisia. Extra-pulmonary localizations account for 20 to 30% of tuberculosis disease, dominated by the node, osseous and urogenital localization. Case Report: The authors present three cases of nasosinusal tuberculosis, an unusual and rare localization of the disease, in a man and 2 women aged respectively of 30, 65 and 36 years. Results: The main symptoms were dominated by nasal obstruction, posterior throwing and dental pain. CT-scan showed a filling of the nasosinusal cavities with various stages of bony lysis. In all the cases, tuberculosis was confirmed histologically after an endoscopic middle meatotomy. Investigations looking for tuberculosis elsewhere were negative in all cases. Treatment was based on anti-tuberculosis drugs during 9 to 12 months. The evolution was favourable in all the cases. Conclusions: Nasosinusal tuberculosis is a rare chronic infection associating often variable levels of bony lysis. Histological exam remains the best way to confirm it. Therapy is based on anti-tuberculosis drugs. Medical investigations must usually search other localizations of the disease.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73466766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Mrozkowiak, Mirosława Szark-Eckard, H. Żukowska, B. Augustyńska
The main causes of majority of health problems in children and teenagers include incorrect health behaviors and adverse effects of socioeconomic environment. The purpose of this study is to determine the impact of physical activity in the ‘Keep your body straight’ program on incorrect body postures in children aged 7-9 years. Material and methods. 1864 children in classes I-III of primary schools were included in the study. The assessment of posture was conducted in six half-year long editions under the 3-year program using a photogrammetric method and concerned the same group of pupils. Children participated in corrective activities as a part of the ‘Keep your body straight’ program. The above mentioned program positively influenced the torso bending angle to the left and less to the right. A similar effect was observed in the size of the maximum inclination of the atlas vertebra to the left, in the spinous process and to a lesser extent, in the inclination to the right. In addition, a positive effect was noticed in pelvic rotation in the transverse plane. Other features like the angle of shoulder line, the asymmetry of waist triangle height and width, the asymmetry of shoulders, shoulder blades and pelvis in frontal plane did not reveal any significant differences in the process. Conclusions. 1. Corrective activities of the ‘Keep your body straight’ program combined with education of parents are moderately effective means in the correction process of wrong postures in frontal and transverse planes in children of both sexes aged 7-9 years. 2. Physical activity applied within the program significantly influenced the vertical orientation of torso and maximum deviation of the spinous process of vertebrae in the frontal plane and the value of pelvic rotation in the transverse plane. 3. The effectiveness of the program can be enhanced by an individual approach to every ‘advanced incorrect’ posture in a child, which could not be achieved under the program due to insufficient funds of the school.
{"title":"The impact of physical activity in the: „Keep your body straight” program on the selected features of body posturę in frontal and transverse planes in children aged 7-9 years","authors":"M. Mrozkowiak, Mirosława Szark-Eckard, H. Żukowska, B. Augustyńska","doi":"10.12775/MBS.2016.013","DOIUrl":"https://doi.org/10.12775/MBS.2016.013","url":null,"abstract":"The main causes of majority of health problems in children and teenagers include incorrect health behaviors and adverse effects of socioeconomic environment. The purpose of this study is to determine the impact of physical activity in the ‘Keep your body straight’ program on incorrect body postures in children aged 7-9 years. Material and methods. 1864 children in classes I-III of primary schools were included in the study. The assessment of posture was conducted in six half-year long editions under the 3-year program using a photogrammetric method and concerned the same group of pupils. Children participated in corrective activities as a part of the ‘Keep your body straight’ program. The above mentioned program positively influenced the torso bending angle to the left and less to the right. A similar effect was observed in the size of the maximum inclination of the atlas vertebra to the left, in the spinous process and to a lesser extent, in the inclination to the right. In addition, a positive effect was noticed in pelvic rotation in the transverse plane. Other features like the angle of shoulder line, the asymmetry of waist triangle height and width, the asymmetry of shoulders, shoulder blades and pelvis in frontal plane did not reveal any significant differences in the process. Conclusions. 1. Corrective activities of the ‘Keep your body straight’ program combined with education of parents are moderately effective means in the correction process of wrong postures in frontal and transverse planes in children of both sexes aged 7-9 years. 2. Physical activity applied within the program significantly influenced the vertical orientation of torso and maximum deviation of the spinous process of vertebrae in the frontal plane and the value of pelvic rotation in the transverse plane. 3. The effectiveness of the program can be enhanced by an individual approach to every ‘advanced incorrect’ posture in a child, which could not be achieved under the program due to insufficient funds of the school.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"23 1","pages":"35-42"},"PeriodicalIF":0.0,"publicationDate":"2016-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81242087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandra Stachoń, A. Burdukiewicz, J. Pietraszewska, Justyna Andrzejewska, T. Stefaniak, Jaroslaw Maslinski
