Pub Date : 2016-07-11DOI: 10.20286/NOVA-JMBS-050205
M. Mazdeh, M. Khazaei, A. Sayad, J. Z. Bagherpour, M. Taheri
Background: A headache is the most common cause of patients referred to the doctor. About 40 percent of people are suffering from a headache for at least once a year. Due to it's the high prevalence and its association with cardiovascular diseases, hypertension was considered as a health problem in industrialized and developing countries. The aim of this study was to investigate the role of blood pressure in patients with a headache referred to the neurological clinic during 2014-2015 in Hamadan. Method: This cross-sectional study was performed to evaluate patients with a headache referred to the neurological clinic. Exclusion criteria included: a headache with a specific cause (a migraine, stroke, chronic daily headache, kidney disease, Diabetes Mellitus, history of heart disease or use of cigarette. The data were entered into the list and then were analyzed by SPSS software through paired T-test and chi-square test. Results: In this study, the 100 patients with a headache (78% females and 22% males) were investigated. The average age of patients was 60.07±13.175 years. The prevalence of stage 1 & 2 hypertension was 85%, and prehypertension prevalence of 7% was reported. Most of the headaches were in the frontal (33 %). Furthermore, the most headaches occur in varied time (70%). There wasn’t a significant correlation between age (P-value=0.698), gender (P-value=0.952), headache and blood pressure. Conclusion: The results obtained from the present study indicated that there was not any significant correlation between a headache and blood pressure, and the prevalence of blood pressure in the patients with a headache was similar to those who do not have headaches. Keywords: Blood Pressure, Hypertension, Headache
{"title":"The role of blood pressures in patients with a headache","authors":"M. Mazdeh, M. Khazaei, A. Sayad, J. Z. Bagherpour, M. Taheri","doi":"10.20286/NOVA-JMBS-050205","DOIUrl":"https://doi.org/10.20286/NOVA-JMBS-050205","url":null,"abstract":"Background: A headache is the most common cause of patients referred to the doctor. About 40 percent of people are suffering from a headache for at least once a year. Due to it's the high prevalence and its association with cardiovascular diseases, hypertension was considered as a health problem in industrialized and developing countries. The aim of this study was to investigate the role of blood pressure in patients with a headache referred to the neurological clinic during 2014-2015 in Hamadan. Method: This cross-sectional study was performed to evaluate patients with a headache referred to the neurological clinic. Exclusion criteria included: a headache with a specific cause (a migraine, stroke, chronic daily headache, kidney disease, Diabetes Mellitus, history of heart disease or use of cigarette. The data were entered into the list and then were analyzed by SPSS software through paired T-test and chi-square test. Results: In this study, the 100 patients with a headache (78% females and 22% males) were investigated. The average age of patients was 60.07±13.175 years. The prevalence of stage 1 & 2 hypertension was 85%, and prehypertension prevalence of 7% was reported. Most of the headaches were in the frontal (33 %). Furthermore, the most headaches occur in varied time (70%). There wasn’t a significant correlation between age (P-value=0.698), gender (P-value=0.952), headache and blood pressure. Conclusion: The results obtained from the present study indicated that there was not any significant correlation between a headache and blood pressure, and the prevalence of blood pressure in the patients with a headache was similar to those who do not have headaches. Keywords: Blood Pressure, Hypertension, Headache","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73291256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-10DOI: 10.20286/NOVA-JMBS-050202
Abd Elmoneim O. Elkhalifa, S. Ahmed, S. Ahmed
Kafirin was extracted form a whole high tannins sorghum flour (Fetarita). Different functional properties of produced protein were studied and sorghum flour was used as a control. Results showed that the extracted kafirin has a significant low loose and packed bulk densities compared to the control sorghum flour. The porosity of the control (0.374 g/ml) significantly higher than the extracted kafirin (0.196 g/ml). The Carr index for the kafirin was 20.4%, while it was 39.2% for the sorghum flour Alkaline water retention, as well as water and oil holding capacity of the extracted protein were highly significant than the control, and the results showed that kafirin was highly viscous with a water holding capacity of 2.01 ml H 2 O/g protein, oil holding capacity of 2.10 ml oil/g protein. There is no significant differences between the emulsifying activity of the kafirin and the control, while the kafirin had high emulsifying stability than the control by 11%. No foam capacity and stability were observed for the control, while the kafirin showed 2.75% foam capacity with no foam stability reported. Results shows that the control sorghum flour took longer time (84.9 sec) to completely be wet in cold water than the extracted kafirin (25.0 sec). SEM results of the kafirin supports the development in functional properties. Keywords: Sorghum, Kafirin, Functional properties; SEM.