In judo great significance is attached to the development of strength, which is crucial for performing offensive and defensive actions during fights. Another aspect of strength training is improvement of body build and general physical health of female athletes. The present study aims to estimate the changes of strength and body composition in non-elite female judoists from academic sports clubs after a combined judo and strength training program. The study examined changes in body build and muscle strength in 20 female judoists participating in judo training and additional adaptive strength training. The anthropometric, physical and motoric measurements were performed twice at four months interval, before and after a combined training program. After the completion of the training program, significant increases of about 10 kg in back muscle strength and of about 2 kg in hand grip strength were noted. No increases in muscle mass and body girths were observed; however, fat mass decreased for about 0.6 kg, which was additionally confirmed by skinfolds thickness measurements. Body mass and BMI remained unchanged. The analysis using Sheldon’s somatotypes revealed a tendency towards lower endomorphy among the studied judoists after four months training period. The results of the present study indicate that even experienced but non-elite academic female judoists could improve their back muscle strength, handgrip strength, and body composition by completing the proposed strength training program along with judo training.
{"title":"The changes in body build and strength in female after a 4-month combined judo and strength training program","authors":"Aleksandra Stachoń, A. Burdukiewicz, J. Pietraszewska, Justyna Andrzejewska, T. Stefaniak, Jaroslaw Maslinski","doi":"10.12775/MBS.2016.017","DOIUrl":"https://doi.org/10.12775/MBS.2016.017","url":null,"abstract":"In judo great significance is attached to the development of strength, which is crucial for performing offensive and defensive actions during fights. Another aspect of strength training is improvement of body build and general physical health of female athletes. The present study aims to estimate the changes of strength and body composition in non-elite female judoists from academic sports clubs after a combined judo and strength training program. The study examined changes in body build and muscle strength in 20 female judoists participating in judo training and additional adaptive strength training. The anthropometric, physical and motoric measurements were performed twice at four months interval, before and after a combined training program. After the completion of the training program, significant increases of about 10 kg in back muscle strength and of about 2 kg in hand grip strength were noted. No increases in muscle mass and body girths were observed; however, fat mass decreased for about 0.6 kg, which was additionally confirmed by skinfolds thickness measurements. Body mass and BMI remained unchanged. The analysis using Sheldon’s somatotypes revealed a tendency towards lower endomorphy among the studied judoists after four months training period. The results of the present study indicate that even experienced but non-elite academic female judoists could improve their back muscle strength, handgrip strength, and body composition by completing the proposed strength training program along with judo training.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"16 1","pages":"43-50"},"PeriodicalIF":0.0,"publicationDate":"2016-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82321340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-12DOI: 10.20286/NOVA-JMBS-050186
Muhammad Haidar Hussien, Muhammad Ilham Miskon, A. F. Kamaruddin, Nursyazwanie Ishak
Nowadays, modern technology utilization on food is widely practiced and as a result, there are good and bad impacts of this practice. How they impact the society and why we have to utilize them despite of their impacts? The objective of this article is to determine the good and bad impacts will human globally face when utilizing the modern technology on food. The investigation first focuses on history and evolution of food from ancient until now and the evaluation of the good and bad impact of them on food. The scope also covers on four main classification of food processing related to the use of modern technology; food packaging and storage, food coloring and flavoring, food preservation and food fortification. As such, they are still being used to cater the increasing population demand that need food for survival despite the impacts encountered. The investigation and evaluation methods used are qualitative approach which is conducted through journals, articles, books and literature.