卡菲林是从一种完整的高单宁高粱粉(Fetarita)中提取的。以高粱粉为对照，研究了所制蛋白质的不同功能特性。结果表明，与对照高粱粉相比，提取的卡菲林具有较低的松散密度和堆积密度。对照品的孔隙度(0.374 g/ml)显著高于提取品的卡非林(0.196 g/ml)。卡菲林的卡尔指数为20.4%，而高粱粉的碱性保水率为39.2%，提取蛋白的持水和持油能力均显著高于对照，结果表明，卡菲林具有高粘性，持水能力为2.01 ml h2o /g蛋白，持油能力为2.10 ml oil/g蛋白。卡非林的乳化活性与对照无显著差异，但其乳化稳定性比对照高11%。对照组没有泡沫容量和稳定性，而卡非林的泡沫容量为2.75%，没有泡沫稳定性的报道。结果表明，对照高粱粉在冷水中完全浸湿的时间(84.9秒)比提取的高粱粉(25.0秒)长。扫描电镜结果支持了其功能性质的发展。关键词:高粱;卡菲林;功能特性;扫描电镜。
{"title":"Some Functional Properties of Kafirin Extracted from a- High- Tannin Sorghum Cultivar","authors":"Abd Elmoneim O. Elkhalifa, S. Ahmed, S. Ahmed","doi":"10.20286/NOVA-JMBS-050202","DOIUrl":"https://doi.org/10.20286/NOVA-JMBS-050202","url":null,"abstract":"Kafirin was extracted form a whole high tannins sorghum flour (Fetarita). Different functional properties of produced protein were studied and sorghum flour was used as a control. Results showed that the extracted kafirin has a significant low loose and packed bulk densities compared to the control sorghum flour. The porosity of the control (0.374 g/ml) significantly higher than the extracted kafirin (0.196 g/ml). The Carr index for the kafirin was 20.4%, while it was 39.2% for the sorghum flour Alkaline water retention, as well as water and oil holding capacity of the extracted protein were highly significant than the control, and the results showed that kafirin was highly viscous with a water holding capacity of 2.01 ml H 2 O/g protein, oil holding capacity of 2.10 ml oil/g protein. There is no significant differences between the emulsifying activity of the kafirin and the control, while the kafirin had high emulsifying stability than the control by 11%. No foam capacity and stability were observed for the control, while the kafirin showed 2.75% foam capacity with no foam stability reported. Results shows that the control sorghum flour took longer time (84.9 sec) to completely be wet in cold water than the extracted kafirin (25.0 sec). SEM results of the kafirin supports the development in functional properties. Keywords: Sorghum, Kafirin, Functional properties; SEM.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87590644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-10DOI: 10.20286/NOVA-JMBS-050201
N. Mohamed, Mohieldin Omer
Background: The study entailed a quantitative assessment of serum total protein, albumin, globulin, and albumin. Method: globulin ratio in individuals who diagnosed positively with typhoid fever and detection any alteration in plasma protein in receptiveness to typhoid titers. One hundred positively diagnosed with typhoid infection mean age (41.5 ± 2.1) years on zero day treatments. In addition to healthy one hundred individuals mean age (42.9 ± 1.9) years were recruited in this study. Results: There were significant difference P. value = 0.000 in total protein, serum albumin, serum globulin and A/G ratio for typhoid positive and negative, mean (8.4±0.01,6.8±0.06), (3.5±0.01, 4.1±0.03), (4.9±0.01, 2.8±0.06), (0.7 ± 0.003, 1.5 ± 0.02) respectively. No significant difference, P. value was 0.632, 0.832 and 0.760 serum total protein (7.5 ± 0.92, 7.6 ± 0.79) serum albumin (3.8 ± 0.38, 3.8 ± 0.37) and serum globulin (3.8 ± 0.16, 3.9 ± 0.16) for males and females respectively. Also no significant difference, P. value was 0.11, 0.60, and 0.06 serum total protein (8.4 ± 0.01, 8.4± 0.02) serum albumin (3.5 ± 0.01, 3.5 ± 0.01) and serum globulin (5.0 ± 0.01, 4.9 ± 0.01) for titer 1/160 and titer 1/320. Conclusion: Low albumin level and hypoglycemia should be surveillant when anti typhoid pharmaceutical commenced. Key words: Plasma Proteins, Enterica Serovar Typhi, Sudan