{"title":"The Impacts of Modern Technology on Food","authors":"Muhammad Haidar Hussien, Muhammad Ilham Miskon, A. F. Kamaruddin, Nursyazwanie Ishak","doi":"10.20286/NOVA-JMBS-050186","DOIUrl":"https://doi.org/10.20286/NOVA-JMBS-050186","url":null,"abstract":"Nowadays, modern technology utilization on food is widely practiced and as a result, there are good and bad impacts of this practice. How they impact the society and why we have to utilize them despite of their impacts? The objective of this article is to determine the good and bad impacts will human globally face when utilizing the modern technology on food. The investigation first focuses on history and evolution of food from ancient until now and the evaluation of the good and bad impact of them on food. The scope also covers on four main classification of food processing related to the use of modern technology; food packaging and storage, food coloring and flavoring, food preservation and food fortification. As such, they are still being used to cater the increasing population demand that need food for survival despite the impacts encountered. The investigation and evaluation methods used are qualitative approach which is conducted through journals, articles, books and literature.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90286529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-12DOI: 10.20286/NOVA-JMBS-050185
N. Pirbonyeh, Mitra Zardosht, A. Emami, S. Rostampour, A. Moattari, Abdolkhalegh Keshavarzi
Introduction: Pseudomonas aeruginosa is a bacterium has capability of presenting different policies against antimicrobial agents. These capacities make this bacterium as one of the most important cause of nosocomial infection especially among burned patients. Methods: In this cross sectional study, total of 253 hospitalized burned patients (During September 2013 to November 2014) in Ghotbeddin Shirazi were evaluated for P. aeruginosa. Confirmed isolates tested for Metallo-β-lactamase (MBLs) producing and related genes bla IMPI, II , bla SPM , bla KHM , bla VIM , efflux pump activity, and OprD mutations. Results: From total of 56 (22%) P. aeruginosa isolates, 32 (57.14%) were MBLs while in genetic evaluation, only bla IMPII, bla KHM and bla VIM genes were detected. While 52 (92.8%) isolates had MexAB-OprM gene but 44(78.6%) isolates had efflux pump activity. In OprD sequencing evaluation it has been proved that the most imipenem resistance isolates have mutations in this related gene. Based on the results it has been proved that the circulating P. aeruginosa isolates in Shiraz burn center are armed with the most potential resistant mechanisms. Conclusion: According to that the most isolates have the potential of express different mechanisms of resistance, it is highly recommended to evaluate the circulating infectious agents periodically and determine their resistant algorithm to control them before being resistant and being dominant in health centers.
{"title":"Emergence of Storm Resistant Mechanisms in Pseudomonas aeruginosa Isolated from Burn Patients Hospitalized in Ghotbeddin Shirazi Burn Hospital","authors":"N. Pirbonyeh, Mitra Zardosht, A. Emami, S. Rostampour, A. Moattari, Abdolkhalegh Keshavarzi","doi":"10.20286/NOVA-JMBS-050185","DOIUrl":"https://doi.org/10.20286/NOVA-JMBS-050185","url":null,"abstract":"Introduction: Pseudomonas aeruginosa is a bacterium has capability of presenting different policies against antimicrobial agents. These capacities make this bacterium as one of the most important cause of nosocomial infection especially among burned patients. Methods: In this cross sectional study, total of 253 hospitalized burned patients (During September 2013 to November 2014) in Ghotbeddin Shirazi were evaluated for P. aeruginosa. Confirmed isolates tested for Metallo-β-lactamase (MBLs) producing and related genes bla IMPI, II , bla SPM , bla KHM , bla VIM , efflux pump activity, and OprD mutations. Results: From total of 56 (22%) P. aeruginosa isolates, 32 (57.14%) were MBLs while in genetic evaluation, only bla IMPII, bla KHM and bla VIM genes were detected. While 52 (92.8%) isolates had MexAB-OprM gene but 44(78.6%) isolates had efflux pump activity. In OprD sequencing evaluation it has been proved that the most imipenem resistance isolates have mutations in this related gene. Based on the results it has been proved that the circulating P. aeruginosa isolates in Shiraz burn center are armed with the most potential resistant mechanisms. Conclusion: According to that the most isolates have the potential of express different mechanisms of resistance, it is highly recommended to evaluate the circulating infectious agents periodically and determine their resistant algorithm to control them before being resistant and being dominant in health centers.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"99 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76735661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-12DOI: 10.20286/NOVA-JMBS-050183
G. Allouch
Introduction: The aim of this study was to establish a description of the water cells area in dromedary camels. Methods: Ten clinically healthy of both sexes and different age, 4-9 years old were used in this study. The rumen was cut and opened, the contents were emptied of the rumen, then washed by running tap water to remove the ingestion. They were preserved in 10% formalin for 3-4 days to study object. Results: This study has shown that the water cells area was consisted of many of the primary, secondary and partially folds confining the longitudinal, transversely cells. Conclusions: The longitudinal and transverse cell forms the water cells which was considered chambers in which water was stored in camel's stomach.