{"title":"Plasma Proteins in Enterica Serovar Typhi patients in Northern Sudan","authors":"N. Mohamed, Mohieldin Omer","doi":"10.20286/NOVA-JMBS-050201","DOIUrl":"https://doi.org/10.20286/NOVA-JMBS-050201","url":null,"abstract":"Background: The study entailed a quantitative assessment of serum total protein, albumin, globulin, and albumin. Method: globulin ratio in individuals who diagnosed positively with typhoid fever and detection any alteration in plasma protein in receptiveness to typhoid titers. One hundred positively diagnosed with typhoid infection mean age (41.5 ± 2.1) years on zero day treatments. In addition to healthy one hundred individuals mean age (42.9 ± 1.9) years were recruited in this study. Results: There were significant difference P. value = 0.000 in total protein, serum albumin, serum globulin and A/G ratio for typhoid positive and negative, mean (8.4±0.01,6.8±0.06), (3.5±0.01, 4.1±0.03), (4.9±0.01, 2.8±0.06), (0.7 ± 0.003, 1.5 ± 0.02) respectively. No significant difference, P. value was 0.632, 0.832 and 0.760 serum total protein (7.5 ± 0.92, 7.6 ± 0.79) serum albumin (3.8 ± 0.38, 3.8 ± 0.37) and serum globulin (3.8 ± 0.16, 3.9 ± 0.16) for males and females respectively. Also no significant difference, P. value was 0.11, 0.60, and 0.06 serum total protein (8.4 ± 0.01, 8.4± 0.02) serum albumin (3.5 ± 0.01, 3.5 ± 0.01) and serum globulin (5.0 ± 0.01, 4.9 ± 0.01) for titer 1/160 and titer 1/320. Conclusion: Low albumin level and hypoglycemia should be surveillant when anti typhoid pharmaceutical commenced. Key words: Plasma Proteins, Enterica Serovar Typhi, Sudan","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73173368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-09DOI: 10.20286/NOVA-JMBS-050203
M. Sabahelkhier., M. A. Awadllah, A. Idrees, A. Mohammed, M. Idris
This study consists of two parts; the Part one is to evaluate the level of Blood glucose and lipid profile among diabetic patients(121 patients) which are compared with non-diabetic subjects (60 persons) and part two is to correlate lipid profile with cardiovascular abnormalities among type II diabetic patients. The diabetic patients were collected from Jabir Aboeleiz Center for Diabetes (51.9±11.22 years). Sixty healthy non-diabetic subjects were chosen as controls (52.44±10.76years). Blood glucose, total cholesterol (TC), triglycerides (TG) and high density lipoprotein (HDL) were measured by enzymatic colorimetric methods in both groups, and low density lipoprotein cholesterol (LDL) was calculated for each sample. Among diabetic patients, there is high glucose level, serum total cholesterol, triglycerides and LDL cholesterol (p 0.05). The study concluded that higher level of cholesterol, triglyceride and LDL-cholesterol in diabetic patients compared to non-diabetic subjects with lower level of serum HDL-cholesterol in diabetic patient compared to non- diabetic subjects. Keywords: Diabetic, Insulin, Mellitus and lipid.
{"title":"A study of lipid profile Levels of Type II Diabetes Mellitus","authors":"M. Sabahelkhier., M. A. Awadllah, A. Idrees, A. Mohammed, M. Idris","doi":"10.20286/NOVA-JMBS-050203","DOIUrl":"https://doi.org/10.20286/NOVA-JMBS-050203","url":null,"abstract":"This study consists of two parts; the Part one is to evaluate the level of Blood glucose and lipid profile among diabetic patients(121 patients) which are compared with non-diabetic subjects (60 persons) and part two is to correlate lipid profile with cardiovascular abnormalities among type II diabetic patients. The diabetic patients were collected from Jabir Aboeleiz Center for Diabetes (51.9±11.22 years). Sixty healthy non-diabetic subjects were chosen as controls (52.44±10.76years). Blood glucose, total cholesterol (TC), triglycerides (TG) and high density lipoprotein (HDL) were measured by enzymatic colorimetric methods in both groups, and low density lipoprotein cholesterol (LDL) was calculated for each sample. Among diabetic patients, there is high glucose level, serum total cholesterol, triglycerides and LDL cholesterol (p 0.05). The study concluded that higher level of cholesterol, triglyceride and LDL-cholesterol in diabetic patients compared to non-diabetic subjects with lower level of serum HDL-cholesterol in diabetic patient compared to non- diabetic subjects. Keywords: Diabetic, Insulin, Mellitus and lipid.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90567185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrzej Chęsy, G. Chęsy, W. Sikorski, A. Rakowski, Paweł Rakowski, M. Kuśmierek, K. Dmitruk, M. Tafil-Klawe
Otylośc to problem coraz cześciej wystepujący w polskiej populacji. Przyczyną jest nadmierne dostarczanie energii z pokarmow w stosunku do ilości zuzywanych przez organizm, a takze zbyt mala aktywnośc fizyczna. Czynniki te prowadzą do nadmiernego zwiekszenia ilości tkanki tluszczowej, niekorzystnie wplywającej na stan zdrowia. Celem badania jest ocena skladu ciala kobiet miedzy 50 a 80 rokiem zycia zamieszkujących wojewodztwo kujawsko-pomorskie. W badaniu uczestniczyly 1902 mieszkanki wojewodztwa kujawsko-pomorskiego, ktore podzielono na sześc grup wie-kowych. Oceniono u nich za pomocą metody bioimpedancji elektrycznej poziom masy tluszczowej i beztluszczowej ciala. Określono rowniez zawartośc wody w organizmie i pośrednio poziom podstawowej przemiany materii. Wraz z wiekiem u kobiet nastepuje obnizenie beztluszczowej masy ciala i poziomu wody w organizmie. Obserwuje sie natomiast wzrost masy ciala i jednocześnie zawartości tkanki tluszczowej u kobiet miedzy 50 a 70 rokiem zycia. Powyzej 70 roku zycia tendencja ta ulega odwroceniu i dochodzi do spadku masy ciala i poziomu tkanki tluszczowej. Jednocześnie zaobserwowano, ze wraz z wiekiem poziom podstawowej przemiany materii systematycznie ulega zmniejszeniu w populacji.
{"title":"Body composition analysis in women aged 50-80 in Kujawsko-Pomorskie Voivodeship","authors":"Andrzej Chęsy, G. Chęsy, W. Sikorski, A. Rakowski, Paweł Rakowski, M. Kuśmierek, K. Dmitruk, M. Tafil-Klawe","doi":"10.12775/MBS.2016.016","DOIUrl":"https://doi.org/10.12775/MBS.2016.016","url":null,"abstract":"Otylośc to problem coraz cześciej wystepujący w polskiej populacji. Przyczyną jest nadmierne dostarczanie energii z pokarmow w stosunku do ilości zuzywanych przez organizm, a takze zbyt mala aktywnośc fizyczna. Czynniki te prowadzą do nadmiernego zwiekszenia ilości tkanki tluszczowej, niekorzystnie wplywającej na stan zdrowia. Celem badania jest ocena skladu ciala kobiet miedzy 50 a 80 rokiem zycia zamieszkujących wojewodztwo kujawsko-pomorskie. W badaniu uczestniczyly 1902 mieszkanki wojewodztwa kujawsko-pomorskiego, ktore podzielono na sześc grup wie-kowych. Oceniono u nich za pomocą metody bioimpedancji elektrycznej poziom masy tluszczowej i beztluszczowej ciala. Określono rowniez zawartośc wody w organizmie i pośrednio poziom podstawowej przemiany materii. Wraz z wiekiem u kobiet nastepuje obnizenie beztluszczowej masy ciala i poziomu wody w organizmie. Obserwuje sie natomiast wzrost masy ciala i jednocześnie zawartości tkanki tluszczowej u kobiet miedzy 50 a 70 rokiem zycia. Powyzej 70 roku zycia tendencja ta ulega odwroceniu i dochodzi do spadku masy ciala i poziomu tkanki tluszczowej. Jednocześnie zaobserwowano, ze wraz z wiekiem poziom podstawowej przemiany materii systematycznie ulega zmniejszeniu w populacji.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"26 1","pages":"5-12"},"PeriodicalIF":0.0,"publicationDate":"2016-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84826672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of the study was to assess the severity of mood disorders in women in the first and sixth week postpartum and to determine the incidence of baby blues depending on selected risk factors. Material and methods. 285 postpartum women were enrolled in the study. The research project was divided into two stages (first and sixth week postpartum). The Edinburgh Postnatal Depression Scale (EPDS) was used to assess the severity of mood disorders. The indicator of the presence of disorders was set at ≥ 12 points on the 30-point EPDS scale. In order to determine the impact of selected independent variables on the dichotomous dependent variable (baby blues), a logistic regression model was used based on the formula. Results. In the first week postpartum, baby blues was found in 23.2% of the postpartum women. The risk for postnatal depression after six weeks postpartum was determined in 17.3% of the women. The odds ratio for baby blues correlated with: unfavorable financial situation of the women (OR=2.56), a family history of mental disorders (OR=3.87), and dissatisfaction with medical care received during childbirth (OR=5.24). Conclusions Cases of baby blues were determined in every fourth woman from the sample group. The risk for postnatal depression was found in 17.3% of women after six weeks postpartum. The odds ratio for baby blues was affected by the following statistically significant factors: unfavorable financial situation of the women, genetic predispositions and dissatisfaction with perinatal medical care.