{"title":"Anatomical Study of the Water Cells Area in the Dromedary Camels Rumen (Camelus dromedarius)","authors":"G. Allouch","doi":"10.20286/NOVA-JMBS-050183","DOIUrl":"https://doi.org/10.20286/NOVA-JMBS-050183","url":null,"abstract":"Introduction: The aim of this study was to establish a description of the water cells area in dromedary camels. Methods: Ten clinically healthy of both sexes and different age, 4-9 years old were used in this study. The rumen was cut and opened, the contents were emptied of the rumen, then washed by running tap water to remove the ingestion. They were preserved in 10% formalin for 3-4 days to study object. Results: This study has shown that the water cells area was consisted of many of the primary, secondary and partially folds confining the longitudinal, transversely cells. Conclusions: The longitudinal and transverse cell forms the water cells which was considered chambers in which water was stored in camel's stomach.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87101891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-06-07DOI: 10.20286/NOVA-JMBS-050180
M. Abdelhalim, Y. M. H. Salaheldeen, O. Idris., E. Abdelsalam, M. Sabahelkhier.
Introduction: The experiment was designed to investigate the histopathological changes in rat’s tissues due to the effect of the trihalomethane (THM) -bromoform when administered in drinking water. Methods: A group of male Wistar rat was exposed to trihalomethane-bromoform (TBM) at concentration 750 ppm in their drinking water and dose 38.72 mg/kg per day for a month. Results: The growth rate and food intake were not affected by treatment, but TBM reduced significantly water consumption. Conclusions: This study demonstrate that, the brominated THM-bromoform administered in the drinking water induced cancer to the liver and caused hyperplasia to the urinary bladder beside the nephrotoxicity and the toxicity in small intestine demonstrated in the current study.
{"title":"Histopathological Effect on Different Rat Tissues Induced By the Trihalomethane-Bromoform Administered In Drinking Water","authors":"M. Abdelhalim, Y. M. H. Salaheldeen, O. Idris., E. Abdelsalam, M. Sabahelkhier.","doi":"10.20286/NOVA-JMBS-050180","DOIUrl":"https://doi.org/10.20286/NOVA-JMBS-050180","url":null,"abstract":"Introduction: The experiment was designed to investigate the histopathological changes in rat’s tissues due to the effect of the trihalomethane (THM) -bromoform when administered in drinking water. Methods: A group of male Wistar rat was exposed to trihalomethane-bromoform (TBM) at concentration 750 ppm in their drinking water and dose 38.72 mg/kg per day for a month. Results: The growth rate and food intake were not affected by treatment, but TBM reduced significantly water consumption. Conclusions: This study demonstrate that, the brominated THM-bromoform administered in the drinking water induced cancer to the liver and caused hyperplasia to the urinary bladder beside the nephrotoxicity and the toxicity in small intestine demonstrated in the current study.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91268051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Elster, M. Kułakowski, Maciej Leciejewski, L. Grzelak, Ł. Paczesny
Musculocutaneous flaps play an important role in modern reconstructive surgery. They are useful in the treatment of primary traumatic skin lesions and secondary lesions formed during complicated healing of the surgical wounds. The case of 60 years old woman undergoing complicated healing of the wound after spine surgery is presented. The patient was qualified to spine surgery due to metastatic tumour caused by the lung cancer. The use of pedicled flap facilitated healing of the wound; thus, there was no need to remove implants stabilising pathologically fractured spine. The issue of ‘reconstructive ladder’ is discussed in the paper with various treatment options. Indications, surgical technique and postoperative care are thoroughly discussed providing an overview on this valuable method of treatment which allows a successful termination of complicated wound healing process.