{"title":"Incidence of postpartum mood disorders depending on selected risk factors – a logistic regression model","authors":"Marzena Kaźmierczak, Grażyna Gebuza, Estera Mieczkowska, Małgorzata Gierszewska","doi":"10.12775/MBS.2016.010","DOIUrl":"https://doi.org/10.12775/MBS.2016.010","url":null,"abstract":"The aim of the study was to assess the severity of mood disorders in women in the first and sixth week postpartum and to determine the incidence of baby blues depending on selected risk factors. Material and methods. 285 postpartum women were enrolled in the study. The research project was divided into two stages (first and sixth week postpartum). The Edinburgh Postnatal Depression Scale (EPDS) was used to assess the severity of mood disorders. The indicator of the presence of disorders was set at ≥ 12 points on the 30-point EPDS scale. In order to determine the impact of selected independent variables on the dichotomous dependent variable (baby blues), a logistic regression model was used based on the formula. Results. In the first week postpartum, baby blues was found in 23.2% of the postpartum women. The risk for postnatal depression after six weeks postpartum was determined in 17.3% of the women. The odds ratio for baby blues correlated with: unfavorable financial situation of the women (OR=2.56), a family history of mental disorders (OR=3.87), and dissatisfaction with medical care received during childbirth (OR=5.24). Conclusions Cases of baby blues were determined in every fourth woman from the sample group. The risk for postnatal depression was found in 17.3% of women after six weeks postpartum. The odds ratio for baby blues was affected by the following statistically significant factors: unfavorable financial situation of the women, genetic predispositions and dissatisfaction with perinatal medical care.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"134 1","pages":"19-27"},"PeriodicalIF":0.0,"publicationDate":"2016-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83162867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Styczyński, R. Dębski, Anna Krenska, K. Czyżewski, S. Koltan, N. Irga-Jaworska, M. Szalewska, M. Niedźwiecki, J. Stefanowicz, E. Adamkiewicz‐Drożynska, M. Płonowski, E. Leszczyńska, M. Krawczuk-Rybak, T. Ociepa, T. Urasiński, M. Wysocki
Wstep. Transplantacja komorek krwiotworczych (HSCT) jest wazną metodą terapeutyczną w wielu wrodzonych i nabytych chorobach, w tym nowotworowych, zespolach niewydolności szpiku oraz zaburzeniach immunologicznych i metabolicznych. Celem pracy jest analiza wynikow HSCT w pojedynczym ośrodku pediatrycznym w okresie 12 lat. Pacjenci i metodyka. Analizie poddano wyniki przeszczepien wykonanych w latach 2003-2015 w Klinice Pediatrii, Hematologii i Onkologii w Bydgoszczy. Transplantacje analizowano w trzech przedzialach czasowych: 2004-2007, 2008-2011 oraz 2012-2015. Wyniki. Wykonano 318 HSCT, w tym 186 alloge-nicznych (68 zgodnych rodzinnych i 118 od dawcow alternatywnych) oraz 132 autologiczne. Średnie przezycie po HSCT, wyznaczone metodą Kaplana-Meiera wynioslo 8,1 lat. Calkowite prawdopodobienstwo przezycia (pOS) wynioslo 0,64±0,03; pOS po allo-HSCT wynosi 0,62±0,04, a po auto-HSCT 0,67±0,05. Nie wykazano znamiennych roznic w pOS zarowno po allo-HSCT, jak i po auto-HSCT pomiedzy drugim (2008-2011) i trzecim (2012-2015) analizowanym okresie. Jednakze, pOS bylo wyzsze w dru-gim i trzecim okresie w stosunku do okresu pierwszego (2004-2007), zarowno dla wszystkich pacjentow, jak i u pacjentow po auto-HSCT. W grupie pacjentow allo-HSCT, uzyskano wzrost pOS o ponad 20% (43% vs 66% vs 64% w kolejnych przedzialach czasu; ns). Wnioski. Wyniki HSCT uzyskiwane aktualnie w na-szym ośrodku są porownywalne z wynikami podawanymi w miedzynarodowych rejestrach.