{"title":"The use of pedicled musculocutaneous flap of the trapezius muscle for the treatment of skin defect after two stage thoracic spine stabilisation – case report","authors":"K. Elster, M. Kułakowski, Maciej Leciejewski, L. Grzelak, Ł. Paczesny","doi":"10.12775/MBS.2016.004","DOIUrl":"https://doi.org/10.12775/MBS.2016.004","url":null,"abstract":"Musculocutaneous flaps play an important role in modern reconstructive surgery. They are useful in the treatment of primary traumatic skin lesions and secondary lesions formed during complicated healing of the surgical wounds. The case of 60 years old woman undergoing complicated healing of the wound after spine surgery is presented. The patient was qualified to spine surgery due to metastatic tumour caused by the lung cancer. The use of pedicled flap facilitated healing of the wound; thus, there was no need to remove implants stabilising pathologically fractured spine. The issue of ‘reconstructive ladder’ is discussed in the paper with various treatment options. Indications, surgical technique and postoperative care are thoroughly discussed providing an overview on this valuable method of treatment which allows a successful termination of complicated wound healing process.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"30 1","pages":"29-33"},"PeriodicalIF":0.0,"publicationDate":"2016-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85330503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Estera Rodziewicz, Krzysztof Dymek, Paulina Rypolc, M. Wysocki, Irena Daniluk-Matraś, P. Gałązka
I n t r o d u c t i o n . Melanoma is one of the most malignant cancers; however, melanoma in children is a very rare disease, accounting for only 1% of all new cases of cancer diagnosed annually. The objective of this paper is to present two cases of pediatric melanoma malignum with respect to model of surgical management related to stage of the disease with surgical approach based on current guidelines of American Joint Committee on Cancer (AJCC). C a s e r e p o r t s . In first case of 4-year old girl, the melanotic lesion was on the right arm and sentinel lymph node in in right axillary region. After sentinel lymph node biopsy (SLNB) of right axillary space and histologic diagnosis of confirmed malignancy, the patient was qualified for regional lymphadenectomy. The final staging was IIIC grade, and further therapy with interferon was continued. In the second case of 17-year old boy, with congenital naevus on the right earlobe, a SLNB of the right axillary lymph node was performed. Histologic examination of the lymph node did not reveal metastasis to the lymph node. The final was grade IIA and no further therapy was required. C o n c l u s i o n s . Both patients remain in complete clinical remission for 9 and 12 months after the diagnosis, confirmed by imaging and laboratory examinations. Both cases underline proper therapeutic approach based on radicalization of surgical treatment, sentinel lymph node biopsy followed by regional lymphadenectomy and interferon therapy in case of confirmed metastasis or no further therapy in case of negative histology of sentinel lymph node.
{"title":"Radicalization of surgical treatment in pediatric melanoma malignum","authors":"Estera Rodziewicz, Krzysztof Dymek, Paulina Rypolc, M. Wysocki, Irena Daniluk-Matraś, P. Gałązka","doi":"10.12775/MBS.2016.002","DOIUrl":"https://doi.org/10.12775/MBS.2016.002","url":null,"abstract":"I n t r o d u c t i o n . Melanoma is one of the most malignant cancers; however, melanoma in children is a very rare disease, accounting for only 1% of all new cases of cancer diagnosed annually. The objective of this paper is to present two cases of pediatric melanoma malignum with respect to model of surgical management related to stage of the disease with surgical approach based on current guidelines of American Joint Committee on Cancer (AJCC). C a s e r e p o r t s . In first case of 4-year old girl, the melanotic lesion was on the right arm and sentinel lymph node in in right axillary region. After sentinel lymph node biopsy (SLNB) of right axillary space and histologic diagnosis of confirmed malignancy, the patient was qualified for regional lymphadenectomy. The final staging was IIIC grade, and further therapy with interferon was continued. In the second case of 17-year old boy, with congenital naevus on the right earlobe, a SLNB of the right axillary lymph node was performed. Histologic examination of the lymph node did not reveal metastasis to the lymph node. The final was grade IIA and no further therapy was required. C o n c l u s i o n s . Both patients remain in complete clinical remission for 9 and 12 months after the diagnosis, confirmed by imaging and laboratory examinations. Both cases underline proper therapeutic approach based on radicalization of surgical treatment, sentinel lymph node biopsy followed by regional lymphadenectomy and interferon therapy in case of confirmed metastasis or no further therapy in case of negative histology of sentinel lymph node.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"16 1","pages":"35-39"},"PeriodicalIF":0.0,"publicationDate":"2016-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89544427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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