{"title":"Improvement of cure after hematopoietic stem cel transplantations in children","authors":"J. Styczyński, R. Dębski, Anna Krenska, K. Czyżewski, S. Koltan, N. Irga-Jaworska, M. Szalewska, M. Niedźwiecki, J. Stefanowicz, E. Adamkiewicz‐Drożynska, M. Płonowski, E. Leszczyńska, M. Krawczuk-Rybak, T. Ociepa, T. Urasiński, M. Wysocki","doi":"10.12775/MBS.2016.009","DOIUrl":"https://doi.org/10.12775/MBS.2016.009","url":null,"abstract":"Wstep. Transplantacja komorek krwiotworczych (HSCT) jest wazną metodą terapeutyczną w wielu wrodzonych i nabytych chorobach, w tym nowotworowych, zespolach niewydolności szpiku oraz zaburzeniach immunologicznych i metabolicznych. Celem pracy jest analiza wynikow HSCT w pojedynczym ośrodku pediatrycznym w okresie 12 lat. Pacjenci i metodyka. Analizie poddano wyniki przeszczepien wykonanych w latach 2003-2015 w Klinice Pediatrii, Hematologii i Onkologii w Bydgoszczy. Transplantacje analizowano w trzech przedzialach czasowych: 2004-2007, 2008-2011 oraz 2012-2015. Wyniki. Wykonano 318 HSCT, w tym 186 alloge-nicznych (68 zgodnych rodzinnych i 118 od dawcow alternatywnych) oraz 132 autologiczne. Średnie przezycie po HSCT, wyznaczone metodą Kaplana-Meiera wynioslo 8,1 lat. Calkowite prawdopodobienstwo przezycia (pOS) wynioslo 0,64±0,03; pOS po allo-HSCT wynosi 0,62±0,04, a po auto-HSCT 0,67±0,05. Nie wykazano znamiennych roznic w pOS zarowno po allo-HSCT, jak i po auto-HSCT pomiedzy drugim (2008-2011) i trzecim (2012-2015) analizowanym okresie. Jednakze, pOS bylo wyzsze w dru-gim i trzecim okresie w stosunku do okresu pierwszego (2004-2007), zarowno dla wszystkich pacjentow, jak i u pacjentow po auto-HSCT. W grupie pacjentow allo-HSCT, uzyskano wzrost pOS o ponad 20% (43% vs 66% vs 64% w kolejnych przedzialach czasu; ns). Wnioski. Wyniki HSCT uzyskiwane aktualnie w na-szym ośrodku są porownywalne z wynikami podawanymi w miedzynarodowych rejestrach.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"10 1","pages":"51-56"},"PeriodicalIF":0.0,"publicationDate":"2016-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72979855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tendinopatia jest powszechnym problemem medycznym o wieloczynnikowej etiologii. Ściegno glowy dlugiej mieśnia dwuglowego ramienia jest podatne na urazy z powodu uwarunkowan anatomicznych oraz biomechanicznych. Celem badania bylo przedstawienie wynikow badania przedmiotowego oraz wynikow artroskopii barku u pacjen-tow z tendinopatią ściegna bicepsa. Badanie podzielono na dwie fazy:przedoperacyjną oraz artroskopową. Pierwsza faza skladala sie z pieciu testow klinicznych,oceny poziomu bolu za pomocą skali VAS oraz analizy historii schorzenia.Druga faza polegala na artroskopii barku z wykonaniem tenotomii lub tenodezy ściegna bicepsa. Badanie przedmiotowe wykazalo, ze najbardziej precy-zyjnym testem do oceny tendinopatii ściegna bicepsa byla tkliwośc w bruździe miedzyguzkowej. Średni wynik w opar-ciu o skale VAS to 7,8. Wywiad schorzenia byl w polowie urazowy, a w polowie o przeciązeniowej etiologii. Artro-skopia barku ujawnila inne schorzenia w stawach ramien-nych, a najczestszą zmianą byly uszkodzenia stozka rotato-row. Wielu autorow podkreśla związek pomiedzy tendinopatią bicepsa a innymi uszkodzeniami barku oraz problematyke precyzji testow klinicznych w diagnostyce tendinopatii. W obliczu licznych zmian towarzyszących tendinopatii bicepsa diagnostyka powinna byc poszerzona o inne badania obrazo-we oraz artroskopie barku uznawaną jako zloty standard.
{"title":"Tendinopathy of the long head of the biceps tendon – physical examination confronted with shoulder arthroscopy findings","authors":"J. Zabrzyński, A. Szumlański","doi":"10.12775/MBS.2016.008","DOIUrl":"https://doi.org/10.12775/MBS.2016.008","url":null,"abstract":"Tendinopatia jest powszechnym problemem medycznym o wieloczynnikowej etiologii. Ściegno glowy dlugiej mieśnia dwuglowego ramienia jest podatne na urazy z powodu uwarunkowan anatomicznych oraz biomechanicznych. Celem badania bylo przedstawienie wynikow badania przedmiotowego oraz wynikow artroskopii barku u pacjen-tow z tendinopatią ściegna bicepsa. Badanie podzielono na dwie fazy:przedoperacyjną oraz artroskopową. Pierwsza faza skladala sie z pieciu testow klinicznych,oceny poziomu bolu za pomocą skali VAS oraz analizy historii schorzenia.Druga faza polegala na artroskopii barku z wykonaniem tenotomii lub tenodezy ściegna bicepsa. Badanie przedmiotowe wykazalo, ze najbardziej precy-zyjnym testem do oceny tendinopatii ściegna bicepsa byla tkliwośc w bruździe miedzyguzkowej. Średni wynik w opar-ciu o skale VAS to 7,8. Wywiad schorzenia byl w polowie urazowy, a w polowie o przeciązeniowej etiologii. Artro-skopia barku ujawnila inne schorzenia w stawach ramien-nych, a najczestszą zmianą byly uszkodzenia stozka rotato-row. Wielu autorow podkreśla związek pomiedzy tendinopatią bicepsa a innymi uszkodzeniami barku oraz problematyke precyzji testow klinicznych w diagnostyce tendinopatii. W obliczu licznych zmian towarzyszących tendinopatii bicepsa diagnostyka powinna byc poszerzona o inne badania obrazo-we oraz artroskopie barku uznawaną jako zloty standard.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"25 1","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2016-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85437694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blanka Dwojaczny, Tomasz Zegarski, W. Sikorski, P. Złomańczuk, M. Tafil-Klawe
Several lines of evidence suggest that being overweight or obese not only impacts the cardiovascular and respiratory systems but also exert a negative effect on the central nervous system. We examined the relationship between body mass index and cognitive performance in three groups of volunteers: obese (17 women; aged 59.88 ± 4.29; BMI 34.08 ± 2.31), overweight (35 women; aged 59.70 ± 4.68; BMI 27.87± 1.44), and normal body weight group (18 women; aged 64.5 ±4.84; BMI 23.53 ± 1.21). To evaluate the cognitive performance in our subjects we used face/name association test. Our data demonstrate that the increased body mass weight may have a negative effect on some cognitive function such as declarative memory.
{"title":"The increased body mass index effect on declarative memory","authors":"Blanka Dwojaczny, Tomasz Zegarski, W. Sikorski, P. Złomańczuk, M. Tafil-Klawe","doi":"10.12775/MBS.2016.011","DOIUrl":"https://doi.org/10.12775/MBS.2016.011","url":null,"abstract":"Several lines of evidence suggest that being overweight or obese not only impacts the cardiovascular and respiratory systems but also exert a negative effect on the central nervous system. We examined the relationship between body mass index and cognitive performance in three groups of volunteers: obese (17 women; aged 59.88 ± 4.29; BMI 34.08 ± 2.31), overweight (35 women; aged 59.70 ± 4.68; BMI 27.87± 1.44), and normal body weight group (18 women; aged 64.5 ±4.84; BMI 23.53 ± 1.21). To evaluate the cognitive performance in our subjects we used face/name association test. Our data demonstrate that the increased body mass weight may have a negative effect on some cognitive function such as declarative memory.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"27 1","pages":"13-18"},"PeriodicalIF":0.0,"publicationDate":"2016-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84069947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandra Oleśna, A. Durczyński, P. Hogendorf, M. Nowicki, J. Strzelczyk
Wprowadzenie. Naduzywanie steroidow anabolicznych jest czeste wśrod kulturystow. Powiązane jest to z wieloma negatywnymi skutkami zdrowotnymi – w tym z rozwojem nowotworow. Opis przypadku. 29-letni kulturysta z rocznym przyjmowaniem duzych dawek steroidow anabolicznych w wywiadzie zaprezentowal kilka epizodow neuroglikopenii z towarzyszącymi utratami przytomności. Wyniki badan obrazowych (USG, MRI, EUS) ujawnily lite ognisko o dośc wyraźnych granicach i średnicy 2cm w trzonie trzustki. Objawy pacjenta ukladaly sie w obraz triady Whipple’a (hiperinsulinemia z towarzyszącą hipoglikemią oraz ustepowanie objawow po podaniu glukozy). Innych odchylen od normy nie zaobserwowano. Pacjent zostal zakwalifiko-wany do leczenia chirurgicznego – przeprowadzono zabieg wyluszczenia guza trzustki. Przebieg pooperacyjny byl powiklany wystąpieniem przetoki trzustkowej, wymagającej reoperacji z zespoleniem trzustkowo-jelitowym sposobem Roux. Badanie histopatologiczne wykazalo obecnośc oto-rebkowanego lagodnego guza neuroendokrynnego. Pacjent byl poddany obserwacji przez 3 lata, w tym czasie nie zaobserwowano nawrotu choroby. Wnioski. Biorąc pod uwage czeste zjawisko zazywania sterydow anabolicznych przez kulturystow, niniejsza praca zwraca uwage na mozliwośc wtornego rozwoju kolejnego, potencjalnie zagrazającego zyciu nowotworu. Guz insulinowy nie byl poprzednio opisywany u sportowcow. Kulturyści powinni byc świadomi pewnych nastepstw zdro-wotnych w związku z zazywaniem steroidow anabolicznych.
{"title":"Anabolic steroid abuse and pancreatic insulinoma","authors":"Aleksandra Oleśna, A. Durczyński, P. Hogendorf, M. Nowicki, J. Strzelczyk","doi":"10.12775/MBS.2016.015","DOIUrl":"https://doi.org/10.12775/MBS.2016.015","url":null,"abstract":"Wprowadzenie. Naduzywanie steroidow anabolicznych jest czeste wśrod kulturystow. Powiązane jest to z wieloma negatywnymi skutkami zdrowotnymi – w tym z rozwojem nowotworow. Opis przypadku. 29-letni kulturysta z rocznym przyjmowaniem duzych dawek steroidow anabolicznych w wywiadzie zaprezentowal kilka epizodow neuroglikopenii z towarzyszącymi utratami przytomności. Wyniki badan obrazowych (USG, MRI, EUS) ujawnily lite ognisko o dośc wyraźnych granicach i średnicy 2cm w trzonie trzustki. Objawy pacjenta ukladaly sie w obraz triady Whipple’a (hiperinsulinemia z towarzyszącą hipoglikemią oraz ustepowanie objawow po podaniu glukozy). Innych odchylen od normy nie zaobserwowano. Pacjent zostal zakwalifiko-wany do leczenia chirurgicznego – przeprowadzono zabieg wyluszczenia guza trzustki. Przebieg pooperacyjny byl powiklany wystąpieniem przetoki trzustkowej, wymagającej reoperacji z zespoleniem trzustkowo-jelitowym sposobem Roux. Badanie histopatologiczne wykazalo obecnośc oto-rebkowanego lagodnego guza neuroendokrynnego. Pacjent byl poddany obserwacji przez 3 lata, w tym czasie nie zaobserwowano nawrotu choroby. Wnioski. Biorąc pod uwage czeste zjawisko zazywania sterydow anabolicznych przez kulturystow, niniejsza praca zwraca uwage na mozliwośc wtornego rozwoju kolejnego, potencjalnie zagrazającego zyciu nowotworu. Guz insulinowy nie byl poprzednio opisywany u sportowcow. Kulturyści powinni byc świadomi pewnych nastepstw zdro-wotnych w związku z zazywaniem steroidow anabolicznych.","PeriodicalId":18339,"journal":{"name":"Medical and Biological Sciences","volume":"13 1","pages":"73-76"},"PeriodicalIF":0.0,"publicationDate":"2016-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82057035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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